Limfoma derajat rendah (low grade):1. Limfositik kecil2. Folikuler

Limfoma hodgkin dg stenberg

Immunohistochemical images of malignant lymphoma are provided below.Sections of the biopsy show a diffuse infiltrate of atypical large lymphoid cells with vesicular nuclei, small nucleoli, and moderate cytoplasm. Small reactive lymphocytes are in the background.An immunohistochemical stain using an antibody directed against CD20 (B-cell marker) shows strong positivity in the large lymphoid cells. This is an example of a diffuse large B-cell lymphoma.Diffuse infiltrate of large lymphoid cells is present, with cleared cytoplasm and hyperchromatic nuclei. Admixed small, reactive lymphocytes also are noted.Immunohistochemical stain using an antibody against CD20 is positive in the large cells; this is a diffuse large B-cell lymphoma.Another example of a diffuse large cell lymphoma. In addition to the large lymphoid cells with moderate cytoplasm, a few cells with lobate nuclei also are seen. Such cells are often observed in large cell lymphoma of the bone.Histologic sections reveal a highly cellular neoplasm composed of cells with a high nucleus-to-cytoplasm ratio, scant cytoplasm, and fine nuclear chromatin. The cells showed immunohistochemical evidence of B-cell lineage and expressed terminal deoxynucleotidyl transferase (TdT), consistent with a precursor B-lymphoblastic lymphoma.Distinguishing lymphoma from Ewing sarcoma can be challenging. An immunohistochemical panel that includes consistent markers for Ewing (CD99) and for lymphoma (terminal deoxynucleotidyl transferase [TdT]) should be performed. Other markers such as CD43, CD79a, CD20, and leukocyte common antigen (LCA) are inconsistently present in lymphoma but should be absent in Ewing sarcoma. Vimentin is positive in the majority of Ewing sarcoma and minority of lymphoma cases.[10, 11]