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    SEMINAR ON

    NATIONAL FILARIA CONTROL

    PROGRAMME

    (NFCP)

    PRESENTED BY

    ARUN.JV

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    INTRODUCTION

    Filariasis has been a major public health

    problem in India next only to malaria. The

    disease was recorded in India as early as 6th

    century B.C. by the famous Indian physician,

    Susruta in his book Susruta Samhita. In

    7thcentury A.D., Madhavakara described signs

    and symptoms of the disease in his treatiseMadhava Nidhana which hold good even

    today.

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    INTRODUCTION cont

    In 1709, Clarke called elephantoid legs in Cochin as

    Malabar legs.

    The discovery of microfilariae (MF) in the peripheral

    blood was made first by Lewis in 1872 in Calcutta(Kolkata).

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    FILARIASIS

    Filariasis is caused by several round, coiled and thread-

    like parasitic worms belonging to the family filaridea.

    These parasites after getting deposited on skin penetrate

    on their own or through the opening created by mosquitobites to reach the lymphatic system. The disease is caused

    by the nematode worm, either Wuchereria

    bancrofti orBrugia malayi and transmitted by ubiquitous

    mosquito species Culexquinquefasciatus and Mansonia annulifera/M.uniformisrespectively.

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    FILARIASIS

    Brugian filariasis

    Bancroftian filariasis

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    FILARIA VECTORS

    Culex quinquefasciatus transmits filariasis in

    India. Culex breeds in polluted water. Common

    breeding sites are wet pit latrines, septic tanks,barrow pits, cess pools, drains, disused wells,

    paddy fields, etc.

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    TRANSMISSION OF LYMPHATIC

    FILARIASIS

    The adult produces millions of very small

    immature larvae known as microfilariae, which

    circulate in the peripheral blood with markednocturnal periodicity. The worms usually live

    and produce microfilariae for 5-8 years.

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    In India, 99.4% of the cases are caused by the

    species - Wuchereria bancrofti whereas Brugia

    malayi is responsible for 0.6% of the problem.

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    Wuchereria bancrofti Brugia malayi

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    MAGNITUDE OF DISEASE

    Indigenous cases have been reported from about250 districts in 20 states/Union Territories.

    Cases of filariasis have been recorded from

    Andhra Pradesh, Assam, Bihar, Chhattisgarh, Goa,Jharkhand, Karnataka, Gujarat, Kerala, Madhya

    Pradesh, Maharashtra, Orissa, Tamil Nadu, Uttar

    Pradesh, West Bengal, Pondicherry, Andaman &

    Nicobar Islands, Daman & Diu, Dadra & NagarHaveli and Lakshadweep.

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    B. malayi is prevalent in the states of Kerala, Tamil Nadu, AndhraPradesh, Orissa, Madhya Pradesh, Assam and West Bengal.

    The single largest tract of this infection lies along the west coast of

    Kerala, comprising the districts of Trichur, Ernakulum, Alleppey,

    Quilon and Trivandrum, stretching over an area of 1800 sq km. Theinfection in the other six states is confined to a few villages. Surveys

    undertaken recently in Kerala and a few villages in other states revealed

    either a reduction of foci or complete elimination of the parasite as well

    as the vector(s) in many villages which were known to be endemic

    forB. malayi infection four decades back

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    ECONOMIC LOSS :

    About 1.2 billion man-days are lost due to

    filariasis every year leading to an economicloss of Rs. 3500 crore

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    NATIONAL FILARIA CONTROL

    PROGRAMME

    National filarial control programme was

    started in 1955.

    After pilot project in Orissa from 1949 to1954, the National Filaria Control Programme

    (NFCP) was launched in the country in 1955

    with the objective of delimiting the problem, to

    undertake control measures in endemic areas and

    to train personnel to manage the programme.

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    Pilot project in Orissa:

    mass drug administration with

    diethylcarbamazine (DEC)

    recurrent antilarval measures Residual insecticidal spray as anti-adult

    measure.

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    Recommendations of assessment

    committee.

    (a) proper environmental sanitation

    (b) antilarval measures by the application of oil.

    U d h NFCP h f ll i i i i b i

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    Under the NFCP the following avtivities are being

    undertaken

    Delimitation of the programme in unsurveyed

    areas.

    Adoption of antilarval and anti-mosquitomeasures.

    Detect and treat positive cases of filariasis.

    Install underground drainage system to preventmosquito breeding.

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    4 rural research cum training centres were

    established,one each in Andhra

    Pradesh,Maharashtra,Madhya Pradesh ,and in uttar

    Pradesh3 regional research cum training centres situated at

    Calicut ,Rajahamudry(AP) and Varanasi(UP) under the

    National Institute of communicable diseases ,Delhi.

    At the state level 12 headquarters bureaux arefunctioning.

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    National filarial control programme is being

    implemented through 206 filaria control units

    ,199 filaria clinics and 27 survey units primarilyin filarial endemic urban towns.In rural areas

    anti filarial medicines and morbidity

    management through primary health care system.

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    NATIONAL GOAL

    The National Health Policy 2002 aims

    at Elimination of LymphaticFilariasis by 2015.

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    The elimination is defined aslymphatic

    filariasis ceases to be public health problem,

    when the number of microfilaria carriers is lessthan 1 percent and the children born after

    initiation of ELF are free from circulating

    antigenaemia(presence of adult filarial worm inhuman body)

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    Central Assistance

    During Fourth Five Year Plan the NFCP was 100 per centcentrally sponsored programme. But in Fifth Five Year Plan,only material and equipment were supplied by the Centrefrom its share and the entire operational cost was borne bythe States.

    However, from 1978 onward the Central assistance wasfurther reduced by sharing the cost of material andequipment on 50:50 basis.

    Up to Seventh Five Year Plan the NFCP budget was separateand the same was merged with budget of Urban MalariaScheme during Eighth Five Year Plan continuing the sharingthe cost of material and equipment on 50:50 basis.

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    FILARIA CONTROL STRATERGY

    Vector control through anti larval operations

    Source reduction

    Detection and treatment of microfilariacarriers

    Morbidity management

    IEC

    i i d i l l

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    Anti-mosquito and anti-larval

    measures :

    Anti-larval measures with temephos in prescribed dosagein water storage tanks every week and application ofMineral larvidcidal oils on water surface are practiced.

    The larvicide under use includetemephos, Fenthion andMLO. The selection of breeding places for treatment with aparticular larvicide is done judiciously.

    Recurrent antilarval measures at weekly intervals.

    Environmental methods including source reduction byfilling ditches, pits, low lying areas, deweeding, desilting,

    etc. Biological control of mosquito breeding through larvivorous

    fish.

    Home based management of

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    Home based management of

    lymphedema cases and upscaling of

    hydrocele operations The line listing of lymphedema and hydrocelecases were initiated till 2004 by door to door

    survey in filarial endemic districts.Initiation

    has also been taken to demonstrate thesimple washing of foot to maintain hygiene for

    prevention of secondary bacterial and fungal

    infection in chronic lymph edema cases,sothat the patients get relief from frequent

    acute attacks.

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    Mass drug administration (MDA)

    DEC dosage schedule: The DEC dosage adopted

    in the programme is 6mg/kg body wt. per day

    for 12 days.

    The strategy for achieving the goal of eliminationis by Annual Mass Drug Administration of DEC for

    5 years or more to the population excluding

    children below two years, pregnant women andseriously ill persons in affected areas to interrupt

    transmission of disease.

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    During 2008 around 121 million population in

    selected districts of Tamil

    Nadu,Karnataka,Kerala and Andhra Pradesh

    were covered with co administration of singledose of DEC+Albendazole.Rest the districts

    were covered with DEC alone.The MDA

    coverage was 82.75% in 2007 and 85.9% in2008.

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    Objectives of MDA

    To review the progress of activities of singledose DEC mass administration in the selecteddistricts.

    To make independent assessment of theprogramme implementation with respect toprocess and outcome indicators.

    To recommend midcourse corrections andsuggest necessary steps for further course ofaction.

    Th B i P i i l f R i d

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    The Basic Principle of Revised

    Strategy for the Single Dose Mass DEC

    Administration

    Interruption of disease transmission

    Treatment of problems associated withlymphoedema (disability prevention and

    control)

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    One of the main reasons for "non-compliance"

    to the MDA programme is the occurrence of

    side-effects reported by consumers. DEC is

    reported to be safe, and does not produce anychronic toxicity.

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    Medicated salt regimens in India

    The DEC medicated salt project with 0.2%

    concentration was concluded at Karaikal;

    Pondicherry which gave significant reduction in

    microfilaraemia.

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    B.malayi control

    The pilot project under the auspices of NICD in

    Kerala has revealed that the vectors of

    B.malayi are amenable to indoor residual

    spray of HCH at a dose of 0.2 g/m2 per round,three rounds a year. Integrated vector control

    approach for control of this infection was

    being implemented by VCRC Pondicherry inCherthala of Alapuzhadistrict, Kerala.

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    National Filaria Control Programme in

    kerala

    Filariasis is prevalent in the entire coastal belt and insome pockets of Kerala. About 6.3 million people areexposed to the risk Filarisis and 2.8 million people areprotected by NFCP.The programme was launched in the State during1955-56. Now it is implemented through 16 NFCPunits, 2 Filaria Survey Units and the Filaria controlworks at Cherthala. Attached to the Filaria Units, 11Filaria clinics are functioning. The Filaria Survey Unit at

    Thrissur was shifted to Thiruvananthapuram in May 95and continues to function as main central unit atValiyathura in Thiruvananthapuram.

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    Activities

    Control Mosquito larvicidal spraying

    operation, pistia removal and anti parasitic

    (DEC) treatment.

    Assessment Entomological and parasitological

    (filaria survey)

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    Monitoring Agency

    The State Headquarters Bureau of Filariasis

    under the Assistant Director (Filaria) attached

    to the Directorate of Health Services is

    monitoring and assessing the work at theState level

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    Achievements of National Filaria Control

    Programme

    Year Persons Examined

    Cases detected

    Hydrocele Operations

    MF Disease

    200102 971658 13142 2374 1642

    2002

    03 1003222 13848 2527 2666

    200304 1055505 13292 1396 2287

    200405 1086526 10311 1776 4232

    2005

    06 1045770 8270 1024 3615

    20062007 925331 5588 623 3056

    20072008 1049923 4705 655 4250

    200809 up to May 194855 825 216 133

    A k h t d l th i i bj ti d

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    A workshop to develop the vision, objectives and

    strategies for the approach paper

    to the twelfth five year plan

    The filaria elimination strategies were also discussed.

    Kerala should aim to eliminate filariasis through activecase detection and

    through effective implementation of MDA campaign.

    Rehabilitation of patients including surgery andartificial aids should also be done effectively.

    An effective waste management and source reduction

    for mosquito is a necessary condition for reduction of incidence of communicable

    diseases.

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    Expected Community Participation

    Involvement of Panchayats in successful

    indoor residual insecticide spray is an essential

    aspect of the programme.

    Panchayats/villages/local bodies/villageheads/BDOs/MahilaMandals, religious groups

    etc. are to be informed about the spray

    schedule at least before a fortnight.

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    Role of NGOs

    Non Governmental Organizations (NGOs), CommunityBased Organisations (CBOs), Faith Based Organisations(FBOs) can play an important role in LF elimination.

    These organisations should be invited to discussions

    when the annual strategic plan is prepared, so thatthey can identify areas of interest for theirparticipation, which could be incorporated in thenational plan.

    A list of NGOs, DBOs, FBOs and enterprising Panchayatswith the possible areas of partnership should beprepared.

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    Mapping of areas through morbidity surveys.

    Social Mobilization for drug compliance.

    Supporting mass drug administration and

    management of adverse reactions.

    Morbidity Management at community level

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    MID-COURSE CORRECTIONS

    A geographically identified risk area or PHC should be madean intervention unit.

    Vector control should be a component in the LF eliminationcampaign. It is not wise to depend only on MDA.

    A single strip of two tablets, one each of DEC and Alb inblister pack could be used in the programme.

    Programme managers should be encouraged to adopt theprinciple of 'directly-observed treatment'.

    DEC-fortified salt and vector control as an adjunct should

    be introduced in all residual foci, including the areas whereother intervention measures are weak.

    An intensive information, education, communication andadvocacy campaign involving professional bodies is crucial.

    NURSES ROLE

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    NURSES ROLE

    Active detection of cases through surveys.the co-ordinated effort of peripheral level workers has to beensured.

    Supply of DEC tablets as per the government policiesand explaining the benefits.Removing the

    misconception of the people regarding adverse effectsof DEC is essential.

    Health education and promotion of IEC activities aboutthe disease,vector control,environmentalsanitation,removing social stigma of disease etc

    Ensuring adequate treatment for identified cases.

    Co-ordinating the efforts of NGOs and non voluntaryorganizations in filarial control activities.

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    CONCLUSION

    Elimination of filariasis using annual MDA is

    one of the most economical and beneficial

    disease control strategies undertaken so far in

    public health programmes. Now, the wholeworld is looking at the progress of the LF

    elimination programme in India as the

    population living at risk of infection is high,and hence the height of its achievement will

    greatly have a bearing at the global level.

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