ERC M

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NAM

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CPAP (VPPCVA)

ERC M

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Gregory GA Kitterman JA Phibbs RH Tooley WH Hamilton WK N Engl J Med 1971 284 133

ERC M

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Polin RA Sahni R Semin Neonatol 20027 379-389 Morley C Davis P Curr Opin Pediatr 200416141-145

ERC M

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Arch Dis Child Fetal Neonatal Ed 2014 Aug 1

Efficacy and safety of bubble CPAP in neonatal care in low and middle income countries a systematic review Martin S Duke T Davis P Abstract INTRODUCTION Forty per cent of global child deaths occur in the neonatal period Low and middle income countries need effective and simple methods to improve hospital-based neonatal care Bubble continuous positive airway pressure (CPAP) may have a role in improving the quality of respiratory support in hospitals in low and middle income countries AIM To examine the evidence for the efficacy and safety of bubble CPAP in neonates with respiratory distress in low and middle income settings METHOD A systematic search (1946-March 2014) was performed of Pubmed Ovid MEDLINE Web of Science Google Scholar and the references of relevant articles Articles meeting inclusion criteria (CPAP for respiratory distress in infants lt28 days of age in hospitals in low and middle income countries) were assessed using Grading of Recommendations Assessment Development and Evaluation and Newcastle-Ottawa Quality Assessment Scale methodology Outcomes included need for mechanical ventilation complications and mortality RESULTS

In three studies the initial use of bubble CPAP compared with oxygen therapy followed by mechanical ventilation if required reduced the

need for mechanical ventilation by 30ndash50 In another three trials comparing bubble CPAP with ventilator CPAP mortality and complication rates were similar while meta-analysis of CPAP failure in these same trials showed a lower failure rate in the bubble CPAP groups (p lt0003) CONCLUSIONS There is evidence that bubble CPAP is safe and reduces the need for mechanical ventilation Further research into the efficacy of bubble CPAP in low-income and middle-income countries is needed

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

SO

NIM

EP ndash

SIB

EN

ndash G

RU

NAM

BEB

CPAP (VPPCVA)

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

SO

NIM

EP ndash

SIB

EN

ndash G

RU

NAM

BEB

Gregory GA Kitterman JA Phibbs RH Tooley WH Hamilton WK N Engl J Med 1971 284 133

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

SO

NIM

EP ndash

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EN

ndash G

RU

NAM

BEB

Polin RA Sahni R Semin Neonatol 20027 379-389 Morley C Davis P Curr Opin Pediatr 200416141-145

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

SO

NIM

EP ndash

SIB

EN

ndash G

RU

NAM

BEB

Arch Dis Child Fetal Neonatal Ed 2014 Aug 1

Efficacy and safety of bubble CPAP in neonatal care in low and middle income countries a systematic review Martin S Duke T Davis P Abstract INTRODUCTION Forty per cent of global child deaths occur in the neonatal period Low and middle income countries need effective and simple methods to improve hospital-based neonatal care Bubble continuous positive airway pressure (CPAP) may have a role in improving the quality of respiratory support in hospitals in low and middle income countries AIM To examine the evidence for the efficacy and safety of bubble CPAP in neonates with respiratory distress in low and middle income settings METHOD A systematic search (1946-March 2014) was performed of Pubmed Ovid MEDLINE Web of Science Google Scholar and the references of relevant articles Articles meeting inclusion criteria (CPAP for respiratory distress in infants lt28 days of age in hospitals in low and middle income countries) were assessed using Grading of Recommendations Assessment Development and Evaluation and Newcastle-Ottawa Quality Assessment Scale methodology Outcomes included need for mechanical ventilation complications and mortality RESULTS

In three studies the initial use of bubble CPAP compared with oxygen therapy followed by mechanical ventilation if required reduced the

need for mechanical ventilation by 30ndash50 In another three trials comparing bubble CPAP with ventilator CPAP mortality and complication rates were similar while meta-analysis of CPAP failure in these same trials showed a lower failure rate in the bubble CPAP groups (p lt0003) CONCLUSIONS There is evidence that bubble CPAP is safe and reduces the need for mechanical ventilation Further research into the efficacy of bubble CPAP in low-income and middle-income countries is needed

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

SO

NIM

EP ndash

SIB

EN

ndash G

RU

NAM

BEB

Gregory GA Kitterman JA Phibbs RH Tooley WH Hamilton WK N Engl J Med 1971 284 133

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

SO

NIM

EP ndash

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EN

ndash G

RU

NAM

BEB

Polin RA Sahni R Semin Neonatol 20027 379-389 Morley C Davis P Curr Opin Pediatr 200416141-145

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

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EN

ndash G

RU

NAM

BEB

Arch Dis Child Fetal Neonatal Ed 2014 Aug 1

Efficacy and safety of bubble CPAP in neonatal care in low and middle income countries a systematic review Martin S Duke T Davis P Abstract INTRODUCTION Forty per cent of global child deaths occur in the neonatal period Low and middle income countries need effective and simple methods to improve hospital-based neonatal care Bubble continuous positive airway pressure (CPAP) may have a role in improving the quality of respiratory support in hospitals in low and middle income countries AIM To examine the evidence for the efficacy and safety of bubble CPAP in neonates with respiratory distress in low and middle income settings METHOD A systematic search (1946-March 2014) was performed of Pubmed Ovid MEDLINE Web of Science Google Scholar and the references of relevant articles Articles meeting inclusion criteria (CPAP for respiratory distress in infants lt28 days of age in hospitals in low and middle income countries) were assessed using Grading of Recommendations Assessment Development and Evaluation and Newcastle-Ottawa Quality Assessment Scale methodology Outcomes included need for mechanical ventilation complications and mortality RESULTS

In three studies the initial use of bubble CPAP compared with oxygen therapy followed by mechanical ventilation if required reduced the

need for mechanical ventilation by 30ndash50 In another three trials comparing bubble CPAP with ventilator CPAP mortality and complication rates were similar while meta-analysis of CPAP failure in these same trials showed a lower failure rate in the bubble CPAP groups (p lt0003) CONCLUSIONS There is evidence that bubble CPAP is safe and reduces the need for mechanical ventilation Further research into the efficacy of bubble CPAP in low-income and middle-income countries is needed

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

SO

NIM

EP ndash

SIB

EN

ndash G

RU

NAM

BEB

Polin RA Sahni R Semin Neonatol 20027 379-389 Morley C Davis P Curr Opin Pediatr 200416141-145

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

SO

NIM

EP ndash

SIB

EN

ndash G

RU

NAM

BEB

Arch Dis Child Fetal Neonatal Ed 2014 Aug 1

Efficacy and safety of bubble CPAP in neonatal care in low and middle income countries a systematic review Martin S Duke T Davis P Abstract INTRODUCTION Forty per cent of global child deaths occur in the neonatal period Low and middle income countries need effective and simple methods to improve hospital-based neonatal care Bubble continuous positive airway pressure (CPAP) may have a role in improving the quality of respiratory support in hospitals in low and middle income countries AIM To examine the evidence for the efficacy and safety of bubble CPAP in neonates with respiratory distress in low and middle income settings METHOD A systematic search (1946-March 2014) was performed of Pubmed Ovid MEDLINE Web of Science Google Scholar and the references of relevant articles Articles meeting inclusion criteria (CPAP for respiratory distress in infants lt28 days of age in hospitals in low and middle income countries) were assessed using Grading of Recommendations Assessment Development and Evaluation and Newcastle-Ottawa Quality Assessment Scale methodology Outcomes included need for mechanical ventilation complications and mortality RESULTS

In three studies the initial use of bubble CPAP compared with oxygen therapy followed by mechanical ventilation if required reduced the

need for mechanical ventilation by 30ndash50 In another three trials comparing bubble CPAP with ventilator CPAP mortality and complication rates were similar while meta-analysis of CPAP failure in these same trials showed a lower failure rate in the bubble CPAP groups (p lt0003) CONCLUSIONS There is evidence that bubble CPAP is safe and reduces the need for mechanical ventilation Further research into the efficacy of bubble CPAP in low-income and middle-income countries is needed

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

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NIM

EP ndash

SIB

EN

ndash G

RU

NAM

BEB

Arch Dis Child Fetal Neonatal Ed 2014 Aug 1

Efficacy and safety of bubble CPAP in neonatal care in low and middle income countries a systematic review Martin S Duke T Davis P Abstract INTRODUCTION Forty per cent of global child deaths occur in the neonatal period Low and middle income countries need effective and simple methods to improve hospital-based neonatal care Bubble continuous positive airway pressure (CPAP) may have a role in improving the quality of respiratory support in hospitals in low and middle income countries AIM To examine the evidence for the efficacy and safety of bubble CPAP in neonates with respiratory distress in low and middle income settings METHOD A systematic search (1946-March 2014) was performed of Pubmed Ovid MEDLINE Web of Science Google Scholar and the references of relevant articles Articles meeting inclusion criteria (CPAP for respiratory distress in infants lt28 days of age in hospitals in low and middle income countries) were assessed using Grading of Recommendations Assessment Development and Evaluation and Newcastle-Ottawa Quality Assessment Scale methodology Outcomes included need for mechanical ventilation complications and mortality RESULTS

In three studies the initial use of bubble CPAP compared with oxygen therapy followed by mechanical ventilation if required reduced the

need for mechanical ventilation by 30ndash50 In another three trials comparing bubble CPAP with ventilator CPAP mortality and complication rates were similar while meta-analysis of CPAP failure in these same trials showed a lower failure rate in the bubble CPAP groups (p lt0003) CONCLUSIONS There is evidence that bubble CPAP is safe and reduces the need for mechanical ventilation Further research into the efficacy of bubble CPAP in low-income and middle-income countries is needed

ERC M

EM

BER ndash

SO

NIP

ED

ndash A

LAPE ndash

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NIM

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EN

ndash G

RU

NAM

BEB

Polin RA Sahni R Semin Neonatol 20027 379-389 Morley C Davis P Curr Opin Pediatr 200416141-145

ERC M

EM

BER ndash

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

ERC M

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Fuente de gases Generador de presioacuten

Interfaz (conexioacuten) paciente-sistema

Aacutecido aceacutetico 025 en agua esteacuteril

ERC M

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Arch Dis Child Fetal Neonatal Ed Jan copy2007 92(1) F18

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Fuente de gases Generador de presioacuten

Interfaz (conexioacuten) paciente-sistema

Aacutecido aceacutetico 025 en agua esteacuteril

ERC M

EM

BER ndash

SO

NIP

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Arch Dis Child Fetal Neonatal Ed Jan copy2007 92(1) F18

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Fuente de gases Generador de presioacuten

Interfaz (conexioacuten) paciente-sistema

Aacutecido aceacutetico 025 en agua esteacuteril

ERC M

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Arch Dis Child Fetal Neonatal Ed Jan copy2007 92(1) F18

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Fuente de gases Generador de presioacuten

Interfaz (conexioacuten) paciente-sistema

Aacutecido aceacutetico 025 en agua esteacuteril

ERC M

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Arch Dis Child Fetal Neonatal Ed Jan copy2007 92(1) F18

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Arch Dis Child Fetal Neonatal Ed Jan copy2007 92(1) F18

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Arch Dis Child Fetal Neonatal Ed Jan copy2007 92(1) F18

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Arch Dis Child Fetal Neonatal Ed Jan copy2007 92(1) F18

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Respir Care 199237(6)582-599 Am Rev Respir Dis 1993147(5)1295-1298

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Jardine LA Inglis GDT Davies MW Cochrane Database of Systematic Reviews 2011 Issue 2

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Arch Dis Child Fetal Neonatal Ed Jan copy2007 92(1) F18

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