axial length and lens thickness - movu · adi abulafia, md, warren e. hill, md, douglas d. koch,...

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LT AL Axial length and Lens Thickness →The longer the eye, the smaller the ratio of lens to AL, i.e. Distance from posterior lens to retina more dominant for longer AL -> Reduced composite refractive index for whole eye. →Conventional optical biometer uses composite refractive index weighing this ratio of Lens to AL which is AL dependent However, longer eye outside of normal eye population are disregarded significantly when extrapolating with linear fit because of small population of longer eye and some people actually have large ratio LT not obeying the linear trend 0.00 1.00 2.00 3.00 4.00 5.00 6.00 7.00 10% 15% 20% 25% 30% 35% 40% 20.00 22.00 24.00 26.00 28.00 LT [mm] LT/AL ratio Axial Length [mm] AL and LT correlation Ratio LT Linear (Ratio) y = -0.0011x + 1.3761 1.346 1.347 1.348 1.349 1.35 1.351 1.352 1.353 1.354 1.355 20.00 21.00 22.00 23.00 24.00 25.00 26.00 Composite Refractive index AL [mm]

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  • LT

    AL

    Axial length and Lens Thickness

    →The longer the eye, the smaller the ratio of lens to AL, i.e.

    Distance from posterior lens to retina more dominant for longer AL

    -> Reduced composite refractive index for whole eye.

    →Conventional optical biometer uses

    composite refractive index weighing this ratio of

    Lens to AL which is AL dependent

    However, longer eye outside of

    normal eye population are

    disregarded significantly when

    extrapolating with linear fit because

    of small population of longer eye

    and some people actually have large

    ratio LT not obeying the linear trend

    0.00

    1.00

    2.00

    3.00

    4.00

    5.00

    6.00

    7.00

    10%

    15%

    20%

    25%

    30%

    35%

    40%

    20.00 22.00 24.00 26.00 28.00

    LT [

    mm

    ]

    LT/A

    L ra

    tio

    Axial Length [mm]

    AL and LT correlation

    Ratio LT Linear (Ratio)

    y = -0.0011x + 1.3761

    1.346

    1.347

    1.348

    1.349

    1.35

    1.351

    1.352

    1.353

    1.354

    1.355

    20.00 21.00 22.00 23.00 24.00 25.00 26.00

    Composite Refractive index

    AL [mm]

  • • Conventional Optical Biometer:Optical length from cornea to retina / composite refractive index (e.x. na=1.3761-0.0011xAL)

    • ARGOS:Sum of all segments(CCT/1.375+AD/1.336+LT/1.41+PosLens-Retina/1.336 )

    Error of +/-0.05mm(1.96SD) is added to

    AL for IOL calculation.

    Difference of how AL is calculated

    Especially for longer eye(>26mm), conventional biometer

    deviates with the overestimation of AL because of dividing by too

    small refractive index even for the eye with large LT which is not

    true to the physical size.

    LT

    ALo

    pt/n

    a

    AD

    CC

    T Difference between two methods

    -0.20

    -0.15

    -0.10

    -0.05

    0.00

    0.05

    0.10

    0.15

    0.20

    20.00 21.00 22.00 23.00 24.00 25.00 26.00 27.00 28.00

    [mm]

    AL [mm]

  • 63%

    85%

    94%

    53%

    80%

    96%

    0%

    10%

    20%

    30%

    40%

    50%

    60%

    70%

    80%

    90%

    100%

  • Accurate prediction without AL adjustment

    Barrett Universal II

    *Hill-RBF based on the curated data with Alcon SN60WF only

    and generally works only with bioconvex lens(+6-+30D) type

    i.e. it is not as accurate if the other model is used.

  • Accuracy of predicted refraction with multifocal intraocular lenses using two biometry measurement

    devices and multiple intraocular lens power calculation formulas

    Article · Dec 2014 · Clinical and Experimental Ophthalmology

    Reitblat O1,2, Assia EI1,3,4, Kleinmann G1,2,5, Levy A1, Barrett GD6, Abulafia A1

    Barrett Universal II

    Considering Lens Factor for better lens position estimation

    N=73 eyes

  • Comparison of Methods to Predict Residual Astigmatism After Intraocular Lens Implantation

    Adi Abulafia, MD; Warren E. Hill, MD; Maria Franchina, MD; Graham D. Barrett, MD

    Journal of Refractive Surgery

    October 2015 - Volume 31 · Issue 10: 699-707

    Barrett Toric Calculator

    • Considering Posterior curvature of cornea

    • Better prediction including Against-the-rule astigmatism

    • Alcon online calculator now uses Barrett Toric

  • Prediction of refractive outcomes with toric intraocular lens implantation

    Adi Abulafia, MD, Graham D. Barrett, MD, et al., J Cataract Refract Surg 2015; 41:936–944

    Barrett Toric Calculator

    No need for Baylor monogram shift for WTR, ATR astigmatism

  • Barrett True-K

    0

    20

    40

    60

    80

    100

    60.3

    43.1

    55.248.3

    67.2

    84.581 82.8 81

    94.8

    Within ±0.5D Within±1.0D

    0

    20

    40

    60

    80

    100

    ShammasPL Haigis-L Barrett True-K

    5045.7

    63.3

    8076.7

    80

    Within ±0.5D Within±1.0D

    With History of Pre-/Post-Lasik refraction

    n=58 n=30

    No history

    % %

    Accuracy of the Barrett True-K formula

    for intraocular lens power prediction after

    laser in situ keratomileusis or photorefractive

    keratectomy for myopia

    Adi Abulafia, MD, Warren E. Hill, MD, Douglas D.

    Koch, MD, Li Wang, MD, PhD,

    Graham D. Barrett, MD

    • Based on accurate Barrett Universal II with internally

    modified K value with/without refractive surgery history

  • Barrett True-K

    n=58

    n=30

    Accuracy of the Barrett True-K formula

    for intraocular lens power prediction after

    laser in situ keratomileusis or photorefractive

    keratectomy for myopia

    Adi Abulafia, MD, Warren E. Hill, MD, Douglas D.

    Koch, MD, Li Wang, MD, PhD,

    Graham D. Barrett, MD

    With History of Pre-/Post-Lasik refraction

    No history