the bright future of diagnostic imaging
TRANSCRIPT
The bright Future of Diagnostic Imaging
Paul SmitSenior Vice President Medical Systems
2Medical Systems
Overview
• The role of Imaging in healthcare
• State of the art
• Philips’ position
• New developments
3Medical Systems
AcuteAcuteCareCare
SystemSystem
Role of imaging in healthcare
Symptoms
Tests
Diagnostic Imaging
Treatment(Imaging)
Follow up(Imaging)
Cured or chronic
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Role of Diagnostic Imaging in Healthcare• Determine nature, location and size of disease in
patients with symptoms• Guide interventions• Monitor the progress of treatment
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Market for Imaging has shown consistent growthGrowth is driven by new applications, increasing accuracy and increasing speed
>1 Billion Imaging Procedures/Year worldwide (source: Medtech Insight)
On average, 2 out of every 5 Patient Visits involve an imaging procedure in USA (source: SG-2)
€bl
n
02468
10121416
1950 1960 1970 1980 1990 2000
Nuclear Medicine
Ultrasound
CT
MRI
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Medical Technology creates proven benefits • “New technologies often bring health
improvements and productivity benefits.”
• “Around 70% of the survival improvement in heart attack mortality is a result of changes in technology.”
Source: Technology Benefits based on Study by Cutler and McClellan
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….which translates into a healthier population
Source: NCHS
Heart DiseaseHeart Disease
Cancer
Cancer
US Life Expectancy at Birth1950-2000
65707580
1950 1960 1970 1980 1990 2000
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Overview
• The role of Imaging in healthcare
• State of the art
• Philips’ position
• New developments
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CardioVascular X-RayAverage price: € 1 mln
• Diagnosis of bloodvessels– Heart– Brain– Body
• Guides treatments of the cardiovascular system– Clot removal , e.g. dottering– Stent placement– Aneurysms repair– Arythmia repair
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Philips’ continuous improvements in Cardiovascular X-Ray
Detail visible 0.001 mm3
Measurement time 35 s
0.000,004 mm3
5 s
1999 2003
250xfiner details
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Zooming allows the cardiologist to enlarge the microscopic images to the desired size
Repairing arteries in the brain
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Philips’ continuous improvements in Computed Tomography, CTAverage price € 0.4 – 1 mln• Diagnosis of anatomy,
all body parts• Workhorse of Radiology• Continuously faster and
more accurate
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Diagnosing lung cancer
• Courtesy of Wiemker et al. Medica Mundi 2003
0
50
100
150
200
250
1999 2000 2001 2002 2003
seconds
35x faster in 5 years
Detail visible >5 mm
Measurement time 222 s
2 mm
6.4 s
1998 2003
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Philips’ continuous improvements in MRIAverage price : € 0.6 - 3 mln• Diagnosis of anatomy,
most body parts• Unique in imaging soft
tissue, such as the brainand nervous system
• Continuously faster and more accurate 12 seconds
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Detail visible 1 mm2
Scanning time 90 s
0.06 mm2
8 s
1998 2003
Analyzing the brain
15xfaster
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Philips’ continuous improvements in UltrasoundAverage price : € 50 – 300 k• Most cost-efficient imaging technology • Wide array of applications,
incl. cardiovascular• Anatomy of many parts of the body• Obstetrics/Gynecology
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Signal / noise 5
Procedure time 20 min.
25
5 min.
1998 2003
Live 3-Dimensional Ultrasound
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Nuclear Medicine
Average price : € 0.4 - 2 mln• Most sensitive technology• Gold standard to assess heart infarction• Gold standard to detect primary cancer
and metastases• Increasingly used for brain (infarction)
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Philips’ trackrecord of continuous improvements in Nuclear Medicine• GEMINI: worlds first and only
“open” Positron Emission Tomography (PET) – CT
• 3D registration of PET and CT data
• Two scans for the price of one • Much better localization and
identification of disease • Improved Radiation treatments
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And reduced the cost per patient
• Greater than 50% reduction in scanning time – 60 minute scans reduced to less
than 30 minutes– Enhanced image quality – True clinical flexibility
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…Continuous improvement in Performance,drives usage and creates new procedures
• X-Ray: repair of brain vessels• CT: screening for lung cancer,
cardiac CT, virtual colonoscopy• MR: whole body cardiovascular
scans, cardiac MR, orthopedics• US: Biopsy guidance,
mammography• CT-PET: cancer localization and
staging, monitoring of cancer treatment
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… No wonder Imaging Systems are widely recognized for their impact
• MR and CT are considered the most important innovations in healthcare of the last 20 years
Fuchs &, Sox Health Affairs 2001
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….Which drive continuous growth in Imaging
Threefold increase in this decade:- Aging population- New cancer, Cardio Vascular and Neuro applications- Growth of Image guided interventions - Molecular Imaging Development Imaging Procedures (World)
0
400
800
1200
1600
2000
2400
2800
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010
Pro
ce
du
res
(m
illio
n)
+5%
+7%
+13%
Source: SG-2, Philips
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Overview
• The role of Imaging in healthcare
• State of the art
• Philips’ position
• New developments
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Philips is leading in many imaging areas
# 1 in Cardiovascular X# 1 in Cardiovascular X--RayRay
# 1 in digital X# 1 in digital X--Ray and digital Ultrasound in Cardiovascular UltrasoundRay and digital Ultrasound in Cardiovascular Ultrasound
# 1 in Nuclear Medicine# 1 in Nuclear Medicine
# 1 to market with 16 slice CT# 1 to market with 16 slice CT
# 1 in high# 1 in high--field MRfield MR
# 1 in oncology simulation and planning# 1 in oncology simulation and planning
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Technology leadership: Re-use of Unique technology from Philips Research
XresTMextreme resolution
From MRI To X-RayTo Ultrasound
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Clinical Leadership through collaborative research: Virtual Colonoscopy with CT
Overview
Lesion Annotation& Reporting
Orthogonalreformats
Frontview
Up
Left
Down
Right
Rearview
Lesionmarker
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Clinical Leadership through collaborative research: Virtual Colonoscopy with CT
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• Fast and very sharp images
High Resolution: 0.04 mm3
Clinical Leadership through collaborative Research: Stunning details with MR
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More accurate US images can change the way patients are treated
Clinical Leadership through collaborative research : Ultrasound
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Overview
• The role of Imaging in healthcare
• State of the art
• Philips’ position
• New developments
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Fusing MRI and X-Ray for targeted drug delivery
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XMR-guided targeted drug delivery (FeRx in HCC)
Courtesy: UCSF
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Molecular Imaging
• Images the cells at work inside the living body
• Allows earlier detection and characterization of disease
• Early assessment of treatment
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Molecular Imaging: the key ingredients
Imaging Modalities Targeted Contrast Agents
Targeting Bio-molecule
Contrast Element, e.g Gd
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Speeding up time-to-market of new imaging procedures
Pre clinical CT Pre clinical PET
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Clinical areas
• Oncology• Cardiology• Neurodegenerative
diseases of the brain
Courtesy: S. Wickline et al. Washington University, St Louis, USA
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• As new micro arteries are developing....
MR: Seeing the tumor grow
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Summarizing
• Imaging has made a big impact on healthcareover the last decades
• Continuous Technology development for better and faster diagnosis while lowering costs
• Future is bright as true Molecular Imaging is coming in sight
