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    CARDIAC DISORDERSMs Hassen Zabala, RN, MAN

    July 22, 2013

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    HEART FAILURE

    Definition

    Heart failure is a condition in whichthe heart can no longer pump

    enough blood to the rest of thebody.

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    Causes, incidence, and risk factors

    Heart failure is present when: Your heart muscle cannot pump (eject) the blood out of the heart

    very well. This is called systolic heart failure.

    Your heart muscles are stiff and do not fill up with blood easily. Thisis called diastolic heart failure.

    As the heart's pumping action is lost, blood may back up inother areas of the body.

    The most common cause of heart failure is coronary artery

    disease (CAD), a narrowing of the small blood vessels thatsupply blood and oxygen to the heart.

    Heart failure can also occur when an infection weakens theheart muscle. This condition is called cardiomyopathy.

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    Other heart problems

    that may cause heart

    failure are:

    Congenital heart disease

    Heart attack

    Heart valve disease

    Some types of abnormal

    heart rhythms

    (arrhythmias)

    Other diseases that can

    cause or contribute to

    heart failure:

    Emphysema

    Overactive thyroid

    Severe anemia

    Underactive thyroid

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    Structure of the Heart

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    Circulation of the Heart

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    Symptoms

    Cough

    Fatigue, weakness,faintness

    Loss of appetite

    Need to urinate at night

    Pulse that feels fast orirregular, or palpitations

    Shortness of breathwhen active or afterlying down

    Swollen (enlarged) liveror abdomen

    Swollen feet and ankles

    Weight gain

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    Signs and tests

    Signs of heart failure:

    Fast or difficult breathing

    Irregular or fast heartbeat and abnormal heart sounds

    Leg swelling (edema)

    Neck veins that stick out (are distended)

    Sounds ("crackles") from fluid buildup in the lungs, heardthrough a stethoscope

    Swelling of the liver or abdomen

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    An echocardiogram (echo) is often the best testto diagnose, learn the cause of, and monitor

    heart failure.

    Other imaging tests are:

    Cardiac stress tests

    Heart catheterization

    MRI of the heart

    Nuclear heart scans

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    Echocardiogram Cardiac stress test

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    Cardiac catheterization MRI of heart

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    Nuclear heart scans

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    Lab tests:

    Check how well kidneys are working (BUN,

    creatinine, creatinine clearance, urinalysis)

    Look for a low blood count or anemia -- completeblood count (CBC)

    Test for brain natriuretic peptide (BNP)

    Watch sodium and potassium levels in blood

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    Treatment

    These medicines:

    Help the heart muscle pump better

    Keep blood from clotting

    Lower cholesterol levels

    Open up blood vessels or slow heart rate

    Replace potassium

    Rid body of excess fluid and salt (sodium)

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    The following surgeries and devices may berecommended for certain patients with heart

    failure:

    Coronary bypass surgery (CABG) and angioplasty mayhelp improve blood flow to the damaged or weakenedheart muscle.

    Heart valve surgery may be done if changes in a heartvalve are causing your heart failure.

    A pacemaker can help treat slow heart rates or helpboth sides of your heart contract at the same time.

    A defibrillator sends an electrical pulse to stop life-

    threatening abnormal heart rhythms.

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    END-STAGEHEART FAILURE

    Severe heartfailure occurswhen treatments

    no longer work. Intra-aortic

    balloon pump(IABP)

    Left ventricularassist device(LVAD)

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    VALVULAR HEART DISEASE

    Definition

    Heart valve disease occurswhen your heart's valves do

    not work the way they should.

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    What Are the Types of Valve Disease?

    Valvular stenosis. This occurs when a valveopening is smaller than normal due to stiff orfused leaflets. The narrowed opening may

    make the heart work very hard to pump bloodthrough it. This can lead to heart failure andother symptoms (see below). All four valvescan be stenotic (hardened, restricting blood

    flow); the conditions are called tricuspidstenosis, pulmonic stenosis, mitral stenosis oraortic stenosis

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    Valvular insufficiency. Also called

    regurgitation, incompetence or "leaky valve",this occurs when a valve does not close tightly.If the valves do not seal, some blood will leakbackwards across the valve. As the leak

    worsens, the heart has to work harder tomake up for the leaky valve, and less bloodmay flow to the rest of the body. Dependingon which valve is affected, the conditioned is

    called tricuspid regurgitation, pulmonaryregurgitation, mitral regurgitation or aorticregurgitation.

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    What Causes Valvular Heart Disease?

    Valve disease can develop before birth(congenital) or can be acquired sometime duringone's lifetime.

    Congenital valve disease. Most often affects theaortic or pulmonic valve.

    Bicuspid aortic valve disease is a congenital valvedisease that affects the aortic valve. Instead ofthe normal three leaflets or cusps, the bicuspid

    aortic valve has only two.

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    Acquired valve disease. Rheumatic fever is caused by an untreated bacterial infection

    (usually strep. throat). The heart valves become inflamed, theleaflets stick together and become scarred, rigid, thickened

    and shortened. This leads to mitral regurgitation. Endocarditis occurs when germs, especially bacteria, enter the

    bloodstream and attack the heart valves, causing growths andholes in the valves and scarring. This can lead to leaky valves.

    Mitral valve prolapse (MVP) is a very common condition,causes the leaflets of the mitral valve to flop back into theleft atrium during the heart's contraction.

    Other causes of valve disease include: coronary arterydisease, heart attack, cardiomyopathy (heart muscledisease), syphilis (a sexually transmitted disease),hypertension, aortic aneurysms, and connective tissuediseases.

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    What Are the Symptoms of Valve

    Disease?

    Shortness of breath and/or difficulty catchingyour breath.

    Weakness or dizziness.

    Discomfort in your chest. You may feel a pressureor weight in your chest with activity or whengoing out in cold air.

    Palpitations.

    Swelling of your ankles, feet or abdomen.

    Rapid weight gain. A weight gain of two or threepounds in one day is possible.

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    How Are Valve Diseases Diagnosed?

    After the physical exam, the doctor may order

    diagnostic tests. These may include:

    Echocardiography

    Transesophageal echocardiography

    Cardiac catheterization (also called an angiogram)

    Radionuclide scans

    Magnetic resonance imaging (MRI)

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    How Is Heart Valve Disease Treated?

    Medications Diuretics ("water pills")

    Antiarrhythmic medications. Control the heart's rhythm

    Vasodilators. Lessen the heart's work; encourages bloodto flow in a forward direction, rather than backwardsthrough a leaky valve.

    ACE inhibitors. A type of vasodilator used to treat highblood pressure and heart failure

    Beta blockers. Treat high blood pressure and lessen theheart's work by helping the heart beat slower and lessforcefully. Used to decrease palpitations in some patients.

    Anticoagulants ("blood thinners")

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    Surgeries

    heart valve repair orreplacement.

    percutaneous balloon

    valvotomy.

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    Dilated cardiomyopathy

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    Hypertrophic cardiomyopathy

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    Symptoms

    Some people who develop cardiomyopathyhave no signs and symptoms during the earlystages of the disease. Cardiomyopathysymptoms may include:

    Breathlessness with exertion or even at rest Swelling of the legs, ankles and feet

    Bloating of the abdomen due to fluid buildup

    Fatigue

    Irregular heartbeats that feel rapid, pounding orfluttering

    Dizziness, lightheadedness and fainting

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    Causes Long-term high blood

    pressure

    Heart valve problems

    Heart tissue damage from aprevious heart attack

    Chronic rapid heart rate Metabolic disorders

    Nutritional deficiencies ofessential vitamins or

    minerals, such as thiamin(vitamin B-1), selenium,calcium and magnesium

    Pregnancy

    Excessive use of alcoholover many years

    Abuse of cocaine orantidepressantmedications, such as

    tricyclic antidepressants Use of some chemotherapy

    drugs to treat cancer

    Certain viral infections,which may injure the heart

    and trigger cardiomyopathy Iron buildup in your heart

    muscle (hemochromatosis)

    Genetic conditions

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    Types of cardiomyopathy

    1. Dilated cardiomyopathy.

    This is the most common type ofcardiomyopathy

    the pumping ability of your heart's mainpumping chamberthe left ventriclebecomes less forceful; becomes enlarged

    (dilated) and can't effectively pump blood outof the heart

    occurs most often in middle-aged people andis more likely to affect men

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    2. Hypertrophic cardiomyopathy.

    involves abnormal growth or thickening ofyour heart muscle, particularly affecting the

    muscle of your heart's main pumping

    chamber. the heart tends to stiffen and the size of the

    pumping chamber may shrink, interfering with

    your heart's ability to deliver blood to your

    body.

    tends to be more severe during childhood.

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    3. Restrictive cardiomyopathy

    heart muscle becomes rigid and less elastic,meaning the heart can't properly expand and

    fill with blood between heartbeats.

    most often tends to affect older people.

    least common type and can occur for no

    known reason (idiopathic). The condition may

    also be caused by diseases elsewhere in thebody that affect the heart.

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    Complications

    Heart failure.

    Blood clots. Valve problems.

    Cardiac arrest and suddendeath.

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    Tests and Diagnosis

    Chest X-ray

    Echocardiogram.

    Electrocardiogram (ECG).

    Cardiac catheterization and biopsy.

    Cardiac magnetic resonance imaging (MRI).

    Blood tests. One blood test can measure B-type natriuretic peptide (BNP), a protein

    produced in your heart.

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    Treatment

    Dilated cardiomyopathy ACE inhibitors to improve your heart's pumping

    capability, such as enalapril (Vasotec), ramipril

    (Altace) and captopril (Capoten).

    Angiotensin receptor blockers (ARBs) for those

    who can't take ACE inhibitors, such as losartan

    (Cozaar) and valsartan (Diovan).

    Beta blockers to improve heart function, such as

    carvedilol (Coreg) and metoprolol (Lopressor,

    Toprol-XL).

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    Digoxin (Lanoxin). Increases the strength of heart

    muscle contractions; tends to slow the heartbeat. Diuretics. Make you urinate more frequently and

    keep fluid from collecting in your body.

    Commonly prescribed diuretics for heart failure

    include bumetanide (Bumex) and furosemide

    (Lasix). One diuretic, spironolactone (Aldactone),

    may also be helpful in treating scarring of your

    heart tissue. ICD

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    Septal ablation.Also called septalalcohol ablation,this is a treatmentin which a smallportion of the

    thickened heartmuscle isdestroyed byinjecting alcohol

    through a catheterinto the arterysupplying blood toit.

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    Pacemaker implantation ICD

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    Restrictive cardiomyopathy

    Treatment focuses on improvingsymptoms.

    salt and water intake monitoring and

    weight monitoring

    diuretics for sodium and water retention

    medications to lower blood pressure andcontrol fast or irregular heart rhythms.

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    Heart transplant & Ventricular assistive

    devices (VADs)

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    Stress Cardiomyopathy

    Broken heart syndrome

    S/sx: Chest pain

    Shortness of breath

    An irregular heartbeat

    A generalized weakness

    Cx: Death

    Disruptions in your heartbeat

    A fast or slow heartbeat

    Backup of fluid into your lungs (pulmonary edema)

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    Test & diagnosis:

    Personal history and physical exam

    Electrocardiogram (ECG)

    Chest X-ray

    Echocardiogram Blood tests

    Treatment

    angiotensin-converting enzyme (ACE) inhibitors beta blockers

    diuretics

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    What is pericarditis?

    Definition

    The hearts sits in the center of the chest and issurrounded by a sac called the pericardium.

    This sac has two layers, one that fits tightlyonto the heart muscle and another looserlayer surrounding the inner layer.Inflammation of these tissue layers

    surrounding the heart is referred to aspericarditis.

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    What causes pericarditis? Idiopathic

    Mechanical injury to theheart Heart attack and Dressler's

    syndrome

    Heart surgery and postpericardiotomy syndrome

    Infection Bacterial

    Viral Fungal

    HIV

    Tumors or cancer

    Connective Tissue Disease Rheumatoid arthritis

    SLE

    Sarcoidosis

    Metabolic diseases Uremia (kidney failure)

    Hypothyroidism

    Medication Reactions Side effects of phenytoin

    (Dilantin), hydralazine(Apresoline) andprocainamide (Pronestyl,Procan-SR, Procanbid).

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    How is pericarditis diagnosed?

    Physical Evaluation

    Diagnostic Testing

    Electrocardiogram

    Chest x-ray

    Echocardiography

    Blood testing

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    What is the treatment for pericarditis?

    Medicines Nonsteroidal anti-

    inflammatory drugs(ibuprofen)

    Narcotic pain medication

    [codeine, hydrocodone(Vicodin) or oxycodone(OxyContin, Roxicodone)]

    Corticosteroids

    Surgery Pericardiocentesis (a thin

    needle is inserted throughthe chest wall into thepericardial sac)

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    Pericardotomy (cutting a hole inthe pericardial sac)

    Pericardectomy (removing the sac

    completely)

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    Myocarditis

    Definition

    inflammation of heart muscle.

    Causes

    Viruses

    Sarcoidosis

    immune diseases (such as systemic lupus, etc.)

    Pregnancy

    Others

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    Symptoms

    pain in the chest

    weakening of the heart muscle

    heart failure symptoms

    shortness of breath

    Fatigue

    fluid accumulation in the lungs

    Etc

    heart rhythm irregularities from inflammationand/or scarring of the electrical system of theheart.

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    Diagnosis

    Blood tests for heart muscle enzymes(CPK levels) can be elevated

    Electrical testing (EKG) can suggest

    irritation of heart muscle and

    demonstrate irregular beating of the

    heart

    Nuclear heart scan testing can show

    irregular areas of heart muscle.

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    Treatment

    Treatment measures mainly

    involves alleviating heart failure

    (salt restriction, water pills, ACEinhibitors, beta blockers, etc.) and

    treating as well as monitoringheart rhythm abnormalities.

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    Endocarditis

    Definition

    Endocarditis is a serious infection of one of

    the four heart valves.

    Cause

    Endocarditis is caused by a growth of bacteria

    on one of the heart valves, leading to an

    infected mass called a "vegetation".

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    What are the symptoms?

    fever,

    fatigue,

    chills,

    weakness

    aching joints and muscles, night sweats,

    edema in the leg(s), foot (feet), and abdomen,

    malaise,

    shortness of breath, and

    occasionally, scattered small skin lesions.

    anemia, blood in urine, elevated white blood cell

    count, and a new heart murmur.

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    Who is at risk for endocarditis?

    People with existing diseases of

    the heart valves (aortic stenosis,

    mitral stenosis, mitralregurgitation, etc.) and people

    who have undergone heart valvereplacements

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    How is endocarditis diagnosed?

    Transesophageal echocardiography

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    How is endocarditis treated?

    Aggressive antibiotics, generally givenintravenously, usually for 4-6 weeks.

    Amoxicillin

    Ampicillin Erythromycin

    Gentamicin

    Vancomycin

    surgical replacement of the valve

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    HYPERTENSION

    Blood pressure is a measurement of the force againstthe walls of your arteries as your heart pumps bloodthrough your body.

    The top number is called the systolic blood pressure,and the bottom number is called the diastolic bloodpressure.

    High blood pressure (hypertension) is when your bloodpressure is 140/90 mmHg or above most of the time.

    If your blood pressure numbers are 120/80 or higher,but below 140/90, it is called pre-hypertension.

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    Essential HPN

    no cause of high blood

    pressure is found

    Secondary HPN

    Chronic kidney disease

    Disorders of the adrenal gland(pheochromocytoma or Cushingsyndrome)

    Pregnancy

    Medications such as birth control pills,diet pills, some cold medications, andmigraine medications

    Renal artery stenosis

    Hyperparathyroidism

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    Symptoms

    If you have a severe headache, nausea or

    vomiting, bad headache, confusion, changes

    in your vision, or nosebleeds you may have a

    severe and dangerous form of high bloodpressure called malignant hypertension.

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    Diagnosis

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    Complications

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    Treatment

    Lifestyle modification

    Medications

    Diuretics help the body get rid of excess sodium (salt)and water and help control blood pressure

    Beta-blockers reduce the heart rate, the heart'sworkload and the heart's output of blood

    ACE inhibitors help the body produce less angiotensin,which helps the blood vessels relax and open up

    ARBs block the receptors so the angiotensin fails toconstrict the blood vessel

    Calcium channel blockers relax and open up narrowedblood vessels

    Alpha blockers reduce the arteries' resistance relaxing

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    Alpha blockers reduce the arteries resistance, relaxingthe muscle tone of the vascular walls

    Alpha 2 receptor agonist decreases the activity of the

    sympathetic (adrenaline-producing) portion of theinvoluntary nervous system

    Combined alpha and beta-blockers areused as an IV dripfor those patients experiencing a hypertensive crisis

    Central agonists also help decrease the blood vessels'ability to tense up or contract

    Peripheral adrenergic inhibitors reduce blood pressureby blocking neurotransmitters in the brain. This blocksthe smooth muscles from getting the "message" toconstrict.

    Blood vessel dilators, or vasodilators, can cause themuscle in the walls of the blood vessels (especially thearterioles) to relax, allowing the vessel to dilate (widen)

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    ANEURYSM

    Definition

    An aneurysm is an

    abnormal widening

    or ballooning of aportion of an artery

    due to weakness in

    the wall of theblood vessel.

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    Symptoms

    The symptoms depend on the location of theaneurysm. If the aneurysm occurs near thebody's surface, pain and swelling with athrobbing mass is often seen.

    Aneurysms within the body or brain often causeno symptoms.

    If an aneurysm ruptures, pain, low bloodpressure, a rapid heart rate, and lightheadednessmay occur. The risk of death after a rupture ishigh.

    Si d t t

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    Signs and tests

    physical exam.

    CT scan

    Ultrasound

    Treatment

    Surgery endovascular stent repair

    Endovascular embolization.

    E d l t t i

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    Endovascular stent repair

    THROMBOANGITIS OBLITERANS

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    THROMBOANGITIS OBLITERANS

    (BUERGERS DSS.)

    Definition blood vessels of the hands and feet become blocked.

    Cause

    Caused by vasculitis (inflammation of the blood vessels).

    average age when symptoms begin is around 35 years

    history of heavy smoking/chewing tobacco; Raynaud'sdisease.

    very uncommon in children unless if with autoimmune

    diseases.

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    Symptoms Hands or feet may be pale, red, or bluish

    Hands or feet may feel cold Pain in the hands and feet

    Acute, severe

    Burning or tingling

    Often occurring at rest Pain in the legs, ankles, or feet when walking

    (intermittent claudication) Often located in the arch of the foot

    Skin changes or ulcers on hands or feet

    Note: Symptoms may worsen with exposure to cold orwith emotional stress. Usually, two or more limbs areaffected.

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    Signs & Tests

    Angiography/arteriography of

    the extremity

    Doppler ultrasound of the

    extremity

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    Treatment There is no cure for thromboangiitis obliterans. The

    goal of treatment is to control symptoms.

    The patient must stop using tobacco and should avoidcold temperatures and other conditions that reduce

    circulation to the hands and feet.

    Applying warmth and exercising gently may helpincrease circulation.

    Cutting the nerves to the area (surgicalsympathectomy) may help control pain. Aspirin andvasodilators may also used. It may be necessary toamputate the hand or foot if infection or widespread

    tissue death occurs.

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    RAYNAUDS PHENOMENON

    Raynaud's phenomenon (RP) is a condition resulting ina particular series of discolorations of the fingersand/or the toes after exposure to changes intemperature (cold or hot) or emotional events. Skin

    discoloration occurs because an abnormal spasm of theblood vessels causes a diminished blood supply to thelocal tissues.

    White---blue---red

    Affects women between 20-40 When it occurs alone, it is referred to as "Raynaud's

    disease" or primary Raynaud's phenomenon. When itaccompanies other diseases, it is called secondary

    Raynaud's phenomenon.

    h d' h ?

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    What causes Raynaud's phenomenon?

    The causes of primary and secondary RP are unknown.

    What are Raynaud's phenomenon

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    What are Raynaud s phenomenon

    symptoms and signs?

    skin discoloration upon cold exposure

    mild tingling and numbness of the involveddigit(s) that will disappear once the color

    returns to normal. Ulcerated digits can become infected

    Less common areas of the body that can be

    affected by RP include the nose, ears, andtongue. While these areas rarely developulcers, they can be associated with a sensationof numbness and pain.

    How is Raynaud's phenomenon

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    How is Raynaud s phenomenon

    diagnosed?

    Physical exam No single blood test to help the doctor to confirm

    the diagnosis. The doctor can order certain bloodtests (for example, sedimentation rate,

    rheumatoid factor, antinuclear antibody, thyroidhormone levels, and protein levels) to excludeassociated rheumatic diseases and thyroiddisorders.

    Certain maneuvers with the patient's extremitiesto exclude pinched blood vessels that canproduce symptoms that mimic RP, such as inthoracic outlet syndrome.

    What is the treatment for Raynaud's

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    What is the treatment for Raynaud s

    phenomenon?

    Management of Raynaud's phenomenon involves protecting thefingers and the toes from cold, trauma, and infection. Avoiding direct and indirect (passive or secondhand smoke) smoking

    Medications that can aggravate blood vessel spasm should beavoided

    Medications that dilate the blood vessels can be administered.

    Calcium antagonists, such as diltiazem (Cardizem, Dilacor), nicardipine(Cardene), nifedipine (Procardia), and other medicines used in bloodpressure treatment, such as methyldopa (Aldomet) and prazosin(Minipress).

    Low doses of aspirin or dipyridamole (Persantine)

    Some patients with persistent symptoms can benefit by adding amedication called pentoxifylline (Trental), which makes the red bloodcells more pliable and thereby improving circulation.

    Sympathectomy is

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    Sympathectomy issometimes considered.In this procedure, toprevent blood-vesselspasm, the nerves thatstimulate theconstriction of thevessels (sympatheticnerves) are surgicallyinterrupted. the tiny

    nerves around theblood vessels arestripped away.

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    Tests

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    Tests

    Blood Pressure

    Hypertension Tests Blood Pressure

    Monitors

    Heart Tests

    Treatment

    Embolectomy Thrombolysis

    Bypass surgery