15 y.o. cardiac arrest

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    Morning Report

    Erin Fuchs

    July 23, 2014

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    Case

    15 year old previously healthy female

    Visiting from Seattle, Washington

    Spent the last week at camp in Provo Finished camp Friday

    Saturday swimming with family (mom and 3

    sibs) at local pool Sat down in the shade by her family and laid

    down

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    Case contiuned

    After a few minutes (?) twin brother noted her

    to be drooling

    On further exploration -> unresponsive

    CPR started at the scene

    Per mom estimatesthought to be ~2

    minutes prior to CPR initiation

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    Case continued

    AED placed, advised shock -> given

    CPR resumed

    Next cycle, shock not advised therefore CPRcontinued

    EMS arrived, placed their defibrillator, shock

    advised -> given (200 J) Return of Sinus Rhythm

    Intubated and transported to OSH

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    Case continued Outside Hospital

    OSH:

    1L NS (cold)

    >6PVCs/min on rhythm strip

    Propofol started

    Foley placed

    Transported to PCH

    Continued PVCs during transport

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    History PMHx:

    Twin conception, induced at 41 weeks

    Heart murmur that resolved during childhood

    No prior hospitalizations

    PSurgHx:

    Negative

    MEDS:

    None regularly

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    ALLERGIES: NKDA

    IMMS: Needs MMR

    DEVELOPMENT: Normal growth and development per mom

    FHx: Dad with Protein S Deficiency

    Cousin drowned at age 3

    Maternal aunt w/ arrhythmia during stress test

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    SHx:

    Lives in Seattle with parents, twin brother, 2

    siblings (all healthy)

    Involved in schoolreceives great grades

    Wants to become a nutritionist

    Main extracurricular activity is vocal lesions

    Per momno drugs and not sexually active

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    PHYSICAL EXAM

    Vitals: T 36, HR 103, RR 21, BP 111/77 (85), SaO2 100% on

    SIMVWeight: 52kg (42%ile)

    Height: 165cm (65%ile)

    Gen: well nourished, well developed, intubated, sedatedHEENT: NCAT, Pupils 3mm and briskly reactive B/L to light,no EOM, anicteric sclera, TMs not assessed, NP w/odischarge, OP with MMM, otherwise intubated

    NECK: in c-collar, no carotid bruits, no palpable masses orlymphadenopathy

    LUNGS: Vesicular breath sounds in all lung fields, noincreased WOB, symmetric aeration to bases w/o

    wheezing or crackles

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    CV: Regular rate and rhythm, no murmurs, no gallop or

    rub, 2+ dorsalis pedis and radial pulses B/L, cap refill

    >5sec

    ABD: Scaphoid, soft, nontender, nondistended, no HSM,

    no masses

    GU: Normal external genitalia, Tanner stage 5

    EXT: no clubbing, cyanosis, or edema. No gross

    deformities

    SKIN: Pale, no rashes, jaundice, or cyanosis

    NEURO: Spontaneously moving UEnonpurposeful,

    clenching hands B/L, inc tone in all extremities (LE>UE),

    unable to follow commands, no spontaneous eye

    opening, reflexes not assessed, GCS 4T

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    15 year old previously healthy

    female with sudden cardiac arrest

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    Differential Diagnosis CV:

    Aortic Stenosis

    Cardiomyopathy Dilated

    Hypertrophicobstructive

    Arrhythmogenic Rventricular (ARVC)

    Ebstein Anomaly

    Coronary arterydisease:

    MI

    Congenital CAanomaly

    CA embolism

    Coronary arterities Myocardial ischemia

    Tetralogy of Fallot

    Arrythmias Torsades

    V. Fib PVCs

    V. Tach

    WPW Syndrome

    Channelopathies Prolonged QT

    syndrome BrugadasSyndrome

    Ruptured aorticaneurysm (i.e.Marfans)

    ID Myocarditis

    Endocarditis

    Kawasakis

    Meningitis

    Encephalitis

    PULM

    PE

    Asthma

    NEURO Epilepsy

    Intracranialhemorrhage

    MISC Disordered eating

    Trauma

    Simulant/Drug intake DKA

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    Work-Up OSH

    Serum Tox and Urine Tox: NEGATIVE

    CMP: Na 133, K 1.9, Cl 84, CO2 17, Gluc 378, BUN 9, Cr 0.94,Ca 9.8, Prot 7.2, Alb 4.4, Tbili 0.6, Alk Phos 69, ALT 73, AST101

    Coags: PT 14.9, INR 1.2, PTT 23

    CBC: WBC 10 (N52%, L45%, M1%, E1%), Hct 38, Plts 286 UA: Sp Gr 1.015, pH 7.5, Trace hgb, 1+ prot

    ABG @ 1919: 7.47/35/551/25.5

    Lactate 9.9

    CXR: hyperinflated lungs, no fx, no pneumo, noconsolidation or effusion

    CT brain w/o contrast: Normal

    CT Angio chest: No evidence of PE. Symmetric groundglassopacities and bronchial thickening.

    PCH

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    PCH ECHO:

    Mild TV regurg

    Trivial MV regurg

    Normal RV size, mildly dec systolic func Normal LV size, mildly dec systolic func

    EKG: Sinus rhythm w/ occasional PVCs

    Nonspecific T-wave abnormality

    Prolonged QT (524 -> 703 -> 583 -> 600 -> 498 -> 445)

    Phos:

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    Diagnosis? .

    DISORDERED EATING

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    Sudden Cardiac Arrest

    0.5-20 per 100,000 youth

    Higher risk (2-2.5x) of SCA during athletic

    competition/exercise.

    CDC estimates that ~2000 people

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    Warning Signs or symptoms (i.e. chest pain,fatigue, and syncope/lightheadedness)

    Noted by at least 40-70% of individuals prior to SCAor SCD

    MC symptoms:

    Chest pain

    Actual or near syncope Others: Dizziness, palpitations, or dyspnea

    Preceding symptoms of dizziness, chest pain,syncope, palpitations, or dyspnea and a familyhistory of premature, unexpected sudden deathwere noted in 25% to 61% of the studypopulation. Deaths were exertion-related in 8%

    to 33% of cases

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    Studies

    Out-of-Hospital Pediatric Cardiac Arrest: AnEpidemiologic Review and Assessment ofCurrent Knowledge

    Articles from 1966-2004 (41 articles) Outcomes for children 18 or younger

    Pediatric Utstein outcome report guidelines:

    Cessation of cardiac mechanical activity,determined by the inability to palpate a centralpulse, unresponsiveness, and apnea

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    Age (when reported = 15 of 41 studies):

    Range of median age: 1-7 years

    Range of mean age: 7.9 mo5.9 yrs

    22 of 41 studies reported number of pts

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    Outcomes: (Total of 5,363 patients)

    ROSC: 751/2,438 (30.8%)

    Sustained ROSC: 165/594 (27.8%) Survival to admit: 340/1,423 (23.9%)

    Survival to discharge: 647/5,363 (12.1%) -> 6.7%

    Neurologically intact survival: 131/3,272 (4%) -> 2.2%

    Witnessed arrest: (532 of 1,725 = 30.8%)

    Survived to discharge: 13%

    Unwitnessed arrest:

    Survived to discharge: 4.6%

    Bystander CPR associated with survival todischarge (although inconsistent result amongst

    studies)

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    Neurologic status post-cardiac arrest

    Bystander CPR (ROSC prior to EMS arrival)

    Largely under-represented in studies published

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    Resources

    Berger, S. Sudden cardiac arrest and death in

    children. UpToDate. June 30, 2014.

    Donoghue, A., Nadkami, V., Berg, R., et al. Out-

    of-hospital pediatric cardiac arrest: anepidemiologic review and assessment of currentknowledge. Annuals of Emergency Medicine.

    2005; 46, 512-522.

    Google images Pediatric sudden cardiac arrest. Policy

    statement. Pediatrics Vol. 129 No. 4 April 1, 2012