programme booklet ebsa 2015ebsa.org/ebsa-2015/dokumente/ebsa2015_programmebooklet.pdf · 2015. 7....

Programme BookletEBSA 2015

www.ebsa2015.org

Biophysics in EuropeBiophysics in Europe

EBSA

10th EuropeanBiophysics CongressJuly 18 to 22, 2015 – Dresden, GermanyInternational Congress Center Dresden – ICCD

2 310th European Biophysics Congress July 18-22, 2015 | Dresden | Germany

4 Welcome Note of the Congress Organizers

6 Welcome Note of the EBSA President

8 Congress Organization

11 Sponsors and Partners

12 Exhibitors

14 Venue

15 Exhibition Plan

16 Poster Plan

18 Poster Presentation

19 Poster Awards

20 Instructions for Speakers

21 Plenary Lectures

Scientific Programme23 Saturday, July 18

24 Sunday, July 19

30 Monday, July 20

36 Tuesday, July 21

42 Wednesday, July 22

49 Industry Talks

50 Special Meetings

51 Social Programme

52 General Information

54 Dresden

55 Dresden City Map

Content


Dear Colleagues and Friends,

With great pleasure, and on behalf of the German Biophysical Society (DGfB, http://www.dgfb.org), we cordially welcome you to Dresden for the 10th European Biophysics Congress, EBSA 2015. We are delighted that biophysicists from over 28 European countries and 27 nations outside Europe will meet in Dresden, the ‘Venice at the Elbe River‘, in the upcoming days.

In addition to the biannual meeting of the DGfB, the European Biophysics Congress is one of the major events of the European biophysics community bringing together junior and senior scientists to stimulate discussions in all fields of biophysics ranging from molecular to cell biophysics.

The EBSA congresses and the EBSA journal, the European Biophysics Journal (EBJ), are the top priority activities of the European Biophysics Societies’ Association. All EBSA member societies were asked to suggest speakers, and the selection of the plenary speakers was overseen by an international scientific committee. Our symposia chairs suggested speakers and selected additional speakers from the over 800 abstracts we have received by March 16th, 2015. This selection procedure has led to a programme that we think is of high scientific level.

It is YOU – the speakers, those who contribute posters, and all who advance our knowledge in biophysics by active participation and discussions – who will shape the congress and make it a success. We are therefore particularly thankful to all speakers who accepted our invitation despite financial restrictions and economic trouble. Please do not forget to consider visiting the satellite meetings the congress was able to attract!

Reduced fees were offered to members of any biophysical society, and EBSA was able to sponsor 60 student bursaries to support participation of young scientists. In addition, the DGfB provided 8 travel grants for young scientists. We also gratefully acknowledge generous support by the US Biophysical Society, sponsoring a student poster competition, which underscores the excellent links between the societies.

Our thanks also go to the symposia chairs and the scientific committee, who did an outstanding job in selecting the very best. Special thanks to K.I.T. Group GmbH Dresden for their excellent and always highly professional service and organization, to Éric Quiniou for assembling the abstracts for the European Biophysics Journal Special Volume, to Springer for the ongoing pleasant collaboration, to Avanti Polar Lipids for supporting what has become a prize

Welcome Note of the Congress Organizers

with considerable reputation, and to the many sponsors, which you will find listed in this booklet. We particularly wish to express our thanks to Petra Kellers, who coordinated everything with great oversight, precision, efficiency, and commitment.

Many thanks, finally, to the Organizing Committee in Dresden; without their help and assistance, we would have sunk. The EBSA Executive Committee provided wonderful support over the past four years of preparation and valuable experience from previous congresses, with special thanks to Manuel Prieto, Manuela Pereira and, last but absolutely not least, Tony Watts for light speed help whenever needed.

We look forward to an exciting week in Dresden, the wonderful setting and culture, of which you hopefully will enjoy very much.

Lastly, we hope to see you again at the 11th EBSA / 19th IUPAB Congress inEdinburgh!

Claudia Steinem & Helmut Grubmüller

Congress Organization


Ladies and Gentlemen,Dear Colleagues,

On behalf of the Executive Committee of EBSA, the European Biophysical Societies’ Association, it is my pleasure and honor to welcome you to the 10th European Biophysics Congress in Dresden.

This Association of Biophysical Societies (EBSA) is today a very active organization, encompassing 31 countries across Europe and extending into Asia and North Africa. The biennial congresses are the flagship of EBSA, and they have become large events, with typically more than 1000 participants, coming not only from the member countries, but also from many other nations. In addition to its main congress, EBSA is also very active in supporting other meetings in Europe, in providing grants for students to visit other laboratories, and in organizing and sponsoring Biophysics Summer Schools. 60 Bursaries were awarded to students to attend this EBSA Congress in Dresden. We would like to invite you all to become closely involved with EBSA. Please bring this information to the attention of your colleagues in your home laboratories, and if there is no significant organized activity around biophysics in your country, do contact us at this meeting to see how we can help – another achievement of EBSA is in helping establish new or incorporate national societies into EBSA. If there is already an active society in your country, we encourage you to join and become active within it and to ensure that EBSA activities and funding opportunities for students are on the agenda for committee meetings. Furthermore, please visit our website (http://www.ebsa.org), subscribe to our regular email list of ‘News associated with biophysics’, and do not hesitate to attend our general assembly during this congress, even if you are not the voting representative of your country.

Biophysics is a multidisciplinary subject at the frontier of science, spanning biology, physics and chemistry, and encompassing many other subjects. We should be proud of being scientists in this area, and we should attract to biophysics researchers who are within this broad definition. It is also our duty to flag up biophysics as a critical area of science, and to press for recognition of its relevance, in order that it becomes well supported at the European level. EBSA is an active contributor to ISE (Initiative for Science in Europe) and IUPAB on your behalf, and is recognizing the newly formed Association of Resources for Biophysical Research in Europe (ARBRE) at this congress. This involvement can only be achieved if we succeed in getting greater visibility for biophysics.

The internationally-recognized ‘EBSA Young Investigator’s Award’, and the ‘Avanti Polar Lipids/EBSA Award’ in recognition of outstanding contributions to lipid and membrane biophysics, will be special moments within our

Welcome Note of the EBSA President

congress, with plenary lectures given by both awardees, Dr. Iva Tolić and Professor Antoinette Killian, respectively. For both awards, a significant number of excellent nominations were received, in line with the high quality of biophysics research in Europe.

I would like to mention the EBSA Journal, the ‘European Biophysics Journal’, and thank Anthony Watts, the Managing Editor, and his board of editors for their excellent work. The journal deserves your close attention, since it is the main source of revenue for EBSA through Springer, which allows us, among many other activities, to provide significant support for the EBSA congresses.

On behalf of the EBSA Executive Committee, and also on behalf of all participants, I would like to thank the Organizing Committee of this EBSA congress, and specifically Helmut Grubmüller and Petra Kellers. This is going to be an excellent scientific event, and they and their team have worked incredibly hard in its organization.

Finally, I would like to inform you that this congress is a special moment in the Association’s history, since we are celebrating EBSA’s 30th anniversary! Early 1984 saw the emergence of the European Biophysics Journal (EBJ), the EBSA logo also dates from 1984, and at a meeting in Bristol, the EBSA general assembly witnessed the attendance of 8 adhering member societies. We have now grown to about 33 national society members, and we have plenty of reasons to celebrate EBSA – Biophysics in Europe.

Looking forward to seeing you all in Edinburgh in July 2017 at the 11th EBSA Congress, which will be held jointly with IUPAB and will be organized together with the British Biophysical Society and the UK Institute of Physics.

Manuel Prieto President of EBSA



Organizing CommitteeCongress ChairHelmut Grubmüller Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

German Biophysical Society (DGfB) ChairClaudia Steinem University of Göttingen, Germany

EBSA Executive CommitteeChair Manuel Prieto Centro Química-Física Molecular, Lisbon, Portugal

Scientific CommitteeChair Hermann Gaub Ludwig Maximilian University Munich, Germany

MembersJudith ArmitageUniversity of Oxford, United KingdomErnst BambergMax Planck Institute for Biophysics, Frankfurt, GermanyPatricia BassereauInstitut Curie, Paris, FranceNynke Dekker Delft University of Technology, The NetherlandsAlberto Diaspro Istituto Italiano di Tecnologia, Genua, ItalyHans-Joachim GallaUniversity of Münster, GermanyAna Garcia-Saez Max Planck Institute for Intelligent Systems, Tübingen, GermanyChristian GriesingerMax Planck Institute for Biophysical Chemistry, Göttingen, GermanyStephan GrillBiotechnology Center, TU Dresden, GermanyHelmut Grubmüller Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

Thomas Gutsmann Research Center Borstel, Leibnitz Association, GermanyStefan HellMax Planck Institute for Biophysical Chemistry, Göttingen, GermanyJean-François Joanny Institut Curie, Paris, FranceWolfgang JungeUniversity of Osnabrück, GermanySarah KösterUniversity of Göttingen, GermanyBerenike MaierUniversity of Cologne, GermanyErwin NeherMax Planck Institute for Biophysical Chemistry, Göttingen, GermanyBen SchulerUniversity of Zurich, SwitzerlandPetra SchwilleMax Planck Institute of Biochemistry, Martinsried, GermanyClaudia SteinemUniversity of Göttingen, Germany

MembersJosé L. Carrascosa Centro Nacional de Biotecnología (CSIC), Madrid, SpainHelmut GrubmüllerMPI for Biophysical Chemistry, Göttingen, GermanyAndré MatagneCentre for Protein Engineering, Liege, BelgiumLászló MátyusUniversity of Debrecen, HungaryPavol MiškovskýP. J. Šafárik University, Košice, Slovakia

Manuela M. PereiraUniversidade Nova de Lisboa, Oeiras, PortugalCatherine A. Royer Rensselaer Polytechnic Institute, Troy, NY, USAJohn M. SeddonImperial College London, UKIlpo VattulainenTampere University of Technology, Finland Anthony Watts Biochemistry Department, University of Oxford, UKAnthony J. WilkinsonStructural Biology Laboratory, University of York, UK


EBSA



Local Organizing CommitteeChair Stephan Grill Biotechnology Center, Technical University Dresden, Germany

Cost SymposiaWe gratefully acknowledge the organization of the COST Symposia Understanding Movement and Mechanism in Molecular Machines and Biophysics of GPCRs by the COST Association Actions CMST Action CM1306 and GLISTEN - Action CM1207.

MembersStefan Diez B Cube, Technical University Dresden, GermanyHans-Joachim GallaUniversity of Münster, GermanyHelmut GrubmüllerMax Planck Institute for Biophysical Chemistry, Göttingen, GermanyJochen GuckBiotechnology Center, Technical University Dresden, GermanyFrank JülicherMax Planck Institute for the Physics of Complex Systems, Dresden, Germany

Anne MeyerLeibnitz Institute for Solid State and Materials Research, Dresden, GermanyDaniel MüllerSwiss Federal Institute of Technology Zurich (ETH), SwitzerlandOliver SchmidtLeibnitz Institute for Solid State and Materials Research, Dresden, GermanyPetra SchwilleMax Planck Institute of Biochemistry, Martinsried, GermanyKai SimonsMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

Sponsors and Partners

* Declaration in accordance with FSA code of transparency (Association for Voluntary Self-Regulation in the pharmaceutical industry): Boehringer Ingelheim Pharma GmbH & Co. KG provided € 300.00 for the sponsorship item „Logo & Link“

*


Exhibitors

Cenibra GmbHGroße Straße 1749565 Bramsche

Germany

T +49 5461 880920F +49 5461 880930M +49 171 4741069

[email protected]

Dr. Christoph EnzManaging Director


TerraceMain entrance

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EBSA 2015

Venue Exhibition Plan

The International Congress Center Dresden (ICCD) and the adjoining Maritim hotel are located on the banks of the river Elbe in the heart of Dresden. The congress center is one of the most modern conference centers in Europe and displays a unique architecture inspired by the slope of the river Elbe.

Venue Address:Maritim Hotel & International Congress Center Dresden – ICCD Ostra-Ufer 2 01067 Dresden, Germany

Lectures will be held in 3 halls located on the same floor: Plenary Hall, Hall 1 and Hall 2. The Poster presentation will be set up in the Exhibition Area and the Foyer. Catering will be provided in the Exhibition Area as well as in the Foyer.

The congress dinner will be held on the terrace level of the ICCD giving you the opportunity to enjoy the unique panoramic view of the river valley and the historic city center.

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Exhibitors

1 LUMICKS B.V. 2 Hamamatsu Photonics Deutschland GmbH 3 New England Biolabs GmbH 4 Mad City Labs GmbH 5 Springer-Verlag GmbH 6 Avanti Polar Lipids, Inc. 7 Nikon GmbH 8 Cambridge University Press 9 IOP Publishing 10 Molecular Devices Ltd. 11 PIEZOCONCEPT 12 Luigs & Neumann Feinmechanik und Elektrotechnik GmbH 13 Bio-Logic SAS 14 Dynamic Biosensors GmbH 15 AHF analysentechnik AG 16 Applied Photophysics Ltd. 17 Malvern Instruments Ltd 18 JPK Instruments AG 19 Cobolt AB / von Gegerfelt PHOTONICS 20 Taylor & Francis / CRC Press 21 LOT-Quantum Design GmbH 22 Visitron Systems GmbH 23 PicoQuant GmbH 24 Gesellschaft für Silizium- Mikrosysteme (GeSiM) mbH 25 Anton Paar Germany GmbH 26 TOPTICA Photonics AG 27 Nanion Technologies GmbH 28 Cenibra GmbH 29 HEKA Elektronik Dr. Schulze


S01 Protein Structure and FunctionS02 Synthetic Biology and NanobiophysicsS03 Live Imaging and Optical MicroscopyS04 Photobiophysics, Biological Electron and Proton TransferS05 Molecular MotorsS06 Supramolecular Assemblies and AggregationS07 Membrane Structure and DomainsS08 Single Molecule BiophysicsS09 Material Science in BiophysicsS10 Protein-Nucleic Acid InteractionsS11 New Methods for Computational BiophysicsS12 Biospectroscopy, EPR and NMR

S13 Biomolecular Simulation and Computational BiophysicsS14 Systems Biology and Multi-Cellular SystemsS15 Biologically Active PeptidesS16 Membranes and VesiclesS18 Protein Folding, Assembly and StabilityS19 Channels and TransportersS20 Cell Biophysics and SignalingS21 Intrinsically Disordered ProteinsS22 Protein-Lipid InteractionsS23 Molecular RecognitionS24 NeurosciencesLate Late Posters – Diverse Topics

LateLate

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S24 S24

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Hall 2 Hall 1 Plenary Hall

Poster Plan


Poster Awards

All regular posters and short talk posters will be on display from Sunday, July 19 to Wednesday, July 22.

Authors are kindly requested to be present at their posters from 13:00 to 14:30 on the following days:Odd poster numbers: Sunday, July 19 and Tuesday, July 21Even poster numbers: Monday, July 20 and Wednesday, July 22

Posters should be mounted on Sunday, July 19 before the beginning of the lunch break / poster session at 12:20. Posters should be removed on Wednesday, July 22 until 16:30. Remaining posters will be discarded by the organizer.

Late posters will be on display during two separate sessions.Authors of late posters are kindly requested to be present at their posters from 13:00 to 14:30 on all respective days of their Late Poster Session.

Late Poster Session 1: Topics S01 - S09on Sunday, July 19 and Monday, July 20

Posters should be mounted on Sunday, July 19 before the beginning of the lunch break / poster session at 12:20. Posters should be removed on Monday, July 20 until 16:30. Remaining posters will be discarded by the organizer.

Late Poster Session 2: Topics S10 - S24on Tuesday, July 21 and Wednesday, July 22

Posters should be mounted on Tuesday, July 21 before the beginning of the lunch break / poster session at 12:20. Posters should be removed on Wednesday, July 22 until 16:30. Remaining posters will be discarded by the organizer.

Please see previous pages for poster plan.

The Biophysical Society is proud to continue its tradition of sponsoring a student poster competition at the EBSA congress. All students presenting their research at EBSA 2015 will be evaluated during the poster sessions by members of the selection committee. Twelve $500 awards will be presented.

FEBS Journal publishes papers in all areas within the Molecular, Cellular and Biochemical Sciences. It supports young scientists with FEBS Journal Poster Prizes, which are awarded by journal editors at key conferences throughout the year. The FEBS Journal is pleased to award two poster prizes of €200 at EBSA 2015.

Biomedical Physics and Engineering Express – a new express journal from IOP Publishing – will present 4 x €100 poster awards to young scientists presenting high quality interdisciplinary research at the EBSA 2015 Congress. BPEX is a broad, inclusive, rapid review journal devoted to publishing new research in all areas of biomedical engineering, biophysics and medical physics. The journal has a special emphasis on interdisciplinary work between these fields.

All poster prizes will be awarded during the Closing Ceremony on Wednesday, July 22.

Poster Presentation


Gunnar von Heijne

Department of Biochemis-try and Biophysics, Stockholm University, Sweden

Saturday, July 18 17:15-18:00

“A biophysical perspective on co-translational protein translocation, membrane insertion and folding”

Chair: Helmut Grubmüller, Germany

Iva M. Tolić

Division of Molecular Biology,Ruđer Bošković Institute,Zagreb, Croatia

Sunday, July 19 09:00-09:45

EBSA Young Investigators’ Medal and Prize“Forces in the mitotic spindle”

Chair: Manuel Prieto, Portugal

Matthias Rief

Department of Physics, Technical University, Munich, Germany

Sunday, July 19 14:45-15:30

„Mechanics of single protein molecules”

Chair: André Matagne, Belgium

Martin Fussenegger

Department of Biosystems Science and Engineering, Swiss Federal Institute of Technology (ETH), Zurich, Switzerland

Monday, July 20 09:00-09:45

“Metabolic prostheses – synthetic biology-inspired treatment strategies for metabolic disorders”

Chair: Lázló Mátyus, Hungary

Angela M. Gronenborn

Department of Structural Biology, University of Pittsburgh, United States

Monday, July 20 14:45-15:30

“An ingenious cloak for subterfuge – the HIV capsid structure”

Chair: Christian Griesinger, Germany

Instructions for Speakers Plenary Lectures

Presentation time:Plenary talks - Speaking time is 45 minutes.Invited talks - Speaking time is 20 minutes plus 5 minutes discussion.COST talks - Speaking time is 15 minutes plus 5 minutes discussion.Short talks - Speaking time is 10 minutes plus 5 minutes discussion.

Speakers room / Media Check The Media Check is located in a separate room next to the registration desk in the foyer of the hall level. Technical support staff will be present to assist speakers in uploading their pres entations. Furthermore, the speakers can review their presentations and can im plement last-minute changes, if required.

Opening hours: Sunday, July 18 14:30 - 18:00 Saturday, July 19 - Wednesday, July 22 08:00 - 18:30

Presentation upload:The EBSA 2015 Congress Team will use a centralized management system for all presentations and will provide laptops in all lecture halls. We would very much appreciate if you could make use of these laptops to minimize delays and to avoid technical interruptions. Technical staff is permanently available in the Media Check to assist you.

For using the centralized presentation management system, all presentations need to be transferred to this system before the beginning of each session. Therefore, all speakers are requested to upload them on-site at the Media Check at least 2 hours before the beginning of their session or the day before, if possible.

All presentations need to be submitted to the Media Check via CD ROM (CD-R/RW), DVD-ROM (DVD-R/RW) or USB memory stick. All files associated with one presentation (PowerPoint file, movie files etc.) should be saved to the same folder/location. We recommend saving videos and graphics/pictures separately on a storage medium - in case of problems, the originals can be re-inserted on-site at the Media Check.

Speakers using MacBooks and/or the Keynote presentation software are kindly requested to export their presentation to the PowerPoint format. In case of problems, the Media Check staff will be glad to assist you in converting your files to the requested format.

Speakers using their own laptop are kindly asked to proceed to the Media Check at least 2 hours before the beginning of their session or the day before in order to clarify the technical prerequisites with the technicians and to coordinate the processes involved.


Saturday, July 18

Plenary Hall

Plenary Hall

Exhibition

16:30 – 17:00 WELCOME ADDRESS

PLENARY LECTURE Chair: Helmut Grubmüller, Germany

17:15 – 18:00 Gunnar von Heijne, Stockholm, Sweden (O-1)A biophysical perspective on co-translational protein translocation, membrane insertion and folding

18:00 – 19:00 WELCOME RECEPTION

Plenary Hall

Plenary Hall

Exhibition Area

Plenary Lectures

J. Antoinette Killian

Department of Chemistry, Membrane Biochemistry and Biophysics Group,Utrecht University,The Netherlands

Tuesday, July 21 09:00-09:45

Avanti Polar Lipids / EBSA Award “Studying lipid/protein interactions: from self-assembled model membranes to native nanodiscs”

Chair: Anthony Watts, United Kingdom

Raymond E. Goldstein

Department of Applied Mathematics and Theoretical Physics, University of Cambridge, United Kingdom

Tuesday, July 21 14:45-15:30

“Synchronization of eukaryotic flagella”

Chair: Ilpo Vattulainen, Finland

Christian Eggeling

Weatherall Institute of Molecular Medicine,Investigative Medicine Division, Nano-Immunology Group, University of Oxford, United Kingdom

Wednesday, July 22 09:00-09:45

“Advanced optical microscopy for deeper insights into membrane bioactivity”

Chair: Manuel Prieto, Portugal

Marileen Dogterom

Department of Bionanoscience, Technical University Delft, The Netherlands

Wednesday, July 22 14:45-15:30

“Minimal systems for the study of microtubule-based cell polarity in fission yeast”

Chair: Stefan Diez, Germany

SCIENTIFIC PROGRAMME


EBSA


Sunday, July 19

PLENARY LECTURE Chair: Manuel Prieto, Portugal

09:00 – 09:45 Iva M. Tolić, Zagreb, Croatia (O-2)Forces in the mitotic spindle EBSA Young Investigators‘ Medal and Prize

1. PROTEIN STRUCTURE AND FUNCTION Chairs: Stefan Raunser, Germany & Angela M. Gronenborn, United States

09:50 – 10:15 Vinothkumar Kutti Ragunath, Cambridge, United Kingdom (O-14)Single particle electron cryo microscopy of membrane proteins

10:15 – 10:40 Sebastian Hiller, Basel, Switzerland (O-15)Molecular mechanisms in outer membrane protein biogenesis

10:40 – 11:10 Coffee Break

11:10 – 11:35 Ilme Schlichting, Heidelberg, Germany (O-16)Protein structure and dynamics using X-ray free-electron lasers

11:35 – 11:50 Sophie Zinn-Justin, Gif-sur-Yvette, France (O-17)Tailed bacteriophage architecture from a combination of liquid & solid state NMR and EM data

11:50 – 12:05 Daniel Boehringer, Zurich, Switzerland (O-18)Cryo-EM structure of the 55S mammalian mitochondrial ribosome

12:05 – 12:20 Pascal Damian Odermatt, Lausanne, Switzerland (O-19)Correlated atomic force microscopy and single molecule localization microscopy

PARALLEL SESSIONS

Plenary Hall

2. SYNTHETIC BIOLOGY AND NANOBIOPHYSICSChairs: Petra Schwille, Germany & Hagan Bayley, United Kingdom

09:50 – 10:15 Roy Bar-Ziv, Rehovot, Israel (O- 92)Programmable on-chip DNA compartments as “artificial cells”

10:15 – 10:40 Damien Baigl, Paris, France (O-93)Soft and triggerable synthetic biological systems: from DNA to enzymes and membrane proteins


11:10 – 11:35 Tobias J. Erb, Marburg, Germany (O-94)We do it our (path)way: Using biochemistry and synthetic biology to establish synthetic C02-fixation

11:35 – 11:50 Andrew J. Turberfield, Oxford, United Kingdom (O-95)Folding pathways: DNA origami as a model system

11:50 – 12:05 Moritz Kreysing, Dresden, Germany (O-96)The value of a binary fitness landscape for the origin of molecular life

12:05 – 12:20 Mark Howarth, Oxford, United Kingdom (O-97)Molecular team-building using a family of protein- superglues enables programmable cell triggering

Hall 1Plenary Hall


Sunday, July 19

3. LIVE IMAGING AND OPTICAL MICROSCOPYChairs: Jörg Langowski, Germany & Elina M. lkonen, Finland

09:50 – 10:15 Melike Lakadamyali, Barcelona, Spain (O-113)Super-resolution imaging of nucleosome organization

10:15 – 10:40 Silvio O. Rizzoli, Göttingen, Germany (O-114)Quantitative imaging of membranes and synapses


11:10 – 11:35 Peter Jomo Walla, Braunschweig, Germany (O-115)3D-polarization of fluorescence markers determined by a wide field double-modulation approach

11:35 – 11:50 Georg E. Fantner, Lausanne, Switzerland (O-116)Timing the process of bacterial division with nm spatial and ms temporal precision

11:50 – 12:05 Maximilian H. Ulbrich, Freiburg, Germany (O-117)Dissecting subunit assembly by single molecule imaging of membrane protein complexes

12:05 – 12:20 Jorge Bernardino de la Serna, Oxford, United Kingdom (O-118)Advanced microscopy studies of the true resting state of T-cells

12:20 – 14:45 Lunch, Posters & ExhibitsRegular posters: odd poster numbersLate posters: topics S01 - S09please see page 16 for poster plan

Industry Talks13:00 - 13:30 | Applied Photophysics Ltd.14:00 - 14:30 | Nanion Technologies GmbHplease see page 49 for additional information

Hall 2

Hall 2

PLENARY LECTURE Chair: André Matagne, Belgium

14:45 – 15:30

Matthias Rief, Munich, Germany (O-3)Mechanics of single protein molecules

NEW AND NOTABLE Chair: Helmut Grubmüller, Germany

15:30 – 15:55

Karl Duderstadt, Groningen, The Netherlands (O-10)Single replication machines at work: the coordination of daughter strand synthesis


Plenary Hall

Plenary Hall

4. PHOTOBIOPHYSICS AND BIOLOGICAL ELECTRON AND PROTON TRANSFER Chairs: Klaus Gerwert, Germany & Pavol Miškovský, Slovakia

16:25 – 16:50

Hideki Kandori, Aichi, Japan (O-159)Molecular mechanism of ion-transporting microbial rhodopsins

16:50 – 17:15 G. Ulrich Nienhaus, Karlsruhe, Germany (O-160)Chromophore photophysics and dynamics in fluorescent proteins of the GFP family

17:15 – 17:25 Break

17:25 – 17:50 Marián Fabian, Košice, Slovakia (O-161)Ferryl intermediates of heme-copper oxidases

PARALLEL SESSIONS

Plenary Hall


Sunday, July 19

17:50 – 18:05 Juan A. Bueren-Calabuig, Dundee, United Kingdom (O-162)Elucidating the proton transfer mechanism of the respiratory complex I using molecular dynamics

18:05 – 18:20 Petra Hellwig, Strasbourg, France (O-163)Coupling of H+/e- transfer in proteins from respiration studied by electrochemistry and SEIRAS

18:20 – 18:35 Jens Kuhne, Bochum, Germany (O-164)Infrared Spectroscopy on Channelrhodopsin-2 reveals ultrafast deprotonation of E90

5. MOLECULAR MOTORSChairs: Stefan Diez, Germany & Iva M. Tolić, Croatia

16:25 – 16:50 E. Michael Ostap, Philadelphia, United States (O-187)Structural determinants of myosin mechanosensing

16:50 – 17:15 Nenad Pavin, Zagreb, Croatia (O-188)Pivoting of microtubules facilitates formation of microtubule bundles and kinetochore capture

17:15 – 17:25 Break

17:25 – 17:50 Vincent Croquette, Paris, France (O-189)DNA and RNA helicase single molecule assays

17:50 – 18:05 Arne Gennerich, New York, United States (O-190)Structure-dependent force generation and stepping of cytoplasmic dynein

18:05 – 18:20 Andrej Vilfan, Ljubljana, Slovenia (O-191)The working stroke of the kinesin-14, ncd, comprises at least two substeps of different direction

18:20 – 18:35 Borja Ibarra, Madrid, Spain (O-192)haracterization of the translocation mechanism of a replicative DNA polymerase

Hall 1

6. SUPRAMOLECULAR ASSEMBLIES AND AGGREGATIONChairs: Daniel Huster, Germany & José Carrascosa, Spain

16:25 – 16:50 Tuomas P. J. Knowles, Cambridge, United Kingdom (O-211)Kinetics of protein aggregation

16:50 – 17:15 Jaime Martín-Benito, Madrid, Spain (O-212)Influenza virus nucleocapsid polymorphism determined by cryo-electron microscopy

17:15 – 17:25 Break

17:25 – 17:50 Torleif Härd, Uppsala, Sweden (O-213)Solid-state NMR and molecular modeling provide structural information on amyloid-β protofibrils

17:50 – 18:05 Bernhard Schuster, Vienna, Austria (O-214)Biomimetic S-layer – lipid self-assemblies as platform for membrane-active peptides and proteins

18:05 – 18:20 Aurélien L. Furlan, Amiens, France (O-215)Self-assemblies of a new amphiphilic cyclodextrins and their interactions with model membranes

18:20 – 18:35 Alex I. M. van der Wateren, Cambridge, United Kingdom (O-216)Thioflavin-T: application for α-synuclein aggregation kinetics

19:00 – 20:00 Optional: City Tour Dresden(see page 51 for details)

Hall 2

Main Entrance Congress Center


Monday, July 20

PLENARY LECTURE Chair: László Mátyus, Hungary

09:00 – 09:45 Martin Fussenegger, Zurich, Switzerland (O-4)Metabolic prostheses – synthetic biology-inspired treatment strategies for metabolic disorders

7. MEMBRANE STRUCTURE AND DOMAINSChairs: Claudia Steinem, Germany & John M. Seddon, United Kingdom

09:50 – 10:15 Kai Simons, Dresden, Germany (O-244)From lipid rafts to bacterial membranes

10:15 – 10:40 Maikel C. Rheinstädter, Ontario, Canada (O-245)Frontiers in membrane biophysics


11:10 – 11:35 Rumiana Dimova, Potsdam, Germany (O-246)Phase separation in ternary mixture membranes: effect of adhesion and protein adsorption

11:35 – 11:50 Michael Dent, London, United Kingdom (O-247)Imaging patterns in lipid membranes through the use of molecular rotors

11:50 – 12:05 Jannik Larsen, Copenhagen, Denmark (O-248)Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases

12:05 – 12:20 Pierre-Emmanuel Milhiet, Montpellier, France (O-249)Structure and dynamics of membrane lipid nanodomains using high-speed atomic force microscopy

PARALLEL SESSIONS

Plenary Hall

8. SINGLE MOLECULE BIOPHYSICSChairs: Daniel Müller, Germany & Thomas Schmidt, The Netherlands

09:50 – 10:15 David Alsteens, Basel, Switzerland (O-302)Mapping and quantifying individual interactions using FD curves based AFM

10:15 – 10:40 Lene Oddershede, Copenhagen, Denmark (O-303)DNA supercoiling sharpens an epigenetic switch


11:10 – 11:35 Carsten Grashoff, Martinsried, Germany (O-304)Second-generation biosensors to measure piconewton forces in cells

11:35 – 11:50 Mathilde A. Bercy, Paris, France (O-305)Optical trapping reveals that the dynamics of hairpins is closer to equilibrium for DNA than for RNA

11:50 – 12:05 Katia Cosentino, Tübingen, Germany (O-306)Single molecule approach to study membrane pore formation by Bcl-2 proteins

12:05 – 12:20 Michael A. Nash, Munich, Germany (O-307)Analyzing force propagation through an ultrastable protein complex with experiments and simulation

Hall 1Plenary Hall


9. MATERIAL SCIENCE IN BIOPHYSICSChairs: Anne K. Meyer, Germany & Erik Reimhult, Austria

09:50 – 10:15 Robert Horvath, Budapest, Hungary (O-343)Label-free optical waveguide biosensors: novel configurations and biophysical applications

10:15 – 10:40 Michael Elbaum, Rehovot, Israel (O-344)Quantitative 3D cellular imaging by cryo-scanning transmission electron tomography (CSTET)


11:10 – 11:35 Valentina Benfenati, Bologna, Italy (O-345)Organic biofunctional materials and device to study neurons and astrocytes electrophysiology

11:35 – 11:50 Gustav Emilsson, Göteborg, Sweden (O-346)Polymer functionalization of gold surfaces for use in biointerface science

11:50 – 12:05 Leon J. Juarez-Hernandez, Trento, Italy (O-347)Biosystems interfaced to memristors: Early evidences to study neuromorphic architectures

12:05 – 12:20 Rok Podlipec, Ljubljana, Slovenia (O-348)Scaffold biocompatibility with respect to biopolymer mobility and cell adhesion dynamics

12:20 – 14:45 Lunch, Posters & ExhibitsRegular posters: even poster numbersLate posters: topics S01 - S09please see page 16 for poster plan

Industry Talks13:00 - 13:30 | Malvern Instruments Ltd.14:00 - 14:30 | Mad City Labs GmbHplease see page 49 for additional information

Hall 2 PLENARY LECTURE Chair: Christian Griesinger, Germany

14:45 – 15:30

Angela M. Gronenborn, Pittsburgh, United States (O-5)An ingenious cloak for subterfuge – the HIV capsid structure

NEW AND NOTABLE Chair: José Carrascosa, Spain

15:30 – 15:55

Janine D. Brunner, Zurich, Switzerland (O-11)Principles of lipid scrambling: Structural insights from a TMEM16 family member


Plenary Hall

Plenary Hall

10. PROTEIN-NUCLEIC ACID INTERACTIONS Chairs: Ulrich Nienhaus, Germany & Anthony J. Wilkinson, United Kingdom

16:25 – 16:50

Marina V. Rodnina, Göttingen, Germany (O-362)Co-translation folding of proteins in and out of the ribosome exit tunnel

16:50 – 17:15 Fernando Moreno Herrero, Madrid, Spain (O-363)Condensation of DNA by the bacterial centromere binding protein Spo0J/ParB

17:15 – 17:25 Break

17:25 – 17:50 Marcelo Nollmann, Montpellier, France (O-364)3D folding mechanisms of bacterial chromosomes

17:50 – 18:05 Beat Fierz, Lausanne, Switzerland (O-365)Single-molecule chromatin dynamics: HP1a multivalency governs heterochromatin assembly

PARALLEL SESSIONS

Plenary Hall

Monday, July 20

Hall 2


18:05 – 18:20 Dagmar Klostermeier, Münster, Germany (O-366)A novel mechanism of negative supercoiling by DNA gyrase without double-strand breaks

18:20 – 18:35 Anton A. Polyansky, Vienna, Austria (O-367)Deciphering the physicochemical determinants of mRNA-driven localization of proteins

11. NEW METHODS FOR COMPUTATIONAL BIOPHYSICSChairs: Gerhard Hummer, Germany & Ilpo Vattulainen, Finland

16:25 – 16:50 Christine Peter, Konstanz, Germany (O-386)Biomolecular simulation on multiple scales: approaches and challenges

16:50 – 17:15 Frank Noé, Berlin, Germany (O-387)Simulating rare events in molecular dynamics simulations using reversible Markov models

17:15 – 17:25 Break

17:25 – 17:50 Francesco Gervasio, London, United Kingdom (L-786)Investigating allosteric regulation through enhanced sampling simulations

17:50 – 18:05 Viveca Lindahl, Solna, Sweden (O-389)Sampling rare biomolecular events with adaptive pulling simulations

18:05 – 18:20 R. Thomas Ullmann, Göttingen, Germany (O-390)GromEx: Electrostatics with chemical variability for realistic molecular simulations on the exascale

18:20 – 18:35 Samuel Genheden, Southampton, United Kingdom (O-391)An all-atom/coarse-grained hybrid approach to study membrane processes

Hall 1

12. BIOSPECTROSCOPY, EPR AND NMRChairs: Christian Griesinger, Germany & Martin Blackledge, France

16:25 – 16:50 Daniella Goldfarb, Rehovot, Israel (O-414)Tracking conformations of proteins by Gd3+ distance measurements: from in-vitro to in-cell

16:50 – 17:15 Adam Lange, Berlin, Germany (O-415)Hybrid NMR and EM models of bacterial supramolecular protein assemblies

17:15 – 17:25 Break

17:25 – 17:50 Remco Sprangers, Tübingen, Germany (O-416)NMR spectroscopy of large complexes: correlating protein motions with function

17:50 – 18:05 Daniel Klose, Zurich, Switzerland (O-417)Light-induced switching of HAMP domain conformation and dynamics by time-resolved EPR spectroscopy

18:05 – 18:20 Denise Schuetz, Frankfurt, Germany (O-418)Conformational flexibility of POTRA domains from cyanobacterial Omp85 studied by PELDOR spectroscopy

18:20 – 18:35 Anna Weyrauch, Halle (Saale), Germany (O-419)EPR- and IRRAS studies on α-Synuclein

19:00 – 20:00 EBSA General Assembly (see page 50 for details)

Hall 2

Plenary Hall

Monday, July 20


Tuesday, July 21

PLENARY LECTURE Chair: Anthony Watts, United Kingdom

09:00 – 09:45 J. Antoinette Killian, Utrecht, The Netherlands (O-6)Studying lipid/protein interactions: from self-assembled model membranes to native nanodiscs EBSA Young Investigators‘ Medal and Prize

13. BIOMOLECULAR SIMULATION AND COMPUTATIONAL BIOPHYSICSChairs: Helmut Grubmüller, Germany & Esteban Vöhringer-Martinez, Chile

09:50 – 10:15 Stefano Piana, New York, United States (O-450)The modelling of water dispersion and the properties of disordered protein states in simulation

10:15 – 10:40 Gerhard Hummer, Frankfurt, Germany (O-451)Simulation of the function of biomolecular machines


11:10 – 11:35 Johan Åqvist, Uppsala, Sweden (O-452)Computing the temperature dependence of chemical reactions inside and outside of living things

11:35 – 11:50 Katarzyna B. Koziara, St Lucia, Australia (O-453)Validation and development of force field parameters for drug and drug-like molecules

11:50 – 12:05 Till Rudack, Urbana, United States (O-454)Ubiquitin recruitment and transport by the proteasome unraveled by an orchestra of MD simulations

12:05 – 12:20 Andela Šarić, Cambridge, United Kingdom (O-455)Crucial role of non-specific interactions in amyloid nucleation

PARALLEL SESSIONS

Plenary Hall

14. SYSTEMS BIOLOGY AND MULTI-CELLULAR SYSTEMSChairs: Frank Jülicher, Germany & Jacques Prost, France

09:50 – 10:15 Kinneret Keren, Haifa, Israel (O- 519)Actomyosin force generation directs hydra regeneration

10:15 – 10:40 Pierre- François Lenne, Marseille, France (O-520)Mechanics of cell contacts during tissue morphogenesis


11:10 – 11:35 Primož Ziherl, Ljubljana, Slovenia (O-521)Quantitative morphology of epithelial folds

11:35 – 11:50 Jaume Casademunt, Barcelona, Spain (O-522)Mechanical instabilities in epithelial monolayers: elastic waves in a viscous medium?

11:50 – 12:05 Imre Derenyi, Budapest, Hungary (O-523)On cancer risk and the number of stem cell divisions

12:05 – 12:20 Keith R. Willison, London, United Kingdom (O-524)Absolute quantification of protein copy number in single cells using single molecule microarrays

Hall 1Plenary Hall


15. BIOLOGICALLY ACTIVE PEPTIDESChair: Thomas Gutsmann, Germany

09:50 – 10:15 Cait E. MacPhee, Edinburgh, United Kingdom (O-537)Peptide aggregation reduces the bioactivity of an HIV selective-inhibitor peptide

10:15 – 10:40 José L. Nieva, Bilbao, Spain (O-538)Membrane destabilization by the HIV-1 gp41 MPER-TMD region: mechanism and blocking by antibodies


11:10 – 11:35 Roland Brock, Nijmegen, The Netherlands (O-539)Structure and function of cell-penetrating peptides

11:35 – 11:50 Alejandra de Miguel, Berlin, Germany (O-540)Structure and dynamics of lantibiotics by molecular dynamics simulations: a fundamental approach towards antimicrobial activity

11:50 – 12:05 Sonia T. Henriques, Brisbane, Australia (O-541)Cyclotides, stable drug scaffolds that enter cells after binding to PE-phospholipids

12:05 – 12:20 Ilaria Serra, Monserrato, Italy (O-542)Synthetic dendrimeric peptides with β-sheet structure and membranolytic activity

12:20 – 14:45 Lunch, Posters & ExhibitsRegular posters: odd poster numbersLate posters: topics S10 - S24please see page 16 for poster plan

Industry Talks13:00 - 13:30 | Asylum Research, an Oxford Instruments Company 14:00 - 14:30 | Dynamic Biosensors GmbHplease see page 49 for additional information

Hall 2 PLENARY LECTURE Chair: Ilpo Vattulainen, Finland

14:45 – 15:30

Raymond E. Goldstein, Cambridge, United Kingdom (O-7)Synchronization of eukaryotic flagella

NEW AND NOTABLE Chair: Hans-Joachim Galla, Germany

15:30 – 15:55

Holger Stark, Göttingen, Germany (O-12)Breaking the 3Å resolution barrier in single particle cryo-EM


Plenary Hall

Plenary Hall

16. MEMBRANES AND VESICLES Chairs: Kai Simons, Germany & Manuel Prieto, Portugal

16:25 – 16:50

Reinhard Lipowsky, Potsdam, Germany (O-551)Membranes and vesicles with bilayer asymmetry

16:50 – 17:15 Patricia Bassereau, Paris, France (O-552)Shaping and scission of membranes with BAR-domain proteins

17:15 – 17:25 Break

17:25 – 17:50 John M. Seddon, London, United Kingdom (O-553)Lipid bicontinuous cubic phases: effects of chain-branching and hydrostatic pressure

17:50 – 18:05 Patricia A. T. Martins, Coimbra, Portugal (O-554)Kinetics and thermodynamics of CPZ interaction with lipid bilayers: effect of charge and cholesterol

PARALLEL SESSIONS

Plenary Hall

Hall 2

Tuesday, July 21


18:05 – 18:20 Birgit Plochberger, Vienna, Austria (O-555)Receptor-mediated HDL-lipid uptake is regulated by elastic properties of the plasma membrane

18:20 – 18:35 Sarah Lee, Birmingham, United Kingdom (O-556)Characterisation of membrane protein ZipA in SMALPs gives a complimentary SAXS and Cryo-EM 3D model

17. COST SYMPOSIA UNDERSTANDING MOVEMENT AND MECHANISM IN MOLECULAR MACHINES/CMST (COST ACTION CM1306) AND BIOPHYSICS OF GPCRS (GLISTEN - COST ACTION CM1207) Chairs: Fraser MacMillan, United Kingdom & Anthony Watts, United Kingdom

16:25 – 16:45 James Errey, Hertfordshire, United Kingdom (O-605)Crystal structure of a class C GPCR – metabotropic Glutamate receptor 5 (mGluR5)

16:45 – 17:05 Elspeth F. Garman, Oxford, United Kingdom (O-606)Unambiguous and quantitative identification of metals in proteins

17:05 – 17:25 Matteo Levantino, Palermo, Italy (O-607)Observing myoglobin proteinquake with an X-ray free-electron laser

17:25 – 17:35 Break

17:35 – 17:55 Patricia M. Dijkman, Oxford, United Kingdom (O-608)Dynamic GPCR dimerisation probed by ensemble and single-molecule FRET, DEER, and simulations

17:55 – 18:15 Hugo Gutiérrez de Terán, Uppsala, Sweden (O-609)Understanding ligand binding and receptor selectivity through molecular simulations

18:15 – 18:35 Dagmar Klostermeier, Münster, Germany (O-610)Using smFRET to understand structure, function and dynamics of molecular machines

Hall 1

18. PROTEIN FOLDING, ASSEMBLY AND STABILITYChairs: Thomas Kiefhaber, Germany & André Matagne, Belgium

16:25 – 16:50 Jochen Balbach, Halle(Saale), Germany (O-611)Probing protein energy landscapes by high-pressure NMR

16:50 – 17:15 Rudolf Glockshuber, Zurich, Switzerland (O-612)Mechanism of assembly and shear force dependent adhesion of type 1 pili from uropathogenic E. coli

17:15 – 17:25 Break

17:25 – 17:50 Simon Ebbinghaus, Bochum, Germany (O-614)Protein folding and stability: From the test tube to the cell

17:50 – 18:05 Didier Law-Hine, Orsay, France (O-615)Self-assembly kinetics of virus-like particles probed by time-resolved small-angle X-ray scattering

18:05 – 18:20 Toshifumi Mori, Okazaki, Japan (O-616)Theoretical study of the dynamic heterogeneity in the protein folding/unfolding transitions

18:20 – 18:35 Andrea Schulze, Würzburg, Germany (P-638)Local motions within the Hsp90 molecular chaperone machinery observed by fluorescence quenching

19:30 - 23:30 Congress Dinner(see page 51 for details)

Hall 2

Terrace Level

Tuesday, July 21


Wednesday, July 22

PLENARY LECTURE Chair: Manuel Prieto, Portugal

09:00 – 09:45 Christian Eggeling, Oxford, United Kingdom (O-8)Advanced optical microscopy for deeper insights into membrane bioactivity

19. CHANNELS AND TRANSPORTERSChairs: Reinhard Seifert, Germany & Manuela M. Pereira, Portugal

09:50 – 10:15 Anna Moroni, Milan, Italy (O-642)Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function

10:15 – 10:40 Thomas Voets, Leuven, Belgium (O-643)Function and modulation of TRP channels in the somatosensory system


11:10 – 11:35 Peter Hegemann, Berlin, Germany (O-644)Light-induced conformational changes in ion channels and transporters

11:35 – 11:50 Shreyas S. Kaptan, Göttingen, Germany (O-645)Is H95 a pH gate in AQP4?

11:50 – 12:05 Doris Höglinger, Heidelberg, Germany (O-646)Sphingosine influences acidic store calcium signaling via two-pore channel 1

12:05 – 12:20 Florian Hilbers, Aarhus, Denmark (O-647)A systematic study of alpha and beta subunit combinations of the Na,K-ATPase

PARALLEL SESSIONS

Plenary Hall

20. CELL BIOPHYSICS AND SIGNALLINGChairs: Jochen Guck, Germany & László Mátyus, Hungary

09:50 – 10:15 Sarah Köster, Göttingen, Germany (O-676)Intermediate filaments - mechanical building blocks and dynamic elements of the cell

10:15 – 10:40 Marcos Gonzalez-Gaitan, Geneva, Switzerland (O-677)The basis of the asymmetric targeting of endosomes during asymmetric division


11:10 – 11:35 Kevin J. Chalut, Cambridge, United Kingdom (O-678)Nuclear mechanics and shape in embryonic stem cells exiting pluripotency

11:35 – 11:50 Jorge De-Carvalho, Oeiras, Portugal (O-679)Space constraints in mitosis – study of cell internal biophysics outside the syncytial insect embryo

11:50 – 12:05 Oliver Otto, Dresden, Germany (O-680)Real-time deformability cytometry: mechanical phenotyping for label-free cell functional assays

12:05 – 12:20 Astrid Wahl, Marseille, France (O-681)T-lymphocyte spreading on soft substrates

Hall 2Plenary Hall


21. INTRINSICALLY DISORDERED PROTEINSChairs: Jörg Enderlein, Germany & Hagen Hofmann, Israel

09:50 – 10:15 Sonia Longhi, Marseille, France (O-711)Mechanisms of partner recognition by intrinsically disordered proteins

10:15 – 10:40 Pau Bernadó, Montpellier, France (O-712)Towards the characterization of the plasticity of biomolecular complexes involving IDPs


11:10 – 11:35 Felix Ritort, Barcelona, Spain (O-713)Mechanical folding and unfolding of protein barnase at the single-molecule level

11:35 – 11:50 Garegin A. Papoian, College Park, United States (O-714)The acetylation landscape of the H4 histone tail

11:50 – 12:05 François-Xavier Theillet, Berlin, Germany (O-715)Disorder and residual helicity control p53 signaling in cells

12:05 – 12:20 Sara M. Vaiana, Tempe, United States (O-716)Evidence for internal friction in IDPs of the Calcitonin peptide family

12:20 – 14:45 Lunch, Posters & ExhibitsRegular posters: even poster numbersLate posters: topics S10 - S24please see page 16 for poster plan

Industry Talk14:00 - 14:30 | IOP Publishingplease see page 49 for additional information

Hall 2 PLENARY LECTURE Chair: Stefan Diez, Germany

14:45 – 15:30

Marileen Dogterom, Delft, The Netherlands (O-9)Minimal systems for the study of microtubule-based cell polarity in fission yeast

NEW AND NOTABLE Chair: Anthony Watts, United Kingdom

15:30 – 15:55

Jean-Pierre Simorre, Grenoble, France (O-13)NMR of the bacterial cell surface and antibiotics resistance


Plenary Hall

Plenary Hall

22. PROTEIN-LIPID INTERACTIONSChairs: Anne-Claude Gavin, Germany & Pavel Jungwirth, Czech Republic

16:25 – 16:50

Reinhard Jahn, Göttingen, Germany (O-722)Membrane fusion mediated by SNARE proteins

16:50 – 17:15 Emad Tajkhorshid, Urbana, United States (O-723)Visualizing complex functional motions of membrane transporters at an atomic resolution

17:15 – 17:25 Break

17:25 – 17:50 Stephen H. White, Irvine, United States (O-724)Dropping out: The metastability of single-span transmembrane helices in the E. coli inner membrane

17:50 – 18:05 Karim Fahmy, Dresden, Germany (O-725)Water mobility at the active site of an ion transporter

PARALLEL SESSIONS

Plenary Hall

Hall 2

Wednesday, July 22


18:05 – 18:20 Volker Kiessling, Charlottesville, United States (O-726)Unraveling protein-protein and protein-lipid interactions of SNARE proteins using FLIC microscopy

18:20 – 18:35 Annette Meister, Halle (Saale), Germany (O-727)Supramolecular organization of the human N-BAR domain on sarcolemma model membranes

23. MOLECULAR RECOGNITIONChairs: Hans-Joachim Galla, Germany & Fredrik Höök, Sweden

16:25 – 16:50 Philipp Kukura, Oxford, United Kingdom (O-753)Interferometric scattering microscopy: high-speed nanometry and ultra-sensitive label-free imaging

16:50 – 17:15 Horst Vogel, Lausanne, Switzerland (O-754)Signal transmission by ligand-gated ion channels

17:15 – 17:25 Break

17:25 – 17:50 Claudia Steinem, Göttingen, Germany (O-755)A conformational switch: How ezrin links the cytoskeleton to the plasma membrane

17:50 – 18:05 Marta Bally, Göteborg, Sweden (O-756)Surface immobilized glycosaminoglycans to study the binding and release of herpes simplex viruses

18:05 – 18:20 Christian Meyners, Darmstadt, Germany (O-757)Isoform selective inhibition of histone deacetylase-like amidohydrolases

18:20 – 18:35 Nuno C. Santos, Lisbon, Portugal (O-758)Atomic force microscopy as a nanotool to evaluate cardiovascular patients’ risk

Hall 1

24. NeurosciencesChairs: Peter Hegemann, Germany & Kristian Franze, United Kingdom

16:25 – 16:50 Paul A. Janmey, Philadelphia, United States (O-772)Mechanical sensing by normal and transformed glial cells

16:50 – 17:05 Anne Desmazieres, Paris, France (O-773)Molecular mechanisms underlying nodal protein assembly prior to myelination in the CNS

17:05 – 17:15 Break

17:15 – 17:40 Tobias Moser, Göttingen, Germany (O-774)Employing optogenetics for auditory neuroscience and cochlear implants

17:40 – 18:05 Detlev Schild, Göttingen, Germany (O-775)Smelling cool: integration odors and temperature in the olfactory system of X. laevis

18:05 – 18:20 Albrecht Haase, Trento, Italy (O-776)Evidence for molecular vibration sensing in insect odour perception

18:20 – 18:35 Maxim Igaev, Osnabrück, Germany (O-777)The Tau-microtubule interaction unexpectedly resolved

18:35 - 19:15 Poster Awards, Closing Ceremony and Farewell Cocktail (see pages 19 and 51 for details)

Hall 2

Plenary Hall

Wednesday, July 22


Industry Talks

Applied Photophysics Ltd. The Future of CD Spectroscopy – The Power of Quantitative Circular DichroismDr. Anna Łęczkowska, Applied Photophysics Ltd., United KingdomSunday, July 19 | 13:00-13:30

Nanion Technologies GmbH Measure More Membrane: HTS Compatible Giga-Seal Patch Clamp, Cardiomyocytes and Artificial BilayersEkaterina Zaitseva & Gerhard Baaken, Nanion Technologies GmbH, GermanySunday, July 19 | 14:00-14:30

Malvern Instruments Ltd. Innovative Technologies for Advanced Characterization of Protein AggregatesJeffrey W. Hall, Malvern Instruments, United StatesMonday, July 20 | 13:00-13:30

Mad City Labs GmbH Modular Microscopy Systems for Single Molecule ImagingEric A. Drier, Mad City Labs Inc., United StatesMonday, July 20 | 14:00-14:30

Asylum Research Photothermal Excitation for Reliable and Quantitative AFMFlorian Johann, Asylum Research, an Oxford Instruments Company, GermanyTuesday, July 21 | 13:00-13:30

Dynamic Biosensors GmbH Biophysical Analysis of Molecular Interactions with Electro-Switchable BiosurfacesUlrich Rant, Dynamic Biosensors GmbH, GermanyTuesday, July 21 | 14:00-14:30

IOP Publishing Open access: IOP Publishing and the wider landscapeCarly Whittle, IOP Publishing, United KingdomWednesday, July 22 | 14:00-14:30

Hall 2

Hall 2

Hall 2

Hall 2

Hall 2

Hall 2

Hall 2


Social Programme

Welcome Reception - Saturday, July 18 | 18:00 – 19:00 The official welcome reception will be held in the exhibition area. You are invited to drinks and snacks.

Congress Dinner - Tuesday, July 21 | 19:30 - 23:30 The congress dinner will take place on the terrace level of the congress center. A dinner buffet and drinks will be offered. Enjoy the unique panoramic view of the historic city center in a relaxed atmosphere with colleagues.

Farewell Cocktail – Wednesday, July 22 | 18:35 - 19:00 We invite you to enjoy a farewell cocktail.

Optional tours: City Tour Dresden – Sunday, July 19 | 19:00 – 20:00Enjoy a guided walking tour through the inner city and learn about Dresden’s cultural, social and architectural history. Discover with other participants the highlights of “Venice at the Elbe River”. Tour will be given in English.

Meeting point: main entrance of the congress venue.Admission: € 15.00 per person

Tickets can be purchased at the registration desk (limited number of tickets available).

Bus trip to Meissen – Thursday, July 23 | 10:00 – 17:00 Experience how a piece of art is created while having a guided tour through the demonstration manufactory of the famous porcelain manufactory. Additionally, learn about the important sights of the medival city during a guided tour through the historic city centre. Tour will be given in English.

Meeting point: 09:45 at the main entrance of the congress venueAdmission: € 65.00 per Person

Tickets can be purchased at the registration desk (limited number of tickets available).

EBSA General Assembly Members of the EBSA Executive Committee, representatives of EBSA member societiesMonday, July 20 | 19:00 - 20:00

EBSA Executive Committee meetingsMembers of the EBSA Executive Committee, invited guestsSaturday, July 18 | 14:30 - 16:30Wednesday, July 22 | 13:00 - 14:30

European Biophysical Societies‘ Presidents meeting Presidents or Secretaries of member societies, invited guestssSunday, July 19 | 13:00 - 14:30

EBJ Editorial board meeting Members of the European Biophysics Journal (EBJ) Editorial Board, invited guestsTuesday, July 21 | 13:00 - 14:30

German Biophysical Society (DGfB) General Assembly Members of the German Biophysical Society (DGfB)Monday, July 20 | 13:00 - 13:30

Plenary Hall

Seminar room 5

Seminar room 5

Seminar room 5

Seminar room 5

Special Meetings


VenueMaritim Hotel & International Congress Center Dresden – ICCDOstra-Ufer 2 01067 Dresden, Germany

GPS coordinates: Latitude: 51.0587 | Longitude: 13.731398

Please see page 14 for venue map & floor plan.

RegistrationRegistration is possible throughout the whole duration of the congress at the registration desk, which is located in the foyer of the hall level.Opening hours: Sunday, July 18 14:30 - 19:00 Saturday, July 19 - Wednesday, July 22 08:00 - 19:00

BadgeAttendants receive a name badge which allows entrance to the congress. All participants are asked to wear their badge at all times.

Certificate of AttendanceIf a certificate of attendance is required, please refer to the registration desk.

Photography & CopyrightTaking pictures and recording of any kind in the lecture halls and poster exhibition without the prior written consent of the presenter of the work recorded are prohibited. The official congress photo- and videographers are exempt from this rule and will be recording and taking pictures during the congress. If you do not want to be recorded, please address your objection to the conference secretariat.

CateringCoffee breaks: Coffee and tea will be offered.Lunch breaks: A lunch buffet with warm and cold food will be provided in the exhibition area starting at 12:20. Vegetarian food options will be available. Special diet is available upon request. Please contact the registration desk.Water will be available at water dispensers throughout the congress.Additional food and beverages can be purchased at the restaurant of the adjoining Maritim Hotel.

Internet Access Free wireless internet access will be provided during the congress. Name of network (SSID): EBSA WiFiPassword (network key): ebsa2015

Industry ExhibitionThe industry exhibition can be found within the exhibition area at the hall level. Please see page 15 for the list of exhibitors. Please see page 49 for further details on industry talks during lunch breaks.Opening hours: Sunday, July 18 18:00 - 19:30 Saturday, July 19 - Tuesday, July 21 09:00 - 17:30 Wednesday, July 22 09:00 - 16:30

Working Area Chairs and tables for individual use are provided in the exhibition area.

Transportation

Taxis can be found at the main entrance of the ICCD.

Parking is possible at the underground garage of the ICCD. at € 2.00 per hour / € 18.00 per day.

Public transport: The tram station closest to the congress center is “Kongresszentrum”, where lines 6 and 11 leave. Tickets can be purchased at the ticket machines in the tram (price single journey: € 2.20).

The main train station can be reached with tram line 11 (direction “Zschertnitz”) in approx. 20 minutes.

Every 30 minutes, the train line S2 to the Airport leaves from station “Dresden Mitte” (direction “Dresden Flughafen”), which is within walking distance of the venue.

Wardrobe & Luggage Storage Wardrobe and luggage storage service will be offered for free in the foyer of the hall level, next to the registration desk.

Smoking AreaSmoking is allowed outside of the congress venue. Please refer to the designated places in front of the ICCD.

CurrencyThe currency unit is Euro (EUR). An ATM can be found at the terrace level of the ICCD, close to the main entrance. You may exchange money at the travel bank in the main station or ask at the reception of your hotel for currency exchange services.

General Information


Dresden is the capital city of the Free State of Saxony in Germany. It is situated in a valley on the River Elbe and harbours 500.000 inhabitants. The city is world famous for its impressive architecture, arts collections and unique landscape of the Elbe valley making it known as “Venice at the Elbe River”.

Sightseeing Highlights:

Zwinger Palace – complex of museums and galleries surrounding a courtyard composing terraces and fountains

Semperoper – opera house of the Saxon State Opera with a long history of premieres, including major works by Richard Wagner and Richard Strauss

Frauenkirche – Protestant church, destroyed during World War II, reconstructed and inaugurated 60 years later in 2005

Dresden Elbe Valley – former world heritage site, a unique landscape combining baroque architecture, an urban area setting and natural river banks and slopes

Dresden Flyer with further information is available at the registration desk.

Dresden

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Bus Terminal „Schlesischer Platz“

Bus Terminal „Bayrische Straße”

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Hotel ibis budget Dresden City

cityherberge Dresden

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SA G

ener

al As

sem

blyfro

m 19

:30Co

ngre

ss Di

nner

from

18:35

Poste

r Awa

rds,

Closin

g Ce

rem

ony a

nd Fa

rewe

ll Coc

ktail

PLEN

ARY

Mat

thias

Rief

PLEN

ARY

Ange

la M

. Gro

nenb

orn

PLEN

ARY

Raym

ond E

. Gold

stein

PLEN

ARY

Mar

ileen

Dog

tero

m

PLEN

ARY

Iva M

. Toli

ć

S01 PROTEIN STRUCTURE AND FUNCTION

S02 SYNTHETIC BIOLOGY AND NANOBIOPHYSICS

S03 LIVE IMAGING AND OPTICAL MICROSCOPY

S07 MEMBRANE STRUCTURE AND DOMAINS

S08 SINGLE MOLECULE BIOPHYSICS

S09 MATERIAL SCIENCE IN BIOPHYSICS

S13 BIOMOLECULAR SIMULATION AND

COMPUTATIONAL BIOPHYSICS

S14 SYSTEMS BIOLOGY AND MULTI-CELLULAR SYSTEMS

S15 BIOLOGICALLY ACTIVE PEPTIDES

S19 CHANNELS AND TRANSPORTERS

S20 CELL BIOPHYSICS AND SIGNALLING

S21 INTRINSICALLY DISORDERED PROTEINS

S04 PHOTOBIOPHYSICS AND BIOLOGICAL ELECTRON AND

PROTON TRANSFER

S05 MOLECULAR MOTORS

S06 SUPRAMOLECULAR ASSEMBLIES AND

AGGREGATION

S10 PROTEIN-NUCLEIC ACID INTERACTIONS

S11 NEW METHODS FOR COMPUTATIONAL BIOPHYSICS

S12 BIOSPECTROSCOPY, EPR AND NMR

S16 MEMBRANES AND VESICLES

S17 COST SYMPOSIA: MOLECULAR MACHINES &

GPCRS/GLISTEN

S18 PROTEIN FOLDING, ASSEMBLY AND STABILITY

S22 PROTEIN-LIPID INTERACTIONS

S23 MOLECULAR RECOGNITION

S24 NEUROSCIENCES

PLEN

ARY

Mar

tin Fu

ssene

gger

PLEN

ARY

J. An

toine

tte Ki

llian

PLEN

ARY

Chris

tian E

ggeli

ng

New&

Nota

ble: K

. Dud

ersta

dt

New&

Nota

ble: J

. D. B

runn

erNe

w&No

table

: H. S

tark

New&

Nota

ble: J

.-P. S

imor

re

Thursday, July 23, – 10.00 - 17.00 – Optional tour – Bus trip to Meissen

Indu

stry

Talks

Indu

stry

Talks

Indu

stry

Talks

Lunc

h Bre

ak

from

18:00

Welc

ome

Rece

ption

15:55

– 16

:25Co

�ee B

reak

10:40

– 11

:10Co

�ee B

reak

14:45

16:25

12:20

WEL

COM

E AD

DRES

S

PLEN

ARY

G. vo

n Heij

ne

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