file copy ecor - nih record · pow~l's continues to interest the medical profession. although...

8
FILE COPY ecor U. 5. DEPARTMENT OF HEALTH. EDUCATION. AND WELFARE July 8, 1970 Vol. XXII, No. 14 Dr . Bernard B. Brodie Receives Four Honors For Studies on Drugs Notable Achievements of 35 Employees Cited at NIH Honor Awards Ceremony Dr. Bernard B. Brodie, chief of the Laboratory of Chemical Phar- macology in the National Heart and Lung I nstitute since 1950, re- ceived four honors last mon,th, Dr. Robert Q. Marston, NI H Director, p1,escnted DHEW awards to 35 employees at the Second Annual NIH Honor Awards Ceremony on Monday, June 29, in the Jack Masur Auditorium, Clinical Center. Recipients included Civil Service employees, Commissioned Officers, Dr. Brodie, a distinguished pio- m~ering pharmacologist, was hon- ored by the New York Aca.demy of Sciences, the New York Medical College, the AmericM 'I'herapeutic Society, and the American Academy of Achievement. Dedicate Confere nce A conference dedicated entirely to Dr. Brodie, sponsored by the New York Academy of Sciences, was held in New York City, J une 29- July 1. At this Conference on Drug Me- tabolism in Man, Dr. Brodie deliv- ered a paper entitled "Dt·ug Metab- olism in Man: Past, Present and Future," describing tissue damage caused by drugs and roising the strong possibility that drug-induced diseases a.re mediated by "active" derivative.~ formed in the body. Previously, it had generally been assumed that metabolites are less toxic t han the parent compound, but Dr. Brodie and his group found that (See DR. BRODIE, Page 6) staff members who had recently left NIH f.or ot her assignments, and employees who retil-ed a short time ago. Richard L. Seggel, Associate Di- 1,ector for Administration, intro- duced the award winners and read their citatio11s. The Joint Armed F orces Color Guard and the U.S. Marine Drum and Bugle Corps performed before the awards presentation. Following the cc1,emony a re- ception was held for the award re- cipients, their families, and NIH officials. In his address, Dr. l\1Iarsto11 noted that "the most precious, the most fragile, and the single most im- portant ingredient in major fields of human endeavor such as science and health is outstanding achieve- ments by talented individuals. "This is a truth that should be a part of every decision we make, and a truth that is the total rea- son for holding these ceremonies today. "As each year we publicly rec- ognize such accompli~hments, this ceremony also gives us the oppor- Sterilized Maggots Us ed to Heal Wounds May Give Insigh t Into Human Metabolism By Kati e Broberg The lowly maggot is commanding respect as evidence of its healing pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help Four stages in the metamo rphosis of o blowfly ore: bottom lef t, egg; t op le ft, larva or maggot; bottom right , pupa, ond t op right, adult blowfly. heal certain wounds, medical re- searchers are now ta.king a second look at beneficial effects. Sterilized maggots are being used to heal gangrenous wounds in a process called traumatic myiasis, 01· wound treatment by maggot infestation. Unsavory as this may seem, sci- entifically it is sound practice, ac- cording to D1·. Leo Levenbook of the Nation-al Institute of Arthritis and Metabolic Diseases. Dr. Levenbook has been raising blowflies-relative of the comm.on housefly-to exam.ine their devel- opment from maggot to ad\1lt fly. The eggs of the blowfly develop (See MAGGOTS, Pao• 8) tunity to reassert that excellence must be the hallmark-past, pres- ent, and future-of an entity such as the National Institutes of Health. If it is not, we have little to offer, but with it, all other prob- lems shrink in magnitude. The DR EW Superior Service Award, presented to Civil Service employees whose services and/or achi evements deserve special rec- ognition of a high order, was pre- sented to the following employees: Special Se rv ice Recog nized Dr. Benjamin T. Bui'fun, asso- ciate director for Program Analysis and Scientific Communications, NIAMD, "For instituting outstand- ing programs in scientific com- munications and for astute man- agement of programs supp.orting varied NIAMD missions, espeeially those in chronic kidney disease and nutrition." Carl A. Fretts, formerly special assistant for Business Adminis- tration, Chemotl1erapy, NCI, "For his superb administrative skills in substantially accelerating the de- velopment of new drugs for the control of human cancer." Dr. D. Carleton Gajdusek, su- pervisory medical officer, Collabo- t·aiive and Field Research, NI NDS, "In l'ecognition of his unique re- search in exotic cultures and his contributions to the field of slow (Conti-n1<'ld on Pa,ge ~) TV Program on July 19 Features NINOS Work Four NIH staff members will parbicipate in an HEW television program, "You and Your Nei-vous System," Stmda.y, July 19, from 2:30 to 8 p.m., on Ohannel 4, WRC- TV. Following a 10-minute film, "Ex- ploring the Human Nervous Sys- tem," issued by the National I n- stitute of Neurological Diseases and Stroke, Drs. John Sever, Ayub Orn ma ya, an.d Roscoe Brady, all of NINDS, will discuss their Insti- tute's research work, particularly NATIONAL INSTITUTES OP- HEALTH Dr. Baker Named Director of Nat'I Cancer Institute Appointment of Dr. Carl G. Baker as Director of the National Cancer Institute has been an- nounced by Dr. Robert Q. Marston, Director of NIH. Dr. Baker, a physician and bio- chemist who has been on the NCI staff si nce 1949, becomes the Insti- tute's sixth director in its 88-year history. He has been Acting Di- Dr. Boker received the PHS Meritori- ous Se rvice Medal in 1966 for de- veloping research planning systems. rector since last November. He is a graduate of the Univer- si ty of Louisville in Kentucky and received his M.D. degree from the University's School of Medicine in 1944. Dr. Baker served as a Medioof Officer with the U.S. Navy in the Paci.fie Area in Woi-ld War II, and aftei- t he war became a Childs Fel- low at the University of California at Berkeley where he 1·eceived the M.A. degree in Biochemistry in 1949. Between 1949 and 1955, Dr. Baker worked in the NCI Laboratory of Biochemistry and the Research Grants and Fellowship Branch. (See DR. BAKER, Page 7) that undertaken in t heir lnbo ro- tories. Fredrica Santell, a biomedjcaJ technician in the National Institute of Child Health and Human De- velopment, took part in the di!\cus- sion and also explained how tissue cells ro:e grown in her laboratory.

Upload: others

Post on 07-Jul-2020

4 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: FILE COPY ecor - NIH Record · pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help ... achievements deserve special

FILE COPY

ecor U. 5. DEPARTMENT OF

HEALTH. EDUCATION. AND WELFARE July 8, 1970

Vol. XXII, No. 14

Dr. Bernard B. Brodie Receives Four Honors For Studies on Drugs

Notable Achievements of 35 Employees Cited at NIH Honor Awards Ceremony

Dr. Bernard B. Brodie, chief of the Laboratory of Chemical Phar­macology in the National Heart and Lung Institute since 1950, re­ceived four honors last mon,th,

Dr. Robert Q. Marston, NIH Director, p1,escnted DHEW awards to 35 employees at the Second Annual NIH Honor Awards Ceremony on Monday, June 29, in the Jack Masur Auditorium, Clinical Center.

Recipients included Civil Service employees, Commissioned Officers,

Dr. Brodie, a distinguished pio­m~ering pharmacologist, was hon­ored by the New York Aca.demy of Sciences, the New York Medical College, the AmericM 'I'herapeutic Society, and the American Academy of Achievement.

Dedicate Conference A conference dedicated entirely

to Dr. Brodie, sponsored by the New York Academy of Sciences, was held in New York City, J une 29-July 1.

At this Conference on Drug Me­tabolism in Man, Dr. Brodie deliv­ered a paper entitled "Dt·ug Metab­olism in Man: Past, Present and Future," describing tissue damage caused by drugs and roising the strong possibility that drug-induced diseases a.re mediated by "active" derivative.~ formed in the body.

Previously, it had generally been assumed that metabolites are less toxic t han the parent compound, but Dr. Brodie and his group found that

(See DR. BRODIE, Page 6)

staff members who had recently left NIH f.or other assignments, and employees who retil-ed a short time ago.

Richard L. Seggel, Associate Di-1,ector for Administration, intro­duced the award winners and read their citatio11s.

The Joint Armed F orces Color Guard and the U.S. Marine Drum and Bugle Corps performed before the awards presentation.

Following the cc1,emony a re­ception was held for the award re­cipients, their families, and NIH officials.

In his address, Dr. l\1Iarsto11 noted that "the most precious, the most fragile, and the single most im­portant ingredient in major fields of human endeavor such as science and health is outstanding achieve­ments by talented individuals.

"This is a truth that should be a part of every decision we make, and a truth that is the total rea­son for holding these ceremonies today.

"As each year we publicly rec­ognize such accompli~hments, this ceremony also gives us the oppor-

Sterilized Maggots Used to Heal Wounds May Give Insight Into Human Metabolism

By Katie Broberg

The lowly maggot is commanding respect as evidence of its healing pow~l'S continues to interest the medical profession.

Although maggots were used briefly during both World Wars to help

Four stages in the m etamorphosis of o blowfly ore: bottom left, egg; top le ft, larva or maggot; bottom right, pupa, ond top right, adult blowfly.

heal certain wounds, medical re­searchers are now ta.king a second look at beneficial effects. Sterilized maggots are being used to heal gangrenous wounds in a process called traumatic myiasis, 01· wound treatment by maggot infestation.

Unsavory as this may seem, sci­entifically it is sound practice, ac­cording to D1·. Leo Levenbook of the Nation-al Institute of Arthritis and Metabolic Diseases.

Dr. Levenbook has been raising blowflies-relative of the comm.on housefly-to exam.ine their devel­opment from maggot to ad\1lt fly. The eggs of the blowfly develop

(See MAGGOTS, Pao• 8)

tunity to reassert that excellence must be the hallmark-past, pres­ent, and future-of an entity such as the National Institutes of Health. If it is not, we have little to offer, but with it, all other prob­lems shrink in magnitude.

The DR EW Superior Service Award, presented to Civil Service employees whose services and/or achievements deserve special rec­ognition of a high order, was pre­sented to the following employees:

Special Se rvice Recognized

Dr. Benjamin T. Bui'fun, asso­ciate director for Program Analysis and Scientific Communications, NIAMD, "For instituting outstand­ing programs in scientific com­munications and for astute man­agement of programs supp.orting varied NIAMD missions, espeeially those in chronic kidney disease and nutrition."

Carl A. Fretts, formerly special assistant for Business Adminis­tration, Chemotl1erapy, NCI, "For his superb administrative skills in substantially accelerating the de­velopment of new drugs for the control of human cancer."

Dr. D. Carleton Gajdusek, su­pervisory medical officer, Collabo­t·aiive and Field Research, NI NDS, "In l'ecognition of his unique re­search in exotic cultures and his contributions to the field of slow

(Conti-n1<'ld on Pa,ge ~)

TV Program on July 19 Features NINOS Work

Four NIH staff members will parbicipate in an HEW television program, "You and Your Nei-vous System," Stmda.y, July 19, from 2:30 to 8 p.m., on Ohannel 4, WRC­TV.

Following a 10-minute film, "Ex­ploring the Human Nervous Sys­tem," issued by the National In­stitute of Neurological Diseases and Stroke, Drs. John Sever, Ayub Orn ma ya, an.d Roscoe Brady, all of NINDS, will discuss their Insti­tute's research work, particularly

NATIONAL INSTITUTES OP- HEALTH

Dr. Baker Named Director of Nat'I Cancer Institute

Appointment of Dr. Carl G. Baker as Director of the National Cancer Institute has been an­nounced by Dr. Robert Q. Marston, Director of NIH.

Dr. Baker, a physician and bio­chemist who has been on the NCI staff since 1949, becomes the Insti­tute's sixth director in its 88-year history. He has been Acting Di-

Dr. Boker received the PHS Meritori­ous Se rvice Medal in 1966 for de­veloping research planning systems.

rector since last November. He is a graduate of the Univer­

sity of Louisville in Kentucky and received his M.D. degree from the University's School of Medicine in 1944.

Dr. Baker served as a Medioof Officer with the U.S. Navy in the Paci.fie Area in Woi-ld War II, and aftei- t he war became a Childs Fel­low at the University of California at Berkeley where he 1·eceived the M.A. degree in Biochemistry in 1949.

Between 1949 and 1955, Dr. Baker worked in the NCI Laboratory of Biochemistry and the Research Grants and Fellowship Branch.

(See DR. BAKER, Page 7)

that undertaken in t heir lnboro­tories.

Fredrica Santell, a biomedjcaJ technician in the National Institute of Child Health and Human De­velopment, took part in the di!\cus­sion and also explained how tissue cells ro:e grown in her laboratory.

Page 2: FILE COPY ecor - NIH Record · pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help ... achievements deserve special

Page 2 July 8, 1970

,m,~ _Record Published biweekly at Bethesda, Md., by the Publications and Reports Branch, Office of Information, for the information of employees of the National Institutes of Health, Department of Health, Education, and Welfare, and circulated by request to interested writers and to investi­gators in the field of biomedical and related research. The content is reprintable without permission. Pictures are available on request. The NIH Record reserves the right to make corrections, changes or dele­tions in submitted copy in conformity with the policies of the paper and the Department of Health, Education, and Welfare. NIH Record Office ............ ............ Bldg. 31 , Rm. 2B-03. Phone : 49-62125 Editor ......................... ........ ... ... .. ... .... ........ ............. ............ . Frances W. Davis Assistant Editor .............................. ... ... ....... . ..... .. .... .. .... ..... ..... ..... Fay Leviero

Stoff Correspondents ADA, Nelson Sparks; BEMT/OD, Florence Foelak; CC, Thomas Bowers; DAHM, Laura Mae Kress; DBS, Faye Peterson; DCRT, Joan Chase; DDH, Carolyn Niblett; DERF, Beverly Warran; DHMES, Art Burnett; DN, Evelyn Lazzari; DPM, Eleanor Wesolowski; DRG, Marian Oakleaf; DRR, Helene Doying; DRS, Robert Knickerbocker; FIC, Jan Logan; NCI, Pat Gorman; NEI, Julian Morris; NHLI, Anne Tisiker; NIAID, Krin Larson; NIAMD, Katie Broberg; NICHD, Lloyd Blevins; NIDR, Sue Hannon ; NIEHS, Elizabeth Y. James; NIGMS, Wanda Warddell; NIMH, Marjorie Hoagland; NINDS, Margaret Suter; NLM, Paul Kelly.

John C. Schlag (r), ODA, receives the NIH Federal Credit Union's " Surprise of the Month," on electric ice c ream maker, from Dr. Harley G. Sheffield, a member of the Board of Directors. A different gift is offered monthly­with winners selected by rondom draw­ings from active occaunts. These num­bers ore then published in the CU monthly Newsletter.

Final Report Reveals Bond Drive Increased Allotments 3.5 Percent

A 3.5 percent increase in sub­scriptions as a result of the NIH U.S. Savings Bond Drive for 1970 was reported by Dr. Seymour J. Kreshover.

Dr. Kreshover, Chairman of the drive which ended June 19, is Di­rector of the National Institute of Dental Research.

Edward B. Radden, bond canvas­ser for the Environmental Services Branch of the Division of Research Services, will receive a Minute Man citation from the Treasury Depart­ment for obtaining 100 percent par­ticipation in his branch.

"I wish to thank the individual Savings Bond Chairmen and those in the Institutes and Divisions who worked as canvassers for -their fine

Dr. George Fisher Joins Grants Asso. Program

Dr. George L. Fisher has jonied the NIH Grants Associates pro­gram for a year of specialized training in grants administration.

Dr. Fisher had been wibh the University of Maryland since 1965, first as assistant professor of psyJ chology and, since 1967, as an asso­ciate professor.

He was also associated with Brown University for 4 years as assistant professor and research associate and lecturer, and spent 3 years at Boston University as a re­search and teaching assistant.

Dr. Fisher received his B.B.A. in Industrial Psychology from the City College of New York in 1956, his M.A. in General Psychology from Boston University in 1957, and his Ph.D. in Physiological Psychol­ogy from Boston University in 1962.

He is a member of many organi­zations which foster scientific re­search in the field of psychology, including the American Psycholog­ical As!;ociation and the Society for Psychophysiological Research.

Dr. Fisher also served on the Executive Council of the Maryland Psychological Association in 196"7 and 1968.

Since 1965, Dr. Fisher has been engaged in studies of taste prefer­ences in animals and men.

and dedicated perfoirmance," Dr. K.reshover said.

"Through their efforts a total of 369 new subscribers signed up, and 279 other NIH employees increased their allotments."

Dollar amount allotted per pay period for new subseribers 1·eached ~6,040.67 at the Drive's end.

NIH Television, Radio Program Schedule

Television NIH REPORTS

WRC, Channel 4 1 a.m. Wednesday-following the J ohnny Garson Show.

July 8 Dr. Seymour Kreshover,

Director, NlDR Subject: The Role of NIDR,

Pa.rt 1 (R) July 15

Dr. Seymour K.reshover Subject: The Role of NIDR,

Part 2 (R)

Radio DISCUSSION: NIH

WGMS, AM-570- FM Stereo 103.5-Friday evenings­About 9:15 p.m.

July 10 Dr. Peter L. Frommer, chief,

Myocardial Infarction Bronch, NHL!

Subject: An Approach to Re­ducing Death and Disabil­ity .from Heai:it Attack (R)

July 17 Dr. Kiffin J. Penry, head,

Epilepsy Section, Collabo­rative and Field Rei;earch, NINDS

Subject: Inoi-dence of Epilep­sy: Its History and Con­trol (R)

Interview takes place during the progl'am, The Music Room.

R&W Membership Elects Entire Incumbent Board

A 7 to 8 percent increase in votea: turnout marked the 1970 NIil Rec­reation and Welfare Association elections.

Despite heavy campaigning by an opposition slate, members reelected the entire incumbent board.

"I'm pleased the entire board was re-elected," President Benja­min Fulton, NICHD, said. "It shows support for this past yea1·'s pro­gram1:1."

Opposition Seen as Beneficial He ll'egarded the opposition as

beneficial, howcwr, because it stim­ulated interest and gave the board an inkling of what others want.

First vice-president Dr. John Kal­berer, NCI, explained that th.is year, for the first time, people at NIH became interested in the R&W elootions. He attribuJted this to the strong publicity campaign.

Others elected to the Board of Directors a.re: John Land, NLM, second vice-president; Donald Cy­phers, NIAMD, treasurer, and Joan Genau, NIDR, sec:retaa:y.

NIH organizational units show­ing employee participation in ex• cess of 50 percent are: DBS, DRG, BEMT, NIDR, FIC, and NIGMS.

THE NIH RECORD

DCRT Computer Device; An Optical Page Reader; Will Increase Services

With the installa.tion in the fall of a fast, versat ile computer input device called an Optical Page Read­er, the Division of Computer Re­search and Technology will signifi­cantly increase its services to NIH.

Because the Reader has many po­tential applications, DORT estab­lished a task force to develop pro­cedures. Membexs are requesting employees to submit memoranda to the Optical Page Reader Task Force, Bldg. 12A, Rm. 2230, outlin­ing any project, large or small, that might lend itself to optical docu­ment processing.

Details Requested

The memol'11.Tldum should give a brief description of the proposed a pplication and include name, in­stitute, building, room number, and telephone extension of the person to be contacted for discussion of re­quirements.

A seminar has been scheduled for next Wednesday, July 15, from 9:30 to 11 a.m. in Bldg. 12A, Rm. 1024. The optical processing sys­tem will be discussed from the users point of view, and task force personnel will be on hand for ques­tions.

For reservations, contact the Technical Information Office, Ext. 65431.

The Optioal Page Reader is con­sidered versatile because it reeog­nizes letters, numbers and most of the special symbols of a standard optical font whether it is typed or p.rinted. It can also read handwrit­ten numerals and certain handwrit­ten letters.

Pote ntia I Is Great

The maohine is able to handle a mixture of machine printing, hand printing, and pencil ma.rks all lo­caited in the same document. Tabu­lar formats within regular running text are also easily processed be­cause .the machine can scan both vertically and ihorizontally.

The l!'eading and recognition op­eration of the device tak~ place at split second speeds, and is eco­nomical in projeets where a great deal of keypunching would other­wise have to be done.

Rise in Cost of l iving for May Increases Retirement Annuities

As a result of the 4.6 percent rise in the cos,t of living for May, em­ployees who retire on or before July 31 will receive an annuity in­crease of 5.6 percent.

The increase, which becomes ef­fective August 1, will be reflected in c;hecks received in September.

Any questions on this benefit or other retirement information should be directed to the B/ 1/D personnel officer.

Page 3: FILE COPY ecor - NIH Record · pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help ... achievements deserve special

THE NIH RECORD

Dr. Margaret Goldsmith, Exec. Secretary of DRG Study Section~ Retires

Dr. Margaret Towell Goldsmith recently retired as executive secre­tary of the Cardiovascular A Study Section in the Div>ision of Re­search Grants.

Dr. Goldsmith, who has served in the Federal Government for 24 years, came to DRG in 1963 from the N ati.onal Heart Institute.

She had been with NHI since 1959, first as a public health pro­gram analyst, and then as scien­tist-administrator {biological sci­ences) .

Dr. Goldsmith received her M.S. (1943) and Ph.D. (1944) degrees in Bacteniology from the Univer­sity of Maryland.

An appointment as assistant in the Biology Department of Colum­bia University started her career as a bacteriologist in 1937. Two years later she became an in­structor in the Bacter iology De­partment at the University of Maryland.

Her first position as a Federal employee was in the Bacteriology Laboratory of the Department of Agriculture in Beltsville. When she left there to come to NIH in 1959 she was chief of the labor­atory.

Dr. Goldsmith received a silver tray and laudatory scroll from her

Dr. Goldsmith is a membe r of several honorary frate rnol organizations as well as prafessionel organizations.

friends and colleagues at a retire­ment luncheon held in her honor.

She will serve as a consultant for the Cardiovascular A Study Section's round of meetings during the remainder of this year.

2 Donors Join Gallon Club Th e Clinical Center Blood

Bank reports that Sandra P. Hall, DRG, a.nd Grant C. Rig­gle, DRS, have joined the Gal­lon Donor Club.

In more ways than one, it pays to give ,blood.

For additional information call the Blood Bank, Ext. 64508.

July 8, 1970

Federal Program For Youths Emphasizes 'Marketable' Job Skills Through Training

Following an orientation meeting, participants dispersed into smalle r groups to discuss plans for the summer with supervisors.

By Bonnie Friedman Public Information Aide

"The emphasis of the Federal Summer Employment Program for Youtfu is to train a young person for 8 to 10 weeks so he comes away with a marketable job skill," explained Stefanie Singer, associate co­ordinator of the project.

Mrs. Singer is an assistant to F loyd Swanson, FSEPY coordina­tor.

The program recruits teenagers from the urban area and offers them responsible summer positions. "It is not a keep-the-kids-off-the­st1•eets program," Mrs. Singer added.

Each Government agency is as­signed a geographic area for re­cruitment. This year NIH concen­trated on Cardoza, Upper Cardoza, and Roosevelt High School. Of the approximate 400 Summer Youth Aids at NIH, 220 hail from these sections of Washington.

Two recruiters canvassed the

'Threshold' Film Receives Gold Medal at Festival

A gold medal was awarded at t he Atlanta International Film Festival to a movie sponsored by the Na­tional Institute of General Medical Sciences.

The film "Threshold . . . Re­se-aroh and the Care of People," was one of 920 en.tries :6rom 20 coun~ tries. It illustrates the dependence of modern medical care on research.

M. Daniel Ba,iley, formeT NIGMS information officer, accepte.d the old medal for the Institute on June 27.

Helen Neal, de,puty information officer of NIGMS, was project offi­cer for the film, w,hich was directed by Tracy Ward and produced by Audio Productions.

The NIGMS Information Office reports that since -i:ts release e-a.rly this year, the film has been seen by some two .and ,a half million tele­vision viewers as well as by thous­ands of members of professional and community groups.

area to interest teens in the pro­gram. Those who wished to par­ticipate could be certified at U. S. Employment Service Offices estab­lished in their high school coun­seling centers. Each prospective aid was then interviewed by two NIH employees before selected.

Summer aids work at a variety of positions from office and clerical work to lab and computer jobs.

"The program has come a long way since the early 60's," Mrs. Singer said. "It has evolved from keeping the kids off the streets to now actually teaching them some­thing."

In addition to the two coordina­tors, FSEPY this year employs the services of two professional guidance counselors. Their fisst al'ea of concentration is the sum­mer aids who do not have career or school plans for the fall. They try to find professions, not just jobs, for these youths.

Every aid is also assigned an immediate supervisor who works with him all summer.

(Se• YOUTHS, Paa• 6)

Stefanie Singer, associote coordinator of FSEPY, e xplains the registration book to Summer Youth Aids at the orientation meeting.

Page S

Malek Discusses Changes In Concepts and Values Of Public Administration

HEW Deputy Undersecret.ary Frederick V. Malek was the kick­off speaker a,t the first of a discus­sion series on "Changing Concept.s and Values of Public Admini:stra-, tion" held in the J ack Masur Audi­t()rium last June 19.

In his talk, Mr. Malek discussed fundamental problems in the man­agement and administration of Fed­eral programs and attempts to im­prove their ,efficiency so as to "do a better job" and obtain "maximum mileage" from them.

Discusses ' New Federalism'

"The New FedeTalism," the sub­ject of his talk is, he said, a broad concept aimed at bringing Govern­ment closer to the pe()ple by revers­ing the trend of power to Washing­ton.

Mr. Malek also discussed briefly the Federal Aissistance Streamlin­ing Task Force ( F AS'l') effort, which he described as a step-by­step analysis of HEW assis,tance programs.

It is designed, he s•aid, to stn:eam­line, simplify, and tighten their ad­ministration and to eliminate over­lapping and duplication.

There are 260 such HEW pl"O­grams, he noted, costing some $19 billion, 90 peircent of which goes out in grants-in-aid. The FAST project, he added, is only one~third complete.

ASPA Sponsors Series The discussion series, sponsored

by the American Society for Pub­lic Administration, is oriented to­wai·ds the. exchange of ideas be­tween public administrators at vari­ous organizational and career lev­els. It was undertaken on the ini­tiative of young interns in public administration.

Richard L . Segg,el, NIH Asso­ciate Director fo;r Administration, introduced Mr. Malek at the start of the program.

Graduate Courses Listed In New 1970-71 Catalog

The 1970-·71 catalog of the NIH G1,adua,te Program evening courses will be available July 15.

Biochemistry of the Visual Pro­ce;,s, one of t he new courses offered, will be taught by Dr. Hitoshi Shi­chi, N,ational Eye Institute.

Other new courses include Regu­lation of Intermediary Metabolism, Problems and Mechanisms of Evo­lution, Advanced Topics in Com­puter Programming, Stochastic Processes, and Scientists and Social Responsibility.

The new catalog may be obtained from Bldg. 31, Rm. 2B-25, or by calling Ext. 66371.

Page 4: FILE COPY ecor - NIH Record · pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help ... achievements deserve special

Page 4 July 8, 1970 THE NIH RECORD

AWARDS CEREMONY HONORS 35 EMPLOYEES (Continued from Pane 1)

virus studies." Dr. Harry V. Gelboin, chlef,

Chemistry Branch, Etiology, NCI, "For the excellence of hls research on the molecular biochemistry of carcinogenesis."

Dr. Clarence J. Gibbs, Jr., super­visory research microbiologist, Col­laborative and Field Research, N INDS, "In recognition of his sig­nificant research on virus induced central nervous system degenera­tion."

Dr. William J. Hadlow, head, Comparative Pathology Section, and acting head, Arbo an<l Chronic Viral Diseases Section, Rocky Mountain Laboratory, NIA ID, "Fe>r his pioneering research on slow viral infection in animals, leader­ship in comparative pathology, and influence on concepts about the eti­ology of human chronic degenera­tive diseases."

J ohn W. Hambleton, chief, Fi­nancial Management Staff, BEMT, "For far-reaching accomplishments in financial policy and planning in support of the health manpower programs of the National Insti­tutes of Health."

Thomas D. Hatch, Acting Direc­tor Division of Allied Health Man­po~er, BEMT, "In recognition of his leadership in the development of a national program supporting edu­cation and training in the allied health professions."

David F . Kefauver, forme1·ly as-

sociate director for Extramural Pre>grams, NLM, "In recognition of his record in the broad field of biomedical communications, an<l for the leadership and program planning that he provided ... "

Dr. Hilton B. Levy, head, Molec­ular Virology Section, Laborator~• of Viral Diseases, NIAID, "For research on the biochemical mecha­nisms of interferon and demon­stration of the anti-tumor effect of an interferon inducer, Poly I. P oly C, in tumor-bearing animals."

John C. McDougall, associate director for Program Services, NICHD, "Foi- his conti-ibutions to the field of public health adminis­tration and for providing services of signal quality to the scientific programs of 1Jhe National I nstitute of Child Health and Human Devel­opment." Original Research Noted

Dr. Donald L. Morton, head, Tu­mor Immunology Section, Sm·gery Branch, NCI , "For his original re­search in the field of immunology of animal and human neoplasms."

Dr. Robert L. Ringler, deputy director, NH LI, "For his imagina­tive dynamic leadership in devel­oping the Institut.e's program proj­ect granting mechanism and in im­plementing the N HLl's reorgani­zation to emphasize programmatic interest and strengthen program planning and evaluation."

Dr. Burton Mr. Fretts Dr. Gajdusek Dr. Gelboin

Dr. Hadlow Mr. Hambleton Mr. Hatch Mr. Kefauver

Dr. Griff Terry Ross, head, En­docrinology Service, and assistant chief, Endocrinology Branch, NCI, "For his pioneering studies of pi­tuitary ho11nones and the clinical applications of these studies to the treatment of diseases of man."

Peyton Stapp, associate director for Analysis and Statistics, DRG, "In recognition of his major con­tributions to the development and operation of an effective system for the management of extramural data for the National Institutes of H ealth."

Dr. Thomas A. \Valdmann, h~d, Immunophysiology Section, Metab­olism Branch, NCI, " F.or his con­tribution to our knowledge of ery­thropoiesis and immunology."

Dr. George Weiss, chief, P hysi­cal Sciences Laboratory, DCRT, " For his leadership and acumen in developing, inspiring, and guiding the Physical Sciences Laboratory, DCRT, and in rec.ogn:ition of his prolific. talents in applied mathe­matics."

Margaret D. West, formerly chief, Manpower Resources Staff, BEMT, "For her significant and continuing aecomplishments in re­search and analysis related to the nation's health manpower supply and needs."

Dr. Marjorie P . Wilson, assistant director for Program Planning and Evaluation, OD, "In 1·ecognitlicm of her important contributions to ihe mission of the National Institutes of Health in the areas of policy development, program design, in­stitutional relations, and organiza-

tional planning." The Meritorious Service Medal,

presented to Commissioned Officers in recognition of a single, particu­lady important achievement, a ca­reer 11otable for accomplishment in technical or professional fields or unusually high quality and initia­tive in leadership, was awarded to the following officers;

Dr. Samuel Baron, head, Cellu­lar Virology Sectio11, Laboratory of Viral Diseases, NIAI D, "In rec­ognition of his contributions to the knowledge of interferon, his leadership in interferon research, and his initiation of a scientific in­formation exchange program."

Achievements Cited Dr. FredeJ:ic C. BaTtter, chief,

Endocrinology Branch, Inti·amural Research, NHLI, "For his signifi­cant achievements in medical re­search over a broad area a11d most specifically for discovery of the syn­drome of juxtaglomerular hyper­plasia."

Dr. Robert L . Bowman, chief, L aboratory of Technical Develop­ment, N H LI, "In 1·ecoglllition of his development of the spectropho­tofluorometer which has revolution­ized certain aspects of analytical chemistry, and of his continuing creative leadership of a unique combination of talents in the ap­plication of engineering to biomedi­cal research that is regarded as a national resource."

Dr. Willard H. Eyestone, chief, Animal Resources B1·anch, BEl\1'1',

(Continued o,i Page 5)

Superior Service Honor Awards

Dr. Gibb,

Dr, Levy Mr. McDougall Dr. Morton

Dr, Ringler Dr. Ross Mr. Stapp Dr, Woldmonn Dr. Weiss Mrs. West Dr. Wilson

Page 5: FILE COPY ecor - NIH Record · pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help ... achievements deserve special

THE NIH RECORD

Dr. Boron Dr. Bortte r

Dr. Gordon Dr. Koyhoe

(Continued from Pags 4)

"In l'ecognition of his c.ontributions to national programs for primate 1-esearch and leadership in animal resource projects in the NIH in­tramural and extramural activi­ties."

Dr. John L. Fahey, chief, Immu­nology Branch, General Labora­tories and Clinics, NCI, "For de­vising therapeutic procedui-es to al­leviate the effect of diseases of pro­tein synthesis and his leadership of la1·ge NCI programs to explore the relationship of the immune system to cancer in man."

Dl'. John M. Frankel, dental di­rector, Division of Dental Health, BEMT, "In Tecognition of his su­perior service to the public in fur­thering the cause of dental health in the United States and for his valuable assistance in suppo1t of progress of dental health in other countries."

Helps Check Cholera Epidemic

Dr. Robert S. Gordon, Jr., clini­cal director, NIAMD, "For his contributions to the understanding of the physiologic role of free fatty acids in the blood, for his services in helping to check a cholera epi­demic in Pakistan, and for demon­strating outstanding leadership in clinical research administration."

Navy Band to Give Concert July 14 at CC East Patio

The United States Navy Band will p1,esent a concert for Clinie<1l Center patients on Tuesday, July 14, at 7:30 p.m. on the patio east of the Jack Masur Auditorium, CC.

In case of rain, the conceit will be held in the auditorium.

NIH employees, their fam­ilies and friends, ru,e invited, but patients will have priority in seating.

July 8, 1970

Meritorious Service Medals

Dr. Bowma n Dr. Eyestone

Dr. Rowe Dr. Tabor

Dr. Donald E. Kayhoe, chief, Transplantation Imm u no Io g y Branch, Collaborative Research Program, N IAID, "In recognition of his outstanding contributions in mobilizing and di1,ecting a collab­orative research effort in the field of tranpslantaJt:ion immunology."

Honore d for Virology Research

Dr. Wallace P. Rowe, chief, Lab­oratory of Viral Diseases, NIAID, "For his distinguished research in virology including the discovery of the adenoviruses and cytomegalo­viruses, characteri7lation of the ade11oviTus-SV 40 hybrid phenome­non and the defectiveness of mouse sarcoma viruses."

Dr. Herbert Tabor, chief, Lab­oratory of Biochemical Pharmacol­ogy, NIAMD, "In recognition of his studies of tlhe metabolism of histidine which have been of fun­damental importance in showing how this amino acid is metabolized in the animal and bacterial cell and for extensive information which he has contributed through studies of histamine and poly­amines."

Cancer Studies Noted

Dr. John H. Weisburger, head, Carcinogen Screening Section, Ex­perimental Pathology Branch, NCI, "For h i s extensive research achievements in the study of meta­bolic pathways for chemical carcin­ogens and of biochemical mecha­nisms in carcinogenesis and for his dedicated efforts in identifying and defining environmental cancer haz­ards as a basis for cancer preven­tion."

Dr. Raymond D. Zinn, fom1erly chief, Laboratory Aids Branch, DRS, "For his meritorious service in the conception and successful development of the NIH's unique Canine Blood Donor Colony."

Forty• year length.• of - service awards were presented to four NIH employees, two of whom have re-

Dr. Fahey Dr. Frankel

Dr. Weisburger Dr. Zinn

D. C. Health Department To Sponsor Free Tests

The D.C. DepaT<tment of Public Health is sponsoll'ing free health tests for anyone over 21 years of age at the Health Screening Clinic on the grounds of D.C. General Hospital.

They will be given in Area C, Room E-118, Old Psychiatry Build­ing.

Examinations include tests for glaucoma, anemia, hearing, heart disease, diabetes, and TB and other chest diseases.

For an a!}pointme11t call 626-7248.

AFGE Loc:al Announc:es Annual Elec:tion Winners

Loe.al 2419 AFGE recently held its annual ele~tion of office.rs wt a regular monthly mee,ting.

Those elected a,re: Rennie C. Vest, president; Lawrence E. Ingberg, fu·st vice-J}resident; Harry W. Wo­mack, seeond vice-president; Har­vey J. Bullock, third vice-president; Helen T. Re<!ves, secretary-treas­urer, and Hei,bei:,t; D. Jac~on, chief steward.

Employees are invited to attend meetings held on the founth Wed­nesday of each month in Bldg. 31 at 5:30 p.m. Officers may be con­tacted for the exact location.

tired: J 01·dan Bryan, foJ"merly with the Office of the Director, and Alice M. Laskey, who worked with the Division of Research Grants.

Thomas H. Loy, in the Office of Financial Management, Office of the Director, and Dr. Dean Burk, in the Laboratory of Biochemistry, National Cancer Institute, are still on duty here.

Page 5

Dr. Campbell to Direct DDH Dental Manpower Development Center

lh·. Edwa1·d Campbell, Division of Dental Health, BEMT, has been ap­pointed Dii-ecto~- of the Division's Dental Manpower Center in Louis­ville, Ky.

Dr. Campbell will diroot a train-· ing progmm ito expand the func­tions of dellltal assistant.s.

Unde,r his leade:rship, the Cen­ters activibioo will shut from exper­imental studies and research on the productivity of dentist.s to training membe,i,s of the dental profession­faculties of the scllools of dentistry and dental assistants, administra­tors of clinics rand health directors - in the use of auxiliaries whose functio-ns have boon increased.

Training Beg ins Next Fa II

Training in a,pplication of new concepts in group practice, public clinics, an d neighborhood health centers will begin in the fall for selected groups.

Dr. O.ampbell is a g:roduaite of the University of Tennessee School of Dentistry. He also holds a Mas,ter's Degree in Public Health from the University of Norrth Carolina.

He entered the Public Heal bh Service in 1955 and has had assign-

Or. Campbe ll heads o program which will assist members of the dental pro­fession to increase use of auxiliaries.

ment.s with DDH as regional dental oonsulbant, HEW Region IV, At­lanta, Ga., and as chief of the Com­munity Progr,ams Branch.

In August 1969, Dr. Campbell was appointe.d special assistant for Manpower Development at the Man.power Development Ce.nter, serving in tha,t capacity until his present appointment as Direcbor.

Is ABPH Diplomote

Dr. Campbell is a Diplomaitc of the Amerioan Board of Public Healrth, a member of the American Dental Association and the Ameri­can AJS.sociation of P ublic Health Dentists, ra.nd immediate past presi­dent of the Southea--n Branch of the American Public He-alith Associa­tion.

Page 6: FILE COPY ecor - NIH Record · pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help ... achievements deserve special

Page 6

DR. BRODIE (Continued from Paga 1)

a number of chemically "inert" com­pounds that are relatively specific in producing liver and kidney necro~ sis do so bhrough formation of al­kyla.ting agents that destroy the very cells which form them.

The Golden Plate Award of the American Academy of Achievement was prescnrod to Dr. Brodie during the ninth annual Salute to Excel­lence weekenQ Jm1e 25-27 in Dallas.

Dedicated to ~he inspiration of youth, the academy honored 50 leaders in the sciences, education, finance, politics, and the arts in "a salute to all men who give their bel.t efforts to their daily tasks."

Students Honored Also honored were some 200 hon­

or students from high schools across the nation who partidpa,ted in sem­inars and discussion groups with the na!;ional leaden;.

The Oscar B. Hunter Memorial Award was presented to Dr. Brodie by bhe Amell'ican Therapeutic So­ciety June 20 in Chicago for his "outstanding achievement in exper­imental therapeutics.''

He is the first non-M.D. honored with this award since it was estab­lished 15 years ago. At the presen­tati-On of the award, Dr. Brodie de­livei-ed a paper on "Biochemical Mechanisms of Drug Toxicity.''

For "a lasting contribution to the healbh and welfare of mankind" and foi- his "inspiring and fruitful in­fluence on student.~ and colleagues," Dr. Brodie was given an Honorary Doctc1· of Scie.nce Degree from the New York Medkal College at Com-

Dr. Brodie, in rece nt drug stud ies, has been conccntroting on the woy in which nerve impulses are transmitted in the central ne rvous syste m.

mencement Exercises on June 2. Dr. Brodie's early work at NIH

involved the application of chem­istry to pharmacology oopecially in the study of the interaction of drugs with the bodi~ that ingest them.

Through these studies he learned that proper drug dosage depends upon the level a drug must rooch in the blood if it is to be effective since different species of animals,

July 8, 1970

Capable Medical Education Jukebox at NLM Instructs and Illustrates Programs

medical education JUl<e O ----

Mary B. Clark, NLM acting section head and James A, Keeling , Reference Library technician, show how to operate the somewhat formidable looking ma­chine, Instructions are posted on the right, and reasons for the machine's development arc explained on the left.

The pushbutton age has come up with a medical education jukebox that instructs, records questions, collects suggestions and illustrates medical programs.

including man, may have widely varying responses to the same drug because they break it down at dif­ferent rates.

He showed that data such as weight and size can be useless in determining dosage if an investi­gator ignores the fact that the metabolic rates of two species may vary greatly.

Finding Aids Women, Newborns

In 1958 Dr. Brodie and his associ­ates made a discovexy of great practical value in prescribing drugs to pregnant women and newborn infants when they found that mam­mals do no,t acquire drug-d.estroy­i ng enzyme systems until sometime after birth.

More recently, Dr. Brodie's drug $tudies have concenti-ated on the way in which neirve impulses are transmitted in the central nervous syst.em. His studies have shown al, most unequivocally that nerve im­pulses in the cenitral nervous system are transmitted from cell to cell tl1rnugh neuxohumoral transmit­ters, including neurohormones, dop­amine, norepinephrine and seroto­nin.

This research suggests to D:r. Bt•odie bha,t the causes of mental illnCS<S may be due to faults in this complex biochemical nerve trans­mission system.

Dr. Brodie is a gz-aduate of McGill University and New York

The jukebox has been installed in the Reading Room of the Na­tional Library of Medicine.

It was developed in the Depart­ment of Postgraduate Medicine, Albany Medical College, under the direction of Dr. Frank M. Wool­sey. Funds from NLM's Extra­mural Programs were used to sup­port the production of the machine.

There are over 60 programs on medical subjects that may be se­lected via a pushbutton. Many of the programs are illustrated by synchronized slide tr.msparencies projected on a screen that is part of the unit. No program lasts long­er than 6 minutes.

Suggestions Collected

A built-in recorder collects sug­gestions for future programs and evaluations of present programs. Medical questions are also recorded and later answered through the mail by the faculty of Albany Med­ical College.

The medical education jukeboxes will be used in Community Hos­pital Leaming Centers.

These centers, developed by the Albany Regional Medical Program in New York State, disseminate medical knowledge and provide continuing education for members of health teams.

University Medical School. Before coming to NIH in 1950, be was a teacher and researcher at New York University.

THE NIH RECORD

YOUTHS (Continued from Pll!lo $)

The supervisors, all of whom are YOlunteers, submitted for consider­ation training profiles of clntie~. special programs, and marketable iob skills. Because the aim of the ·project is to expose the partici­J)ants to a profession, those jobs which did not offer developmental opportunities were eliminated from the program.

Seven young people, acting as the Youth Staff, assist with man­agement duties and counseling. They visit supervisors and aids on the job to help cope with problems such as communications, transpor­tation, lost checks, and schedules.

"One of the values of this," Mrs. Singer explained, "is that kids re­late bett.er to people their own age."

FSEPY participants are also given an option to take supple­mental courses while at NIH. If intei-ested, they may spend up to 4 hours a week in class.

Taught primarily by NIH staff members, the courses range from job skills and tutorial programs to social problems and special inter­est fields.

Legal Rights, How to Take 'l'ests, Contemporary Community Health Issues, Poetry, Office Pro­cedures, and Journalism are a few of the 20 courses offered.

"Most participants have a posi­tive reaction to the classes," the Associate Coordinator reported. "It is the first time many of them are

Youth Aids in one group intently dis­,uss their summer plons.

challenged in a class room situa­tion," Mrs. Singer said.

Classes began the week of July 6, and about 300 of the •teens are tak-· ing pa.rt.

At the end of the summer, an awai-ds program will recognize par­ticipants for outstanding service. Cash benefits and certificates of merit will be awarded.

Analyzing the long-term effects of the project, Mrs. Singer labeled it a success. She cited aids who 1-eturn for consecutive summers, those who are encouraged to return to school, and ones who find a life profession through their training.

"In the Inner City young people are limited in scope of what they can achieve, not in their abilities," she said. "NIH offers them an op­portunity to realize the.fr capabili­ties.''

Page 7: FILE COPY ecor - NIH Record · pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help ... achievements deserve special

THE NIH RECORD

Dr. Weisskopf Retires From NLM But Plans Return for Research

The young man who received his medical degree at the Masaryk University in Czechoslovakia in 1929 probably never thought that one day he would be retiring from the National Library of Medicine as a Medical Director in Public Health Service of the U.S.

Dr. Josef Jordan Weisskopf has been a Medical Literature Analyst at NLM since 1965. Along with his medical expertise, his knowledge of languages enabled him to index articles in Slavic, German, Czech, and Slovak journals.

He faced mandatory retirement in 1968 at age 64, but was twice granted a one-year extension.

From 1929 to 1932 Dr. Weisskopf was assistant professor for Social Medicine on the medical :faeulty of. Masaryk University. F or 6 years,

Dr. Weisskopf's varied me dical experi­ence helped to make his services at NLM so invaluable his mandatory re­tirement was twice extended.

until 1938, he was in private gen­eral practice and was an ambula­tory physician fo:r the Tuberculosis Clinic in Brno.

After his arrival in this country in 1939, he was tutor and college physician at St. John's College in Annapolis, Md.

Later he served as medical and information officer in the Czecho­slovalcian Embassy in Washington, D.C., and from 1945 to 1948 wo,rked with the United Relief and Reha­bilitation Admini.&tration.

Since 1948 he has been with the PHS, including service with the Di­vision of Foreign Quarantine in Boston and in New York.

Dr. Weisskopf was dubbed a "gentle" gentleman a,t his recent farewell luncheon. More than 50 friends and co-wOTkers attended the luncheon to honor the genial lin­guist and Mrs. Weisskopf. They have two children and six grand­children.

Now that he has retired, official­ly, Dr. Weisskopf admits tha,t his 5 years at NLM have sparked in him a special desire to do medical research at the Library. He may have retired, but now he will be busier than ever.

July 8, 1970 Page 7

DR. BAKER (Continued fro,r, P<>q• 1)

For 2 years he served as assist­ant to the NIH Associate Director for lntramul'al Research, return­ing to NCI in 1958 as assistant rlirector. From 1960 to 1961 he also served as acting scientific di­rector of t he Cancer Institute.

In 1961 Dr. Baker was appointed NCI associate director for Pro­gram, and was named scientific di-1·e.ctor for Etiology in 1967.

Served on Cancer Journal Dul'ing his career Dr. Raker has

also been an associate editor of the Journal of the National Cancer In­stitute; secretary of the Division of Biological Chemistry, American Chemical Society; a member of the National Research Council Sub­committee on Amino Acids, Com­mittee on Biological Chemistry, Di­vision of Chemistry and Chemical Technology, and Councillor of the American Chemical Society.

He is Director-at-Large and un­til 1·ecently was a member of the Advisory Committee on Institu­tional Research Grants of the American Cancer Society; and a member of the Editorial Advisory Board of the journal Cancer.

Dr. Baker is a member of the American Society of Biological Chemists, American Association for Cancer Research, American Chemical Society (Division of Bio­logical Chemistry), AMA, and So­ciety for Experimental Biology and Medicine.

He has written a number of ar­ticles on cancer and biochemical research and on research planning and administration.

Dr. Baker holds the rank of Med­ical Director in the PHS Commis­sioned Corps.

Dr. Ramming Receives Award for Research

Dr. Kenneth P. Ramming, who completed 3 years as a Clinical AJJ­sociate here on June 30, recently received the Mead Johnson Excel­lence of Research Award.

The award, which includes $500 and a plaque, was presented at the National Research Forum of the Student American Medical AJJsoci­ation-University of Texas Medical Branch, in Galveston.

The honor was bestowed on Dr. Ramming because of his research on the transfer of tumor immunity with ribonucleic acid extracted from the lymphoid organs of spe­cifically immunized animals.

Dr. Ramming's work on animal tumo1'S while he was on the staff of the NCI Surgery Branch may lead to future applications in com­batting tumor growth in humans by enhanching the body's immune de­fense mechanisms against tumor antigens.

He presented a paper on his re-

Presterilized Disposable Envelope Kidney Proves Time-Saving, Economical in Trials

A disposable, presterilized, artificial kidney may soon replace types that take patients many hours to sterilize prior to use in home dialysis. The new "Envelope Kidney," which has already successfully passed ex­tensive clinical trials, will make it possible to reduce blood-cleansing time.

The Envelope Kidney was de­vised by Dr. Yukihiko Nose and associates of the Cleveland Clinic Foundation with the aid of a con­tract from the Artificial Kidney Program of t he National Institute of Arthritis and Metabolic Dis­eases.

It is essentially a sealed sand­wich of Cuprophan PT-150 mem­branes (a special type of cello­phane) supported externally by a fiber screen. Blood ports for at­tachment to the patient's circula­tion are included within each sealed package.

The new Envelope Kidney is de­signed for use with the conven­tional Kii! artificial kidney ma­chine.

In dialysis, blood flows over a cellop'hane membrane and impuri­ties pass from the blood through small pores in the membrane into a dialysis solution being circulated against the membrane by the ap­paratus.

Most patients require two to three treatments a week for pe­riods of 6 to 14 hours; thus any preparation time saved becomes a great advantage.

Because the membranes of the Envelope Kidney are presterilized with ethylene oxide gas, the pa­tient or his family no longer must begin assembly of the artificial

Dr. He nry M. Kissmon, a forme r NHI employee, hos been deto iled from the Food and Drug Administration to heod the Toxicology Information Program of the Notional library of Medicine's Specialized Information Services.

search, "The Tuansfer of Tumo1·­Specinc Immunity with Ribonucleic Acid," at the AMA 11-nnual meeting in Chicago on June 23.

Dr. Ramming is now a senior resident in General and Thoracic SurgeTy at Duke University Medi­cal Center.

The "Enve lope Kidney" -o presteril­ized sandwich of cellophane mem­branes developed through a n NIAMD contract- is placed aver the conven­t ional Kiil artificial kidney machine with which it is used. Prepackaged En­velope Kidney saves preparation time.

kidney 8 to 10 hours prior to di­alysis to allow for sterilization \vith a strong-smelling formalde­hyde solution.

With the new Envelope Kidney, assembly may begin only am hour prior to dialysis, and can be com­pleted by one person alone. This is of significant value in facilitat­ing dialysis in the home, a treat­ment method which is considerably less costly than extremely expen­sive hospital dialysis.

The cost of a pair of envelopes, presterilized and ready for use in a double layer Kiil artificial kid­ney is approximately $6, as com­pared with $17 for a prepukaged coil-type dialysis canister, the only other presterilized dialysis unit commel'cia\ly available at the pres­ent time.

No Side Effe cts

Preliminary clinical results from trials of the Envelope Kidney­more than 200 dialyses with 14 paitients-have bee n excellent, with no adverse reactions and with blood purification performance as good as or better than ,vith stand­ard cellophane membranes in the Kiil apparatus.

In the United States today an estimated 55,000 individuals die each year as a result of irrevers­ible kidney failure. To many of these the artificial kidney is a per ­manent lifesaving treatment.

Kidney transplantation, too, de­pends for its success on the use of artificial kidneys. Transplant can­didates must be maintained b:v di­alysis until a suitable donor kidney can be found for them.

Dialysis also is used to support these patients postoperatively, and is essential for saving their lives if the transplanted kidney is even­tually rejected by the body.

Page 8: FILE COPY ecor - NIH Record · pow~l'S continues to interest the medical profession. Although maggots were used briefly during both World Wars to help ... achievements deserve special

Page 8 July 8, 1970 THE NIH RECORD

Helmet Design That Allows For Rotation Of Head May Prevent Brain Injury

A helmeted motorcyclist, thrown from his bike, or a football player incurring violent impacts share a common hazard-brain injury.

This is because helmets, as presently desi)?ned, do not adequately pro­tect the brain, according to Dr. Ayub K. Ommaya, associate neuro­surgeon in the Surgical Neurology Branch, National Institute of Neu­tological Diseases and Stroke.

He made these comments dur­ing a recent meeting of the Ameri­can Society of Mechanical Engi­neers in Washington, D. C.

Dr. Ommaya, who has been in charge of the Institute's Head In­jury Program since its inception 6 years ago, was made an execu­tive affiliate member of the So­ciety.

Jmportont Aspect Ignored H e is one of five medical doctors

in the society's ,history invited to speak at its annual Biomechanics and Human F actors Symposium.

The design of motorcycle, foot­ball, and crash helmets, the pad­ding of car interiors, and the de­sign of car seats and head rests ignore an important aspect of brain injury- that of rotation of the head on the neck, he notl-'<I.

"All existing head protection standards set up by the American Standllll'ds Institute-on which de­sign of helmets is based-center on the assumption that brain injury is related to linear forces," he said.

"They don't consider rotation of ithe head on the neck.

"We have found," he continued, "that rotation is actually more im­portant than linear motion, and that the 'whiplash' type of head motions, if severe enough, can cause brain !hemorrhages without the head being struck directly."

While existing helmets are good skull protectors, they do not pro-

Dr. Virginia J. Evans Reelected Vice President Of Tissue Culturn Ass'n

Dr. Virgini,a J. Evans, head of the Tissue Culture Section, Nation­al Cancer Institute, has been re­elected vice-pres,ident of the Tissue Cul ture Association.

Dr. Evans was local committee chairman of the association's 21st annual meeting held June 15-18 in Washington, D.C.

Dr. Katherine Sanforo, also of NCI, served as co-chairman.

The 175 papers presented by sci­entists, a number of whom were from NIH, covered suoh topic,s as viruses, hormones, oncology, and environmental biology in relation to t issue culture.

The Wilton Earle Awa.rd, estab­lished by the .association in honor of the late head of NOI's Tissue Culture Section, will be given for the first time at next year's meet­ing to a graduate student p1·esent­ing an oul:6tanding paper.

Or. Ommaya, o neurosurgeon, hos been mode on execut ive affiliate mem­ber of the American Society of Me­chanicol Engineers.

tect the brain. Although prevent­ing skull bending or fracture, they cannot prevent subsequent head ro­tation caused by the blow, Dr. Om­maya added.

He presented a detailed summa1·y of data collected in the Head In­jury Program showing that severe brain damage could be produced in animals from rotation alone--such as in a whiplash situation.

Theory Moy Aid Design

His data also showed that wea1·­ing a stiff collar markedly reduces brain injuries resulting from a di­rect blow to the head by 1·educing resultant head rotation.

Adapting animal data to factor$ concerning man, Dr. Ommaya pre­sented his theory for scaling from one to the other. He believes his theory can provide the basis for improved design of helmets and other brain protecting devices by engineers.

"Car head rests can actually be dangerous if not properly designed and positioned," he said. "Quite often such head rests only come up to a driver's or passenger's neck. They tlh<!refore fail to arrest head rota.tion and can cause trauma to the neck as well."

1nflatable air bags or collapsible scats which could absorb head and body motions after impact could help to alleviate rotation of the head and subsequent brain injury.

Stressing the importance of bio­mechanics as a tool for improved prevention, protection, and treat­men.t of head and spinal cord in­jury, he emphasized its application to understanding the responses of the nervous system at the cellular level.

"ln conjunction with physiopath­ology, it is providing us witlh a new

MAGGOTS (C,,nti-rmed from Pa,ge 1)

into larvae, or maggots, which pu­pate and become adult flies.

During this metamorphosis dra­matic transfo1mations in structure ;i.nd physiology occur, ancl Dr. Lev­,:nbook can examine these biochemi­cal changes in tissue buildup and breakdown which may pi-ov:ide in­sight into changes in human me­tabolism.

Occasionally, and as a side-line to his scientific work with blow­flies, he ships batches of stEn;lized maggots from his labo1·atory to hospitals for wound treatment.

When a physician at the l\1etho­dist Memorial H ospital, St. Joseph, Mo., called the Department of Ag-1·iculture to obtain maggots, he was referred to NIH and Dr. Lev­enbook, one of the few U. S. re­searchers who raises sterile blow­fly maggots.

He sterilizes the eggs with so­di um hypochlorite--the .active in­gredient in many commercial bleaches-and grows them on a sterile medium. Since humans have been known to contract lockjaw (tetanus) from maggot infesta­tions, the maggots used in wound treatment must be sterile.

Heolthy Tissue Not Attacke d It is the third-stage maggot that

is placed on the patient's gangre­nous wounds. After 3 to 4 days they have thorouglhly cleansed the bacteria-loaded wounds by ingest­ing bacteria and necrotic tissue. Healthy tissue is not attacked.

The larvae also aid in wound healing through excretion of a sub­stance called allantoin, a compound

appl'Oach to nervous system rn­sponse to injury-how shape and structure are altered by trauma.

" To accomplish this, we need closer collaboration between engi­neers and life scientists, and ex­cellence in both fields," Dr. Om­maya said.

Senator Hill Sculpture Will Remain at NLM Until Center Is Ready

A sculptured head of Lister Hill, former United States Senator from Alabama, has been loaned to the National Library of Medicine by Mrs. Albert D. Lasker of New York City.

The sculpture by Robert Berks is in bhe Library's public catalog area, just off the main lobby.

Senator Hill was for many years a strong advocate of improved bio­medioal oommunications.

In a letter to Dr. Martin M. Cum­mings, NLM Director, Mrs. Lasker asked 1lhat the sculpture remain at the Library until the Lister Hill National Center for Biomedical Communications building is com­pleted.

The new building is to be erooted adjacent bo NLM, according to present plans.

which promotes healthy tissue growth.

This method has also proved helpful in treating osteomyeHtis, a bone inflammation caused by pus­fol'!!ling infectious organisms 1,lhich have entered an open wound.

Since circulation is impaired in these patients, trea,tment with con­ventional oral and injected anti­biotic drugs, which must be carried via the blood stream to the wound, is not always 100 percent success­ful. Maggot treatment skirts this obstacle through direct treatment of the wound.

The antibiotic Tegimcn, some­times a hardship for the seriously ill patient, is thus circumvented.

There are, however, barriers to wider use of this form of therapy. Maggots are impractical because they can never be stacked on the druggists' shelves.

Further, aesthetic reasons alone would deter most patients who might benefit most from their use. As a result, recurring new inter­est over the years in myiasis has not been long las ting.

CC practical nurses, at th.iir recent annual conference on The Nursing Care of the Physically Dependent Patient, discussed trends in providing core to patients with various physical ond me ntal disabilities. The Conference, which drew o large audience of professional and student visitors, included talks, dem­onstrat ions, slide presentotions, and exhibits.