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General Anatomy of Gastro-IntesT inal System The teeth, Oral cavity, Tongue, Salivary glands, Pharynx. Their vessels and innervation Ivo Klepáček IK

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Page 1: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

General Anatomy

of Gastro-IntesTinal

System The teeth, Oral cavity,

Tongue, Salivary glands,

Pharynx. Their vessels and innervation

Ivo Klepáček IK

Page 2: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

Primordium of the alimentary

canal (GastroInTestinal Canal) GIT devel– systema gastropulmonale –

it develops from the embryonal intestine (entoderm) ; lower respiratory structurses are splitted from intewstine as a tracheobronchial pouch

Ventral (head) intestine part is added to ectodermal pouch

called stomodeum, caudal part of the intestine is added to

ectodermal pouch called proctodeum

Division of the alimentary tract:

1) oral ectodermal segment 2) main entodermal segment 3) caudal ectodermal segment

děivision of the main segment:

ventral gut (foregut – to biliary duct opening) middle gut (midgut – to 2/3 colon) dorsal gut (hindgut – to upper part of the anal canal IK

Page 3: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

Digestive System: Oral cavity (ectodermal origin)

The gut and ist derivatives

(entodermal origin) is

devided in four sections:

1. Pharyngeal gut or pharynx

2. Foregut - esophagus,

stomach, ¼ of duodenum,

liver and gallblader,

pancreas

3. Midgut – ¾ of duodenum,

jejujnum, ilium, colon

caecum, colon ascendens

and 2/3 of colon transversum

4. Hindgut – 1/3 of colon

transversum, colon

descendens, colon

sigmoideum, colon rectum,

canalis analis IK

Page 4: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

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Page 5: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

Alimentary tube

(canal) - general

structure

– tunica mucosa (mucous membrane 1

• epithelium

• lamina propria mucosae (lymph tissue)

• lamina muscularis mucosae

– tunica submucosa (submucous

layer) – vessels, erves (plexus submucosus Meissneri)

– tunica muscularis externa 7

(outer muscular layer) – longitudinal, circular even plexiform; vessels, nerves (plexus myentericus Auerbachi)

– tunica serosa (serous layer) or

tunica adventitia (fibrous layer)

14

salivary glands (glandulae salivares)

pancreas

liver (hepar)

gall bladder and bile ducts (vesica

fellea, ductus choledochus) IK

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Page 7: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

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Page 8: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

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Page 9: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

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Page 10: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

Development of the facial skeleton,

formation of the nasal and oral

cavities Primitive lips:

week 6 - ectoderm ingrowth to mesenchyme in developing

jaw – formation of the labiogingival lamina

lamina splits into two layers separated by groove

central part of upper lip (known as a philtrum develops

from the intermaxillary segment

Primitive oral cavity - stomodeum depression lined by ectoderm and oropharyngeal

membrane

margines:

lower processes from the 1. pharyngeal arch -

mandible

laterally of them upper processes of the 1.

pharyngeal arch - maxilla

superiorly frontonasal process where nasal

placodes appear(pits, sacs and later are

opened to primitive nasal cavity), medial and

lateral nasal processes. IK

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Frontonasal

maxillary

et

mandibular

processes

Face formation

48 day

35 day

14 week

28 day

Philtrum,

nasolacrim

al groove,

cheeks,

maxillae,

nose IK

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The border between the lips and the surrounding skin is

referred to as the vermilion

Labium + mentum

Lip

Chin IK

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Page 15: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

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Page 16: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

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Lp – lamina

propria

mucosae

Sm –

submucosa

Gl –

glandulae

labiales

Gl

Keratinizing epithelial layer continues dorsally as a multilayered cuboid non-keratizing

epithelial layer; Lamina propria mucosae continues as a submucous layer

containing numerous small salivary or mucous glands (compare with soft palate) IK

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c - frenulum

linguae sup.

b,a - plicae

bucco-

alveolares

(buccales) IK

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Palatum durum

Palatum molle

Hard palate

Soft palate

Premaxilla

Maxilla

Os palatinum

Papilla,

rugae (folds)

pits (foveolae)

Lines (crests) IK

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Palate – surface features

Lacey

Incisive papilla

Palatine rugae

Median raphe IK

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Palatal relief with rugae, foveolae and incisal papila IK

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Palate – surface features

Lacey

Hard palate

Soft palate

Median raphe

Fatty zone

Openings of

palatine glands A

H

Hauptmayer line - hard and soft palate connection IK

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Dilates tube Opens tubal orifice

after Petrovicky 2002 IK

Page 34: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

Soft palate

– dorsal view

– ventral view IK

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Chrápání Snoring IK

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Mobile musculoepithelial organ;

Located in the oral cavity and pharynx

Mastication,

Deglutition,

Speech

Squeezing food into pharynx during

swallowing;

Forming words during speaking

Lingua,

tongue,

glossa IK

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Papillae

filiformes

fungiformes

vallatae

Foliatae

Week 6 - 7 IK

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Palatoglossal arch

Palatopharyngeal arch

Triangular fold (plica) (there is r. tonsillaris) IK

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bitter

salty

sour

sweet IK

Page 40: General Anatomy of Gastro-IntesTinal System The teeth ...anat.lf1.cuni.cz/souhrny/aofa9.pdf · General Anatomy of Gastro-IntesTinal System The teeth, Oral cavity, Tongue, Salivary

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Innervation IK

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Floor of the oral cavity lingual frenulum,

sublingual folds,

carunculae

Paralingual

canal =

between

hyoglossus

and

genioglossus IK

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f – plica fimbriata

e – frenulum linguae

g – vena lingualis

profunda

b – caruncula

sublingualis

a – openings of the

sublingual duct on

plica sublingualis

IK

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Styloglossus

Palatoglossus

Hyoglossus

Genioglossus

Extrinsic

lingual

muscles

alter the

position of

the tongue IK

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Intrinsic lingual muscles

alter lingual shape

Superior and inferior longitudinal,

transverse, vertical muscles IK

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Musculi genioglossi are separated by the

lingual septum

Between hyoglossus and genioglossus muscles there is

lingual canal

Lingual septum can be

defibered;

after this abscess cavity

appears IK

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Abscess inside

septum IK

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Salivary glands • Serous cells

• pyramidal, acinous,

• Secerned proteins

• bazofilic, ER, GA

• Apically have

microvili, secretory

granula

• Mucinous cells

• Cuboidal, cylindric,

form tubules

• Secerned mucus

pale granula (fused)

• Viscous secret

distally located inside

ducts IK

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Salivary glands

• Cells of intercalate

ducts

• One-layered

epithelium (flat)

• Lactoferin,, lysozymes

• Intralobular ducts

• Cells of striateed

ducts

• Radially organised,

waved, transport ionts

and participate in

formation of

hypotonic saliva IK

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Salivary glands IK

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after Schumacher 2002 IK

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Glandula parotidea

Sublingualis

Sublingualis anterior

Submandibularis

1:1

3:2 1:3

Relation between serous

and mucous parts IK

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Mucous and serous small

glands

Ebner gl.

serous Weber gl.

mucinous

Anterior

Lingual gl. IK

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Glandula parotis Superficial part

Deep part (processus pharyngeus

Serous tissue

Ductus parotideus (of Stensen) IK

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Glandula

submandibularis

mucoserous tissue

Ductus submandibularis

(of Wharton) IK

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Glandula

sublingualis

Seromucinous tissue

Ductus sublingualis major et

minores (of Santorini) IK

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Pharynx general

arrangement

Nasopharynx (epi-)

Oropharynx (meso-)

Laryngopharynx (hypo-) IK

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Piriform

recess

Pharyngeal recess IK

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* m. stylopharyngeus

** Nervus et vasa laryngea

superiora CN X

Piriform recess

Recessus piriformis

(piriform recess, pouch)

is bordered by aryepiglottic fold

and pharyngoepiglottic fold

Nervus can be irritated through difficult

swallowing or tumor growth IK

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Superior constrictor SC

1 Pars pterygopharyngea

2 Pars buccopharyngea

3 Pars mylopharyngea

4 Pars glossopharyngea

Medius constrictor MC

5 Pars chondropharyngea

6 Pars ceratopharyngea

7 Pars desmopharyngea

Inferior constrictor IC

8 Pars thyropharyngea

9 Pars cricopharyngea

1 2 3

4 5

6

7

8

9

SC: raphe – mandible and hamulus

MC: raphe – hyoid bone and stylohyoid lig.

IC: raphe – cricoid and thyroid cartilages and cricothyroid lig. IK

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Eustachian tube

(auditive tube, salpinx)

relates to

tensor veli palatini (torus

tubarius)

levator veli palatini (torus

levatorius)

and salpingopharyngeus

(from palatopharyngeus)

muscles IK

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Esophageal

(Zenker´s)

diverticle IK

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Spatia around pharynx

lamina prevertebralis fasciae cervicalis + septum styloideum

spatium previscerale

spatium retropharyngeum

spatium parapharyngeum 1. sp. prestyloideum 2. sp. retrostyloideum

spatium paraviscerale IK

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Anulus lymphoideus pharyngis /Waldeyeri/

First barrier protecting body against antigens

in food

Tonsilla pharyngea /1/

Tonsilla tubaria /Gerlachi/ /2/

Tonsilla palatina /2/

Tonsilla lingualis /1/ IK

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Tonsillar lymph circle of Waldeyer

Heinrich Wilhelm

Gottfried

Waldeyer

1836-1921 IK

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Tonsilary system

Tonsills + lymph nodes

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Incomplete capsule

Only efferent lymph vessels

Modified epithelium in

crypts (lymphoepithel or

FAE follicle-associated

epithelium)

Intraepithelial vascularization

Free, T, B lymphocytes,

active immunocompetitive

cells, macrophages,

Langerhans cells, fibrous

stroma

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tonsillectomy IK

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Pharynx

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END IK