lapsus myocard infark type 2 _ english
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8/16/2019 Lapsus Myocard Infark Type 2 _ English
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BAGIAN KARDIOLOGI & LAPORAN KASUS
KEDOKTERAN VASKULAR APRIL 2016
FAKULTAS KEDOKTERANUNIVERSITAS HASANUDDIN
MYOCARDIAL INFARCTION TYPE 2
DISUSUN OLEH :
Sadly Sadikin
SUPERVISOR PEMBIMBING :
dr. Akhtar Fajar Muzakkir, Sp.JP., FIHA
DIBAWAKAN DALAM RANGKA KEPANITERAAN KLINIK
BAGIAN KARDIOLOGI & KEDOKTERAN VASKULAR
FAKULTAS KEDOKTERAN
UNIVERSITAS HASANUDDIN
MAKASSAR
2016
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LEMBAR PENGESAHAN
Yang bertanda tangan di bawah ini menyatakan bahwa
!ama Sadly Sadikin
!IM "### #$ %&'
(ni)er*ita* (ni)er*ita* Ha*anuddin
Judul +apran -a*u* Myardial In/artin 0ype $
telah menyele*aikan tuga* kepaniteraan klinik pada 1agian -ardilgi dan
-edkteran 2a*kular Fakulta* -edkteran (ni)er*ita* Ha*anuddin.
Maka**ar, April $%#&
Super)i*r Pembimbing
dr. Akhtar Fajar Muzakkir, Sp.JP., FIHA
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BAB I
LAPORAN KASUS
A. IDENTITY OF PATIENS
!ame 0n. A-
3ate / 1irth 4 Age $56%76#'&$ 4 85 year* ld
9egi*tratin !. 7###$#
Jb P!S
Marital Statu* MArry
Addre** 3u*un Makwng, +uwu (tara
0elp4HP 6Admi**in %'4%:4$%#&
B. ANAMNESIS
Main "mplaint
"he*t Pain
3i*ea*e Hi*try
+e/t he*t pain e;periened by appr;imately # mnth ag be/re entering the
h*pital and wa* ad)aning abut a day ag. "he*t pain n the le/t *ide /ill liketertusuk , tran*luent bak* ampanied by ul *weat. 3uratin / pain mre
than $% minute*. "he*t pain i* /elt gain weight when in hea)y ati)itie*. !w,
he*t pain had ea*ed. Hi*try / he*t pain pre)iu*ly denied. Shrtne** /
breath i* nt there. ! nau*ea, n )miting heartburn, n headahe, n /e)er
while in the h*pital. <d appetite. 1A1 u*ual, yellw, 1A- nnurrent, A
hi*try / jaundie there. 3enied pre)iu* hi*try / heart di*ea*e.
Pa! I""#$ H%!'(
= Pre)iu* hi*try / *imilar mplain*
= ! hi*try / hyperten*in
= Patient* with a hi*try / hemdialy*i* a*a muh a* $: *ine la*t : mnth
= A hi*try 3M type $ *ine appr;imately #% year* ag
= 3enied pre)iu* hi*try / heart di*ea*e
= ! hi*try / dringking alhl
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C. PHYSICAL E)AMINATION*
<eneral Situatin
1eing *ik 4 nutritin pretty 4 <"S #8 > mp* menti* ?
2ital Sign
6 1ld Prea**ure #%%4&% mmHg
6 Pul*e 9ate @& time*4*end, reguler
6 9e*piratr rate $: time*4*end
6 0emperature >ak*illa? 5&,%"
Head
3e/rmita* !
Fae Simetri* Simetri*
Hair Hard t be re)ked
Size !rmephal
Frm Me*ephal
ye
k*/talmu* !
-njungti)a Anemi* >B?
-rnea 9e/lek* krnea >B?
nptalmu* 0idak ada
Sklera Ikteru* >B?
Pupil I*kr $,8 mm4$,8 mm
ar
aring !rmal
Ctrrhea !
!*e
pi*tak*i* !
9hinrrhea!
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Muth
+ip* 3ry >6? 0ngue 3irty >6?
0n*il 0#60# !t Hyperemia Faring !t Hyperemia
!ek
-<1 ! nlargement 32S 9B: mH$C
0yrid ! nlargement Sti// !ek !
"he*t
Frm +e/t6right *ymmetri eDual*
1rea*t* +e/t6right *ymmetri eDual*, n abnrmalitie*
1etween the rib* +e/t6right *ymmetri eDual*
+ung
Palpa*i Fremitu* +e/t6right *ymmetri eDual*
! 0enderne**
Perku*i* I"S li)er lung marking* I2 dek*tra
9ight behind lung marking* I"S IE
+ung marking* le/t behind I"S E
Au*kulta*i 0he *und / breathing 2e*iular
Additinal *und* rnkhi > 6 ? , wheezing > 6 ?
Heart
In*petin Itu* rdi* de* nt *eem
Palpa*i Itu* rdi* wa* nt palpable
Perku*i +imit tp le/t I"S $ +inea para*ternali* *ini*tra
9ight brder I"S $ linea para*ternali* dek*tra
1ttm right brder I"S : linea para*ternali* de;tra
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1ttm le/t brder I"S : linea medi la)iulari* *ini*tra
Aukulta*i 1J I 4 II regular pure
Heart murmur* > 6 ?
Abdmen
In*petin Flat , tk a breath mtin
Palpa*i +i)er and +ien impalpable
0umr ma** > 6 ? , tenderne** > 6 ?
Perku*i 0impani >B?
Au*kulta*i Peri*taltik >B? nrmal impre**in
k*tremita*
! edema
D. ELEKTROKARDIOGRAM
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+22,0-,2016
Interpretatin
1. Irama Sinu*
2. +aju 9S &: kali4menit
-. 9egularita* 9egular :. Ak*i* !rma;i*
8. <elmbang P %,%:*
6. Inter)al P69 %,#& *
/. 9S -mplek* lebarG %,%@ *. AmplitudG 58 mm
. Segmen S0 S0 depre*i pada lead 25, 2:, 28, 2&,
"nlu*in* *inu* nrmkardi , myardial i*hemia anterlateral in/artin , hypertrphy /
the le/t )entrile
E. LABORATORIUM
0e* Ha*il Satuan !ilai !rmal
Hematlgi 9utin
Hemglbin
Hematkrit
91"
M"H"
7.:
$5.'
$.:5
5%.'
g4dl
mm5
+
#$ 6 #&
:% 6 8:
:.8% 6 &.8%
5$ 5&
+euk*it
0rmb*it
-agula*i
P0
I!9
AP00
#$.$
$8#
','
%,'8
$5,@
#%54Kl
#%54Kl
detik
detik
:,%% #%,%%
#8% 6 :%%
#%6#:
66
$$.%65%.%
Fung*i Hati
S<C0 >AS0?
S<P0 >A+0?
Fung*i <injal
(reum
"reatinine
<luk*a
<3S
::
8:
@%
:.@#
$%8
u4l
u4l
mg4dl
mg4dl
mg4dl
L5@
L:#
#%68%
+>L#.5?GP>L,#.#?
#:%
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<3$PP $7$ mg4dl L$%%
Penanda Jantung
"-
"-6M1
##8
5.@
(4+
(4+
+L#'%, PL#&7
L$8
Imun*erlgi
0rpnin I %,5@ ng L%.%#
lektrlit
!atrium
-alium
-lrida
#5'
5.'
#%'
mml4l
mml4l
mml4l
#5&6#:8
5,868,#
'76###
0abel # +abratry e;aminatin
F. RADIOLOGI
#. Ft 0hra; PA >$:6%56$%#&?
Impre**in
"ardimegaly with *ign* / lung dam
G. ASSESSMENT
#. A"S IM 0ype $$. 3M 0ype $
5. Anemia 9enal
:. S93 n H3 9eguler
H. THERAPY
#. I2F3 !a"l %,' 8%% 4$: jam4I2
$. Alprazlam %.8 mg4$: jam4ral5. 3butamin 5 mg4-g114menit4Syringe Pump
:. 0rimetazidine Hydrhlride 58 mg4#$ jam4ral
8. I**rbid 3initrat %.5 mg4jam4Syringe Pump
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I. PLANNING
#. hardigraphy
$. Perawatan "2"(
. RESUME
+e/t he*t pain e;periened by appr;imately # mnth ag be/re admi**in and wa*
ad)aning mre r le** the la*t day . "he*t pain n the le/t /elt like puntured , penetrating t
the bak with a ld *weat . 3uratin / pain $% min . "he*t pain i* /elt gain weight when
n the m)e . "urrently he*t pain ha* been redued. Cn e;aminatin di*)ered "< *inu*
nrmkardia with H9 &: beat* per minute , with le/t )entriular hypertrphy , i*hemi
myardial in/artin anterlateral . +abratry te*t* /und 0rp I %,5@ , #$,$%% N1" , Hb
7.: , Plt $8#,%%% . "ardimegaly n he*t radigraph* wa* /und with *ign* / lung dam .
D$%#%!%#
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Aute Myardial In/artin > AMI ? i* an interruptin / bld /lw t the heart that
au*e* the heart mu*le ell* die . 0he /lw / bld in the bld )e**el* halted a/ter an aute
rnary lu*in , e;ept /r a *mall amunt / llateral /lw / the bld )e**el* in the
)iinity. 0he mu*le* *urrunding area* wh did nt reei)e bld /lw r /lw )ery little that it
an nt maintain the /untin / the heart mu*le, i* *aid t ha)e in/ark.#
Arding t Alpert>$%#% ? , the di)i*in i* al* alled myardial in/artin r aute myardial in/artin , ba*ed
n the au*e / hetergeneu*, between$
#. In/ark mikard type #
Myardial in/artin urred *pntaneu*ly due t plaDue rupture , /i**ure , er*in r
di**etin / ather*lerti plaDue in the arterie* that make adabang derea*ed bld /lw t
the arterie* . In additin , an inrea*ed need /r and the a)ailability / ;ygen and nutrient* i*
inadeDuate trigger myardial in/artin . Patient* may ha)e a hi*try / hrni "A3 but nt
being b*truted r withut "A3 it*el/
$. In/ark mikard type $
Myardial in/artin i* au*ed by an imbalane between *upply and r need /r ;ygen.
0he au*e / the*e, endthelial dy*/untin , rnary artery *pa*m , rnary embli*m ,
tahyarrhythmia* , bradyarrhythmia* , anemia , hypten*in and hyperten*in with r withut
le/t )entriular enlargement .
5. In/ark mikard type 5
In the*e irum*tane* , the inrea*e bihemial *ign i* nt /und . 0hi* i* due t the patientO* bld *ample i* nt btained r the patient died be/re the bihemial *ignal le)el* had
inrea*ed .
:. a. In/ark mikard type :a
Inrea*ed le)el* / bihemial *ign* / myardial in/artin > eg trpnin ? 5 time*
greater than the nrmal )alue due t the in*tallatin / perutaneu* rnary inter)entin
> P"I ?, whih trigger a myardial in/artin .
b. In/ark mikard type :b
Myardial in/artin ari*ing /rm plaement / *tent thrmb*i* .
8. In/ark mikard type 8
Inrea*ed trpnin le)el* /i)e time* greater than nrmal )alue . 0hi* type / inident
myardial in/artin a**iated with rnary bypa** *urgery .
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0hu* , myardial in/artin, type $ i* an imbalane between *upply and *upply ;ygen
and wa* nt the re*ult / A"S di*ea*e it*el/. keep in mind that in meeting the need* / ardia
;ygen there are 5 /atr* at play ie , ntratility , *y*tli wall ten*in , and heart rate . A* /r
hi* wn ;ygen *upply i* regulated by rnary bld /lw and n the arrying apaity
k*igennya.3
R%3 Fa4!'
1a*ed etilgi nted earlier there are *e)eral ri*k /atr* /r the urrene / myardial
in/artin type $ i* di)ided int traditinal ri*k /atr*, the ri*k /atr* that an be mdi/ied,
and nn6traditinal ri*k /atr*. "n)entinal ri*k /atr* *uh a* age, /amily hi*try, and
rae. 0he mdi/iable ri*k /atr* are dy*lipidemia, hyperten*in, diabete*, *mking,
metabli *yndrme, lak / phy*ial akt)ita*, a* well a* depre**in. A* /r ther au*e* that
au*e thi* di*ea*e ba*ed n a*e *tudie* nduted by <iden, et al $%#: ie, a hi*try /
"A1<, P"I hi*try, heart /ailure, P23, 3iabete* Mellitu*, Hyperten*in, "-3, "CP3, p*t
0IA:
Nmen are *aid t ha)e a higher mrtality than men. 0hi* may be due t wmen
e;periening AMI in lder age, are mre prne t *u//er /rm diabete*, /ten reei)e le**
aggre**i)e therapy. Nmen mre /ten ha)e atypial he*t pain that ame late t the h*pital
and wa* nt allwed t d trmblitik.5
Pa!5"(
Myardial i*hemia ur* when there i* a derea*e in rnary bld /lw wa* *
hea)y /r myardial ;ygen a)ailability i* nt *u//iient /r the need* / ti**ue ;ygen.
1ilgial nept, ba*ed n priniple* / general bilgy / li)er and brain ell*, *hwed tw
pha*e* / adaptatin, the *6alled de/en*e / *hrt6term and lng6term *al)atin. 0he purp*e /
*hrt6term de/en*e mehani*m i* t e*tabli*h a new balane between *upply and demand / ;ygen, with a mbinatin / ntratin dwnregulatin and upregulatin / anaerbi energy
prdutin )ia glyly*i*. +ng6term re*ue until nw nt knwn learly, but that apparently wa*
able t indue hyp;ia i*hemia thrugh a *erie* / ellular *ignal* that au*e the prteti)e
mehani*m* / geneti reprgramming. Nhen the tw pha*e* / thi* adaptatin /ail*, beau*e the
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i*hemia that ur* )ery hea)y there will be ell ner*i*. Adaptatin i* a lng6term prteti)e
re*pn*e t the urrene / i*hemia, *uh a* hibernatin and *tunning 8.
At the n*et / i*hemia with )ery Duikly , there i* an imbalane / energy , e*peially
ph*preatinin , whih keep* the le)el* / Aden*ine 0riph*phat > A0P ? a* lng a* p**ible
thrugh an inrea*e in intraellular inrgani ph*phate . 0he *ub*trate i* al* a majr *ignal t
the dwnregulatin / ntratin . Simultaneu* redutin in energy *tatu* i* a majr *ignal an
inrea*e in anaerbi glyly*i* . C/ anaerbi glyly*i* i* prei*ely btained main *ure /
glygen breakdwn in the aute n*et , immediately /llwed by an inrea*e in glu*e
tran*prt due t the tran*latin / the glu*e tran*prter <+(0 # and <+(0 : t *arklema8.
At the time / i*hemia , there wa* de)elpment / intraellular aid*i* whih
ntributed t the redutin in ntratin* . S wh e;periened i*hemi myardium an
*ur)i)e in a gi)en time thrugh a mbinatin / inhibitin / ntratin and the initiatin /
anaerbi glyly*i* . Nhen dne reper/u*in , there will be impr)ement / mehanial
/untin , and impr)ement / metabli abnrmalitie*8.
I*hemia i* nt re*tred an be in/artin . <enerally pathphy*ilgy ur in tw pha*e* ,
namely a hange in the beginning and the reent hange* . In the initial pha*e , the e)lutin /
in/artin and /untinal di*rder* / the ;ygen derea*e in myardial ntratility . 0he*e
initial hange* it* peak in the urrene / myardial ner*i* kagulati/ within $6: day* .
Alng with a derea*e in myardial ;ygen whih the bld )e**el* that ga)e nutritin terklu*i
, there are rapid *hi/t* /rm aerbi metabli*m tward* anaerbi metabli*m8.
Mithndria are nt able t ;idize /at r prdut / glyly*i*, there/re, a deline in
high6energy ph*phate and anaerbi metabli*m lead* t aumulatin / lati aid. 9edued
high6energy ph*phate *uh a* A0P a//et the !a 4 - A0Pa*e tran*membrane, re*ulting in
inrea*ed intraellular !a and - e;traellular. Membrane leakage and an inrea*ed nentratin
/ e;traellular - au*e hange* in eletrial ptential tran*membrane, predi*p*e* t ptentially
lethal arrhythmia* intraellular alium aumulate* in the damaged myyte* ntribute t the
n*et mehani*m / ellular damage thrugh ati)atin / enzyme* *uh a* lipa*e and prtea*e
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degradatin. "lleti)ely the*e metabli hange* ur the /a*te*t tw minute* a/ter
thrmb*i*. Nithut inter)entin irre)er*ible ell damage will ur within $% minute*, marked
by a membrane de/et*. Prtelyti enzyme* leaking thrugh the myyte membrane, damaging
the *urrunding myardium, and rem)ing marmleule* that *er)e a* marker* / aute
myardial in/artin. Inrea*ed apillary permeability and inrea*ed inter*titial nti pre**ure
>due t leakage / intraellular prtein*? will au*e myardial edema in :6#$ hur*8
9eent hange* ie myardial purge by marphage* and nerti ti**ue by *ar ti**ue
dep*itin . Funtinal hange* al* ur a* a re*ult / IMA in the /rm ntratility di*rder*
and mpliant , *tunning and hibernatin . C;ygen deli)ery t the heart a**iated with rnary
bld /lw , there/re, the abrupt terminatin / reginal per/u*in due t thrmbti lu*in
/ rnary and Duikly *tp the aerbi metabli*m , reatine ph*phate depletin and
anaerbi metabli*m ur* . 0hi* wa* /llwed by the aumulatin / lati netwrk ,
derea*ed A0P prdutin netwrk , atablite aumulatin , inlude* adenine nukletide .
Alng with ntinued i*hemia , ti**ue aid*i* and e//lu; / pta**ium int the e;traellular
*pae . A0P deline in )alue belw that reDuired t maintain the /untin / the membrane ,
au*ing the death / the myyte8.
C"%#%4a" S(78!7
0he linial /eature* / myardial in/artin *ub*ternum generally in the /rm / he*t
pain that /eel* hea)y , pre**ing, like a rumpled and *metime* dijalarkan t the nek , jaw ,
epiga*tri , *hulder r le/t arm , r ju*t di*m/rt in the he*t . IMA i* /ten preeded by an
attak / angina petri* in appr;imately 8% / patient* . Hwe)er , pain in the IMA u*ually
la*t* a /ew hur* t a day , rarely ha)e anything t d with phy*ial ati)ity and u*ually nt
muh redued by admini*tratin / nitrglyerin , u*ually rapid and weak pul*e , patient* al*
/ten e;periene diaphre*i* . In a minrity / patient* > $% t 5% ? IMA de* nt au*ehe*t pain . Silent AMI i* e*peially true in patient* with diabete* mellitu* and hyperten*in a*
well a* in elderly patient*.#,$
D%a#%
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0he diagn*i* / myardial in/artin type $ i* e*tabli*hed ba*ed n a typial hi*try /
he*t pain and i* u*ually a**iated with a nditin that au*e* high ;ygen demand , r a
deline in myardial bld /lw . In angigraphy in general d nt indiate plaDue rupture .
P$7%
Phy*ial e;aminatin *hwed the patient lk* an;iu* and unable t re*t > re*tle**ne** ? r
patient* pre*ent with weak , pale e;tremitie* with ld *weat . 0he mbinatin / *ub*ternal
he*t pain 5% minute* and a lt / *weat. $
Arding t the nditin* / the patient* wh me in , there are tw nditin* that
need t be n*idered , namely , Nhen *upply derea*e* , the anemia with hemglbin L 8.8
mml 4 + /r men and L 8.% mml 4 l /r wmen. Shk > *y*tli L '% mm Hg ? with *ign* /
rgan dy*/untin . 1radyarrhythmia , re*piratry /ailure with arterial ;ygen pre**ure L @ kPa
and linial *ign* / re*piratry /ailure $% min . !e;t up i* the inrea*e in demand G )entriular
tahyarrhythmia* la*ting $% minute* , *upra)entriular tahyarrhythmia* la*ting $% minute* ,
edema pulmnary hyperten*in > *y*tli #&% mm Hg ? with *ign* / pulmnary edema ,
arterial hyperten*in with *y*tli bld pre**ure #&% .
1. Supporting
Inrea*ing the )alue / enzyme* ab)e twie the upper limit / nrmal )alue* indiate the
pre*ene / ardia ner*i*.$
$.# . "-M1 inrea*ed a/ter 5 hur* when there i* myardial in/artin and peak* within
#%6$: hur* and returned t nrmal within $6: day* . Heart *urgery , myarditi* , and eletrial
ardi)er*in an inrea*e "-M1 .
$.$ . "0! there are tw type* / 0 and "0! "0! I. 0hi* enzyme inrea*ed a/ter $ hur*
when there i* myardial in/artin and peak* within #%6$: hur* and "0! 0 an *till be
deteted a/ter 86#: day* while "0! I a/ter 86#% day* .
;aminatin / ther heart enzyme* that myglbin , reatinine kina*e > "- ? , +ati
dehydrgena*e > +3H ?
!n6*pei/i reatin again*t myardial injury i* a plymrphnulear leukyt*i* may
ur within a /ew hur* a/ter the n*et / pain and per*i*t /r 567 day* . +eukyte* an reah
#$,%%%6#8,%%% 4 ul.$
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#$ *andapan "< *huld be per/rmed n all patient* with mplaint* / he*t pain
within #% minute* /rm arri)al in the emergeny rm . "< luminane at inter)al* / 86#%
minute* r #$ *andapan "< mnitring *huld be dne ntinuu*ly t detet ptential
de)elpment / S0 *egment ele)atin . Myardial in/artin type $ an be /und *igni/iant
S0 ele)atin , *metime* enuntered +111 , a* well a* pathlgial $.
! +atin -<
# Anterir le)a*i *egmen S0 dan4atau gelmbang di 2#6
2:428
$ Anter*eptal le)a*i *egmen S0 dan4atau gelmbang di 2#625
5 Anterlateral le)a*i *egmen S0 dan4atau gelmbang di 2#62&
dan I dan a2+
: +ateral le)a*i *egmen S0 dan4atau gelmbang di 2862&
dan in)er*i gelmbang 04ele)a*i S04gelmbang di I
dan a2+
8 In/erlateral le)a*i *egmen S0 dan4atau gelmbang di II, III,
a2F, dan 2862& >kadang6kadang I dan a2+?.
& In/erir le)a*i *egmen S0 dan4atau gelmbang di II, III,
dan a2F
7 In/er*eptal le)a*i *egmen S0 dan4atau gelmbang di II, III,
a2F, 2#625
@ 0rue p*terir <elmbang 9 tinggi di 2#62$ dengan *egmen S0
depre*i di 2#625. <elmbang 0 tegak di 2#62$
' 92 In/ratin le)a*i *egmen S0 di prerdial lead >25962:9?.
1ia*anya ditemukan knjung*i pada in/ark in/erir.
-eadaan ini hanya tampak dalam beberapa jam
pertama in/ark.
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Management
he main bjeti)e management / IMA i* t diagn*e Duikly , relie)e he*t pain , a**e**
and implement *trategie* reper/u*in p**ible , gi)e antithrmbti and anti6 platelet , gi)ing the
drug in)e*tigatin. 0here are *me guideline* > guideline* ? in the management / IMA , butneed* t be adapted t the nditin* / /ailitie* 4 amenitie* at eah )enue and e;pert
apabilitie* that ada.$,& g)ernane /r IM type $ it*el/ i* ba*ed n the etilgi au*e ;ygen
per/u*in di*turbane r the urrene / primary au*a myardial in/artin that reDuired in
the implementatin / r**6*etr llabratin in *l)ing the prblem.
P'4$9'$ $a'"(
a. C;ygen C;ygen *upplementatin *huld be gi)en the patient* with ;ygen *aturatin L'%.
In all patient* withut mpliatin* an be gi)en ;ygen during the /ir*t & hur*.
b. !itrglyerin *ublingual nitrglyerin an be admini*tered *a/ely at a d*e / %.: mg and
an be admini*tered up t three d*e* with an inter)al / 8 minute*.
. . Mrphine )ery e//eti)e in relie)ing he*t pain. Mrphine an be admini*tered at a d*e
/ $6: mg and an be repeated at inter)al* / 86#8 minute* up t a ttal d*e / $% mg.
d. d. A*pirin the ba*i management / patient* *u*peted IM type $ and e//eti)e n the
*petrum / aute rnary *yndrme*. Inhibitin / platelet yl;ygena*e ntinuing
rapid redutin / thrmb;ane A$ le)el* ahie)ed by bual ab*rptin / a*pirin at a d*e
/ #&%65$8 mg in the emergeny rm. Furthermre, gi)en rally at a d*e / 786#&$ mg.
$. e. 1eta blker* I/ mrphine /ailed t redue he*t pain, intra)enu* admini*tratin / beta
blker* an be e//eti)e. 0he bene/it* that ur immediately i/ the drug i* admini*tered
autely and that gi)en the lng term i/ the drug i* gi)en /r *endary pre)entin a/ter
in/artin. Intra)enu* beta blker* impr)e relatin* myardial ;ygen *upply and
demand, redue pain, redue the e;tent / in/artin, and redue the ri*k / )entriular
arrhythmia e)ent* that *eriu*9egimen mmnly gi)en i* metprll 8 mg e)ery $68 minute*
until a ttal / 5 d*e*, with the pr)i* heart rate &% time* per minute, *y*tli bld
pre**ure #%% mmHg, P9 inter)al L%.$: *end* and rakle* n mre than #% m /rm the
diaphragm. Fi/teen minute* a/ter the la*t d*e / I2 /llwed by ral metprll 8% mg e)ery
& hur* /r :@ hur*, /llwed by #%% mg e)ery #$ jam.$,7
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Ma#a$7$#! %# !5$ H8%!a"
I""(
a. Ati)itie* patient* *huld re*t within the /ir*t #$ hur*
b. 3iet patient* *huld be /a*ting r ju*t drink a liDuid with a muth in :6#$ hur* beau*e
/ the ri*k / )miting and a*piratin immediately a/ter myardial in/artin .
. Sedatin patient* reDuiring *edatin during treatment t maintain a perid / inati)ity
with a *edati)e . 3iazepam 8mg , k*azepam #865% mg , r %.86$ mg lrazepam , gi)en 56:
time* 4 day
d. 3ige*ti)e trat > bwel* ? bed re*t and the e//et* / taking narti* /r pain /ten au*e
n*tipatin , * it i* remmended the u*e / *eat kmd bed*ide , high6/iber diet , and
u*e a mild la;ati)e regularly, *uh a* dityl *dium *ulph*uinate > $%% mg 4 day?.$,7
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DAFTAR PUSTAKA
1. <uytn A". Hall, J. 1uku Ajar Fi*ilgi -edkteran. Jakarta <". $%%7
2. Sudy AN, Setiyhadi 1, Alwi I, dkk. 1uku Ajar Ilmu Penyakit 3alam Jilid II di*i 2.
Jakarta Interna Publi*hing. $%#%.
-. Sant* M, Setiawan 0. Penyakit Jantung -rner. "ermin 3unia -edkteran. $%%8G #:7 &6
'
:. 9bbin* S+, "tran 9S, -umar 2. 1uku Ajar Patlgi 9bbin*. Jakarta <". $%%7.8. Sand)al, Yader et al. $%#:. Supply43emand 0ype $ Myardial In/artin. Jurnal / the
Amerian llage / "ardilgy&. 0hyge*en -ri*tian et al. $%#&. 0hird (ni)er*al 3e/initin / Myardial In/artin.
S"4A""F4AHA4NHF. http44ir.ahajurnal*.rg7. Alpert et al. $%#:. 3iagn*ti and 0herapeuti Impliatin* / 0ype $ Myardial In/artin
9e)iew and "mmentary. 0he Amerian Jurnal / Mediine
@. Steln et al. $%#:. 0ype $ Myardial In/artin, Patient "harateri*ti*, Management and
Cutme*. P+CS Cne I*rael