prof. sarita gupta, phd. msc. bsc

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Prof. Sarita Gupta Bio-Sketch 1 Prof. Sarita Gupta, PhD. MSc. BSc. Molecular Endocrinology and Stem Cell Research Lab, Department of Biochemistry, Faculty of Science, The M. S. University of Baroda, Vadodara. Tel no: +91-9426319494 (Mob). Office no: +91-265-2794544. Email: [email protected] Name: Sarita Gupta Date of Joining: 1 st January 1987 Current Position: Professor, Dept. of Biochemistry, M. S. U., Vadodara, INDIA Coordinator: DBT ILSPARE Project, a DBT sponsored inter-disciplinary life science programme Coordinator: 5 year Integrated M.Sc. Course on Cell and Molecular Biology Academic Qualifications Degree Field of Specialization Institution Year Ph.D. Biochemistry Nagpur University 1984 M.Sc. Biochemistry Nagpur University 1980 B.Sc. Chem, Zoo, Bot Nagpur University 1978 Teaching Experience -- 28 years of experience. Designation/Title Organization Dates (From To) Head Department of Biochemistry,MSU November 2013 onwards Head Department of Biochemistry,MSU July 2009- July 2011 Professor Department of Biochemistry,MSU Sept -2006 Onwards Associate professor Department of Biochemistry,MSU 1998 - 2006 Assistant Professor Department of Biochemistry,MSU 1987-1998

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Prof. Sarita Gupta Bio-Sketch

1

Prof. Sarita Gupta, PhD. MSc. BSc.

Molecular Endocrinology and Stem Cell Research

Lab,

Department of Biochemistry,

Faculty of Science,

The M. S. University of Baroda, Vadodara.

Tel no: +91-9426319494 (Mob).

Office no: +91-265-2794544.

Email: [email protected]

Name: Sarita Gupta

Date of Joining: 1st January 1987

Current Position: Professor, Dept. of Biochemistry,

M. S. U., Vadodara, INDIA

Coordinator: DBT ILSPARE Project, a DBT sponsored inter-disciplinary life science

programme

Coordinator: 5 year Integrated M.Sc. Course on Cell and Molecular Biology

Academic Qualifications

Degree Field of Specialization Institution Year

Ph.D. Biochemistry Nagpur University 1984

M.Sc. Biochemistry Nagpur University 1980

B.Sc. Chem, Zoo, Bot Nagpur University 1978

Teaching Experience -- 28 years of experience.

Designation/Title Organization Dates

(From – To)

Head Department of Biochemistry,MSU November 2013

onwards

Head Department of Biochemistry,MSU July 2009- July

2011

Professor Department of Biochemistry,MSU Sept -2006

Onwards

Associate professor Department of Biochemistry,MSU 1998 - 2006

Assistant Professor Department of Biochemistry,MSU 1987-1998

Latest Photo

graph

Prof. Sarita Gupta Bio-Sketch

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Assistant Professor LAD college Nagpur University . 1984-1985

Teaching Interests- I am responsible for teaching Clinical biochemistry, Physiology,

Cell-biology, and Molecular Endocrinology at the Post-Graduate level at the

Department of Biochemistry since last 26 years. In addition, I have contributed to the

annual updates and revision in the Post-Graduate syllabus as an active committee

member. In fact I played major role in starting M.Sc. programme in Medical

Biotechnology (2007). Besides, I have been actively engaged in delivering lectures in

other universities, recently invited as UGC Visiting Professor at Dept. of Biochemistry,

Nagpur University, Nagpur. In addition, I have incorporated several innovative ways

of conducting case-study methodology so as to get an in-depth understanding and also

delivered lectures for school children under INSPIRE programme.

Research Experience- 30years

(M. Sc. / M. Phil /Ph. D. / Post-doctoral Research)

Degree/Dissertation Awarded Working

Ph. D. 09 05

M. Phil. Nil

M.Sc. dissertations ~ 100 04

Awards/ Fellowships/ Memberships:

Indo-Canadian Shastri foundation travel award – for visiting Institute of cardiovascular

sciences, university of Manitoba, Winnipeg and for visiting Laval University Quebec for

collaborative research Oct 2011

Certificate of Appreciation- for outstandingly procuring DBT-IPLS Project , 2011

Nominated –for Prof G. N. Ramachandran Gold Medal award for Excellence in Biological

Sciences & Technology – 2010, 2011.

Nominated -for Rayan International Award in the field of Reproductive biomedicine and

stem cell research in 2007.

Travel award for attending 8th annual meeting of International Society for Stem Cell

Research to attend annual meeting at San Francisco June 2010 .

Visiting scientist under - Mutual exchange programme between MSU and SUNY

Buffalo USA.-Underwent training in Cell Biology and Molecular Biology techniques

Prof. Sarita Gupta Bio-Sketch

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specially for ongoing research at Biochemistry Department, School of Medicine and

Biomedical Sciences at State University of New York, Buffalo NY. September to

December, 1999.

Memberships: International society of stem cell research, Society of Biological chemistry,

Society of reproductive & Comparative Endocrinology

Contribution in conducting Academic Programmes:

1. Invited as an expert in UGC major and minor research project committee, Nov &Dec

2011, Nov 2012.

2. Invited as an expert in DBT task force meeting for builder program, July 2011

Organization of symposium/workshop:

1. Workshop on basic cell culture and stem cell techniques. as an Organizer , Dept. of

Biochemistry, The MS university of Braoda from 28th feb to 3rd march. 2012.

2. Conducted 3rd PTMF annual meeting and 2nd visiting scientist programme as a co-

chairperson in Dec. 2011.

3. Conducted XIIth Gujarat science Congress as a co-chairperson 26th Feb. 2012

4. Workshop on “ Analysis of cell death in mammalian cells” conducted by Department

of Biochemistry, MS University and Laval University, Faculty of medicine, Quebec,

Canada.21st-24th Dec,2010

5. National level workshop as coordinator on Molecular biology techniques in disease

diagnosis.

6. Refresher Course in Advances in Biochemistry.

National and International Lectures/invited speaker:

1. Invited lecture on ‘Research proposal writing’ at teachers refresher seminar at Faculty

of Technology, The M. S. University of Baroda, 3rd March, 2014.

2. Scientific talk on ‘Nutrigenomics: Understanding the efficacy of herbal bioactive

compounds in amelioration of Type I and Type II diabetes’ organized by Sardar Patel

University, Vidyanagar at a national conference Nutrigenomics : A Promising Tool for

Combating Chronic Diseases on 5th February 2014.

3. Scientific talk on ‘Perspective of Stem Cell Research & Therapy in Diabetes’ at the

international conference on human genetics and 39th annual meeting of the Indian

society of human genetics organized by Institute of human genetics, Ahmedabad on

25th January 2014.

4. Lecture on ‘Career Opportunities in Science’ organized by DBT Inspire, October 2013.

Prof. Sarita Gupta Bio-Sketch

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5. Lecture on ‘Exciting Discoveries in Science’ organized by DBT Inspire, September

2013.

6. Lecture on ‘Novel bioactive compounds (Neutraceuticals) potentiating stem cell

differentiation into insulin producing cells-An approach of regenerative medicine in

treatment of diabetes mellitus’ at the National conference on ‘Diabetes and its

complications: Search for Prevention and Cure’ at Nirma University, Ahmedabad on

7th September, 2013.

7. Interactive session at Shastri Indo-Canadian institute on collaborative research on The

M. S. University and Laval University, Canada on ‘Role of PARP-1 implicated in islet

neogenesis and adipogenesis from stem/progenitors using novel bioactive compounds’

on 2nd June, 2013.

8. Lecture on ‘Stem cell hype and hope’ at Rotary club, Vadodara- 5th April, 2013.

9. Lecture on ‘Cancer: A Stem cells Disease’ at a one day Symposium on National Science

Day at GCRI, Ahmedabad- 28th Feb, 2013.

10. Lecture on ‘Novel Therapeutic Approach in Diabetes: Insight in Cell Therapy and

Neutraceuticals’ at AICTE-Sponsored National Conference on ‘Approaches in Drug

Discovery’ at the Faculty of Technology and Engineering, The Maharaja Sayajirao

University of Baroda, Vadodara- 27th Feb, 2013.

11. Lecture on Islet Neogenesis from Stem cells- potential and mechanism of SGL-1 at

SREBC- 30th Jan to 1st Feb, 2012, Udaipur.

12. Lecture on Cellular and molecular mechanism of endocrine disruptors: Implications in

female reproductive physiology in a national Symposium on BIORESEARCH,

BIOETHICS AND ENVIRONMENT held at LAD college Nagpur, December 2011.

13. Lecture on ‘Cardioprotective and islet neogenic potential of Enicostemma littorale’ in

Winnipeg Heart International Conference at Winnipeg, Canada, October 13-16, 2011

14. Lecture on Interdisciplinary approach “University perspective workshop on scientific

writing and collaborative research” organized by GSBTM and IIAR. 4th February

2011.

15. Lecture on “Carrier Opportunities in Biological sciences- Under INSPIRE programme

of DST for school children”. Organized by DST –INSPIRE Programme and MSU,

Baroda. Nov 2010.

16. Lecture on “Cell and Islet Therapy: Newer Avenues In Diabetes Therapy” in a national

conference organized by Nirma University, Ahmedabad , March-2010.

17. Lecture on “Cell therapy: A new vistas for Diabetes therapeutics” in “Workshop on

Immunological , Molecular and Animal cell culture Techniques” organized by CIIMS

, Nagpur ,December 4th-24th, 2008.

18. Lecture series on “ Cell Signalling” conducted by Department of Biochemistry,

University of Nagpur Dec, 2010 as UGC resource person for 5 days (10 lectures).

International conferences:

1. International Conference on Diabetes and its complications as Chairperson at Charusat

University, Changa, Gujarat, on 18th to 20th January 2013.

2. International Conference of SREBC at MLS University Udaipur on 30th jan. to 1st feb.,

2012.

Prof. Sarita Gupta Bio-Sketch

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3. 4th world congress of International Academy of Cardiovascular Sciences, “Bridging the

Gap: Basic sciences & Clinical Practice” Organized by M. S. University of Baroda,

Vadodara. Feb, 2011

4. International conference on MOLECULAR MEDICINE, organized by Charotar

University of Science and Technology, changa, Gujarat. Jan-2011

5. 7th annual meeting organized by International Society for Stem Cell Research, 7th to

11th July 2009, Barcelona, SPAIN.

6. International Symposium on Advances in molecular medicine and clinical

implications organized by Reliance Life Sciences, Mumbai, Jan 24th-25th 2009.

7. ADNAT, International Conference for Adult Stem Cells, organized by Centre for

Cellular and Molecular Biology, Hyderabad, India. 21-24 February, 2008.

8. International Symposium on Preventive and predictive molecular diagnostics

organized by Reliance Life Sciences, Mumbai, Jan 21th-22th 2006.

9. International Conference on Toxicology, Toxico-genomics and Occupational Health,

organized by Jiwaji University, Gwalior (MP) Oct. 2006.

10. International symposium on “Molecular Medicine” organized by M.S. University of

Baroda, The State University of New York (SUNY) at Buffalo, NY, USA and Sun

Pharmaceutical Industries Ltd., at Baroda, Jan. 2000.

11. 1st International symposium on “Recent advances in Molecular Biology, allergy and

immunology”. Organized by MSU, Baroda and SUNY, Buffalo, held at Baroda, Sep.

2000.

National conferences:

1. National Conference on Diabetes and its Complications: search for prevention and cure

at Nirma University, Ahmedabad on 7th September 2013.

2. National Conference on approaches in drug discovery at the pharmacy dept. The M. S.

University of Baroda, Vadodara on 27th feb, 2013.

3. Gujarat Science Congress 2012, on 26th Feb, organized by MS university Baroda.

4. National Conference and 30th Annual Symposium of the SRBCE on Novel Aspects

and Emerging Trends in Reproduction and Endocrinology, organized by Dept. of

Zoology M.S. University, Udaipur (Raj.) from 30th Jan to 1st Feb, 2012

5. Interdisciplinary approach “University perspective workshop on scientific writing and

collaborative research” organized by GSBTM and IIAR. 4th February 2011.

6. A symposium on “Emerging trends in Cell Biology” organized by School of biological

sciences & Biotechnology, IIAR, held at Gandhinagar, April,2010.

Prof. Sarita Gupta Bio-Sketch

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7. Brain storming session on clinical research facility to develop stem cell technologies

and regenerative medicine organized by NIRRH, Mumbai jan 15th-16th 2010 .

8. CME in immunology organized by Deptt. Of Biochemistry, Faculty of science, MS

university, baroda on 27th -28th nov 2009

9. Diabetes research meeting organized by national center for cell sciences Pune India,

held on july 15th-16th 2008.

10. ‘National seminar on New Horizons in. Organized by N. V. Patel college of Pure &

Applied Sciences, S.P.U, Vidyanagar, Sep. 2007.

11. National symposium on cancer and apoptosis; organized by department of

biochemistry, 2007

12. National Symposium on ‘Recent Advances in Reproduction, Endocrinology and

Development and, associated Disorders’ organized by UGC-DSA. Jan. 2006.

13. National seminar on „Humanity’s Heritage: Our Genome and Stem Cells’ held by Dept.

of Microbiology and Biochemistry, M. S. University of Baroda, Oct, 2006.

14. National seminar on ‘Trends in Biochemical Sciences’ organized Department of

Biochemistry, M. S. University of Baroda, Vadodara March 2005.

15. Indian Science Academy Sponsored seminar on „Modern Biology: Facets and

Prospects’, Organized by Department of Biochemistry, The M.S. University of Baroda

and Tata Institute of Fundamental Research, Mumbai, at Baroda, Oct. 2005.

16. YIM meeting Hyderabad 8-10 February 2014.

Research interests: Diabetes, Stem cell research, Clinical Biochemistry, Molecular

Endocrinology.

Molecular mechanism involved in stem cell differentiation into neo-islets formation and

adipogenesis using novel phyto-pharmaceuticals isolated from Enicostemma littorale:

My research is focused on exploring the natural and medicinal properties of one Indian plant

Enicostemma littorale, which has shown by our studies to have antioxidant, antidiabetic,

hypoglycaemic, hypolipidemic and islet neogenic activity (10 Papers). It also discovered to

possess anti-malarial activity. We have identified several novel biomolecules from

Enicostemma Littorale and investigated in vitro islet neogenic from adult progenitor cells and

anti-adipogenic potential, which can be exploited as an attractive option for the treatment of

diabetes. (Gupta et al., IJIB, 2010 and Gupta and Bhonde, Indian patent, 2009). SGL-1 was

characterized to have islet neogenic potential from stem/progenitors (Dadheech et. al., 2013)

and Swertiamarin, an active lead from Enicostemma littorale regulates insulin sensitive

peripheral tissue gene expression by targeting PPAR-γ & improves insulin sensitivity in TIIDM

(Patel et al.,2013). Also, our team in collaboration with (Laval University, Canada) working to

understand molecular mechanism and role of Poly (ADP-ribose) Polymerase enzyme in islet-

neogenesis and adipogenesis from stem precursors.

Molecular mechanism of Insulin resistance:

Emphasis of the work was to elucidate the effect across the HPG axis with respect to steroid

biosynthesis and steroid metabolism and granulose cell as model (15 papers) Present focus

Prof. Sarita Gupta Bio-Sketch

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is to identify the cellular and molecular mechanisms that are responsible for relaying the actions

of gonadotropins, growth factors, and cytokines in granulose cells with specific reference to

insulin resistance.

We have recently started exploring paradigm in type III diabetes i.e. insulin resistance in brain.

Here we are trying to understand the relation between brain insulin resistance and its effect on

cognitive functions and neurogenesis.

Molecular mechanism of etiopathogenesis of BPH:

Another focus is, to elucidate molecular mechanism of pathogenesis of Benign prostatic

hyperplasia (BPH), and to understand the role of stem cell in the in the disease condition since

endocrine imbalance plays key role in prostate cancer and BPH. We are also doing SNP

analysis of patients especially for AR and ER genes.

Research Projects: (Completed and Ongoing)

Sr. No. Title of the project Financing Agency Duration

1 Ascorbic acid synthesis in human

placenta and fetus

M.S. University of

Baroda

1989 – 1990

2 Studies on Zinc status of progeny

of mothers exposed to lead in

relation to undernutrition.

UGC, New Delhi

1991 – 1992

3 Screening of population for lead

exposure

M.S. University of

Baroda

1992 – 1993

4 Studies on simultaneous exposure

of lead and cadmium in relation to

essential mineral status

UGC, New Delhi

1995 – 1996

5 Clinical evaluation of

Enicostemma littorale A natural

herb.

DST, New Delhi 1997 – 1999

6 Studies on low level

simultaneous exposure of lead and

cadmium on endocrine status in

nonpregnant, pregnant and

lactating female rats.

UGC, New Delhi

1998 – 2001

Prof. Sarita Gupta Bio-Sketch

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7 Systematic studies to identify,

evaluate and understand

antidiabetic potential of a natural

herb – Enicostemma littorale.

DST, New Delhi

2004-2007.

8 Evaluation of Islet neogeneic

potential of enicostemma littorale

blume

DBT-New Delhi

Stem cell Task force

2007-2011

9 Association of Single Nucleotide

Polymorphic candidate genes

with Benign Prostatic

Hyperplasia and Prostate cancer.”

UGC 2011-2014

10 Interdisciplinary life science

programme as– - coordinator

DBT ,New Delhi 2010-2015

11 Poly (ADP-ribose) polymerase-1

and pancreatic islet differentiation

from progenitors: Implications in

Diabetes.

DBT Basic, New Delhi 2012-2015

12 Role of brain insulin receptor in

phenotypic plasticity of white

matter progenitor cells.

DBT, India 2013-2016

Publications: Since 2000 our team has been contributing number of publications with high

citations. Total 51 papers we have published since 1987 till 2014. 50 are in reputed journals

and 1 in proceedings. 15 publications are cited 154 times out of which EL work articles were

cited 113 times and reproductive dysfunctions work was cited 41 times. With all publications,

i have a current H index of 14.

List of publications (Research Papers/ books):

Sr. Authors Title of Publication Journal with I.F.

1 Akhilesh Prajapati

, Sharad Gupta

, Ramesh Bhonde

and Sarita Gupta

Pluripotent Stem Cell

within the Prostate

could be Responsible

Stem Cell research

and Therapy

I.F. 5.88

Feb

2014

Volume 4;

Issue 1

Prof. Sarita Gupta Bio-Sketch

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for Benign Prostate

Hyperplasia in Human

2 Chitra

Ankleshwaria, Mehul

Mistri, Ashish

Bavdekar, Mamta

Muranjan,Usha

Dave, Parag

Tamhankar, Varun

Khanna, Eresha

Jasinge, Sheela

Nampoothiri, Suresh

Edayankara

Kadangot, Frenny

Sheth, Sarita

Gupta and Jayesh Sheth

Novel mutations in the

glucocerebrosidase gene of

Indian patients with

Gaucher disease.

Journal of Human

Genetics (NPG).

I.F. 2.36

Feb

2014

Volume 5

3 Chitra

Ankleshwaria, Jayesh

Sheth, Mehul

Mistri, Ashish

Bavdekar, Sheela

Nampoothiri,

SaritaGupta and Frenny

Sheth

Identification of novel

mutations in

glucocerebrosidase (GBA)

gene in Indian patients

with gaucher disease (GD)

Molecular

Cytogenetics

I.F. 2.36

Jan

2014

Volume 7-

S1-P52

4 Mehul Mistri,

Chaitanya Datar

, Frenny Sheth

, Sarita Gupta

, Jayesh Sheth

Identification of Novel

Mutations in HEXA

Gene in Children

Affected with Tay-

Sachs Disease from

India. (poster

presentation)

Molecular

Cytogenetics

I.F. 2.36

Jan

2014

Volume 7-

S1-P53

5 Jayesh Sheth

, Mehul Mistri, Frenny

Sheth

, Sarita Gupta

Prenatal diagnosis of

Tay-Sachs disease: our

institutional

experience. (Poster

presentation)

Molecular

Cytogenetics

I.F. 2.36

Jan

2014

Volume 7-

S1-P124

6 Sarita Gupta Perspective of stem cell

research & therapy in

diabetes (Abstract).

Molecular

Cytogenetics

I.F. 2.36

Jan

2014

Volume 7-

S1-I61

7 Akhilesh Prajapati,

Sharad Gupta, Bhavesh

Mistry, and Sarita

Gupta

Review: Prostate Stem

Cells in the

Development of

BioMed Research

International.

2013 Volume

2013

(2013),

Article ID

Prof. Sarita Gupta Bio-Sketch

10

Benign Prostate

Hyperplasia and

Prostate Cancer:

Emerging Role and

Concepts.

I.F. 2.88 107954, 10

pages

8 Mohammad Mahboob

Kanafi,

YajamanBajjappa

Rajeshwari, Sarita

Gupta, Nidheesh

Dadheech, PrabhaNair,

Pawan Kumar Gupta

and Ramesh

RamchandraBhonde.

Transplantation of islet

like cell clusters

derived from human

dental pulp stem cells

restores

normoglycemia in

diabetic mice

Cytotherapy

I.F. 3.27

2013 Volume 15,

Issue 10,

October

2013, Pages

1228–1236

9 Tushar P. Patel, Sanket

Soni , Pankti Parikh,

Ragitha Chruvattil and

Sarita Gupta

Swertiamarin : An

active lead from

Enicostemma littorale

regulates Hepatic and

Adipose tissue gene

expression by targeting

PPAR-γ & improves

insulin sensitivity in

experimental NIDDM

Rat model

Evidence Based

Complementary and

Alternative Medicine

I.F. 4.7

2013 Volume

2013

(2013),

Article ID

358673, 11

pages

10 Rajani Giridhar, Riyaj

S. Tamboli, Dhaval G.

Prajapati, Sanket Soni,

Sarita Gupta, M. R.

Yadav

Synthesis of novel 4,6-

diaryl-2-

aminopyrimidines as

potential

antiplasmodial agents

Medical Chemistry

Research

I.F. 1.6

2013 July 2013,

Volume 22,

Issue 7

11 Yusuf, B.,

Gopurappilly, R.,

Dadheech, N., Gupta,

S., Bhonde, R. and Pal,

R

Embryonic fibroblasts

represent a connecting

link between

mesenchymal and

embryonic stem cells

Development, growth

and differentiation

I.F. 2.39

2013 Dev

Growth

Differ.

2013

Apr;55(3):3

30-40

12 Dadheech N, Soni S,

Srivastava A,

Dadheech S,

Gopurappilly R,

Bhonde RR and Gupta

S

A Small Molecule

Swertisin from

Enicostemma littorale

Differentiates NIH3T3

cells into Islet like

Clusters and Restores

Normoglycemia upon

Evidence Based

Complementary and

Alternative Medicine

I.F. 4.7

2013 Volume

2013

(2013),

Article ID

280392

Prof. Sarita Gupta Bio-Sketch

11

Transplantation in

Diabetic Balb/c Mice

13 Dadheech N,

Srivastava A, Belani

M, Gupta S, Pal R,

Bhonde RR, Srivastava

AS, Gupta S

Basal Expression of

Pluripotency

Associated Genes Can

Contribute to Stemness

Property and

Differentiation

Potential.

Stem Cells and

Development

I.F. 4.67

2013 Stem Cells

Dev. 2013

Jun

15;22(12):1

802-17

14 Pandya C, Prajapati A,

Bhan A, Khan A, Pillai

P, Gupta S and Gupta S

Association of

Cadmium and lead

with antioxidant status

and incidence of

benign prostatic

hyperplasia in patients

of western India

Biological Trace

Element Research

I.F. 1.3

2013 Biol Trace

Elem Res.

2013

Jun;152(3):

316-26.

15 Prakash pillai, Chirayu

Pandya, Bhatt Niraj,

Gupta Sarita

Biochemical and

reproductive effect of

gestational/lactational

exposure to lead and

cadmium with respect

to testicular

steroidogenesis,

antioxidant system,

endogenous sex steroid

and cauda epididymal

functions.

Andrologia

I.F.1.9

2012 44(2):92-

101

16 Pandya C, Pillai P,

Nampoothiri LP, Bhatt

N, Gupta S, Gupta S

Effect of lead and

cadmium co-exposure

on testicular steroid

metabolism and

antioxidant system of

adult male rats

Andrologia

I.F. 1.9

2012 44 Suppl

1:813-22

17 Bhatt N, Chavda M,

Desai D, Jhalawadiya

R, Patel V, Burade V,

Sharma A, Singal P and

Gupta SS

Cardioprotective and

anti-hypertensive

effects of EL blume

extract in fructose fed

rats

Can. J. physiol.

pharmocol.

I.F. 1.7

2012 90. 1065-

1073

Prof. Sarita Gupta Bio-Sketch

12

18 Mistry M, Tamhankar

PM, sheth F, Shangavi

D, Kondurkar P, Patil

S,Idicula-Thomas S,

Gupta S, Sheth J.

Identification of novel

mutation inHEXA gene

in children affected

with Tay-sach disease

from india

PloS One

I.F. 4.2

2012 7(6)

19 Niraj M. Bhatt , Kinjal

Chauhan , Sharad

Gupta , Prakash Pillai ,

Chirayu Pandya , Jyoti

V. Thaikoottathil and

Sarita S. Gupta.

Protective Effect of

Enicostemma littorale

Blume Methanolic Extract

on Gentamicin-Induced

Nephrotoxicity in Rats.

American Journal of

Infectious Diseases

I.F. 1.3

2011 Volume 7,

Issue 4,

Pages 83-

90.

20 Prakash P Pillai,

Chirayu D Pandya and

Sarita S Gupta

Book edited by: Prof. Dr.

Volodymyr I. Lushchak;

Co-editor: Prof. Dr.

Oksana Stoliar

Oxidative Stress /

Book 3; ISBN 979-

953-307-749-8;

2010 In press

21 Prakash Pillai, Chirayu

Pandya, Sharad Gupta

and Sarita Gupta.

Biochemical and molecular

effects of gestational and

lactational co-exposure to

lead and cadmium on

ovarian steroidogenesis are

associated with oxidative

stress in F1 generation rats.

Journal of

Biochemical and

Molecular

Toxicology

I.F. 1.56

2010 24(6):

22 Chirayu D. Pandya,

Prakash P. Pillai and

Sarita S. Gupta

Lead and Cadmium Co-

exposure Mediated Toxic

Insults on Hepatic Steroid

Metabolism and

Antioxidant System of

Adult Male Rats

Biological Trace

Element Research,

Biol Trace Elem Res.

1.37

2010 134(3):307-

17

23 Sarita Gupta, Nidheesh

dadheech, Anubha

singh,Sanket soni and

R.R. bonde.

Enicostemma littorale: a

new therapeutic target for

islet neogenesis.

International Journal

of Integrative

Biology

2010 9(1):49

24 Sanket Soni and Sarita

Gupta

In vitro Anti Plasmodial

Activity of Enicostemma

littorale

American Journal of

Infectious Diseases

I.F. 1.3

2009 5 (3): 259-

262,

25 Prakash Pillai, Ritesh

Patel, Chirayu Pandya

and Sarita Gupta

Sex specific effects of

gestational and lactational

co exposure to lead and

cadmium on hepatic phase

I and phase II

xenobiotic/steroid

metabolizing enzymes and

antioxidant status.

Journal of

Biochemical and

Molecular

Toxicology

I.F. 1.596

2009 (6):419-31

Prof. Sarita Gupta Bio-Sketch

13

26 Niraj Mukundray

Bhatt, Suparna Barua

and Sarita Gupta

Protective Effect of

Enicostemma littorale

Blume on Rat Model of

Diabetic Neuropathy

American Journal of

Infectious Diseases

I.F. 1.3

2009 5 (2): 106-

112

27 Laxmipriya P.

Nampoothiri, Sarita

Gupta

Biochemical effects of

gestational coexposure to

lead and cadmium on

reproductive performance,

placenta, and ovary

Journal of

Biochemical and

Molecular

Toxicology

I.F. 1.596

2008 Volume 22,

337 – 344

28 Laxmipriya P.

Nampoothiri, Avnika

Agarwal and Sarita

Gupta

Effect of co-exposure to

lead and cadmium on

antioxidant status in rat

ovarian granulosa cells

Archives Toxicol.

I.F. 5.215

2007 81, 145-150

29 P.N.Laxmi Priya, &

Sarita Gupta

Simultaneous effect of

lead and cadmium on on

granulosa cells A cellular

model of ovarian toxicity

Reproductive

Toxicology

I.F. 3.94

2005 21, 179-185

30 Vihas T. Vasu, Hiren

Modi, Jyoti V.

Thaikoottathil, Sarita

Gupta

Hypoglycemic effect of a

polyherbal aqueous extract

in experimentally induced

diabetic rats

Oriental pharmacy

and experimental

medicine

2005 5:160-166

31 Vihas T. Vasu, Hiren

Modi, Jyoti V.

Thaikoottathil, Sarita

Gupta

Hypolipidaemic and

antioxidant effect of

Enicostemma littorale

Blume aqueous extract in

cholesterol fed rats

Journal of

Ethnopharmacology

I.F. 3.22

2005 101:277-

282

32 Pillai, and Sarita Gupta Antioxidant enzyme

activity and lipid

peroxidation in liver of

female rats co-exposed to

lead and cadmium: effects

of vitamin E and Mn2+

Free Radical

Research

I.F. 3.279

2005 39, 707–

712

33 Anilkumar Pillai &

Sarita Gupta

Effect of gestational and

lactational exposure to lead

and/or cadmium on

reproductive performance

and hepatic estradiol

metabolism.

Toxicology Letters

I.F. 3.145

2005 * 155, 179-

186

34 P.N.Laxmi Priya, Anil

Pillai & Sarita Gupta

Effect of simultaneous

exposure to lead and

cadmium on gonadotropin

binding and

steroidogenesis on

granulosa cells: An in vitro

study.

Indian Journal of

Experimental

Biology

I.F. 1.195

2004. Vol. 42,

143-148,

35 Vihas T. Vasu, C.

Ashwinikumar, Jyoti

Maroo, Sharad Gupta,

Sarita Gupta

Antidiabetic effect of

Enicostemma littorale

Blume aqueous extract in

newly diagnosed non-

Oriental Pharmacy

and Experimental

Medicine

2003 3: 84 – 89

Prof. Sarita Gupta Bio-Sketch

14

insulin-dependent diabetes

mellitus patients

(NIDDM): A preliminary

investigation

36 Jyoti Maroo, Arna

Ghosh, Rajni Mathur,

Vihas T. Vasu, Sarita

Gupta

Evaluation of antidiabetic

efficacy of Enicostemma

littorale methanol extract

in alloxan induced diabetic

rats.

Pharmaceutical

Biology

I.F. 1.06

2003 5: 388 –

391.

37 Jyoti Maroo, Vihas T.

Vasu, SaritaGupta

Dose dependent

hypoglycemic effect of

aqueous extract of

Enicostemma littorale

Blume in alloxan induced

diabetic rats.

Phytomedicine

I.F. 3.258

2003. 10: 196 –

199.

38 Anil Pillai, Laxmipriya,

Sarita Gupta

Effects of combined

exposure to lead and

cadmium on hypothalamic-

pituitary axis function in

proestrous rats.

Food and Chemical

Toxicology

I.F. 3.215

2003 41: 379 –

384

39 Vihas T. Vasu, Jyoti

Maroo, C.

Ashwinikumar, Sharad

Gupta, Kantaben H.

Patel, Sarita Gupta

Antioxidative and

antihyperglycemic action

of Enicostemma littorale

Blume in diabetes mellitus.

In: Proceedings of

IInd International

symposium of

Molecular Medicine

M.S. University of

Baroda, Gujarat,

India.

2002 held on 20

– 23rd Jan

40 Anil Pillai, Laxmipriya,

Ami Rawal, Sarita

Gupta

Effect of low level

exposure of lead and

cadmium on hepatic

estradiol metabolism in

female rats.

Indian Journal of

Experimental

Biology

I.F. 1.195

2002 40: 807 –

811

41 Jyoti Maroo, Vihas T.

Vasu,

RavikumarAalinkeel,

Sarita Gupta.

Glucose lowering effect of

aqueous extract of

Enicostemma littorale

Blume in diabetes: a

possible mechanism of

action.

Journal of

Ethnopharmacology

I.F. 3.322

2002 81: 317 –

320

42 Anil Pillai, Laxmipriya

PN, Sarita Gupta

Effects of combined

exposure to lead and

cadmium on pituitary

membrane of female rats

Archives of

Toxicology

I.F. 5.215

2002 76: 671 –

675

43 Sarita Gupta,

Laxmipriya, Vishal

Gohil

Simultaneous exposure of

lead and cadmium on

granulosa cells,

progesterone and

leutinizing hormone in

proestrous rats.

Advances in

Pharmacology and

Toxicology

2002 3: 23 – 30

Prof. Sarita Gupta Bio-Sketch

15

44 Deepali Agrawal,

Mayurbhai H. Sahani,

Sarita Gupta,

Rasheedunnisa Begum.

Vitiligo etiopathogenesis

and therapy – A review.

Journal of The M.S.

University of Baroda

2001 48: 97 –

106

45 Sarita Gupta, Ajit

Pandya, Sharad Gupta

Assessment of lead

exposure in population of

urban, suburban and rural

Baroda.

Journal of The M.S.

University of Baroda

2001 48: 63 – 66

46 Ravi Vijayvargia,

Monika Kumar, Sarita

Gupta

Hypoglycemic effect of

aqueous extract of

Enicostemma littorale

Blume (chhota chirayata)

on alloxan induced

diabetes mellitus in rats.

Indian Journal of

Experimental

Biology

I.F. 1.195

2000 38: 781 –

784

47 Sarita Gupta, Snehalata

Bhosale, Kirtan Pandya

Simultaneous low level

exposure of lead and

cadmium on ALAD and

acetylcholine esterase in

rats.

Indian Journal of

Experimental

Biology

I.F. 1.195

1994 32: 819 –

821

48 Sarita Shah,

Nirmalendu Nath

Effect of castration on the

metabolism of L-ascorbic

acid in rat prostate.

Journal of Nutrition

and Vitaminology

1985 31: 107 –

113.

49 Sarita Shah,

Nirmalendu Nath

Metabolism of L-Ascorbic

acid in prostate of normal

and scorbutic guinea pigs.

Metabolism

I.F. 2.815

1985 34: 912 –

913.

50 Sarita Shah,

Nirmalendu Nath.

Biological synthesis of L-

Ascorbic acid synthesis in

goat prostate.

Biochemistry and

Biophysics Indian

Journal of

I.F. 1.026

1985. 22:43–48

51 Sarita Shah,

Nirmalendu Nath.

Catabolism of L- Ascorbic

acid in rat and goat

prostate.

Indian Journal of

Experimental

Biology

I.F. 1.195

1984 1: 276 –

277.

Patent: Sarita Gupta and R.R. Bhonde. Islet neogenic potential of Methanolic Extract of

Enicostemma littorale herb. Patent filed to Department of Biotechnology Government of India.

Patent Number- #2425/DEL/2009.