FILE COPY.

ecor U. 5. DEPARTM ENT OF

H E AL.TH . EDUCATION. AND W ELFARE

Shannon Welcomes Experts Seeking To Improve Drugs

The science that uses animals to study drugs and relates the find­ings to man will undergo a thor­ough scientific examination at an international Symposium on Com­parative Pharmacology in Wash­ington, O.C., Jan. 24-27, at the Shoreham Hotel.

Approximately 550 expert s from the scientific community, the phar­maceutical industry, and the Fed­eral Government will attend the 4 days of scientific discussions on how to improve the safety and ef­fectiveness of drugs.

36 Papers Presented

The symposium is sponsored by the National Institute of General Medical Sciences, the National Cancer Institute, and the National Heart Institute.

Thirty-six scientific papers to b~ present ed at the symposium will run the gamut from lower marine life to man in examining how drugs are metabolized and in discussing t heir effects and interactions in various biological systems.

The svmpnsi11m's ma.ior objective (See DRUG IMPROVEMENT, !'aye 8)

J anua ry 24 1967 Vol. XIX, No. 2

Drill Invented by Dr. Robert J. Nelsen, Now on NIDR Staff, Makes 'History'

The laboratory and study o f Dr. Edward H. Angle, who firs! emphasized orthodontics in Americo in the early 1900's . W indow to his bock yard, simu­la ted in this muse um reconstruction, showed a pleasant view such as many at NIH enjoy todoy.-Smithsonian phota .

By .Jim Rice The pace of scie ntific research is so accelerated in our time that

"history" may be an event only a few years old. Such an event--the de,•elopment in 1953 of the first practical, water­

driven turbine dental drill by an inventor now on the staff of the Na­tional Institute of Dental Re-search- is reco!'ded in the History of Dentistry exhibit recently dedi­cated at the Smithsonian Institu­tion's new Hall of Medical Sciences.

Far from being a venerable old

Color Film by PHS Designed to Protect Laboratory Workers Against Infection

man, the NTDR in­vestigat or, Dr . Robert J. Nelsen (father of 6) is busy sup~rv,smg development of other innovations for dentistry,

A 35-minute movie in color, " Laboratory Design for l\Iicrobiological Safety," has been released by the Public Health Service for use by indi­viduals and groups interested in the problem of protecting laboratory workers studying highly infectious materials.

The idea for the 16 mm film came from the National Cancer Institute, where concern has been high fo1 the safety of scientists engaging in rapidly expanding studies of the Institute's Special Virus-Leukemia Program. Engineering Emphasized

Engineering principles involved in the design and construction of buildings which can safely house microbiological research are high­lighted, and the concept of p1;mar-y and seeondar y barriers in the con­tainment of microorganisms is stress"d in the film.

Personnel and equipment in lab­oratories of 9 Federal and non­government institutions are fea-

tured. Dr. Arnold G. Wedum, Chief, Industl'ial Health and Safe­ty Office, Fort Detrick, Md., na1·­rated the scr ipt which was co-au­thored by D i·. G. Rrigl{S Phillips, PHS representative to t he Nationa l Aeronautics and Space Adminis­tration; Robert Runkle, R iohaz­ards and Cont ainment Section, NCI, and Derwood R. Thayer, Au­diovisual Branch, PHS Communi­cable Disease Center.

The film (CDC Number M-1091) is avai lable on loan from the Com­municable Dis.ease Center Lib,·arv, Atlanta, Ga., and the Biohazards

(Sec COLOR FILM, /'age 4)

Dr. Nelsen is Chief of NIDR's Collaborative Re-

Dr. Nelsen search Office and its Bio-materials and Special F ield Projects.

At present, one of the special projects of this office focuses on attempts to develop a tenacious dental adhesive that wo\lld firmly bond fillings t o teeth. Forms of marine life are being stuclied in this resca-rch. (Sec N IH Record, Oct. 4, 1966.)

The turbine drill, developed at the National Bureau of Standat·ds by Dr. Nelsen and his colleagues whi le he was a 1·eseai-ch associate of the American Dental Associa­tion, has been acclaimed as one of the most significant advances h

(Seo DRnr,, l'auc 6)

NATIONAL INSTITUTES OF HEAL.TH

PUBLIC H E A L TH SERVICE

John E. Fogarty, Health Crusader, Dies at Age 5 3

Rep. J ohn Rdward Fogarty of f'.hcde lsland died in his office Jan. JO :ct the age of 53, a pparently of a m•ssive heart attack.

His cle3th occuri·ed j ust before the convening of the 90th Cong·1 ess in which he would have been swol'n in for his 14t h term.

It had become virtually accepted that what Mr. Fogarty wanted in the field of public health legislation Congress granted.

From private health and many other crganizations he won well over 100 awards.

Modesty Becomes Him

Mr. Fogarty laid b ricks in Rhode l sla,1d before coming to Congress 2() years ago. But in the Congres­sio;rnJ Di1 ectory, where he could say what he pleased, he only said of himself that he was "a Demo­crat, of Harmony, R.I., elected in l!:>40; re-el€cted to succeeding Con-1rresses."

His modesty was exceeded only by his abilities.

As soon as word of Mr . Fogar­(S-, flJ-:AI,'/'H CI/USAUfa:I{, l '«P• ,;)

Remodeling of CC Cafeteria Necessitates Inconveniences

Remodeling of the CC cafe­teria has led to inconveniences for patrons and a serious re­duction in revenue. In addi­tion, unfortunately, it has be­come necessary to reduce cafe­teria services.

Effective Feb. 13, only cer­tain menu items will be avai l­able. For breakfast: cold ce­rea l, fru it, sweet rolls, coffee and beverages. For lunch and supper: hot soup, choice of sandwiches, salads, desserts and beverages.

CC Director, Dr. Jack Ma­sur, regrets this inconvenience to staff and vis itors. Tl:e new cafeteria is expected to open in April or May.

Page 2 January 24, 1967

ecord Puhli~hcd hi-weekly at Bethesda , Md., by the Public Information Set."tion, Office of Resean·h Information, for the information of employees of the National Inst itutes of Health, principal r esearch center of t he Public Health Ser \'ice, U.S. Department of Health, Education, and Welfare. and c-irculated by r equest to all news media and inter ested members of the medical- and science-related fields. The NIH Record content is reprint­able wit hout permission and its pictures are available on request. NIH Record Office .............................. Bldg. 31, Rm. 4B13. Phone: 49-62125

Editor . .. .. ..... . ... .. .... .. ... ... . . ... . . .. .... .. .. .... . .... . . ......... E. Kenneth Stabler Stoff Correspondents

Tony Anastasi, DRS; Linda Kieffer, NCI; Bowen Hosford, CC; Mary Anne Gates, NIAMD; Marie Norris, NIDR; Art McIntire, NI MH; Bari Attis, NJNDB; George Brngaw, NHI; Faye Peterson, DBS; Wanda Warddell, NIGMS; Beverly Warran, DRFR; Dick Turlington, DRG; Martha Mader, NIAID; Loretta Navarroli, OAM; Dan Rogers, NICI-ID.

The NIH Record reserves the right to make corrections, changes or deletions in submitted copy in conformity with the policy of the paper and the Department of Health, Education, and Welfare.

lVEWSfrom PERSONNEL

BETTER COMMUNICATIONS When President Johnson lost pa­

t ience recently with fuzzy Govern­ment writing, he was not alone ;n his discontent. At NIH, employcs we-,·e a lready becoming aware of the problem through the communi­cations programs being developed by Personnel Management Ilranth.

Now the pace has speedPd np. Since last January, as one regpm~se to t he President's appeal for br,ttcr writing, two additional c0m•s1,s have been bringing special i·:ed training to the NIH staff.

One is Effective Writing:, a :w­hour defense of the English bn­guage against faulty structural patterns and excessive jargon. The other is Report Writing, also :30 hours, and a new approach to co­herence and organization on all levels of extended formal prose.

Course Is Flex ible Geared to a variety of NJ H con­

cepts, it is flexible enough to ap­peal directly to the needs of any writer, whether of research, t echni­cal, 01· prog-ram reports. Both courses are conducted by the Com­munications Skills Company of Huntsville, Ala.

This expanding emphasis on the communications skills has already attracted ovm· 200 NIH employes. They come from a g1·eat many writing and editorial positions and apply themselves ·with enthusiasm and skill. They are growing stead­ily in numbers. All this is definite proof that NJH staff members, with so much to communicate, intend to be sure that they communicate it well.

As many NIH personnel know, courses in both Effective Writing and RepoTt Writing are currently

being conducted on the reservation. Another section of each will begin on ,Jan. 30. It will meet 2 hours a day for 15 days. Additional courses will be offered later this year. In­terested persons should consult their supervisors or Institute/ Div!­sion Personnel Officer. FEDERAL WORKER LAWS

'fhe 89th Congress passed a score of laws affecting Federal employes. F ollowing is a brief summary of the principal new personnel laws :

Claims. A 6-year statute of lim­itation was established on court suits by the government to ~·ecover money erroneously paid to civilian employes or members of the uni­formed services of the United States.

Employe Compensation. The latest Federal Employe Compensa­tion Ad provides: (a) a ceiling of 75% of the monthly pay of the top step of GS-15 and a floor of 75% of the beginning step of GS-2 for monthly compensation; (b) contin­uation of benefits for educational purposes to unmarried children afte·r age of 18 up to 23, or until they complete 4 year s' education beyond high school, whichever oc­curs first; (c) $300 per mon~h when full-time attendants are re­quired; (d) a 24-month lump sum payment in lieu of continued com­pensation to a widow or dependent widower upon remarriage; (e) automatic cost-of-living increases whenever the Consumer Price In­dex has equa led a rise of at least 3% for three consecutive months over the p1·ice index of the most re­cent base month.

H ea,lth Benefits. The maximum age limit for health benefits cov­erage of an employe's eligible chil • dren was extended from 21 to 2~. And the government's contribution toward the cost of employe health insurance was inc•reased by a maxi­mum of 38c bi-weekly for a sell­only enrollment and by !l8c bi-

Tax Information, Some Help Available Beginning Feb. 1

Tax information and limited assistance in prepa1;ng tax returns will be provided in the Clinical Center and in Bldg. 31, begin ning Feb. 1. Tax forms will be available in the Institute/Division personnel offices on that date also.

Specifics on the room num­bers and 'hours of service will appear on bulletin boards and in the Feb. 7 issue of the Record.

Individuals should collect receipted medical bills, tax re­ceipts and proof of contribu­tions and prepare a draft tax return prior to seeking assist­ance.

Film on Lung Disorders Shown to NIAID Staff

A new film on chronic bronchitis and emphysema was shown Jan. 12 for staff members of the National Institute of Allergy and Infectious Diseases.

The 53-minute color movie, pro­duced by the PHS Audiovisual Fa­cility in cooperation with tlhe In­stitute of Physical Medicine and Rehabilitation of New York Uni­versity, demonstrated the latest techniques fo,· the rehabilitation of patients with advanced chronic bronchitis and pulmonary emphy­sema.

These disorders are among the lung-crippling conditions currently under intensive study by NIAID scientists and grantees. The Insti­tute recently intensified t he re­search attack with an $845,000 program of grants to scientists at 10 major medical centers.

weekly for self and family enroll­ment.

Pay. A 2.9 % pay increase be­came effective the first pay period in July 1966.

Overtime. The highest rate upon which compensation for overtime is to be calculated was changed from the minimum rate of GS-9 t ,1 the minimum rate of GS-10. Alsn, the maximum rate of GS-10 is the level above which an agency head can, at his option, elect to grant compensatory t ime instead of pay­ing overtime.

V eterans. Preference was ex­tended to honorably separated ex­servicemen and women who havt: had more than 180 consecutive davs of active duty in the ar med forC'~s since Jan. 31, 1955.

Retfrement. Optional retirement on full annuity is permitted at age 55 with 30 years' service and at age 60 with 20 years' service.

"Show me a man who makes no m istakes and I will show you a man who doesn't do things."-Theodor e Roosevelt.

THE NIH RECORD

R&W Chooses Officers; Schultheis Is Reelected

Robert L. Sohultheis, Assistant Chief of Personnel Management, Office of Administrative Manage­ment, Office of the Director, has been reelected President of the N IH Recreation and Welfare As­socia tion Board of Directors.

Also reelected t-0 the Board were Treasurer Bob Colligan, OAM, OD, and Secretary Ron Wylie, Division of Biologics Standards.

Calvin Baldwin, National Insti­t ute of Child Health and Human Development, and Hugh Connolly, Division of Research Services, were elected 1st Vice-President and 2nd Vice-President, respectively.

At a meeting held J an. 18 two additional members of the R&W executive council- comprised of representatives from each Institute and Division- were also elected to the Board of Directors.

Newly e lected R&W Officers ore, from left: Ron Wylie, Secretory; Colvin Baldwin, 1st Vice-President; Robert L. Schultheis, President; Hugh Co 11• no lly, 2nd Vice-President, and Bo!, Colligan, Treasurer. At right is H. B. Hopkins, R&W Ge neral Manager.

Blood Bank at CC Receives 164 Units in December as 11 Join 'Gallon Donor Club'

The Clinical Cent-er Blood Bank r eports that 164 units of blood were received from NIH donors in December. During the same period CC patients reecived 1,239 units of blood.

Ten NIH staff members joined the "gallon donor club." They are Louis Bender .Tr., DRS; Frederick J . Brown, NIDR; Samuel W. Copeland, NCI ; Donald F . Cyphers, NIAID; J ohn C. Eberhart, NIMH; Nathaniel H. Green­berg, NCI; Felicia J. Owens, NINDR; Robert. Reinhart, NIAID; Harold R. Sadler, NCI ; and Jan K. Steusing, N JNDB .

In addition, Chandler J . Stalvey, NLM, a regular donor at the CC Blood Bank, 1·eaehed the "gallon donor" mark.

THE NIH RECORD

1st RML Bldg. Is Made Into Museum-Memorial Honoring Dr. Ricketts

An old schoolhouse on the Bit ter ­root River in Montana, which pro . vided one of the fir st working spaces for NIAID's Rocky Moun-• tain Laboratory, will soon become a museum depicting t he labora­tor y's early achievements.

Canyon Creek School is about a mile west of Hamilton, Mont., where the Rocky Mountain Labora-

Canyon Creek School, partially re­stored, which is la be turned into 11

museum de pictin9 the early work nf the Rocky Mountain Laboratory of the NIAID at Hamilton , Mont.

tory, now an arm of the Nati~n~l Institute of Allergy and Infectious Diseases, occupies its present re­search building.

From 1922, until the present lab­oratory was occupied in 1928, the school was the site of much of the pioneering work conducted by RML scient ists on Rocky Mountain spotted fever and tick-borne tula­remia.

Jt was here that a vaccine for spotted fever was developed ancl first used. It was here that some of the first studies were made of tick-borne tularemia as a disease of man, and domestic and wi!d animals.

Renovation Underway

The Canyon Greek building has been bought by Dr. William L. Jel­lison, a retired RML scientist. He has now begun the renovation necessary to make the building into a public museum where the eady history of research at RML will be depicted.

A number of Hamilton and Mon­tana individuals and civic groups, .-tlong with the Zoology Departme,:t of the University of Montana, have already offered to assist Dr. J elli­son · in developing the museum, a project which will cost about $25,000. Income from tourists is expected to sustain the museum after it opens.

It is planned to make the mu­seum a memorial to Dr. Howa.rd 'I'. Ricketts, who worked at the labo­ratory shortly after the t urn of the century. Dr. Ricketts macle some of the early significant con­tributions to the study of Rock_v Mountain spotted fever, including

Januar y 24, 1967 Pa ge 3

NHI to Unveil Exhibit on Circulation of_ Blood at San Francisco Meeting

A newly completed NHI exhibit contrast s th.e Galen theory of blood circulation with t he "modern" Harvey concept and describes arti­ficial aids which give today's car­diac surgeons a new armamentar­ium of spare parts for the heart and blood vessels.

A large center panel exhibits patch graft s for sealing congenital heart defects or surgical incisions in blood vessels.

Synthetic textile tubes for re­placing or bypassing severely dis­eased blood-vessel segments are a lso shown a long with artificial leaflets and valves for restoring or replacing those damaged by rheu­matic fever.

Blood Pumps Exhibited

Blood pumps designed to provide circulatory assistance to failing hearts and prototypes of several total replacement devices are a lso exhibited.

The new exhibit, entitled "The Heart and Circulation" was pro­duced by the Exhibits Section of the Heart Information Center.

I t will be exhibited at the Amer­ican Academy of General Practioe meeting in San Francisco in April.

Capital University Concert Scheduled Saturday at CC The Men's Glee Club of the

Capital Universi ty, Columbus, Ohio, under the di1,ection of Wilbur E. Crist, will present a concert for Clinical Center patients on Sat., J an . 28, at 7 :30 p.m. in the CC audito­rium.

NIH employes, their fami­lies and friends are i nvited to attend, but patients will have priority in seating. Arrange­me nts for this concert were made by the CC Patient Activ­ity Section.

conclusive evidence of a tick vector and findings which later led to con­trol measures.

He went t o Mexico to study typhus fever in 1909, believing there was a connection between that diseagc and spotted fever. ln his labo,ratory there, scientists found a microorganism in the bloc><l of both typhus patients and lice; it i,-; now assumed they actually ia;,1w

the agent of typhus. Dr. Ricketts died of typhu~

fever, contracted during his re­search in 1910. Among the many posthumous honors accorded him was giving the name Rickettsia to the group of organisms which cause spotted fever, typhus, and r elated diseases. The specific or­ganism of spotted fever is called Rickettsia rickettsii.

Special Interests of Noted Sculptress Culminate in Program of Art Therapy

Hanna Y. Kwiatkowsko, Head of the Art Therapy Program of the Adult Psychiatry Branch of the Notional Institute of Mental Health, is shown dur­ing one of he r recent illustrated lectures in Brazil on psychoanalytica lly orientated family art therapy. On a Fulbright travel 9rant, Mrs. Kwiatkowsko lectured 5 weeks at the Institute of Psychiatry ot the Pontifical Catholic Uni­versity of Rio de Jane iro and a week at the Institute of Psychiatry of the Catholic Unive rsity of San Paulo.

By Michaela Richardson A woman with almost as many talents as letters in her name is Ham1a

Yaxa Kwiatkowska, Head of the Art Therapy Program of the Adult Psychiatry Branch of the National Institute of Mental Healt h.

A visiting Fulbright professor, she is also an internat ionally known sculptress, linguist, author­ess, lecturer and art therapist.

Art therapy, and mo,·e recently family art therapy, claim most of her time. According to Mrs. Kwiat­kowska, the term "family art t her­apy" is closely linked with t he de­velopment of a new trend in psy­ch iatric research- the study of t he fam ilv as a unit in the search for the g~nesis of mental illness.

Art therapy is the culmination of Mrs. Kwiatkowska's two special interests-art and psychiatry.

Uses Art As Therapy

A sculptress whose work has been exhibited on three continents, Mrs. Kv.iatkowska fi rst became in­tet,estcd in art therapy while teaching art when she noted that her students often expressed, through art, personality disturb­ances that they were unable to verbalize.

Intrigued by the possibility of using art as a technique to treat psychiatric patients, Mrs. Kwiat­kowska studied psychiatry and psychoanalytic theory at the Wil­liam Alanson White Institute of Psychiatry and the New School of Social Research in New York and at the Washington (D.C.) School of Psychiatry.

She then made the transition from artist to art therapist. Since joining NIMH in 1958, Mrs. Kwiat­kowska's sculpturing has become avocation rather than vocation.

Family art therapy added a new dimension to the concept of art

therapy that M,·s. Kwiatkowska finds especially fascinating.

Dr. Lyman Wynne, Head of the NIMH Section of Family Studies and of Adult Psychiatry, indicates that the p1·emisc behind family art therapy is that families will be assisted in perceiving though their art work inte rnal alliances and conflicts which arc not readily discernible t o themselves or the therapists in verbal communica­tion.

During the art therapy session, the family is asked to work to­gether, for example, on a painting. How they work together is an im­portant indication of how they function together as a family.

Fulbright Gro ntee

Mrs. Kwiatkowska recently re­turned from a six-week teaching stint in Brazil at the Catholic Un i­versities of San Paulo and Rio de Janeiro.

There on her second Fulbright trnvel grant, Mrs. Kwiatkowska conducted classes, seminars and clinical studies on family art ther­apy. Her first Fulbright to Brazil in 1964 was the first ever awarded for art therapy.

Trips of th is nature emphasize what Mrs. Kwiatkowska finds an especially appealing aspect of fam­ily art therapy; the fact that fami­lies the world over respond very similarly to a.rt therapy i-egardless of culturnl and social differences.

(See SCULPTRf,SS. Paue 1)

Vaccination Certificate Forms for International Travel Revised Recently

A new vaccination certificate form went into use Jan . 1, 1967 for a ll vaccinations performed in the United States for international travel.

Smallpox, cholera and yellow fever vaccination certificates a l­!'eady issued remain valid until the expir ation date of the certifi­cate.

This revised edition includes cl1anges in the smallpox and yel­low fever vaccination certificates, as amended by the Eighteenth World Healt'i Assembly in May l!l65. All certificates pdnted pri01· to October 196G should be de­stroyed.

Require ments Listed T he International Certificate of

v a c c i n at i on or revaccination re~uires the physician t:, indi~at ~ that either a freeze-dri2d or liquid vacci~e, certified t, f ulfill the WoTlj H : alth Organization's rec~mme:1d­ed requirements for manufactut·~ cf the vaccine, was used. A ls.:>, t:ie rrigin and batch number of the v:tc­cine must be recorded.

The International Ce,·tificate of v ac c in at ion or revaccination against yellow fever was amended to extend the val id ity of the cer­t ifica te from 6 to JO years as of May 12, 1965.

Certificates Available

Yellow fever vaccination certifi­cates already issued are automati­cally extended to be valid for 10 years from the date of vaccination 01· ,·evaccination.

A supply of the new certificates are on sale at the Superintendent of Documents, Government Print­ing Office, Washington, D.C. 20402, at l O cents a copy 01· $5 per hun­dred.

Tavia Gordon Named to NHI Statistical Post

Tavia Gorden was recently ap­pointed senior supervisory statis­tician for field studies in geographic pathology in connection with the NHI intramural prngTam.

His un it, as part of the Riomei­rks Research Branch, NHI, deals pi-incipally with tlhe epidemiologi­cal studies of cardiovascular dis­eases now underway in Framing­ham, Mass., Puerto Rico, and Ha­waii.

Mr. Gordon returns to NIH after an absence of six years. Prior to his present appointment he was Assistant Chief of the Division of Health Examination Statis tics of the N ational Center for Health Statistics. Before tha,t he had served five years as a statistician with the Biometric Resea,rch Sec­tion, NIH.

Luck is the crossroads where preparation and opportunity meet.

Janua ry 2-i, 1967

Edna Todd Recalls NIH in 30s; Retires After 33 Years of Federal Service

This photo, taken in 1938, shows the nucle us of the NIH Public Health Methods Brc nch. Edr,a Todd is pictured in the first row, second from the right.

By Tony Anastasi The NIH assistant director played baseball on his l:.rnch hou1· in

front of "Top Cottage"; the telephone operator called employes by their first names; there were no elevators; cne had to leave the bui lding occasionally to get a breath of fresh ai1·, away from the research animals and chemical odors, and the pay was $24 a week.

This was in the 1930s wl:e:1 Ed1:a A. Todd jci:1ed the then Na­

tional Institut~ of Health.

In 1936, she started to wo, k at NIH, wl: e,1 it was lccate:l in the old Hygienic Labora­tory at 25th and E Sts., N.W., i:1 Wa~hington, D.C. In 1938 she moved

Miss Todd with NIH to the present reservation in Rethcsda.

Miss Todd, a personnel technical assistant specializing in recruit­rr.e , t and placement, retired Dzc. 30 after 33 years of F<.:deral serv­ice-30 with NTH. Sl,e has worked in NTH pe1 son nel longe1· than any other cmploye.

Recalls Early Days

"We had one building completed and one parking lot when I first started," she said. ''We used to cat lunch at 'Mrs. Feathers.' as we called it , which was the cafeteria on the top floor of Ruilding l.

"Our usual lu nch consisted of salads and sandwiches served on a board mounted on two wooden 'horses'. Occasionally, Mrs. Wi1s0·1 (donor of most of the NTH land tract) would invite us to her hourc for lunch," she said.

Background Given

"Because of overcrowded condi­tions in those ea, ly days, our en­tire personne"I 011eration- which consisted of three persons--was located with our desks in the hall­way on the second floor of Build­ing 1," she added.

Born in Washington, D.C., Miss Todd was schooled mostly in Alex-

andria, Va. She gi-ad uated from Alexandda High School, attended the Washington School for Secre­taries for one year, and had two years of Business School. She also studied psychology and E nglish at Geor11;e Washington University in 1945-46.

Storts As Clerk

Her first job, in 1924 as a clerk, paid $15 a week. In l!l28 she jump­ed to $750 a yeaL

Her first Federal service was from 1933-86, as a clerk with tl:e Departme11t of Agriculture's For­est Se,·vice. Two years after join­ing NIH, she worked for Dr. Har­old Dorn, a pioneer in smoking and cancer s tudies. She also worked for D,·. Leonard Scheele, fo rmer PHS Surgeon General.

Enters Personnel Fie ld

She sett led on personnel work in 1938, where she has faithfully per­formed a wide range of duties eve,· s ince.

Thinking back over hel· long Fed­eral career, she said, "I can't think of any outstanding a.musing anec­dotes. I guess I've been too seri­ous.11

Nobody yet has obj•ected to her "serious" record of dedicated achievements.

COLOR FILM (C011tinued f rom f>a.Q(:.' I)

and Containment Sectio:., HCl, Bethesda, Md. 20014.

Government agencies and relate:! organizations such as grante~s may purchase copies of the film f ,o-:-i the PHS Audiovisual Facility in Atlanta. Other interes:-ed groups 01· individuals snould communicate with DuArt Film Laboratories, 245 W. 55th St., New York, N .Y. 10019, in regard to purchasing copies.

THE NIH RECORD

NHI Issues New Leaflet About Varicose Veins

Varicose veins have been recog­nized as a form of disease since 500 B.C. They are widespread throughout the p::ipulation a1cd af­fect one out of every 2 women and one out of every 4 men over the age of 40.

The major factor in developing varicose veins is weakness (often hereditary) of the veir.s in the legs and/or the valves of these veins.

Other Factors Cited Other factors are ob~sity, preg­

nancy, inoreasing age and persist­ent abdominal pressure from th-~ stcmach muscles-such as that caused by heavy li-Eting , coughing and straining.

The choice of occupation may also be a factor in acquiring vari­cos<c? veins. People in occupations that require a great deal of stand­ing are more prone to acquire them than are people with sit-down jobs.

The fact that one has varicose veins docs not always have to mean discomfort. Even the worst case can be diagnosed and treated.

Pamphlet Issued Facts abnut varicose veins: its

causes, symptoms and treatment are presented in a new leaflet en­t itled "Varicose Veins- What Can Be Done About Them," issued re­cently by the National Heart Insti­tute.

The leaflet, PHS Publication No. 154, may be obtained from the Pub­lir Health Service, Department of Health, Education, and Welfare, Washington, D.C. 20201.

Multiple copies at $11.25 per 100 may be purchased from the Super­ir,tendent of Documents , Govern­ment Printing Office, Washington, D.C. 20402.

Infectious Diseases Lab Aims To Find Volunteers for the Study of the 'Common Cold'

NIAID's Laboratory of In­fectious Diseases continues to need volunte~rs with colds for its study to combat the "com­mon" cold.

Employes with colds arc tll'ged to contribute samplings of nasal secretions plus 2 blood samples, one at the start of the illness a.nd one 3 weeks later. Participants receive $2 for each blood sample.

Appointments may be made by calling Sara Kelly or Har­vey James, Ext. 65811, pref­erably within the first 3 days of infection.

If possible, employes are re­quested to schedule appoint­ments in the moming to give investigators ample time for processing.

THE NIH RECORO January 24, 1967

HEAL TH CRUSADER (Continued frcrm Pag1:. 1)

ty's death reached the White House President Johnson issued this statement:

" J ohn Fogarty was a great lead­er and an effective member of Uon­gress. I am shocked and saddened by his death. He was a major ar­chitect i n the fields of health a nd education."

Dr. ,James A. Shannon, Director of the National Institutes of Health, said:

Shannon Pro ises Fogarty

"The sudden and shocking death of Congressman John E . Fogarty is a tragic loss to the American people.

"John Fogarty was a true cham­pion of the peoples' aspirations for better health. H is inspired leadership in the creation and ex­pansion of Federal programs for health resea1·ch and r elated activi­ties will benefit untold generations t o follow.

"The state of science anrl medi­cine in th is country-acknowledged as preeminent throughout the world-is largely atkibutable to the wise and unflagging leadership of J ohn Fogarty over the past 20 years.

Loss Is World-Wide

"Thus, the Nation's-indeed the world's- loss of John Fogarty cre­ated a void that will be virtually impossible to fill."

Speaker of the House, John \.V. McCormack, called Mr. Fogarty "one of God's noblemen." They had served tog·ether in the House for 25 years.

Rep. Fogarty intenupted his Congressional service in 1944 to join the Navy. He saw active serv­ice with a Construction Battalion (Seabees) in the Pacific theatre.

Congressman John E. Fogarty inspects the annual art exhibit in lobby of the Clinical Ce ntar with Dr. Jomes A. Shannon, Director of the NIH, in May of 1961 .-Photo by Ed Hubbard.

Recovering from a heart attack 12 years ago, Mr. Fogarty became especially interested in the Na­tional Institutes of Health and health legislation. H e was known also as a skillful debater.

Frequently in recent years, he was given major credit for per­suading the House to vote addi­tional funds for NIH and other health programs that tihe Demo­cratic administrations had request­ed.

Furthered Research

The stocky, graying Mr. Fogarty was known around Washing-ton as "Mr. Public Health." His greatest effort and achievements were in furthering medical research.

He said that "Nothing happened to me as a kid that made me decide medicine must be important."

Ml'. Fogarty is survived by his wife, the former Louise Rohland, a daughter, Mary Louise, four broth­ers, William, Raymond, T. Francis and Charles F ogarty, and a sister, Margaret A. Fogarty.

He re ot NIH, Dr. Euge ne Streicher of the Lab of Psychology Section on Aging , expla ins to the late Rep. John E. Fogarty {cente r) and forme r PHS Surg. Gen. Luther 1'erry a type of m easure ment used to determine clinical composition of nerve tissue.- Phota by Jerry Hecht.

NIH Orchestra to Play The N IH Orchestra, sponsor ed

by the Recreation and Welfare As­sociation of NIH, will present its ftrst concert this season on ·wednes­day, Feb. 1, at 8:30 p.m. in t h,; Clinical Center auditorium.

The pr ogram, to be conduct ed by Mark Ellsworth, will include Rossini's overtul·e to "The Silken Ladder," Beethoven's Third Sym­phony (Eroica) and the "Class;cal'' Symphony by Prokofiev.

All NIH personnel, their familie~, friends and neighbors are invited. Admission is free.

Dietitian Director Margaret V. Vance, Chief of the CC Nutrition De:,art­ment's Food Production Service since 19S3, receives the PHS Commenda­tion Meda l from Dr. Jock Masur, Di­rector of the Clinical Center.- Photo by Tom Joy.

Dental Decay Problems Are Explored in Booklet Issued by the NIDR

Dental decay afflicts 98 percent of all Americans at some time dur­ig thei1· lives. Beginning in early childhood, soon after eruption of the primary teeth, this disease con­tinues i ts destrnctive course t h rough permanent dentition unless preventive or restorative measures are taken.

Investigations into the causes, treatment and prevention of this universal problem are summarized in a new booklet published by the Public H ealth Service.

"Research Explores Dental De­cay," p1-epared by the National Institute of Dental Research here at NIH, discusses work underway by Institute scientists and grant­supporte rl investigators in institu­tions throughout the cou'ltrv.

It points out the wide variety of factors, such as nutrition, bacteria, oral hygiene practices and hered­ity, believed to contribute to the development of this disease.

Just as dental research is a col­laborative task, the application of research findings in preventing de­cay is a partnership effort, the booklet observes. The partners in­clude basically the scientist, the dentist and the patient.

Page 5

Dr. Samuel S. Herman To Plan and Direct the DEHS Grant Program

Appointment of Dr. Samuel S. Herman as Associate Director for the Extramural Research, Division of Environmental H ealth Sciences, was announced recently by Dr. Paul Kotin, D irec­tor of the Division.

In this position Dr. Herman will plan and direct the D i v i s i o n 's grant program to support research and training in the sciences related to environmental health p1·oblems. Dr. Herman

Dr. Herman will also be respon­sible for liaison between the Divi­sion's headquarters in North Caro­lina and the Office of the Director, NIH, as well as with the individ­ual Institutes.

The NIH Division of Environ­mental Health Sciences was estab­lished Nov. 1, of last year.

Mission Described

Focusing on the biological ef­fects of substances present or in­troduced into man's environment, the Division will conduct and sup­port research to provide a scien­tific basis for control policies and technology.

Most of the Division's operations will be located in the National En­vironmental Health Center in Re­seai·ch Triangle Park, N.C. Its g1·ant operations, however, wi ll be administered by the staff here.

D1·. Herman was formerly the Deputy Associate Dil'ector of Ex­tramural Activities, National Can­ce1· Inst itute. He has been with the Public Health Service since 1950 when he was appointed a Staff Officer in the Division of Public Health Methods.

Background Given

Dr. Herman joined Nl H in 1959 as Executive Secretary of the Ra­rl iation Study Section, Divis ion of Research Grants. His other NIH posts have included Director, Rus­sian Scientific Translation Pro­gram and Head, Foreign Grants and Awards, Office of International Research.

In 1958, Dr. Herman was a mem­ber of the National H ealth Coun­cil's Board of Directors. He has been a lectu l'er in the Department of Preventive Medicine, Howard University a nd served as Associate Editor and Co-Editor of Child De­velopment Abstracts and Bibliog­raphy.

A native of Boston, Dr. Herman graduated from H arvard Univer­sity in 1940. He received tihe D.D.S. degree from Loyola University in 1944 and the M.P.H. and Ph.D. degrees from Yale University.

Page 6 January 24, 1967 THE NIH RECORD

DRILL (Ccmti11·ued from Paoo 1)

restorative dentistry. Present-day high speed drills de­

veloped from this original are used throughout the world. They per­mit increased rotary speeds, elim­inate vibration, enable the dentist to prepare t eeth more efficiently, and give increased comfort to the patient.

The History of Dentistry exhib­its at the Smithsonian consist of period rooms and display cases that well demonstrate how today's theories can become tomorrow's therapies.

The dental exhibit is pal"ticularly noteworthy because the Smithson­ian boasts one of the world's larg­est collections of dental objects. Gold toothpicks with mother-of­pearl handles and dentures made of ivory are among hundreds of items on display.

The new Hall of Medical Sci-

Dr. Horold M. Fullme r employs on e lectrophoresis scporotor in studies of o collogen e1uymc involved in gum degcneration.- Photo by Tom Joy.

ences also traces achievements in medicine and pharmacy. One of the period rooms is a full-size res­toration of a11 1890 American phar­macy. T he Smithsonian Museum of History and Technology at 12th and Constitution Ave., where t he exhibits may be seen from 9 a.m. to 4 :30 p.m.

Accelerated Demand for NH I Publications Keeps Information Staff in High Gear

Star ting in October a sudden surge in public demand for publications prepared by the Heart Information Center has called for emergency measures involving the entire information staff.

Principal it ems requested include --------------­"Hardening of the Arteries," "He- 11,149 on "The Living Pump," 8,563 mophilia'' and "EmJ)hysema." No- on "Cerebral Vascular Disease and tices of availability appeared in Strokes," and 2,995 for the "Hand­Today's Health, an American Med- book of Heart Terms." ical Association publication; the Figures for January have not Journal of the National Education been assembled yet, but indica­Association, and U.S. News and tions are that the demand has con-World Report. tinued at only a slightly lower pace.

Some 9,158 letters and postcards Most of bhe requests came from and numerous phone cal ls were re- teachers and students, but a large ceived during the past 3 months re- number also were from physicians suiting in the distribution of 57,635 who wanted copies for their pa­publications. tients; from health department

Highest demand was for 14,382 and hospital officials, nurses and pamphlets on "Emphysema," 6,066 American Heart Association con­on " Hardening of the Arteries," tacts.

He rc's Dan Bradley bringing in another batch of requests to be sorted by Judy Wadford. Bath ore members of the HIC stoff.-Photo by Lou Cook.

'Service to Scientists' Is Guideline lor The NIH Supply Management Branch

By .Margaret Suter In time of war, supply is often referred to as "the . man _behind the

man behind t he gun," Du.ring t he day-to-day fight agamst disease here at t he NIH, supply can just as properly be called t he man behind the man behind the test tube, the titrat or, the blood cell counter, the research development contract ors.

It is to the Supply Management Branch t hat the NIH investigator looks for the equipment and the materials so vital to his research. Conversely, according to Branch Chief James B. Davis, service to scientists is the guideline for every supply activity.

The dedication of the SMB in supporting NIH research is point­ed up in the cover story of tlhe Oc­tober 19G6 issue of Laboratory Management. The article, "How NIH Buys Research Equipment," describes the divel'Sified operations of the SMB, particularly the de­termination at evel·y organii;a­tional level to make this supply support service outstanding in a ll respects.

Outlays Near $20 Millian With annual expenditures of

close to $20 mill ion, laboratory equipment valued at $50 million and a current inventory of between 3,000 and 3,200 common use items undei· its control this is no small undertaking.

In overseeing this mission, Mr. Davis is assisted by Donald R. Watson, H ead of t he Procurement Section; R ichard J. Colton, Head, Research Contracts Section, and Lewis D. Brown, Head, Property and Supply Section.

At the NIH every laboratory 'in each Institute or Division has an allotment or budget to purchase equipment and supplies. When a scient ist needs an item tlhat is stocked in the Central Storeroom operated by t he Property and Sup­ply Section, he simply requisitio~s it. A catalog in which each ,tern 1s illustrated and described aids him in making his selections.

3,000 Ite ms in Stock With $600,000-more than 3,000

items-in stock at a ll times, the section has been able to achieve a 98.6 percent supply avai lability record. Programmed into the auto­mated inventory control for each item is the demand factor based on the historical experience of how often the item is requested.

The computer reports arc used not only to up-date and maintain current inventory but also to in­dicate t he most opportune time to reorder from a price point of view.

When the item needed by a sci­entist is not in stock, he next t ums to Property and Supply's Property Uti lization Section. If it is not available here, his requisition goes to Procurement for purchase.

Procurement then contacts all N IH laboratories to see if any

other scientists expect to order the same item soon. Tf so, a multiple order will be made up so as to take advantage of quantity d_iscounts.

The Procurement Section also autho1·izes selected scientists at the various institutes to make small purchases via te lephone charge or­der (TCO). This decentralization speeds delivery and reduces the cost of handling small pu rchases.

75,000 Items Available Dollat limits for TCO's range

from $50 for general supplies and equipment to $100 for chemicals to $250 for radiochemicals. I tems available from the Central S tore­rooms are not available under TCO. Over 75,000 line items were pur­chased through TCO in 1966.

The third arm of the Supply Branch is the Research Contracts Section. When an Institute or Di­vision has occasion to contract d i­rected 1·esearch to indust1·y, edu­cational institutions and research organizations, a proposal received from a qualified source is first evaluated by the technical staff of the NIH, then submitted to the Research Contracts Section for business analysis, negotiation and execution of a contt,act. Last year the Research Contracts Section ne­gotiated almost $65 million worth of conttacts, mostly in medical 1,e­

search.

Registration for Spring NIH Graduate Program Slated Jan. 27-Feb. 3

Registration for the Spring 1967 Semester of t he Graduate Program at NIH will be held Jan. 27 throug-lt Feb. 3 from 10 a.m. to 4 p.m., in­cluding Saturday in Bldg. 31, Rm. 3-B-05.

Sixty-one courses will be offer e:I in the Behavioral and Social Sci­ences, Biochemistry, Chemistry, Genetics, Languages and General Studies, Mathematics, Medicine and Physiology, Microbiology and Im­munology, Physics and Statistics.

New courses to be offer ed in the spring semester are New Spectro­scopic Methods and their Applica­tions, Medicinal Chemistr y, Ultra­struct ural Aspects of Cell Biology, Immunohematology and BI o o d Transfusion, Statistics for Mana­gerial Decisions, and Time Ser ies Analysis.

Textbooks for the courses may be purchased in Bldg. 31, Rm. 3-B-05 from 9 a.m. to 4 p.m.

For fu1:ther information on cata­logs call Ext. 66371.

THE NTH RECORD January 24, 1967 Page 7

Helen M. Reed Retires After 33 Years With Government Agencies

Helen M. Reed, Editorial Clerk of t he National Institute of Child Health and Human Development's Information Branch, reti1·cd J an. 1. Miss R~ed had been an active gov­ernment employe in a variety of Federal agencies for 33 years.

She had been with the NICIID Information s t aff ~ince July 1966. Originally coming to NICHD in 1964, Miss Reed served as an Editorial As­

Miss Reed

sistant, until last July, in the Tech­r.ical Communications Branch.

While in that position she helped edit and prepare three major con­ference proceedings published by NICHD in 1966.

Defore coming to the NI H, Miss Reed was with the Division of Den­tal Public Health and Resources Information Office (1963-64); re­gional DIIEW Office of Education, Kansas City, Mo. (1962-63), and the Post Office Department in St. J oseph, Mo., and Denver, Colo. (1946-62).

Before r eturning to her home­town, Spencer, Neb., Miss Recd was honored at a retirement lunch­eon given by the NICHD Publi,· Information Branch.

Dr. Axelrod Honored by University of Chicago

Dr. Julius Axelrod, Chief, Sec­tion on Pharmacology in t he Lab­oratory of Clinical Science in the National Institute of Mental Health, 1·eeently was awarded an honoi-ary Doctor of Science degree by the University of Chicago.

He was cited for his research i n drug metabolisn1 on the sympathet­ic nervous system an cl the pineal gland. The Uni-versity also prais- Dr. Axelrod ed h is impressive record as a teach­er of pharmacologists.

His Students Contribute

Many individuals who have studied with him, both from the Un ited States and abroad, have since made important contribu­tions in their own right, the cita­tion noted.

Most of Dr. Axelrod's research and training activities were done at the NIH.

Dr. Axelrod is the first pharma­cologist in more than 60 years and only the second ever to receive an honorary degree of the Unive,·sity of Chicago. The ffrst was Nobel P,·izcwinner Dr. Paul Ehrlich.

Dr. Axelrod joined the PHS in 1!)49 with the KHI and transferred to his present position at NI MH in 19fifi.

Preceding a tour of the Clinical Cente r, Dr. Robert M. Farrier (center), CC Associate Director, shows a model of the NIH buildings and grounds to Dr. Somine Oolo, Minister of Public Health and Social Affairs, Mali (left) and Or. Cheick Sow, Director, Endemic Disease Service, Ministry of Health, Moli. The two African officials also renewed their acquaintance with Dr. Horry M. Meyer Jr., of DBS, co-deve loper of the Germon measles vaccine, and visited Dr. John R. Seal, Scientific Director of NIAID. The United Stoles is sponsor­ing O smollpo11-erodicotion program in Moli.-Photo by Tom Joy.

'Farmer' Henry Essential Crops

lutterlough Harvests for NH/ Scientists

Henry Lutterlough with 27 yeaTS of NIH service behind him, the last 4 years with the National Heart Institute, mig ht well be introduced to a TV audience of "V.'hat's My Line" as a "Farmer for Scientists."

The master of ceremonies could t hen go on to further confuse the panel of experts by informing them that Mr. Lu ttcr-lough lives in Washing­ton, D.C., is manfod, is the father of one daughter and has two gi·and­children, and performs a service.

The panel would get a "yes" to the quest ion of whether or not "this is a useful service from which anyone can derive personal be.ne­fit," though the proviso "indi­rectly" would be added.

The 1>anel would also get a "yes" to such questions as, "Is this serv­ice perfo,·med outside the Distl"ict of Columbia" and " Is its perform­ance something that requires spe­cial skill and knowledge?"

He 'Plows No Acres'

Actually, Mr. Lutterlough plows no acres, hoes no orderly rows, nor does he wait several months for "crops" to mature. He reaps his increase almost overnight. The bac­teria he grows in 320 liter batches increase by the billions to yield a harvestable p1·oduct in from G hours to a week depending on the species.

Classified as a laboratory tech­nician, he was once the only full­time person engaged in such spe­cialized work at NIH. Now he has about al l he can do to produce enough bacteria to supply the needs of medical research scientists of the NIII. One or two other grow­ers are s imilarly employed else­where on the reservation.

His favorite crop and the one in g 1·eatest demand is Escherichia coli or E. coli, as it is more commonly known.

Bacterium Found in Mon This bacterium, normally found

in the intestinal tracts of man and other warm blooded animals, is a favorite with investigators studying enzymes, particularly the activity of enzymes in r elationship to cel­lular and body metabolism.

Tt takes about 18 hours to g row a 320 liter batch of cells. The liq­uid containing the bacteria is then drawn off, centdfuged and the bac­terial cells recovered from the cen­trifuge for use by the scientists.

During growth everything must be kept sterile o r "weeds" appear, especially when a i-ich ye,ast ex­fracl medium is used. When phos­phates and sugars are added "all kinds of 'bugs' just love it," says Mr. Lutterlough.

Lab Technician Lutterlough's laboratory-farm is so crowded with the giant tank, th1·ee huge ccmt1i fuges, car boys, refrigerators for cooling, and a maze of piping, that there is hardly room enough left for the small desk he uses to keep track of the paperwork.

The man-on-the-street frequently

forme r Lutterlough, unlike conven­tional formers, is not at the mercy of freezes, droughts, hoilstorms, and other quirks of the weather. Using the Honeywell- Brown temperoture re­corder, he exercises nearly complete control over the "climate" in which his crops grow.-Photo by Ed Hub­bard.

wonders why medical scientists are so interested in working with t he lower p lants and animals when the ills of mankind would seem much more wo1thy of direct attack.

They forget that all living things- man, mold, monster or mouse--are constructed of the same elementary molecules and follow similar paths of body me­tabolism.

Because they react to their en­vironment in ways that arC! similar it is most important to study living things in their simplest forms so that previews can be obtained of what to look for in higher, more complex organisms.

"Farmer" Luttedough can right­ly feel he has an important job to do-essential to success of the sci­entists he serves.

SCULPTRESS (Continued from Paor !I)

Art is used as an universal mode of communication in a new method of psychiatric evaluation.

Mrs. Kwiatkowska is in a par­ticularly advantageous position to interpret world-wide response. A native of Poland, she has lived in France, Switzerland, Austria, Italy, Manchuria and Brazil. She speaks Po1-tuguese, Polish, Russian, French, Italian and German as well as English.

Educated at t he Ecole des Beaux Arts in Geneva and the Academy of Fine Arts in Warsaw, Mrs. Kwiatkowska has published exten­sively in her field and is sought as guest lecttu-er by many universi­ties. She is currently pmparing an article on her work for publication in the first part of the year.

Page 8

Nichols Writes '30' to Colorful and Exciting Career in Government

Herbert Bishop Nichols, 59, As­sistant Chief for Public Informa­tion of the National Heart Insti­t ut e, ended a long and colorful Fed­eral career that spanned four dec­

ades with a sim­ple, quiet office get­togethc1·, Dec. 30 of last year.

This was as it should be, for the ta 11, grey-haired Connecticut Yan­kee is a quiet, in­trospective man whose staid manner

Mr. Nichols be)i,es an exciting career that few w1'iters in Federal Service have rivaled.

Mr. Nichols was a recol'der and communicator of natural and un­natural history. H is travels took him twice to uncharted regions of the Antarctic as an obser-vel' for Admiral Byrd and t he Secretary of the Army; to China and Burma as p ress intelligence officer to Lt. Gen. Wedemeyer while U.S. Forces in China were wresting control of t he "backdoor" to Asia from the Japanese in World War II.

Earlier still he went to Panama, where he commanded an a1iillery battery of 14 asso1ted guns guard­ing the ba~kdoor to the Canal at the mouth of the Chargrcs River.

Mr. Nichols has been a science writer since his free-lancing days as an unde1·graduate at Harvard University and as a graduate stu­dent at Roston Unive1·sity.

Positions Noted

For the next 18 yea,·s, he was :-.iatural Science Editor for the Christian Science Monitor .

In 1949 he became Spc'Cial As­sistant for P ublic Information to the Director of the U.S. Geological Survey, serving until Hl62.

While on a year's leave of ab­sence from USGS, he was asked to aid in the establishment of a pub­lic relations unit for the General Electric Research Laboratory in Schenectady, N.Y.

In 1946 he was co-winner of the George Westinghouse Award of the American Associat ion fo1· t he Advancement of Science for dis­tinguished service to science in the fi(, ld of journalism.

He is a Fellow aud Council mem­ber of the AAAS, a member and Past President of the National As­sociation of Science Writers. He is a lso a member of the Explorers Club of New Yoek, the Geological Society of Washington, Pas.t Presi­dent of 1Jhe Bond Astronomical Club at Harvard Observatory and the Ve rmont Botan ical Club. He was retired as a Lt. Col. in the U.S. A rmy 1·eserve in 1!)60.

Mr. Nichols came to NIH in

January 24, 1967

Cancer Nursing Service at CC Receives Award

CC Nursing Deportment's Cance r Nursing Service employes, who recently received o group award for high quality patient-care, ore shown here with Or. Nathaniel Be rlin and Or. Poul Carbone, both of NCI, and Eileen Jones, Asst. Chief of the Cancer Nursing Service. Seated, from left: Dr. Be rlin , Gera ldine Vernon, Head Nurse Ada Hruska and Dr. Carbone. Standing, from le ft : Mrs. Jones, Margaret Cromer, Donald Asson, Marlho Ne wsom, Marie Weaver, Juanita Broke, Mildred Woll, Linda Headrey, Irene Peyton, Joseph Murray, Agnes Keating and Dorothy Smith. Award winne rs not shown ore Potricia McIntire, Doretha Stone, Mary Brown, Patricio Gilliom, Kenneth Broxton and Mortin Stewort.-Photo by Tom Joy.

DRUG IMPROVEMENT (Conti,wcd ft·ou1 Pa-!}6 J)

is to facilitate information among a multidiscipl inary group of scien­tists. Pharmacology, toxicology, veterinary medicine, primate 1·e­search, zoology, biology, marine bi­ology, physiology, entomology, bio­chemistry, and physics ai-e among the scientific disciplines Tepresented.

Dr. James A. Shannon, Director of the National Institutes of Health, will welcome the conferees at the opening symposium session at 1 :30 p.m. today. Dr. Frederick L. Stone, Directol· of the National Institute of General Medical Sci­ences, will offer the introductory rem,1rks, and Dr. William G. Van der Kloot, Professor and Chairman cf t he Department of Physiology of New York University, will deliver the keynote address, "Go,tls and Strategy of Comparative Pharma­cology."

Exte nsive Studies Needed The symposium will emphasize

the need for extensive studies of drugs in animals before clinical testing, and later application to diseases in man. The animal studies are an integral part of national and international research efforts a imed at improving drug safety and efficiicy.

It has been customary to use nol·mal, healthy animals in such drug studies but the drugs even­tually will be administered to the sick or handicapped. Therefore,

1962 as Information Officer of the then DGMS, served two years as Information Officer of DRFR, and then joined the Heart Information Center of NHI as Assistant Infor­mation Chief in 1964.

Mr. Nichols plans to continue sci­ence writing on a free-lance basis.

many pharmacologists are inducing disease states in anima ls simi lar to those found in man and treating the animals with drugs.

Pharmacologists at the U niver­sity of Iowa, in research supported by t he NIGMS, have induced arti­ficial kidney disease, ncurogenie disease, and endocrine disorders in several species and are testing the reactions of these animals to com­m:m drugs. Such research is an im­portant step toward improving the safety and efficacy of drugs.

Drug Effects Investigated

The use of animals of simplified structure, notably such single nerve fiber marine animals as lobsters, crabs, and squid, have proved par­ticularly useful in helping scien­tists learn more about the effects of drugs on the central nervous system. Marine animals such as the squid, which excretes an ink-like substance for protection, a lso can prove extremely useful in studying how toxic materials are excreted in man and why drugs may be ex­creted more rapidly in some indi­viduals than in others.

The effects of insecticides and pesticides on marine life will be discussed by Dr . Richard Adamson of the NCL In his paper, "Drug Metabolism in Marine Vertebrates," Dr. Adamson cites marine life ex posed to industrial wastes and pes­ticides and t oxic, tumor-causii:g chemicals in fish as t wo basic rea­sons for studying the disposition of dl'ugs in marine vertebrates.

Observing metabolic processes in these forms can help determine what effects insecticides exert on marine life and what possible ef­fects such chemicals may have on human populations that consum~ large quantities of fish and seafood in t heir daily diet s.

THE NIH RECORD

Dr. Rosenthal, Noted for Schizophrenia Research, Named Lab Chief Here

Dr. David Rosenthal, noted for his research in schizophrenia, has been named to head the National Institute of Mental Health's Lab­oratory of Psychology at the Na­tional Institutes of Health.

He succeeds Dr. David Shakow, Chief of t he Laboratory for 12 ye:irs, and one of the Nat.ion's leading authorities in schizophre­ma.

At NIH Since '55

Dr. Rosenthal received his doc­torate in psychology at the Univer­sity of Chicago in 1952. He taught at J ohns Hopkins University, se1·ved at its hospital and then came to NIMH in 1955 as Research Psychologist, a post he held until his promotion Dec. 1.

Dr. Rosenthal has been widely accla imed for his series of papel'S on the problem of heredity in sch izophrenia. NIMH's 10-year study of the Genain quadruplets­the only case known Lo medicine of schizophrenic quadrnplets---which he edited has had an important im­pact in the field.

While administering the work of some 23 scientists in t he Lab-

Dr. Shakow Dr. Rosanthol oratory, Dr. Rosenthal will con­tinue his research to determine the 1·oles that both he1·edity and environment play in producing schizophrenia.

Dr. Shakow, who asked to be re­lieved of the post of laboratory chief, wil l continue his extensive research studies and writings as Senior Scientist attached to the Office of the Director of Clinical Investigations.

A recipient of numerous profes­sional awards, Dr. Shakow helped pioneer the development of clini­cal psychology in the Un ited States.

H e is wel l known for his cl inical and experimental studies which systematized tlhe diagnoses of schizophl'enia, and outlined the deficits in pernonality that differ­entiate schizophrenics from normal people.

An expert in the history of psy­chiatry and psychology in th.is country, he is the author, along with Dr. David Rapaport, of the book, "The Influence o.f Freud on American Psychology."