04/18/23

2009-08012-01

Enzymes for CIPI & I Applications

CIP/Membrane cleaning

NOVOZYMES PRESENTATION2 04/18/23

Process industry Cleaning in Place = CIP Organic deposit found in pipes, tanks and industrial equipment

are efficiently removed by enzymes CIPzyme for dairy membrane cleaning Celluclean for Brewing membrane cleaning Lipex, Flavourzyme, Pectinex Ultra SP-L for Food processing lines

Improved cleaning targeting specific organic problem soils with the right enzyme

Extended lifetime of equipment (e.g. membranes, pipes, tanks) by cleaning under mild conditions

Higher productivity Reduced downtime Increased filtration flowrates

Less chemicals and process aids (e.g. kieselgühr) Lower temperatures and energy consumption Reduction of water consumption More environmental friendly cleaning procedure Less risk of accidents to people

Benefits of enzymes in Food & Beverage CIP

NOVOZYMES PRESENTATION3 04/18/23

Removal of washing solution and residual enzymes is critical

Novozymes offer a rapid test kit for lipase detection Inactivation and validation procedure to be developed

by Detergent formulator or end-user Novozymes assume no liability for problems with

residual enzyme activity in process equipment No use of enzymes on open hard surfaces without

case by case safety approval

CIP/Membrane cleaning

NOVOZYMES PRESENTATION4 04/18/23

NZ positioning in I&I – Dairy membrane cleaning and CIP

NOVOZYMES PRESENTATION5 04/18/23

Novozymes preferred products

Selling pointsCompetitor

productNZ product

discriminator

CIPzymeSynergistic effect of Lipase and Protease for Dairy membrane cleaning

Caustic and acid

Superior removal of problematic lipid-protein fouling and residues in a.o. heatexchangers

NZ positioning in I&I – Brewing membrane filtration, Food processing cleaning

NOVOZYMES PRESENTATION6 04/18/23

Novozymes preferred products

Selling pointsCompetitor

productNZ product

discriminator

Celluclean

Betaglucan removal under mild conditions gives superior Brewing membrane filtration

Traditional filtration with Kieselgühr?

Eliminates health risk of kieselgühr

Targeted cleaning

Equipment lifetime

Flavourzyme

Pectinex Ultra SP-L

Lipex

Higher degree of protein hydrolysis under mildly acidic conditions

CIP food industry (marmelade, juice production, cider)

Fat degradation and in-depth removal

Acid wash

Detergents

Unique solution in selected case

Lifetime of expensive equipment

CIPzyme offers far superior cleaning than single enzymes

NOVOZYMES PRESENTATION7 04/18/23

CIPZYME IS A COMBINED PRODUCT,

CONTAINING PROTEASE

AND LIPASE, WHICH

CREATE A SYNERGISTIC

EFFECT ON THE

HYDROLYTIC EFFECTSHYDROLYSES ON HOMOGENIZED MILK (S=0.4% DRY MATTER)

ENZYMES USED ARE PROTEASES, LIPASES AND CIPZYMETEST METHOD: PH-STAT AT 50ºC, PH=8

Minutes

Hydro

lyti

c act

ivit

y

CIPzyme is a product optimized for the use in dairies and an enzyme preparation with proteolytic and lipolytic activities

Benefits of CIPzyme: Maximizing equipment utilization Improved and targeted cleaning Extended equipment lifetime Lower consumption of chemicals Lower temperatures and lower energy

consumption Reduction of the water consumption More environmental friendly cleaning

procedure Less risk of people related accidents

Benefits of CIPzyme

NOVOZYMES PRESENTATION8 04/18/23