caregiver alternatives to running on empty · 2019-03-16 · “super-agers” suggest modifiable...
TRANSCRIPT
LISA P. GWYTHER MSW, LCSW
D U K E F A M I L Y S U P P O R T P R O G R A M
D U K E C E N T E R F O R A G I N G
D U K E O L L I
S T . L U K E ’ S E P I S C O P A L C H U R C H
D U R H A M , N C
M A R C H 2 1 2 0 1 8
Cognitive Aging:Evidence for Action
Federal Trade Commission 2016
Duke Family Support Program, March 2018
Lumosity paid $2M to
settle FTC deceptive
advertising charges for
“Brain Training” program
Claimed program would
sharpen performance in
everyday life and protect
against cognitive decline
Institute of Medicine (2015)
Duke Family Support Program, March 2018
Cognitive Aging: Progress in Understanding and Opportunities for Action
Sponsors
McKnight Brain Research Foundation
National Institute on Aging
National Institute of Neurological Disorders and Stroke
Centers for Disease Control and Prevention
Retirement Research Foundation
AARP
What is Cognitive Aging?
Duke Family Support Program, March 2018
Cognition includes attention, thinking, understanding, learning, remembering, solving problems, reasoning and making decisions.
Cognitive aging is a process of gradual, ongoing, yet highly variable changes in cognitive functions as people age.
With aging, cognitive health means maintenance of optimal cognitive function over time.
Myths about Cognitive Aging
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It’s too late to benefit from lifestyle changes
All memory loss is Alzheimer’s
All memory loss is normal with age
It’s all in the genes and because I couldn’t pick my parents, I’m going to get Alzheimer’s
Vitamins, supplements and memory boosters prevent cognitive aging
Key Features of Cognitive Aging
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• Inherent in humans and animals as they age
• Occurs across the spectrum of individuals as they age regardless of initial cognitive function
• Highly dynamic process with variability within and between individuals
• Includes cognitive domains that may not change, may decline, or may actually improve with aging, and there is the potential for older adults to strengthen some cognitive abilities
• Only now beginning to be understood biologically yet clearly involves structural and functional brain changes
• Not a clinically-defined neurological or psychiatric disease such as Alzheimer’s disease and does not inevitably lead to neuronal death and neurodegenerative dementia.
People Forget
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Misplace keys, glasses
Why did I come in here?
Forget names, but may remember later
Notice search for words
Calendars, notes, reminders, smart phones and clocks help
Senior Moments but usually remember you forgot
Expectable Aging Changes
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Mild declines in:
Visual and verbal memory
Visuospatial abilities
Immediate memory
Ability to name objects
Ability to maintain attention
Common to have less recall of recent events and be slower to remember names and details
Vocabulary remains unchanged or may improve
Financial Decision-Making Risks with Expectable Aging Changes
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Over 2.9 billion lost to elder financial abuse
Includes loss of money and goods to legitimate businesses, financial advisors, scams, family, and friends and fraud
Learn more at consumerfinance.gov
Protect Your Cognitive Health (2015)
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The Good News
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A third of Alzheimer's disease cases worldwide
might be attributable to potentially modifiable
risk factors. Alzheimer's disease incidence might
be reduced through improved access to
education and use of effective methods targeted
at reducing the prevalence of vascular risk
factors, poor quality sleep and depression.
−K. Yaffe, 2014 & 2016
“Super-Agers” Suggest Modifiable Protective Factors
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“Super-agers” 2016 findings: People with extensive brain plaques and tangles which should result in neuron death retain superior memory. What protects neurons against the pathology and loss of function?
Stimulating lifestyles? Complex work environments? Genetics? Dietary patterns? Environmental – protective medications,
early or mid-life environments?
2017 Report
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Preventing Cognitive Decline and Dementia: A Way Forward, 2017
“…encouraging although inconclusive” evidence for three specific types of interventions
o cognitive training
o blood pressure control for people with hypertension
o Increased physical activity
Interventions that May Help Prevent Cognitive Decline and Dementia
The ACTIVE Study: Ten Year Follow Up
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11-14 hours of speed training (virtually processing information quickly) beat memory and reasoning training after 10 years of follow-up with healthy older adults. (2017)
Posit Science 2016 program: Brain HQ “Double Decision” updated speed training preview
8 Later-Life Modifiable Lifestyle Changes To Reduce Cognitive Decline (Lancet 2017)
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Protect hearing – decrease social isolation and depression
Control depression
Stay active and fit with aerobic and progressive strength training for
mood, balance, preserved white matter associated with better problem
solving and decisions (2018)
Lower high blood pressure – stop smoking
Stay socially engaged – loneliness is a risk for high blood pressure,
heart disease and depression
Treat diabetes
Lose excess weight – Mediterraean diet
Restorative sleep
Lifestyle Counseling Prevents Decline (2018)
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FINGER trial: 1109 Fins including 1/3 ApoE4 carriers (genetically at risk) aged 60-77 yrs. old followed 2+ years
Nutrition, exercise, cardiovascular disease management and counseling significantly prevented cognitive decline.
Global trials underway with diverse groups
Physical Fitness: 90% Reduced Dementia Risk
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March 2018 Neurologyresearch article followed Swedish women 44 yrs –those with high fitness levels had an 88% reduction in dementia risk and later onset in later life.
2014 meta analysis of 21 studies: physically active adults were at 35% lower risk of cognitive decline
Physical Activity & Exercise: Interventional Data
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Meta-analyses (2017) found modest effect sizes that were moderated by: Cognitive processes being assessed: larger
benefits for executive control processes
Gender: women more than men,
Exercise type: combined aerobic and progressive strength training better than aerobic alone
Age: > 65 years showed larger benefits
Duration: exercise sessions longer than 30 minutes showed larger benefit
“Sitting is the new smoking”
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Stairs
Sweep
Push a grandchild on a swing
Throw a ball for the dog
Dance in your living room
Think Movement, Not Just Exercise
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Aerobic exercise like walking, swimming
Progressive resistance or strength training bands and weights 2 times/week (CDC 2017)
Yoga and tai chi – balance, strength and flexibility
Find Meaning in Movement
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Exercise improves mood, buffers depression, preserves white matter executive function (2018)
Exercise reduces risk of fall injury
Exercise with others adds benefits of social stimulation
Give Your Brain A Boost
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Eat a rainbow – food, not supplements – Mediterranean Diet showed less brain shrinkage over 3 years in 1000 70+ (2017)
Play a game, practice a craft
Surf the web
Socialize with friends
Play an instrument
Rest
The more the merrier (combine the above)
MIND DIET
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Butter and margarine
Cheese
Red meat
Fried food
Pastries and sweets
Green, leafy vegetables
All other vegetables
Berries
Nuts
Olive oil
Whole grains
Fish
Beans
Poultry
Wine
Eat these
10
Limit these
5
Vitamins: Interventional Data
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Folate supplementation has NOT produced improved cognitive benefit among people, in general, although some benefit has been shown among those with high homocysteine levels
B12 supplementation does NOT appreciably change cognitive function or decline
Check out Supplements
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Natural doesn’t mean safe
Supplements can make your prescription meds weaker or stronger
Supplements may adversely affect certain medical conditions
Avoid ingredients you don’t need and don’t assume more is better
Check the science from a reliable source (NCCIH)
Medications and Cognitive Decline
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Older adults are prescribed 14 drugs per year on average
Avoid high risk meds, such as those on the AGS Beers list – pain and anxiety meds, PM meds for sleep
20 – 50% of older adults are on anticholinergic drugs (associated with cognitive impairment)
Avoid potent over-the-counter antihistamines such as Benadryl
Restorative Sleep: A Brain Booster
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Warm bath or pre-sleep ritual
Room temperature adjustment, darkness, white noise
No caffeine, chocolate, alcohol after noon
Hospitalization and Cognitive Aging
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In process of aging, older adults are exposed to many factors which may accelerate cognitive decline:
Nearly every older adult will experience at least one acute illness, surgery, or hospitalization
Nearly 1/3 will be hospitalized each year
−HHS, Profile of Older Americans, 2013
Prevention of Delirium
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Delirium is the most common
complication of hospitalization in
older persons, 2.6 million older
adults/year
Leading contributor to cognitive
decline following hospitalization,
major illness, and surgery
At least 40% of cases are
preventable through targeted risk
factor approaches, like HELP or
Duke’s POSH.
Sensory Loss and Cognitive Health
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Uncorrected deficits in hearing and vision may impact cognition and dementia risk
What studies have shown:
An association between vision impairment and compromised brain function
Stronger evidence that hearing loss can speed cognitive decline
What Else Contributes to Cognitive Decline?
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Negative expectations • Lack of organization Grief • Worry • Fatigue • Pain
“Eat, Pray, Love” and More
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Volunteer – meaningful engagement enhances cognition –Experience Corps long term benefits (2017)
Sing in a choir
Shop
Strategy games
Mindfulness-based meditation
Seek novelty, creative outlets, pay attention and challenge yourself
OLLI, MOOCs, COURSERA & BEYOND
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Risk Factors Awaiting More Research
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Stress
Social isolation/ loneliness
Early life factors, especially poverty, education quality, literacy, trauma
Chronic inflammation in mid life associated with brain shrinkage and AD (2017)
Cholesterol levels
What Else Helps?
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Typical Forgetting: What Helps?
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Write it down
Check reminder cues –smart phones
Give everything a place, especially by door
Limit multi-tasking, clutter
Say it out loud to focus attention
Story methods to connect items
Chunk numbers or categorize
Forgetting: What You Can Do?
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Limit processed foods
Helmets and seat belts
Falls prevention
Manage stress
Mindfulness, meditation, yoga
Pace and set priorities
Prevention of Alzheimer’s
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Dementia may be a disorder that develops over a lifetime, with individual ways to build a better brain as we age.
−Galvin JE, JAGS, Oct. 2017
Remember This
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It’s never too early or too late –brains can change with experience
Mood and mobility matter
Treat CVD-risk illnesses
Walk more, more often and with friends – set and pursue goals and purpose, keep records and reward yourself
Forgetting: When to Get Help
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Getting lost in familiar places
Repetitive questioning, checking, worry
Money, medication and moving violation mistakes
Odd or uncharacteristic behavior, mood, personality changes
Falls or change in balance, unexplained injuries
Better Outcomes with Early Diagnosis
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Access available treatments
Access support services
Better manage medications
Receive counseling
Address driving and safety issues
Manage co-occurring conditions
Advance planning
−CDC 2017
Take Action: Participate in Research
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Are you over 65 years old?
Have you stood by a friend or family member living with Alzheimer’s or a related disorder (ADRD)?
Are you concerned about ADRD in your future?
Do you want to know about options to participate in Alzheimer’s prevention studies?
Are you currently free from a diagnosis of Alzheimer’s?
JOIN DUKE’S AD PREVENTION REGISTRY
DUKE FAMILY SUPPORT PROGRAM
DUKEFAMILYSUPPORT.ORG
919-660-7510
Questions???