Borami SeoPolicy Manager

동물보호시민단체 카라 KARA

KOREA’S FAST MOVING INTER-EST IN NON-ANIMAL TESTING AND EFFORT TO END COSMET-ICS TESTING USING ANIMALS

Contents

Animal Testing – Regulations

Replacement of animal testing

Replacement of animal testing – Cosmetics & Non-Cosmetics

Effort to end cosmetics testing using animals

Animal Testing – Regulations

Ministry of Agriculture, Food and Rural Affairs 1991 Animal Protection Act 2006 – APA: Animals used in Experiments 2013 – revision of the Act, attempt to ban cosmetics animal testing

Promotion of Alternatives to Animal Testing Act ??

Ministry of Health and Wel-fare

2005 Bioethics & Biosafety Act

Ministry of Food and Drug Safety 2000 Cosmetics Act 2008 Lab Animal Act

Replacement of Animal Testing

1985 Korean Association for Laboratory Animal Science 1997 Project on In vitro develop-ment for the safety evaluation of skin product  

Replacement of Animal Testing

1985 Korean Association for Laboratory Animal Science 1997 Project on In vitro develop-ment for the safety evaluation of skin product  

2006 Research Society for Alternatives to Animal Experiments → National Society

2008 Laboratory Animal Act estab-lished

2009 KoCVAM established

EU Announcement WC7 Japan

Replacement of Animal Testing

1985 Korean Association for Laboratory Animal Science 1997 Project on In vitro develop-ment for the safety evaluation of skin product  

2006 Research Society for Alternatives to Animal Experiments → National Soci-ety

2008 Laboratory Animal Act estab-lished

2009 KoCVAM established 2011 Joined ICATM

2013 The Centre of Alternative Methods for Safety Evaluation of Cosmetics – CAMSEC

2013 MFDS investment in establishing the nation’s first cetre for the develop-ment and validation of alternatives to animal testing 2014 Symposium on in silico by Korea In-stitute of Technology

EU Announcement WC7 Japan

2013 Avison Biomedical Research CentreBiggest animal testing facility in Asia

Replacement of Animal Testing

Replacement for Cosmetics The Centre of Alternative Methods for Safety Evaluation of Cos-meticsLed by Science Advisor of KoCVAM, Prof. Youngjin Chun Only cosmetics company investing on replacement – Amore Pa-

cific Limitation of the role of KoCVAM

Replacement for Non-Cosmetics KIST(Korea Institute of Science and Technology)2013 3 year-project: Multi-organ toxicity assessment using molecular screening and omix-technology Currently preparing a project proposal to Ministry of Sciences, ICT & Future Planning KIT Korea Institute of Toxicology 2014 Symposium: In silico models for predictive toxicology

Effort to end cosmetics animal testing

Revision of Animal Protection Act in 2013- Animal Experiments part with Congresswoman Junglim Moon

2012 Labelling bill proposed by Congresswoman Moon Proposed draft for APA- to end cosmetics animal testing for both ingredients and finished products - to encourage government’s support for alternatives ‘Industries are expecting the ban’ but WHEN???

Effort to end cosmetics animal testing

Public Awareness CampaignWorking with cosmetics brands & public engagementList of companies confirming non-animal testing policy

Development of alternative test methods in Korea

Alternative test methods for reproductive and developmental toxicology In vitro model of granuloma-like cell aggregates associated with early host immune re-sponses against Mycobacterium massiliense infection Alternative method for efficacy tests using in vivo imaging tools; reduction and refinement of 3R in animal use

International development of alternative test methods

Current trends of research and development of alternative methods through WC9 review Cases of OECD guideline development by JaCVAM Toxicogenomics as alternative of traditional toxicological endpoints

Development of alternative skin test methods

In vitro percutaneous absorption of benzophenone-3, a UV filter 3D cell culture models to study cancer Strategy of immortalization using viral vectors to extend life-span in primary cultured cells Keratinocyte-derived IL-24 as a positive feedback regulator of epidermal inflammation and its implication in in vitro skin safety testing methods

Is One R the new Three Rs?

Thank you!

Photo: Christina Dodkin