ibm marketscan research databases bibliography

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IBM MarketScan Research Databases Bibliography This bibliography features a selection of peer-reviewed research citing the IBM MarketScan Research Databases in diabetes, oncology, cardiovascular, respiratory, immunology, and neurology published from January 1, 2019 through June 30, 2020. For more information about publications in other disease areas, please contact your IBM representative.

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IBM MarketScan Research Databases Bibliography

This bibliography features a selection of peer-reviewed research citing the IBM MarketScan Research Databases in diabetes, oncology, cardiovascular, respiratory, immunology, and neurology published from January 1, 2019 through June 30, 2020. For more information about publications in other disease areas, please contact your IBM representative.

IBM MarketScan Research Databases Bibliography by therapeutic area

Since 1988, healthcare researchers have used the IBM® MarketScan® Research Databases to understand disease progression, treatment patterns, health outcomes, and their associated costs to patients, employers, health plans, and the government. Fully HIPAA compliant, the MarketScan Databases are among the largest proprietary databases used for healthcare research in the United States. They are the basis of over 2,650 peer-reviewed articles published in leading journals since the first article appeared in The New England Journal of Medicine in 1990 (B.J. Hillman et al.). MarketScan-based research has made a substantial contribution to the body of literature used to formulate policy decisions and improve healthcare for Americans. Below we’ve provided the most recent articles based on MarketScan data in 6 key therapeutic areas (from January 1, 2019, through June 30, 2020)

Diabetes

1: Boye KS, Mody R, Lage MJ, Malik RE. The Relationship between Timing of Initiation on a Glucagon-like Peptide-1 Receptor Agonist and Glycosylated Hemoglobin Values Among Patients with Type 2 Diabetes. Clin Ther. 2020 Jul 30:S0149-2918(20)30329-5. doi: 10.1016/j.clinthera.2020.06.019. Epub ahead of print. PMID: 32741645.

2: Lee H, Chung HJ, Pawar A, Patorno E, Kim DH. Evaluation of Risk of Bullous Pemphigoid With Initiation of Dipeptidyl Peptidase-4 Inhibitor vs Second-generation Sulfonylurea. JAMA Dermatol. 2020 Jul 22:e202158. doi:10.1001/jamadermatol.2020.2158. Epub ahead of print. PMID: 32697283; PMCID: PMC7376463.

3: Lage MJ, Boye KS. The relationship between HbA1c reduction and healthcare costs among patients with type 2 diabetes: evidence from a U.S. claims database. Curr Med Res Opin. 2020 Jul 17:1-7. doi: 10.1080/03007995.2020.1787971. Epub ahead of print. PMID: 32643451.

4: Bello NA, Huang Y, Syeda SK, Wright JD, D'Alton ME, Friedman AM. Receipt of Proton-Pump Inhibitors during Pregnancy and Risk for Preeclampsia. Am J Perinatol. 2020 Jul 3. doi: 10.1055/s-0040-1713864. Epub ahead of print. PMID: 32620021.

5: Bullock A, Rowan CG, Oestreicher N, Yeganegi H, Chiorean EG. Real-World Assessment of Health Care Costs for Patients with Metastatic Pancreatic Cancer Following Initiation of First-Line Chemotherapy. J Manag Care Spec Pharm. 2020 Jul;26(7):872-878. doi: 10.18553/jmcp.2020.26.7.872. PMID: 32584677.

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Contents

Introduction 1

Diabetes 1

Oncology 5

Cardiovascular 10

Respiratory 13

Immunology 15

Neurology 16

IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

6: Reddy SR, Chang E, Tarbox MH, Broder MS, Tieu RS, Guthrie S, Vera-Llonch M, Pollock MR. The Clinical and Economic Burden of Newly Diagnosed Hereditary Transthyretin (ATTRv) Amyloidosis: A Retrospective Analysis of Claims Data. Neurol Ther. 2020 May 25. doi: 10.1007/s40120-020-00194-4. Epub ahead of print. PMID: 32451849.

7: Elharram M, Moura CS, Abrahamowicz M, Bernatsky S, Behlouli H, Raparelli V, Pilote L. Novel glucose lowering agents are associated with a lower risk of cardiovascular and adverse events in type 2 diabetes: A population-based analysis. Int J Cardiol. 2020 Jul 1;310:147-154. doi:10.1016/j.ijcard.2020.03.025. Epub 2020 Apr 15. PMID: 32303419.

8: Ellis RP, Hsu HE, Song C, Kuo TC, Martins B, Siracuse JJ, Liu Y, Ash AS. Diagnostic Category Prevalence in 3 Classification Systems Across the Transition to the International Classification of Diseases, Tenth Revision, Clinical Modification. JAMA Netw Open. 2020 Apr 1;3(4):e202280. doi: 10.1001/jamanetworkopen. 2020.2280. PMID: 32267514; PMCID: PMC7142382.

9: Desai RJ, Dejene S, Jin Y, Liu J, Kim SC. Comparative Risk of Diabetes Mellitus in Patients With Rheumatoid Arthritis Treated With Biologic or Targeted Synthetic Disease-Modifying Drugs: A Cohort Study. ACR Open Rheumatol. 2020 Apr;2(4):222-231. doi: 10.1002/acr2.11124. Epub 2020 Apr 8. PMID: 32267094; PMCID: PMC7164631.

10: Suh K, Basu A, Carlson JJ, Branch KR. Exploring Medication Adherence with P2Y<sub>12</sub> Inhibitors Using Conditional and Unconditional Quantile Regression Approaches. Am J Cardiovasc Drugs. 2020 Mar 30. doi:10.1007/s40256-020-00405-1. Epub ahead of print. PMID: 32232734.

11: Sun AJ, Li S, Zhang CA, Jensen TK, Lindahl-Jacobsen R, Eisenberg ML. Parental comorbidity and medication use in the USA: a panel study of 785 000 live births. Hum Reprod. 2020 Mar 27;35(3):669-675. doi: 10.1093/humrep/deaa022.PMID: 32187368.

12: Rundle AG, Torsiello NE, Davis BM, Griffin B, Neugut AI, Levy DL. Analyses of Employer Medical Claims Data to Assess Receipt of High-Priority Preventive Health Services. Am J Prev Med. 2020 May;58(5):715-723. doi: 10.1016/j.amepre.2019.12.016. Epub 2020 Mar 12. PMID: 32173164.

13: Déruaz-Luyet A, Raabe C, Garry EM, Brodovicz KG, Lavery LA. Incidence of lower extremity amputations among patients with type 1 and type 2 diabetes in the United States from 2010 to 2014. Diabetes Obes Metab. 2020 Jul;22(7):1132-1140. doi: 10.1111/dom.14012. Epub 2020 Mar 11. PMID: 32090430; PMCID: PMC7318669.

14: Kasman AM, Zhang CA, Li S, Stevenson DK, Shaw GM, Eisenberg ML. Association of preconception paternal health on perinatal outcomes: analysis of U.S. claims data. Fertil Steril. 2020 May;113(5):947-954. doi:10.1016/j.fertnstert.2019.12.026. Epub 2020 Mar 6. PMID: 32147174.

15: Mulhall JP, Chopra I, Patel D, Hassan TA, Tang WY. Phosphodiesterase Type-5 Inhibitor Prescription Patterns in the United States Among Men With Erectile Dysfunction: An Update. J Sex Med. 2020 May;17(5):941-948. doi:10.1016/j.jsxm.2020. 01.027. Epub 2020 Mar 3. PMID: 32144034.

16: Wang T, Patel SM, Hickman A, Liu X, Jones PL, Gantz I, Koro CE. SGLT2 Inhibitors and the Risk of Hospitalization for Fournier's Gangrene: A Nested Case-Control Study. Diabetes Ther. 2020 Mar;11(3):711-723. doi: 10.1007/s13300-020-00771-8. Epub 2020 Feb 12. PMID: 32052281; PMCID: PMC7048884.

17: Kiss S, Malangone-Monaco E, Wilson K, Varker H, Stetsovsky D, Smith D, Garmo V. Real-World Injection Frequency and Cost of Ranibizumab and Aflibercept for the Treatment of Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema. J Manag Care Spec Pharm. 2020 Mar;26(3):253-266. doi:10.18553/ jmcp.2020.19245. Epub 2020 Feb 5. PMID: 32020843.

18: Khan T, Yang J, Wozniak G. Trends in Medical Expenditures Prior to Diabetes Diagnosis: The Early Burden of Diabetes. Popul Health Manag. 2020 Feb 3. doi:10.1089/pop.2019.0143. Epub ahead of print. PMID: 32013762.

19: Kiyani M, Yang Z, Charalambous LT, Adil SM, Lee HJ, Yang S, Pagadala P, Parente B, Spratt SE, Lad SP. Painful diabetic peripheral neuropathy: Health care costs and complications from 2010 to 2015. Neurol Clin Pract. 2020 Feb;10(1):47-57. doi: 10.1212/CPJ.0000000000000671. PMID: 32190420; PMCID: PMC7057074.

20: Miao B, Sood N, Bunz TJ, Coleman CI. Rivaroxaban versus apixaban in non- valvular atrial fibrillation patients with end-stage renal disease or receiving dialysis. Eur J Haematol. 2020 Apr;104 (4):328-335. doi: 10.1111/ejh.13383. Epub 2020 Jan 29. PMID: 31925840.

21: Brown TM, Bittner V, Colantonio LD, Deng L, Farkouh ME, Limdi N, Monda KL, Rosenson RS, Serban MC, Somaratne RM, Zhao H, Woodward M, Muntner P. Residual risk for coronary heart disease events and mortality despite intensive medical management after myocardial infarction. J Clin Lipidol. 2020 Mar- Apr;14(2):260-270. doi: 10.1016/j.jacl.2020.01.004. Epub 2020 Jan 23. PMID: 32115398.

22: Lee H, Okunev I, Tranby E, Monopoli M. Different levels of associations between medical co-morbidities and preterm birth outcomes among racial/ethnic women enrolled in Medicaid 2014-2015: retrospective analysis. BMC Pregnancy Childbirth. 2020 Jan 13;20(1):33. doi: 10.1186/s12884-020-2722-8. PMID: 31931778; PMCID: PMC6958731.

23: Raparelli V, Elharram M, Moura CS, Abrahamowicz M, Bernatsky S, Behlouli H, Pilote L. Sex Differences in Cardiovascular Effectiveness of Newer Glucose- Lowering Drugs Added to Metformin in Type 2 Diabetes Mellitus. J Am Heart Assoc. 2020 Jan 7;9(1):e012940. doi: 10.1161/JAHA.119.012940. Epub 2020 Jan 4. PMID: 31902326; PMCID: PMC6988160.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

24: Yang JY, Wang T, Pate V, Buse JB, Stürmer T. Real-world evidence on sodium- glucose cotransporter-2 inhibitor use and risk of Fournier's gangrene. BMJ Open Diabetes Res Care. 2020 Jan;8(1): e000985. doi: 10.1136/bmjdrc-2019-000985. PMID: 31958306; PMCID: PMC7039596. 25: Gor D, Lee TA, Schumock GT, Walton SM, Gerber BS, Nutescu EA, Touchette DR. Adherence and Persistence with DPP-4 Inhibitors Versus Pioglitazone in Type 2 Diabetes Patients with Chronic Kidney Disease: A Retrospective Claims Database Analysis. J Manag Care Spec Pharm. 2020 Jan;26(1):67-75. doi:10.18553/jmcp.2020.26 .1.67. PMID: 31880221. 26: Miller AC, Comellas AP, Hornick DB, Stoltz DA, Cavanaugh JE, Gerke AK, Welsh MJ, Zabner J, Polgreen PM. Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1621-1627. doi: 10.1073/pnas.1914912117. Epub 2019 Dec 27. PMID: 31882447; PMCID: PMC6983448. 27: Chen YW, Voelker J, Tunceli O, Pericone CD, Bookhart B, Durkin M. Real-world comparison of hospitalization costs for heart failure in type 2 diabetes mellitus patients with established cardiovascular disease treated with canagliflozin versus other antihyperglycemic agents. J Med Econ. 2020 Apr;23(4):401-406. doi:10.1080/13696998. 2019.1693384. Epub 2019 Dec 4. PMID: 31801393. 28: Lee H, Jin Y, Liu J, Cohen EM, Chen SK, Kim SC. Risk of Diabetes Mellitus in Patients with Juvenile Idiopathic Arthritis. J Rheumatol. 2020 Sep 1;47(9):1405-1408. doi:10.3899/ jrheum.190644. Epub 2019 Dec 1. PMID: 31787600. 29: Elsaid MI, John T, Li Y, Koduru S, Ali SZ, Catalano C, Narayanan N, Rustgi VK. Health Care Utilization and Economic Burdens of Hemochromatosis in the United States: A Population-Based Claims Study. J Manag Care Spec Pharm. 2019 Dec;25(12):1377-1386. doi: 10.18553/jmcp.2019.25.12.1377. PMID: 31778618. 30: Olds C, Spataro E, Li K, Kandathil C, Most SP. Postoperative Antibiotic Use Among Patients Undergoing Functional Facial Plastic and Reconstructive Surgery. JAMA Facial Plast Surg. 2019 Dec 1;21(6):491-497. doi:10.1001/jamafacial.2019.1027. PMID: 31647506; PMCID: PMC6813590. 31: Lutsey PL, Norby FL, Ensrud KE, MacLehose RF, Diem SJ, Chen LY, Alonso A. Association of Anticoagulant Therapy With Risk of Fracture Among Patients With Atrial Fibrillation. JAMA Intern Med. 2019 Nov 25;180(2):245–53. doi:10.1001/jamainternmed. 2019. 5679. Epub ahead of print. PMID: 31764956; PMCID: PMC6902159. 32: Badawy SM, Payne AB. Association between clinical outcomes and metformin use in adults with sickle cell disease and diabetes mellitus. Blood Adv. 2019 Nov 12;3(21):3297-3306. doi:10.1182/ bloodadvances.2019000838. PMID: 31698459; PMCID: PMC6855104.

33: Nestsiarovich A, Kerner B, Mazurie AJ, Cannon DC, Hurwitz NG, Zhu Y, Nelson SJ, Oprea TI, Crisanti AS, Tohen M, Perkins DJ, Lambert CG. Diabetes mellitu risk for 102 drugs and drug combinations used in patients with bipolar disorder. Psychoneuroendocrinology. 2020 Feb;112:104511. doi: 10.1016/j.psyneuen.2019.104511. Epub 2019 Nov 9. PMID: 31744781. 34: Ludwig CA, Vail D, Callaway NF, Pasricha MV, Moshfeghi DM. Pentosan Polysulfate Sodium Exposure and Drug-Induced Maculopathy in Commercially Insured Patients in the United States. Ophthalmology. 2020 Apr;127(4):535-543. doi:10.1016/ j.ophtha.2019.10.036. Epub 2019 Nov 5. PMID: 31899034. 35: Cesta CE, Cohen JM, Pazzagli L, Bateman BT, Bröms G, Einarsdóttir K, Furu K, Havard A, Heino A, Hernandez-Diaz S, Huybrechts KF, Karlstad Ø, Kieler H, Li J, Leinonen MK, Gulseth HL, Tran D, Yu Y, Zoega H, Odsbu I. Antidiabetic medication use during pregnancy: an international utilization study. BMJ Open Diabetes Res Care. 2019 Nov 2;7(1):e000759. doi: 10.1136/bmjdrc-2019-000759. PMID: 31798900; PMCID: PMC6861111. 36: Fendrick AM, Buxbaum JD, Tang Y, Vlahiotis A, McMorrow D, Rajpathak S, Chernew ME. Association Between Switching to a High-Deductible Health Plan and Discontinuation of Type 2 Diabetes Treatment. JAMA Netw Open. 2019 Nov 1;2(11): e1914372. doi: 10.1001/jamanetworkopen.2019.14372. PMID: 31675081; PMCID: PMC6826641. 37: Adimadhyam S, Lee TA, Calip GS, Smith Marsh DE, Layden BT, Schumock GT. Sodium-glucose co-transporter 2 inhibitors and the risk of fractures: A propensity score-matched cohort study. Pharmacoepidemiol Drug Saf. 2019 Dec;28(12):1629-1639. doi: 10.1002/pds.4900. Epub 2019 Oct 24. PMID: 31646732. 38: Keshishian A, Xie L, Dembek C, Yuce H. Reduction in Hospital Readmission Rates Among Medicare Beneficiaries With Chronic Obstructive Pulmonary Disease: A Real-world Outcomes Study of Nebulized Bronchodilators. Clin Ther. 2019 Nov;41(11):2283-2296. doi: 10.1016/j.clinthera.2019.09.001. Epub 2019 Oct 17. PMID: 31630815. 39: Lopez DS, Huang D, Tsilidis KK, Khera M, Williams SB, Urban RJ, Panagiotou OA, Kuo YF, Baillargeon J, Farias A, Krause T. Association of the extent of therapy with prostate cancer in those receiving testosterone therapy in a US commercial insurance claims database. Clin Endocrinol (Oxf). 2019 Dec;91(6):885-891. doi: 10.1111/cen.14093. Epub 2019 Oct 7. PMID: 31498469; PMCID: PMC7294776. 40: Saydah SH, Shrestha SS, Zhang P, Zhou X, Imperatore G. Medical Costs Among Youth Younger Than 20 Years of Age With and Without Diabetic Ketoacidosis at the Time of Diabetes Diagnosis. Diabetes Care. 2019 Dec;42(12):2256-2261. doi: 10.2337/dc19-1041. Epub 2019 Oct 1. PMID: 31575641. 41: Dashputre AA, S Gatwood K, Schmidt J, Gatwood J. Impact of oral oncolytic initiation on medication adherence for pre-existing comorbid chronic conditions. J Oncol Pharm Pract. 2020 Jun;26 (4):835-845. doi: 10.1177/1078155219875206. Epub 2019 Oct 1. PMID: 31575355.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

42: Margolis JM, Princic N, Smith DM, Abraham L, Cappelleri JC, Shah SN, Park PW. Economic Impact of Adherence to Pain Treatment Guidelines in Chronic Pain Patients. Pain Med. 2019 Oct 1;20(10): 1907-1918. doi: 10.1093/pm/pnz085. PMID: 31034040. 43: Edelman SV, Ermakova A, Xiong Y, Sieradzan R, Taylor SD. Persistence with Basal-Bolus Insulin Therapy in Patients with Type 2 Diabetes Mellitus and Effect on Clinical and Economic Outcomes: A Retrospective Claims Database Study. J Manag Care Spec Pharm. 2019 Dec;25(12):1420-1431. doi:0.18553/jmcp. 2019.19097. Epub 2019 Sep 24. PMID: 31550190. 44: Wang T, Yang JY, Buse JB, Pate V, Tang H, Barnes EL, Sandler RS, Stürmer T. Dipeptidyl Peptidase 4 Inhibitors and Risk of Inflammatory Bowel Disease: Real-world Evidence in U.S. Adults. Diabetes Care. 2019 Nov;42(11):2065-2074. doi:10.2337/dc19-0162. Epub 2019 Aug 30. PMID: 31471377; PMCID: PMC6804610. 45: Wetmore JB, Li S, Ton TGN, Peng Y, Hansen MK, Neslusan C, Riley R, Liu J, Gilbertson DT. Association of diabetes-related kidney disease with cardiovascular and non-cardiovascular outcomes: a retrospective cohort study. BMC Endocr Disord. 2019 Aug 27;19(1):89. doi:10.1186/s12902-019-0417-9. PMID: 31455289; PMCID: PMC6712860. 46: Hernandez AV, Bradley G, Khan M, Fratoni A, Gasparini A, Roman YM, Bunz TJ, Eriksson D, Meinecke AK, Coleman CI. Rivaroxaban Versus Warfarin and Renal Outcomes in Non-valvular Atrial Fibrillation Patients with Diabetes. Eur Heart J Qual Care Clin Outcomes. 2019 Aug 20:qcz047. doi: 10.1093/ehjqcco/qcz047. Epub ahead of print. PMID: 31432074. 47: Zhuang S, Na M, Winkelman JW, Ba D, Liu CF, Liu G, Gao X. Association of Restless Legs Syndrome With Risk of Suicide and Self-harm. JAMA Netw Open. 2019 Aug 2;2(8):e199966. doi:10.1001/ jamanetworkopen.2019.9966. PMID: 31441941; PMCID: PMC6714009. 48: Early NK, Fairman KA, Hagarty JM, Sclar DA. Joint effects of advancing age and number of potentially inappropriate medication classes on risk of falls in Medicare enrollees. BMC Geriatr. 2019 Jul 19;19(1):194. doi:10.1186/s12877-019-1202-3. PMID: 31324232; PMCID: PMC6642496. 49: McDowell A, Progovac AM, Cook BL, Rose S. Estimating the Health Status of Privately Insured Gender Minority Children and Adults. LGBT Health. 2019 Aug/Sep;6(6):289-296. doi:10.1089/ lgbt.2018.0238. Epub 2019 Jul 17. PMID: 31314674. 50: Kohn JR, Rajan SS, Kushner JA, Fox KA. Outcomes, care utilization, and expenditures in adolescent pregnancy complicated by diabetes. Pediatr Diabetes. 2019 Sep;20(6):769-777. doi: 10.1111/pedi.12871. Epub 2019 Jul 1. PMID: 31125158.

51: Baker WL, Beyer-Westendorf J, Bunz TJ, Eriksson D, Meinecke AK, Sood NA, Coleman CI. Effectiveness and safety of rivaroxaban and warfarin for prevention of major adverse cardiovascular or limb events in patients with non-valvular atrial fibrillation and type 2 diabetes. Diabetes Obes Metab. 2019 Sep;21(9):2107-2114. doi: 10.1111/dom.13787. Epub 2019 Jun 11. PMID: 31099460. 52: Vail D, Callaway NF, Ludwig CA, Saroj N, Moshfeghi DM. Lipid-Lowering Medications Are Associated with Lower Risk of Retinopathy and Ophthalmic Interventions among United States Patients with Diabetes. Am J Ophthalmol. 2019 Nov;207:378-384. doi: 10.1016/j.ajo.2019.05.029. Epub 2019 Jun 10. PMID: 31194953. 53: Pal S, Gong J, Mhatre SK, Lin SW, Surinach A, Ogale S, Vohra R, Wallen H, George D. Real-world treatment patterns and adverse events in metastatic renal cell carcinoma from a large US claims database. BMC Cancer. 2019 Jun 7;19(1):548. doi: 10.1186/ s12885-019-5716-z. PMID: 31174493; PMCID: PMC6555983. 54: Weeda ER, Cassarly C, Brinton DL, Shirley DW, Simpson KN. Loop diuretic use among patients with heart failure and type 2 diabetes treated with sodium glucose cotransporter-2 inhibitors. J Diabetes Complications. 2019 Aug;33(8):567-571. doi:10.1016/ j.jdiacomp.2019.05.001. Epub 2019 May 10. PMID: 31176543; PMCID: PMC6613996. 55: Malhamé I, Dayan N, Moura CS, Samuel M, Vinet E, Pilote L. Peripartum cardiomyopathy with co-incident preeclampsia: A cohort study of clinical risk factors and outcomes among commercially insured women. Pregnancy Hypertens. 2019 Jul;17:82-88. doi: 10.1016/j.preghy.2019.05.014. Epub 2019 May 9. PMID: 31487662. 56: Edmiston CE Jr, Chitnis AS, Lerner J, Folly E, Holy CE, Leaper D. Impact of patient comorbidities on surgical site infection within 90 days of primary and revision joint (hip and knee) replacement. Am J Infect Control. 2019 Oct;47(10):1225-1232. doi: 10.1016/ j.ajic.2019.03.030. Epub 2019 May 7. PMID: 31072674. 57: Johnston SS, Morton JM, Kalsekar I, Ammann EM, Hsiao CW, Reps J. Using Machine Learning Applied to Real-World Healthcare Data for Predictive Analytics: An Applied Example in Bariatric Surgery. Value Health. 2019 May;22(5):580-586. doi: 10.1016/ j.jval.2019.01.011. PMID: 31104738. 58: Chen Y, Wang T, Liu X, Shankar RR. Prevalence of type 1 and type 2 diabetes among US pediatric population in the MarketScan Multi-State Database, 2002 to 2016. Pediatr Diabetes. 2019 Aug;20(5):523-529. doi: 10.1111/pedi.12842. Epub 2019 Apr 25. PMID: 30861241. 59: Sparks JA, Lesperance T, Accortt NA, Solomon DH. Subsequent Cardiovascular Events Among Patients With Rheumatoid Arthritis, Psoriatic Arthritis, or Psoriasis: Patterns of Disease-Modifying Antirheumatic Drug Treatment. Arthritis Care Res (Hoboken). 2019 Apr;71(4):512-520. doi: 10.1002/acr.23609. PMID: 29799667; PMCID: PMC6252288.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

60: Yang JY, Wang T, Pate V, Gower EW, Crowley MJ, Buse JB, Stürmer T. Sodium- glucose co-transporter-2 inhibitor use and risk of lower-extremity amputation: Evolving questions, evolving answers. Diabetes Obes Metab. 2019 May;21(5):1223-1236. doi: 10.1111/ dom.13647. Epub 2019 Mar 4. PMID: 30697897; PMCID: PMC6459697. 61: Kong AM, Pozen A, Anastos K, Kelvin EA, Nash D. Non-HIV Comorbid Conditions and Polypharmacy Among People Living with HIV Age 65 or Older Compared with HIV-Negative Individuals Age 65 or Older in the United States: A Retrospective Claims-Based Analysis. AIDS Patient Care STDS. 2019 Mar;33(3):93-103. doi:10.1089/ apc.2018.0190. PMID: 30844304; PMCID: PMC6939583. 62: Xu Y, Pilla SJ, Alexander GC, Murimi IB. Use of non-insulin diabetes medicines after insulin initiation: A retrospective cohort study. PLoS One. 2019 Feb 13;14(2):e0211820. doi:10.1371/ journal.pone.0211820. PMID: 30759121; PMCID: PMC6373953. 63: Alvarez PA, Truong CN, Briasoulis A, Ganduglia-Cazaban C. Prescription of Potentially Harmful Drugs in Young Adults With Heart Failure and Reduced Ejection Fraction. Am J Cardiol. 2019 May 1;123(9):1458-1463. doi:10.1016/j.amjcard.2019.01.052. Epub 2019 Feb 10. PMID: 30791999. 64: Colantonio LD, Rosenson RS, Deng L, Monda KL, Dai Y, Farkouh ME, Safford MM, Philip K, Mues KE, Muntner P. Adherence to Statin Therapy Among US Adults Between 2007 and 2014. J Am Heart Assoc. 2019 Jan 8;8(1):e010376. doi:10.1161/JAHA.118. 010376. PMID: 30616455; PMCID: PMC6405715. 65: Zhou J, Han J, Nutescu EA, Patel PR, Sweiss K, Calip GS. Discontinuation and Nonadherence to Medications for Chronic Conditions after Hematopoietic Cell Transplantation: A 6-Year Propensity Score-Matched Cohort Study. Pharmacotherapy. 2019 Jan;39(1):55-66. doi: 10.1002/phar.2197. Epub 2019 Jan 4. PMID: 30485471. 66: Shrestha SS, Zhang P, Hora IA, Gregg EW. Trajectory of Excess MedicalExpenditures 10 Years Before and After Diabetes Diagnosis Among U.S. Adults Aged 25-64 Years, 2001-2013. Diabetes Care. 2019 Jan;42(1):62-68. doi:10.2337/dc17-2683. Epub 2018 Nov 19. PMID: 30455325; PMCID: PMC6393199. 67: Adimadhyam S, Schumock GT, Calip GS, Smith Marsh DE, Layden BT, Lee TA. Increased risk of mycotic infections associated with sodium-glucose co-transporter 2 inhibitors: a prescription sequence symmetry analysis. Br J Clin Pharmacol. 2019 Jan;85(1): 160-168. doi: 10.1111/bcp.13782. Epub 2018 Nov 8. PMID: 30294925; PMCID: PMC6303242. 68: Basak R, Bentley JP, McCaffrey DJ 3rd, West-Strum D, Przybyla SM, Banahan BF 3rd. Comparing algorithms for composite measures of intra-disease multiple medication adherence: The case of diabetes. Res Social Adm Pharm. 2019 Sep;15(9):1160-1167. doi:10.1016/ j.sapharm.2018.09.024. Epub 2018 Oct 2. PMID: 30301682.

69: Falowski SM, Provenzano DA, Xia Y, Doth AH. Spinal Cord Stimulation Infection Rate and Risk Factors: Results From a United States Payer Database. Neuromodulation. 2019 Feb;22(2):179-189. doi: 10.1111/ner.12843. Epub 2018 Aug 17. PMID: 30117635; PMCID: PMC6585777. 70: Dawwas GK, Smith SM, Park H. Cardiovascular outcomes of sodium glucose cotransporter-2 inhibitors in patients with type 2 diabetes. Diabetes Obes Metab. 2019 Jan;21(1):28-36. doi: 10.1111/dom.13477. Epub 2018 Aug 16. PMID: 30039524. 71: Kaine J, Song X, Kim G, Hur P, Palmer JB. Higher Incidence Rates of Comorbidities in Patients with Psoriatic Arthritis Compared with the General Population Using U.S. Administrative Claims Data. J Manag Care Spec Pharm. 2019 Jan;25(1):122-132. doi: 10.18553/jmcp.2018.17421. Epub 2018 Apr 25. PMID: 29694270

Oncology 1: Lutsey PL, MacLehose RF, Claxton JS, Walker RF, Adam TJ, Alonso A, Zakai NA. Impact of oral anticoagulation choice on healthcare utilization for the primary treatment of venous thromboembolism. Vasc Med. 2020 Jul 27:1358863X20940388. doi: 10.1177/1358863X20940388. Epub ahead of print. PMID: 32716254. 2: McEvoy AM, Poplack S, Nickel K, Olsen MA, Ademuyiwa F, Zoberi I, Odom E, Yu J, Chang SH, Gillanders WE. Cost-effectiveness analyses demonstrate that observation is superior to sentinel lymph node biopsy for postmenopausal women with HR + breast cancer and negative axillary ultrasound. Breast Cancer Res Treat. 2020 Sep;183(2):251-262. doi: 10.1007/s10549-020-05768-2. Epub 2020 Jul 10. PMID: 32651755. 3: Bello NA, Huang Y, Syeda SK, Wright JD, D'Alton ME, Friedman AM. Receipt of Proton-Pump Inhibitors during Pregnancy and Risk for Preeclampsia. Am J Perinatol. 2020 Jul 3. doi: 10.1055/s-0040-1713864. Epub ahead of print. PMID: 32620021. 4: Bullock A, Rowan CG, Oestreicher N, Yeganegi H, Chiorean EG. Real-World Assessment of Health Care Costs for Patients with Metastatic Pancreatic Cancer Following Initiation of First-Line Chemotherapy. J Manag Care Spec Pharm. 2020 Jul;26(7):872-878. doi: 10.18553/jmcp.2020.26.7.872. PMID: 32584677. 5: Sharma M, Duan Z, Zhao H, Giordano SH, Chavez-MacGregor M. Real-World Patterns of Everolimus Use in Patients with Metastatic Breast Cancer. Oncologist. 2020 May 31. doi:10.1634/ theoncologist.2019-0602. Epub ahead of print. PMID: 32476216. 6: Shen C, Thornton JD, Gu D, Dodge D, Zhou S, He W, Zhao H, Giordano SH. Prolonged Opioid Use After Surgery for Early-Stage Breast Cancer. Oncologist. 2020 May 11. doi:10.1634/ theoncologist.2019-0868. Epub ahead of print. PMID: 32390251.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

7: Princic N, McMorrow D, Chan P, Hess L. Evaluation of the accuracy of algorithms to identify soft tissue sarcoma (STS) in administrative claims. Clin Sarcoma Res. 2020 May 5;10:8. doi: 10.1186/s13569-020-00130-y. PMID: 32391140; PMCID: PMC7199315. 8: Wu CF, Lairson DR, Dahlstrom KR, Fokom Domgue J, Fu S, Sturgis EM, Chan W. Lifetime health care costs of oropharyngeal cancer for commercially insured patients in the United States. Head Neck. 2020 Sep;42(9):2321-2329. doi:10.1002/hed.26201. Epub 2020 May 2. PMID: 32359131. 9: Pucheril D, Fletcher SA, Chen X, Friedlander DF, Cole AP, Krimphove MJ, Fields AC, Melnitchouk N, Kibel AS, Dasgupta P, Trinh QD. Workplace absenteeism amongst patients undergoing open vs. robotic radical prostatectomy, hysterectomy, and partial colectomy. Surg Endosc. 2020 Apr 14. doi:10.1007/s00464-020-07547-y. Epub ahead of print. PMID: 32291540. 10: Mascarenhas J, Mehra M, He J, Potluri R, Loefgren C. Patient characteristicsand outcomes after ruxolitinib discontinuation in patients with myelofibrosis. J Med Econ. 2020 Jul;23(7):721-727. doi: 10.1080/13696998.2020.1741381. Epub 2020 Mar 31. PMID: 32159402. 11: Sussell JA, Sheinson D, Wu N, Shah-Manek B, Seetasith A. HER2-Positive Metastatic Breast Cancer: A Retrospective Cohort Study of Healthcare Costs in the Targeted-Therapy Age. Adv Ther. 2020 Apr;37(4):1632-1645. doi:10.1007/s12325-020-01283-4. Epub 2020 Mar 14. PMID: 32172510. 12: Bonafede MM, Korytowsky B, Singh P, Cai Q, Cappell K, Jariwala-Parikh K, Sill B, Parikh ND. Treatment Patterns and Economic Burden by Lines of Therapy Among Patients with Advanced Hepatocellular Carcinoma Treated with Systemic Cancer Therapy. J Gastrointest Cancer. 2020 Mar;51(1):217-226. doi:10.1007/s12029-019-00230-z. PMID: 31011982; PMCID: PMC7000498. 13: Calip GS, Patel PR, Sweiss K, Wu Z, Zhou J, Asfaw AA, Adimadhyam S, Lee TA, Chiu BC. Targets of biologic disease-modifying antirheumatic drugs and risk of multiple myeloma. Int J Cancer. 2020 Sep 1;147(5):1300-1305. doi:10.1002/ijc.32891. Epub 2020 Feb 8. PMID: 31997371; PMCID: PMC7426969. 14: Pendharkar AV, Rezaii PG, Ho AL, Sussman ES, Li G, Desai AM. Functional Mapping for Glioma Surgery: A Propensity-Matched Analysis of Outcomes and Cost. World Neurosurg. 2020 May;137: e328-e335. doi: 10.1016/j.wneu.2020.01.197. Epub 2020 Feb 3. PMID: 32028000. 15: Kenzik KM, Bhatia R, Bhatia S. Expenditures for First- and Second-Generation Tyrosine Kinase Inhibitors Before and After Transition of Imatinib to Generic Status. JAMA Oncol. 2020 Jan 30;6(4):542–6. doi: 10.1001/jamaoncol.2019.6390. Epub ahead of print. PMID: 31999305; PMCID: PMC7042837.

16: Gorski JW, Quattrone M, van Nagell JR, Pavlik EJ. Assessing the Costs of Screening for Ovarian Cancer in the United States: An Evolving Analysis. Diagnostics (Basel). 2020 Jan 25;10(2):67. doi: 10.3390/diagnostics10020067. PMID: 31991783; PMCID: PMC7168929. 17: O'Brien SH, Stanek JR, Kaur D, McCracken K, Vesely SK. Laboratory monitoring during pregnancy and post-partum hemorrhage in women with von Willebrand disease. J Thromb Haemost. 2020 Mar;18(3):604-608. doi: 10.1111/jth.14696. Epub 2020 Jan 22. PMID: 31808272. 18: Krimphove MJ, Reese S, Chen X, Marchese M, Cone E, Tully KH, Paciotti M, Kibel AS, Melnitchouk N, Kluth LA, Dasgupta P, Trinh QD. Minimally invasive cancer surgery is associated with a lower risk of venous thromboembolic events. J Surg Oncol. 2020 Mar;121(3):578-583. doi: 10.1002/jso.25832. Epub 2020 Jan 8. PMID: 31916588. 19: Nabi J, Friedlander DF, Chen X, Cole AP, Hu JC, Kibel AS, Dasgupta P, Trinh QD. Assessment of Out-of-Pocket Costs for Robotic Cancer Surgery in US Adults. JAMA Netw Open. 2020 Jan 3;3(1):e1919185. doi:10.1001/jamanetworkopen.2019.19185. PMID: 31940036; PMCID: PMC6991257. 20: Zhou J, Nutescu EA, Han J, Calip GS. Clinical trajectories, healthcare resource use, and costs of long-term hematopoietic stem cell transplantation survivors: a latent class analysis. J Cancer Surviv. 2020 Jun;14(3):294-304. doi: 10.1007/s11764-019-00842-1. Epub 2020 Jan 2. PMID: 31897877; PMCID: PMC7390707. 21: Dasari A, Joish VN, Perez-Olle R, Dharba S, Balaji K, Halperin DM. Direct costs of carcinoid syndrome diarrhea among adults in the United States. World J Gastroenterol. 2019 Dec21;25(47): 6857-6865. doi: 10.3748/wjg.v25.i47.6857. PMID: 31885426; PMCID: PMC6931008. 22: Harrison R, Zhao H, Sun CC, Fu S, Armbruster SD, Westin SN, Rauh-Hain JA, Lu KH, Giordano SH, Meyer LA. Body mass index and attitudes towards health behaviors among women with endometrial cancer before and after treatment. Int J Gynecol Cancer. 2020 Feb;30(2):187-192. doi: 10.1136/ijgc-2019-000999. Epub 2019 Dec 15. PMID: 31843871; PMCID: PMC7307445. 23: Youngerman BE, Joiner EF, Wang X, Yang J, Welch MR, McKhann GM 2nd, Wright JD, Hershman DL, Neugut AI, Bruce JN. Patterns of seizure prophylaxis after oncologic neurosurgery. J Neurooncol. 2020 Jan;146(1):171-180. doi:10.1007/s11060-019-03362-1. Epub 2019 Dec 13. PMID: 31834582. 24: Cai B, Said Q, Li X, Li FY, Arcona S. Healthcare resource use and direct costs in severe aplastic anemia (SAA) patients before and after treatment with eltrombopag. J Med Econ. 2020 Mar;23(3): 243-251. doi:10.1080/13696998.2019.1688820. Epub 2019 Nov 20. PMID: 31686551.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

25: Badawy SM, Payne AB. Association between clinical outcomes and metformin use in adults with sickle cell disease and diabetes mellitus. Blood Adv. 2019 Nov 12;3(21):3297-3306. doi:10.1182/ bloodadvances.2019000838. PMID: 31698459; PMCID: PMC6855104. 26: Simon TA, Boers M, Hochberg M, Baker N, Skovron ML, Ray N, Singhal S, Suissa S, Gomez-Caminero A. Comparative risk of malignancies and infections in patients with rheumatoid arthritis initiating abatacept versus other biologics: a multi-database real-world study. Arthritis Res Ther. 2019 Nov 8;21(1):228. doi:10.1186/ s13075-019-1992-x. PMID: 31703717; PMCID: PMC6839238. 27: Billig JI, Hsu JJ, Zhong L, Wang L, Chung KC, Kung TA. Comparison of Effective Cost and Complications after Abdominoperineal Resection: Primary Closure versus Flap Reconstruction. Plast Reconstr Surg. 2019 Nov;144(5):866e-875e. doi:10.1097/PRS. 0000000000006158. PMID: 31688766. 28: Fendrick AM, Buxbaum JD, Tang Y, Vlahiotis A, McMorrow D, Rajpathak S, Chernew ME. Association Between Switching to a High-Deductible Health Plan and Discontinuation of Type 2 Diabetes Treatment. JAMA Netw Open. 2019 Nov 1;2(11): e1914372. doi: 10.1001/jamanetworkopen.2019.14372. PMID: 31675081; PMCID: PMC6826641. 29: Harrington RL, Qato DM, Antoon JW, Caskey RN, Schumock GT, Lee TA. Impact of multimorbidity subgroups on the health care use of early pediatric cancer survivors. Cancer. 2020 Feb 1;126(3): 649-658. doi: 10.1002/cncr.32201. Epub 2019 Oct 22. PMID: 31639197. 30: Ailawadhi S, Medhekar R, Princic N, Fowler R, Tran O, Bhowmik D, Panjabi S. Healthcare resource utilization and costs in patients with multiple myeloma with and without skeletal-related events. J Oncol Pharm Pract. 2020 Jul;26(5):1070-1079. doi:10.1177/ 1078155219881489. Epub 2019 Oct 20. PMID: 31631810. 31: Wu B, Li SS, Song J, Pericone CD, Behl AS, Dawson NA. Total cost of care for castration-resistant prostate cancer in a commercially insured population and a medicare supplemental insured population. J Med Econ. 2020 Jan;23(1):54-63. doi:10.1080/13696998. 2019. 1678171. Epub 2019 Oct 18. PMID: 31589086. 32: Kanter J, Bhor M, Li X, Li FY, Paulose J. High Healthcare Utilization in Adolescents with Sickle Cell Disease Prior to Transition to Adult Care: A Retrospective Study. J Health Econ Outcomes Res. 2019 Oct 9;6(3):174-184. doi:10.36469/10512. PMID: 32685589; PMCID: PMC7299476. 33: Phuar HL, Begley CE, Chan W, Krause TM. Tyrosine Kinase Inhibitors Initiation, Cost Sharing, and Health Care Utilization in Patients with Newly Diagnosed Chronic Myeloid Leukemia: A Retrospective Claims-Based Study. J Manag Care Spec Pharm. 2019 Oct;25(10):1140-1150. doi:10.18553/jmcp. 2019.25.10.1140. PMID: 31556823.

34: Vande Walle K, Yang DY, Stankowski-Drengler TJ, Livingston-Rosanoff D, Fernandes-Taylor S, Schumacher JR, Wilke LG, Greenberg CC, Neuman HB. Breast Cancer Found Incidentally After Reduction Mammaplasty in Young Insured Women. Ann Surg Oncol. 2019 Dec;26(13):4310-4316. doi: 10.1245/s10434-019-07726-9. Epub 2019 Sep 19. PMID: 31538286. 35: Pastuszak AW, Thirumavalavan N, Kohn TP, Lipshultz LI, Eisenberg ML. Increased Risk of Cancer in Men With Peyronie's Disease: A Cohort Study Using a Large United States Insurance Claims Database. Sex Med. 2019 Dec;7(4):403-408. doi: 10.1016/ j.esxm.2019.08.007. Epub 2019 Sep 14. PMID: 31530474; PMCID: PMC6963113. 36: Cohen JT, Lin PJ, Sheinson DM, Wong WB, Wu N, Yim YM, Ramsey SD. Are National Comprehensive Cancer Network Evidence Block Affordability Ratings Representative of Real-World Costs? An Evaluation of Advanced Non-Small-Cell Lung Cancer. J Oncol Pract. 2019 Nov;15(11):e948-e956. doi:10.1200/JOP. 19.00241. Epub 2019 Sep 12. PMID: 31513478. 37: Cole AL, Jazowski SA, Dusetzina SB. Initiation of generic imatinib may improve medication adherence for patients with chronic myeloid leukemia. Pharmacoepidemiol Drug Saf. 2019 Nov;28(11):1529-1533. doi: 10.1002/pds.4893. Epub 2019 Sep 11. PMID: 31507005. 38: Fisher AV, Hanlon B, Fernandes-Taylor S, Schumacher JR, Lawson EH, Ronnekleiv-Kelly SM, Minter RM, Weber SM, Abbott DE. Natural history and cost analysis of surgical bypass versus endoscopic stenting for the palliative management of malignant gastric outlet obstruction. HPB (Oxford). 2020 Apr;22(4):529-536. doi: 10.1016/j.hpb.2019.08.009. Epub 2019 Sep 10. PMID: 31519358. 39: McDonald L, Behl V, Sundar V, Mehmud F, Malcolm B, Ramagopalan S. Validity of social media for assessing treatment patterns in oncology patients: a case study in melanoma. JAMIA Open. 2019 Sep 3;2(4):416-422. doi:10.1093/jamiaopen/ooz013. PMID: 32025637; PMCID: PMC6994021. 40: Shih V, Banks E, Bonine NG, Harrington A, Stafkey-Mailey D, Yue B, Ye JM, Fuldeore RM, Gillard P. Healthcare resource utilization and costs among women diagnosed with uterine fibroids compared to women without uterine fibroids. Curr Med Res Opin. 2019 Nov;35(11):1925-1935. doi:10.1080/03007995. 2019.1642186. Epub 2019 Aug 22. PMID: 31290716. 41: Azad TD, Varshneya K, Ho AL, Veeravagu A, Sciubba DM, Ratliff JK. Laminectomy Versus Corpectomy for Spinal Metastatic Disease-Complications, Costs, and Quality Outcomes. World Neurosurg. 2019 Nov;131:e468-e473. doi: 10.1016/j.wneu. 2019.07.206. Epub 2019 Aug 9. PMID: 31404695. 42: Samuelsen C, Lim J, Golembesky A, Shrestha S, Wang L, Griebsch I. Healthcare resource utilization and costs associated with patients prescribed afatinib or erlotinib as first-line therapy for EGFR mutation-positive NSCLC in the United States. J Med Econ. 2020 Jan;23(1):48-53. doi: 10.1080/13696998.2019.1645681. Epub 2019 Aug 9. PMID: 31314630.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

43: Lee I, Adimadhyam S, Nutescu EA, Zhou J, Asfaw AA, Sweiss KI, Patel PR, Calip GS. Bevacizumab Use and the Risk of Arterial and Venous Thromboembolism in Patients with High-Grade Gliomas: A Nested Case-Control Study. Pharmacotherapy. 2019 Sep;39(9):921-928. doi: 10.1002/phar.2310. Epub 2019 Aug 6. PMID: 31332810; PMCID: PMC7395667. 44: Cai B, Said Q, Li X, Li FY, Arcona S. Healthcare costs and resource utilization in patients with severe aplastic anemia in the US. J Med Econ. 2019 Oct;22(10):1055-1062. doi:10.1080/13696998. 2019. 1643354. Epub 2019 Aug 4. PMID: 31296074. 45: Bonafede MM, Miller JD, Pohlman SK, Troeger KA, Sprague BL, Herschorn SD, Winer IH. Breast, Cervical, and Colorectal Cancer Screening: Patterns Among Women With Medicaid and Commercial Insurance. Am J Prev Med. 2019 Sep;57(3):394-402. doi:10.1016/ j.amepre.2019.04.010. Epub 2019 Aug 1. PMID: 31377088; PMCID: PMC7433028. 46: Sharma M, Ugiliweneza B, Boakye M, Andaluz N, Williams BJ. Feasibility of Bundled Payments in Anterior, Middle, and Posterior Cranial Fossa Skull Base Meningioma Surgery: MarketScan Analysis of Health Care Utilization and Outcomes. World Neurosurg. 2019 Nov;131:e116-e127. doi:10.1016/ j.wneu. 2019.07.078. Epub 2019 Jul 16. PMID: 31323403. 47: Lutsey PL, Walker RF, MacLehose RF, Alonso A, Adam TJ, Zakai NA. Direct oral anticoagulants and warfarin for venous thromboembolism treatment: Trends from 2012 to 2017. Res Pract Thromb Haemost. 2019 Jun 9;3(4):668-673. doi:10.1002/ rth2.12222. PMID: 31624786; PMCID: PMC6782014. 48: Pal S, Gong J, Mhatre SK, Lin SW, Surinach A, Ogale S, Vohra R, Wallen H, George D. Real-world treatment patterns and adverse events in metastatic renal cell carcinoma from a large US claims database. BMC Cancer. 2019 Jun 7;19(1):548. doi:10.1186/ s12885-019-5716-z. PMID: 31174493; PMCID: PMC6555983. 49: Sears ED, Lu YT, Chung TT, Momoh AO, Chung KC. Pathology Evaluation of Reduction Mammaplasty Specimens and Subsequent Diagnosis of Malignant Breast Disease: A Claims-Based Analysis. World J Surg. 2019 Jun;43(6):1546-1553. doi:10.1007/s00268-019-04931-1. PMID: 30719555; PMCID: PMC7422755. 50: Ghate S, I onescu-Ittu R, Burne R, Ndife B, Laliberté F, Nakasato A, Duh MS. Patterns of treatment and BRAF testing with immune checkpoint inhibitors and targeted therapy in patients with metastatic melanoma presumed to be BRAF positive. Melanoma Res. 2019 Jun;29(3):301-310. doi:10.1097/CMR. 0000000000000504. PMID: 30247203; PMCID: PMC6494034. 51: Song X, El Khoury AC, Brouillette M, Smith D, Joshi K. Treatment discontinuation of long-acting injectables or oral atypical antipsychotics among Medicaid recipients with schizophrenia. J Med Econ. 2019 Nov;22(11):1105-1112. doi: 10.1080/13696998.2019.1615927. Epub 2019 May 23. PMID: 31062998.

52: Harrison RF, He W, Fu S, Zhao H, Sun CC, Suidan RS, Woodard TL, Rauh-Hain JA, Westin SN, Giordano SH, Meyer LA. National patterns of care and fertility outcomes for reproductive-aged women with endometrial cancer or atypical hyperplasia. Am J Obstet Gynecol. 2019 Nov;221(5):474.e1-474.e11. doi:10.1016/ j.ajog.2019.05.029. Epub 2019 May 22. PMID: 31128110; PMCID: PMC7069241. 53: Selter J, Huang Y, Grossman Becht LC, Palmerola KL, Williams SZ, Forman E, Ananth CV, Hur C, Neugut AI, Hershman DL, Wright JD. Use of fertility preservation services in female reproductive-aged cancer patients. Am J Obstet Gynecol. 2019 Oct;221(4): 328.e1-328.e16. doi: 10.1016/j.ajog.2019.05.009. Epub 2019 May 18. PMID: 31108063. 54: Woods GM, Boulet SL, Texter K, Yates AR, Kerlin BA. Venous thromboembolism in chronic pediatric heart disease is associated with substantial health care burden and expenditures. Res Pract Thromb Haemost. 2019 May 17;3(3):372-382. doi: 10.1002/ rth2.12205. PMID: 31294324; PMCID: PMC6611372. 55: Hagiwara M, Panjabi S, Sharma A, Delea TE. Healthcare utilization and costs among relapsed or refractory multiple myeloma patients on carfilzomib or pomalidomide as monotherapy or in combination with dexamethasone. J Med Econ. 2019 Aug;22(8):818-829. doi: 10.1080/13696998.2019.1614932. Epub 2019 May 17. PMID: 31046501. 56: Neuner JM, Nattinger AB, Yen T, McGinley E, Nattinger M, Pezzin LE. Temporal trends and regional variation in the utilization of low-value breast cancer care: has the Choosing Wisely campaign made a difference? Breast Cancer Res Treat. 2019 Jul;176(1): 205-215. doi: 10.1007/s10549-019-05213-z. Epub 2019 Apr 10. PMID: 30972612; PMCID: PMC6687306. 57: Suidan RS, He W, Sun CC, Zhao H, Rauh-Hain JA, Fleming ND, Lu KH, Giordano SH, Meyer LA. Total and out-of-pocket costs of different primary management strategies in ovarian cancer. Am J Obstet Gynecol. 2019 Aug;221(2):136.e1-136.e9. doi:10.1016/ j.ajog.2019.04.005. Epub 2019 Apr 6. PMID: 30965052; PMCID: PMC7392324. 58: Hess LM, Zhu YE, Sugihara T, Fang Y, Collins N, Nicol S. Challenges of Using ICD-9-CM and ICD-10-CM Codes for Soft-Tissue Sarcoma in Databases for Health Services Research. Perspect Health Inf Manag. 2019 Apr 1;16(Spring):1a. PMID: 31019431; PMCID: PMC6462881. 59: Lee JH, Ba D, Liu G, Leslie D, Zacharia BE, Goyal N. Association of Head and Neck Cancer With Mental Health Disorders in a Large Insurance Claims Database. JAMA Otolaryngol Head Neck Surg. 2019 Apr 1;145(4):339-344. doi:10.1001/jamaoto.2018.4512. PMID: 30816930; PMCID: PMC6481424. 60: Montastruc F, Renoux C, Dell'Aniello S, Simon TA, Azoulay L, Hudson M, Suissa S. Abatacept initiation in rheumatoid arthritis and the risk of cancer: a population-based comparative cohort study. Rheumatology (Oxford). 2019 Apr 1;58(4):683-691. doi: 10.1093/rheumatology/key352. PMID: 30535094; PMCID: PMC6434371.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

61: Lutsey PL, Zakai NA, MacLehose RF, Norby FL, Walker RF, Roetker NS, Adam TJ, Alonso A. Risk of hospitalised bleeding in comparisons of oral anticoagulant options for the primary treatment of venous thromboembolism. Br J Haematol. 2019 Jun;185(5):903-911. doi: 10.1111/bjh.15857. Epub 2019 Mar 28. PMID: 30919942; PMCID: PMC6536346. 62: Ling YL, Huang X, Mitri G, Lovelace B, Pham A, Knobler R, Li X, Gao X. Real- world use of extracorporeal photopheresis for patients with cutaneous T-cell lymphoma in the United States: 2010-2015. J Dermatolog Treat. 2020 Feb;31(1):91-98. doi:10.1080/09546634. 2019.1587144. Epub 2019 Mar 28. PMID: 30892982. 63: Mahendraratnam N, Farley JF, Basch E, Proctor A, Wheeler SB, Dusetzina SB. Characterizing and assessing antiemetic underuse in patients initiating highly emetogenic chemotherapy. Support Care Cancer. 2019 Dec;27(12):4525-4534. doi:10.1007/s00520-019-04730-3. Epub 2019 Mar 26. PMID: 30915567. 64: Ren J, Asche CV, Shou Y, Galaznik A. Economic burden and treatment patterns for patients with diffuse large B-cell lymphoma and follicular lymphoma in the USA. J Comp Eff Res. 2019 Apr;8(6):393-402. doi: 10.2217/cer-2018-0094. Epub 2019 Mar 11. PMID: 30855175. 65: Kim SC, Pawar A, Desai RJ, Solomon DH, Gale S, Bao M, Sarsour K, Schneeweiss S. Risk of malignancy associated with use of tocilizumab versus other biologics in patients with rheumatoid arthritis: A multi-database cohort study. Semin Arthritis Rheum. 2019 Oct;49(2):222-228. doi: 10.1016/j.semarthrit.2019.03.002. Epub 2019 Mar 9. PMID: 30967248. 66: Purdum A, Tieu R, Reddy SR, Broder MS. Direct Costs Associated with Relapsed Diffuse Large B-Cell Lymphoma Therapies. Oncologist. 2019 Sep;24(9):1229-1236. doi: 10.1634/ theoncologist.2018-0490. Epub 2019 Mar 8. PMID: 30850561; PMCID: PMC6738309. 67: Gordan L, Blazer M, Saundankar V, Kazzaz D, Weidner S, Eaddy M. Cost differential of immuno-oncology therapy delivered at community versus hospital clinics. Am J Manag Care. 2019 Mar 1;25(3):e66-e70. PMID: 30875173. 68: Wen L, Yao J, Valderrama A. Evaluation of Treatment Patterns and Costs in Patients with Prostate Cancer and Bone Metastases. J Manag Care Spec Pharm. 2019 Mar;25(3-b Suppl):S1-S11. doi: 10.18553/jmcp.2019.25.3-b.s1. PMID: 30827188. 69: Huo J, Xu Y, Sheu T, Volk RJ, Shih YT. Complication Rates and Downstream Medical Costs Associated With Invasive Diagnostic Procedures for Lung Abnormalities in the Community Setting. JAMA Intern Med. 2019 Mar 1;179(3):324-332. doi: 10.1001/ jamainternmed.2018.6277. PMID: 30640382; PMCID: PMC6440230. 70: Ward M, Harnett J, Bell TJ, Mardekian J. Risk Factors of QTc Prolongation in Women With Hormone Receptor‒positive/Human Epidermal Growth Factor Receptor 2‒negative Metastatic Breast Cancer: A Retrospective Analysis of Health Care Claims Data. Clin Ther. 2019 Mar;41(3):494-504.e1. doi: 10.1016/ j.clinthera.2019. 01.012. Epub 2019 Feb 18. PMID: 30792074.

71: Park H, Wang W, Henry L, Nelson DR. Impact of All-Oral Direct-Acting Antivirals on Clinical and Economic Outcomes in Patients With Chronic Hepatitis C in the United States. Hepatology. 2019 Mar;69(3):1032-1045. doi:10.1002/hep.30303. Epub 2019 Feb 10. PMID: 30289989; PMCID: PMC6393174. 72: Patel K, Sudhir VS, Kabadi S, Huang JC, Porwal S, Thakkar K, Pagel JM. Impact of dosing frequency (once daily or twice daily) on patient adherence to oral targeted therapies for hematologic malignancies: a retrospective cohort study among managed care enrollees. J Oncol Pharm Pract. 2019 Dec;25(8):1897-1906. doi: 10.1177/1078155219827637. Epub 2019 Feb 5. PMID: 30823852; PMCID: PMC6839022. 73: Nuño M, Ugiliweneza B, Boakye M, Monfared A. Morbidity of Vestibular Schwannomas as Documented by Treating Providers. Otol Neurotol. 2019 Feb;40(2):e142-e149. doi: 10.1097/ MAO.0000000000002099. PMID: 30624406. 74: Lairson DR, Wu CF, Chan W, Fu S, Hoffman KE, Pettaway CA. Mean treatment cost of incident cases of penile cancer for privately insured patients in the United States. Urol Oncol. 2019 Apr;37 (4):294.e17-294.e25. doi:10.1016/j.urolonc.2019.01.004. Epub 2019 Jan 17. PMID: 30660492. 75: Song X, Said Q, Tran O, Krueger DA, Bissler J. Everolimus compliance and persistence among tuberous sclerosis complex patients with renal angiomyolipoma or subependymal giant cell astrocytoma. Curr Med Res Opin. 2019 Jun;35(6):1103-1110. doi: 10.1080/03007995.2018.1558883. Epub 2019 Jan 14. PMID: 30550347. 76: Zhou J, Han J, Nutescu EA, Patel PR, Sweiss K, Calip GS. Discontinuation and Nonadherence to Medications for Chronic Conditions after Hematopoietic Cell Transplantation: A 6-Year Propensity Score-Matched Cohort Study. Pharmacotherapy. 2019 Jan;39(1):55-66. doi: 10.1002/phar.2197. Epub 2019 Jan 4. PMID: 30485471. 77: Cerullo M, Gani F, Chen SY, Canner JK, Dillhoff M, Cloyd J, Pawlik TM. Routine intensive care unit admission among patients undergoing major pancreatic surgery for cancer: No effect on failure to rescue. Surgery. 2019 Apr;165(4):741-746. doi: 10.1016/j.surg.2018.11.005. Epub 2018 Dec 11. PMID: 30551866. 78: Lutsey PL, Norby FL, Zakai NA, MacLehose RF, Chen LY, Shah S, Datta YH, Alonso A. Oral anticoagulation therapy and subsequent risk of venous thromboembolism in atrial fibrillation patients. Curr Med Res Opin. 2019 May;35(5):837-845. doi:10.1080/03007995. 2018.1541445. Epub 2018 Dec 3. PMID: 30362847; PMCID: PMC6449182. 79: Bhowmik D, Song X, Intorcia M, Gray S, Shi N. Examination of burden of skeletal-related events in patients naive to denosumab and intravenous bisphosphonate therapy in bone metastases from solid tumors population. Curr Med Res Opin. 2019 Mar;35(3):513-523. doi: 10.1080/03007995.2018.1532884. Epub 2018 Nov 20. PMID: 30286662.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

80: Kundrick A, Kirby J, Ba D, Leslie D, Olsen N, Foulke G. Positron emission tomography costs less to patients than conventional screening for malignancy in dermatomyositis. Semin Arthritis Rheum. 2019 Aug;49(1):140-144. doi:10.1016/j.semarthrit. 2018.10.021. Epub 2018 Nov 2. PMID: 30482435. 81: Basak R, Bentley JP, McCaffrey DJ 3rd, West-Strum D, Przybyla SM, Banahan BF 3rd. Comparing algorithms for composite measures of intra-disease multiple medication adherence: The case of diabetes. Res Social Adm Pharm. 2019 Sep;15(9):1160-1167. doi:10.1016/ j.sapharm.2018.09.024. Epub 2018 Oct 2. PMID: 30301682. 82: Shao C, Liu J, Zhou W, Raut MK, Monberg M, Cao X, Ricart AD, Balakumaran A. Treatment patterns, health care resource utilization, and costs in patients with relapsed/refractory Hodgkin lymphoma treated with brentuximab vedotin. Leuk Lymphoma. 2019 Apr;60(4): 947-954. doi:10.1080/10428194. 2018. 1508665. Epub 2018 Sep 20. PMID: 30234407. 83: Princic N, Aizer A, Tang DH, Smith DM, Johnson W, Bardia A. Predictors of systemic therapy sequences following a CDK 4/6 inhibitor-based regimen in post-menopausal women with hormone receptor positive, HEGFR-2 negative metastatic breast cancer. Curr Med Res Opin. 2019 Jan;35(1):73-80. doi:10.1080/03007995. 2018.1519500. Epub 2018 Sep 20. PMID: 30175631. 84: Jabbour EJ, Siegartel LR, Lin J, Lingohr-Smith M, Menges B, Makenbaeva D. Impact of earlier versus later monitoring on disease progression and healthcare costs among patients with chronic myeloid leukemia in the United States. Leuk Lymphoma. 2019 Mar;60(3):668-674. doi:10.1080/10428194.2018. 1492124. Epub 2018 Aug 20. PMID: 30124372. 85: Fisher AV, Fernandes-Taylor S, Schumacher JR, Havlena JA, Wang X, Lawson EH, Ronnekleiv-Kelly SM, Winslow ER, Weber SM, Abbott DE. Analysis of 90-day cost for open versus minimally invasive distal pancreatectomy. HPB (Oxford). 2019 Jan;21(1):60-66. doi:10.1016/ j.hpb.2018.07.003. Epub 2018 Jul 31. PMID: 30076011. 86: Bhowmik D, Song X, Intorcia M, Kent ST, Shi N. Healthcare resource use and costs associated with chronic kidney disease in US private insurance patients with multiple myeloma. J Oncol Pharm Pract. 2019 Jun;25(4):855-864. doi:10.1177/ 1078155218766408. Epub 2018 Apr 16. PMID: 29661050.

Cardiovascular 1: Assimon MM, Wang L, Pun PH, Winkelmayer WC, Flythe JE. Use of QT Prolonging Medications by Hemodialysis Patients and Individuals Without End-Stage Kidney Disease. J Am Heart Assoc. 2020 Jul 7;9 (13):e015969. doi: 10.1161/JAHA.120.015969. Epub 2020 Jun 24. PMID: 32578475. 2: Zhang H, Dahlén T, Khan A, Edgren G, Rzhetsky A. Measurable health effects associated with the daylight saving time shift. PLoS Comput Biol. 2020 Jun 8;16(6):e1007927. doi:10.1371/ journal. pcbi.1007927. PMID: 32511231; PMCID: PMC7302868.

3: Rosenbloom JI, Stwalley D, Lindley KJ, Michael Nelson D, Olsen MA, Stout MJ. Latency of preterm hypertensive disorders of pregnancy and subsequent cardiovascular complications. Pregnancy Hypertens. 2020 Jul;21:139-144. doi: 10.1016/ j.preghy.2020.05.015. Epub 2020 May 31. PMID: 32516748. 4: Cork DP, McCullough PA, Mehta HS, Barker CM, Gunnarsson C, Ryan MP, Baker ER, Van Houten J, Mollenkopf S, Verta P. Impact of mitral regurgitation on cardiovascular hospitalization and death in newly diagnosed heart failure patients. ESC Heart Fail. 2020 Aug;7(4):1502-1509. doi: 10.1002/ehf2.12653. Epub 2020 May 29. PMID: 32469120; PMCID: PMC7373926. 5: Reddy SR, Chang E, Tarbox MH, Broder MS, Tieu RS, Guthrie S, Vera-Llonch M, Pollock MR. The Clinical and Economic Burden of Newly Diagnosed Hereditary Transthyretin (ATTRv) Amyloidosis: A Retrospective Analysis of Claims Data. Neurol Ther. 2020 May 25. doi: 10.1007/s40120-020-00194-4. Epub ahead of print. PMID: 32451849. 6: Chen N, Alam AB, Lutsey PL, MacLehose RF, Claxton JS, Chen LY, Chamberlain AM, Alonso A. Polypharmacy, Adverse Outcomes, and Treatment Effectiveness in Patients ≥75 With Atrial Fibrillation. J Am Heart Assoc. 2020 Jun 2;9(11):e015089. doi: 10.1161/ JAHA.119.015089. Epub 2020 May 23. PMID: 32448024; PMCID: PMC7429010. 7: Yong CM, Tremmel JA, Lansberg MG, Fan J, Askari M, Turakhia MP. Sex Differences in Oral Anticoagulation and Outcomes of Stroke and Intracranial Bleeding in Newly Diagnosed Atrial Fibrillation. J Am Heart Assoc. 2020 May 18;9(10):e015689. doi: 10.1161/JAHA.120.015689. Epub 2020 May 12. PMID: 32394763. 8: Tonna JE, Hanson HA, Cohan JN, McCrum ML, Horns JJ, Brooke BS, Das R, Kelly BC, Campbell AJ, Hotaling J. Balancing revenue generation with capacity generation: Case distribution, financial impact and hospital capacity changes from cancelling or resuming elective surgeries in the US during COVID-19. medRxiv [Preprint]. 2020 May 4:2020.04.29.20066506. doi: 10.1101/2020. 04.29. 20066506. PMID: 32511614; PMCID: PMC7276041. 9: Rymer JA, Mues KE, Monda KL, Bratton EW, Wirtz HS, Okerson T, Overman RA, Brookhart MA, Muntner P, Wang TY. Use of Low-Density Lipoprotein-Lowering Therapies Before and After PCSK9 Inhibitor Initiation. J Am Heart Assoc. 2020 May 5;9(9):e014347. doi: 10.1161/JAHA.119.014347. Epub 2020 Apr 24. PMID: 32326795; PMCID: PMC7428552. 10: Claxton JS, Chamberlain AM, Lutsey PL, Chen LY, MacLehose RF, Bengtson LGS, Alonso A. Association of Multimorbidity with Cardiovascular Endpoints and Treatment Effectiveness in Patients 75 Years and Older with Atrial Fibrillation. Am J Med. 2020 Apr 19:S0002-9343(20)30344-2. doi:10.1016/j.amjmed. 2020. 03.038. Epub ahead of print. PMID: 32320695. 11: Elharram M, Moura CS, Abrahamowicz M, Bernatsky S, Behlouli H, Raparelli V, Pilote L. Novel glucose lowering agents are associated with a lower risk of cardiovascular and adverse events in type 2 diabetes: A population based analysis. Int J Cardiol. 2020 Jul 1;310:147-154. doi:10.1016/j.ijcard.2020.03.025. Epub 2020 Apr 15. PMID: 32303419.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

12: Burmester GR, Curtis JR, Yun H, FitzGerald O, Winthrop KL, Azevedo VF, Rigby WFC, Kanik KS, Wang C, Biswas P, Jones T, Palmetto N, Hendrikx T, Menon S, Rojo R. An Integrated Analysis of the Safety of Tofacitinib in Psoriatic Arthritis across Phase III and Long-Term Extension Studies with Comparison to Real-World Observational Data. Drug Saf. 2020 Apr;43(4):379-392. doi: 10.1007/s40264-020-00904-9. PMID: 32006348; PMCID: PMC7105422. 13: Miao B, Hernandez AV, Roman YM, Alberts MJ, Coleman CI, Baker WL. Four-year incidence of major adverse cardiovascular events in patients with atherosclerosis and atrial fibrillation. Clin Cardiol. 2020 May;43(5):524-531. doi: 10.1002/clc.23344. Epub 2020 Feb 27. PMID: 32106334; PMCID: PMC7244295. 14: Miao B, Hernandez AV, Alberts MJ, Mangiafico N, Roman YM, Coleman CI. Incidence and Predictors of Major Adverse Cardiovascular Events in Patients With Established Atherosclerotic Disease or Multiple Risk Factors. J Am Heart Assoc. 2020 Jan 21; 9 (2):e014402. doi: 10.1161/JAHA.119.014402. Epub 2020 Jan 15. PMID: 31937196; PMCID: PMC7033849. 15: Raparelli V, Elharram M, Moura CS, Abrahamowicz M, Bernatsky S, Behlouli H, Pilote L. Sex Differences in Cardiovascular Effectiveness of Newer Glucose-Lowering Drugs Added to Metformin in Type 2 Diabetes Mellitus. J Am Heart Assoc. 2020 Jan 7;9(1):e012940. doi: 10.1161/JAHA.119.012940. Epub 2020 Jan 4. PMID: 31902326; PMCID: PMC6988160. 16: Field ME, Gold MR, Reynolds MR, Goldstein L, Lee SHY, Kalsekar I, Coplan P, Wong C, Khanna R, Winterfield JR. Real-world outcomes of ventricular tachycardia catheter ablation with versus without intracardiac echocardiography. J Cardiovasc Electrophysiol. 2020 Feb;31(2):417-422. doi: 10.1111/jce.14324. Epub 2019 Dec 27. PMID: 31868258. 17: Chen YW, Voelker J, Tunceli O, Pericone CD, Bookhart B, Durkin M. Real-world comparison of hospitalization costs for heart failure in type 2 diabetes mellitus patients with established cardiovascular disease treated with canagliflozin versus other antihyperglycemic agents. J Med Econ. 2020 Apr;23(4):401-406. doi:10.1080/13696998.2019. 1693384. Epub 2019 Dec 4. PMID: 31801393. 18: Alrwisan AA, Wei YJ, Brumback BA, Antonelli PJ, Winterstein AG. Concomitant Use of Quinolones and Stimulants and the Risk of Adverse Cardiovascular Symptoms: A Retrospective Cohort Study. Pharmacotherapy. 2019 Dec;39(12):1167-1178. doi:10.1002/ phar.2343. Epub 2019 Nov 25. PMID: 31674031. 19: Bangalore S, Shah R, Gao X, Pappadopulos E, Deshpande CG, Shelbaya A, Prieto R, Stephens J, Chambers R, Schepman P, McIntyre RS. Economic burden associated with inadequate antidepressant medication management among patients with depression and known cardiovascular diseases: insights from a United States-based retrospective claims database analysis. J Med Econ. 2020 Mar;23(3): 262-270. doi:10.1080/13696998. 2019.1686311. Epub 2019 Nov 22. PMID: 31665949.

20: Colantonio LD, Shannon ED, Orroth KK, Zaha R, Jackson EA, Rosenson RS, Exter J, Mues KE, Muntner P. Ischemic Event Rates in Very-High-Risk Adults. J Am Coll Cardiol. 2019 Nov 19;74 (20): 2496-2507. doi: 10.1016/j.jacc.2019.09.025. PMID: 31727288. 21: Ogilvie RP, MacLehose RF, Alonso A, Norby FL, Lakshminarayan K, Iber C, Chen LY, Lutsey PL. Diagnosed Sleep Apnea and Cardiovascular Disease in Atrial Fibrillation Patients: The Role of Measurement Error from Administrative Data. Epidemiology. 2019 Nov;30(6):885-892. doi: 10.1097/EDE.0000000000001049. PMID: 31205284. 22: Mansour M, Reddy VY, Karst E, Heist EK, Packer DL, Dalal N, Agarwal R, Calkins H, Ruskin JN, Mahapatra S. Economic impact of contact force sensing in catheter ablation for atrial fibrillation. J Cardiovasc Electrophysiol. 2019 Nov;30(11):2302-2309. doi: 10.1111/jce.14189. Epub 2019 Oct 3. PMID: 31549456. 23: Agarwal A, Thombley R, Broberg CS, Harris IS, Foster E, Mahadevan VS, John A, Vittinghoff E, Marcus GM, Dudley RA. Age- and Lesion-Related Comorbidity Burden Among US Adults With Congenital Heart Disease: A Population-Based Study. J Am Heart Assoc. 2019 Oct 15;8(20):e013450. doi:10.1161/JAHA.119. 013450. Epub 2019 Oct 2. PMID: 31575318; PMCID: PMC6818026. 24: Wetmore JB, Li S, Ton TGN, Peng Y, Hansen MK, Neslusan C, Riley R, Liu J, Gilbertson DT. Association of diabetes-related kidney disease with cardiovascular and non-cardiovascular outcomes: a retrospective cohort study. BMC Endocr Disord. 2019 Aug 27;19 (1):89. doi: 10.1186/s12902-019-0417-9. PMID: 31455289; PMCID: PMC6712860. 25: Baker-Goering MM, Howard DH, Will JC, Beeler Asay GR, Roy K. Association Between Self-Reported Hypertension and Antihypertensive Medication Use and Cardiovascular Disease-Related Events and Expenditures Among Patients Diagnosed With Hypertension. Public Health Rep. 2019 Sep/Oct;134(5):493-501. doi:10.1177/0033354919864363. Epub 2019 Aug 12. PMID: 31404507; PMCID: PMC6852063. 26: Zhuang S, Na M, Winkelman JW, Ba D, Liu CF, Liu G, Gao X. Association of Restless Legs Syndrome With Risk of Suicide and Self-harm. JAMA Netw Open. 2019 Aug 2;2(8):e199966. doi: 10.1001/jamanetworkopen.2019.9966. PMID: 31441941; PMCID: PMC6714009. 27: Xie F, Yun H, Levitan EB, Muntner P, Curtis JR. Tocilizumab and the Risk of Cardiovascular Disease: Direct Comparison Among Biologic Disease-Modifying Antirheumatic Drugs for Rheumatoid Arthritis Patients. Arthritis Care Res (Hoboken). 2019 Aug;71(8): 1004-1018. doi: 10.1002/acr.23737. PMID: 30175897. 28: Alonso A, Barnes AE, Guest JL, Shah A, Shao IY, Marconi V. HIV Infection and Incidence of Cardiovascular Diseases: An Analysis of a Large Healthcare Database. J Am Heart Assoc. 2019 Jul 16;8 (14):e012241. doi:10.1161/JAHA.119.012241. Epub 2019 Jul 2. PMID: 31266386; PMCID: PMC6662120.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

29: Baker WL, Beyer-Westendorf J, Bunz TJ, Eriksson D, Meinecke AK, Sood NA, Coleman CI. Effectiveness and safety of rivaroxaban and warfarin for prevention of major adverse cardiovascular or limb events in patients with non-valvular atrial fibrillation and type 2 diabetes. Diabetes Obes Metab. 2019 Sep;21(9):2107-2114. doi:10.1111/ dom.13787. Epub 2019 Jun 11. PMID: 31099460. 30: Lee MP, Desai RJ, Jin Y, Brill G, Ogdie A, Kim SC. Association of Ustekinumab vs TNF Inhibitor Therapy With Risk of Atrial Fibrillation and Cardiovascular Events in Patients With Psoriasis or Psoriatic Arthritis. JAMA Dermatol. 2019 Jun 1;155(6):700-707. doi:10.1001/ jamadermatol.2019.0001. PMID: 30916734; PMCID: PMC6563547. 31: Tajeu GS, Kent ST, Huang L, Bress AP, Cuffee Y, Halpern MT, Kronish IM, Krousel-Wood M, Mefford MT, Shimbo D, Muntner P. Antihypertensive Medication Nonpersistence and Low Adherence for Adults <65 Years Initiating Treatment in 2007-2014. Hypertension. 2019 Jul;74(1):35-46. doi:10.1161/HYPERTENSIONAHA.118.12495. Epub 2019 May 28. PMID: 31132956; PMCID: PMC6914333. 32: Woods GM, Boulet SL, Texter K, Yates AR, Kerlin BA. Venous thromboembolism in chronic pediatric heart disease is associated with substantial health care burden and expenditures. Res Pract Thromb Haemost. 2019 May 17;3(3):372-382. doi: 10.1002/ rth2. 12205. PMID: 31294324; PMCID: PMC6611372. 33: Malhamé I, Dayan N, Moura CS, Samuel M, Vinet E, Pilote L. Peripartum cardiomyopathy with co-incident preeclampsia: A cohort study of clinical risk factors and outcomes among commercially insured women. Pregnancy Hypertens. 2019 Jul;17:82-88. doi: 10.1016/j.preghy.2019.05.014. Epub 2019 May 9. PMID: 31487662. 34: Bloom L, Boyle KE, Myers AE, Blacketer C, Weinstein R. Frequency of nonaspirin NSAID-relevant coexisting medical conditions in the primary-care setting: a retrospective database review. Ther Clin Risk Manag. 2019 Apr 24;15:579-588. doi: 10.2147/TCRM.S189833. PMID: 31114212; PMCID: PMC6488163. 35: Chung AY, Strassle PD, Schlottmann F, Patti MG, Duke MC, Farrell TM. Trends in Utilization and Relative Complication Rates of Bariatric Procedures. J Gastrointest Surg. 2019 Jul;23(7):1362-1372. doi: 10.1007/s11605-018-3951-2. Epub 2019 Apr 22. PMID: 31012048. 36: Bicket MC, Murimi IB, Mansour O, Wu CL, Alexander GC. Association of new opioid continuation with surgical specialty and type in the United States. Am J Surg. 2019 Nov;218(5):818-827. doi: 10.1016/j.amjsurg.2019.04.010. Epub 2019 Apr 15. PMID: 31023548. 37: Navar AM, Peterson ED, Steen DL, Wojdyla DM, Sanchez RJ, Khan I, Song X, Gold ME, Pencina MJ. Evaluation of Mortality Data From the Social Security Administration Death Master File for Clinical Research. JAMA Cardiol. 2019 Apr 1;4(4):375-379. doi: 10.1001/jamacardio. 2019.0198. PMID: 30840023; PMCID: PMC6484792.

38: Sparks JA, Lesperance T, Accortt NA, Solomon DH. Subsequent Cardiovascular Events Among Patients With Rheumatoid Arthritis, Psoriatic Arthritis, or Psoriasis: Patterns of Disease-Modifying Antirheumatic Drug Treatment. Arthritis Care Res (Hoboken). 2019 Apr;71(4):512-520. doi: 10.1002/acr.23609. PMID: 29799667; PMCID: PMC6252288. 39: Pham PN, Brown JD. Real-world adherence for direct oral anticoagulants in a newly diagnosed atrial fibrillation cohort: does the dosing interval matter? BMC Cardiovasc Disord. 2019 Mar 19;19(1):64. doi: 10.1186/s12872-019-1033-3. PMID: 30890131; PMCID: PMC6423818. 40: Desai RJ, Sarpatwari A, Dejene S, Khan NF, Lii J, Rogers JR, Dutcher SK, Raofi S, Bohn J, Connolly JG, Fischer MA, Kesselheim AS, Gagne JJ. Comparative effectiveness of generic and brand-name medication use: A database study of US health insurance claims. PLoS Med. 2019 Mar 13;16(3):e1002763. doi:10.1371/ journal.pmed.1002763. PMID: 30865626; PMCID: PMC6415809. 41: Ward M, Harnett J, Bell TJ, Mardekian J. Risk Factors of QTc Prolongation in Women With Hormone Receptor‒positive/Human Epidermal Growth Factor Receptor 2‒negative Metastatic Breast Cancer: A Retrospective Analysis of Health Care Claims Data. Clin Ther. 2019 Mar;41(3):494-504.e1. doi:10.1016/j.clinthera. 2019. 01.012. Epub 2019 Feb 18. PMID: 30792074. 42: Alvarez PA, Truong CN, Briasoulis A, Ganduglia-Cazaban C. Prescription of Potentially Harmful Drugs in Young Adults With Heart Failure and Reduced Ejection Fraction. Am J Cardiol. 2019 May 1;123(9):1458-1463. doi:10.1016/j.amjcard.2019.01.052. Epub 2019 Feb 10. PMID: 30791999. 43: Martinez AI, Freeman PR, Moga DC. Statin Use and Gastrointestinal Hemorrhage: A Large Retrospective Cohort Study. Am J Cardiovasc Drugs. 2019 Feb;19(1):65-74. doi: 10.1007/ s40256-018-0301-4. PMID: 30255477. 44: Ritchey ME, Harding A, Hunter S, Peterson C, Sager PT, Kowey PR, Nguyen L, Thomas S, Cainzos-Achirica M, Rothman KJ, Andrews EB, Anthony MS. Cardiovascular Safety During and After Use of Phentermine and Topiramate. J Clin Endocrinol Metab. 2019 Feb 1;104(2):513-522. doi: 10.1210/jc.2018-01010. PMID: 30247575; PMCID: PMC6318778. 45: Colantonio LD, Rosenson RS, Deng L, Monda KL, Dai Y, Farkouh ME, Safford MM, Philip K, Mues KE, Muntner P. Adherence to Statin Therapy Among US Adults Between 2007 and 2014. J Am Heart Assoc. 2019 Jan 8;8(1):e010376. doi:10.1161/JAHA.118. 010376. PMID: 30616455; PMCID: PMC6405715. 46: Guo J, Nayak HM, Besser SA, Beaser A, Aziz Z, Broman M, Ozcan C, Tung R, Upadhyay GA. Impact of Atrial Fibrillation Ablation on Recurrent Hospitalization: A Nationwide Cohort Study. JACC Clin Electrophysiol. 2019 Mar;5(3):330-339. doi: 10.1016/ j.jacep.2018.10.015. Epub 2018 Dec 26. PMID: 30898236.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

47: Claxton JS, Lutsey PL, MacLehose RF, Chen LY, Lewis TT, Alonso A. Geographic Disparities in the Incidence of Stroke among Patients with Atrial Fibrillation in the United States. J Stroke Cerebrovasc Dis. 2019 Apr;28(4):890-899. doi:10.1016/j.jstrokecerebrovasdis.2018.12.005. Epub 2018 Dec 21. PMID: 30583824; PMCID: PMC6475902. 48: Rosenson RS, Colantonio LD, Burkholder GA, Chen L, Muntner P. Trends in Utilization of Statin Therapy and Contraindicated Statin Use in HIV—Infected Adults Treated With Antiretroviral Therapy From 2007 Through 2015. J Am Heart Assoc. 2018 Dec 18;7(24):e010345. doi: 10.1161/JAHA.118.010345. PMID: 30526249; PMCID: PMC6405602. 49: Claxton JS, MacLehose RF, Lutsey PL, Norby FL, Chen LY, O'Neal WT, Chamberlain AM, Bengtson LGS, Alonso A. A new model to predict ischemic stroke in patients with atrial fibrillation using warfarin or direct oral anticoagulants. Heart Rhythm. 2019 Jun;16(6):820-826. doi:10.1016/j.hrthm.2018.12.005. Epub 2018 Dec 12. PMID: 30550837; PMCID: PMC6545238. 50: Lutsey PL, Norby FL, Zakai NA, MacLehose RF, Chen LY, Shah S, Datta YH, Alonso A. Oral anticoagulation therapy and subsequent risk of venous thromboembolism in atrial fibrillation patients. Curr Med Res Opin. 2019 May;35(5):837-845. doi:10.1080/03007995. 2018.1541445. Epub 2018 Dec 3. PMID: 30362847; PMCID: PMC6449182. 51: Cohen B, Balcells C, Hotchkiss B, Aggarwal K, Karaa A. A retrospective analysis of health care utilization for patients with mitochondrial disease in the United States: 2008-2015. Orphanet J Rare Dis. 2018 Nov 22;13(1):210. doi:10.1186/s13023-018-0949-5. PMID: 30466460; PMCID: PMC6251171. 52: Shrestha SS, Zhang P, Hora IA, Gregg EW. Trajectory of Excess Medical Expenditures 10 Years Before and After Diabetes Diagnosis Among U.S. Adults Aged 25-64 Years, 2001-2013. Diabetes Care. 2019 Jan;42(1):62-68. doi:10.2337/dc17-2683. Epub 2018 Nov 19. PMID: 30455325; PMCID: PMC6393199. 53: Morton JM, Ponce J, Malangone-Monaco E, Nguyen N. Association of Bariatric Surgery and National Medication Use. J Am Coll Surg. 2019 Feb;228(2):171-179. doi: 10.1016/j.jamcollsurg. 2018.10.021. Epub 2018 Nov 17. PMID: 30453056.

Respiratory 1: Lenert A, Oh G, Ombrello MJ, Kim S. Clinical characteristics and comorbidities in adult-onset Still's disease using a large US administrative claims database. Rheumatology (Oxford). 2020 Jul 1;59(7):1725-1733. doi:10.1093/rheumatology/kez622. PMID: 31965185; PMCID: PMC7310096. 2: Tran TN, MacLachlan S, Hicks W, Liu J, Chung Y, Zangrilli J, Rubino A, Ganz ML. Oral Corticosteroid Treatment Patterns of Patients in the United States with Persistent Asthma. J Allergy Clin Immunol Pract. 2020 Jun 20:S2213-2198(20)30618-8. doi:10.1016/j.jaip. 2020. 06 019 Epub ahead of print PMID: 32569754

3: Truta B, Leeds IL, Canner JK, Efron JE, Fang SH, Althumari A, Safar B. Early Discontinuation of Infliximab in Pregnant Women With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2020 Jun 18;26(7):1110-1117. doi: 10.1093/ibd/izz250. PMID: 31670762. 4: McCoul ED, Weinreich HM, Mulder H, Man LX, Schulz K, Shin JJ. Utilization of Invasive Procedures for Adult Eustachian Tube Dysfunction. Otolaryngol Head Neck Surg. 2020 Jun 11: 194599820931467. doi: 10.1177/0194599820931467. Epub ahead of print. PMID: 32525448. 5: Patel M, Chen J, Kim S, Garg S, Flannery B, Haddadin Z, Rankin D, Halasa N, Talbot HK, Reed C. Analysis of MarketScan Data for Immunosuppressive Conditions and Hospitalizations for Acute Respiratory Illness, United States. Emerg Infect Dis. 2020 Aug;26 (8):1720-1730. doi: 10.3201/eid2608.191493. Epub 2020 Apr 29. PMID: 32348234; PMCID: PMC7392442. 6: Goldstein M, Krilov LR, Fergie J, Brannman L, Wade SW, Kong AM, Ambrose CS. Unintended Consequences Following the 2014 American Academy of Pediatrics Policy Change for Palivizumab Prophylaxis among Infants Born at Less than 29 Weeks' Gestation. Am J Perinatol. 2020 Apr 16. doi: 10.1055/s-0040-1709127. Epub ahead of print. PMID: 32299107. 7: Hudson M, Dell'Aniello S, Shen S, Simon TA, Ernst P, Suissa S. Comparative safety of biologic versus conventional synthetic DMARDs in rheumatoid arthritis with COPD: a real-world population study. Rheumatology (Oxford). 2020 Apr 1;59(4):820-827. doi: 10.1093/rheumatology/kez359. PMID: 31504972; PMCID: PMC7188346. 8: Lin KJ, Dvorin E, Kesselheim AS. Prescribing systemic steroids for acute respiratory tract infections in United States outpatient settings: A nationwide population-based cohort study. PLoS Med. 2020 Mar 31;17(3):e1003058. doi:10.1371/journal.pmed. 1003058. PMID: 32231363; PMCID: PMC7108689. 9: Simões EAF, Chirikov V, Botteman M, Kwon Y, Kuznik A. Long-term Assessment of Healthcare Utilization 5 Years After Respiratory Syncytial Virus Infection in US Infants. J Infect Dis. 2020 Mar 28;221(8):1256-1270. doi: 10.1093/infdis/jiz278. PMID: 31165865. 10: Chirikov VV, Simões EAF, Kuznik A, Kwon Y, Botteman M. Economic-Burden Trajectories in Commercially Insured US Infants With Respiratory Syncytial Virus Infection. J Infect Dis. 2020 Mar 28;221(8):1244-1255. doi:10.1093/infdis/jiz160. PMID: 30982895. 11: Gold LS, Nazareth TA, Yu TC, Fry KR, Mahler NH, Rava A, Waltrip Ii RW, Hansen RN. Medication Utilization Patterns 90 Days Before Initiation of Treatment with Repository Corticotropin Injection in Patients with Infantile Spasms. Pediatric Health Med Ther. 2019 Dec 31;10:195-207. doi:10.2147/PHMT.S222010. PMID: 32099512; PMCID: PMC6997416. 12: Leung J, Sejvar JJ, Soares J, Lanzieri TM. Guillain-Barré syndrome and antecedent cytomegalovirus infection, USA 2009-2015. Neurol Sci. 2020 Apr;41(4):885-891. doi: 10.1007/s10072-019-04156-z. Epub 2019 Dec 11. PMID: 31828680.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

13: Roland LT, Nagy C, Wang H, Moore R, Cahill KN, Laidlaw TM, Wise SK, DelGaudio JM, Kuruvilla M, Levy JM. Treatment practices for aspirin-exacerbated respiratory disease: analysis of a national insurance claims database. Int Forum Allergy Rhinol. 2020 Feb;10 (2):190-193. doi: 10.1002/alr.22471. Epub 2019 Nov 6. PMID: 31693796; PMCID: PMC7060492. 14: Mejias A, Wu B, Tandon N, Chow W, Varma R, Franco E, Ramilo O. Risk of childhood wheeze and asthma after respiratory syncytial virus infection in full-term infants. Pediatr Allergy Immunol. 2020 Jan;31 (1):47-56. doi:10.1111/pai.13131. Epub 2019 Oct 23. PMID: 31566811. 15: Keshishian A, Xie L, Dembek C, Yuce H. Reduction in Hospital Readmission Rates Among Medicare Beneficiaries With Chronic Obstructive Pulmonary Disease: A Real-world Outcomes Study of Nebulized Bronchodilators. Clin Ther. 2019 Nov;41(11):2283-2296. doi: 10.1016/j.clinthera.2019.09.001. Epub 2019 Oct 17. PMID: 31630815. 16: Settipane RA, Kreindler JL, Chung Y, Tkacz J. Evaluating direct costs and productivity losses of patients with asthma receiving GINA 4/5 therapy in the United States. Ann Allergy Asthma Immunol. 2019 Dec;123(6):564-572.e3. doi:10.1016/j.anai. 2019.08.462. Epub 2019 Sep 6. PMID: 31494235. 17: Ledbetter J, Brannman L, Wade SW, Gonzales T, Kong AM. Healthcare resource utilization and costs in the 12 months following hospitalization for respiratory syncytial virus or unspecified bronchiolitis among infants. J Med Econ. 2020 Feb;23(2):139-147. doi: 10.1080/13696998.2019.1658592. Epub 2019 Sep 4. PMID: 31432723. 18: Carls G, Reddy SR, Broder MS, Tieu R, Villa KF, Profant J, Halbower AC. Burden of disease in pediatric narcolepsy: a claims-based analysis of health care utilization, costs, and comorbidities. Sleep Med. 2020 Feb;66:110-118. doi:10.1016/j.sleep. 2019. 08.008. Epub 2019 Aug 26. PMID: 31841742. 19: Roland LT, Wang H, Mehta CC, Cahill KN, Laidlaw TM, DelGaudio JM, Wise SK, Levy JM. Longitudinal progression of aspirin-exacerbated respiratory disease: analysis of a national insurance claims database. Int Forum Allergy Rhinol. 2019 Dec;9(12):1420-1423. doi: 10.1002/ alr.22412. Epub 2019 Aug 23. PMID: 31442000; PMCID: PMC6901725. 20: Tsai Y, Zhou F, Lindley MC. Insurance Reimbursements for Routinely Recommended Adult Vaccines in the Private Sector. Am J Prev Med. 2019 Aug;57(2):180-190. doi:10.1016/j.amepre.2019.03. 011. Epub 2019 Jun 25. PMID: 31248743; PMCID: PMC6732785. 21: Tsai Y, Lindley MC, Zhou F, Stokley S. Insurance reimbursements for human papillomavirus vaccination in the private sector, 2007-2014. Prev Med Rep. 2019 Jun 7;15:100917. doi:10.1016/j.pmedr. 2019.100917. PMID: 31223560; PMCID: PMC6580314.

22: Amin A, Deitelzweig S, Bucior I, Lin J, Lingohr-Smith M, Menges B, Neuman WR. Frequency of hospital readmissions for venous thromboembolism and associated hospital costs and length of stay among acute medically ill patients in the US. J Med Econ. 2019 Nov;22(11):1119-1125. doi: 10.1080/13696998.2019.1618862. Epub 2019 Jun 4. PMID: 31084383. 23: Suissa S, Hudson M, Dell'Aniello S, Shen S, Simon TA, Ernst P. Comparative safety of abatacept in rheumatoid arthritis with COPD: A real-world population-based observational study. Semin Arthritis Rheum. 2019 Dec;49(3):366-372. doi:10.1016/j.semarthrit. 2019. 03.007. Epub 2019 Mar 16. PMID: 30979397. 24: Zhou F, Xu J, Black CL, Ding H, Cho BH, Lu PJ, Lindley MC. Trends in Tdap vaccination among privately insured pregnant women in the United States, 2009-2016. Vaccine. 2019 Mar 28;37(14):1972-1977. doi:10.1016/j.vaccine.2019.02.042. Epub 2019 Feb 27. PMID: 30826146; PMCID: PMC6557580. 25: Baker JM, Dahl RM, Cubilo J, Parashar UD, Lopman BA. Effects of the rotavirus vaccine program across age groups in the United States: analysis of national claims data, 2001-2016. BMC Infect Dis. 2019 Feb 22;19(1):186. doi:10.1186/s12879-019-3816-7. PMID: 30795739; PMCID: PMC6387516. 26: McCoul ED, Weinreich HM, Mulder H, Man LX, Schulz K, Shin JJ. Health Care Utilization and Prescribing Patterns for Adult Eustachian Tube Dysfunction. Otolaryngol Head Neck Surg. 2019 Jun;160(6):1071-1080. doi:10.1177/0194599819826959. Epub 2019 Feb 5. PMID: 30721112. 27: Llanos JP, Bell CF, Packnett E, Thiel E, Irwin DE, Hahn B, Ortega H. Real- world characteristics and disease burden of patients with asthma prior to treatment initiation with mepolizumab or omalizumab: a retrospective cohort database study. J Asthma Allergy. 2019 Jan 25;12:43-58. doi:10.2147/ JAA.S189676. PMID: 30774390; PMCID: PMC6354698. 28: Montastruc F, Renoux C, Hudson M, Dell'Aniello S, Simon TA, Suissa S. Abatacept initiation in rheumatoid arthritis and the risk of serious infection: A population-based cohort study. Semin Arthritis Rheum. 2019 Jun;48(6):1053-1058. doi:10.1016/j.semarthrit. 2019.01.009. Epub 2019 Jan 25. PMID: 30772001. 29: Pawar A, Desai RJ, Solomon DH, Santiago Ortiz AJ, Gale S, Bao M, Sarsour K, Schneeweiss S, Kim SC. Risk of serious infections in tocilizumab versus other biologic drugs in patients with rheumatoid arthritis: a multidatabase cohort study. Ann Rheum Dis. 2019 Apr;78(4):456-464. doi:10.1136/annrheumdis-2018-214367. Epub 2019 Jan 24. PMID: 30679153. 30: Berry JG, Goodman DM, Coller RJ, Agrawal R, Kuo DZ, Cohen E, Thomson J, DeCourcey D, DeJong N, Agan A, Gaur D, Coquillette M, Crofton C, Houtrow A, Hall M. Association of Home Respiratory Equipment and Supply Use with Health Care Resource Utilization in Children. J Pediatr. 2019 Apr;207:169-175.e2. doi:10.1016/j. jpeds.2018.11.046. Epub 2019 Jan 4. PMID: 30612815.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

31: Amin A, Neuman WR, Lingohr-Smith M, Menges B, Lin J. Venous Thromboembolism Prophylaxis and Risk in the Inpatient and Outpatient Continuum of Care Among Hospitalized Acutely Ill Patients in the US: A Retrospective Analysis. Adv Ther. 2019 Jan;36(1):59-71. doi: 10.1007/s12325-018-0846-2. Epub 2018 Dec 12. PMID: 30543037. 32: Raimundo K, Solomon JJ, Olson AL, Kong AM, Cole AL, Fischer A, Swigris JJ. Rheumatoid Arthritis-Interstitial Lung Disease in the United States: Prevalence, Incidence, and Healthcare Costs and Mortality. J Rheumatol. 2019 Apr;46(4):360-369. doi: 10.3899/ jrheum.171315. Epub 2018 Nov 15. Erratum in: J Rheumatol. 2019 Feb;46(2):218. PMID: 30442831.7990903465926. PMID: 19961283.

Immunology

1: Karpes Matusevich AR, Duan Z, Zhao H, Lal LS, Chan W, Suarez-Almazor ME, Giordano SH, Swint JM, Lopez-Olivo MA. Treatment sequences after discontinuing a tumor necrosis factor inhibitor in patients with rheumatoid arthritis. A comparison of cycling versus swapping strategies. Arthritis Care Res (Hoboken). 2020 Jun 17. doi: 10.1002/acr.24358. Epub ahead of print. PMID: 32558339. 2: McGrath LJ, Spangler L, Curtis JR, Ehrenstein V, Sørensen HT, Saul B, Levintow SN, Reams D, Bradbury BD, Brookhart MA. Using negative control outcomes to assess the comparability of treatment groups among women with osteoporosis in the United States. Pharmacoepidemiol Drug Saf. 2020 Aug;29(8):854-863. doi:10.1002/pds.5037. Epub 2020 Jun 14. PMID: 32537883. 3: Curtis JR, Owensby JK, Xie F. Comparative safety of flavocoxid vs prescription NSAIDs among osteoarthritis patients. Osteoarthritis Cartilage. 2020 Jul;28(7):917-923. doi:10.1016/ j.joca.2020.03.017. Epub 2020 Apr 17. PMID: 32305527. 4: Bell CF, Priest J, Stott-Miller M, Kan H, Amelio J, Song X, Limone B, Noxon V, Costenbader KH. Real-world treatment patterns, healthcare resource utilisation and costs in patients with systemic lupus erythematosus treated with belimumab: a retrospective analysis of claims data in the USA. Lupus Sci Med. 2020 Mar 26;7(1):e000357. doi: 10.1136/lupus-2019-000357. PMID: 32341790; PMCID: PMC7174061. 5: Egiziano G, Widdifield J, Rahman A, Vinet E, Moura CS, Curtis JR, Bernatsky S. Antiphospholipid Antibody Testing in a General Population Sample from the USA: An Administrative Database Study. Sci Rep. 2020 Feb 20;10(1):3102. doi:10.1038/s41598-020-59990-5. PMID: 32080284; PMCID: PMC7033098. 6: Ross PR, Lan WC, Chen JS, Kuo CF, Chung KC. Revision surgery after vascularized or non-vascularized scaphoid nonunion repair: A national population study. Injury. 2020 Mar;51(3):656-662. doi: 10.1016/j.injury.2020.01.035. Epub 2020 Jan 28. PMID: 32033804.

7: Shaker M, Chalil JM, Tran O, Vlahiotis A, Shah H, King T, Green TD, Greenhawt M. Commercial claims costs related to health care resource use associated with a diagnosis of peanut allergy. Ann Allergy Asthma Immunol. 2020 Apr;124(4):357-365.e1. doi: 10.1016/j.anai.2020.01.004. Epub 2020 Jan 16. PMID: 31954759. 8: Lee H, Jin Y, Liu J, Cohen EM, Chen SK, Kim SC. Risk of Diabetes Mellitus in Patients with Juvenile Idiopathic Arthritis. J Rheumatol. 2019 Dec 1:jrheum.190644. doi: 10.3899/jrheum.190644. Epub ahead of print. PMID: 31787600. 9: Kang EH, Jin Y, Desai RJ, Liu J, Sparks JA, Kim SC. Risk of exacerbation of pulmonary comorbidities in patients with rheumatoid arthritis after initiation of abatacept versus TNF inhibitors: A cohort study. Semin Arthritis Rheum. 2020 Jun;50 (3):401-408. doi: 10.1016/j.semarthrit.2019.11.010. Epub 2019 Nov 15. PMID: 31813561. 10: Roland LT, Nagy C, Wang H, Moore R, Cahill KN, Laidlaw TM, Wise SK, DelGaudio JM, Kuruvilla M, Levy JM. Treatment practices for aspirin-exacerbated respiratory disease: analysis of a national insurance claims database. Int Forum Allergy Rhinol. 2020 Feb;10(2):190-193. doi: 10.1002/alr.22471. Epub 2019 Nov 6. PMID: 31693796; PMCID: PMC7060492. 11: Ghaswalla P, Poirrier JE, Packnett ER, Irwin DE, Gray SR, Buck PO. Maternal Immunization in the U.S.: A Nationwide Retrospective Cohort Study. Am J Prev Med. 2019 Sep;57(3):e87-e93. doi: 10.1016/j.amepre.2019.04.013. PMID: 31427034. 12: Roland LT, Wang H, Mehta CC, Cahill KN, Laidlaw TM, DelGaudio JM, Wise SK, Levy JM. Longitudinal progression of aspirin-exacerbated respiratory disease: analysis of a national insurance claims database. Int Forum Allergy Rhinol. 2019 Dec;9(12):1420-1423. doi: 10.1002/alr.22412. Epub 2019 Aug 23. PMID: 31442000; PMCID: PMC6901725. 13: Kang EH, Jin Y, Tong AY, Desai RJ, Kim SC. Risk of serious infection among initiators of TNF inhibitors plus methotrexate versus triple therapy for rheumatoid arthritis: a cohort study. Arthritis Care Res (Hoboken). 2019 Aug 3. doi: 10.1002/ acr.24038. Epub ahead of print. PMID: 31376333. 14: Chen C, Hartzema AG, Xiao H, Wei YJ, Chaudhry N, Ewelukwa O, Glover SC, Zimmermann EM. Real-world Pattern of Biologic Use in Patients With Inflammatory Bowel Disease: Treatment Persistence, Switching, and Importance of Concurrent Immunosuppressive Therapy. Inflamm Bowel Dis. 2019 Jul 17;25(8):1417-1427. doi:10.1093/ibd/izz001. PMID: 30839057. 15: Chen SK, Feldman CH, Brill G, Lee YC, Desai RJ, Kim SC. Use of prescription opioids among patients with rheumatic diseases compared to patients with hypertension in the USA: a retrospective cohort study. BMJ Open. 2019 Jun 19;9(6):e027495. doi: 10.1136/bmjopen-2018-027495. PMID: 31221884; PMCID: PMC6589005. 16: Lee MP, Desai RJ, Jin Y, Brill G, Ogdie A, Kim SC. Association of Ustekinumab vs TNF Inhibitor Therapy With Risk of Atrial Fibrillation and Cardiovascular Events in Patients With Psoriasis or Psoriatic Arthritis. JAMA Dermatol. 2019 Jun 1;155(6):700-707. doi: 10.1001/jamadermatol.2019.0001. PMID: 30916734; PMCID: PMC6563547.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

17: Sears ED, Lu YT, Chung TT, Momoh AO, Chung KC. Pathology Evaluation of Reduction Mammaplasty Specimens and Subsequent Diagnosis of Malignant Breast Disease: A Claims-Based Analysis. World J Surg. 2019 Jun;43(6):1546-1553. doi:10.1007/s00268-019-04931-1. PMID: 30719555; PMCID: PMC7422755. 18: Ghate S, Ionescu-Ittu R, Burne R, Ndife B, Laliberté F, Nakasato A, Duh MS. Patterns of treatment and BRAF testing with immune checkpoint inhibitors and targeted therapy in patients with metastatic melanoma presumed to be BRAF positive. Melanoma Res. 2019 Jun;29(3):301-310. doi:10.1097/ CMR.0000000000000504. PMID: 30247203; PMCID: PMC6494034. 19: Kim SC, Pawar A, Desai RJ, Solomon DH, Gale S, Bao M, Sarsour K, Schneeweiss S. Risk of malignancy associated with use of tocilizumab versus other biologics in patients with rheumatoid arthritis: A multi-database cohort study. Semin Arthritis Rheum. 2019 Oct;49(2):222-228. doi: 10.1016/j.semarthrit.2019.03.002. Epub 2019 Mar 9. PMID: 30967248. 20: Zhou F, Xu J, Black CL, Ding H, Cho BH, Lu PJ, Lindley MC. Trends in Tdap vaccination among privately insured pregnant women in the United States, 2009-2016. Vaccine. 2019 Mar 28;37(14):1972-1977. doi:10.1016/j.vaccine.2019.02.042. Epub 2019 Feb 27. PMID: 30826146; PMCID: PMC6557580. 21: Luo R, Sickler J, Vahidnia F, Lee YC, Frogner B, Thompson M. Diagnosis and Management of Group a Streptococcal Pharyngitis in the United States, 2011-2015. BMC Infect Dis. 2019 Feb 26;19(1): 193. doi: 10.1186/s12879-019-3835-4. PMID: 30808305; PMCID: PMC6390592. 22: Baker JM, Dahl RM, Cubilo J, Parashar UD, Lopman BA. Effects of the rotavirus vaccine program across age groups in the United States: analysis of national claims data, 2001-2016. BMC Infect Dis. 2019 Feb 22;19(1):186. doi:10.1186/s12879-019-3816-7. PMID: 30795739; PMCID: PMC6387516. 23: Pawar A, Desai RJ, Solomon DH, Santiago Ortiz AJ, Gale S, Bao M, Sarsour K, Schneeweiss S, Kim SC. Risk of serious infections in tocilizumab versus other biologic drugs in patients with rheumatoid arthritis: a multidatabase cohort study. Ann Rheum Dis. 2019 Apr;78(4):456-464. doi:10.1136/annrheumdis-2018-214367. Epub 2019 Jan 24. PMID: 30679153. 24: Ellis LA, Malangone-Monaco E, Varker H, Stetsovsky D, Kubacki M, DeHoratius RJ, Kafka S. Comparative analysis of US real-world dosing patterns and direct infusion-related costs for matched cohorts of rheumatoid arthritis patients treated with infliximab or intravenous golimumab. Clinicoecon Outcomes Res. 2019 Jan 15;11:99-110. doi: 10.2147/CEOR.S185547. PMID: 30679916; PMCID: PMC6338107. 25: Sloan VS, Sheahan A, Stark JL, Suruki RY. Opioid Use in Patients with Ankylosing Spondylitis Is Common in the United States: Outcomes of a Retrospective Cohort Study. J Rheumatol. 2019 Nov;46(11):1450-1457. doi:10.3899/jrheum.180972. Epub 2019 Jan 15. PMID: 30647189.

26: Huetteman HE, Shauver MJ, Malay S, Chung TT, Chung KC. Variation in the Treatment of Distal Radius Fractures in the United States: 2010 to 2015. Plast Reconstr Surg. 2019 Jan;143(1):159-167. doi: 10.1097/PRS.0000000000005088. PMID: 30589789; PMCID: PMC6311711.

Neurology 1: Coleman CI, Baker WL, Meinecke AK, Eriksson D, Martinez BK, Bunz TJ, Alberts MJ. Effectiveness and safety of rivaroxaban vs. warfarin in patients with non-valvular atrial fibrillation and coronary or peripheral artery disease. Eur Heart J Cardiovasc Pharmacother. 2020 Jul 1;6(3):159-166. doi:10.1093/ehjcvp/pvz047. PMID: 31549153. 2: Medress Z, Ugiliweneza B, Parker J, Wang D, Burton E, Boakye M, Skirboll S. Simulating Episode-Based Bundled Payments for Cranial Neurosurgical Procedures. Neurosurgery. 2020 Jul 1;87(1):86-95. doi: 10.1093/neuros/nyz353. PMID: 31515558. 3: Yong CM, Tremmel JA, Lansberg MG, Fan J, Askari M, Turakhia MP. Sex Differences in Oral Anticoagulation and Outcomes of Stroke and Intracranial Bleeding in Newly Diagnosed Atrial Fibrillation. J Am Heart Assoc. 2020 May 18;9(10):e015689. doi: 10.1161/JAHA.120.015689. Epub 2020 May 12. PMID: 32394763. 4: Brown TM, Bittner V, Colantonio LD, Deng L, Farkouh ME, Limdi N, Monda KL, Rosenson RS, Serban MC, Somaratne RM, Zhao H, Woodward M, Muntner P. Residual risk for coronary heart disease events and mortality despite intensive medical management after myocardial infarction. J Clin Lipidol. 2020 Mar-Apr;14(2):260-270. doi: 10.1016/j.jacl.2020.01.004. Epub 2020 Jan 23. PMID: 32115398. 5: Fulton BD, Proudman DG, Sample HA, Gelfand JM, Chiu CY, DeRisi JL, Wilson MR. Exploratory analysis of the potential for advanced diagnostic testing to reduce healthcare expenditures of patients hospitalized with meningitis or encephalitis. PLoS One. 2020 Jan 15;15(1):e0226895. doi:10.1371/journal.pone. 0226895. PMID: 31940319; PMCID: PMC6961903. 6: Mintzer S, Yi M, Hegarty S, Maio V, Keith S. Hyperlipidemia in patients newly treated with anticonvulsants: A population study. Epilepsia. 2020 Feb;61(2):259-266. doi: 10.1111/epi.16420. Epub 2020 Jan 7. PMID: 31912492. 7: Youngerman BE, Joiner EF, Wang X, Yang J, Welch MR, McKhann GM 2nd, Wright JD, Hershman DL, Neugut AI, Bruce JN. Patterns of seizure prophylaxis after oncologic neurosurgery. J Neurooncol. 2020 Jan;146(1):171-180. doi:10.1007/s11060-019-03362-1. Epub 2019 Dec 13. PMID: 31834582. 8: Miao B, Alberts MJ, Bunz TJ, Coleman CI. Safety and effectiveness of oral factor Xa inhibitors versus warfarin in nonvalvular atrial fibrillation patients at high-risk for falls. J Thromb Thrombolysis. 2019 Oct;48(3):366-372. doi:10.1007/s11239-019-01898-7. PMID: 31228038.

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IBM Watson Health IBM MarketScan Bibliography by Therapeutic Area

9: Thurman DJ, Faught E, Helmers S, Kim H, Kalilani L. New-onset lesional and nonlesional epilepsy in the US population: Patient characteristics and patterns of antiepileptic drug use. Epilepsy Res. 2019 Nov;157:106210. doi:10.1016/j.eplepsyres.2019.106210. Epub 2019 Sep 25. PMID: 31605878. 10: Zhuang S, Na M, Winkelman JW, Ba D, Liu CF, Liu G, Gao X. Association of Restless Legs Syndrome With Risk of Suicide and Self-harm. JAMA Netw Open. 2019 Aug 2;2(8):e199966. doi:10.1001/ jamanetworkopen.2019.9966. PMID: 31441941; PMCID: PMC6714009. 11: van der Goes DN, Ney JP, Garrison LP. Determinants of specialist physician ambulatory visits: a neurology example. J Med Econ. 2019 Aug;22(8):830-839. doi:10.1080/13696998.2019 . 1618861. Epub 2019 Jun 18. PMID: 31081729. 12: Guptill JT, Runken MC, Eaddy M, Lunacsek OE, Fuldeore RM, Blanchette CM, Zacherle E, Noone JM. Two comparative assessments of intravenous immunoglobulin therapy switching patterns in the treatment of chronic inflammatory demyelinating polyneuropathy in the US. Patient Prefer Adherence. 2019 Apr 30;13:649-655. doi: 10.2147/PPA.S185852. PMID: 31118588; PMCID: PMC6503323. 13: Kalilani L, Faught E, Kim H, Burudpakdee C, Seetasith A, Laranjo S, Friesen D, Haeffs K, Kiri V, Thurman DJ. Assessment and effect of a gap between new-onset epilepsy diagnosis and treatment in the US. Neurology. 2019 May 7;92(19):e2197-e2208. doi:10.1212/WNL. 0000000000007448. Epub 2019 Apr 10. PMID: 30971487; PMCID: PMC6537131.

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14: Montastruc F, Renoux C, Dell'Aniello S, Simon TA, Azoulay L, Hudson M, Suissa S. Abatacept initiation in rheumatoid arthritis and the risk of cancer: a population-based comparative cohort study. Rheumatology (Oxford). 2019 Apr 1;58(4):683-691. doi:10.1093/ rheumatology/key352. PMID: 30535094; PMCID: PMC6434371. 15: Adil SM, Liu B, Charalambous LT, Kiyani M, Gramer R, Swisher CB, Verbick LZ, McCabe A, Parente BA, Pagadala P, Lad SP. Healthcare Economics of Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage in the United States. Transl Stroke Res. 2019 Dec;10 (6):650-663. doi: 10.1007/s12975-019-00697-9. Epub 2019 Mar 13. PMID: 30864050. 16: Kim Y, Krause TM, Blum P, Freeman L. Disease modifying therapies continue to drive up health care cost among individuals with multiple sclerosis. Mult Scler Relat Disord. 2019 May;30:69-75. doi: 10.1016/j.msard.2019.02.006. Epub 2019 Feb 5. PMID: 30738875. 17: Montastruc F, Renoux C, Hudson M, Dell'Aniello S, Simon TA, Suissa S. Abatacept initiation in rheumatoid arthritis and the risk of serious infection: A population-based cohort study. Semin Arthritis Rheum. 2019 Jun;48(6):1053-1058. doi: 10.1016/j.semarthrit. 2019.01.009. Epub 2019 Jan 25. PMID: 30772001. 18: Song X, Said Q, Tran O, Krueger DA, Bissler J. Everolimus compliance and persistence among tuberous sclerosis complex patients with renal angiomyolipoma or subependymal giant cell astrocytoma. Curr Med Res Opin. 2019 Jun;35(6):1103-1110. doi: 10.1080/03007995.2018.1558883. Epub 2019 Jan 14. PMID: 30550347.