oral medicine-yousef nasrawi
TRANSCRIPT
ORAL MEDICINE
Done By YOUSEF NASRAWI
* All the slides and images was given by Dr.aceil al-khatib in the lectures
CONTANTS
. White lesions
. Bacterial infections
. Viral infections
. Fungal infections
. Oral ulcerations
. Salivary glands
. Mucocutaneous diseases
. Methods of investigations
White Lesions
Candidal leukoplakia
Leukoplakia of the floor of the mouth
Erythroplakia
Actinic chelitis
Lichen planus
Benign leukoplakia
Malignant leukoplakia
VEL scope
Oral brush biopsy
Bacterial Infections
ANUG
Cancrum oris (noma)
Primary syphilis
Secondary syphilis
Condylomata lata (sec. syphilis)
Tertiary syphilis
Gumma on hard palate
Early congenital syphilis
Late congenital syphilis
Gonococcal Ophthalmia Neonatorum
Gonorrhea The main presentation is having sore throat or
pus discharge from gingiva
Reiter’s syndrome
Tuberculosis
Actinomycosis
Viral Infections
Primary herpetic gingivostomatitis
Recurrent Herpes
Herpetic whitlow
Varicella Zoster infections(Chicken pox)
Varicella zoster infections(Shingles)
Ramsay hunt syndrome
Infections mononucleosis
Burkitt’s Lymphoma
Hairy leukoplakia
Hand foot and mouth disease
Herpangina
Paramyxovirus infections(measles)
Mumps
Human papilloma virus
Fungal Infections
Candida albicans (IMPORTANT)
Pseudo membranous candidosis
Infant with candidosis
Hyper-plastic candidosis
Erythematous candidosis
Median Rhomboid Glossitis
Denture stomatitis (Type I,II,III)
Angular cheilitis
Chronic mucocutanuoes candidosis
Mucormycosis
Oral Ulcerations
Traumatic ulcer
Factitious ulcer
Minor aphthous ulceration
Major aphthous ulceration
Herpetiform ulceration
Histology of aphthous ulceration: (a) Aphthous ulcer of the lip defecting the epithelial layer (HE, 100).
(b) Magnified feature of the ulcer edge of the epithelial layer. The epithelial cells are surrounded by inflammatory infiltrates like
“Rosetta formation.”
Ulcerative Colitis
MAGIC syndrome
Sweet’s syndrome
Behcet’s disease
Pathergy Test (behcet’s disease)
Salivary Gland Disorders
Sublingual salivary glands
Submandibular glands
Parotid gland
Sialometry
Carlson-Crittenden Collector
Plain radiograph of the submandibular region in AP: (A) and lateral oblique (B) projection showing soft tissue
swelling associated with a small calculus (arrow) visible on lateral oblique view taken with depressed tongue
Axial CT scan of the neck showing a left parotid pleomorphic adenoma
CT scan of the left enlarged parotid gland
Accessory parotid gland with ectopic fistulous duct: The child was managed surgically by internalisation of the duct to
open into the buccal mucosa and excision of pre-aural appendages.
Ultrasound showing swollen left and normal right submandibular gland
Conventional Sialography of submandibular gland
(A) and parotid glands (B) showing ductal system
Snow Storm appearance (sjogren’s syndrome)
Scintigraphy
MRI
Sialendoscopy
Sialolithiasis
Bacterial sialdenitis
Acute parotitis
Viral sialadenitis (mumps)
Sialosis (Sialadenosis)
Necrotizing Sialometaplasia
Sarcodosis
Xerostomia
Sjogren’s syndrome (SS)
Schirmer Test (for SS)
Sialorrhea (Ptyalism)
Inflammatory Overgrowths
Fibrous epulis
Pyogenic granuloma
Pregnancy epulis
Peripheral giant cell granuloma
Fibroepithelial Polyp
Denture granuloma
Heck’s disease
Heamangioma
Lymphangioma
Lymphangioma on the palate A very unique case of congenital intra-oral lymphangioma
circumscriptum in a 10-year-old boy presented with a predominantly-unilateral, grouped, deep-seated vesicles
some of which were bloody, confined to the right posterior half of the hard palate.
White sponge naevus
White sponge naevus
Pachyonychia congenita
Benign Intraepithelial Dyskeratosis (Witkop’s)
Dyskeratoses congentia
Tylosis palmoplantar keratoderma
Darier’s disease
Squamous cell papilloma
Traumatic keratosis
Nicotinic stomatitis
Amalgam tattoos
Mucoctaneous Diseases I
Lichen planus
Lichen planus (Koebner phenomenon)
Non erosive LP
Erosive LP
Histopathlogy of LP
that show the lymphocytic band like infiltrate.
GVHD
Chronic ulcerative stomatitis
Pemphigus vulgaris
Pemphigus vegetants
Pemphigus foliaeous
Paraneoplastic pemphigus
Hailey-Hailey disease
Nikolsky sign
Histopathlogy for pemphegus A) Light microscopy studies of an early bulla reveal subepidermal
blistering with a superficial dermal inflammatory infiltrate rich in eosinophils. The cavity of the bulla contains nets of fibrin
andsome eosinophils and neutrophils. (B) Direct
immunofluorescence studies from 'perilesional' skin shows linear continuous deposits of IgG along the dermoepidermal
junction. (C) Indirect immunofluorescence studies using NaCl-
split skin shows autoantibodies that bind to the epidermal side of the separation.
Mucoctaneous Diseases II
Bullous pemphigoid
Mucosal membrane pemphigoid
Antiepiligrin cicatrical pemphigoid (AECP)
Erythema multiforme
Epidermolysis bullosa
Epithelial peeling
Oral blood blisters
Systemic lupus erythromatosus
Discoid lupus
Morphoea
Systemic sclerosis
Systemic sclerosis
Methods of Investigations
Primary hyperparathyroidism
(Salt and pepper appearance)
Paget’s disease
Multiple myeloma
(Punched-out appearance)
Microscopic image of direct immunoflurescence using an anti-IgG antibody. The tissue is skin from a patient with
Pemphigus vulgaris.
Microscopic image of direct immunoflurescence using an anti-IgG antibody. The tissue is skin from a patient with
Pemphigoid lesion
Incisional biopsy
Excisional biopsy
Pleomorphic adenoma
(Incisional biopsy)
Melanoma
(Excisional biopsy)
Warts
(Excisional biopsy)
Oral brush biopsy
THE END