genetics graduate group handbook - 2007

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Page 1: Genetics Graduate Group Handbook - 2007
Page 2: Genetics Graduate Group Handbook - 2007

1

Table of Contents

Genetics Graduate Group Advising Highlights

Course list

Seminar List

Expanded Guidelines for Qualifying Exam

Focus Groups

Animal Genomics

Chromosome Biology

Human Genetics

Model Plants

General Genetics

Plant Breeding and Biodiversity

Requirement Spreadsheet

Executive Committees

Advisor List

Faculty Roster

Student Roster

Forms

Page 3: Genetics Graduate Group Handbook - 2007

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Genetics Graduate Group Advising Highlights

New Student Orientation- Fall 2007

You have two official faculty mentors recognized by the Office of Graduate Studies:

1. Academic Adviser

2. Major Professor (also known as your Dissertation Adviser or Thesis Adviser)

Academic advisers are nominated by the Genetics Graduate Group and appointed by Graduate Studies.

You will initially be assigned an adviser based on research interests and your application. You may

change your adviser after consultation with the Master Adviser.

The Master Adviser is a faculty member whose job is to coordinate the group’s advising activities. The

Master Adviser, as well as advisers not assigned specifically to you, can advise you if your academic

adviser is not available (for example, out of town).

Meet with your academic adviser to:

Plan coursework

Ensure that deficiencies are dealt with and that remedial courses are taken

Ensue that required coursework is taken

Monitor your progress in finding your research home

Get help in dealing with university bureaucracy

Get assistance if you encounter problems with GGG program or major professor

Approve/sign petitions for late drop/PELP/Advancement to Candidacy

Get career advice

Receive periodic review of your progress

Others can serve as mentors as well. The Graduate Group Coordinator, Ellen Picht, is also a resource

(Graduate Group Complex, 310 Life Sciences).

Important notes:

1. If you are a full-time student you must enroll in 12 units every quarter. If you are taking

classes, you can register for 299 units to bring you up to 12 units. Once you stop taking classes,

enroll in 12 units of GGG 299 with your major professor. Don’t let your registration lapse (you do

not have to register for the Summer). You must either be registered or on filing fee the quarter you

submit your thesis/dissertation.

2. You must receive a B or better in the required GGG courses and maintain an overall B average.

3. With the approval of your Academic Adviser, you may petition to take one graded upper division or

graduate course per academic term on an S/U basis.

Page 4: Genetics Graduate Group Handbook - 2007

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Meeting with your Academic Adviser.

You are responsible for organizing and arranging these regular meetings. If you are having problems at

any time, see your Academic Adviser right away.

First Quarter Guiding Committee Meeting-

Meet with your Guiding Committee sometime during the first quarter (two other members are

assigned). If you are a member of a lab already, your future major professor should also be a member.

Identify any prerequisites/deficiencies that need to be taken.

Discuss Winter/Spring course possibilities- discuss electives

Discuss research interest/rotations

Discuss focus group interest-decide if should switch advisers, guiding membership

Form must be submitted to GGG by you after meeting is held and signatures obtained.

Third Quarter Guiding Committee Meeting

Before this meeting, your Major Adviser will reconstitute your committee to include your

Adviser, future Major Professor, and one other interested faculty (can be some of the same

members as above). Suggestions from the student and major professor are advised as to

composition.

Check on progress –completing prerequisites, requirements? Maintaining a B average?

Are elective courses appropriate?

Form submitted to GGG by you after meeting is held and signatures obtained.

Fifth Quarter Guiding Committee Meeting (Same committee as for Third Quarter Meeting)

Verify that have completed/or will complete ALL coursework by end of 6th quarter

Suggest Qualifying Examination Committee Members

Verify that you have dissertation proposal- submit abstract

Form submitted to GGG by you after meeting is held and signatures obtained.

Advisers then assign QE members using suggestions from students as guide.

Official request for QE membership submitted to Graduate Studies for approval.

Annual Dissertation Committee Reports. After passing your QE, you are required to meet with

your Dissertation Committee at least one time per year. A form must be completed with signatures,

submitted to your adviser for signature, and then submitted to GGG office.

Graduate Studies Annual Progress Reports. Currently required to be submitted by GGG to

Graduate Studies by July 1. Requires adviser signature, submit to GGG office. This form will be emailed

to you later in the year.

Milestones

A. Qualifying Examination. This should be taken by the end of Winter Quarter of your third year.

Students typically take it Summer/Fall/Winter Quarter (7th, 8th quarter). Students must take the QE by

the 9th quarter to remain eligible for RAs, TAs.

B. Advancement to Candidacy. After passing the QE, you form a dissertation committee. This

step requires a form submitted to Graduate Studies and the Registrar. This committee has three

members, one of which is your Major Professor. The other two are chosen by you after consultation

with your Major Professor.

Page 5: Genetics Graduate Group Handbook - 2007

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GENETICS GRADUATE GROUP COURSE LIST

A. GGG Required Courses

1. Core Courses:

GGG201A (Fall Quarter) Advanced Genetic Analysis/Model Systems (5 units)

Lecture: TR 0900-1020 AM 101 Bowley Center Room

Discussion: Tuesday 12:10-2 PM 3 Wellman or

Wednesday 1:10-3 PM 101 Bowley Center Room

GGG 201B (Fall Quarter) Genomics (5 units)

Lecture: TR 10:30-11:50 AM 1344 Storer

Discussion: TR 6:10-8 PM 1137PLESC (Plant and Environmental Sciences)

GGG 201D (Winter Quarter) Quantitative and Population Genetics

GGG201C/ MCB 221C (Spring Quarter) Molecular Biology-

2. Seminar Course:

GGG 291 (Fall quarter) History of Genetics (2 units, CRN 57134)

GGG Seminar Courses

GGG293 (Spring quarter 2008) Seminar in Animal Genetics

GGG294 (Winter quarter 2008) Seminar in Human Genetics

GGG295 (Fall Quarter 2008) Seminar in Chromosome Biology

GGG297 (Winter quarter 2009) Seminar in Plant Genetics (Model Plants)

GGG298 (Fall quarter 2007) Seminar in Plant Genetics (Plant Breeding and

Biodiversity) (2 units)

B. GGG Rotation Laboratory Courses

GGG Laboratory courses:

GGG205-(Fall) Molecular Genetics Laboratory (Rotations)

GGG205-(Winter) Molecular Genetics Laboratory (Rotations)

GGG207L-(Fall, Winter, Spring) Research Methods in Plant Genetics Laboratory-

C. Other GGG courses

GGG210 (Fall 2007) Horizontal Gene Transfer-Cal Kado, Mike Syvanen (3 units)

GGG211 (Winter) Concepts in Human Genetics and Genomics

GGG220/VCR 220 (Winter) Genomics & Biotechnology of Plant Improvement Michelmore

GGG296 (Fall 2008) Science Professionalism and Integrity- Yoder (2 units)

GGG298 (Fall, Winter, Spring) Group Study

GGG299 (Fall, Winter, Spring) Research

GGG300 (Fall, Winter, Spring) Teaching in Genetics

Page 6: Genetics Graduate Group Handbook - 2007

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Additional Courses with a Genetic Component

General Genetics Upper Division Undergraduate

ANG 107 (Fall) Genetics and Animal Breeding

ANT 151 (Spring) Primate Evolution

ANT 152 (Winter) Human Evolution

AVS 103 (Spring) Avian Development and Genetics

BIS 101 (Fall, Winter, Spring) Genes and Gene Expression

MCB 121 (Winter, Spring) Molecular Biology of Eukaryotic Cells

MCB 162 (Fall) Human Genetics

MCB 163 (Winter) Developmental Genetics

MCB 164 (Winter) Advanced Eukaryotic Genetics

MIC 150 (Winter) Bacterial Genetics

MIC 170 (Spring) Yeast Molecular Genetics

Molecular Genetics

Graduate

ANG 211 (Spring) Genetic Engineering of Animals

ANG 212 (Winter) Sequence Analysis in Molecular Genetics

MCB 255 Molecular Mechanisms in Animal Development

MCB 256 (Fall ) Cell and Molecular Biology of Cancer

MCB 257 (Fall ) Cell Proliferation and cancer genes

MCB 262 (Winter ) Transgenic Expression Systems

MCB 263 (Winter) Biotechnology Fundamentals & Applications

MIC 200A (Fall) Biology of Prokaryotes

MIC 215 (Fall) Recombinant DNA

MIC 250 (Winter) Biology of Yeasts

MIC 263 (Spring) Principles of Protein-Nucleic Acid Interactions

MIC 298- maybe an official number come winter quarter (Winter 2005) Recombination

PBI 227 (Winter) Plant Molecular Biology

Upper Division Undergraduate

ANG111 (Winter) Molecular Biology Laboratory Techniques

BIS 102 (Fall, Winter, Spring) Structure and Function of Biomolecules

MCB 121(Winter, Spring) Molecular Biology of Eukaryotic Cells

MCB 161 (Winter) Molecular Genetics

MCB 160L (Fall, Winter, Spring) Principles of Genetics Laboratory

MCB163 (Winter) Developmental Genetics

MIC 170 (Spring) Yeast Molecular Genetics

Cytogenetics

Graduate

VCR 221 Vegetable Genomics

Upper Division Undergraduate

ANG101 (Spring) Animal Cytogenetics

Page 7: Genetics Graduate Group Handbook - 2007

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Additional Courses with a Genetic Component (continued)

Population Genetics

Graduate

AGR 221 (Spring) Advanced Plant Breeding

EVE 210 (Spring) Molecular Phylogenetic Analysis

PBG 200A (Fall) Principles of Population Biology

PGB 200B (Winter) Principles of Population Biology

PGB 200C (Spring) Principles of Population Biology

PBG 207 (Winter) Plant Population Biology

PBG 270 (Fall) Evolutionary Biology

PBG 290 (Fall, Winter, Spring) Seminar

Upper Division Undergraduate

ANT 153 (Winter) Human Biological Variation

EVE 102 (Fall) Population and Quantitative Genetics

Quantitative Genetics

Graduate

AGR 221 (Spring, not offered 2004-2005) Advanced Plant Breeding

ANG 204 (Spring) Theory of Quantitative Genetics

ANG 206 (Spring) Advanced Domestic Animal Breeding

Upper Division Undergraduate

ANG120 (Spring) Introduction to Statistical Genomics

EVE 102 (Fall) Population and Quantitative genetics

Evolution

Graduate

EVE 210 (Spring offered in alternate years) Molecular Phylogenetic Analysis

PBG 203 (Winter) Advanced Evolution

PBG 270 (Fall, Winter, Spring) Research Conference in Evolutionary Biology

Upper Division Undergraduate

ANT 151 (Spring) Primate Evolution

ANT 152 (Winter) Human Evolution

EVE 100 (Fall, Winter, Spring) Introduction to Evolution

EVE 103 (Winter) Phylogeny and Macroevolution

Physiological Genetics

Graduate

MCB221D (Winter) Cellular Biochemistry

Upper Division Undergraduate

NPB 131 (Fall) Physiological Genomics

Page 8: Genetics Graduate Group Handbook - 2007

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Additional Courses with a Genetic Component (continued)

Breeding

Graduate

AGR 221 (Spring) Advanced Plant Breeding

ANG 206 (Spring) Advanced Domestic Animal Breeding

GGG 220/VCR 220 (Winter) Genomics & Biotechnology of Plant Improvement

VCR 221 (Spring) Genomics and Breeding of Vegetable Crops

Upper Division Undergraduate

ANG 107 (Fall) Genetics and Animal Breeding

PLB 154 (Winter) Introduction to Plant Breeding

PLB 160 (Winter) Principles of Plant Biotechnology

Biotic Stresses in Plants

Graduate

PLP 210 (Fall) Biochemistry & Molecular Biology of Plant-Microbe Interaction

Upper Division Undergraduate

PLP123/PLB123/ENT123 (Fall-not offered 2004-2005 ) Plant-Virus Interaction

Human/Primate Genetics

Graduate

ANT 252 (Winter) Human Evolution Seminar

Upper Division Undergraduate

ANT 151 (Spring) Primate Evolution

ANT 152 (Winter) Human Evolution

ANT 153 (Fall) Human Biological Variation

ANT 157 (Winter) Anthropological Genetics

ANT 157L (Fall) Laboratory in Anthropological Genetics

MCB 162 (Winter) Human Genetics

Graduate Seminar Courses

ANT 252 (Winter) Human evolution Seminar

AVS 290 (Fall, Winter, Spring) Seminar in Avian Genetics, Physiology, etc.

BCM 291 (Fall, etc) Human Genetics Seminar

MIC 274 (Fall, Winter, Spring) Seminar in Genetics Recombination

MIC 275 (Fall, Winter, Spring) Journal Club in Recombination Genetics

ECL 208 (Winter) Issues in Conservation Biology

Page 9: Genetics Graduate Group Handbook - 2007

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Genetics Courses F07-S08

Fall 2007

Course Title Instructor # Units CRN#

GGG 201A Genetic Analysis Britt, AB 5 57125

Roth, JR 57126

LaSalle, JM

Bisson, LF

GGG 201B Genomics Cook, DR 5 57127

GGG 205 Molec Genetics Lab Lyons, LA 5 57128

GGG 207L Research Methods Teuber, LR 2.0-5.0 @

GGG 210 Horizontal Gene Transfer Syvanen, M 3 57131

GGG 291 Sem History Genetics Quiros, C 2 57134

GGG 296 Science Integrity Yoder, JI 1.0-5.0 @

GGG 298 Sem Plant Breeding and Biodiversity St. Clair 2 57197

GGG 299 Research 1.0-3.0 @

GGG 300 Teaching Genetics

Winter 2008

Course Title Instructor 5 26508

GGG 201D Quant & Pop Genet Famula, TR

Neale, D 5 26509

GGG 205 Molec Genetics Lab Syvanen, M 2.0-5.0 @

GGG 207L Research Methods 3 26512

GGG 211 Human Genetics Genomics Seldin, MF

Hagiwara, N

LaSalle, JM 2 26514

GGG 294 Sem Human Genetics Seldin, MF 1.0-5.0 @

GGG 298 Group Study 1.0-12.0 @

GGG 299 Research 1.0-3.0 @

GGG 300 Teaching Genetics

Spring 2008

Course Title Instructor 4 49240

GGG 201C Molecular Biology Heyer, WD 2.0-5.0 @

GGG 207L Research Methods 1.0-3.0 @

GGG 293 Sem Animal Genetics May, BP 1.0-5.0 @

GGG 298 Group Study 1.0-12.0 @

GGG 299 Research 1.0-3.0 @

GGG 300 Teaching Genetics

Page 10: Genetics Graduate Group Handbook - 2007

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Genetics Graduate Group

Expanded Guidelines for Qualifying Exam Procedures

This is a document for students, major professors and qualifying examination chairs

and committee members. All please read.

EXAM FORMAT AND PHILOSOPHY

All focus groups require preparation of a dissertation proposal and its defense at an oral examination. In

addition, all focus groups require examination in the four areas of Genetics as represented by the 4 core

courses at the same meeting. The Chromosome Biology Focus Group additionally requires preparation

and defense of a secondary proposal.

During the examinations, the emphasis of the exam should focus on determining whether the student

has acquired the intellectual research skills and the genetic knowledge base necessary to successfully

conduct independent research in the future. In this context it is important to view the proposals as an

intellectual exercise that provides one way to measure these skills. Rather than emphasizing the quantity

of work already accomplished or the quality of the data that have been generated, the proposal should

be used to measure the potential research skills of the student. By preparing a proposal the student

should demonstrate mastery of the following skills: (1) ability to identify and clearly define a research

topic that makes a substantial and novel contribution to genetic knowledge; (2) ability to focus the

proposed research around one or more testable scientific hypotheses; (3) ability to design and interpret

scientifically feasible experiments that will specifically test these hypotheses; (4) ability to review the

scientific literature in the proposal field to clearly define the relationship of the proposed research to

existing knowledge; (5) ability to integrate, where appropriate and feasible, various genetic approaches

(e.g. transmission, cytogenetic, quantitative genetics); and (6) ability to relate proposed experiments to

the biology of the organism.

It is critical for students, major professors and examining faculty to remember that the proposal

evaluation should not be viewed as an evaluation of the work of the major professor, or as a contract

for the work that will be ultimately completed for the dissertation. The dissertation committee will be

formally constituted after completion of the qualifying exam. Definition of the work that constitutes the

dissertation is by joint agreement of the student, the major professor and the other members of the

dissertation committee. The major professor may be involved in guiding the student during design of the

overall focus of the dissertation research topic, but the student will ultimately have the responsibility for

discussing the dissertation topic proposal in the examination and therefore should also have the

responsibility for crafting a proposal of the highest possible scientific quality. The content of the

proposal should therefore not be unduly influenced by grant or contract constraints of the major

professor that would prove detrimental to the ability of the student to defend the scientific soundness

and rigor of the proposed approaches. In other words, the role of the proposal as a mechanism to

demonstrate conceptual understanding and the ability to think and work independently in the field of

genetics should be emphasized over its role as a measure of specific accomplishments in the lab.

It is particularly important to maintain a focus on this role of the proposal(s) for students using that

exam format, as a demonstration of intellectual ability in the field of genetics when conducting

examinations on the alternate proposals. It is not appropriate to judge proposals using criteria that

would apply for extramural grant review panels, for example. The absolute feasibility of experimental

details is less important in this context than demonstration of a breadth in understanding of the field,

ability to analyze the important scientific questions in the field, and ability to propose reasonable

approaches to address those questions.

Page 11: Genetics Graduate Group Handbook - 2007

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In conducting research proposal sections of the examination, committees should try to emphasize two

areas: (1) general and specific knowledge related to the proposal area, and (2) intellectual research skills

of the student (e.g. methodological rationale, hypothesis testing and evaluation,

etc.). All areas of general genetic knowledge may not be adequately covered during the proposal

segment(s) of the examination, so it is advisable to reserve some time specifically for this task.

PREPARATION OF PROPOSAL(S)

CHOICE OF TOPICS. For students that will be preparing a dissertation proposal and an secondary (also

called alternate) proposal (where applicable) it is important to remember that the emphasis of the two

proposals must be clearly distinct and demonstrate mastery of a different set of genetic concepts and

tools. One purpose of the secondary proposal is to demonstrate breadth of knowledge in genetics and

additionally to allow the student the opportunity to formulate a completely independent proposal, not

related to or guided by the research occurring in the major professor's lab.

Students are asked to submit a one-page abstract of their dissertation proposal, and a title or brief

description of their alternate proposal along with their 5th quarter report forms. While this provides

guidance for the assignment of examination committee members, the topic should be discussed with and

approved by the Chair of the examination committee. The one-page abstract and alternate proposal

topics (where required) will be forwarded to the appointed chair of the qualifying exam committee. If

the student subsequently changes these proposal topics significantly, the student should again consult

with their examination chair as to the acceptability of the revised topic(s). Chairs may consult with

other committee members to reach a decision on the proposal topic suitability.

Examination committee members should not provide detailed comments on the specific content of

qualifying exam proposal(s) to the student prior to the examination itself. Exam committee members

should, however, review the proposal as soon as possible after receiving it from the student and

communicate any serious concerns about the overall structure and focus of the proposal(s) to the chair

of the committee. Appropriate concerns would include general issues such as absence of definition of

an appropriate scientific problem, defects in structuring proposal around testable hypotheses, failure to

analyze interpretation of possible experimental outcomes, etc. These general concerns should be

passed on to the student by the chair, providing a chance to correct these structural errors in the

proposal prior to potentially disastrous consequences in the exam itself. The exam date may need to be

readjusted if the corrected proposal will not be completed prior to two weeks before the exam is

scheduled. It is therefore extremely important that the students pay close attention to these aspects of

their proposals during preparation and that they distribute their proposals prior to the two-week

deadline so that this evaluation can be made in a timely fashion.

FORMAT FOR Ph.D. QUALIFYING EXAM RESEARCH PROPOSALS

The goal of each research proposal is to provide a substantial and original contribution to the field of

genetics. The scope should be similar to that of a two-year postdoctoral grant proposal. If an alternate

proposal is required, it should be in an area outside of those normally considered by the student's

research group. The topic and approaches of the alternate proposal must be distinct from those of the

thesis proposal. The student is to develop the alternate proposal independently, without input from the

major professor. The student should discuss the alternate topic with the qualifying exam committee

chair.

Written versions of both the dissertation research proposal and the alternate research proposal are to

be prepared by the student and distributed to the committee at least two weeks prior to the

examination.

Page 12: Genetics Graduate Group Handbook - 2007

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The format is that of a NIH postdoctoral fellowship proposal. Organize sections the research proposal

to answer these questions: (1) What do you intend to do? (2) Why is the work important? (3) What

have you already done? (4) How are you going to do the work? (5) References. DO NOT EXCEED 5

PAGES FOR SECTIONS 1-4.

(1) Specific Aims: What do you intend to do? (one-half page.)

Start with a paragraph containing a synopsis of the general problem addressed and clearly stating the

hypothesis to be tested. This is necessary for the specific aims to make sense. Then, list the specific

aims.

(2) Background and Significance: Why is the work important? (one page)

Briefly sketch the background to the proposal. Critically evaluate existing knowledge, and identify the

gaps that the project is intended to fill. State concisely the importance of the proposed research by

relating the specific aims to the broad, long-term objectives.

(3) Preliminary Studies: What has already been done? (one page).

Thesis research: describe the work you have already accomplished that is relevant to the proposal or

the work in your lab that forms the rationale for your proposal. Alternate proposal: describe the work

done by others that forms the rationale for the proposal.

(4) Experimental Design: How are you going to do the work? (2.5 pages).

List the aims again. Under each aim, explain the rationale for each experiment necessary to accomplish

the aim, the experimental design, the interpretation of different types of results, and necessary methods

(without intricate details). Include the means by which data will be collected, analyzed and interpreted.

Describe any new methodology and its advantage over existing methodologies. Discuss the potential

difficulties and limitations of the proposed procedures along with alternative approaches to achieve the

aims. Provide a tentative sequence for the investigation. At the end, summarize how your experimental

results will test your hypothesis.

(5) References: quote references in the text (Author[s], date) and then collect them in

alphabetical order at the end. Each citation must include the names of all authors, title of the article,

name of the book or journal, volume number, page numbers and year of publication.

PRESENTATION OF THE PROPOSAL DURING THE EXAMINATION

In order to reduce the emphasis on data already collected and to increase the emphasis on the

scholarly and general knowledge aspects of the exam, the student will not be allowed to use computer

slides or overhead projectors during their short presentation of the dissertation proposal. Students are

allowed and encouraged to use a brief outline on the blackboard to focus and direct their presentation.

THE ROLE AND RESPONSIBILITY OF THE EXAM CHAIR:

For the Chair- Prior to exam:

1. Confirm topics of dissertation proposal (and alternate where applicable) with student.

2. Communicate general concerns about the design of proposals from exam committee to the student.

3. Discuss exam format with student.

4. Remind committee members of the time and place of the exam if student has not already done so;

make sure committee members understand exam format and exam areas.

5. Make sure that you have appropriate paperwork. Graduate Studies sends the forms as email

attachments when you are notified of the QE application approval. If you want a copy of the

student’s transcript, please contact the graduate group office (Ellen).

Page 13: Genetics Graduate Group Handbook - 2007

12

For the Chair- During the Exam

1. Assure a fair examination of the student. Make sure examination has a break.

2. Bring appropriate student records relating to past academic work to the examination for

consideration by the committee.

3. Assure that all required areas in the examination are adequately covered, by monitoring the time

spent in questioning in each area and initiating movement to the remaining topics if necessary during

the exam. For all focus groups, make sure there is sufficient time for examination in the four core

areas and that approximately 1-1 1/2 hr is spent on the dissertation proposal. .For Chromosome

Biology Focus Group: sufficient time for examination of the secondary proposal.

4. Moderate discussion of evaluation of student performance after examination is completed. Allow all

committee members to express their evaluation of the student and vote.

For the Chair- After the Exam

1. Immediately after the final vote, communicate the outcome of the exam to the student.

2. Complete paperwork and submit to Ellen Picht in GGG office. She will forward to GS.

3. In the event of a "not pass", clearly communicate to the student verbally and in writing the opinion

of the committee and the requirements for converting a "not pass" to a "pass". A letter should be

written to Graduate Studies explaining in detail what needs to be done and this letter and the

information within must be discussed with the student. Please submit to Ellen Picht in GGG office

and she will forward to GS.

THE ROLE AND RESPONSIBILITY OF THE OTHER EXAM COMMITTEE MEMBERS

1. Set aside time to meet with the student prior to the examination to provide general suggestions

about preparing for the exam, useful material to review during exam study, etc.

2. Review the proposal(s) soon after receipt to evaluate general proposal design. Communicate

concerns to chair of committee as soon as possible.

3. Read proposal carefully prior to the exam date.

4. Conduct a fair and thorough examination of the student, covering intellectual skills necessary for

independent scientific research as well as specific knowledge in the areas related to the proposed

dissertation work and general knowledge in genetics. It is unreasonable to expect extensive

knowledge in your own particular area of expertise, unless it is closely related to the student’s exam

topics.

5. Remember that you are examining the student, not the major professor. The student's ability should

be evaluated independently of any particular characteristics of the major professor.

6. Use evaluation criteria appropriate for the academic "stage" of the student. Do not expect that a

large portion of research for the dissertation will have already been completed at the time of the

exam.

THE ROLE AND RESPONSIBILITY OF THE STUDENT

1. Arrange for a meeting of your guiding committee to complete the fifth quarter report form during

winter quarter of your second year. For this meeting, prepare a one-page abstract of your planned

dissertation proposal, emphasizing the scientific hypotheses/questions that your work will address

and the planned approaches to test those hypotheses. Define the general focus of your alternate

proposal/area, if appropriate. If an alternate proposal is required, provide a classification of the main

areas of emphasis of the dissertation proposal and the alternate proposal to demonstrate their

distinctiveness.

2. Contact the chair and each committee member to arrange for a time to hold the examination.

Arrange, or request the chair to help you arrange, a room reservation for the examination. In

general, exams do not extend beyond 3 hours but is useful to reserve the room for 1/2 hour

preceding and following the projected exam period.

3. Meet with the chair to verify your choice of proposal topic (and alternate topic, if applicable).

Notify chair if there is a significant change in these topics.

Page 14: Genetics Graduate Group Handbook - 2007

13

4. Make appointments as needed with each committee member to update them on your dissertation

proposal and alternate proposal topics and to discuss with them suggestions for study areas or

resources. But do not expect committee members to provide you with detailed lists of exact topics

or questions to study.

5. Provide committee members with your proposal(s) well in advance of the exam date and certainly

no later than 2 weeks prior to your exam, to allow communication about any general concerns

regarding the design and scientific soundness of your proposal(s). Do not expect your committee

members to give you detailed feedback on the specifics of your proposals.

Prepared by Educational Policy Committee (April/May 1996)

Jeanette Natzle (Chair), Abhaya Dandekar, Kathryn Radke, Marta Marthas, Thea Wilkins, Doug Shaw,

Anita Oberbauer, Ken Shaw

Updated by Judy Callis (April 2003) to reflect new focus group organization.

Updated by Judy Callis (Summer 2006) to remove affinity group requirements and change procedure

such that paperwork for QE is received by Ellen Picht and the chair must get the paperwork from GGG

office. Change in paperwork procedure Fall 2007. Forms now sent directly to committee chairs as

email attachments by Graduate Studies.

Page 15: Genetics Graduate Group Handbook - 2007

14

Focus Groups- 2007

Genetics Graduate Group

Focus Group Members Address Group Chair

Animal Genomics Danika Bannasch VM: Pop. Health & Repro. Holly Ernest

Mary Delany Animal Science

Holly Ernest Vet Genetics Lab

Tom Famula Animal Science

Sree Kanthaswamy Vet Genetics Lab

Dietmar Kueltz Animal Science

Leslie Lyons VM: Pop. Health & Repro.

Bernie May Animal Science

Juan Medrano Animal Science

Jim Murray Animal Science

Anita Oberbauer Animal Science

Alison Van Eenennaam Animal Science

Chromosome

Biology Sean Burgess MCB Wolf-Dietrich Heyer

Ken Burtis MCB

Anne Britt Plant Biology

Frederic Chedin MCB

Hongwu Chen Biological Chemistry

Jan Dvorak Plant Sciences

JoAnne Engebrecht MCB

Wolf-Dietrich Heyer Microbiology

Neil Hunter Microbiology

S. Kowalczykowski Microbiology

Ken Kaplan MCB

Hsing-Jien Kung Biological Chemistry

Charles Langley EVE

Janine LaSalle Microbiology

Martin Privalsky Microbiology

David Segal Med Pharm. Tox.

Michael Syvanen Micro. & Immuno.

Human Genetics Gino Cortopassi VM: Molecular Bioscience Michael Seldin

Nobuko Hagiwara Med: Cardiovascular Med.

Liping Huang Nutrition

Hsing-Jien Kung UCD Cancer Center

Janine LaSalle Microbiology

Leslie Lyons

Vet Med: Pop. Hlth. &

Repro

Frederick Meyers Internal Medicine: MED

Page 16: Genetics Graduate Group Handbook - 2007

15

Maria Mudryj Med. Micro. & Immuno.

Michael Seldin Med. Biological Chem.

Craig Warden Rowe Program

Reen Wu Research Bio. & Medicine

Mark Zern Int Med: Transplant

Chengji Zhou Cell Bio. & Human Anat.

Model Plants Steffen Abel Plant Sciences Chuck Gasser

Diane Beckles Plant Sciences

John Bowman Plant Biology

Anne Britt Plant Biology

Judy Callis MCB

Douglas Cook Plant Pathology

Chuck Gasser MCB

John Harada Plant Biology

Stacey Harmer Plant Biology

Dan Kliebenstein Plant Sciences

William Lucas Plant Biology

Julin Maloof Plant Biology

Richard Michelmore Plant Sciences/ MCB

Alan Rose MCB

Neelima Sinha Plant Biology

Venkatesan Sundaresan Plant Biology

Valerie Williamson Nematology

John Yoder Plant Sciences

Plant Breeding and

Biodiversity Roger Chetelat Plant Sciences Dina St.Clair

Douglas Cook Plant Pathology

Jorge Dubcovsky Plant Sciences

Paul Gepts Plant Sciences

Robert Gilbertson Plant Pathology

Marie Jasieniuk Plant Sciences

Dan Kliebenstein Plant Sciences

F. Thomas Ledig

Environmental

Horticulture

Julin Maloof Plant Biology

David Neale Plant Sciences

Dan Parfitt Plant Sciences

Doug Shaw Plant Sciences

Dina St.Clair Plant Sciences

Thomas Tai Plant Sciences

Larry Teuber Plant Sciences

Andy Walker Viticulture

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16

ANIMAL GENOMICS FOCUS GROUP (revisions Sept 2007) as noted

OBJECTIVES

The Animal Genomics (AG) focus group within the Genetics Graduate Group (GGG) will bring

together faculty who are active in this area of research to enhance the training opportunities in this area.

Animal Genomics is defined as research that either utilizes global, genome-wide approaches or

information derived from such approaches to address questions about the causes of individual

differences in fitness in natural or agricultural environments, genome organization, evolution, or gene

function in animals.

ACTIVITIES

The AG focus group will:

provide visibility for recruiting students interested in this area, develop and maintain a webpage

focused on the faculty and research programs within the Animal Genomics focus group,

allow coordination of research and training in Animal Genomics,

set the specialist curricula as below,

conduct a biweekly journal club/seminar series focused on Animal Genomics,

organize a GGG seminar once every two years focused on Animal Genomics,

assist in the function and administration of the GGG by providing representatives to serve on GGG

standing committees,

provide the framework for training grants.

ADMINISTRATION

The AG focus group will be administered by a group leader in consultation with the whole membership.

There will be no standing committees. Administration (recruiting, advising, etc.) will be through

representation on GGG standing committees. Focus group policy will be decided by the whole focus

group membership.

ELECTION OF FOCUS GROUP LEADER

The membership will elect a leader by an e-mail ballot of the whole membership. A simple majority of

those voting will decide the leadership. The leadership will usually be for a term of three years. A

majority vote of the membership can request an earlier election.

MEMBERSHIP

Membership is open to anyone who wishes to actively participate in the AG focus group for the first

year. At the end of the first year, the membership will self assess itself according to the criteria below.

Membership will be reviewed every three years subsequently by the whole membership. A majority of

those voting will be required for continued membership.

CRITERIA FOR CONTINUED MEMBERSHIP

Maintenance of an active research program in the area of animal genomics as evidenced by:

Publications in the area of comparative and/or functional animal genomics in each of the previous

three years.

Sufficient funding to support genomics research.

Activity in the AG focus group as evidenced by:

o representing the AG focus group on a GGG standing committee,

o teaching in a GGG core course or the AG focus group GGG seminar,

o teaching a course directly relevant to the AG focus group,

o sustained participation in the AG journal club, seminar and colloquium.

Sustained activity in at least one of these four activities is required unless there are significant mitigating

administrative circumstances (such as being department chair).

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MEMBERSHIP APPLICATION [Added 9/03]

Once the Executive Committee of the GGG approves admission of a faculty member to GGG, the application

packet for faculty interested in the AG focus group will be forwarded to the AG focus group membership for

voting. Potential members will be evaluated on the above criteria for membership in 1) above and the potential

and willingness to be active within the focus group as noted in 2) above. Membership acceptance requires a

majority of approval by current members.

STUDENT CURRICULUM

Courses:

All students will take the GGG core courses and other courses required of all GGG students. In

addition, students will take at least two courses from the course list in their area of specialization from

the restricted electives list and at least one additional graduate course to provide breadth of education.

The required GGG courses and two restricted elective courses will be taken for a letter grade.

Students will also take the AG focus group sponsored seminar plus one other GGG approved seminar

in addition to GGG291. All students will TA a genetics course prior to advancing to candidacy and will

be encouraged to enroll in GGG300.

Rotations:

In-coming students will not be required to rotate. If needed, rotations will be organized on an individual

basis.

Qualifying Examinations:

The format of the qualifying examinations will be the presentation and defense of a research proposal

plus a specific defense of each of the four areas covered by the core courses. The chair of the qualifying

examination will be from the membership of the AG focus group. [Added 9/03]

REVISION OF OPERATING PROCEDURES

These operating procedures may be revised at anytime by a majority vote of the membership and

subject to ratification by the GGG executive committee.

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GGG Animal Genomics Focus Group course list

In addition to taking all of the required GGG core courses and seminars, each student will complete a

minimum of two courses from the following list, plus one additional graduate level course as approved

by the Guiding Committee. (Substitutions for one course can be made for a course approved by the

Guiding Committee).

ANG 204 Theory of Quantitative Genetics

ANG206 Advanced Domestic Animal Breeding

ANG 208 Estimation of Genetic Parameters

ANG 212 Sequence Analysis in Molecular Genetics

AVS 220/MCB257 Cellular Proliferation of Oncogenes

BCM 222 Mechanisms of Translational Control

ECL 208 Conservation Biology

ECL242/PHR242 Ecological Genetics (ECL298/PHR298 for Winter 2008) [Added 9/07]

ENT 212 Molecular Biology of Insects and Insect Viruses

EPI 205A Principles of Epidemiology

EVE 210 Molecular Phylogenetic Analysis

EVE 211 Applied Phylogenetics

GGG 210 Horizontal Gene Transfer

MCB 255 Molecular Mechanisms of Animal Development

MCB 262 Transgenic Expression Systems

MCP 255/ABG 255 Stress Physiology [Added 6/07]

MIC 215 Recombinant DNA

MIC215L Recombinant DNA Laboratory

MIC 263 Principles of Protein-Nucleic Acid Interactions

PBG 200A, B, C Principles of Population Biology

PBG 203 Advanced Evolution

PGG 200L Animal Cell Culture Laboratory

Faculty membership in the Animal Genetics Focus Group [Updated 9/07]

1. Danika Bannasch VM:Population Health and Reproduction

2. Mary Delany Animal Science

3. Holly Ernest VM:Population Health and Reproduction

4. Thomas Famula Animal Science

5. Sree Kanthaswamy California National Primate Research Center

6. Dietmar Kueltz Animal Science

7. Leslie Lyons VM:Population Health and Reproduction

8. Bernie May Animal Science

9. Juan Medrano Animal Science

10. Jim Murray Animal Science

11. Anita Oberbauer Animal Science

12. Alison Van Eenennaam Animal Science

Page 20: Genetics Graduate Group Handbook - 2007

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Chromosome Biology Focus Group

Objectives:

The Chromosome Biology Focus Group (ChromBio FG) constitutes itself within the Genetics Graduate

Group as a group of faculty with a common interest in all aspects of chromosome biology, particularly in

DNA repair, DNA recombination, DNA replication, chromosome segregation and chromosome

dynamics using a variety of scientific approaches and experimental model systems.

Activities:

The ChromBio FG will:

provide visibility for recruiting students interested in this area,

develop and maintain a webpage focused on the group,

allow coordination of research and training in ChromBio FG,

set the specialist curricula as below,

organize a GGG seminar once every two years focused on ChromBio FG,

assist in the function and administration of the GGG by providing representatives to serve on GGG

standing committees,

conduct a journal club focused on ChromBio FG,

provide the framework for training grants.

Administration:

The ChromBio FG focus group will be administered by a group leader in consultation with the whole

membership. There will be no standing committees. Administration (recruiting, advising, etc.) will be

through representation on GGG standing committees. Focus group policy will be decided by the whole

membership. The Operating Procedures can be changed or amended by a simple majority of its

members.

Election of Focus Group Leader:

The membership will elect a leader by an e-mail ballot of the whole membership. A simple majority of

those voting will decide the leadership. The leadership will usually be for a term of three years. A

majority vote of the membership can request an earlier election.

Membership:

Membership is open to anyone who wishes to actively participate in ChromBio FG for the first year. At

the end of the first year, the membership will self assess itself according to the criteria below.

Membership will be reviewed every three years subsequently by the whole membership. A majority of

those voting will be required for continued membership.

Criteria for Membership:

1) Maintenance of an active research program in the above mentioned areas of chromosome biology, as

evidenced by:

a) peer-reviewed publications and

b) extramural funding.

These criteria are suspended for new faculty members that need time to publish and to attract funding

and will not be applied until publications and funding can reasonably be expected.

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2) Activity in the ChromBio FG as evidenced by:

a) representing the ChromBio FG on a GGG standing committee,

b) teaching a GGG core course or the ChromBio GGG seminar,

c) teaching a course directly relevant to the ChromBio FG,

d) sustained participation in the ChromBio journal club MIC275.

Sustained activity in at least one of these four activities is required unless there are significant mitigating

circumstances.

Student Curriculum:

The ChromBio FG establishes the following minimum curriculum for its students:

The four GGG core courses and other courses required for GGG students

GGG291 History of Genetics

The group requires that students rotate in four laboratories before deciding which laboratory they

join. It is encouraged, but not required, that students rotate in laboratories of ChromBio FG faculty.

One quarter Teaching Assistantship (TA) in a course of the GGG curriculum prior to the qualifying

examination. Students are encouraged to enroll in GGG300.

MIC275 Seminar in DNA Repair and Recombination (every quarter). This course will be developed

further and/or alternated with a GGG295 seminar (for a grade) to be offered annually or biannually

as a ChromBio FG seminar.

MIC263 Protein:Nucleic Acids Interactions (for a grade).

One additional graduate level course (for a grade) in a different area to encourage diversity in the

educational experience.

Qualifying Examinations:

The purposes of the Qualifying Examination are twofold: 1) to determine that the student has

acquired sufficient knowledge of genetics, in breadth and depth, and 2) to determine that the student has

identified a dissertation research topic that asks a significant question in genetics. The latter includes

demonstration that the student has completed a literature review of that topic, has identified a set of

achievable goals and has designed appropriate experimental approaches to accomplish those goals. The

dissertation research part of the exam is meant to be a proposal, not a research progress report. Finally,

the student's previous academic record, performance on specific parts of the examination, and overall

performance/potential for scholarly research will be evaluated in determining the outcome of the

examination.

Qualifying Examination Committees will consist of five faculty members. The Chair and preferably

two other members of the committee will be members of ChromBio FG, at least one of whom must

have agreed to serve on thesis committee of the student. Two other faculty who are not members of

ChromBio FG will be appointed by the pertinent GGG standing committee. The five members of the

Qualifying Examination Committee will represent the four core areas of GGG as covered in the core

courses (Advanced Genetic Analysis, Comparative and Functional Genomics, Molecular Genetics,

Transmission, Population and Quantitative Genetics). The leader of ChromBio FG will recommend to

the Advisors committee which ChromBio FG members serve on a qualifying examination committee.

The chair of the Qualifying Examination Committee is expected to ensure that a student receives a fair

examination. Qualifying Examination Committees may not include the major professor who will serve as

chair of the student's dissertation committee.

Students will be informed of the prospective composition of the Qualifying Examination Committee, and

will be asked to confer with their major professor to inform their graduate advisor of any concerns with

the committee composition. With this input taken into account, the advisors formally recommend to

Graduate Studies the composition of the Qualifying Examination Committee. Committees will be

appointed by the Dean of Graduate Studies. Copies of the approved petition are sent to the student, the

chair of the examining committee, and the GGG Program Liaison. Students must notify all members of

their examination committee that they have been appointed. This is important - for example, if a faculty

member will be on sabbatical and unable to serve, the exam committee must be reconstituted through

the GGG Student Affairs Committee and Graduate Studies.

Page 22: Genetics Graduate Group Handbook - 2007

21

Scheduling the Qualifying Examination. All Ph.D. candidates are expected to take their Qualifying

Examination before or during their eighth quarter following admission into the program (i. e. the Winter

Quarter of the third year), unless a prior waiver is approved in writing by ChromBio FG. It is strongly

encouraged that students take the Qualifying Examination before the onset of the seventh quarter

following admission (i.e. before the Fall quarter of the third year).

Format of the Qualifying Examination. The Qualifying Examination will consist of a dissertation

research proposal, a secondary proposal, and an examination in the four core subject areas (Advanced

Genetic Analysis, Comparative and Functional Genomics, Molecular Genetics, Transmission, Population

and Quantitative Genetics). Candidates will be expected to submit a written dissertation proposal and

an independent secondary proposal to their committee at least one week prior to the oral examination

(see below). During the qualifying examination only a chalk/white board is to be used.

The Dissertation Proposal. The goal of the dissertation research proposal is to provide a substantial

and original contribution to the field of genetics. The scope should be similar to that of a grant proposal.

Written versions of the thesis research proposal are to be prepared by the student and distributed to

the committee at least one week prior to the examination. The format is that of an NIH postdoctoral

fellowship proposal. Organize sections 1-5 of the research proposal to answer these questions: (1)

Specific aims. What do you intend to do? (2) Background and significance. Why is the work important?

(3) Preliminary studies. What have you already done? (4) Research design and methods. How are you

going to do the work? (5) References. DO NOT EXCEED 5 PAGES FOR SECTIONS 1-4. The following

distribution for length is recommended:

(1) Specific aims. State briefly the broad, long-term objectives of the work. Then state the specific

purposes of the proposed research. One-half page is recommended.

(2) Background and significance. Briefly sketch the background to the proposal. Critically evaluate

existing knowledge, and identify the gaps that the project is intended to fill. State concisely the

importance of the proposed research by relating the specific aims to the broad, long-term objectives.

One page is recommended.

(3) Preliminary studies - thesis research only. Describe the work you have already accomplished that

is relevant to the proposal. A maximum of one page is recommended.

(4) Research design and methods. Outline the experimental design and the procedures to be used

to accomplish the specific aims. Include the means by which data will be collected, analyzed and

interpreted. Describe any new methodology and its advantage over existing methodologies. Discuss the

potential difficulties and limitations of the proposed procedures along with alternative approaches to

achieve the aims. Provide a tentative sequence for the investigation. Although no specific number of

pages is recommended for this section, the total for sections 1-4 should not exceed 5 pages.

(5) References. Each citation must include the names of all authors, title of the article, name of the

book or journal, volume number, page numbers and year of publication.

The Secondary Proposal. The goal of the secondary proposal is that the candidate develops an

original hypothesis and suitable experimental tests of this hypothesis in an area independent of the

dissertation proposal. The candidate is free in the choice of topic but this choice needs approval by the

chair of the Qualifying Examination Committee. The format is identical to that of the dissertation

proposal.

Page 23: Genetics Graduate Group Handbook - 2007

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ChromBio FG students may meet with each committee member to discuss his or her expectations for

the examination. This meeting should not be not a pre-examination of the research proposals. Students

should not ask for, nor should the committee members provide, comments on weaknesses, potential

problems and errors in the research proposals.

Revision of operating procedures

These operating procedures may be revised at anytime by a majority vote of the membership and

subject to ratification by the GGG executive committee.

Approved by the membership on August 8, 2002.

The present membership list is:

Sean M. Burgess, Assistant Professor of Molecular and Cellular Biology

Ken C. Burtis, Professor of Genetics

Anne B. Britt, Associate Professor of Plant Biology

Frederic Chedin, Professor of Molecular and Cellular Biology

Hongwu Chen, Professor of Biological Chemistry

Jan Dvorak, Professor of Plant Sciences

JoAnne Engebrecht, Professor of Molecular and Cellular Biology

Wolf-Dietrich Heyer, Professor of Microbiology

Neil Hunter, Professor of Microbiology

Ken B. Kaplan, Assistant Professor of Molecular and Cellular Biology

Stephen C. Kowalczykowski, Professor of Microbiology

Hsing-Jien Kung, Professor of Biological Chemistry

Charles H. Langley, Professor of Evolution and Ecology

Janine M. LaSalle, Assistant Professor of Microbiology and Immunology

Martin L. Privalsky, Professor of Microbiology

David Jay Segal, Professor of Medical Pharmacology and Toxicology

Michael Syvanen, Professor of Microbiology and Immunology

Page 24: Genetics Graduate Group Handbook - 2007

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Human Genetics Focus Group

Statement of Mission

The GGG Human Genetics Focus Group provides students the opportunity for specialized

training in human genetics and genomics. The faculty members are dedicated to developing and

applying genetic information and methods towards understanding physiologic and

pathophysiologic human biology. Investigators are using human and/or model mammalian

species for these studies. The upper level courses taught by our faculty are centered on

understanding the concepts application of genetic tools towards defining the molecular basis of

human disease susceptibility and disease progression. These include molecular and cytogenetic

techniques as well as informatics, and statistical methodology and theory. Individual faculty

members have expertise in these broad topics as well as in transcription regulation, signaling

circuits, comparative genomics and quantitative trait analysis of complex genetic disease.

Members of this focus group are investigating a wide array of specific diseases. These include a

variety of cancers, obesity, diabetes, cardiovascular disease, autoimmune diseases, Rett

syndrome, and mitochondrial diseases. In addition to direct analysis of human disease,

applicable animal models of human disease being developed and studied include those in

nonhuman primates, cats and the mouse.

ACTIVITIES

The HG focus group will:

provide visibility for recruiting students interested in this area,

develop and maintain a webpage focused on the faculty and research programs within the Human

Genetics focus group,

allow coordination of research and training in Human Genetics,

set the specialist curricula as below,

conduct a biweekly journal club/seminar series focused on Animal Genomics,

organize a GGG participatory seminar course offered each years focused on Human Genetics,

assist in the function and administration of the GGG by providing representatives to serve on GGG

standing committees,

provide the framework for training grants.

ADMINISTRATION

The HGG focus group will be administered by a group leader in consultation with the whole

membership. There will be no standing committees. Administration (recruiting, advising, etc.) will be

through representation on GGG standing committees. Focus group policy will be decided by the whole

membership.

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ELECTION OF FOCUS GROUP LEADER

The membership will elect a leader by an e-mail ballot of the whole membership. A simple

majority of those voting will decide the leadership. The leadership will usually be for a term of three

years. A majority vote of the membership can request an earlier election.

Faculty Membership

Membership in GGG and active research in human or mammalian genetic models.

During the first year membership will be open to anyone who wishes to actively participate in

the HGG focus group for the first year. At the end of the first year, the membership will self

assess itself according to the criteria below. Membership will be reviewed every three years

subsequently by the whole membership. A majority of those voting will be required for

continued membership.

CRITERIA FOR MEMBERSHIP

1. Maintenance of an active research program in the area of comparative and/or function plant genomics

as evidenced by:

a) evidence of significant intellectual contributions to the field, for example, an average of at least two

peer-reviewed publications in the area of comparative and/or functional genomics in each of the

previous three years.

b) sufficient funding from competitive sources to support genomics research.

These criteria are suspended for new faculty members that need time to publish and to attract funding

and will not be applied until publications and funding can reasonably be expected.

2. Activity in the HGG focus group as evidenced by:

a) representing the HGG focus group on a GGG standing committee,

b) teaching a GGG core course, an HGFG seminar,

c) teaching a course directly relevant to the C&FPG focus group,

Sustained activity in at least one of these four activities is required unless there are significant mitigating

administrative circumstances (such as being department chair).

Course Requirements

1. GGG core courses

2. 3 Credit Participatory Seminar Series:

3. Upper level Seminar courses (3 required): Students will be encouraged to enroll in at

least one seminar course that focuses on human genetics (e.g. Human Genetics Seminar

BCM 291, Molecular Medicine BCM 214).

4. History of Genetics (required)

5. Two additional upper level courses are required.

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Students will select from a list of courses approved by the HGG

Currently these include:

ANG 204 Theory of Quantitative Genetics

ANG 208 Estimation of Genetic Parameters

AVS 220/MCB257 Cellular Proliferation of Oncogenes

BCM 222 Mechanisms of Translational Control

EPI 205A Principles of Epidemiology

EVE 210 Molecular Phylogenetic Analysis

EVE 211 Applied Phylogenetics

MCB 255 Molecular Mechanisms of Animal Development

MCB 262 Transgenic Expression Systems

MIC 215 Recombinant DNA

MIC215L Recombinant DNA Laboratory

MIC 263 Principles of Protein-Nucleic Acid Interactions

PBG 200A, B, C Principles of Population Biology

PBG 203 Advanced Evolution

PGG 200L Animal Cell Culture Laboratory

NPB 131 Genome Biology

TA Responsibilities

Students will be expected to fulfill a single quarter of TA experience that are an integral part of

graduate school education and preparation for a career in academics. To be compatible with NIH MSTP

guidelines, PSTP students are not required but are strongly encouraged to participate.

Rotations

Students will be strongly encouraged but not absolutely required to participate in 3 to 4

laboratory rotations (GGG205). Rotations can be either 5 or 10 weeks . A written and oral

presentation are required for credit and evaluation. In addition, they will be strongly encouraged that

one of these labs should be of a junior faculty’s (assistant professor) lab.

Qualifying Examinations

The format of the qualifying examinations will be of a single research proposal describing the

proposed thesis project followed by a specific defense of each of the four areas covered by the core

courses.

REVISION OF OPERATING PROCEDURES

These operating procedures may be revised at anytime by a majority vote of the membership

and subject to ratification by the GGG executive committee.

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GENETICS OF MODEL PLANTS FOCUS GROUP

OBJECTIVES

The Genetics of Model Plants (GMP) focus group within the Genetics Graduate Group (GGG)

will bring together faculty who are active in this area of research to enhance the training opportunities

in this area.

Genetics of model plants is defined as research that employs genetic approaches utilizing

Arabidopsis thaliana, maize, tomato and other plants as model organisms to answer fundamental biological

questions.

ACTIVITIES

The GMP focus group will:

provide visibility for recruiting students interested in this area,

develop and maintain a webpage focused on the group,

allow coordination of research and training in GMP,

set the specialized curricula as below,

organize a GGG seminar once every two years focused on GMP,

assist in the function and administration of the GGG by providing representatives to serve on GGG

standing committees,

conduct a journal club focused on GMP,

provide the framework for training grants.

ADMINISTRATION

The GMP focus group will be administered by a group leader in consultation with the whole

membership. There will be no standing committees. Administration (recruiting, advising, etc.) will be

through representation on GGG standing committees. Focus group policy will be decided by the whole

membership.

ELECTION OF FOCUS GROUP LEADER

The membership will elect a leader by an e-mail ballot of the whole membership. A simple

majority of those voting will decide the leadership. The leadership will usually be for a term of three

years. A majority vote of the membership can request an earlier election.

MEMBERSHIP

Membership is open to anyone who wishes to actively participate in the GMP focus group for

the first year. At the end of the first year, the membership will self assess itself according to the criteria

below. Membership will be reviewed every three years subsequently by the whole membership. A

majority of those voting will be required for continued membership.

CRITERIA FOR MEMBERSHIP

1) Maintenance of an active research program as evidenced by:

a) significant peer-reviewed publications in the area of genetics of plant model systems

b) adequate funding from competitive sources to support such research.

These criteria will be suspended for new faculty members who will be given reasonable time to publish

and to attract funding to meet the requirement.

2) Activity in the GMP focus group as evidenced by:

a) representing the GMP focus group on a GGG standing committee,

b) teaching a GGG core course or the GMP focus group GGG seminar,

c) teaching a course directly relevant to the GMP focus group,

d) sustained participation in an GMP journal club.

Sustained effort in at least one of these four activities is required unless there are significant mitigating

circumstances (such as being department chair).

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STUDENT CURRICULUM

Courses:

All students will take the core courses and other courses required of all GGG students,

including GGG 291 (History of Genetics). There is a requirement for a minimum of 3 courses in

addition to the core. Two courses are to be selected from a list approved by the GMP focus group

(attached) to provide training in the study of model plants, or in topics applicable to the study of model

plants. One course should have a molecular genetic emphasis, and one should focus on plants as the

experiment systems. In some cases, a single course can satisfy both these requirements. The student is

encouraged to consider courses with computational emphases. One additional graduate level course,

designed to encourage diversity in educational experience, is required. This course should be chosen in

consultation with your major professor and academic adviser, and requires adviser approval. These

three courses will be taken for a grade.

Seminars:

Students will also take the GMP focus group sponsored seminar, plus one other seminar in

addition to GGG291. All students will TA a genetics course prior to advancing to candidacy and will be

encouraged to enroll in GGG300.

Rotations:

In-coming students will be strongly encouraged but not absolutely required to rotate through at

least three labs during their first two quarters before deciding on a home lab. In addition, they will be

strongly encouraged that one of these labs should be in a junior faculty’s (assistant professor) lab.

Qualifying Examinations:

The format of the qualifying examinations will consist of a single research

proposal describing the proposed thesis research followed by an oral examination which will include

each of the four areas covered by the core courses.

REVISION OF OPERATING PROCEDURES

These operating procedures may be revised at anytime by a majority vote of the membership

and subject to ratification by the GGG executive committee.

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Genetics of Model Focus Group Restricted Elective Course List

AGR 221 Advanced Plant Breeding Teuber Spring

ECS 124 Theory and Practice of Bioinformatics Gusfield Spring

EVE 103 Phylogeny and Macroevolution Sanderson Winter

EVE 210 Molecular Phylogenetic Analysis Nadler, Sanderson

EVE 240 Paleobotany and Angiosperm Evolution Doyle Winter

GGG 220/

VCR 220

Genomics & Biotechnology of

Plant Improvement

Michelmore Winter

MIC 215 Recombinant DNA Privalsky Fall

MIC 262 Advanced General and Molecular Virology Bruening, Manning,

Luciw

Spring

MIC 263 Principles of Protein-Nucleic Acid Interactions Kowalczykowski Spring

PBI/MCB

126

Plant Biochemistry Abel/Callis Spring

PBG 203 Advanced Evolution Gottlieb Winter

PBI 208 Plant Hormones & Regulators Abel W-Odd 03

PBI 218A Advanced Concepts in Plant Cell Biology:

Cell Biogenesis

Lucas Winter (even yrs)

PBI 218B Advanced Concepts in Plant Cell Biology:

Transduction

Spring (odd yrs)

PBI 219 Reproductive Biology of Flowering Plants staff F-Odd

PBI 220 Plant Development Biology Bowman/Sinha Spring (odd)

PBI 227 Plant Molecular Biology Sinha, Britt W

VCR 221 Genomics and Breeding of Vegetable Crops Quiros Spring

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GENERAL GENETICS FOCUS GROUP

MISSION- The General Genetics Focus Group consists of all faculty in GGG. This focus group’s

mission is to provide a broad training in genetics. The requirements and operating procedures not

outlined here can be found in the GGG bylaws document.

ADMINISTRATION- The chair of the Genetics Graduate Group is the Chair of the General

Genetics Focus Group. Admission to the Genetics Graduate Group in essence means admission to the

General Genetics Graduate Group.

PHD COURSE REQUIREMENTS

1. a) Core Courses

i. GGG 201A, Advanced Genetic Analysis

ii. GGG 201B, Comparative and Functional Genomics

iii. GGG 201C, Molecular Genetics

iv. GGG 201D, Transmission, Population and Quantitative Genetics

b) Seminar Course

i. GGG 291, History of Genetics

2. Additional requirements to be approved by the academic adviser. These courses must be taken for a

letter grade.

a) Two GGG seminar courses, one a GGG 29X, and an additional seminar course approved by the

adviser

b) Two courses, at least one at the graduate level aim, both to provide depth in the general area of

proposed dissertation research

c) At least one additional graduate level course to encourage diversity in educational experience.

3. Laboratory Rotation Programs

Rotations are encouraged but not required. Ph.D. students may enter the GGG committed to a specific

faculty member or may enter unassigned and rotate through three or four laboratories during their first

two quarters prior to deciding on a faculty sponsor. If a student enters uncommitted, then they must

enroll in two quarters of GGG205.

4. TA Requirement

Students are required to serve as a teaching assistant for at least one genetics-oriented lecture or

laboratory course prior to advancing to candidacy in order to gain experience in teaching genetics. A

list of appropriate courses that fulfill this requirement will be assembled and approved by the Advising

Committee. The Advising Committee will have the discretion to approve particular courses for

individual students on ad hoc basis.

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MS DEGREE REQUIREMENTS

Advising

Each Masters student will be assigned to an adviser by the Advising Committee and a Guiding

Committee consisting of the major professor, the graduate advisor, and a third member of the faculty.

The academic curriculum and progress of each M.S. student will be followed by a guiding committee

consisting of the major professor, the adviser, and a third member of the faculty chosen by the student

in consultation with their major professor. When a thesis committee is chosen for a Plan I student, the

Guiding Committee will be discontinued.

Rotation Programs: M.S. students will not participate in rotation programs.

Curriculum

The normative time for a M.S. degree is two years. Students judged by the Advising Committee of the

GGG to be making inadequate progress towards the degree will be recommended to Graduate

Division for suspension from the program. Courses and other components of the program chosen to

fulfill the M.S. requirement must form an integrated plan to meet the individual student's objectives.

This plan will be developed by the Guiding Committee. Course work will include the following:

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Plan I: Thesis Option

Course work

a) Graduate Studies requirements:

At least 30 quarter units in residence at UC Davis. At

least 12 of the 30 units must be in graduate level

courses.

b) GGG requirements:

1) Core courses: GGG201A

Advanced Genetic Analysis

and at least two of:

GGG201B Comparative and Functional Genomics,

GGG201C Molecular Genetics

GGG201D Transmission, Population and Quantitative

Genetics

All core courses must be completed with a grade B or

better.

2) Group seminar (GGG292, 293, 295 or 297),

including one of the following:

Developmental Genetics

Cytogenetics

Quantitative Genetics

Population, Evolutionary and Ecological

Genetics

Animal Genetics

Molecular Genetics

Plant Genetics

3) Other courses: At least 18 of the 30 unit

requirement must be fulfilled by courses (no 299 units);

15 units must be in genetics-related courses.

c) Focus Group requirements:

At present there are no specific Focus Group

requirements. Focus Groups may, at some time in the

future, impose such requirements as are within the

general guidelines imposed by the Graduate Division.

Plan II: Course Option

Course work

a) Graduate Studies requirements:

At least 36 quarter units in residence at UC Davis. At

least 18 of the 36 units must be in graduate level

courses.

b) GGG requirements:

4. Core courses: GGG201A

5. Advanced Genetic Analysis

6.

and at least two of:

GGG201B Comparative and Functional Genomics,

GGG201C Molecular Genetics

GGG201D Transmission, Population and Quantitative

Genetics

All core courses must be completed with a grade B or

better.

2) Group seminar (GGG292, 293, 295 or 297),

including one of the following:

Developmental Genetics

Cytogenetics

Quantitative Genetics

Population, Evolutionary and Ecological

Genetics

Animal Genetics

Molecular Genetics

Plant Genetics

3) Other courses: At least 27 of the 36 unit

requirement must be fulfilled by courses (no 299 units);

21 units must be in genetics-related courses.

4) 299 (Research): At least 6 units of either Group

study (GGG298) or research (GGG299) are required.

A written report of 10 pages or longer following the

style of either a review or research paper in a scientific

journal in the field must be submitted to and approved

by the examining committee.

c) Focus Group requirements:

At present there are no specific Focus Group

requirements. Focus Groups may, at some time in the

future, impose such requirements as are within the

general guidelines imposed by the Graduate Division

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32

Masters Thesis

The thesis committee is appointed after the student

submits an application for candidacy to the M.S. degree,

no later than the third quarter in residence. It consists

of a Chair, who is the major professor of the candidate,

and two additional members, one of whom must also

be a member of the GGG. Suggestions for the

membership of the committee may be made by the

guiding committee, but the Advising Committee of the

GGG will have final responsibility for appointing the

committee. The thesis committee will meet with the

candidate to follow the progress of the thesis research

as needed.

After providing each member of the committee with a

copy of the thesis at least two weeks in advance, the

candidate will defend the thesis at a meeting of the

thesis committee. After the thesis is approved and

filed with the Graduate Division, a signed copy must be

sent to the GGG office.

Comprehensive Examination

The comprehensive examination committee is

appointed after the student submits an application for

candidacy to the M.S. degree, no later than the third

quarter in residence. It consists of a Chair (who must

be a member of the GGG) and two additional

members, one of whom must also be member of the

GGG. Suggestions for the membership of the

examination committee may be made by the guiding

committee, but the Advising Committee of the GGG

will have final responsibility for selecting the

committee.

The comprehensive examination will cover those areas

of General Genetics included in the course work

completed by the student. The Chair of the

comprehensive examination committee for Plan II

students shall report the results of the examination to

the GGG office and to the Dean of the Graduate

Division.

In addition to the comprehensive examination, Plan II

students will submit a 10 page scientific paper for

approval by the examining committee. The subject of

the paper will be by mutual agreement of the Chair of

the examining committee and the student.

PHD. REQUIREMENTS-

Requirements for a Ph.D. include successful completion of a Qualifying Examination, dissertation

research, and completion of a written Ph.D. dissertation.

1. The procedure for the Qualifying Examination is detailed here.

The chair of the Qualifying Examination Committee, in consultation with the student, will set the exact

date and location of the examination and provide the other members of the committee with this

information. It is the responsibility of the chair to ensure that the Graduate Division's regulations

regarding qualifying examinations are followed. When possible, the Chair will belong to the same Focus

group as the student. The role of the Chair is to 1) assure a fair examination of the student; 2) ensure a

broad examination of the major areas of genetics (particularly if the exam is also serving as the

Comprehensive Exam for a Masters degree, see below); 3) approve the topic of the alternate proposal if

required by the Focus Group.

It is the responsibility of the major professor to ensure that the student is well prepared for

examination on both the proposal and the breadth of genetics.

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33

The Qualifying Examination Committee will conduct an oral examination to evaluate the student's

knowledge of general genetics and ability to defend one or more research proposals. The aim of the

examination is 1) to determine whether the student has a broad knowledge of genetics at a level

sufficient to teach undergraduate genetics and to be able to explain genetics to the lay public, 2) to

determine whether the student understands the scientific method, particularly in the context of

genetics, 3) whether the student reviewed the literature and has the background and knowledge to

apply the scientific method specifically to the proposed dissertation project and 4) whether the

proposed dissertation project is likely to result in a significant contribution to genetic knowledge and the

timely graduation of the student.

The chair will report the decision of the committee to the Graduate Dean, and notify the student's

graduate adviser of the outcome of the examination through the GGG Administrative Assistant.

Format of Qualifying Examination

There will be a standard format for the qualifying examination for students in all Focus Groups as

specified below. Focus Groups may request a variance from the standard format. Such variances must

be reviewed by the Ed Policy Committee and approved by the Executive Committee.

The Qualifying Examination Committee will administer the oral examination at some time after April 30

in the Spring Quarter of the second year of enrollment and before March 1 in the Winter Quarter of

the third year of enrollment to determine if the student is qualified for advancement to candidacy for

the Ph.D. degree based on the criteria listed in C2b above. If circumstances are such that the qualifying

examination cannot be taken before March 1 in the third year, the student must submit a written

request with justification for a delay and proposed examination date to the Advising Committee. It is

the responsibility of the student and major professor to ensure that the qualifying exam is taken in a

timely fashion.

The examination shall include the following:

a) Presentation and defense of a written research proposal covering the proposed dissertation

research. This will be submitted to committee members not less than two weeks prior to the date

of the examination. The proposal should reflect the goal of dissertation projects to provide a

substantial and original contribution to the field of genetics. The format should be that of a Federal

grant proposal and should be no more than five pages long.

b) Oral examination covering the breadth of genetics as reflected by the subject matter of the core

courses

c) A Focus Group may require an additional research proposal, written on a subject area distinct from

the dissertation proposal, to be submitted two weeks prior to the examination and defended at the

oral examination. Alternatively, Focus Groups may require the defense of an area of genetics

distinct from the subject of the dissertation proposal.

2. Dissertation Committee

After advancement to candidacy the Dissertation Committee shall be appointed by the Dean of the

Graduate Division on recommendation of the adviser, after consultation with the major professor and

the student. Changes in membership of Dissertation Committees are made by the appointment of a new

committee and must be approved by the Graduate Division.

The major professor will serve as the chair of the committee. There will be two additional members of

the Dissertation Committee

Page 35: Genetics Graduate Group Handbook - 2007

34

The committee shall be appointed as soon as possible after the student has passed the qualifying

examination.

The Dissertation Committee shall normally include at least two members of the Graduate Group in

Genetics. The third member may have specialist knowledge pertinent to the research area and does not

necessarily have to be a member of the GGG.

The Dissertation Committee will provide the student with intellectual and technical advice on the

research project so as to allow the student to complete the research for the Ph.D. in a timely manner.

It should be comprised of faculty that are capable of providing such specialized advice.

The major professor will call for a meeting of the Dissertation Committee no more than six months

after its appointment to review the status of the student's research.

Additional meetings should be held once each year and may be held more frequently at the request of

the major professor, other members of the committee, or the student. A thesis committee report

signed by all members of the thesis committee must be completed annually for the student to be

considered as making adequate progress towards completion of their degree.

Students are encouraged to consult with all members of the committee with respect to his/her

research.

The major professor, if absent for more than two months, should so inform the student’s adviser, and

recommend a substitute to serve in his/her absence. If absent beyond the completion of the student's

research, the major professor, in consultation with the adviser, the other members of the committee,

and the student, should make all necessary arrangements for completion of the research and review of

the dissertation.

The committee shall evaluate the merits of the dissertation. The dissertation will be judged as

satisfactory on three criteria: 1) The demonstration of an in depth understanding of the specific area of

research. 2) The demonstration of the application of the scientific method in a genetic context. 3) The

generation and interpretation of data that represent significant and novel contributions to knowledge.

3. Format and presentation of Dissertation

Students will submit a dissertation based upon original research completed as a graduate student to

their Dissertation Committee for approval at least four weeks before the student wishes to submit the

approved thesis to the Graduate Division. The committee should review the thesis within four weeks

of receipt and provide the students with written comments. Prior to final approval the Dissertation

Committee should meet with the student and reach a consensus regarding the thesis based on the

criteria listed above in section IID2f.

At some time during their final six months, and before the dissertation can be signed, students must

present their dissertation research in a public seminar which shall be advertised to the membership of

the GGG.

Page 36: Genetics Graduate Group Handbook - 2007

35

PLANT BREEDING & BIODIVERSITY FOCUS GROUP

OBJECTIVES

The Plant Breeding & Biodiversity (PB&B) focus group within the Genetics Graduate Group

(GGG) will bring together faculty who are active in plant breeding and biodiversity research to enhance

the training opportunities for interested graduate students.

Plant Breeding is defined broadly as the application of genetics principles to plant improvement

for human-designated use. Research in plant breeding may involve primarily classical breeding and

genetics methodologies, or integrate them with modern molecular and genomic techniques, to

accomplish crop improvement and/or further the utilization and development of germplasm resources.

Research interests by members of this focus group span topic areas such as varietal development,

germplasm resource development and maintenance, genetic/germplasm diversity, breeding methodology

development, quantitative and qualitative trait inheritance and expression, linkage and QTL mapping,

marker-assisted selection, bioinformatics, and gene introgression from wild species through sexual or

transgenic means.

The study of Biodiversity seeks to understand the evolutionary causes of patterns of genetic

diversity. In turn, this information allows us to better maintain existing diversity, protect threatened

populations or species, and utilize it for the purpose of Plant Breeding. Biodiversity studies have

benefited significantly from the analysis of DNA and protein sequences to understand past demographic

events (such as episodes of sharp increases or decreases in population size), ecological occurrences

(such as episodes of selection), the molecular basis of phenotypic variation, and particularly adaptation.

ACTIVITIES

The PB&B focus group will:

provide visibility for recruiting students interested in this area,

develop and maintain a web page focused on the group with links to lab home pages,

facilitate and coordinate training in PB&B,

set the specialist curricula as described below (and to be developed),

organize and facilitate a GGG student-participatory seminar once every two years focused on

PB&B,

organize a GGG invited speaker seminar once every two years focused on PB&B,

assist in the function and administration of the GGG by providing representatives to serve on

GGG standing committees,

conduct a monthly journal club focused on PB&B,

provide a framework for training grants.

ADMINISTRATION

The PB&B focus group will be administered by a group leader in consultation with the focus

groups members. Recruiting, advising, curriculum development, etc. for this focus group will be the

responsibility of designated focus group members, and these efforts will be coordinated with GGG

standing committees. Focus group policy will be decided by the focus group members. Regular

meetings of the focus group will be the responsibility of the group leader.

ELECTION OF FOCUS GROUP LEADER

The focus group members will elect a Leader and by an e-mail ballot, and a simple majority of

those voting will decide the leadership. The Leader will usually serve a term of at least two years.

Service as Leader will rotate among all group members. A majority vote of the membership can request

an earlier election.

Page 37: Genetics Graduate Group Handbook - 2007

36

MEMBERSHIP

Membership is open to anyone who wishes to actively participate in the PB&B focus group for

the first year. The membership will self assess itself according to the criteria below at the end of the

first year. Thereafter, membership will be reviewed every three years by all focus group members. A

majority of the votes cast by the other group members will be required for continued membership.

CRITERIA FOR MEMBERSHIP

Maintenance of an active research program in the area of plant breeding and biodiversity as evidenced

by:

1) research activity as evidenced by peer-reviewed publications (including varietal or germplasm

releases) in the area of plant breeding and biodiversity.

2) adequate funding resources to support graduate students and to maintain a PB&B-related research

program.

3) Sustained activity in the PB&B focus group, as evidenced by active and regular participation in at

least one of the following:

4) representing the PB&B focus group on a GGG standing committee,

5) teaching or co-teaching a GGG core course or the PB&B focus group GGG seminar,

6) teaching a course directly relevant to the PB&B focus group curriculum,

7) serving the PB&B focus group as the leader or by conducting activities such as curriculum

development, journal club, student recruitment, student advising, etc.

STUDENT CURRICULUM

Courses:

All students will take the core courses and other courses required of all GGG students. In

addition, students will take at least two courses from the list A for specialization and at least one course

from list B to provide a depth of education in PB&B. These courses will be taken for a grade. Students

will also take the PB&B focus group-sponsored seminar, plus one other, in addition to GGG291. All

students will be required to TA a genetics or plant breeding-related course and will be encouraged to

enroll in GGG300 prior to advancing to candidacy.

Rotations:

In-coming students will be introduced to the breath of research of PB&B members by lab

rotations and PB&B faculty research presentations during fall quarter. In-coming students will be

required to rotate through at least two labs during their first two quarters to expose new students to

the research of PB&B members. Rotations will be coordinated by the focus group.

Qualifying Examinations:

The format of the qualifying examinations will be of a single research proposal plus a specific

defense of each of the four areas covered by the core courses with a particular emphasis on breeding.

At least one member of the exam committee will be from the PB&B focus group. The research

proposal will focus on, or be directly relevant related to, plant breeding, genetics, and biodiversity

analysis.

REVISION OF OPERATING PROCEDURES:

These operating procedures may be revised at anytime by a majority vote of the membership

and subject to ratification by the GGG executive committee.

ORIGINATING FACULTY

Paul Gepts

Dina St. Clair

David Neale

Jorge Dubcovsky

Page 38: Genetics Graduate Group Handbook - 2007

37

Course list for Plant Breeding and Biodiversity focus group: List A: depth; List B: breadth

Substitution of a course of the course list can be made with approval of the guiding committee.

List Number Title Instructor Units Quarter

Statistics & bioinformatics

A AGR205 Experimental design &

analysis

Dubcovsky 4 Winter, every year

A AGR206 Multivariate systems &

modeling

Laca 4 Spring, every year

Biodiversity

A ECL207 Plant population biology Rice 3 Winter, alternate

year

B ECL216 Ecology and agriculture Jackson 3 Fall, every year

B ECL222 Human ecology of

agriculture

Brush 4 Fall, alternate years

B EVE210 Molecular phylogenetic

analysis

Nadler, Sanderson 3 Spring, alternate

years

B EVE211 Applied phylogenetics Sanderson, Shagger,

Wainwright

3 Spring, every year

Population and quantitative genetics

A EVE102 Population and

quantitative genetics

Langley 4 Check with

instructor

Breeding

A PLB154 Introduction to plant

breeding

St. Clair 4 Winter, every year

A GGG220 Genomics &

biotechnology of plant

improvement

Michelmore 3 Winter, alternate

years

A AGR221 Advanced plant

breeding

Teuber 4 Spring, alternate

year

Plant molecular biology, development, and physiology

B PBI210 Plant ecophysiology Pearcy 3 Winter, alternate

years

B PBI220 Plant developmental

biology

Bowman, Sinha 4 Alternate years

B PBI227 Plant molecular biology Britt, Sinha 4 Winter, alternate

years

B PBI229 Molecular biology of

plant reproduction

O’Neill 3 Alternate years

B SSC208 Soil-plant

interrelationships

Richards 3 Winter, alternate

years

Plant pathology

B PLP210 Biochemistry and

molecular biology of

plant-microbe

interactions

Gilchrist, Bostock 4 Fall, alternate years

B PLP215X Genetics and molecular

biology of plant

pathogens

X 4 Winter, alternate

years

Entomology

B ENT123 Plant-Virus-Vector

Interactions

Lucas, Gilbertson, Ullman 3 Fall, alternate years

Page 39: Genetics Graduate Group Handbook - 2007

38

Requirements For PhD in Genetics

General Genetics Animal

Genetics Chromosome

Biology Human

Genetics Genetics of

Model Plants Plant Breeding

and Biodiversity

GGG Group Requirements

Core Courses

201A (5 units Fall) X X X X X X

201B (5 units Fall) X X X X X X

201C (4 units Spring) X X X X X X

201D (5 units Winter) X X X X X X

Seminars

GGG291 History of Genetics (Winter)

X X X X X X

TA Requirement X, encouraged to enroll in GGG 300

X, encouraged to enroll in GGG

300

X, encouraged to enroll in GGG

300

X, encouraged to enroll in GGG

300

X, encouraged to enroll in GGG

300

X, encouraged to enroll in GGG 300

GGG Focus Group Requirements

Specific Elective Courses

GGG211 Concepts in Human Genetics and Genomics

X

MIC263 Protein: Nucleic Acids or MIC276 Adv. Concepts in DNA Metab.

X

Additional Elective Courses 3 courses total, 1 at graduate level

for breadth

3: 2 from AG list, 3rd graduate

level for breadth

1 graduate level for breath

2: from HG approved list

3 courses: 2 from GMP approved

list, 1 with computational

emphasis, 1, with molecular

emphasis, 1 graduate level for

breath

3: 2 from list A, 1 from list B, 1

graduate level

all require adviser

approval 3rd requires

adviser approval approved by

advisor

3rd requires adviser approval

Page 40: Genetics Graduate Group Handbook - 2007

39

Requirements For PhD in Genetics

General Genetics Animal Genetics Chromosome

Biology Human

Genetics Genetics of

Model Plants Plant Breeding

and Biodiversity

Focus Group Required Seminars

GGG293 Seminar in Animal Genetics- Spring

X

GGG294 Seminar in Human Genetics- Winter

X

GGG295 Seminar in Molecular Genetics- Fall

X

GGG297 Seminar in Plant Genetics- Winter

X

GGG297 Seminar in Plant Genetics by plant breeding and biodiversity- TBA

X

MCI275 Seminar in DNA Repair and Recom

X- every quarter

except when GGG295 offered

Additional Elective Seminars

1 GGG29X Seminar + at least

1 additional seminar

at least 1 additional seminar

at least 2, at least one with

focus on human

genetics

at least 1 additional seminar

at least 1 additional seminar

Rotations Strongly

Encouraged not required, can

be arranged required- in 4 different labs

strongly encouraged

strongly encouraged

required- at least 2 different labs over 2

quarters- fall and winter

Page 41: Genetics Graduate Group Handbook - 2007

40

Requirements For PhD in Genetics

General Genetics Animal Genetics Chromosome

Biology Human

Genetics Genetics of

Model Plants Plant Breeding

and Biodiversity

Qualifying Examination Requirements (Please read additional documents for details)

Defense of dissertation

proposal and examination of core

course material

Same as for General Genetics

Same as for General Genetics, plus defense of an

alternate proposal. The Chair and

preferably two other members of the

committee will be members of Chrom Bio FG, at least one of whome must have agreed to serve on

dissertation committee of the

student

Same as General Genetics

Same as General Genetics

Same as General Genetics with emphasis on

breeding. One member from

PB&B membership

Note: All courses taken to fulfill degree requirements must be taken for a letter grade.

This includes those satisfying the seminar requirements when available for a letter grade.

Page 42: Genetics Graduate Group Handbook - 2007

41

Genetics Graduate Group Advisers 2007-2008

Adviser

Email Phone Focus Group (in addition to General)

Anne Britt [email protected] 2-0699 Chromosome Biology, Model Plants

Mary Delany [email protected] 4-9343 Animal Genomics

Holly Ernest [email protected] 4-8245 Animal Genomics

David Gilchrist [email protected] 2-6614 Plant Pathology

Nobuko Hagiwara [email protected] 2-0389 Human Genetics

Ken Kaplan [email protected] 4-5044 Chromosome Biology

Janine LaSalle (Master) [email protected] 4-7598 Human Genetics, Chromosome Biology

Bernie May [email protected] 4-8123 Animal Genomics

Maria Mudryj [email protected] 4-6090 Human Genetics

Kathryn Radke [email protected] 2-9025 Animal Science

Andy Walker [email protected] 2-0902 Plant Breeding and Biodiversity