ih&s 725 dr. myers, c.i.h. occupational air sampling strategies – who, when, how…. lecture...

IH&S 725 Dr. Myers, C.I.H.

Occupational Air Sampling Strategies – who, when, how….

Lecture Notes

IH&S 725 Dr. Myers C.I.H.

Components of a Sampling Strategy

Characterization and information gathering Risk assessment and sampling priorities Air sampling strategy and analysis Data interpretation Recommendation and reporting Re-evaluation


Air sampling strategy

Which employee or employees should be sampled?

How many samples should be taken on each workday sampled to define the employee’s exposure?

How long should the sampling interval be for a measurement sample?


Air sampling strategy

What periods during the workday should the employee’s exposure be sampled?

How many workdays during the year should be sampled and when?

Time to result – acute vs. chronic and direct reading real time vs. sampling media and two-week lab time.



OSHA regulation requires the sampling of the “employee believed to have the greatest exposure” or the “maximum risk employee” - principle extended to include groups of employees

Use the exposure risk/health risk priority matrix



If the maximum risk employee or group can’t be identified then do random sampling of the group of workers.

Objective is to select a subgroup of adequate size so that there is a high probability that the random sample will contain at least one worker with high exposure if one exists. Want to be careful about use of group statistics


NIOSH’s Occupational Exposure Sampling Strategies Manual

Gives one sample size model Set up to ensure with

90% confidence that at least one person from the highest 10% exposure group is contained in the sample

Conversely 10% chance of missing someone in the highest 10% exposure group


Samplingperiods

Various types of sampling periods possible

As you increase the # of sample periods in a shift the analysis becomes more sophisticated


How many workdays during the year should be sampled and when?

OSHA regulation can differ Substance specific standards specify sample

interval dependent on the exposure level relative to the PEL


1910.1025 Lead

1910.1025(c)(1) The employer shall assure that no employee is exposed to lead at concentrations greater than fifty micrograms per cubic meter of air (50 ug/m(3)) averaged over an 8-hour period.

1910.1025(c)(2) If an employee is exposed to lead for more than 8 hours in any work day, the permissible exposure limit, as a time weighted average (TWA) for that day, shall be reduced according to the following formula: Maximum permissible limit (in ug/m(3))=400 divided by hours

worked in the day.


1910.1025 Lead

1910.1025 (d) Exposure monitoring - 1910.1025(d)(1)(ii) With the exception of monitoring

under paragraph (d)(3), the employer shall collect full shift (for at least 7 continuous hours) personal samples including at least one sample for each shift for each job classification in each work area.

1910.1025(d)(1)(iii) Full shift personal samples shall be representative of the monitored employee's regular, daily exposure to lead.


1910.1025 Lead

1910.1025(d)(2) Initial determination. Each employer who has a workplace or work operation covered by this standard shall determine if any employee may be exposed to lead at or above the action level.

1910.1025(d)(4)(i) Where a determination conducted under paragraphs (d)(2) and (3) of this section shows the possibility of any employee exposure at or above the action level, the employer shall conduct monitoring which is representative of the exposure for each employee in the workplace who is exposed to lead.


1910.1025 Lead

1910.1025(d)(6) Frequency. 1910.1025(d)(6)(i) If the initial monitoring reveals employee

exposure to be below the action level the measurements need not be repeated except as otherwise provided in paragraph (d)(7) of this section.

1910.1025(d)(6)(ii) If the initial determination or subsequent monitoring reveals employee exposure to be at or above the action level but below the permissible exposure limit the employer shall repeat monitoring in accordance with this paragraph at least every 6 months. The employer shall continue monitoring at the required frequency until at least two consecutive measurements, taken at least 7 days apart, are below the action level at which time the employer may discontinue monitoring for that employee except as otherwise provided in paragraph (d)(7) of this section.


1910.1025 Lead

1910.1025(d)(6)(iii) If the initial monitoring reveals that employee exposure is above the permissible exposure limit the employer shall repeat monitoring quarterly. The employer shall continue monitoring at the required frequency until at least two consecutive measurements, taken at least 7 days apart, are below the PEL but at or above the action level at which time the employer shall repeat monitoring for that employee at the frequency specified in paragraph (d)(6)(ii), except as otherwise provided in paragraph (d)(7) of this section.

1910.1025(d)(7) Additional monitoring. Whenever there has been a production, process, control or personnel change which may result in new or additional exposure to lead, or whenever the employer has any other reason to suspect a change which may result in new or additional exposures to lead, additional monitoring in accordance with this paragraph shall be conducted.


Limited basic statistics review

What is a population?

What is a sample?


Population and sample means

N

N

1iix

Population

n

x

n

1iix

Sample


Population variance and standard deviation

2

1

2

2

deviation Standard

Varience

Population

N

xN

ii


Sample variance and standard deviation

2

1

2

2

s deviation Standard

1 Varience

Sample

s

n

xxs

n

ii


Point estimate

A point estimate of some population parameter is a single numerical value of a statistic


2-sided confidence interval on the mean

Two sided CI P(L ≤ µ ≤ U) = 1-α where 0 ≤ α ≤ 1

n

stx

n 1,21-1CL


Confidence Interval on sample mean:

n

stx n 1,1-1CL

interval confidence sided-One

α is assigned to either the upper or lower tail of the t-distribution


Where does t come from

Definition Let X1 X2 ….Xn be a random sample for a normal

distribution with unknown mean and unknown variance σ2. The quantity

has a t-distribution with n-1 degrees of freedom.

nSX

T


t-distribution and α

Probability density function i.e.. area under the curve = 1.

α represents the area assigned to the tail(s) of the distribution – probability of T > t1-α &/or -tα

Note that t1-α = -tα


Example #1

Using the t-table determine the t-value with 14 df that leaves an area of 0.025 to the left (and therefore an area of 0.975 to the right).

145.2975.0

025.0975.01

t

tttt


Example #2

What is the P(-t0.025 < T < t0.025)?

Since t0.025 leaves an area of 0.025 to the right and -t0.025 leaves and area of 0.025 to the left the total area (probability) between -t0.025 and t0.025 is?


Influence of degrees of freedom on the t-distribution

The area to the left or right of tα and t1-α decreases with increasing df


Standard normal distribution, SND

Definition If is the mean of a random sample of size n taken

from a population with mean µ and variance σ2, then the limiting form of the distribution of

as n ∞, is the standard normal distribution snd(z;0,1).

n

XZ


Using the standard normal distribution

Using the z-table, find the area under the curve that lies: to the right of z = 1.84

between z = -1.97 and z = 0.86


Example #3

Given a normal distribution with µ = .05mg/m3 and σ = 0.01, find the probability that a sample point estimate of µ would fall between 0.04 and 0.06mg/m3.


Example #3 solution

First calculate the z-value corresponding to x1 = .04mg/m3 and x2 = .06mg/m3


Example #3 solution con’t

Second determine the probability P(0.04mg/m3 < x < 0.06mg/m3) = P(-1< z < 1)

68.3%or 6826.

1587.8413.

)1()1()11(

P

P

zPzPzP

ih&s 725 dr. myers, c.i.h. occupational air sampling strategies – who, when, how…. lecture...

Documents

exposure group slide

employees exposure

sampling interval

random sampling

sampling media

high exposure

greatest exposure

pel slide