Faculty of Medicine, University of Novi Sad Department of Pathology school year 2018/2019

INFORMATIONS OF THE COURSE PATHOLOGICAL ANATOMY

The information is intended for regular third-year students of the Faculty of Medicine in Novi Sad - the integrated study of medicine.

This guide contains basic information about the course, information of the total hours number, the organization of theoretical and practical teaching, the curriculum, the list of histological and macroscopic preparation, informations of taking exams, exam questions and a list of basic and supplementary textbooks.

We believe that this type of information will help students to master knowledge successfully related to this course and studies in general.

Authors Prof . dr Slavica Knežević Usaj , Head of the Department Assoc. Prof dr. Milana Panjković, Deputy Head of the Department

I. GENERAL INFORMATION Pathology is held during V (5 +5 ) and VI (3 +3) semester with a total number of 120 hours of

theoretical and 120 hours of practical training. Theoretical teaching is held in the amphitheaters of Faculty of Medicine by the schedual that

is going to be published at the beginning of the semester by the student service.

Practical classes are held at: 1. Department of Pathology and Histology, Faculty of Medicine in Novi Sad. 2. Center for Pathology, Institute for Pulmonary Diseases in Sremska Kamenica 3. Department of Patho-anatomical and Cytological Diagnostics, Institute for Oncology in Sremska Kamenica.

Theoretical and practical lectures of the course lead : 1. Two full professors 2. One associate professor 3. Three assistant professors 4. Two teaching assistants

II. THEORETICAL TEACHING PROGRAM

A. GENERAL PATHOLOGY 45 hours

* INTRODUCTION TO PATHOLOGY 1 hour * MOLECULAR AND SUBCELLULAR PATHOLOGY 4 hours * CELLULAR PATHOLOGY AND DEGENERATIONS - 5 hours * ADAPTATION- 5 hours * CIRCULATORY DISORDERS- 5 hours * GENERAL PATHOLOGY OF NEOPLASIA- 8 hours * MOLECULAR BASIS OF CANCER -2 hours

* ENVIRONMENTAL DISEASES - 3 hours * INFLAMMATIONS - 4 hours * REGENERATION, REPARATION AND ADAPTATION - 1 hours * GENETIC AND DEVELOPMENTAL DISORDERS - 2 hours * IMMUNOPATHOLOGY- 5 hours

B. SPECIAL PATHOLOGY 75 hours

* PATHOLOGY OF LYMPHOHISTIOCYTIC SYSTEM - 5 hours * PATHOLOGY OF ENDOCRINE SYSTEM - 5 hours * MUSCULOSKELETAL DISORDERS - 4 hours * PATHOLOGY OF SKIN - 5 hours * PATHOLOGY OF LUNG AND PLEURA - 10 hours * PATHOLOGY OF GASTROINTESTINAL AND HEPATOBILLIARY SYSTEM AND PANCREAS - 12 hours * PATHOLOGY OF FEMALE GENITAL SYSTEM AND BREAST - 10 hours * PATHOLOGY OF URINARY SYSTEM AND MALE GENITAL ORGANS - 9 hours * PATHOLOGY OF HEART AND BLOOD VESSELS - 9 hours * PATHOLOGY OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM - 6 hours

III. PRACTICAL TEACHING PROGRAM

Practical taeching of the course will be held in all of the above teaching facilities according to the plan:

- 5 hours per week during the winter semester - 3 hours per week during the summer semester.

Histological diagnostics During the semester, students attend the exercises of histological diagnostics based on

schedule that is published under the general schedule for students of Medicine in English. These exercises are held in the microscopy hall at the Department of Pathology and Histology

at the first floor of the Medical Faculty in Novi Sad. Introductory lessons for histological exercises are performed in the hall for microscopy at the

Department of Pathology and Histology at the first floor of Medicine. Students are required to wear white laboratory coats during practical teaching.

From the academic year 2015/2016, the teaching of histopathological diagnosis is performed on computers with scanned histological slides, which will allow interactive teaching and easier way to master the subject matter of this type of diagnosis. Department believes that the introduction of digital microscopic diagnosis is of great importance to the improvement and modernization of the teaching of pathological anatomy. This type of instruction will allow students to review and practice all slides throughout the year so there is no need for performing the pre-examination exercises.

List of slides for histological practice :

Slide title Page of slide in handbook

1 Atrophia fusca myocardii (Brown myocardial atrophy) 90

Atrophia testis (Testicular atrophy) 92

Atrophia senilis endometrii (Senile endometrial atrophy) 91

2 Degeneratio parenchymatosa renis (Renal parenchymal degeneration)

115

Steatosis hepatis (Fatty liver) 159

Carcinoma medullare glandulae thyreoideae cum stroma amyloides (Medullar carcinoma of the thyroid gland with stromal amyloid deposits)

102

3 Haemosiderosis pulmonis (Pulmonary hemosiderosis) 128

Calcificationes dystrophicae glandulae thyreoideae (Dystrophic calcification of the tyroid gland)

96

Atherosclerosis arteriae (Atherosclerosis of the artery) 89

Necrosis textus adiposi (Fat necrosis) 146

4 Hyperaemia passiva hepatis (Passive hyperemia of the liver)

130

Infarctus anaemicus recens renis (Recent anemic kidney infarction)

134

Infarctus anaemicus recens myocardii (Recent anemic myocardial infarction)

133

Infarctus haemorrhagicus pulmonis (Hemorrhagic infarction of the lung)

135

5 Cicatrix postinfarctum myocardii (Postinfarction scar of the myocardium)

111

Granulationes nonspecificae (Nonspecific granulation tissue)

123

Granuloma corporis alieni pleurae parietalis (Pleural foreign body granuloma)

124

Hyperplasia prostatae cum prostatitide chronica (Prostatic hyperplasia with chronic prostatitis)

132

6 Abscessus subacutus cutis (Subacute abscess of the skin) 75

Appendicitis phlegmonoso - purulenta acuta (Acute phlegmonous appendicitis)

88

Cholecystitis chronica simplex (Simple chronic cholecystitis)

108

Cholecystitis gangraenosa acuta (Acute gangrenous cholecystitis)

109

7 Affectus primarius tuberculosis pulmonis (Primary tuberculous affect of the lung)

87

Bronchopneumonia tuberculosa caseosa (Tuberculous caseous bronchopneumonia)

95

Tuberculosis miliaris pulmonis (Miliary tuberculosis of the lung)

163

Pleuritis granulomatosa necroticans (Necrotic granulomatous pleuritis)

152

8 Fibroma durum (Hard fibroma) 119

Fibroadenoma mammae (Breast fibroadenoma) 118

Papilloma intraductale mammae (Intraductal papilloma of the breast)

151

Epulis fibromatosus gigantocellularis (Giant cell fibromatous epulis)

117

9 Haemangioma cavernosum hepatis (Cavernous hemangioma of the liver)

126

Haemangioma capillare cutis (Capillary hemangioma of the skin)

125

Liposarcoma (Liposarcoma) 138

Osteosarcoma (Osteosarcoma) 150

10 Carcinoma ductale infiltrativum mammae (Invasive ductal carcinoma of the breast)

99

Carcinoma ductale infiltrativum mammae - estrogenski receptori (Invasive ductal carcinoma of the breast – estrogen receptors)

100

Adenocarcinoma intestini crassi (Colorectal adenocarcinoma)

77

Carcinoma planocellulare in situ portionis vaginalis uteri (Squamous cell carcinoma in situ of the vaginal portion of the uterus)

101

11 Adenoma folliculare glandulae thyreoideae (Follicular adenoma of the thyroid gland)

84

Struma diffusa hyperthyreotica glandulae thyreoideae (Diffuse toxic goiter of the thyroid gland)

160

Carcinoma papillare glandulae thyreoideae (Papillary carcinoma of the thyroid gland)

105

Tumor carcinoides intestini tenui (Carcinoid tumor of the small intestine)

164

12 Bronchitis chronica catarrhalis (Chronic catarrhal bronchitis)

93

Emphysema panacinare pulmonum (Panacinar emphysema of the lung)

116

Bronchopneumonia fibrinoso - purulenta acuta (Acute fibrinosopurulent bronchopneumonia)

94

Pneumonia in cursu organisationis (The organising pneumonia)

153

13 Sarcoidosis pulmonis (Sarcoidosis of the lung) 156

Oedema acutum pulmonis (Acute pulmonary edema) 148

Membranae hyalineae pulmonis (Hyaline membrane of the lung)

142

14 Carcinoma microcellulare bronchi (Microcellular carcinoma of the lung)

103

Adenocarcinoma pulmonis (Adenocarcinoma of the lung) 79

Carcinoma squamocellulare bronchi (Squamous cell carcinoma of the lung)

107

15 Lymphadenitis reactiva ( Reactive lymphadenitis) 139

Morbus Hodgkin - typus sclerosis nodularis (Morbus Hodgkin – nodular sclerosis type)

144

Lymphoma non - Hodgkin - typus diffusus (Diffuse large B-cell lymphoma)

140

Adenocarcinoma metastaticum lymphonodi (Metastatic adenocarcinoma in the lymph node)

78

16 Osteomyelitis purulenta acuta (Chronic purulent exacerbate osteomyelitis)

149

Synovitis villonodularis (Villonodular synovitis) 161

Chondrosarcoma (Chondrosarcoma) 110

17 Verruca vulgaris cutis (Common wart of skin) 166

Naevus intradermalis verrucosus cutis (Intradermal verrucous nevus of skin)

145

Melanoma malignum cutis (Malignant melanoma of skin) 141

Carcinoma baseocellulare cutis (Basocellular carcinoma of skin)

98

Keratosis seborrhoica cutis (Seborrheic keratosis of the skin)

136

18 Gastritis chronica atrophicans (Chronic atrophic gastritis) 120

Ulcus chronicum ventriculi (Chronic gastric ulcer) 165

Adenocarcinoma ventriculi - typus diffusus (Adenocarcinoma of the stomach – signet ring cell type)

82

Adenoma tubulo - villosum intestini crassi (Tubulo - villous adenoma of the large intestine)

86

Colitis chronica ulcerosa (Chronic ulcerative colitis) 113

19 Cystis echinococcica hepatis (Echinococcus cyst of the liver)

114

Cirrhosis micronodularis hepatis (Micronodular cirrhosis of the liver)

112

Hepatitis chronica activa (Chronic active hepatitis) 129

Steatonecrosis pancreatis (Steatonecrosis of the pancreas) 158

20 Adenoma pleomorphum glandulae salivalis (Pleomorphic adenoma of the salivary gland)

85

Adenolymphoma glandulae salivalis (Adenolymphoma of salivary gland)

83

Carcinoma adenocysticum glandulae salivalis (Adenoid cystic carcinoma of salivary gland)

97

21 Hyperplasia endometrii simplex (Simple endometrial hyperplasia)

131

Teratoma maturum ovarii (Mature ovarian teratoma) 162

Adenocarcinoma endometrii (Endometrial adenocarcinoma) 76

Leiomyoma hyalineum (Hyalinizing leiomyoma) 137

22 Pyelonephritis purulenta acuta abscedens (Acute suppurative pyelonephritis)

155

Pyelonephrinitis chronica (Chronic pyelonephritis) 154

Adenocarcinoma renis (Renal cell adenocarcinoma) 81

Glomerulopathia diabetica (Diabetic glomerulopathy) 122

23 Adenocarcinoma prostatae (Prostatic adenocarcinoma) 80

Seminoma testis (Testicular seminoma) 157

Carcinoma papillare vesicae urinariae (Papillary bladder cancer)

106

24 Haemorrhagia recens cerebri (Brain hemorrhage) 127

Neurinoma (Neurinoma) 147

Glioblastoma multiforme (Glioblastoma multiforme) 121

Meningeoma (Meningioma) 143

Macroscopic diagnostics - MUSEUM GROSS PREPARATIONS

During the winter and summer semester, students attend the exercises of the macroscopic (gross) diagnostics during one hour per week according to schedule that is published as general schedule for students of Medicine.

These exercises are held in the hall for macroscopic preparations of the Department of Pathology and Histology on the first floor of the Medical Faculty in Novi Sad.

Students demonstrate the museum preparations with a special request for independent active work in the description and diagnosis of the preparation.

Students are able to review the museum preparations freely.

List of macroscopic preparations

Practice Diagnosis Specimen number

1 Atrophia e compressione hepatis (Atrophy of the liver due to compression). 1 Cystis hydatidosa lienis. Atrophia e compressione lienis. (Hydatid cyst of the spleen. Atrophy of the spleen due to compression.) 2

2 Hypertrophia myocardii et dilatatio ventriculorum cordis (Cor bovinum). (Myocardial hypertrophy and ventricular dilatation of the heart). 3 Hypetrophia prostatae. Hypertrophia trabecularis vesicae urinariae. (Hypertrophy of the prostate. Trabecular hypertrophy of the urinary bladder.) 4

3 Amyloidosis lienis (sago slezina) (Amyloidosis of the spleen) 6 Anthracosis lymphonodorum bronchopulmonalium et pulmonis (Anthracosis of the lung and bronchopulmonary lymphnodes). 11 Hyalinosis pleurae parietalis (Hyalinosis of the parietal pleura). 7

4 Atherosclerosis arteriarum baseos cerebri (Atherosclerosis of the arteries at the base of the brain). 10 Haemorrhagia recens cerebri (Recent cerebral hemorrhage). 15 Haematocephalus internus (Internal hematocephalus). 79

5 Infarctus anaemicus lienis (Anemic infarct of the spleen) 13 Embolia thrombotica recens trunci pulmonalis et arteriarum pulmonalium (Recent thromboembolism of pulmonary trunk and pulmonary arteries) . 14

6 Cicatrix cutis (Skin scar). 17 Hypoplasia renis (Hypoplasia of the kidney). 18 Cystes congenitales ovarii bilaterales (Congenital ovarian cysts). 96

7 Abscessus cerebri (Brain abscess). 7 Laryngotracheobronchitis pseudomembranacea (Pseudomemranous laryngotracheobronchitis). 22

8 Complexus primarius tuberculosis (Primary complex of pulmonary tuberculosis). 23 Tuberculosis miliaris pulmonis (Miliary pulmonary tuberculosis). 24 Tuberculosis caseosa cavernosa pulmonis sinistri (Caseous pulmonary tuberculosis with formation of tuberculous caverna). 25

9 Fibroma pendulans (Pendular fibroma) 27 Papilloma laryngis (Papilloma of the larynx) 28

10 Naevus pigmentosus verrucosus cutis (Pigmented verrucous nevus of the skin). 31 Myxoma (pseudomyxoma) atrii sinistri cordis (Left atrial myxoma - pseudomyxoma). 33

11 Struma glandulae thyroideae (Struma of thyroid gland). 39 Carcinoma glandulae thyroideae (Carcinoma of thyroid gland). 38

12 Carcinoma exulceratum mammae (Exulcerating breast carcinoma). 34 Tumor malignus metastaticus pulmonis sinistri (Metastases in the left lung). 36 Tumor malignus metastaticus in hepate (Metastases in the liver). 100

13 Myeloma multiplex (plasmocytoma) calvariae (Multiple myeloma - plasmacytoma of skull cap). 40 Lymphoma lienis (Lymphoma of the spleen). 41

14 Carcinoma metastaticum corporis vertebrae thoracalis (Metastatic carcinoma of thoracic vertebral bodies). 42 Melanoma metastaticum cordis (Metastatic melanoma of the heart). 46

15

Bronchiectasiae cylindricae lobi inferioris pulmonis sinistri (Cylindrical bronchiectasis in the lower lobe of left lung). 51 Mesothelioma malignum pleurae (Malignant pleural mesothelioma). 52 Carcinoma bronchi lobi superioris pulmonis infiltrans mediastini (Bronchal carcinoma of upper pulmonary lobe with infiltration of mediastinum). 90

16 Foramen ovale apertum (Patent foramen ovale). 53 Endocarditis bacterialis (Bacterial endeocarditis). 54 Epicarditis fibrinosa acuta - Cor villosum (Acute fibrinous pericarditis). 56

17 Cystes retentiones renis (Retention cysts of the kidney). 57 Ren macropolycysticus (Polycystic kidney disease). 59

18 Ureter duplex (Duplicated ureter). 60 Contentum sanguineum vesicae urinariae (Hemorrhagic content of the urinary bladder). 62

19 Carcinoma papillare vesicae urinariae (Papillary carcinoma of the urinary bladder). 64

Adenocarcinoma renis (Renal adenocarcinoma). 35

20 Leiomyomata subserosum et intramurale uteri (Subserosal and intramural leiomyomas of the womb). 66 Diverticulum Meckeli intestini tenuis (Meckel's diverticulum of the small intestine). 69 Diverticulosis intestini crassi (Diverticulosis of the large intestine). 70

21 Ulcus chronicum ventriculi (Chronic gastric ulcer). 73 Ulcus chronicum ventriculi ad pancreatem penetrans (Chronic gastric ulcer penetrating to the pancreas). 74 Carcinoma exulceratum ventriculi (Ulcerated gastric carcinoma). 75

22 Carcinoma stenosans intestini crassi (Stenosing carcinoma of the large intestine). 76 Carcinoma exophyticum intestini crassi (Exophyting carcinoma of thr large intestine). 91 Cirrhosis micro- et macronodularis hepatis (Micro and macronodular liver cirrhosis). 77

23 Aneurysma arteriae basilaris cerebri (Aneurysm of basilar artery of the brain). 78 Meningeoma regionis frontalis haemispheri dextri cerebri (Meningioma in frontal region of right cerebral hemisphere). 82 Neurinoma anguli pontocerebellaris dextri (Neurinoma of the right cerebellopontine angle). 83

AUTOPSY During the school year, students will be self-divided in small groups in order to attend the autopsy. Autopsies are obligatory. During the school year, student must attend at least two autopsies (1 located in Novi Sad and one located in Sremska Kamenica) without which student will not be able to get the signature at the end of school year.

After students attend a complete autopsy, they will be signed in the index (for this section of practical teaching).

Students are trained to observe morphological changes, especially by the ways of thinking and reasoning in pathology and to form an autopsy conclusion.

Informations about the autopsies in Sremska Kamenica are available on weekdays and Saturdays at 7.30 at telephone 480-5322 and in Novi Sad at telephone 484-3313 from 8:00 am.

QUESTIONS FOR ORAL EXAM 1. Causes of cellular damages 2. Mechanisms of cellular damages 3. Ischemic and hydropic cellular injury 4. Intracellular lipid accumulation 5. Carbohydrates and other accumulations 6. Necrosis and apoptosis 7. Endogenous pigmentations 8. Exogenous pigmentations 9. Pathologic calcifications 10. Hyalinosis 11. Stone forming 12. Amyloidosis 13. Atrophy 14. Hypertrophy and hyperplasia 15. Metaplasia and dysplasia 16. Reparation 17. Wound healing 18. Hemodynamic changes in inflammation and cellular components of inflammation 19. Serous, fibrinous and catarrhal inflammation 20. Purulent inflammation 21. Hemorrhagic and gangrenous inflammation 22. Chronic inflammation 23. Chronic granulommatous inflammation 24. General pathology of tuberculosis 25. Syphilis (Lues) 26. Viral infection 27. Fungal infection 28. Parasitic infection 29. Burns and frost bites 30. Radiation changes 31. Changes in atmospheric pressure (blast and crash syndrome) 32. Hypersensitive reactions 33. Mechanism of autoimmune diseases 34. Systemic lupus erythematosus 35. Systemic sclerosis 36. Polymyosistis, dermatomyositis, Sjogren syndrome 37. Rheumatoid arthritis 38. AIDS 39. Graft rejection morphology 40. Venous hyperemia 41. Arterial anemia 42. Infarction 43. Thrombosis 44. Embolia 45. Hemorrhage 46. Edema 47. Shock 48. Developmental malformation - classification

49. Molecular basis and classification of genetic diseases 50. Monogenic autosomal dominant diseases 51. Monogenic autosomal recessive diseases 52. Chromosomal disturbances 53. Basic diagnostic methods in pathology 54. Definition and classification of tumors 55. Histological tumor characteristics and secondary regressive changes 56. General characteristics of benign and malignant tumors 57. Mechanisms of invasion and metastatic potential, recidivism and tumor cachexia 58. General characteristics of benign epithelial tumors 59. General characteristics of malignant epithelial tumors 60. General characteristics of benign mesenchymal tumors 61. General characteristics of malignant mesenchymal tumors 62. Local and systemic tumor influence and paraneoplastic syndrome 63. Biology of tumor growth (kinetic of tumor growth, angiogenesis, heterogeneity) 64. Molecular basis of neoplasia, invasiveness and metastasis 65. Tumors of oral cavity 66. Tumors of adrenal glands 67. Hyperplasia of prostate 68. Tumors of prostate 69. Tumors of testicles 70. Nonmelanocytic skin tumors 71. Melanocytic skin tumors 72. Benign bone, cartilage and joint tumors 73. Malignant bone, cartilage and joint tumors 74. CNS tumors 75. Meningeal tumors and tumors of peripheral nervous system 76. Benign epithelial bronchial tumors and preinvasive bronchial lesions 77. Malignant epithelial bronchial tumors 78. Pleural tumors 79. Secondary lung tumors 80. Nasal and paranasal cavity tumors, pharyngeal and tonsil and throat tumors 81. Kidney tumors 82. Urinary bladder tumors 83. Heart tumors 84. Blood vessels and lymph vessels tumors 85. Precancerous lesions and carcinomas of vulva 86. Glandular endometrial hyperplasia, endometriosis and adenomyosis 87. Benign and malignant tumors of vaginal portion of uterus 88. Benign and malignant tumors of body of the uterus 89. Trophoblastic epithelial tumors 90. Cysts and benign ovary tumors 91. Malignant ovary tumors 92. Dysplastic and hyperplastic breast changes 93. Breast tumors 94. Hyperplasia and thymic tumors 95. Pituitary gland and hypothalamic tumors 96. Pediatric benign tumors 97. Pediatric malignant tumors 98. Salivary gland tumors 99. Esophageal tumors 100. Precancerous gastric changes

101. Gastric tumors 102. Small intestine tumors 103. Polyps and polyposis syndromes of gastrointestinal system 104. Large intestine malignant tumors 105. Pancreatic tumors 106. Peritoneal tumors 107. Liver tumors 108. Non - Hodgkin lymphoma 109. Hodgkin disease 110. Thyroid gland tumors 111. Parathyroid glands hyperplasia and tumors 112. Stomatitis 113. Sialoadenitis 114. Esophagitis 115. Luminal changes of esophagus 116. Gastritis 117. Peptic ulcer 118. Congenital malformations of gastrointestinal tract 119. Celiac disease 120. Enteritis 121. Ileus 122. Colitis 123. Appendicitis 124. Pancreatic cystic fibrosis 125. Pancreatitis 126. Peritonitis and foreign material in peritoneal sac 127. Liver necrosis 128. Circulatory disturbances of the liver 129. Acute viral hepatitis 130. Liver abscess 131. Alcoholic liver disease 132. Chronic hepatitis 133. Cholestasis 134. Liver cirrhosis 135. Cholelithiasis 136. Cholecystitis 137. Lymphadenitis 138. Thyreoiditis 139. Goiter 140. Basedow (Graves) disease 141. Diabetes mellitus 142. Hyper and hypo function of adrenal glands 143. Developmental anomalies of kidney and urinary passages 144. Glomerulonephritis 145. Interstitial nephritis 146. Urolithiasis 147. Vascular changes in the kidneys 148. Kidney insufficiency 149. Urinary bladder inflammations 150. Prostatitis 151. Testicular inflammations 152. Noninfectious skin diseases

153. Purulent skin inflammations 154. Viral skin inflammations 155. Special skin diseases (psoriasis, pemphigus, lupus erythematosus) 156. Skin vasculitis and panniculitis 157. Nonspecific bone, cartilage and joint inflammations 158. Specific bone, cartilage and joint inflammations 159. Osteoporosis 160. Metabolic bone diseases 161. Paget bone disease 162. Degenerative joint disease (osteoarthritis) 163. Metabolic joint disease (gout) 164. Inflammations of the uterus 165. Inflammations, erosions and pseudoerosions of cervical part of uterus 166. Adnexal nonspecific and specific inflammations (ovaries and uterine tubes) 167. Mastitis 168. Diseases of white and red spleen pulp 169. Increased intracranial pressure 170. Cerebral edema 171. Hydrocephalus 172. Ischemic brain lesions 173. Intracranial hemorrhage 174. Infectious meningeal diseases 175. Demyelinisating CNS diseases 176. Neurodegenerative diseases of cortical part of the brain, of basal ganglia and brain stem 177. Peripheral nerves pathology 178. Primary muscle diseases 179. Inflammations of nose, paranasal sinuses, pharynx and tonsils 180. Inflammations of throat, bronchi and bronchioles 181. Bronchial asthma 182. Bronchial luminal changes 183. Pulmonary hypertension 184. Pulmonary atelectasis 185. Pulmonary emphysema 186. Adult respiratory distress syndrome 187. Neonatal respiratory distress syndrome 188. Lobar pneumonia 189. Bronchopneumonia 190. Pulmonary abscesses and gangrenes 191. Interstitial pneumonia 192. Fungal and parasitic pulmonary diseases 193. Primary pulmonary tuberculosis 194. Post-primary pulmonary tuberculosis 195. Pulmonary fibrosis 196. Pneumoconiosis 197. Pleuritis and foreign material in pleural cavity 198. Ischemic heart disease 199. Hypertensive heart disease 200. Rheumatic heart disease 201. Infectious and noninfectious endocarditis 202. Chronic cardiac valves diseases

203. Cardiomyopathy 204. Myocarditis 205. Congenital heart diseases 206. Pericardial diseases 207. Atherosclerosis 208. Hypertensive arterial changes 209. Vasculitis 210. Aneurysms 211. Vein diseases For oral exam students will get 4 questions, one from each (color) group.

BASIC BOOKS :

• PATHOLOGY - Robins • MACROSCOPIC ATLAS - ROBINS

• A PRACTICAL HANDBOOK OF PATHOLOGICAL HISTOLOGY for medical students

- Živka Eri, Faculty of Medicine, Novi Sad

• HISTOLOGICAL EXERCISES ON CD - Eri Zivka, Faculty of Medicine, Novi Sad

• A PRACTICAL HANDBOOK OF MACROSCOPIC EXAMINATION IN PATHOLOGY-

Milana Panjković (it is going to be published until summer semmester) IV. FINAL EXAM PRE-EXAM STUDENT ACTIVITIES Continuous verification and evaluation of the pre-exam activities of students include: - Regular attendance at lectures, - Regular attendance and active participation in exercises / review and evaluation of knowledge on each exercise, - Attendance at autopsies, - One colloquium for microscopic preparations, and one colloquium for macroscopic preparations at the end of the school year in the last two weeks of summer semester, - Theoretical test at the end of the summer semester. 1.1. Regular attendance at lectures The presence to the theoretical lectures is the statutory obligation.

1.2. EXERCISES

Students regularly attend and actively participate in the histological and macroscopic exercises with checking and obtaining points, or evaluation of knowledge on each exercise.

During the two last week of practical training at the end of the summer semester, the student MUST take the colloquiums from microscopic and macroscopic exercises. At the practical part of the exam, the student must have a minimum of theoretical knowledge which can explain the lesions recognized on microscopic slides and museum preparations.

During the last two exercises in the summer semester students take the practical exams that include: - colloquium for microscopic preparations, which includes diagnosis and description of three slides (which then have to be explained orally to the teacher). For passing exam, 2 slides have to be correctly described. - colloquium for museum gross (macroscopic) preparations comprising 2 macroscopic description that also have to be explained orally to the teacher. For passing exam, 2 preparations have to be correctly described.

The teacher has the right to ask the theoretical questions related to the pathological changes present in the preparations.

If student does not pass the preliminary exams, student will take the practical exam during the official examination period starting from the June exam period of the current year.

Both microscopic and gross practical colloquia are graded (6 to 10), and signed in the index. Passed practical exam is valid forever!

1.3. THEORETICAL COLLOQUIUM

Students must take the theoretical test at the end of summer semester from General and Special Pathology.

The theoretical test is eliminatory and has 40 questions. The minimum number of points for passing is 60% correct answers which carries 24 points. Test is also graded 6 to 10.

Passed test is valid forever! The test results are published on the same day on official website of Medical faculty. It is

possible to see the test after published results, at time and place that will be published with test results.

Passed theoretical test and two practical exams (Microscope and Macroscopic) are a prerequisite for taking the final oral exam.

Students who did not take those exams or did not pass in pre-examination period will have the opportunity to pass them during the regular examination periods starting from the June period of the current school year. Place and time of the tests will be at the website of the Medical faculty and the notice board at the Department of Pathology and Histology at the first floor of the Medical Faculty in Novi Sad. 2. FINAL ORAL EXAM

The student may take the oral part of the exam after the certified VI semester, obtaining the signatures from teachers in the index and passing all partial components within the pre-examination student activities.

Student can not take the final oral exam unless he did not pass all three partial exams (test, macroscope, microscope).

Oral examination shall be provided in examination periods according to the Statute of the School of Medicine Department of the Faculty of publication at the beginning of the school year and in line with the adopted Ordinance on examination at the Medical School.

Final oral exam from lectures consists of four questions, and two questions are from the General Pathology and two questions are from the special pathology. In case of constrained assessment, examiners have discretion to set additional questions from the overall curriculum.

After theoretical test, students must sign on the list enrolled at the hall of Histology and Pathology Department, and select the desired date of examination. Department will try to meet the wishes of students (in the range of +/- 2 to 3 days).

For the oral exam, students 'electe teachers' by drawing cards with the names of examiners randomly on the day of the exam.

Department of Pathology has a common criterion that a candidate must give a positive answer to each of the four theoretical questions for a positive assessment.

Taking the test, preliminary exams from the practical part of teaching and / or oral exam have to be confirmed 72 hours (Saturday and Sunday do not count) before by leaving signatures to the Secretary of the Department (first floor of the Medical faculty - Department of Pathology and Histology).

Time and place of the test and the theoretical exam stands out in a timely manner on the bulletin board of the Department for Pathology and Histology and on the website of the Medicine Faculty specifically for each examination period.