SEVERE ACANTHAMOEBA KERATITIS TREATED WITH CORNEAL CROSS-

LINKING

6th International Congress of Corneal Cross-LinkingMilano, Italy

J.I. Recalde, MD.1

Jaime Etxebarria,MD.1,2

Juan A. Duran, MD, PhD.1,3

1 INSTITUTO CLÍNICO-QUIRÚRGICO DE OFTALMOLOGÍA, BILBAO, SPAIN.2 HOSPITAL DE CRUCES, BILBAO,SPAIN.

3BASQUE COUNTRY UNIVERSITY, BILBAO,SPAIN.

6th CXL Congress Milan

PHMB Desomedine

® Brolene®

46 year old female with a culture positive Acanthamoeba corneal infection. No response to medical treatment.

6th CXL Congress Milan

Although complete reepithelialization was delayed (up to a month), symptoms improved drastically.The following day there was no pain, probably due to damage to the corneal nerve endings.

Two months after the procedure, an intumescent cataractous lens

precipitated Phacomorphic Glaucoma.

6th CXL Congress Milan

Penetrating keratoplasty (9x9) and extracapsular cataract extraction along with amniotic membrane application was performed urgently.

Cultures and microscopy of the corneal button were negative for Acanthamoeba. No cysts or trophozoites could be identified.

6th CXL Congress Milan

Two years later, there is limbal insufficiency and optic atrophy related to secondary

glaucoma.

When Acanthamoeba keratitis does not respod to medical therapy, CXL may be used as an alternative.