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    Health Research: Statistical tests,evidence, and peer-reviewed

    literature

    Psychological Health

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    Data Analysis: Statistical Significance

    Statistical tests are used to determine the natureof a relationship between 2 variables Is it a TRUE relationship or is it due to chance?

    The p-value is often used as a cut-point forstatistical significance Probability value

    What is the probability that a particular valueoccurred by chance, assuming there is no

    relationship? P

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    Statistical Significance

    p-values come in all forms

    0.05 is the cut off

    Often see 0.01, 0.001, .0000

    NOTE: A smaller p-value does not mean a result ismore significant or stronger

    p

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    Data Analysis: T-tests and Group

    Differences

    Examining differences between two groups

    T-tests (and F-tests) statistical procedures to

    compare two (or more) group means

    Statistical difference between two group

    means yields a p-value

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    Data Analysis: Correlational Coefficient

    and linear relationships

    Linear relationships

    as X changes, Y also changes

    Numerically quantify the relationship between

    the dependent (Y-variable) and independent

    (x-variable)

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    Data Analysis: Correlational Co-

    efficient

    Pearson product-moment correlation (r)

    Measure of the strength of a correlation between

    variables

    Range: -1 to +1

    Positive values=direct relationship

    As one variable increases, related variable also

    increases Negative value=indirect relationship

    As one variable increases, related variable decreases

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    Steps of the Scientific Method:

    Drawing Conclusions

    Drawing conclusions

    CHOCOLATE

    INTAKE

    Body

    fatness

    r= - 0.11

    p-value=0.01

    What can we conclude about chocolate and body weight?

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    Error in Research

    No research study or researcher is perfect

    Measurement error Incorrect use of measurement tools

    Measurement tools that dont measure what they are

    meant to measure Researcher error

    Recording results

    Implementing experimental procedures

    Participant error Memory bias (record incorrectly)

    Social desirability bias

    Misunderstanding of the questions

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    Steps of the Scientific Method

    Observe a phenomenon and ask a question

    Form a hypothesis (is there a causal

    relationship; what do you think will happen?)

    Test hypothesis (research study)

    Analyze data and draw conclusions (statistical

    analysis) Communicate your results (informed

    literature publications, lab report)

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    Steps of the Scientific Method:

    Communication

    Communicate your results

    Publish in peer-reviewed journals

    Present at conferences

    Write lab reports (in this class)

    Communications must be transparent and clear

    Communicate purpose, methods, analysis & results

    Allow for critique and feedback Demonstrate reproducibility

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    Peer-reviewed Scientific Literature

    Peer reviewed (aka refereed)

    Submit research articles to journals for publications

    Expert review and critique research

    Provides check on research promotingpublication of only quality, systematic, and

    informative research

    Peer-reviewed journals Specific subject areas

    Experts on the editorial boards & as reviewers

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    Peer-reviewed (Informed) Literature

    Caveat: All published research is not goodresearch?

    It is still your responsibility as a good consumer to

    critically evaluate the evidence to form your ownopinion

    Methodological weaknesses

    Design issues

    Sources of bias

    Analytical weaknesses

    Data open to interpretation

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    Using Scientific Research

    One study is generally NOT enough evidence

    to support a particular treatment or course of

    action at least not as a standard

    Compile findings from multiple studies of

    different types

    Explain health and diseases

    Identify effective treatments and interventions

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    Evidence Based Practice

    Applying the best available research results(evidence) when making decisions about healthcare. Health care professionals who perform

    evidence-based practice use research evidencealong with clinical expertise and patientpreferences. Systematic reviews (summaries ofhealth care research results) provide information

    that aids in the process of evidence-basedpractice.

    - Agency for Healthcare Quality Researchhttp://effectivehealthcare.ahrq.gov/glossary-of-terms/?filterletter=e

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    Evidence Based Practice

    Relies on scientific research studies

    Based on numerous and varied studies

    Standards of practice are NOT based on One study

    Opinion

    Value

    what weve always done

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    Evidence Pyramid

    For more information (if you are interested) http://researchguides.uic.edu/ebm

    Weak Evidence

    Strongest Evidence

    Systematic Reviews

    Randomized controlled trials

    Cohort studies

    Case-control studies

    Case series

    Case reports

    Ideas, Editorials, Opinions

    Animal research

    In vitro (cell) research

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    Other sources of health information

    Most of us arent reading peer-reviewed journals forhealth information

    Where do we learn about health (besides this class)?

    How do you know when a source is reliable orcredible? Type of source

    Use of experts Use of research to back up facts

    Author/editor credited

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    Psychological Health

    Reading: Chapter 2 Promoting andPreserving your Psychological Health, pg 28-

    55

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    Announcements

    Kresge Library Tutorial

    Lab 1

    Topic: Stress

    Article posted on moodle

    Directions to come

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    Announcements

    Suggestions for note-taking

    Print or download notes prior to class

    Print 4-6 per page and write on the those

    Compare handwritten notes with the notes

    posted on line after class (if you dont print notes)

    Fill in the gaps with your book (or come to office

    hours) If something is NOT in the book/readings I will almost

    always have it written out for you

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    CONTINUING WITH RESEARCHMETHODS

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    Psychological Health

    Mental dimensions of health

    Includes social, emotional & spiritual aspects of well-being

    Involves physical dimension of health

    heart rate

    blood pressure

    digestive system

    weight

    immunity

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    Elements of Psychological Health

    Feeling good about yourself (and your limitations)

    Feeling comfortable with others

    Adequate expressions of respect and compassions

    Controlling tension and anxiety Consciously avoid irrational thoughts, excessive

    excuse making, or blaming others Meet demands of life problem solve

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    Elements of Psychological Health

    Curb hate and guilt

    Maintain positive outlook (more optimistic than

    pessimistic)

    Value diversity

    Enjoy nature and/or conscious of place inuniverse

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    Positive Psychology

    The scientific study of the strengths and virtues

    that enable individuals and communities to thrive.

    The field is founded on the belief that people want

    to lead meaningful and fulfilling lives, to cultivatewhat is best within themselves, and to enhance

    their experiences of love, work, and play.

    From the Positive Psychology Center (UPenn)

    http://www.ppc.sas.upenn.edu

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    Positive Psychology

    Focus on emotional well-being, positive aspects ofcognition Conscious movement away from focus on abnormal psychology

    or mental disorders

    study of happiness, resiliency, strength in character ability to adapt to change and stressful events in healthy and

    flexible ways

    Select goals of positive psychology:

    How to promote happiness and well-being How to improve learning and productivity

    Understanding motivation

    Understanding strength and resilience

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    Positive Psychology

    Recommended readings

    Happiness Hypothesis by Jonathan Haidt Stumbling on Happiness by Dan Gilbert

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    Psychological Health: Influences

    Family

    Encourage, support

    Social Support (friends)

    Community

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    Psychological Health: Influences

    Self-efficacy

    Self-esteem

    Learned helplessness Learned optimism

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    Psychological Health: Influences

    Personality

    Extroversion vs Introversion

    Agreeableness

    Openness to experiences (inquiring intellect)

    Emotional stability

    Conscientiousness

    Resiliency

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    Psychological Health: Influences

    Life-stage

    Adolescence vs adulthood

    Transitions

    Life events

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    MENTAL ILLNESS

    Disruptions in psychological well-being

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    Mental Illness

    Disorders that impair daily functioning by

    affecting

    Diagnostic Criteria

    Diagnostic and Statistical Manual for Mental

    Disorders 5th edition (DSM-V) by the American

    Psychiatry Association

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    Diagnosing Mental Illness

    Diagnostic and Statistical Manual for Mental

    Disorders V by the American Psychiatry

    Association

    http://www.dsm5.org/Pages/Default.aspx

    Sets criteria for

    Diagnosis

    Treatment

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    Treating Mental Illness

    Psychotherapy

    talk-therapy

    Goals of psychotherapy

    Understand

    Provide

    Examples

    Cognitive-behavioral therapy

    Dialectical therapy

    From: http://www.nimh.nih.gov/health/topics/psychotherapies/index.shtml

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    Treating mental illness

    Medications

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    Anxiety Disorders

    Characterized by persistent feelings of threat

    and worry

    Anxiety disorders

    Generalized anxiety disorder

    Panic attacks

    Obsessive compulsive disorder

    Post-traumatic stress disorder

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    Generalized Anxiety Disorder

    Level of anxiety

    Fight or flight symptoms unchecked

    Develops over time

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    Generalized Anxiety Disorder:

    Diagnosis

    Exhibit at least 3 symptoms more days than

    not for at least 6 months

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    Panic Disorders

    Panic attacks

    Sudden onset-Anxiety

    Severe physical symptoms: on- edge to heart

    attack

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    Panic Disorders

    Causes:

    Genetic

    Over-active sympathetic nervous system

    fight or flight

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    Obsessive Compulsive Disorder (OCD)

    Recurrent, unwanted thoughts and repetitive

    behaviors

    Intrusive thoughts

    Rituals

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    Obsessive Compulsive Disorder (OCD)

    Recurrent, unwanted thoughts and repetitive

    behaviors

    Knowledge of irrationality

    Diagnosis

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    Post Traumatic Stress Disorder (PTSD)

    Responses to a previously experienced trauma

    that occur in absence of the event

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    Mood Disorders

    Experience persistent emotional states

    Sadness, despair, euphoria

    interfere with daily or usual functiongin

    Major depression

    Dysthymic disorder

    Bipolar disorder

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    Post Traumatic Stress Disorder (PTSD)

    Event associations

    Physical symptoms

    Dissociation

    f i i

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    More Information on Anxiety

    Disorders

    National Institute of Mental Health

    http://www.nimh.nih.gov/health/topics/anxiety-

    disorders/index.shtml

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    Causes of Mood Disorders

    Interaction of genes, environment, and

    personal history

    Treatment

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    Major Depression

    Most common mood disorder

    Women TWICE as likely to suffer from

    depression

    Depressed mood that interferes with work,relationships, daily functioning

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    Major Depression (DSM-IV)

    Depressed mood and/or loss of interest or pleasure in lifeactivities for at least 2 weeks

    At least five of the following symptoms

    Cause clinically significant impairment in social, work, orother important areas of functioning almost every day

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    Dysthymic Disorder

    Chronic, persistent, mild depression

    Affects 1.5 million American adults (3%)

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    Dysthymic Disorder

    Depressed mood most of the day for more days thannot, for at least 2 years

    Presence of two or more of the following symptoms

    Cause clinically significant impairment in social, work, orother important areas of functioning

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    Bipolar Disorder

    Manic depression

    Severe mood swings

    Highs to lows

    Affects 2.6 % population (5.7 million

    Americans)

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    Bipolar Disorder

    Symptoms of mania

    increased

    decreased need more talkative than usual

    flight of ideas

    distractibility

    psychomotor agitation excessive involvement in pleasurable activities

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    Recognizing Mood Disorders

    Difficult to notice, attend, and talk about

    On-line screening available at Gannett

    http://www.mentalhealthscreening.org/screening

    /?keyword=OAKLAND

    http://www.mentalhealthscreening.org/screening/?keyword=OAKLANDhttp://www.mentalhealthscreening.org/screening/?keyword=OAKLANDhttp://www.mentalhealthscreening.org/screening/?keyword=OAKLANDhttp://www.mentalhealthscreening.org/screening/?keyword=OAKLANDhttp://www.mentalhealthscreening.org/screening/?keyword=OAKLAND
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    Information on Mood Disorders

    National Institute of Mental Health (nimh.gov)

    Depression:

    http://www.nimh.nih.gov/health/topics/depressio

    n/index.shtml Bipolar:

    http://www.nimh.nih.gov/health/topics/bipolar-

    disorder/index.shtml

    American Psychological Association (apa.org)

    http://www.nimh.nih.gov/health/topics/depression/index.shtmlhttp://www.nimh.nih.gov/health/topics/depression/index.shtmlhttp://www.nimh.nih.gov/health/topics/bipolar-disorder/index.shtmlhttp://www.nimh.nih.gov/health/topics/bipolar-disorder/index.shtmlhttp://www.nimh.nih.gov/health/topics/bipolar-disorder/index.shtmlhttp://www.nimh.nih.gov/health/topics/bipolar-disorder/index.shtmlhttp://www.nimh.nih.gov/health/topics/bipolar-disorder/index.shtmlhttp://www.nimh.nih.gov/health/topics/bipolar-disorder/index.shtmlhttp://www.nimh.nih.gov/health/topics/depression/index.shtmlhttp://www.nimh.nih.gov/health/topics/depression/index.shtmlhttp://www.nimh.nih.gov/health/topics/depression/index.shtml
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    Other Mental Health Issues

    Self-injury

    Suicide

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    Self-injury

    Self-harm, self-mutilation, cutting

    NOT a suicide attempt, but a coping

    mechanism

    Often associated with

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    Self-injury

    Preventing behavior while developing coping

    skills

    Identifying triggers

    Identifying plan of action for the trigger

    For more information

    www.selfinjury.org

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    Suicide

    Third leading cause of death among 15-24

    year olds

    90% have a diagnosable mental condition

    Sex differences

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    Risk factors for Suicide

    Risk factors

    Recent loss

    Inability to let go of grief

    History of depression

    Expressed a desire to kill themselves

    Previous suicide attempts

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    Common Signs

    Change in personality

    Sexual dysfunction

    Expressions of Change in

    Preoccupation with

    A direct statement Indirect statement

    Final preparations

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    Suicide Prevention

    What you can do:

    Know warning signs

    Take threats seriously

    Let the person know how much you care about him orher.

    Ask directly.

    Do not belittle the persons feelings.

    Help come up with alternatives.

    Tell someone; do not keep your suspicions to yourself

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    Resources

    National Suicide Prevention Hotline

    1-800-273-8255 Suicidepreventionlifeline.org

    International Suicide Prevention http://suicideprevention.wikia.com/wiki/International_Suicide_Prevention_Directory

    Veterans Crisis Hotline

    1800-273-8255 (1)

    http://www.veteranscrisisline.net

    http://suicideprevention.wikia.com/wiki/International_Suicide_Prevention_Directoryhttp://suicideprevention.wikia.com/wiki/International_Suicide_Prevention_Directory