CURRICULUM VITAE

Eric Gerd Pamer, M.D.

PERSONAL INFORMATION

Date of Birth: June 4, 1955 Office Address: Memorial Sloan-Kettering Cancer Center

Department of Medicine Infectious Diseases Service 1275 York Avenue # Box 9 New York, NY 10065 Office Phone: (646) 888-2679 Office Fax: (212) 422-0502 E-mail: pamere@mskcc.org EDUCATION 1973-1977 Case Western Reserve University, Cleveland, Ohio B.A., Biology 1978-1982 Case Western Reserve Medical School, Cleveland, Ohio M.D. POSTGRADUATE EDUCATION

1982-1983 Resident, Department of Surgery, UCSD, San Diego, California.

1983-1985 Resident, Department of Internal Medicine, UCSD, San Diego, California.

1985-1986 Chief Resident, Department of Internal Medicine, UCSD, San Diego, California.

1986-1989 Fellow, Division of Infectious Diseases, UCSD, San Diego, California.

1989-1990 Research Fellow, Scripps Clinic and Research Foundation, La Jolla, California.

FACULTY EMPLOYMENT

1990-1992 Acting Instructor, Department of Immunology and Department of Internal Medicine, Division of Infectious Diseases,

University of Washington, Seattle, Washington 1992-1996 Assistant Professor, Infectious Diseases Service, Department of

Medicine, Yale University, New Haven, Connecticut

1994-1996 Assistant Professor, Section of Immunobiology, Yale University, New Haven, Connecticut

1996-1999 Associate Professor, Infectious Diseases Service, Department of Medicine, Yale University, New Haven, Connecticut

1996-1999 Associate Professor, Section of Immunobiology, Yale

University, New Haven, Connecticut 1999-2000 Associate Professor with Tenure, Department of Medicine and

Section of Immunobiology, Infectious Diseases Service, Yale University, New Haven, Connecticut

2000-Present Member, Memorial Sloan-Kettering Cancer Center, Chief, Infectious Diseases Service, Department of Medicine, New York, New York 2001-Present Professor, Program in Immunology Weill Graduate School of Medical Sciences, New York, New York 2001-Present Professor, Department of Medicine

Joan and Sanford I. Weill Medical College of Cornell University, New York, New York

2006-Present Member, Department of Clinical Laboratories Memorial Sloan-Kettering Cancer Center 2010-Present Director, The Lucille Castori Center for Microbes, Inflammation

and Cancer, Memorial Sloan-Kettering Cancer Center 2011-Present Head, Division of General Medicine, Department of Medicine,

Memorial Sloan-Kettering Cancer Center HONORS

1976 Phi Beta Kappa 1981 Alpha Omega Alpha 1998 American Society for Clinical Investigation 2001 Enid A. Haupt Chair in Clinical Investigation 2010 IDSA Fellow 2011 Member, American Association of Physicians

AWARDS

1988 NIH Individual National Research Service Award 1989 NIH Clinical Investigator Award 1993 Arthritis Investigator Award 1994 Smith-Kline Beecham Young Investigator Award 1994 Pew Scholar in the Biomedical Sciences

1999 Donaghue Investigator Award

2002 Sandler Foundation Award for Asthma Research 2007 NIH Merit Award BOARD CERTIFICATION 1986 Internal Medicine 1994, 2004 Infectious Diseases NATIONAL COMMITTEES 1993-1996 Arthritis Foundation National Peer Review Study Section Molecular Immunology Subsection 1995-1996 Chairman, Molecular Immunology Study Section, Arthritis

Foundation 5/1998 National Institute of Allergy and Infectious Diseases (NIAID)

Focus Group, National Institutes of Health, Bethesda, Maryland 11/1998 National Institute of Allergy and Infectious Diseases Special Emphasis Panel

Application of Data on HLA and CD1 to Improvement of Vaccines

2/2001 Board of Scientific Advisors, Ad Hoc member National Institutes of Health 6/2002 Bacteriology and Mycology 2 Study Section Ad Hoc Member National Institutes of Health 2002-Present Scientific Advisory Board Trudeau Institute Saranac Lake, New York 2001-2006 Board of Scientific Advisors

Canadian Network for Vaccines and Immunotherapies (CANVAC)

2005-2007 Immune Epitope Database and Discovery Contracts Committee Special Study Section 2006-2009 American Association of Immunologists Clinical Immunology Committee Bethesda, MD 7/2009 National Institute of Health/Center for Scientific Review Distinguished Editorial Panels Bethesda, MD 2009-2010 Inimex Scientific Advisory Board, Vancouver, Canada 2/2010 Immunity and Host-defense study section, Ad Hoc Member,

NIH

3/2010 Review of RFA-AI-09-040 (U19) applications; NIH, Bethesda, MD

3/2010 and 5/2010 ANR "Integrated Mechanisms of Inflammation" Evaluation

Committee; Paris, France

12/2010 Ad Hoc Member, NIH/NIAID Board of Scientific Counselors 2010 American Association of Immunologists Nominating Committee 9/2010-2013 Member, St. Jude Children’s Research Hospital, Scientific

Advisory Board EDITORIAL BOARDS

1998-2004 Microbes and Infection 2000-2004 Journal of Immunology 2000-2006 Immunity 2002-2006 Journal of Experimental Medicine 2005-2008 Journal of Clinical Investigation 2005-2009 Annual Reviews of Immunology ACTIVE GRANTS

7/1/96-2/28/17 1R37AI39031 (Pamer) CC-Chemokines in Listeria Infection

12/1/98-4/30/14 1RO1 AI42135 (Pamer) Innate Immune responses to Intestinal Microbiota 7/1/09-6/30/14 1R01 AI080619-02 (Pamer and Glickman) CD4 T Cell Responses to M. tuberculosis Infection 7/1/12-6/30/16 R01 AI095706 (Pamer) Innate Immune Defense Against C. difficile Infection 4/1/13-3/31/18 2PO1 CA23766-34 (Pamer and O’Reilly)

The Immunobiology of Marrow Allografts for Leukemia (Project 2: Monocytes and the Intestinal Microbiota Following ALLO-HSCT)

COMPLETED GRANTS 5/8/02-5/7/07 PO1 CA23766-25 Repertoire and Avidity of Anti-Viral T-cells

5/8/02-5/7/07 PO1 CA23766-25 Core C: MHC Tetramer Core 6/1/09-5/31/10 UL1 RR024996

Microbial flora associated with the development of Clostridium difficile colitis

7/1/04-6/30/10 1T32 AI055409 Research Training in Infectious Diseases 2/1/06-1/31/11 1RO1 AI067359-01 (Pamer)

Characterization of Aspergillus fumigatus specific CD4 T cell responses

6/1/06-5/31/11 PO1 AI071195-05 (Chakraborty) Immune Response Consortium: Integrated In Silico, In Vitro, and In Vivo Studies

9/30/09-9/29/11 1RC2AR058986-02 (Abramson)

Role of gut microbiota in Rheumatoid Arthritis 9/1/07-2/28/12 P01 CA023766-30 (O’Reilly) The Immunobiology of Marrow Allografts for Leukemia ORIGINAL ARTICLES:

1. Pamer EG, So M, and Davis CE. Identification of a developmentally regulated cysteine protease of Trypanosoma brucei. Molecular and Biochemical Parasitology. 1989; 33:27-32.

2. Pamer EG, Davis CE, Eakin A and So M. Cloning and sequencing of the cysteine protease cDNA from Trypanosoma brucei rhodesiense. Nucleic Acids Research. 1990; 18(20):6141.

3. Pamer EG, Davis CE and So M. Expression and deletion analysis of the Trypanosoma brucei rhodesiense cysteine protease in Escherichia coli. Infection and Immunity. 1991; 59:1074-1078.

4. Pamer EG, Harty JT, and Bevan MJ. Precise prediction of a dominant class I MHC restricted epitope of Listeria monocytogenes. Nature. 1991; 353:852-855.

5. Pamer EG, Wang CR, Flaherty L, Lindahl KF, and Bevan MJ. H-2M3 presents a Listeria monocytogenes peptide to cytotoxic T lymphocytes. Cell. 1992; 70:215-223.

6. Wipke B, Jameson S, Bevan MJ, and Pamer EG. Variable binding affinities of listeriolysin O peptides for the H-2Kd class I molecule. European Journal of Immunology. 1993; 23:2005-2010.

7. Pamer EG. Direct sequence identification and kinetic analysis of an MHC class I restricted Listeria monocytogenes CTL epitope. Journal of Immunology. 1994; 152:686-694.

8. Villanueva MS, Fischer P, Feen K, and Pamer EG. Efficiency of MHC class I antigen processing: a quantitative analysis. Immunity. 1994; 1:479-489.

9. Villanueva MS, Beckers CJ, and Pamer EG. Infection with Listeria monocytogenes impairs sialic acid addition to host cell glycoproteins. The Journal of Experimental Medicine. 1994; 180:2137-2145.

10. Smith GP, Dabhi VM, Pamer EG, and Lindahl KF. Peptide presentation by the MHC class Ib molecule, H2-M3. International Immunology. 1994; 6:1917-1926.

11. Harty JT, and Pamer EG. CD8 T lymphocytes specific for the secreted p60 antigen protect against Listeria monocytogenes infection. Journal of Immunology. 1995; 154:4642-4650.

12. Villanueva MS, Sijts AJ, and Pamer EG. Listeriolysin is efficiently processed into an MHC class I associated epitope in Listeria monocytogenes infected cells. Journal of Immunology. 1995; 155:5227-5234.

13. Sijts AJ, Neisig A, Neefjes JJ, and Pamer EG. Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies. Journal of Immunology. 1996; 156:685-692.

14. Sijts AJ, Villanueva MS, and Pamer EG. CTL epitope generation is tightly linked to cellular proteolysis of a Listeria monocytogenes antigen. Journal of Immunology. 1996; 156:1497-1503.

15. An LL, Pamer EG, and Whitton JL. A recombinant minigene vaccine containing a nonameric CTL epitope confers limited protection against Listeria monocytogenes infection. Infection and Immunity. 1996; 64:1685-1693.

16. Gulden PH, Fischer P, Sherman NE, Wang W, Engelhard VE, Shabanowitz J, Hunt DF, and Pamer EG. A Listeria monocytogenes pentapeptide is presented to cytolytic T lymphocytes by the H2-M3 MHC class Ib molecule. Immunity. 1996; 5:73-79.

17. Vijh S, and Pamer EG. Immunodominant and subdominant CTL responses to Listeria monocytogenes infection. Journal of Immunology. 1997; 158:3366-3371.

18. Sijts AJ, and Pamer EG. Enhanced intracellular dissociation of MHC class I associated peptides: A mechanism for optimizing the spectrum of cell surface presented CTL epitopes. The Journal of Experimental Medicine. 1997; 185:1403-1412.

19. Sijts AJ, Pilip I, and Pamer EG. The Listeria monocytogenes secreted p60 protein is an N-end rule substrate in the cytosol of infected cells: Implications for MHC class I antigen processing of bacterial proteins. Journal of Biological Chemistry. 1997; 272:19261-19268.

20. Busch DH, Bouwer HG, Hinrichs D, and Pamer EG. A nonamer peptide derived from the Listeria monocytogenes metalloprotease is presented to cytotoxic T lymphocytes. Infection and Immunity. 1997; 65:5326-5329.

21. Vijh S, Pilip IM, and Pamer EG. Effect of antigen-processing efficiency on in vivo T cell response magnitudes. Journal of Immunology. 1998; 160:3971-3977.

22. Busch DH, Pilip IM, and Pamer EG. MHC class I/peptide stability: Implications for immunodominance, in vitro proliferation, and diversity of responding CTL. Journal of Immunology. 1998; 160:4441-4448.

23. Busch DH, Pilip IM, Vijh S, and Pamer EG. Coordinate regulation of complex T cell populations responding to bacterial infection. Immunity. 1998; 8:353-362.

24. Busch DH, Pilip IM, and Pamer EG. Evolution of a complex TCR repertoire during primary and recall bacterial infection. The Journal of Experimental Medicine. 1998; 188:61-70.

25. Vijh S, Pilip IM, and Pamer EG. Noncompetitive expansion of CTL specific for different antigens during bacterial infection. Infection and Immunity. 1999; 67:1303-1309.

26. Busch DH, and Pamer EG. T cell affinity maturation by selective expansion during infection. The Journal of Experimental Medicine. 1999; 189:701-709.

27. White DW, MacNeil A, Busch DH, Pilip IM, Pamer EG, and Harty JT. Perforin-deficient CD8+ T cells: priming and antigen-specific immunity against Listeria monocytogenes. Journal of Immunology. 1999; 162:980-988.

28. Kerksiek KM, Busch DH, Pilip IM, Allen SE, and Pamer EG. H2-M3 restricted T cells in bacterial infection: rapid primary but diminished memory responses. The Journal of Experimental Medicine. 1999; 190:195-205.

29. Hanke T, Takizawa H, McMahon CW, Busch DH, Pamer EG, Altman JD, Liu Y, Cado D, Lemonnier F, Bjorkman PJ, and Raulet DH. Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity. 1999; 11:67-77.

30. Wong FS, Karttunen J, Dumont C, Wen L, Visintin I, Pilip IM, Shastri N, Pamer EG, and Janeway CA. Identification of a MHC class I restricted autoantigen in type 1diabetes by screening an organ-specific cDNA library. Nature Medicine. 1999; 5:1026-1031.

31. Chiu NM, Wang B, Kerksiek KM, Kurlander R, Pamer EG, and Wang CR. The selection of M3-restricted T cells is dependent on M3 expression and presentation of N-formylated peptides in the thymus. The Journal of Experimental Medicine. 1999; 190:1869-1878.

32. Busch DH, Pamer EG. T lymphocyte dynamics during Listeria monocytogenes infection. Immunol Lett. 1999 Jan;65(1-2):93-8.

33. Nugent CT, Morgan DJ, Biggs JK, Ko A, Pilip I, Pamer EG, and Sherman LS. Characterization of CD8+ T lymphocytes which persist after peripheral tolerance to a self antigen expressed in the pancreas. Journal of Immunology. 2000; 164:191-200.

34. Busch DH, Kerksiek KM, and Pamer EG. Differing roles of inflammation and antigen in T cell proliferation and memory generation. Journal of Immunology. 2000; 164:4063-4070.

35. Marshall NA, Howe JG, Krause D, Berliner N, Crouch J, Pilip I, Cooper D, Seropian S and Pamer EG. Rapid reconstitution of Epstein Barr Virus specific T lymphocytes following allogeneic peripheral blood stem cell transplantation. Blood. 2000; 96:2814-2821.

36. Mercado R, Vijh S, Allen SE, Pilip IM, and Pamer EG. Early programming of T cell populations responding to bacterial infection. Journal of Immunology. 2000; 165:6833-6839.

37. Kerksiek K, Busch D, and Pamer EG. Variable Immunodominance hierarchies for H2-M3 restricted N-formyl peptides following bacterial infection. Journal of Immunology. 2001; 166:1132-1140.

38. Huleatt JW, Pilip I, Kerksiek K and Pamer EG. Intestinal and splenic T cell responses to enteric Listeria monocytogenes infection: Distinct repertoires of responding CD8 T lymphocytes. Journal of Immunology. 2001; 166:4065-4073.

39. Yajima T, Nishimura H, Ishimitsu R, Yamamura K, Watase T, Busch DH, Pamer EG, Kuwano H, and Yoshikai, Y. Memory phenotype CD8+ T cells in IL-15 transgenic mice are involved in early protection against primary infection with Listeria monocytogenes. European Journal of Immunology. 2001; 31:757-766.

40. Wong P, and Pamer EG. Cutting edge: Antigen-independent CD8 T cell proliferation. Journal of Immunology. 2001; 166:5864-5868.

41. Kreuwel HT, Biggs JA, Pilip IM, Pamer EG, Lo D, and Sherman LA. Defective CD8 T cell peripheral tolerance in nonobese diabetic mice (NOD). Journal of Immunology. 2001; 167:1112-1117.

42. Lauvau G, Vijh S, Kong P, Horng T, Kerksiek K, Serbina N, Tuma RA, and Pamer EG. Priming of memory but not effector CD8 T cells by a killed bacterial vaccine. Science. 2001; 294(5547):1735-1739.

43. Lauvau G, Pamer EG. CD8 T cell detection of bacterial infection: sniffing for formyl peptides derived from Mycobacterium tuberculosis. J Exp Med. 2001 May 21;193(10):F35-9.

44. Yajima T, Nishimura H, Ishimitsu R, Watase T, Busch DH, Pamer EG, Kuwano H, and Yoshikai Y. Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure. J Immunol. 2002 Feb 1; 168(3):1198-203.

45. Koehne G, Smith KM, Ferguson TL, Williams RY, Heller G, Pamer EG, Dupong B, O’Reilly RJ. Quantitation, selection, and functional characterization of Epstein-Barr virus-specific and alloreactive T cells detected by intracellular interferon-gamma production and growth of cytotoxic precursors. Blood. 2002 Mar 1;99(5):1730-40.

46. Haglund K, Leiner I, Kerksiek K, Buonocore L, Pamer E, and Rose JK. High-level primary CD8 (+) T-cell response to human immunodeficiency virus type 1 gag and env generated by vaccination with recombinant vesicular stomatitis viruses. J Virol. 2002 Mar;76(6):2730-8.

47. Jung S, Unutmatz D, Wong P, De los Santos K, Sparwasser T, Wu S, Vuthoori S, Ko K, Pamer EG, Littman DR, and Lang R. In vivo depletion of CD11c-positive dendritic cells abrogates priming of CD8-postitive T cells by exogenous cell-associated antigens. Immunity. 2002; 17:211-220.

48. Goodman D, Pamer EG, Jakubowski A, Morris C, and Sepkowitz K. Breakthrough trichosporonosis in a bone marrow transplant recipient receiving caspofungin acetate. Clinical Infectious Disease. 2002; 35: E35-36.

49. Koelle DM, Liu Z, McClurkan CM, Topp M, Riddell SR, Pamer EG, Johnson AS, Wald A, and Corey L. Expression of cutaneous lymphocyte-associated antigen by CD8+ T cells specific for a skin-tropic virus. Journal of Clinical Investigation. 2002; 110:537-548.

50. Haglund K, Leiner I, Kerksiek K, Buonocore L, Pamer EG, and Rose JK. Robust recall and long-term memory T-cell responses induced by prime-boost regimens with heterologous live viral vectors expressing human immunodeficiency virus type 1 Gag and Env proteins. Journal of Virology. 2002; 76:7506-7517.

51. Tuma RA, Giannino R, Guirnalda P, Leiner I, and Pamer EG. Rescue of CD8 T cell-mediated anti-microbial immunity with a non-specific inflammatory stimulus. Journal of Clinical Investigation. 2002; 110:1493-1501.

52. Kerksiek KM, Ploss A, Leiner I, Busch DH, and Pamer EG. H2-M3 restricted memory T cells: persistence and activation without expansion. Journal of Immunology. 2003; 170:1862-1869.

53. Wong P, and Pamer EG. Feedback regulation of pathogen specific T cell priming. Immunity. 2003; 18(4): 499-511.

54. Meij P, Van Esser J, Niesters H, van Barle D, Miedema F, Blake N, Rickinson A, Leiner I, Pamer E, Lowenberg B, Cornelissen J, and Gratama J. Impaired recovery of Epstein-Barr virus (EBV)-specific CD8+ T lymphocytes after partially T-depleted allogenic stem cell transplantation identifies patients at very high risk for progressive EBV reactivation and lymphoproliferative disease. Blood. 2003; 101(11): 4290-4297.

55. Van Epps H, Feldmesser M, and Pamer EG. Voriconazole inhibits fungal growth without impairing antigen presentation or T-cell activation. Antimicrobial Agents and Chemotherapy. 2003; 47(6): 1818-1823.

56. Papanicolaou GA, Latouche JB, Tan C, Dupont J, Stiles J, Pamer EG, Sadelain M. Rapid expansion of cytomegalovirus-specific cytotoxic T lymphocytes by artificial antigen-presenting cells expressing a single HLA allele. Blood. 2003 Oct 1;102(7):2498-505.

57. Serbina N, Salazar-Mather T, Biron C, Kuziel W, and Pamer EG. TNF/iNOS-producing

dendritic cells mediate innate immune defense against bacterial infection. Immunity. 2003; 19(1):59-70.

58. Ploss A, Lauvau G, Contos B, Kerksiek K, Guirnalda P, Leiner I, Lenz L, Bevan M, and Pamer EG. Promiscuity of MHC class Ib restricted T cell responses. Journal of Immunology. 2003; 171(11): 5948-5955.

59. Serbina N, Kuziel W, Flavell R, Akira S, Rollins B, and Pamer EG. Sequential MyD88-independent and dependent activation of innate immune responses to intracellular bacterial infection. Immunity. 2003; 19(6):891-901.

60. Kang I, Quan T, Nolasco H, Park S, Hong M, Pamer EG, Crouch J, Howe J, and Craft J. Defective control of latent EBV infection in systemic lupus erythematosus. Journal of Immunology. 2003; 172(2): 1287-1294.

61. Zhong MX, Kuziel WA, Pamer EG, and Serbina NV. Chemokine receptor 5 (CCR5) is dispensable for innate and adaptive immune responses to Listeria monocytogenes infection. Infection and Immunity. 2004; 72:1057-064.

62. Wong P, and Pamer EG. Disparate in vitro requirements for IL-2 during antigen-independent CD8 T cell expansion. Journal of Immunology. 2004; 172(4): 2171-2176.

63. Wong P, Lara-Tejero M, Ploss A, Leiner I, and Pamer EG. Rapid development of T cell memory. Journal of Immunology. 2004; 172(12):7239–7245.

64. Yuan R, Wong P, McDevitt M, Doubrovina E, Leiner I, Bornmann W, O'Reilly R, Pamer EG, and Scheinberg D. Targeted deletion of T cell clones using alpha emitting suicide MHC tetramers. Blood. 2004; 104(8):2397-2402.

65. Jaffe D, Jakubowski A, Sepkowitz K, Sebti R, Kiehn TE, Pamer E, and Papanicolaou GA. Prevention of Peri-Transplant Viridans Streptococcal Bacteremia with Early Vancomycin Administration: A Single Center Observational Cohort Study. Clinical Infectious Diseases. 2004; 39(11):1625-1632.

66. Doubrovina ES, Doubrovin MM, Lee S, Shieh J, Heller G, Pamer EG, and O’Reilly RJ. In vitro stimulation with WT1 Peptide Loaded EBV+ B cells elicits high frequencies of WT1 peptide specific T-cells with in vitro and in vivo tumoricidal activity. Clinical Cancer Research. 2004; 10(21):7207-7219.

67. Muraille E, Giannino R, Guirnalda P, Leiner I, Jung S, Pamer EG, and Lauvau G. Distinct in vivo dendritic cell activation by live versus killed Listeria monocytogenes. European Journal of Immunology. 2005; 35(5):1463-1471.

68. Almyroudis NG, Fuller A, Jakubowski A, Sepkowitz K, Jaffe D, Small TN, Kiehn TE, Pamer EG, and Papanicolaou GA. Pre- and post-engraftment bloodstream infection rates and associated mortality in allogeneic hematopoietic stem cell transplant recipients. Transplant Infectious Disease. 2005 7(1):11-17.

69. Lyman MA, Nugent CT, Marquardt KL, Biggs JA, Pamer EG, and Sherman LA. The fate of low affinity tumor-specific CD8+ T cells in tumor-bearing mice. Journal of Immunology. 2005; 174(5):2563-2572.

70. Ploss A, Leiner I, and Pamer EG. Distinct regulation of H2-M3-restricted memory T cell responses in lymph node and spleen. Journal of Immunology. 2005; 175:5998-6005.

71. Rivera A, Van Epps H, Rizzuto G, and Pamer EG. Distinct CD4+- T cell responses to live and heat-inactivated Aspergillus fumigatus conidia. Infection and Immunity. 2005; 73:7170-7179.

72. Hohl T, Van Epps H, Rivera A, Morgan L, Chen P, Feldmesser M, and Pamer EG. Aspergillus fumigatus Triggers Inflammatory Responses by Stage-Specific beta-Glucan Display. PLoS Pathogens. 2005; 1(3):232-240.

73. Ploss A, Tran A, Menet E, Leiner I, and Pamer EG. Cross-recognition of N-formylmethionine peptides is a general characteristic of H2-M3 restricted CD8+ T cells. Infection and Immunity. 2005; 73:4423-4426.

74. Kappel BJ, Pinilla-Ibarz J, Kochman AA, Eng JM, Hubbard VM, Leiner I, Pamer EG, Heller G, van den Brink MR, and Scheinberg DA. Remodeling specific immunity by use of MHC tetramers: demonstration in a graft-versus-host disease model. Blood. 2006; 107(5): 2045-2051.

75. Kesh S, Mensah NY, Peterlongo P, Jaffe D, Hsu K, van den Brink MR, O’Reilly R, Pamer EG, Satagopan J, and Papanicolaou GA. TLR1 and TLR6 polymorphisms are associated with susceptibility to invasive aspergillosis after allogeneic stem cell transplantation. Annals of the New York Academy of Science. 2006; 1062:95-103.

76. Serbina NV, and Pamer EG. Monocyte emigration from bone marrow during bacterial infection requires CCR2-mediated signals. Nature Immunology. 2006; 7(3): 311-317.

77. Rivera A, Ro G, Van Epps HL, Simpson T, Leiner I, Sant'Angelo D. B., and Pamer EG. Innate immune activation and CD4+ T cell priming during respiratory fungal infection. Immunity. 2006; 25(4):665-75.

78. Zakrzewski JL, Kochman AA, Lu SX, Terwey TH, Kim TD, Hubbard VM, Muriglan SJ, Suh D, Smith OM, Grubin J, Patel N, Chow A, Cabrera-Perez J, Radhakrishnan R, Diab A, Perales MA, Rizzuto G, Menet E, Pamer EG, Heller G, Zuniga-Pflucker JC, Alpdogan O, and van den Brink MR. Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation. Nature Medicine. 2006; 12(9):1039-47.

79. Tuma R, Almyroudis N, Sohn S, Panageas K, Rice R, Galinkin D, Blain M, Montefusco M, Pamer E, Nimer S, and Kewalramani T. The serum IL-12: IL-6 ratio reliably distinguishes infectious from non-infectious causes of fever during autologous stem cell transplantation. Cytotherapy. 2006; 8(4):327-334.

80. Symeonidis N, Jakubowski A, Pierre-Louis S, Jaffe D, Pamer EG, Sepkowitz K, O’Reilly RJ, Papanicolaou GA. Invasive adenoviral infections in T-cell-depleted allogeneic hematopoietic stem cell transplantation: high mortality in the era of cidofovir. Transpl Infect Dis. 2007; 9(2): 108-113.

81. Almyroudis NG, Jakubowski A, Jaffe D, Sepkowitz K, Pamer E, O’Reilly RJ, Papanicolaou GA. Predictors for persistent cytomegalovirus reactivation after T-cell-depleted allogeneic hematopoietic stem cell transplantation. Transpl Infect Dis. 2007; 9(4):286-294.

82. Brandl K, Plitas G, Schnobl B, DeMatteo RP, Pamer, EG. My D88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection. Journal of Experimental Medicine. 2007; 204(8):1891-1900.

83. Mihu CN, King E, Yossepovitch O, Taur Y, Jakubowski A, Pamer E, Papanicolaou, GA. Risk factors and attributable mortality of late aspergillosis after T-cell depleted hematopoietic stem cell transplantation. Transpl Infect Dis. 2007; 10(3):162-167.

84. Biswas PS, Pedicord V, Ploss A, Menet E, Leiner I, Pamer EG. Pathogen-specific CD8 T cell responses are directly inhibited by IL-10. Journal of Immunology. 2007; 179(7): 4520-4528.

85. Jia T, Serbina N, Brandl K, Zhong MX, Leiner IM, Charo IF, Pamer EG. Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection. Journal of Immunology. 2008; 180(10): 6846-6853.

86. Hohl TM, Feldmesser M, Perlin DS, Pamer EG. Caspofungin Modulates Inflammatory Responses to Aspergillus fumigatus through State-Specific Effects on Fungal beta-Glucan Exposure. Journal of Infectious Diseases. 2008; 198(2):176-185.

87. Brandl K, Plitas G, Mihu CN, Ubeda C, Jia T, Fleisher M, Schnabl B, DeMatteo RP, Pamer EG. Vancomycin-resistant enterococci exploit innate immune deficits induced by antibiotic treatment. Nature. 2008; 455(7214):804-807.

88. Gallegos AM, Pamer EG, Glickman MS. Delayed Protection by ESAT-6-Specific Effector CD4 (+) T Cells after Airborne Mycobacterium tuberculosis Infection. Journal of Experimental Medicine. 2008; 205(10):2359-2368.

89. Kamboj M, Gerbin M, Huang CK, Brennan C, Stiles J, Balashov S, Park S, Kiehn TE, Perlin DS, Pamer EG, Sepkowitz KA. Clinical characterization of human metapneumovirus infection among patients with cancer. Journal of Infection. 2008;57(6):464-71.

90. Mihu CN, Schaub J, Kesh S, Jakubowski A, Sepkowitz K, Pamer EG, Papanicolaou GA. Risk factors for late Staphylococcus aureus bacteremia after allogeneic stem cell transplantation: A single institution, nested case-control study. Biology of Blood Marrow Transplant. 2008;14(12):1429-33.

91. Mircescu M, Lipuma L, van Rooijen N, Pamer EG, Hohl TM. Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infection. Journal of Infectious Diseases. 2009 Aug 15;200(4):647-56.

92. Rivera A, Collins N, Stephan MT, Lipuma L, Leiner I, Pamer EG. Aberrant tissue localization of Fungus-Specific CD4+ T cells in IL-10-deficient mice. Journal of Immunology. 2009 Jul 1;183(1):631-41.

93. Jia T, Leiner I, Dorothee G, Brandl K, Pamer EG. MyD88 and type I interferon receptor-mediated chemokine induction and monocyte recruitment during Listeria monocytogenes infection. Journal of Immunology. 2009 Jul 15;183(2):1271-8.

94. Serbina NV, Hohl TM, Cherny M, Pamer EG. Selective expansion of the monocytic lineage directed by bacterial infection. Journal of Immunology. 2009 Aug 1;183(3):1900-10.

95. Serbina NV, Cherny M, Shi C, Bleau SA, Collins NH, Young JW, Pamer EG. Distinct Responses of Human Monocyte Subsets to Aspergillus fumigatus Conidia. Journal of Immunology. 2009 Aug 15;183(4):2678-87.

96. Mensah NY, Peterlongo P, Steinherz P, Pamer EG, Satagopan J, Papanicolaou GA. Toll-like receptor 4 polymorphisms and risk of gram-negative bacteremia after allogeneic stem cell transplantation. A prospective pilot study. Biol Blood Marrow Transplant. 2009 Sep;15(9):1130-3.

97. Hohl TM, Rivera A, Lipuma L, Gallegos A, Shi C, Mack M, Pamer EG. Inflammatory Monocytes Facilitate Adaptive CD4 T Cell Responses during Respiratory Fungal Infection. Cell Host Microbe. 2009 Nov 19;6(5):470-81.

98. Kinnebrew MA, Ubeda C, Zenewicz LA, Smith N, Flavell RA, Pamer EG. Bacterial flagellin stimulates TLR5-dependent defense against vancomycin-resistant Enterococcus infection. J Infect Dis. 2010 Feb 15;201(4):534-43.

99. Redelman-Sidi G, Sepkowitz KA, Huang CK, Park S, Stiles J, Eagan J, Perlin DS, Pamer EG, Kamboj MJ. 2009 H1N1 influenza infection in cancer patients and hematopoietic stem cell transplant recipients. J Infect. 2010 Apr;60(4):257-63.

100. Shi C, Velazquez P, Hohl TM, Leiner I, Dustin ML, Pamer EG. Monocyte trafficking to hepatic sites of bacterial infection is chemokine-independent and directed by focal ICAM-1 expression. Journal of Immunology. 2010 Jun 1;184(11):6266-74.

101. Kamboj M, Chung D, Seo SK, Pamer EG, Sepkowitz KA, Jakubowski AA, Papanicolaou G. The changing epidemiology of vancomycin-resistant Enterococcus (VRE) bacteremia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Biol Blood Marrow Transplant. 2010 Nov;16(11):1576-81.

102. Ubeda C, Taur Y, Jenq RR, Equinda MJ, Son T, Samstein M, Viale A, Socci ND, van den Brink MR, Kamboj M, Pamer EG. Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans. J Clin Invest. 2010 Dec 1;120(12):4332-41.

103. Rivera A, Hohl TM, Collins N, Leiner I, Gallegos A, Saijo S, Coward JW, Iwakura Y, Pamer EG. Dectin-1 diversifies Aspergillus fumigatus-specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation. J Exp Med. 2011 Feb 14;208(2):369-81.

104. Jarchum I, Liu M, Lipuma L, Pamer EG. Toll-Like Receptor 5 Stimulation Protects Mice from Acute Clostridium difficile Colitis. Infect Immun. 2011; 79(4):1498-503.

105. Waite JC, Leiner I, Lauer P, Rae CS, Barbet G, Zheng H, Portnoy DA, Pamer EG, Dustin ML. Dynamic imaging of the effector immune response to listeria infection in vivo. PLoS Pathog. 2011; 7(3):e1001326.

106. Shi C, Jia T, Mendez-Ferrer S, Hohl TM, Serbina NV, Lipuma L, Leiner I, Li MO, Frenette PS, Pamer EG. Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands. Immunity. 2011; 34(4):590-601.

107. Tagliani E, Shi C, Nancy P, Tay CS, Pamer EG, Erlebacher A. Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1. J Exp Med. 2011; 208(9):1901-16.

108. Gallegos AM, van Heijst JW, Samstein M, Su X, Pamer EG, Glickman MS. A Gamma Interferon Independent Mechanism of CD4 T Cell Mediated Control of M. tuberculosis Infection in vivo. PLoS Pathog. 2011 May;7(5):e1002052.

109. Shi C, Hohl TM, Leiner I, Equinda MJ, Fan X, Pamer EG. Ly6G+ neutrophils are dispensable for defense against systemic Listeria monocytogenes infection. Journal of Immunology. 2011; 187(10):5293-8.

110. Buffie CG, Jarchum I, Equinda M, Lipuma L, Gobourne A, Viale A, Ubeda-Morant C, Xavier J, Pamer EG. Profound alterations of intestinal microbiota following a single dose of Clindamycin results in sustained susceptibility to C. difficile-induced colitis. Infect Immun. 2012; 80(1):62-73.

111. Lesokhin A, Hohl TM, Kitano S, Cortez C, Hirschhorn-Cymerman D, Avogadri F, Rizzuto GA, Lazarus JJ, Pamer EG, Houghton AN, Merghoub T, Wolchok JD. Monocytic CCR2+ Myeloid Derived Suppressor Cells Promote Immune Escape By Limiting Activated CD8 T Cell Infiltration Into The Tumor Microenvironment. Cancer Res. 2012 Feb 15;72(4):876-86.

112. Kinnebrew, MA, Buffie, CG, Diehl, GE, Zenewicz, LA, Leiner, I, Hohl, TM, Flavell, RA, Littman, DR, Pamer EG. IL-23 production by intestinal CD103+CD11b+ dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense. Immunity. 2012 Feb 24;36(2):276-87.

113. Scher JU, Ubeda C, Equinda M, Khanin R, Buischi Y, Viale A, Lipuma L, Attur M, Pillinger MH, Weissmann G, Littman DR, Pamer EG, Bretz WA, Abramson SB. Periodontal

disease and the oral microbiota in new-onset rheumatoid arthritis. Arthritis Rheum. 2012 May 10. Doi: 10.1002/art.34539.

114. Jenq RR, Ubeda C, Taur Y, Menezes CC, Khanin R, Dudakov JA, Liu C, West ML, Singer NV, Equinda MJ, Gobourne A, Lipuma L, Young LF, Smith OM, Ghosh A, Hanash AM, Goldberg JD, Aoyama K, Blazar BR, Pamer EG, R M van den Brink M. Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation. J Exp Med. 2012 May 7;209(5):903-11.

115. Jarchum I, Liu M, Shi C, Equinda M, Pamer EG. Critical role for MyD88-mediated neutrophil recruitment during C. difficile colitis. Infect Immun. 2012 Jun 11.

116. Ubeda C, Lipuma L, Gobourne A, Viale A, Leiner I, Equinda M, Khanin R, Pamer EG. Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice. J Exp Med. 2012 Jul 30;209(8): 1445-56.

117. Taur Y, Xavier JB, Lipuma L, Ubeda C, Goldberg J, Gobourne A, Lee YJ, Dubin KA, Socci ND, Viale A, Perales MA, Jenq RR, van den Brink MR, Pamer EG. Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation. Clin Infect Dis. 2012 Oct;55(7):905-14.

118. Ubeda C, Bucci V, Caballero S, Djukovic A, Toussaint NC, Equinda M, Lipuma L, Ling L, Gobourne A, No D, Taur Y, Jenq RR, van den Brink MR, Xavier JB, Pamer EG. Intestinal microbiota containing Barnesiella species cures vancomycin-resistant Enterococcus faecium colonization. Infect Immun. 2013 Jan 14.

119. Ryder M, Gild M, Hohl TM, Pamer E, Knauf J, Ghossein R, Joyce JA, Fagin JA. Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression. PLoS One. 2013; 8(1): e54302

120. van Heijst JW, Ceberio I, Lipuma LB, Samilo DW, Wasilewski GD, Gonzales AM, Nieves JL, van den Brink MR, Perales MA, Pamer EG. Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation. Nat Med. 2013 Mar; 19(3):372-7.

121. Scher JU, Sczesnak A, Longman RS, Segata N, Ubeda C, Bielski C, Rostron T, Cerundolo V, Pamer EG, Abramson SB, Huttenhower C, Littman DR. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. Elife. 2013 Nov 5; 2:e01202.

122. Samstein M, Schreiber HA, Leiner IM, Susac B, Glickman MS, Pamer EG. Essential yet limited role for CCR2+ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming. Elife. 2013 Nov 12; 2:e01086.

123. Stein RR, Bucci V, Toussaint NC, Buffie CG, Ratsch G, Pamer EG, Sander C, Xavier JB. Ecological modeling from time-series inference: insight into dynamics and stability of intestinal microbiota. PLoS Comput Biol. 2013 Dec: 9(12): e1003388.

BOOK CHAPTERS AND REVIEWS:

1. Pamer EG, Bevan MJ, Lindahl KF. Do nonclassical, class Ib MHC molecules present bacterial antigens to T cells? Trends Microbiol. 1993 Apr;1(1):35-8.

2. Pamer EG. Cellular immunity to intracellular bacteria. Curr Opin Immunol. 1993 Aug;5(4):492-6.

3. Pamer EG. Immune response to Listeria monocytogenes. Host Response to Intracellular Pathogens. Edited by S.H.E. Kaufmann, R.G. Landes Company, and Biomedical Publishers. 1993; p.131-142.

4. Busch D, and Pamer EG. Assays for murine cytolytic T lymphocytes. Methods in Immunology. Edited by S.H.E. Kaufmann, Academic Press. 1997.

5. Pamer EG, Sijts AJ, Villanueva MS, Busch DH, and Vijh S. MHC class I antigen processing of Listeria monocytogenes proteins: implications for dominant and subdominant CTL responses. Immunol Rev. 1997 Aug; 158:129-36.

6. Grewal IS, Borrow P, Pamer EG, Oldstone MB, and Flavell RA. The CD40/CD154 system in anti-infective host defense. Curr Opin Immunol. 1997 Aug; 9(4):491-7.

7. Pamer E, Cresswell P. Mechanisms of MHC class I—restricted antigen processing. Annu Rev Immunol. 1998; 16:323-58.

8. Pamer EG. Cell-mediated immunity: the role of bacterial protein secretion. Curr Biol. 1998 Jun 18; 8(13):R457-60.

9. Vijh, S., and E.G. Pamer EG. The cell biology and immune response to Listeria monocytogenes, an intracellular pathogen. Intracellular Bacteria as Live Recombinant Vaccine Vectors. Edited by Yvonne Paterson, John Wiley & Sons, Inc. New York, New York. 1998.

10. Pamer EG. Antigen presentation in the immune response to infectious diseases. Clin Infect Dis. 1999 Apr;28(4):714-6.

11. Busch DH, Vijh S, and Pamer EG. Using Listeria monocytogenes for immunologic studies. Current Protocols in Immunology. Edited by Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM and Strober W. John Wiley & Sons, New York. 1999.

12. Pamer EG. The role of CD1-restricted T cells in infectious diseases. Trends Microbiol. 1999 Jan;7(1):13.

13. Finelli A, Kerksiek KM, Allen SE, Marshall N, Mercado R, Pilip I, Busch DH, and Pamer EG. MHC class I restricted T cell responses to Listeria monocytogenes, an intracellular bacterial pathogen. Immunol Res. 1999; 19(2-3):211-23.

14. Kerksiek KM, Pamer EG. T cell responses to bacterial infection. Curr Opin Immunol. 1999 Aug; 11(4):400-5.

15. Kerksiek KM, Pamer EG. MHC class Jb-restricted T cell responses to Listeria monocytogenes infection. Immunobiology. 1999 Dec; 201(2):205-9.

16. Busch DH, and Pamer EG. T lymphocyte dynamics during Listeria monocytogenes infection. Immunology Letters. 1999; 65:93-98.

17. Busch DH, Kerksiek K, Pamer EG. Processing of Listeria monocytogenes antigens and the in vivo T-cell response to bacterial infection. Immunol Rev. 1999 Dec; 172:163-9.

18. Finelli A, and Pamer EG. Immune and inflammatory responses to Listeria monocytogenes infection, In: V. Fischetti, R. Novick, J. Ferretti, D. Portnoy and J. Rood (ed.), Gram Positive Pathogens. ASM Press, Washington, D.C. 2000; Chap50:480-487.

19. Ahmed R, Lanier JG, and Pamer EG. Immunological memory and infection. In: S.H.E. Kaufman, A. Sher, and R. Ahmed (Ed.), Immunology of Infectious Diseases. ASM Press, Washington, D.C. 2001; Chap13:175-189.

20. Busch DH, Vijh S, Pamer EG. Animal model for infection with Listeria monocytogenes. Curr Protoc Immunol. 2001 May; Chapter 19:Unit 19.9.

21. Lauvau G, and Pamer EG. CD8 T cell detection of bacterial infection: Sniffing for formyl peptides derived from Mycobacterium tuberculosis. Journal of Experimental Medicine. 2001; 193:F35-39.

22. Tuma RA, Pamer EG. Homeostasis of naive, effector and memory CD8 T cells. Curr Opin Immunol. 2002 Jun; 14(3):348-53.

23. Wong P, Pamer EG. CD8 T cell responses to infectious pathogens. Annu Rev Immunol. 2003; 21:29-70. Epub 2001 Dec 19.

24. Serbina N, Pamer EG. Immunology. Giving credit where credit is due. Science. 2003 Sep 26; 301(5641):1856-7.

25. Serbina N, Pamer EG. Quantitative studies of CD8+ T cell responses during microbial infection. Curr Opin Immunol. 2003 Aug; 15(4):436-42.

26. Lara-Tejero M, Pamer EG. T cell responses to Listeria monocytogenes. Curr Opin Microbiol. 2004 Feb; 7(1):45-50.

27. Ploss A, and Pamer EG. Memory. In: S.H.E. Kaufmann (Ed.) Novel Vaccination Strategies. WILEY-VCH, Weinheim, New York, 2004; pp.73-88.

28. Pamer EG. Immune responses to Listeria monocytogenes. Nat Rev Immunol. 2004 Oct; 4(10): 812-823.

29. Pamer EG, and Glickman M. Cell-mediated defense against infection. In: Mandell GL, Bennett JE, and Dolin R (Ed.). Principles and Practice of Infectious Diseases. 6th Edition. Elsevier/Churchill Livingston, New York. 2005; Chap9.

30. Ploss A, and Pamer EG. Immunologic Memory. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Meyers RA (Ed). WILEY-VCH Verlag GmbH & Co., Weinheim, 2005; 383-483.

31. Rivera A, Hohl T, Pamer EG. Immune responses to Aspergillus fumigatus infections. Biol. Blood Marrow Transplant. 2006 Jan; 12(1 Suppl 1):47-9.

32. Hohl TM, Rivera A, and Pamer EG. Immunity to fungi. Curr Opin Immunol. 2006 Aug; 18(4):465-72.

33. Hohl TM, Pamer EG. Cracking the fungal armor. Nat Med. 2006 Jul; 12(7):730-2 34. Pamer EG, and Paul W. Immune responses to intracellular bacterial infections.

Fundamental Immunology. Lippincott Williams & Wilkins. 2006. 35. Pamer EG. Immune responses to commensal and environmental microbes. Nat Immunol.

2007 Nov; 8 (11):1173-8. 36. Serbina NV, and Pamer EG. Role of dendritic cells in the innate response to bacteria.

Advances in Molecular and Cellular Microbiology. 2007; Chap55:99-118. 37. Serbina NV, Jia T, Hohl TM, Pamer EG. Monocyte-mediated defense against microbial

pathogens. Annu Rev Immunol. 2008; 26:421-52. 38. Pamer EG. Immune responses to intracellular bacteria. Fundamental Immunology.

Lippincott Williams & Wilkins. 2008; Chap37:1165-1181. 39. Serbina NV, Pamer EG. Coordinating innate immune cells to optimize microbial killing.

Immunity. 2008 Nov 14;29(5):672-4. 40. Pamer EG. TLR polymorphisms and the risk of invasive fungal infections. N Engl J Med.

2008 Oct 23; 359(17):1836-8. 41. Rivera A, Pamer EG. CD4+ T cell responses to Aspergillus fumigatus. Aspergillus

fumigatus and Aspergillosis. Edited by Latge JP, and Steinbach WJ. ASM Press, Washington, DC. 2009.

42. Pamer EG. Tipping the balance in favor of protective immunity during influenza virus infection. Proc Natl Acad Sci USA. 2009 Mar 31;106(13):4961-2.

43. Jia T, Pamer EG. Immunology. Dispensable but not irrelevant. Science. 2009 Jul 31;325(5940):549-50.

44. Jarchum I, Pamer EG. Regulation of innate and adaptive immunity by the commensal microbiota. Curr Opin Immunol. 2011 Jun; 23(3):353-60.

45. Serbina NV, Shi C, Pamer EG. Monocyte-Mediated Immune Defense Against Murine Listeria monocytogenes Infection. Adv Immunol. 2012; 113:119-34.

46. Kinnebrew MA, Pamer EG. Innate immune signaling in defense against intestinal microbes. Immunol Rev. 2012; Jan; 245(1):113-31.

47. Littman DR, Pamer EG. Role of the commensal microbiota in normal and pathogenic host immune responses. Cell Host & Microbe. 2011 Oct 20; 10(4):311-23.

48. Shi C, Pamer EG. Monocyte recruitment during infection and inflammation. Nat Rev Immunol. 2011 Oct 10; 11(11):762-74.

49. O’Garra A, Pamer EG. Editorial overview. Curr Opin Immunol. 2012 Aug;24(4):361-3. 50. Ubeda C, Pamer EG. Antibiotics, microbiota, and immune defense. Trends Immunol. 2012

Sep;33(9):459-66. 51. Ubeda C, Pamer EG. Securing the border: lymphotoxin, IL-23 and IL-22 keep out the bad

guys and ‘fatten’ the homeland. Nat Immunol. 2012 Oct;13(10):940-1. 52. van Heijst JW, Pamer EG. Radical host-specific therapies for TB. Cell. 2013 Apr

25;153(3):507-8. 53. Taur Y, Pamer EG. The intestinal microbiota and susceptibility to infection in

immunocompromised patients. Curr Opin Infect Dis. 2013 Aug 26(4):332-7. 54. Pamer EG. Cuffed and exposed—perp-walking bradyrhizobium. N Engl J Med. 2013 Aug

8;369(6):572-4. 55. Buffie CG, Pamer EG. Microbiota-mediated colonization resistance against intestinal

pathogens. Nat Rev Immunol. 2013 Nov; 13(11):790-801. 56. Pamer EG. Fecal microbiota transplantation: effectiveness, complexities, and lingering

concerns. Mucosal Immunol. 2014 Jan 8.  INVITED PRESENTATIONS (Since 2005):

2/9/2005 “CD8 T cell priming and memory.” Keynote Address: Immunology of Malaria Infections at Johns Hopkins Malaria Research Institute; Baltimore, MD.

4/4/2005 “Innate and adaptive immune responses to Listeria

monocytogenes infection” Microbiology and Immunology Seminar Series at AECOM; Bronx, NY.

4/12/2005 “Innate and adaptive immune responses to Listeria

monocytogenes infection” Pediatric Grand Rounds at NYPH; New York, NY.

4/14/2005 “Innate and adaptive immune responses to Listeria

monocytogenes infection” Department of Immunology Seminar Series at the University of Pittsburgh; Pittsburgh, PA.

5/12/2005 “CD4 T cells in Aspergillus induced asthma” SPAR Annual

Meeting; San Francisco, CA 5/18/2005 “Innate immune polymorphisms in allogeneic bone marrow

transplant recipients” Human Immunology Conference, Dana Foundation; New York, NY

8/8/2005 “Innate immune responses to bacterial and fungal infections” Fall ITIC Molecular Biology Workshop; McLean, VA

9/17/2005 “Generation of memory CD8 T cells during bacterial infection”

2005 MPIIER Conference; Cleveland, OH 9/19/2005 “Immune response to Listeria monocytogenes infection”

University of Washington School of Medicine Symposium; Seattle, WA

9/27/2005 “TNF and iNOS producing DC’s in defense against bacterial

infection” 2nd International Dendritic cells at the Host-Pathogen Interface Conference; Airlie, VA

11/11/2005 “Cellular immune response – Th1/Th2 paradigm change and

immune reconstitution following antineoplastic therapy and stem cell transplantation” Houston, TX

12/2/2005 “T cell responses to A. fumigatus infection” Cold Spring Harbor,

NY

1/6/2006 “Immune response to Aspergillus fumigatus infection” Pathogen-Host Standoff: Persistent and Latent Infection Keystone Symposia; Keystone, Colorado

1/19/2006 “Regulation of leukocyte trafficking during infection”

Chemokines and Chemokine Receptor Keystone Symposia; Snowbird, Utah

1/25/2006 “Immune responses to infection with Aspergillus fumigatus”

Progress in Tuberculosis Research, Department of Microbiology & Immunology Symposium, AECOM; Bronx, NY

2/16/2006 “Infectious diseases in transplant patients” 2006 Tandem BMT

Meetings; Honolulu, HA 3/3/2006 Advisory Board for the Clinical Trial of Myeloid Progenitors in

Chemotherapy Induced Neutropenia, Cellerant Therapeutics; San Francisco, CA

4/6/2006 “Immune responses to Fungal Infection” Baylor School of

Medicine; Houston, TX

5/14/2006 “Immune responses to Listeria monocytogenes infection” American Association of Immunologists Annual Meeting; Boston, MA

6/2/2006 “Immune responses to bacterial and fungal infections” 7th

Annual Meeting on Infection Immunity: Cellular mechanisms in host-pathogen interaction; Elsinore, Denmark

9/20/2006 “CCR2-mediated signaling in response to bacterial infection”

Gordon Research Conferences Chemotactic Cytokines Conference; Aussois, France

10/13/2006 “Innate and Adaptive Immunity to Aspergillus” 44th Annual Infectious Disease Society of America Meeting; Toronto, Canada

11/10/2006 “Immune responses to the inhaled fungal pathogen Aspergillus

fumigatus” Joint Society for Leukocyte Biology and the International Endotoxin and Innate Immunity Society Meeting; San Antonio, TX

11/16/2006 “Immunity to Aspergillus fumigatus” 6th Louis Pasteur

Conference on Infectious Diseases; Paris, France 2/14/2007 “Immunity to Aspergillus fumigatus” 2nd International

Symposium on Immune Surveillance, Its cellular and molecular basis, regulation and maintenance; Tokyo, Japan

3/1/2007 “Host Pathogen Interaction” 5th Mini-symposium, Immune

responses to respiratory fungal infection; Braunschweig, Germany

3/6/2007 “Immune responses to respiratory fungal infection” Faculty

Seminar Series; UC of Berkeley, CA 6/21/2007 “Innate and adaptive immune responses to respiratory fungal

infection” Biodefense Immune Modeling Summer School; Pittsburgh, PA

8/22/2007 “Immunology of bacterial and fungal diseases” 13th International

Congress of Immunology; Rio de Janeiro 10/12/2007 “Immune responses to fungal infection” 40th Annual Meeting of

the Society for Leukocyte Biology Inflammation, Innate Immunity & Cancer; Cambridge, MA

10/28/2007 “Innate and T cell responses to Aspergillus fumigatus infection”

3rd Trends in Medical Mycology; Torino, Italy 12/3/2007 “Innate and adaptive immune responses to microbial pathogens”

U of Chicago Committee on Immunology Seminar Series; Chicago, IL

1/10/2008 “Immunology Seminar Series” at Mt. Sinai School of Medicine

Immunology Institute; New York City, NY 2/2/2008 “Innate and Adaptive Immune Responses to Bacterial and

Fungal Infections” Hot Springs Harbor Symposium; Beppu, Japan

3/12/2008 “Innate and adaptive immune responses to microbial pathogens”

University of Pennsylvania; Philadelphia, Pennsylvania 3/19/2008 “Innate and adaptive immune responses to Aspergillus fumigatus

infection” University of Michigan; Ann Arbor, Michigan 4/9/2008 “Trafficking & differentiation of CD4 T cells during respiratory

infections” AAI Annual Meeting; San Diego, CA

4/14/2008 “Immune defense against bacterial and fungal pathogens” Highlights in Immunology; Rehovot, Israel

5/1/2008 “Innate Immune Response to Intestinal Bacteria” 4th Annual

MVM Retreat 4th Annual MVM Retreat (U. of Pittsburgh); Pittsburgh, Pennsylvania,

5/23/ 2008 “Listeria and DCs” Columbia University Immunology Lecture;

NYC, NY 6/23/2008 “Antibiotics and Innate Immune Defense against Vancomycin

resistant Enterococcus Infections” Keynote Speaker: Immunocompromised Host Society (ICHS); Thessaloniki, Greece

10/8/2008 “Innate Immune Defense Against Intestinal Bacteria” 2nd

Journée de la Recherche Biomédicale (Translational Research Day); Institut Pasteur in Paris, France

10/10/2008 “TLR-Signaling and Intestinal Immune Tone: Role of

Commensal Complexity” Third Bernard Halpern Symposium of Immunology; Paris, France

10/29/2008 “Innate Immune Responses to Intestinal Bacteria” Yale University; New Haven, CT 10/31/2008 “Innate Immune Responses to Intestinal Bacteria” New York University Immunology Seminar; New York, NY 1/8/2009 “Innate Immune Defense in the Intestine” Stanford University; Stanford, CA 1/12/2009 “Innate Immune Defense in the Intestine” SUNY Stony Brook; Stony Brook, NY

2/20/2009 “Innate Immune Defense against Intestinal Microbes” 2nd International Conference: Immunological Self Recognition and its Disorders; Kyoto, Japan

3/4/2009 “Monocyte recruitment during Listeria infection” Foundation des

Treilles; Haupt-Var, France

3/19/2009 “Innate immune activation by intestinal commensal bacteria” Rocky Mt. Labs; Hamilton, MT

4/23/2009 “Innate immune defense against intestinal bacteria” The Kunkel

Meeting; Rockefeller University, NY

5/18/2009 “Microbiology and Immunology at Mucosal Surfaces” ASM Division E Symposium; Philadelphia, PA

6/19/2009 “Innate immune defense against intestinal microbes” Technical

University of Munich; Munich, Germany

7/17/2009 “Mucosal innate defense against intestinal bacteria” Annual International Symposium of the DFG; Würzburg, Germany

9/9/2009 “TLR-mediated induction of RegIIIγ in the small intestine” 7th

Awaji International Forum on Infection and Immunity; Awaji, Japan

9/13/2009 “Enhancing intestinal immune defense against highly antibiotic resistant bacteria” 49th Inter-science Conference on Antimicrobial Agents and Chemotherapy (ICAAC); San Francisco, CA

9/30/2009 “Innate immune responses to bacterial infection” University of

Vermont; VT 10/21/2009 “Innate immune defense against intestinal bacteria” Immunology

Interest Group Seminar Series; NIH, Bethesda, MD 10/30/2009 “Innate immune defense against intestinal bacteria” 47th Annual

Infectious Diseases Society of America (IDSA); Philadelphia, PA

11/13/2009 “Innate Immunity and the microbiome” Microbiome, Infections,

and Cancer Mini Symposium; NCI-Frederick, NIH 2/1/2010 “Innate Immune Defense against Intestinal Bacteria” University

of Virginia, Charlottesville; VA 2/28-3/3/2010 “Monocyte emigration from bone marrow during bacterial

infection” Weizmann Institute of Science; Tel Aviv, Israel 4/8/2010 “Mesenchymal stem cells: Gatekeepers for bone marrow

monocytes during infection” Harvard University; Boston, MA 4/18/2010 “Innate immune defense against intestinal bacteria” Columbia

University; New York, NY

4/22/2010 “Immune responses to intestinal bacteria” University of Pittsburgh, Pittsburgh, PA

4/26/2010 “Innate and adaptive immune responses to respiratory fungal

infection” University of California at San Francisco; San Francisco, CA

5/10-13/2010 “Innate immune responses to bacterial infection” International Symposium "Inflammation-associated Pathogenesis: Inflammation and Cancer" Bavaria, Germany

5/14/2010 “Antibiotics, Microbiota and Intestinal Immunity” University of

Chicago; Chicago, IL 5/20/2010 “Antibiotics, Microbiota and Intestinal Immunity” LPD Seminar

Series; NIH, Bethesda, MD 5/24-25/2010 “Mucosal immune defense against highly antibiotic-resistant

intestinal bacteria” ASM Meeting; San Diego, CA 7/7-8/2010 “The intestinal microbiota and innate immune defense against

bloodstream infections” Technical University of Munich; Germany

9/23-24/2010 “Antibiotic effects on the intestinal microbiota and susceptibility

to infection during cancer treatment”. National Cancer Institute

Conference on Immunity, Inflammation and Cancer, NIH, Bethesda, MD

9/26-30/2010 “Inflammatory monocyte trafficking during bacterial infection”.

DC2010: Forum on Vaccine Science, Lugano, Switzerland. 10/1/2010 “Innate immune defense against intestinal bacteria”. Department

of Microbiology and Immunology, University of Zurich, Zurich, Switzerland.

11/7-10/2010 “Microbiota and innate immune defenses against intestinal

infection”. Cold Spring Harbor Asia conference on Frontiers of Immunology in Health and Disease, Suzhou, China.

1/23-26/2011 “Antibiotics, microbiota and immune defense against intestinal

bacteria” and Chairperson of session entitled “Intestinal Commensal Microbes: Protagonists, Antagonists and Extras”. The 50th Midwinter Conference of Immunologists, Pacific Grove, CA.

2/8/2011 “Innate immune defense against intestinal pathogens”. Public

Health Research Institute, University for Medicine and Dentistry of New Jersey, Newark, NJ.

3/22-26/2011 “Role of commensal microbiota in regulating lymphocyte

activation and function”. 2011World Immune Regulation Meeting. Davos, Switzerland.

4/12/2011 “Antibiotics, microbiota and immune defense against intestinal

bacteria” Distinguished Speaker, Department of Microbiology, University of California, Santa Cruz, Santa Cruz, CA.

4/14-16/2011 “Massive changes in the intestinal microbiota in mice and

humans following antibiotic treatment and during allogeneic hematopoietic stem cell transplantation”. Nature Conference on Microbiota and Mucosal Immunology: The Interface in Health and Disease. San Francisco, CA.

5/6/2011 “Enhancing mucosal resistance to colonization with antibiotic-

resistant pathogens”. Department of Immunology, Pasteur Institute, Paris, France.

6/30-7/1/2011 “Intestinal microbiota, Toll-like receptor signaling and innate

immune defense against microbial pathogens.” 5th Miltenyi Biotec Symposium, Paris, France.

7/8/2011 “Intestinal innate immune defense in health and disease: Impact

of the gut microbiota”. Justin Paswell Symposium, Weizmann Institute, Rehovot, Israel.

7/27/2011 “The role of intestinal microbiota in the development of antibiotic-resistant infections.” Microbial Adhesion and Signal Transduction Gordon Conference, Newport, Rhode Island.

9/18/2011 “Impact of antibiotic treatment and allogeneic hematopoietic

stem cell transplantation on the intestinal microbiota of mice and humans.” International Congress for Antimicrobial Agent and Chemotherapeutics, Chicago, Illinois.

9/24/2011 “Inflammatory monocyte trafficking during bacterial infection.”

Annual Meeting of The Society for Leukocyte Biology, Kansas City, MO.

10/21/2011 “The intestinal microbiome, innate immunity and intestinal

resistance to colonization and infection.” Annual Meeting of the Infectious Diseases Society of America, Boston, MA.

11/10/2011 “Impact of antibiotic treatment and allogeneic hematopoietic

stem cell transplantation on the intestinal microbiota of mice and humans.” Keynote Address, Annual Retreat of Institute for Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany

12/14/2011 “Antibiotics, the intestinal microbiota and innate immune

defense against infection.” Keynote Address, Annual Meeting of the Dutch Society for Immunology, Noordwijkerhout, Netherlands.

1/5/2012 “Antibiotics, the intestinal microbiota and innate immune

defense against infection.” Immunology Program Speaker, New York University, New York, NY.

1/19/2012 “Antibiotics, the intestinal microbiota and innate immune

defense against infection.” Immunobiology Program Seminar Series, Yale School of Medicine, New Haven, CT.

3/23/2012 “Antibiotics, the intestinal microbiota and innate immune defense against infection.” The University of Arizona’s, Department of Immunobiology “Graduate Student Seminar Series”.  

4/16/2012 “The intestinal microbiota and defense against infection”. Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

5/15/2012 “Antibiotic effects on the intestinal microbiota of mice and

humans.” Interacademies Symposium, Académie des sciences, German National Academy of Sciences Leopoldina and The Royal Society, Paris, France.

5/19-22/2012 “New Perspectives on Immunity to Infection”. EMBO / EMBL Symposium, Heidelberg, Germany.

5/23/2012 “Antibiotics, microbiota and susceptibility to intestinal

infection.” Spring 2012 Microbiology Seminar Series. University of Pennsylvania, Philadelphia, PA.

7/8-13/2012 “Antibiotics, the intestinal microbiota and innate immune defense against infection.” Microbial Toxins & Pathogenicity 2012 Gordon Research Conference. Waterville Valley, NH

9/10-13/2012 “Impact of the Intestinal Microbiota on Mucosal Defense

Against Pathogenic Bacteria” From the Laboratory to the Clinic: Towards New Treatment of Chronic and Acute Inflammatory Diseases Seminar. Trinity College, Oxford London.

9/20-21/2012 “Intestinal microbiota, Toll-like receptor signaling and innate

immune defense against microbial pathogens.” COBRE EAC Meeting. University of Vermont. Burlington, VT.

10/3-6/2012 “Immune dysregulation in the intestine”. 15th Biennial Meeting

of the European Society for Immunodeficiencies, Florence, Italy.

1/15-20/2013 “Innate Immune Responses to Intestinal Bacteria” Keystone Symposia on Emerging Topics in Immune System Plasticity: Cellular Networks, Metabolic Control and Regeneration. Santa Fe, New Mexico.

1/28-2/8/2013 “Microflora & Mucosal Immunity” Advanced Immunology

Course. Amsterdam, The Netherlands.

2/10-15/2013 “Microbiota-Mediated Resistance to Infection by Intestinal Pathogens.” Keystone Symposia on The Gut Microbiome: The Effector/Regulatory Immune Network. Taos, New Mexico.

2/19-24/2013 “Monocytes and defense against pulmonary infections.”

Keystone Symposium on Myeloid Cells: Regulation and Inflammation. Keystone, Colorado.

3/13-18/2013 “Ly6Chi Monocytes and Immune Defense Against

Mycobacterium Tuberculosis Infection.” Keystone Symposium on Tuberculosis: Understanding the Enemy. Whistler, British Columbia, Canada.

4/9/2013 “Microbiota-Mediated Resistance to Infection by Intestinal

Pathogens.” Seminar at Harvard Medical School, Department of Microbiology and Immunology. Boston, MA.

4/18/2013 “Microbiota-Mediated Resistance to Infection by Intestinal

Pathogens.” Seminar at the Immunology and Microbial Science Affinity Group, Scripps Research Institute. La Jolla, CA

4/22/2013 “Microbiota and Innate Immune Defense Against Intestinal Infection.” Microbiology Immunology and Cancer Biology Program Seminar Series, University of Minnesota. Minneapolis, MN.

4/25-28/2013 “Microbiota and Innate Immune Defense Against Intestinal

Infection.” 2013 Clinical Immunology Society Annual Meeting: Regulation and Dysregulation of Immunity. Miami, FL.

5/2-3/2013 “Monitoring and Manipulating the Intestinal Microbiota to

Prevent Systemic Infections.” Fecal Microbiota for Transplantation: Scientific and Regulatory Issues. Center for Biologics, Evaluation and Research (FDA) and the National Institute for Allergy and Infectious Diseases (NIH). Bethesda, MD.

5/7/2013 “Microbiome-mediated Protection Against Antibiotic Resistant

Bacterial Pathogens.” Hot Topics in Infectious Diseases, Infectious Diseases Society of New York, Albert Einstein College of Medicine. Bronx, NY

5/12-14/2013 “Intestinal Microbiota and Immune Defense Against Infection.”

Cell Symposia: Microbiome and Host Health. Lisbon, Portugal. 5/17/2013 “Antibiotics, the Microbiota and Defense Against Intestinal

Bacterial Infections.” Seattle Children’s Research Institute Seminar Series. Seattle, WA.

5/20/2013 “Antibiotics, the Microbiota and Defense Against Intestinal

Bacterial Infections.” Immunology Seminar at the University of Washington Department of Immunology Seminar Series. Seattle, WA.

5/31/2013 “Intestinal Microbiota and Immune Defense Against Infection.”

78th Cold Spring Harbor Symposium on Quantitative Biology: Immunity and Tolerance. Cold Spring Harbor, NY.

6/28/2013 “Antibiotics, the Intestinal Microbiota and Resistance to

Infection.” Infectious Diseases Grand Rounds, North Shore Long Island Jewish Health System. Manhasset, NY.

7/21-25/2013 “Antibiotics, the Intestinal Microbiota and Resistance to

Infection.” 5th Federation of European Microbiological Societies Congress of European Microbiologists. Leipzig, Germany.

9/13-15/2013 “Monitoring and Manipulating the Intestinal Microbiota to

Prevent Systemic Infections.” 4TH International Human Microbiome Congress. Hangzhou, China.

9/20/2013 “Microbiota-mediated Defense Against Antibiotic-Resistant Infections.” Wellcome Institute Sanger Institute. Cambridgeshire, UK.

9/25/2013 “Microbiota-mediated Defense Against Antibiotic-Resistant

Infections.” 2013 Annual Meeting of the German Society for Hygiene and Microbiology. Rostock, Germany.

10/10-12/2013 “Inflammatory Monocyte Trafficking in Response to Pulmonary

Infection.” 27th Annual Meeting of the European Macrophage and Dendritic Cell Society: Myeloid Cells: Microenvironment, Microorganisms and Metabolism. Erlangen, Germany.

10/22-26/2013 “Microbiota and Innate Immune-Mediated Defense Against

Clostridium Difficile Infection.” 8th International Conference on the Molecular Biology and Pathogenesis of the Clostridia. Queensland, Australia.

11/1/2013 “Microbiome-mediated defense against bacterial infection.”

Interurban Clinical Club Meeting, MSKCC. New York, NY. 11/12/2013 “Antibiotics, the Microbiota, and Defense against Bacterial

Infection.” Weill Cornell Medicine Grand Rounds. New York Presbyterian/Weill Cornell Medical Center. New York, NY.

11/13/2013 “Antibiotics, the Microbiota, and Defense against Bacterial

Infection.” Medical Grand Rounds, St. John’s Episcopal Hospital. Far Rockaway, NY.

12/2-4/2013 “Mobilisation of Cells from the Bone Marrow in Response to

Distant Infection.” Invited Speaker for Session: “Migration: Tolerance vs. Immunity.” British Society for Immunology Congress 2013. Liverpool, UK.

12/12/2013 “Antibiotics, the Microbiota, and Defense against Bacterial

Infection.” Research Seminar Series, Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center. New York, NY.

1/31/2014 “Inflammatory monocytes and immune defense against

Mycobacterium tuberculosis infection.” Immunobiology Celebrates 25 years: 1988-2013, Past, Present and Future. Yale School of Medicine, New Haven, CT.

3/5-7/2014 “Antibiotics, microbiota, and the gut.” Enterococcal Virulence,

8th International Symposium on Antimicrobial Resistance (ISAR), 4th ASM Conference on Enterococci, Cartagena, Colombia.

3/11-13/2014 “The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation.” The Impact of the Microbiome on Cancer, Keystone Symposium on Inflammation, Infection, and Cancer. Whistler, British Columbia.

3/18/2014 Microbiome-Opportunities and Challenges, 2014 Gordon

Research Conference on New Antibacterial Discovery and Development, Ventura, CA.

3/19-20/14 Departmental Seminar Series, Department of Microbiology and

Immunology, UT Health Science Center, San Antonio, TX. 3/27/14 2013-2014 Immunology and Cancer Biology Seminar Series,

Cedars-Sinai Medical Center, Los Angeles, CA. 4/4-6/14 “Inflammation and infectious diseases.” The Yin and Yang of

Inflammation, Trudeau Institute, High Peaks Resort, Lake Placid, NY.