acanthamoeba keratitis; a clearer vision for the future · acanthamoeba keratitis; a clearer vision...
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Acanthamoeba Keratitis;
A Clearer Vision for the
Future
Professor John Coia and Dr. Claire Alexander
Scottish Parasite Diagnostic and Reference Laboratory
Glasgow Royal Infirmary
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•Caused by Acanthamoeba species
•Associated with contact lens use
•3.7 million contact lens wearers in
the UK
•Incidence in Scotland 149 cases per
million?
Acanthamoeba Keratitis
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Daily Mail May 2015:
“A parasite from my contact lens is gnawing into my eyeball: The
gruesome truth about a scarily common bug…….”
Metro Newspaper Oct 2015:
“Woman nearly has her eye eaten from the inside by horrible
parasite…..”
Recent Media Awareness
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Early phase – responds to antimicrobials
Advanced phase – requires surgery
Clinical Presentation
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Issues
Symptoms
mimic
other diseases
Inaccurate
diagnosis
Inappropriate
treatment
Significant
NHS costs
Ineffective
laboratory
testing
Delayed
diagnosis /
Poor prognosis
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STEP 2
Explore
Testing
Options
STEP 3
Engage
with
Reference
Lab Staff
STEP 4
Develop
Assay
STEP 5
Implement
STEP 1
Engage
with users
& HPS
What Next?
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Review•Audit
•Phone positive findings
Adapt•Patient information
leaflet
•Staff sampling leaflet
•Collection tubes
Share•Workshops
•Training others
•Update
Network•Local, national,
international meetings
Sustainable Commitment
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Improvements
•Improved quality of patient care
•Significant cost savings
•Improved epidemiological data
•Greater awareness and understanding of the disease
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•UK-wide testing
•In-depth molecular profiling
•Inclusion of other ocular pathogens
Vision for Future
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Team photo!
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Scottish Microbiology Reference Laboratories, Glasgow
Diagnostic Directorate, Greater Glasgow and Clyde NHS
Health Protection Scotland
Scottish NHS Ophthalmology Departments and Microbiology
Laboratories
Scottish Virology Microbiology Network
Funding support was provided through NHS National Services Scotland
Acknowledgements