the role of the ventrolateral frontal cortex in inhibitory oculomotor control by tim hodgson, marcia...

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The role of the ventrolateral frontal cortex in inhibitory oculomotor control by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas Gutowski, Masud Husain, and Christopher Kennard Brain Volume 130(6):1525-1537 May 24, 2007 © 2007 The Author(s)

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Page 1: The role of the ventrolateral frontal cortex in inhibitory oculomotor control by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas

The role of the ventrolateral frontal cortex in inhibitory oculomotor control

by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas Gutowski, Masud Husain, and Christopher Kennard

BrainVolume 130(6):1525-1537

May 24, 2007

© 2007 The Author(s)

Page 2: The role of the ventrolateral frontal cortex in inhibitory oculomotor control by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas

(A) Schematic of oculomotor rule switching task.

Tim Hodgson et al. Brain 2007;130:1525-1537

© 2007 The Author(s)

Page 3: The role of the ventrolateral frontal cortex in inhibitory oculomotor control by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas

Lesion regions of interest displayed on a transverse view of a standard T1 MRI template image.

Tim Hodgson et al. Brain 2007;130:1525-1537

© 2007 The Author(s)

Page 4: The role of the ventrolateral frontal cortex in inhibitory oculomotor control by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas

(A) Lesion overlap plot for impaired patients in the rule switching task.

Tim Hodgson et al. Brain 2007;130:1525-1537

© 2007 The Author(s)

Page 5: The role of the ventrolateral frontal cortex in inhibitory oculomotor control by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas

(A) Lesion overlap plot for patients classified as impaired in the antisaccade task.

Tim Hodgson et al. Brain 2007;130:1525-1537

© 2007 The Author(s)

Page 6: The role of the ventrolateral frontal cortex in inhibitory oculomotor control by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas

Saccadic latency and error rates in the rule reversal task for left/right VLF damaged patients, other frontal damaged patients and control group in the rule reversal task plotted against trial

after rule change (trial 1 being the first trial following the feedback which instructed a change in rule).

Tim Hodgson et al. Brain 2007;130:1525-1537

© 2007 The Author(s)

Page 7: The role of the ventrolateral frontal cortex in inhibitory oculomotor control by Tim Hodgson, Marcia Chamberlain, Benjamin Parris, Martin James, Nicholas

Relative direction of corrected and uncorrected saccade errors in the rule reversal task for patients with either left or right VLF lesions.

Tim Hodgson et al. Brain 2007;130:1525-1537

© 2007 The Author(s)