بيوشيمي باليني جلسه ششم joshaghanihr@goums.ac.ir

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  • joshaghanihr@goums.ac.ir

  • MW= 62000TetramerEach monomer 1Tyroxine (TBPA)Pre alb RBP + Vit A 182 aaRich of TrpBeta sheet ~ 2 daysBest method for detection = immunologic & nephlometric

  • MW= 60000 ~ 17 daysFunctions:Oncotic pressureCarrier proteinReservoir for aa

  • Carrier protein function of AlbThyroxinBilCortisolCaEstrogensFFAMgCu.

  • Glycolated Alb = FructosamineIn Cycel cell anemia ,Thal & Hemolytic disease is usefulSyndrom nephrotic

  • - 1

  • - 1 (AAT)

    3 phenotype :MM, MZ, ZZEmphysema & cirrhosisAcute phase protein

  • - Gc

  • Gc- (DBP)MW=51000Phenotype: 1-1, 2-2, 1-2Each DBP 1 Vit DSyndrom nephrotic DBP Ca

  • -2

  • -2 (AMG)

    MW = 725000Inhibitor of proteasesSyndrom nephrotic

  • (HP)MW= ~ 4 daysHP HbIn intra venus hemolytic disease Phenotype : 1-1, 1-2, 2-2Acute phase protein

  • (Cer)MW= 132000Cer 6 CuOxidase enzymeFe 2+ Fe 3+Contraceptive drug & pregnancy Acute phase proteinWilson disease

  • Wilson diseaseSerum CerSerum CuUrine CerUrine Cu

    Kayzer Fisher ring

  • -

  • - LDLPosition of band variable in fasting & eating

  • MW=79550A glycoproteinEach transferin 2 FeSerum normal range: 200-400 mg/dl (TIBC)In Iron deficiency & pregnancy Iron TIBC

  • Percipitation of ironCirrhosisDiabetesCardiomyopathyArteritis

  • TIBC= UIBC + Iron

    Saturated percent (%)=(Iron/TIBC)X 100

    In normal condition: 30% transferin saturated

    Asialotransferin in CSF, ..,

  • MW=70000GlycoproteinHemopexine Heme

  • Band between beta & gamaMW= 340000plasma normal range: 100-400 mg/dlDimer (a-, B-, )Acute phase protein ESR

  • CRP

  • CRPMW= 118000-144000GlycoproteinSerum normal range: 470-1340 ng/dlAcute phase protein