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  • Page 1

    KEVIN SPELMAN, PhD, MCPP, CNS

    Contact: [email protected]

    A. Summary of Qualifications

    a. Active Research Scientist

    Previous postdoctoral Fellowship, National Institutes of Health (cannabinoid & cancer research)

    Previous Marie Curie Research Fellow – Paris, France, (anti-plasmodial research)

    Analysis of herb-drug interaction literature (Freeman & Spelman 2008, Mol Nutr Food Res 52:789-98)

    Basic Science Research Experience in Natural Products, UNC, NC (immune & chem research)

    Chemical analysis of cannabinoid products, multiple strains of Cannabis sp.

    Retrospective analysis of cancer patients using Cannabis oil as a therapeutic adjunct

    Past Principle Scientist and director of R&D Lab & Chemical QC at Herb Pharm, Williams, OR

    b. Natural Products Consultant for Government & Leading Companies

    Committee work advising the White House Commission on Comp/Alt Medicine

    Advisor to Jamaican government on natural products industry

    Advisor to James Duke on USDA Ethnobotanical/Phytochemical Database

    Advisor to Oregon Health Authority on Medical Marijuana Program

    Setting up GMP’s for cannabis industry

    Troubleshooting QC processes for major companies – multiple companies

    Regulatory files and Substantiation files – multiple companies

    Producer of scientific animation for MOA’s of select natural products

    c. Writing and Scientific Publishing

    26 scientific peer review publications & 7 book chapters

    5 peer review publications and 3 chapters on PD and PK of complex chemical remedies

    Adverse event reports and toxicology evaluations of botanical products

    Top 20 cited publication in Alt Med Rev

    Editorial Board, Alternative Medicine Studies

    Frequent reviewer for J Pharmaceutical & Biomedical Analysis

    Editorial Advisor – Prevention Magazine

    d. Expertise in Medicinal Plant Research

    Phase I human trials with medicinal plants

    CYP assays – metabolomics applications

    Toxicology probes (cytotoxicity assays)

    Chemical/Metabolomic analysis (MALDI-TOF, HPLC, mass spec, HPTLC)

    Molecular Biology studies (ELISAs, Cell Proliferation, Western Blots, PCR)

    e. Leadership Role in Botanical Medicine and CAM Education

    Cofounder of first MS in clinical herbal medicine

    Producer of on-line education – multiple institutions

    Over 70 CEU/CME lectures at conferences/symposiums

    Founding faculty of first BS in clinical herbal medicine

    Adjunct Assistant Professor of Pharmacy Practice, Mass College of Pharmacy

    Adjunct Assistant Professor, National College of Natural Medicine

    Distinguished Lecturer status, Maryland University of Integrative Health

    f. Clinical Experience in Integrative Medical Practice

    Broad clinical experience with background in scientific rigor

    Practice of Nutritional Counseling, Ayurvedic Medicine & Phytotherapy, 20 years

    Past Chair of Clinical Herbal Medicine Department, Tai Sophia Institute, 5 years

    Multiple years of experience practicing with physicians, 7 years

    g. Foreign Travel and Field Experience

    Clinical and research work in Latin America/Africa/France

    Field medic (urban and mountain settings)

    Delivered CEU lecturers (by invitation) in the UK, Australia and Jamaica

    Medicinal plant harvesting in multiple georegions

    Languages: Spanish – spoken and written; French – beginning

    mailto:[email protected]

  • Page 2

    B. Professional Experience

    2015 Scientific Advisory Board member, Horticultural and Medical Research, advises Oregon Health Authority on Medical Marijuana Program.

    2001-current Consultant, Natural Products & Cannabis Industry. (e.g. AER’s & toxicology evaluations,

    troubleshooting QC, laboratory & regulatory issues, quality control/instrumentation, research potential, substantiation files, etc.)

    2013-current Adjunct Professor, Integrative Sciences Dept. Maryland University of Integrative Health.

    Laurel, MD. Editorial Advisor, Prevention Magazine, New York, NY. 2013 Adjunct Professor, Botanical Medicine Dept., Bastyr University-California, San Diego, CA. 2007-current Consulting Member and Review Board. Appalachian Center of Ethnobotanical Studies

    Medicinal Plant Monographs. Frostburg, MD. Adjunct Professor, Botanical Medicine Dept. National College of Natural Medicine.

    Portland, OR. Distinguished Lecturer. Herbal Medicine Dept., Maryland University of Integrative Health,

    Laurel, MD. 2008-2011 Massachusetts College of Pharmacy and Health Sciences The Phytochemistry of Medicinal Plants – Training Course for Pharmacists 2011-2013 Principle Scientist and Director of Research and Development Laboratory, Herb Pharm,

    Williams, OR. 2011-2009 Co-advisory to McCormick & Company, Inc. on the use of spices for consumer wellness and product development. 2010 Expert testimony to Maryland House of Delegates and Maryland Senate on safety issues

    concerning botanical medicines and supplements. 2010-current Editorial Board. Alternative Medicine Studies 2008-current Adjunct Assistant Professor of Pharmacy Practice, School of Pharmacy—Boston, Massachusetts College of Pharmacy and Health Sciences, Boston, MA. 2007 Adjunct Researcher. Bastyr University. Kenmore, WA. 2007-2008 Special Volunteer Appointment. National Institute on Aging. 2006 Director of Certification, American Herbalist’s Guild. Study of the implementation of a

    national certification exam for clinicians using botanical medicine.

    Advisor for Product Research & Development of the Scientific Research Council, an agency of the Ministry of Commerce, Science & Technology of Jamaica.

    2005-2008 Adjunct Research Scientist. Chem/Biochemistry Dept.University of North Carolina,

    Greensboro.

    2004-06 Re-elected, Council/Board of Directors. American Herbalists Guild, WatervilleVlly, NH. Herbal Standards and Practices Committee, Appointed Member. Tai Sophia Institute, Laurel, MD.

  • Page 3

    2003-07 Appointment as Chair-Clinical Division, Herbal Medicine Department, Tai Sophia

    Institute, Laurel, MD. 2002-2007 Clinical Chair/Clinical Supervisor for MS in Clinical Herbal Medicine. Tai Sophia Institute 2002-2005 Nutritional Counseling. Tai Sophia Center of Healing Arts. Laurel, MD. 2002-2004 Herbal Legal Task Force. Study of legal aspects of the practice of herbal medicine. Tai Sophia Institute, Laurel, MD.

    2002 Elected to Council/Board of Directors. American Herbalists Guild. Canton, GA.

    Appointed Exam Committee & Board Member. Botanical Medicine Academy. Vashon, WA.

    2001-2011 Appointment as core faculty, Academic courses held: Physiology, Pathophysiology,

    Pharmacology, Clinical Assessments. Tai Sophia Institute, Laurel, MD. 2001 Committee member. National Policy Dialogue on CAM. Washington, DC. Nutritional Counseling. Group Practice. Traditional Acupuncture Clinic. Columbia, MD. National Center on Complementary and Alternative Medicine Colloquium. Wash, DC. 2000-2005 Adjunct Assistant Instructor. Research Dept.; Botanical Medicine Dept. Ayurvedic

    Medicine/Botanical Medicine. Southwest College of Naturopathic Medicine, Tempe, AZ. 1999-2008 Editorial Board. Journal of the American Herbalists Guild. 1999-2001 Board member. National College of Phytotherapy, Albuquerque, NM. 1999-2001 Group Family Practice. Aaron Kaufmann, DO. Clinic for Health and Wellness,

    Albuquerque, NM.

    Nutritional Counseling. Clinic of Collaborative Medicine. Albuquerque, NM. Faculty. Life Sciences, Energetic Medicine, Botanical Medicine. National College of

    Phytotherapy, Albuquerque, NM. 1999 Nutritional Counseling. Healthcare Provider. St. Joseph’s Hospital Healthcare System.

    This was an innovative program to create access to CAM therapies via a PPO.

    1989-1999 Private Practice. Family Practice. Albuquerque, NM. Health Care Consultant. Centro de Atención Infantil Piña Palmera. Zipolite, Mexico. 1997 Teaching Assistant. Microbiology, University of New Mexico, Albuquerque, NM. 1996-99 Natural Products Industry Consultant. Natural Products Expo West, Anaheim, CA & Expo East, Baltimore, MD. 1995-1996 Nutritional Counseling. Family Practice. Puerto Angel, Oaxaca, Mexico. 1994-2001 Faculty. Botanical Medicine. Ayurvedic Institute, Albuquerque, NM. 1990-1992 Herbal Pharmacist for Dr. Vasant Lad. Ayurvedic Wellness Center, Albuquerque, NM.

  • Page 4

    Publications, Peer review (*corresponding author)

    2014 N.Singh

    N, Ravichandran S, Spelman K, Fugmann SD, Moaddel R. The identification

    of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with

    protein coated magnetic beads. J Chromatogr B. Mar 15. pii: S1570-0232(14)00187-1. doi: 10.1016/j.jchromb.2014.03.016. [Epub ahead of print]

    2013 Asher G, Spelman K. Clinical Utility of Curcumin Extract. Alt Ther Health Med 19(2):14-6. Lyles J, Tyler P, Spelman K, Pierce ST, Brown C, Quave C. Comparative Phytochemical Analysis of Chinese and American Starvine by HPTLC and HPLC. Conference Poster. Society of Ethnobiology.

    2012 *Spelman K. Cannabinoid-Opioid Interaction in Chronic Pain. Nat Med J June 2012. Muñoz Durango K…Spelman K….Figadere B. Detection, characterization and screening of heme binding molecules by mass spectrometry for malaria drug discovery. Anal Chem

    84(7):3324-9. *Spelman K. The Pharmacodynamics, Pharmacokinetics and Clinical Use of Echinacea purpurea. America’s Pharmacist October. Borchard J. Mazzarella L. *Spelman K. A review of medicinal plants that modulate nitric oxide activity. Alt Med Studies .2012; 2:e6 doi:10.4081/ams.2012.e6.

    2011 Spelman K, et al. The Antiplasmodial effects of a traditional Paraguayan remedy: Zanthoxylum chiloperone against chloroquine resistant and mefloquine resistant strains of

    Plasmodium falciparum. Brazilian J Pharmacog 21(4):652-61. *Spelman K, et al. The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo anti-malarial activity. Phytother Res 25(7):1098-1101. Moaddel R, Rosenberg A, Spelman K…Wainer IW. Development and Characterization of Immobilized Cannabinoid Receptor (CB1/CB2) Open Tubular Column for On-line Screening. Anal Biochem 412(1):85-91. *Spelman K, et al. Traditional herbal remedies that influence cell adhesion molecule activity. Phytother Res 25(4):473-83.

    2010 Burns JJ,…*Spelman K. The influence of traditional herbal formulas on cytokine activity.Toxicology 278(1):140-159.

    2009 Spelman K, Iiams-Hauser K, Cech NB, Taylor EW, Smirnoff N, Wenner CA. Role for

    PPARγ in IL-2 inhibition in T cells by Echinacea derived undeca-2E-ene-8,10-diynoic acid isobutylamide. Int Immunopharmacol 9(11):1260-4.

    Clare B, Conroy C, *Spelman K. The diuretic effect in Human Subjects of an ethanolic

    extract of Taraxacum officinale folium over a single day. J Alt Comp Med 15(8):929-34.

    Spelman K, et al. Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS.J Pharm Biomed Anal 49(5);1141-9. *Spelman K. “Silver Bullet” Drugs vs. Traditional Herbal Remedies: Perspectives on Malaria. HerbalGram J Am Bot Council 84:44-55.

  • Page 5

    Spelman K. The extraction, stability, metabolism and bioactivity of the alkylamides in Echinacea spp. Thesis, successfully completed for School of Biosciences, University of Exeter.

    2008 Freeman, C & *Spelman, K. A Critical Evaluation of Drug Interactions with Echinacea spp. Mol Nutr Food Res 2008; 52:789-98. *Spelman K. Echinacea purpurea radix and Taraxacum officinale radix ethanolic extracts ameliorate acute allergic reactions in two patients. J Am Herb Guild 7(2).

    2007 *Spelman K, Yesko J. Paradise Nearly Lost: Jamaica Forgotten. HerbalGram, J Am Bot

    Council. 74:44-53. *Spelman K. Chronic Fatigue Syndrome: A Look at Physiological Processes and Therapies. J Am Herb Guild 7(1):39-48.

    2006 Cech N, Tutor K, Hovater BA. Spelman K. et al. Liver enzyme-mediated oxidation of

    Echinacea purpurea alkylamides: Production of novel metabolites and changes in immunomodulatory activity. Planta Medica 72(14):1372-77. Hovater BA, Smith D, Spelman K, et al. LC/ESI-MSn for the determination of bioactive liver metabolites of Echinacea purpurea. Abstracts of Papers of The American Chemical Society 231:101. *Spelman K, Burns JJ, Nichols D et al. Modulation of Cytokine Expression by Traditional

    Medicines: A Review of Herbal Immunomodulators Alt Med Rev 11(2):128-50. 2005 *Spelman K. Philosophy in Phytopharmacology: Ockham’s Razor vs. Synergy. J Herb

    Pharmacol 5(2):31-47.

    2004 *Spelman K. Allostasis: stability through change. Aust J Med Herb 16(4):99-109.

    2002 Committee Paper. National policy dialogue to advance integrated health care:

    Finding common ground-Final report to the Whitehouse. Alt Ther Health Med 8(3):S2-S16.

    2000 VanderJagt DJ, Spelman K, et al. Folate and B12 Status of Adolescent Girls in Northern Nigerian. J Natl Med Assoc 92(7):334-40.

    C. Book Chapters and Contributing Excerpts (by invitation)

    . 2011 Snow J & Spelman K. Medicinal plants and spices influence on the digestive process. In

    ADA Pocket Guide to Gastrointestinal Nutrition. 3rd

    ed. ADA. Publication in process.

    Snow J & Spelman K. The influence of bitter, aromatic and pungent medicinal plants on gut function. In The Gastrointestinal & Liver Disease Nutrition Desk Reference, CRC.

    2010 Spelman K. Ecological Pharmacology: Pharmacology Informed by Evolution. In Fundamentals of Complementary and Integrative Medicine, 4ed. Elsevier.

    2009 Kirakosyan A, Kaufmann P, Boik J, Spelman K, Seymour M. Types of Interactions of Plant

    Metabolites –Synergistic Modes of Interactions. In Recent Advances in Plant Biotechnology, I.k.international.

    2007 Spelman K. Clinical Case Study on Adaptogens in: Winston D. Adaptogens: Herbs for Strength, Stamina and Stress Relief. Healing Arts Press.

  • Page 6

    2006 Spelman K, Duke J, Bogenschutz-Godwin M. The Synergy Principle with Plants,

    Pathogens, Insects, Herbivores and Humans. Chapter in: Natural Products from Plants. CRC Press.

    2004 Spelman K. Herb Drug Interactions. Pharmacokinetic/Pharmacodynamics. In Emergency Care of the Geriatric Patient. Jones & Bartlett.

    1998 Spelman K, Excerpt on Nettles and Ayurvedic Medicine: in Schofield, J. Nettles. Keates

    Publishing Inc. 1998.

    D. College Lectures and CME/CEU Lectures

    2015 National Ayurvedic Medical Association

    Plenary Session - Science Meets Ayurveda: The Beauty of a Bimodal Understanding Panel Discussion – The Future of Ayurvedic Medicine American Academy of Anti-Aging Medicine Botanical Medicines in Infectious Diseases – 16 hr CME course co-taught with Dr. Christopher Hobbs

    Functional Medicine University A Model for Understanding the Need for Phytochemistry in Human Health Ecological Pharmacology – A Co-Evolutionary Dependence for Plants & Humans The Pharmacology of Medicinal Plants – A Glimpse at Network Pharmacology Herb Drug Interactions – Perspectives and Data Cannabis 101 – An Intro to Chemistry, Pharmacology, Safety and Therapeutics Medical Cannabis Conference The Endocannabinoid System Beyond THC: The Chemistry of Cannabis

    2014 American Academy of Anti-Aging Medicine Introduction to Botanical Medicine – 16 hr CME course Naturopathic Medical Students Association Conference The Need for Phytochemistry in Human Health Integrative Research Panel American Advancement of Restorative Medicine 2 CME lectures on Botanical Medicine

    2013-current National College of Naturopathic Medicine. Living Herbal Medicine: Grow, Harvest, Formulate & Prescribe Intensive. 1 week intensive (3 cr). Co-taught with Glen Nagle, ND.

    2013 American Herbalists Guild Symposium

    Keynote Presentation: Where We Are and Where We Are Going Medicinal Plants for Malaria: A Realistic Use of herbals? Echinacea Update: What’s New

    Breitenbush Herbal Conference.

  • Page 7

    The Endocannabinoid System: CB Activating Plant Molecules from Cannabis sp. and Other Medicinal Plants. Echinacea Update The Use of Pulse and Tongue in Clinical Work

    2012 American Herbalists Association Conference (formerly AHG). The Molecular Biology of Immunomodulators Xenohormesis: Plants Signaling Humans Ecological Pharmacology

    American Association of Naturopathic Physicians. The Endocannabinoid System: CB Activating Plants molecules beyond Cannabis spp. Bellevue, WA.

    National College of Natural Medicine. Living Herbal Medicine: Grow, Harvest, Formulate and Prescribe Intensive. 1 Week intensive (3 credits). Co-taught with Glen Nagle, ND.

    2010 Georgetown University, Masters in Complementary Alternative Medicine;

    Traditional Perspectives vs Scientific Understanding of Medicinal Plants. Washington, D.C. Johns Hopkins Bloomberg School of Health. Nutrition Seminar. Department of Human Nutrition. Ecological Pharmacology. Baltimore, MD. American Herbalists Guild Conference. Austin, TX. Science in Herbalism: What do we really need to know (and how to learn it). Ayurvedic Diagnosis for the Western Herbalist.

    2008-07 University of North Carolina. Chemical Ecology. Greensboro, NC. Lecture in Environmental Chemistry Course.

    2007 Canadian Society of Pharmaceutical Sciences/Pharmaceutical & Biomedical Analysis

    Conference. Ecological Pharmacology: The case for multicomponent remedies. International Complementary & Natural Healthcare Expo, NYC; Education and Research in the field of CAM.

    American Herbalists Guild Conference (AHG) Columbia, MD; Echinacea purpurea radix and Taraxacum officinale radix ethanolic extracts ameliorate acute allergic reactions in two patients.

    2006 Maine General Hospital: Herbal remedies: An addition to the Healthcare providers tool box… 2005 College of Practitioners of Phytotherapy Seminar Series, Phytotherapy & Alzheimer’s

    Disease, London, England; Neurodegenaration, stress and inflammation. Building Neurological Reserve. American Herbalists Guild Conference (AHG), Portland, OR; Pulse Diagnosis Intensive. AWARE Conference. Keynote Address: Coherent Coupling with a Conscious Planet: An Element of Healing. Phoenix, AZ.

    Southwest School of Botanical Medicine. Bisbee, AZ; A Relationship, Humans & Plants.

    2004 Co-Presenter with J. Cott; P. Gardiner; M. McGuffin; A. Romm. American Public Health

    Association, Washington, DC;

  • Page 8

    Modern Perspectives on Botanical Medicine. American Herbalists Guild Conference, (AHG) NH;

    Cytokines and Botanical Immunomodulators Chronic Fatigue Syndrome: Physiological Processes and Therapeutics National Herbalists Association of Australia, Canberra, Australia; Allostasis: Suffering the Slings and Arrows of Outrageous Fortune. Botanical Modulation of Cytokines. Panel, The Future of Herbal Medicine. 2003-2005 Johns Hopkins Bloomberg School of Health Complementary, Alternative, Integrative and Indigenous Medicines. Botanical Medicines. Baltimore, MD. 2003 AHG Conference, NM; Reading the Tongue, Reading the Constitution, Intensive. Beyond Selye, Homeostasis Revisited. Mid-Atlantic College Health Association Annual Meeting, Hunt Vlly, MD; Safety & Efficacy of Herbal Medicines

    2002 AHG Conference, WI;

    Rethinking Western Physiology: Cell to Cell Communication. Clinical Practicum. Fundamentals of Ayurvedic Medicine, Intensive.

    Bastyr University. Seattle, WA; Intensive Course: Intro to Herbal Medicine.

    2001 AHG annual conference. Atlanta, GA;

    The GI tract as the Beginning of Disease. The Stress Axis.

    Frontier Herbfest. Norwary, Iowa;

    Fractal Physiology. Ayurveda, A constitutional approach. The Stress Axis as a Physiological and Psychological Crossroads in Health and Dis-ease.

    Bastyr University. Seattle, Washington; Advanced Materia Medica.

    National College of Naturopathic Medicine. Portland, OR; Advanced Materia Medica.

    Las Vegas Medical Center, LV, NV; Hepatitis C, Do Botanical Medicines Offer Benefit?

    Southwest College of Naturopathic Medicine. Tempe, AZ; Advanced Therapeutics. 20 hr course. SWCNM. Tempe, AZ; History of Botanical Medicine. 20 hr course.

    2000 SWCNM. Tempe, AZ. Ayurvedic Botanical Prescription. 20 hr course.

    NCNM. Portland, OR; Introduction to Ayurvedic Medicine. 20 hr course.

    University of NM, Pharmacology 543, Albuquerque, NM; Botanical Medicine.

    Southwest Conference of Botanical Medicine, Tempe, AZ;

  • Page 9

    Immunomodulators as Adjuvants in the Treatment of Cancer. Botanical Modulation of the Hypothalamus-Pituitary-Adrenal Axis. Withania somnifera, Immunomodulator and Adaptogen.

    Albuquerque Dietics Association. St. Joseph’s Hospital, Albuquerque, NM; An Ayurvedic Approach to Nutrition National College of Naturopathic Medicine, Portland, OR; Materia Medica, Immune System.

    Case Studies in the Treatment of Depression. Grand Rounds. Ayurvedic Medicine, An Introductory Seminar. Immune System Botanicals. Botanical Medicine.

    Immunomodulators in the Treatment of Cancer. Advanced Botanical Medicine.

    1999-2000 Albuquerque Oncology Nursing Society. Alb, NM; Botanical Medicines in Cancer.

    1997 Materia Medica, National College of Naturopathic Medicine, Portland, OR; Cardiovascular System

    American College of Integrative Medicines, Albuquerque, NM; Clinical Applications of Botanical Medicines. AHG Conference, Pocono, PA; GABAergic Modulation of Hypericum spp. A Rationalists Approach to Energetic Medicine. Albuquerque Oncology Nursing Association, NM. The Role of Plant Medicines in the Treatment of Cancer.

    1998 University of New Mexico Hospital Cancer Center, Albuq. NM. Botanical Agents in the Treatment of Cancer.

    1997 Lovelace Medical Center, Albuquerque, NM; St. John’s Wort: Herb of the Sun. Echinacea: Myth or Medicine. Alternatives for Menopause.

    1995-97 Intensive courses for nurses. New Mexico Center for Nursing Therapeutics, Albuquerque, NM;

    Nursing Herbs. Herbal Interventions for Healthcare Professionals. 1997-99 Intensive course for nurses. Ft. Bayard Medical Center, Ft. Bayard, NM: Herbal Interventions for Healthcare Professionals. Ayurveda for Healthcare Professionals. 1994 St. Joseph’s Hospital, Albuquerque, NM. Conference in Alternative Therapies. 1992-95 Guest lecturers at various organizations and institutions including;

    St. Joseph Healthcare Foundation and Hospital, Albuquerque, NM. Presbyterian Hospital, Albuquerque, NM. University of New Mexico Medical School, Albuquerque, NM.

    New Mexico Department of Public Health. 4th Annual Alaskan Herbal Conference. Wasilla, AK.

    College of Nursing, University of New Mexico, Albuquerque, NM. St. John’s College, Santa Fe, NM.

  • Page 10

    F. Ongoing Research Support

    Spelman, Kevin (PI) 7/08 – current Maryland University of Integrative Health Phytochemical activation of PPAR isotypes. Literature review of the phytochemicals that affect PPAR activity. Spelman, Kevin (PI) 9/12 - current Emory University & Herb Pharm Research and Development Laboratory Phytochemical Comparison of Schisandra chinensis to S. glabra Spelman, Kevin (PI) 8/11 - current Herb Pharm Research and Development Laboratory Phytochemical Comparison of Verbascum thapsus to V. speciosum Spelman, Kevin (PI) 9/11 - current Herb Pharm R&D Lab Phytochemical Comparison of Ligusticum porteri to L.grayii Spelman, Kevin (PI) 8/12 - current Herb Pharm R&D Lab Phytochemical Comparison of Actaea racemosa to A.elata and A. rubra

    G. Completed Research Support

    Moaddel, Ruin (PI) 7/11 – 5/13 National Institute on Aging & Herb Pharm R&D Lab

    Role of Trigonella foenum-graecum extract on SIRT6 Moaddel, Ruin (PI) 09/11 – 01/13 National Institute on Aging Ligand fishing from a complex phytochemical matrix to detect ligands of SIRT6 Role: Research Scientist

    Wainer, Irving (PI) 12/09 – 1/11 National Institute on Aging Role of nuclear orphan receptors in brain cancer. Role: Research scientist Grellier, Philippe (PI) 04/09 – 10/11 Muséum national d'Histoire naturelle, Paris In vitro antiplasmodial effects of Zanthoxylum chiloperone extracts and isolated alkaloids. Role: Primary research scientist Grellier, Philippe (PI) 04/09 – 7/09 Muséum national d'Histoire naturelle, Paris In vivo and in vitro antiplasmodial effects of Spilanthes acmella extracts and isolated alkylamides. Role: Primary research scientist Figadère, Bruno (PI) 01/09 – 07/09 Laboratoire de Pharmacognosie et Groupe Chimiothérapie Antiparasitaire, U Paris Detection of antimalarial heme binding small molecules by mass spec. Role: Research scientist Figadère, Bruno (PI) 01/09 – 04/09

  • Page 11

    Laboratoire de Pharmacognosie et Groupe Chimiothérapie Antiparasitaire, U Paris Extractions of Lannea velutina against trypanosomes and cancer cell lines. Role: Research scientist Wenner, Cynthia (PI) 0407 – 12/08 Seed Grant, Bastyr University Effects of Echinacea purpurea extract and alkamides on PPARγ. This study examines a novel hypothesis on the mode of activity of E. purpurea radix. Role: Primary research scientist Cech, Nadja (PI) 09/06 – 0908 University of North Carolina Comparison of alkylamide yield in fresh versus dry ethanolic extracts of Echinacea purpurea utilizing HPLC-ESI-MS. An investigation comparing different types of ethanolic extracts of E. purpurea. Role: Primary research scientist Spelman, Kevin (PI) 06/01/05 Tai Sophia Institute Parasympathetic and sympathetic effects of Lobelia inflata extract on human subjects. A pilot trial investigating the effects of L. inflata.. Role: PI Spelman, Kevin (PI) 08/05-10/06 Tai Sophia Institute Diuretic Effects of Taraxacum officinale hydroethanolic extract on healthy human subjects. This pilot study monitored the diuresis of subjects ingesting a hydroethanolic extract of Taraxacum

    officinale. Glew, Robert (PI) 06/00 – 08/00 MIRT, U New Mexico Bone markers in Nigerian men. This study, conducted in Africa, examined bone parameters and screened for hypertension. Role: Research scientist Glew, Robert (PI) 06/00 – 08/00 MIRT, U New Mexico DHA and LA levels in Kanuri tribal women’s breast milk. This study, conducted in Africa, examined the fatty acid content of breast milk in an unstudied population. Role: Research scientist Glew, Robert (PI) 06/00 – 08/00 MIRT, U New Mexico Folate levels in Nigerian early teenage girls. This study, conducted in Africa, investigated serum folate levels of teenage girls. Role: Research scientist

    H. Education

    Fellowships

    2011-2009 Postdoctoral Fellowship. Bioanalytical Chemistry and Drug Discovery Section. Laboratory of Clinical Investigation. National Institute on Aging, NIH.

    2009 Marie Curie Fellowship: European Early Stage Training. Biologie fonctionnelle des

    protozoaires, Développement et Diversité Moléculaire Muséum national d'Histoire naturelle, Paris.

  • Page 12

    Graduate Studies 2010-11 Bioethics Program, National Institutes of Health, Bethesda, MD. 2009 PhD, Molecular Biology. Cross disciplinary research, Chemistry/Biology.

    University of Exeter. Devon, England and University of North Carolina, Greensboro.

    Undergraduate Studies

    1998 Bachelors, Biochemistry, Cum Laude. University of New Mexico, Albuquerque, NM. 1989-91 Basic, Intermediate and Advanced Emergency Med Tech training and licensure.

    Complementary Alternative Medicine

    1992-93 Study of clinical herbal medicine, Clinical Practicum. New Mexico Herb Institute. Alb, NM.

    1992 Study of clinical herbal medicine. Southwest School of Botanical Medicine, Alb, NM.

    1992-1994 Clinical Training in Indigent Health Care. New Mexico Herb Institute. Albuquerque, NM. 1988 Residency in clinical Ayurvedic medicine. Clinical practicum. Ayurvedic Institute,

    Albuquerque, NM. 1987-88 Ayurvedic Medicine; Lifestyle Counseling. Ayurvedic Institute.

    I. Professional Affiliations

    American College of Physicians Society of Integrative Medicine American College of Nutrition American Herbalist Guild

    American Society of Internal Medicine American Society of Pharmacognosy Ayurvedic Institute Phi Theta Kappa Honor Society Golden Key National Honor Society United Plant Savers

    J. Awards

    2014 Great Esteem Award (providing excellence in didactics 2012- 2014) Maryland University of Integrative Health, Laurel, MD.

    2010 Great Esteem Award (providing excellence in educational training 2008- 10) Tai Sophia Institute, Laurel, MD.

    1999 People’s Caring Award. Recognition of Distinguised Service. People Living Through Cancer. Albuquerque, NM.

    K. Certificates and Licensures

    Advanced Cardiac Life Support Pediatric Advanced Life Support Certified Nutrition Specialist Member College of Practitioners of Phytotherapy Registered Herbalist, American Herbalists Guild Lifestyle Counseling, Ayurveda

  • Page 13

    L. Interests/Hobbies

    Slacklining Skiing; competitive racer, past licensed racing coach, past ski patrol, past certified instructor

    Cycling; past racer, unicycle rider Musician – piano & trumpet

    Travel and Foreign Cultures, lived in Latin America; Paris, France; Nigeria; visited 13 countries

    References available on request