t. pallidum par sa sensibilite et sa specificit6. kellogg
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RErTER TREPONEME: A REVIEW OF THE L1TERATURE 85
T. pallidum par sa sensibilite et sa specificit6. Kellogg& Deacon (1964) ont decouvert une nouvelle tech-nique qui permet l'identification rapide de T. palli-dum. Lamedica & Robert (1957) ont appliqu6 lam6thode de l'hemagglutination A l'etude des anti-corps contre 1'antigene obtenu a partir du tr6po-n6me de Reiter. Giannettasio (195la-b) a utilise,pour des tests intradermiques, des cryolysats de tre-ponemes de Reiter prepares selon la methode deD'Alessandro.
Reiter (1926a) rapporte que Sagel avait considera-blement ameliore I'etat clinique de sujets atteints deparesie en leur injectant un vaccin vivant obtenu Apartir du tr6poneme de Reiter. Miller et al. (1960,1963) et Carpenter et al. (1960) ont immunise deslapins par I'antig6ne proteique de Reiter; cependantapres inoculation de T. pallidum, ils n'ont observ6aucune protection due A I'antigene proteinique.
Meinicke (1956a) a constat6 que l'immunisation delapins par le treponeme de Reiter tue ne produisaitpas d'anticorps specifiques contre T. pallidum, bienque l'immunisation par T. pallidum ait amene laformation d'anticorps vis-a-vis du treponeme deReiter.
Faisant le point en matiere de recherche, Curtis(1964) note que les insuffisances des tests treponemi-ques et l'incapacite actuelle de definir une methodepratique d'immunisation n'ont pu etre vaincues enraison de l'ignorance entourant la structure anti-genique des treponemes et le role des divers anticorpschez 1'hote. Cependant, on a isole, a partir du tr6po-neme de Reiter, diverses fractions, polysaccharidi-que, proteique et lipidiques, et on a pu extraire cer-taines fractions antigeniques a partir d'organismespathogenes. On est en droit d'esperer que ces travauxconduiront "a des tests treponemiques plus precis.
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