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Page 1: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015
Page 2: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

The Socially Embedded Researcher: Reasons and

ResponsibilitiesJiin-Yu ChenResearch and Scholarship Integrity Program

Boston CollegeMarch 21, 2015

Page 3: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

What is good research? Produces reliable and accurate

knowledge about natural phenomena and the material world

Generally conducted using accepted methods and standards of practice

Upholds the values critical to sustaining and furthering the practice of research, such as honesty, trustworthiness, accuracy, respect, discernment, and openness

Is this enough?

Page 4: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

Why should researchers examine their works’ social contexts?

Researchers hold a privileged position in society, wielding power and authority. Their work is not isolated from society, but holds significant consequences for it.

The relationship of the inventor with the invention

The research community’s social contract

Stewardship of resources and knowledge

Products and knowledge made can be used for both beneficial and harmful purposes

Page 5: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

Relationship between the inventor and the inventionWithout the active work of a scientist exploring

a particular physical property, it would not be known and therefore these actions create responsibilities that are ethically significant... Whoever makes the effort and succeeds in the discovery receives the kudos, but also must accept the responsibility for having done it: not the responsibility that carries blame for unanticipated consequences, but the responsibility to be there, to participate, to follow the path the discovery takes and to help society use it appropriately.

Reiser and Bulger, “The Social Responsibilities of Biological Scientists”

Page 6: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

Physicists and the Atomic Bomb Development of the atomic bomb by

physicists as part of the effort to end WWII.

On August 6 and 9, 1945, the US dropped atomic bombs on Hiroshima and Nagasaki, respectively. Roughly 200,000 died from injuries sustained.

Most physicists did not oppose the use of nuclear weapons until after they were dropped and the consequences tallied.

In coming to terms with the devastation wrought, the physics community began to reflect on how their work changed society. Many opposed the development of the “Super,” the hydrogen bomb.

J. Robert Oppenheimer, 1944

Atomic bombing of Hiroshima and Nagasaki, respectively

Page 7: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

Social Contract and Stewardship

Researchers’ social contract– Society affords researchers a number of valuable resources

Funding

Autonomy

Authority

Monopoly of knowledge

For these benefits, researchers are responsible for using these resources wisely, in ways that benefit society and do not willfully harm it

Page 8: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

Recombinant DNA and AsilomarResearchers are well-positioned to first identify morally questionable research and be heard by others.

Development of recombinant DNA

Enabled unprecedented study and manipulation of DNA, with many potential benefits

Raised fears about creating novel organisms whose properties and effects could not be predicted

Prominent researchers in the field sent a letter to Science, calling for a world-wide, voluntary moratorium on certain kinds of recombinant DNA research until guidelines and precautions could be formulated

Time cover,April 18, 1977

Credit: David Parkins, Nature, 18 Sept. 2008

Page 9: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

Recombinant DNA and Asilomar

February 23-27, 1975: 155 attendees from research, government, policy, industry, media, and the public convened at Asilomar Conference Center in Pacific Grove, California to discuss how to navigate the risks posed by recombinant DNA, while maximizing the benefits

By the end of the conference, most attendees agreed with the final report that most recombinant DNA research could proceed with appropriate physical and biological safeguards Asilomar Conference Center, Pacific

Grove, CA

Page 10: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

Unintended but potential harms from research– Dual Use Research

of Concern (DURC) The National Science Advisory Board for Biosecurity defined DURC as “research that, based on current understanding, can be reasonably anticipated to provide knowledge, products, or technologies that could be directly misapplied by others to pose a threat to public health and safety, agricultural crops and other plants, animals, the environment, material or national security.”

Some research warrants particular scrutiny because those negative effects are foreseeable, potentially devastating, and a direct consequence of that research.

Page 11: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

DURC– Research on influenza viruses

H5N1: Voluntary moratorium enacted for 2012 when virus reengineered to infect mammals (normally only affects birds)

Gain-of-function research: Since October 2014, federal funding paused for influenza, SARS, and MERS research that could enhance their virulence and transmissibility. Current projects encouraged to observe moratorium.

Page 12: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

How should DURC be approached?

Frameworks

Precautionary principle

Weighing risks and benefits, intrinsic vs. instrumental value of knowledge

Concrete actions

Withholding key details in publications

Restricting access to certain materials

Federal departments to assess risks and benefits of research involving select agents and toxins and develop risk mitigation plan with researchers

Do these actions impinge on the values that research ordinarily strives toward?

Page 13: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

What social responsibilities do researchers have? Use society’s investment wisely to produce

knowledge that is sound and beneficial.

Continually reflect upon the potential social implications of one’s research.

Realize when particular research avenues may directly result in considerable harms for society and take steps to curb or mitigate those harms.

Call attention to problematic areas

Work with other researchers, policy makers, and the public

Good research takes its social context into account when planning, implementing, and discussing its work.

Page 14: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

References Osterholm, Michael T. and David A. Relman. “Creating a Mammalian-

Transmissible A/H5N1 Influenza Virus: Social Contracts, Prudence, and Alternative Perspectives.” Journal of Infectious Diseases 205, no. 11 (2011): 1636-1638.

Reiser, Stanley Joel and Ruth Ellen Bulger. “The Social Responsibilities of Biological Scientists.” Science and Engineering Ethics 3, no. 2 (1997): 137-143.

Resnik, David B. “H5N1 Avian Flu Research and the Ethics of Knowledge.” Hastings Center Report 43, no. 2 (March-April 2013): 22-33.

Schweber, S. S. In the Shadow of the Bomb: Oppenheimer, Bethe, and the Moral Responsibility of the Scientist. Princeton, NJ: Princeton University, 2000.

Shrader-Frechette, Kristin. Ethics of Scientific Research. Lanham, MD: Rowman & Littlefield, 1994.

Swazey, Judith, James R. Sorenson, and Cynthia B. Wong. “Risks and Benefits, Rights and Responsibilities: A History of the Recombinant DNA Research Controversy.” Southern California Law Review 51 (1977-1978): 1019-1078.

Page 15: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015
Page 16: The Socially Embedded Researcher: Reasons and Responsibilities Jiin-Yu Chen Research and Scholarship Integrity Program Boston College March 21, 2015

Questions? Persons to contact at BCStephen Erickson

Research misconductConflict of interestImport-export controlsAnimal and human subjects [email protected]

Sharon Comvalius-GoodardSponsored [email protected]

Jiin-Yu ChenGeneral questions about research and scholarship [email protected]

Jason WenIntellectual [email protected] x21682