the structure and function of ... - helms science...
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The Structure and Function of Macromolecules
I. PolymersWhat is a polymer?
Poly = many; mer = part. A polymer is a large molecule consisting of many smaller sub-units bonded together.
What is a monomer?
A monomer is a sub-unit of a polymer.
II. Classes of Organic Molecules:What are the four classes of organic molecules?
Carbohydrates
Lipids
Proteins
Nucleic Acids
CarbohydratesSugars
Carbo = carbon, hydrate = water; carbohydrates have the molecular formula (CH2O)n
Functions:
Store energy in chemical bonds
Glucose is the most common monosaccharide
Glucose is produced by photosynthetic autotrophs
1. Structure of Monosaccharides
An OH group is attached to each carbon except one, which is double bonded to an oxygen (carbonyl).
Classified according to the size of their carbon chains, varies from 3 to 7 carbons.
Triose = 3 carbons Pentose = 5 carbons Hexose = 6 carbons
Many monosaccharides form rings:
2. Structure of DisaccharidesDouble sugar that consists of 2 monosaccharides
Examples of Disaccharides:Lactose = glucose + galactose Sucrose = glucose + fructose
3. Polysaccharides
Structure: Polymers of a few hundred or a few thousand monosaccharides.
Functions: energy storage molecules or for structural support:
Starch is a plant storage from of energy, easily hydrolyzed to glucose units
Cellulose is a fiber-like structureal material -tough and insoluble - used in plant cell walls
Glycogen is a highly branched chain used by animals to store energy in muscles and the liver.
Chitin is a polysaccharide used as a structural material in arthropod exoskeleton and fungal cell walls.
LipidsStructure: Greasy or oily nonpolar compounds
Functions:
Energy storage
cell membrane structure
Protecting against drying out.
Insulating against cold.
Absorbing shocks.
Regulating cell activities by hormone actions.
1. Structure of Fatty AcidsLong chains of mostly carbon and hydrogen atoms with a -COOH group at one end.
When they are part of lipids, the fatty acids resemble long flexible tails.
Saturated and Unsaturated Fats
Unsaturated fats :◦ liquid at room temp
◦ one or more double bonds between carbons in the fatty acids allows for “kinks” in the tails
◦ most plant fats
Saturated fats:◦ have only single C-C bonds in fatty acid tails
◦ solid at room temp
◦ most animal fats
Saturated fatty
acid
Unsaturated
fatty acid
2. Structure of TriglyceridesGlycerol + 3 fatty acids
3. PhospholipidsStructure: Glycerol + 2 fatty acids
Function: Main structural component of cell membranes, where they arrange in bilayers.
Phospholipids in Water
4. Waxes
Function:
Lipids that serve as coatings for plant parts and as animal coverings.
5. SteroidsStructure: Four carbon rings with no fatty acid tails
Functions:
Component of animal cell membranes
Modified to form sex hormones
ProteinsStructure:
Polypeptide chains
Consist of peptide bonds between 20 possible amino acid monomers
Have a 3 dimensional globular shape
1. Functions of ProteinsEnzymes which accelerate specific chemical reactions up to 10 billion times faster than they would spontaneously occur.
Structural materials, including keratin (the protein found in hair and nails) and collagen (the protein found in connective tissue).
Specific binding, such as antibodies that bind specifically to foreign substances to identify them to the body's immune system.
Specific carriers, including membrane transport proteins that move substances across cell membranes, and blood proteins, such as hemoglobin, that carry oxygen, iron, and other substances through the body.
2. Structure of Amino Acid MonomersConsist of an asymmetric carbon covalently bonded to:
Hydrogen
Amino group
Carboxyl (acid) group
Variable R group specific to each amino acid
Nucleic AcidsTwo kinds:◦ DNA: Deoxyribose Nucleic Acid
double stranded
can self replicate
makes up genes which code for proteins
is passed from one generation to another
◦ RNA: Ribose Nucleic Acid
single stranded
functions in actual synthesis of proteins coded for by DNA
is made from the DNA template molecule
1. Nucleotide StructureBoth DNA and RNA are composed of nucleotide monomers.
Nucleotide = 5 carbon sugar, phosphate, and nitrogenous base
Deoxyribose in DNARibose in RNA
DNA:
• Double helix
• 2 polynucleotide chains
wound into the double helix
• Base pairing between
chains with H bonds
• A - T
• C - G
Summary of the Organic
Molecules: