vol. 265, no. 33 the journal of november 25, 1990 ... · iv 20394 preferential inhibition of the...
TRANSCRIPT
Vol. 265, No. 33 The Journal of November 25, 1990
Biological Chemistry Copyright 0 1990 by the American Society for Biochemistry and Molecular Biology, Inc.
428 East Preston St.. Baltimore, MD 21202 U.S.A.
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CONTENTS*
MINIREVIEW
Ribonuclease P. Postscript. Sidney Altman
COMMUNICATIONS
Saccharomyces cerevisiae STEl4 gene is required for COOH-terminal methylation of a-factor mating pheromone.
Rachel Sterne Marr, Lindley C. Blair, and Jeremy Thorner
Molecular cloning of the fMet-Leu-Phe receptor from neutrophils.
Kathleen M. Thomas, Hue Yung Pyun, and Javier Navarro
Mapping of a retinoic acid-responsive element in the promoter region of the complement factor H gene.
Pura Munoz-Canoves, Dennis P. Vik, and Brian F. Tack
Minimum substrate sequence for signal peptidase I of Escherichia coli.
Inderjit K. Dev, Paul H. Ray, and Paul Novak
Tyrosine 385 of prostaglandin endoperoxide syn- thase is required for cyclooxygenase catalysis.
Teruhiko Shimokawa, Richard J. Kulmacz, David L. Dewitt, and William L. Smith
Immunochemical analysis of the exposure of high mobility group protein 14 and 17 surfaces in chro- matin.
Michael Bustin, Massimo P. Crippa, and James M. Pash
Transcriptional activation of G.a expression by re- tinoic acid and parathyroid hormone-related pro- tein in F9 teratocarcinoma cells.
Samuel D. H. Ghan, Gordon J. Strewler, and Robert A. Nissenson
Tyrosine radicals in Photosystem II and related model compounds. Characterization by isotopic labeling and EPR spectroscopy.
Bridgette A. Barry, Mohamed R El-Deeb, Peter 0. San- dusky, and Gerald T. Babcock
20144
Claude G. Lerner, Tatsuhiko Kobayashi, and Masayori Inouye
Isolation of subtilisin pro-sequence mutations that affect formation of active protease by localized ran- dom polymerase chain reaction mutagenesis.
Joseph E. Stukey, Virginia M. McDonough, and Charles E. Martin
The OLEI gene of Saccharomyces cerevisiae en- codes the A9 fatty acid desaturase and can be func- tionally replaced by the rat stearoyl-CoA desaturase gene.
Molecular cloning by hybrid arrest of translation in Xenopus laevis oocytes. Identification of a cDNA encoding the type I iodothyronine 5’-deiodinase from rat liver.
Donald L. St. Germain, Walburga Dittrich, Christine M. Morganelli, and Vincent Cryns
20150 Sequential degradation of chondroitin sulfate in molluscs. Desulfation of chondroitin sulfate without prior depolymerization by a novel sulfatase from Anomalocardia brasiliana.
J. Felipe de Sousa, Jr., Helena B. Nader, and Carl P. Dietrich
HIV-l tat gene induces tumor necrosis factor-b (lymphotoxin) in a human B-lymphoblastoid cell line.
20156
K. Jagannadha Sostry, Raghava H. R. Reddy, Raj Pan- dita, Klara Totpal, and Bharat B. Aggarwal
Further localization of binding sites for thrombin and protein C in human thrombomodulin.
Tatsuya Hayashi, Michitaka Zushi, Shuji Yamamoto, and Koji Suzuki
a-Dendrotoxin acceptor from bovine brain is a K+ channel protein. Evidence from the N-terminal se- quence of its larger subunit.
20160 Increased levels of junB and c-jun mRNAs in male germ cells following testicular cell dissociation. Maximal stimulation in prepuberal animals.
Victoria E. S. Scott, David N. Parcej, Jeffrey N. Keen, Acacia A. Alciuar, Laura E. Hake, Matthew P. Hardy, John B. C. Findlay, and J. Oliuer Dolly and Norman B. Hecht
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20106
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ARTICLES
Sorting of peroxisomal membrane protein PMP47 from Candida boidinii into peroxisomal membranes of Saccharomyces cerevisiae.
Mark T. McCammon, Carl A. Dowds, Kim Orth, Carolyn R. Moomaw, Clive A. Slaughter, and Joel M. Goodman
Insulin regulation of hexose transport in mouse 3T3-Ll cells expressing the human HepGZ glucose transporter.
Scott A. Harrison, Joanne M. Buxton, Brian M. Clancy, and Michael P. Czech
Sequence specificity of mRNA A@-adenosine meth- yltransferase.
Tunde Csepany, Alison Lin, Car/ J. Baldick, Jr., and Karen Beemon
Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90.
Edwin R. Sanchez, Margaret Hirst, Lawrence C. Scher- rer, Hsin-Yi Tang, Michael J. Welsh, Jeffrey M. Harmon, S. Stoney Simons, Jr., Gordon M. Ringold, and William B. Pratt
Purification and partial amino acid sequence analy- sis of two distinct tumor necrosis factor receptors from HL60 cells.
Hansruedi Loetscher, Ernst J. Schlaeger, Hans- Werner Lahm, Yu-Ching E. Pan, Werner Lesslauer, and Manfred Brockhaus
* The CONTENTS arranged by Subject Categories will be found immediately fcJllowing these CONTENTS. Full Instructions to Authors will be found in (1990) J. Biol. Chem. 265,595-605, and reprints may be obtained from the editorial office.
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20277 Structural and functional analysis of the human thymidylate synthase gene.
Sumiko Kaneda, Josephine Nalbantoglu, Keiichi Take- ishi, Kimiko Shim&, Osamu Gotoh, Takeshi Seno, and Dal Ayusawa
20285 Cellular factors involved in transcription and Tax- mediated trans-activation directed by the TGACGT motifs in human T-cell leukemia virus type I pro- moter.
Yi-Ling Xu, Neeraj Adya, Eric Siores, Qingsheng Gao, and Chou-Zen Giam
20293 Structure-function studies of the SERPIN plasmin- ogen activator inhibitor type 1. Analysis of chimeric strained loop mutants.
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20179
20188
20195
20202
20210
20220
20228
20234
20241
20247
20252
20263
20271
“Suicide” inactivation of thromboxane Az synthase. Characteristics of mechanism-based inactivation with isolated enzyme and intact platelets.
David A. Jones and F. A. Fitzpatrick
Mechanisms of inhibition of herpes simplex virus type 2 growth by 28-mer phosphorothioate oligo- deoxycytidine.
Wen-Yi Gao, Jerzy W. Jaroszewski, Jack S. Cohen, and Yung-Chi Cheng
Impaired secretion and fluid-phase endocytosis in the End4 mutant of Chinese hamster ovary cells.
Ru-Hung Wang, Penelope A. Colbaugh, Chia-Yi Kao, Elizabeth A. Rutledge, and Rockford K. Draper
Protein factors that bind to the murine 2’,5’-oli- goadenylate synthetase ME-12 gene 5’ upstream regulatory region.
Cong Yan and Igor Tamm
The carbohydrate structures of a mouse monoclonal IaG antibodv OKT3.
-Hubert Krotkiewski, Gunnar Gronberg, Bozena Krot- kiewska, Bo Nilsson, and Sigfrid Svensson
Channel formation properties of synthetic pardaxin and analogues.
Yechiel Shai, Diana Bach, and Aliza Yanovsky
Import of apocytochrome c into the mitochondrial intermembrane space along a cytochrome c, sorting pathway.
Rosemary A. Stuart, Donald W. Nicholson, Ulla Wien- hues, and Walter Neupert
Activation of membrane guanylate cyclase by an invertebrate peptide hormone.
Michael F. Coy
Amino acid substitutions Phe“’ + Leu and Ser”’ - Pro abolish cortisol and aldosterone synthesis by bovine cytochrome P45011@.
Porunelloor A. Mathew, J. Zan Mason, John M. Trant, Donita Sanders, and Michael R. Waterman
The effect of phosphate and calcium on force gen- eration in glycerinated rabbit skeletal muscle fi- bers. A steady-state and transient kinetic study.
Neil C. Millar and Earl Homsher
Molecular basis of interferon-y and lipopolysaccha- ride enhancement of phagocyte respiratory burst capability. Studies on the gene expression of several NADPH oxidase components.
Marco A. Cassatella, Flavia Bazzoni, Rebecca M. Flynn, Stefano Dusi, Giorgio Trinchieri, and Filippo Rossi
Mouse fl thalassemia, a model for the membrane defects of erythrocytes in the human disease.
Philippe Rouver-Fessard, Karen Lerov- Viard. Chantal Domenget, Amel Mrad, and Yves Beuzard
Biochemical study of a recombinant soluble inter- leukin-2 receptor. Evidence for a homodimeric structure.
Yannick Jacques, Brigitte Le Mauff, Anne Godard, Jeanne Naulet, Michael Concino. Henrv Marsh. Stephen Ip, and Jean-Paul Soulillou ” I
Purification and structure of exendin-3, a new pan- creatic secretagogue isolated from Heloderma hor- ridum venom.
John Eng, P. C. Andrews, Wayne A. Kleinman, Latika Singh, and Jean-Pierre Raufman
Stereoselectivity of lipases. I. Hydrolysis of enan- tiomeric glyceride analogues by gastric and pan- creatic lipases, a kinetic study using the monomo- lecular film technique.
Stephane Ransac, Ewa Rogalska, Youssef Gargouri, Annemieke M. T. J. Deveer, Fritz Paltauf, Gerard H. de Haas, and Robert Verger
Stereoselectivity of lipases. II. Stereoselective hy- drolysis of triglycerides by gastric and pancreatic lipases.
Ewa Rogalska, Stephane Ransac, and Robert Verger
Daniel A. Lawrence, Leif Strandberg, Johan Ericson, and Tor Ny
20302 Human immunodeficiency virus reverse transcrip- tase. Substrate and inhibitor kinetics with thymi- dine 5’-triphosphate and 3’-azido-3’-deoxythymi- dine 5’-triphosphate.
John E. Reardon and Wayne H. Miller
20308 Studies on the mechanism of oxidative phosphoryl- ation. ADP promotion of GDP phosphorylation.
Akemi Matsuno-Yagi and Youssef Hatefi
20314 Translational regulation by steroids. Identification of a steroid modulatory element in the B’-untrans- :a: region of the myelin basic protein messenger
Joseph M. Verdi and Anthony T. Campagnoni
20321 The Gibbs-Donnan near-equilibrium system of heart.
Takashi Masuda, Geoffrey P. Dobson, and Richard L. Veech
20335 A calcium-sensitive fluorescent analog of calmodu- lin based on a novel calmodulin-binding fluoro- phore.
Klaus M. Hahn, Alan S. Waggoner, and D. Lansing Taylor
20346 Intracellular Na+ kinetically interferes with the ro- tation of the Na+-driven flagellar motors of Vibrio alginolyticus.
Satomi Yoshida, Shigeru Sugiyama, Yoshiaki Hojo, Ha- jime Tokuda, and Yasuo Imae
20351 Receptor-mediated calcium influx in PC12 cells. ATP and bradykinin activate two independent pathways.
Cristina Fasolato, Paola Pizza, and Tullio Pozzan
20356 Dissociation of the DNA polymerase III holoenzyme fiz subunits is accompanied by conformational change at distal cysteines 333.
Mark A. Griep and Charles S. McHenry
20364 The liver glucose-6-phosphatase of intact micro- somes is inhibited and displays sigmoid kinetics in the presence of cy-ketoglutarate-magnesium and ox- aloacetate-magnesium chelates.
Gilles Mithieun, Felix V. Vega, and Jean-Paul Riou
20369 Synthetic peptide analogs of DARPP-32 (A& 32,000 dopamine- and CAMP-regulated phosphoprotein), an inhibitor of protein phosphatase- 1. Phosphoryl- ation, dephosphorylation, and inhibitory activity.
Hugh C. Hemmings, Jr., Angus C. Nairn, James I. Elliott, and Paul Greengard
20377 Inactivation of splicing factors in HeLa cells sub- jetted to heat shock.
Ram R. Shukla, Zbigniew Dominski, Tadeusz Zwierzyn- ski, and Ryszard Kole
20384 Active-site residues of 2-keto-4-hydroxyglutarate aldolase from Escherichia coli. Bromopyruvate in- activation and labeling of glutamate 45.
Chris J. Vlahos and Eugene E. Dekker
20390 Molecular cloning of cDNA encoding the C subunit of H’-ATPase from bovine chromaffin granules.
Hannah Nelson, Sreekala Mandiyan, Takato Noumi, Yoshinori Moriyama, May C. Miedel, and Nathan Nelson
iv
20394 Preferential inhibition of the platelet-derived growth factor receptor tyrosine kinase by stauros- porine.
J. Paul Secrist, Inder Sehgal, Garth Powis, and Robert 2’. Abraham
20401 Isolation and primary structure of PARP, a 24-kDa proline- and arginine-rich protein from bovine car- tilage closely related to the N&-terminal domain in collagen (rl(X1).
Peter J. Neame, Carmen N. Young, and James T. Treep
20409 Cleavage specificity of human skin type IV colla- genase (gelatinase). Identification of cleavage sites in type I gelatin, with confirmation using synthetic peptides.
Jo Louise Seltzer, Kathryn T. Akers, Harold Weingarten, Gregory A. Grant, David W. McCourt, and Arthur Z. Eisen
20414 The primary structure of the rat guanylyl cyclase A/atria1 natriuretic peptide receptor gene.
Masaaki Yamaguchi, Laura Jo Rutledge, and David L. Garbers
20421 Disruption of active site interactions with pyridoxal 5’-phosphate and substrates by conservative re- placements in the glycine-rich loop of Escherichia coli D-serine dehydratase.
Michelle Marceau, Sidney D. Lewis, Christopher L. Ko- jiro. Kimberly Mountjoy, and Jules A. Shafer
20430 Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.
Edward Perez-Reyes, Xiangyang Wei, Antonio Castel- lane, and Lutz Birnbaumer
20437 Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP).
Jackson B. Gibbs, Mark S. Marshall, Edward M. Scol- nick, Richard A. F. Dixon, and Ursula S. Vogel
20443 Oxygen radicals generated during anoxia followed by reoxygenation reduce the synthesis of tissue-type piasminogen activator and plasminogen activator inhibitor-l in human endothelial cell culture.
Marie A. Shatos, Jacqueline M. Doherty, David C. Stump, E. Anne Thompson, and Desire Cohen
20449 B Spectrin in human skeletal muscle. Tissue-specific differential processing of 3’ /3 spectrin pre-mRNA generates a @ spectrin isoform with a unique car- boxy1 terminus.
John C. Winkelmann, Fernando F. Costa, Bradley L. Linzie, and Bernard G. Forget
20455 The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localiza- tion, and isolation of cDNA from tracheal and gas- tric tissues.
Norma P. Gerard, Roger L. Eddy, Jr., Thomas B. Shows, and Craig Gerard
20463 Accumulation of the insoluble Pi2 variant of human a,-antitrypsin within the hepatic endoplasmic retic- ulum does not elevate the steady-state level of grp’irS/BiP.
Kathleen S. Graham, Anhquyen Le, and Richard N. Sifers
20469 Characterization of human 3&hydroxysteroid de- hydrogenase/A’-A”-isomerase gene and its expres- sion in mammalian cells.
Yves Lachance, Van Luu-The, Claude Lab&, Jacques Simard, Martine Dumont, Yvan de Launoit. Sylvain Gu&in, Gilles Leblanc, and Fernand Labrie
20476 Granulocytic differentiation of HL-60 cells is asso- ciated with increase of poly-N-acetyllactosamine in Asn-linked oligosaccharides attached to human ly- sosomal membrane glycoproteins.
Ni Lee, Wei-Chun Wang, and Minoru Fukuda
20488 The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp-l and lamp-2. Local- ization on the peptide backbones.
Sven R. Carlsson and Minoru Fukuda
20496
20506
20517
20524
20533
20539
20547
20555
20563
20570
20577
20585
20589
20594
20602
Evidence for a common mechanism of action for antitumor and antibacterial agents that inhibit type II DNA topoisomerases.
Anne C. Huff and Kenneth N. Kreuzer
The growth factor-like effects of tumor necrosis factor-a. Stimulation of glucose transport activity and induction of glucose transporter and immediate early gene expression in 3T3-Ll preadipocytes.
Peter Cornelius. Melissa Marlowe. M. Douelas Lee. and Phillip H. Pekala ’
Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation.
Kirk A. Lund, Cheri S. Lazar, William S. Chen, Brenda J. Walsh, John B. Welsh, John J. Herbst, Gordon M. Walton, Michael G. Rosenfeld, Gordon N. Gill, and H. Steven Wiley
Minimal sequence and factor requirements for the initiation of transcription from an atypical, TATA- TAA box-containing housekeeping promoter.
Thomas G. Boyer and Lynne E. Maquat
Distinct transforming growth factor-8 (TGF-8) receptor subsets as determinants of cellular respon- siveness to three TGF-8 isoforms.
Sela Cheifetz, Helen Hernandez, Marikki Laiho, Peter ten Dijke, Kenneth K. Iwata, and Joan Massagt~?
Accommodation of protein synthesis to chronic dep- rivation of intracellular sequestered calcium. A pu- tative role for GRP78.
Margaret A. Brostrom, Christina Cade, Christopher R. Prostko, Debra Gmitter-Yellen, and Charles 0. Brostrom
Purification and reconstitution of the FIFo-ATP synthase from alkaliphilic Bacillus firmus OF4. Evidence that the enzyme translocates H+ but not Na+.
David B. Hicks and Terry A. Krulwich
Endothelin induction of inositol phospholipid hy- drolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy.
Huda E. Shubeita, Patrick M. McDonough, Adrienne N. Harris, Kirk U. Knowlton, Christopher C. Glembotski, Joan Heller Brown, and Kenneth R. Chien
Mouse opsin. Gene structure and molecular basis of multiple transcripts.
Muayyad R. Al- Ubaidi, Steven J. Pitt& Mary S. Cham- pagne, John T. Triantafyllos, James F. McGinnis, and Wolfgang Baehr
Binding of Na+ ions to the Na,K-ATPase increases the reactivity of an essential residue in the ATP binding domain.
Graham C. R. Ellis-Davies and Jack H. Kaplan
The species-specific cell-binding site of the aggre- gation factor from the snonge Microciona wolifera $ a highly repetitive noveiglycan containing glu- curonic acid, fucose, and mannose.
Gradimir N. Misevic and Max M. Burger
OXBOX, a positive transcriptional element of the heart-skeletal muscle ADP/ATP translocator gene.
Kang Li, Judy A. Hodge, and Douglas C. Wallace
Neoplastic transformation is associated with coor- dinate induction of nuclear and cytoplasmic oxida- tive phosphorylation genes.
Antonio Torroni, Georges Stepien, Judy A. Hodge, and Douglas C. Wallace
A conformation-dependent epitope of human plate- let glycoprotein IIIa.
William C. Kouns, C. Denise Wall, Melanie M. White, Carol F. Fox, and Lisa K. Jennings
Mechanism of corticotropin and CAMP induction of mitochondrial cytochrome P450 system enzymes in adrenal cortex cells.
Israel Hanukoglu, Ruth Feuehtwanger, and Aaron Hanukoglu
20609
20616
20621
20627
20634
20641
20646
20653
20662
20667
Expression of wild-type and mutated forms of the catalytic ((I) subunit of Caenorhabditis elegana cas- ein kinase II in Escherichia coli.
Erding Hu and Charles S. Rubin
Apolipoprotein B messenger RNA editing is devel- opmentally regulated and widely expressed in hu- man tissues.
BaBie Teng, Marion Verp, Julia Salomon, and Nicholas 0. Davidson
Sequence of a cDNA that specifies the uridine di- phosphate N-acetyl-D-glucosamine:dolichol phos- phate N-acetylglucosamine- 1 -phosphate transfer- ase from Chinese hamster ovary cells.
Jane R. Scocca and Sharon S. Krag
Association of cell surface heparan sulfate proteo- &cans of Schwann cells with extracellular matrix proteins.
David J. Carey, Deana M. Crumbling, Richard C. Stahl, and Diane M. Evans
Identification of the keratan sulfate attachment sites on bovine fibromodulin.
Anna H. K. Plaas, Peter J. Neame, Catherine M. Nivens, and Lisa Reiss
Differential recognition of ultraviolet lesions by RecA protein. Possible mechanism for preferential targeting of SOS mutagenesis to (6-4) dipyrimidine sites.
Marcie Rosenberg and Harrison Echo/s
A new Acanthamoeba myosin heavy chain. Cloning of the gene and immunological identification of the polypeptide.
Jill A. Horowitz and John A. Hammer, III
A novel adenylylation process in liver plasma mem- brane-bound proteins.
Esteban San Jo&, Albert0 Benguria, and Antonio Villalobo
Isolation of four core histones from human sperm chromatin representing a minor subset of somatic histones.
Joe M. Gatewood, Gary R. Cook, Rod Balhorn, Carl W. Schmid, and E. Morton Bradbury
Zinc-induced secondary structure transitions in hu- man sperm protamines.
Joe M. Gatewood, Gary P. Schroth, Carl W. Schmid, and E. Morton Bradbury
20673
20678
20686
20692
20699
20708
20713
20713
20713
Cellular processing of the interleukin-2 fusion toxin DABdss-IL-2 and efficient delivery of diphtheria fr;;,yent A to the cytosol of target cells requires
Dian; P. Williams, Zilong Wen, R. Scott Watson, Jessica Boyd, Terry B. Strom, and John R. Murphy
Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol.
Masato Ogata, Vijay K. Chaudhury, Ira Pastan, and David J. FitzGerald
Several regions of human estrogen receptor are in- volved in the formation of receptor-heat shock pro- tein 90 complexes.
Bt!atrice Chambraud, Meera Berry, Gkrard Redeuilh, Pierre Chambon, and Etienne-Emile Baulieu
A&nine 127 stabilizes the transition state in car- bocypeptidase.
Margaret A. Phillips, Robert Fletterick, and William J. Rutter
Binding characteristics of IgA 16.4.123, a mono- clonal antibody with specificity for the nonreducing terminal epitope of a-( 1+6)-dextrans. Comparisons between IgA hybridoma 16.4.123 and myeloma w3129.
Eugenia M. Nashed, Guillermo R. Perdomo,, Eduardo A. Padlan, Pavol KovciE, Tsukasa Matsuda, Elvm A. Kabat, and Cornelis P. J. Glaudemans
Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah recep- tor is heteromeric.
Cornelis J. Elferink, Thomas A. Gasiewicz, and James P. Whitlock, Jr.
ADDITIONS AND CORRECTIONS
Isolation and characterization of a novel large pro- tease accumulated in mammalian cells in the pres- ence of inhibitors. Vol. 264 (1989) 16093-16099.
Akihiko Tsuji and Kotoku Kurachi
A fraction of CD3c subunits exists as disulfide- linked dimers in both human and murine T lympho- cytes. Vol. 265 (1990) 15850-15853.
Yong-Jiu Jin, Shigeo Koyasu, Phili Steinbrich, George E. Tarr, and Ellis
pe Moingeon, Ruth f Reinherz
ATPl 0, a yeast nuclear gene required for the assem- bly of the mitochondrial FI-Fo complex. Vol. 265 (1990) 9952-9959.
Sharon H. Ackerman and Alexander Tzagoloff
xi Cumulative author index. Numbers 1 through 33.
GENERAL INFORMATION
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Vol. 265, No. 33
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The Journal of Biological Chemistry
CONTENTS Arranged by Subject Categories
November 25,199O
MINIREVIEW
Ribonuclease P. Postscript. Sidney Altman
CARBOHYDRATES, LIPIDS, AND OTHER NATURAL PRODUCTS
Sequential degradation of chondroitin sulfate in molluscs. Desulfation of chondroitin sulfate without prior depolymerization by a novel sulfatase from Anomalocardia brasiliana.
J. Felipe de Sousa, Jr., Helena B. Nader, and Carl P. Dietrich
The carbohydrate structures of a mouse monoclonal IgG antibody OKT3.
Hubert Krotkiewski, Gunnar Grbnberg, Bozena Krot- kiewska, Bo Nilsson, and Sigfrid Svensson
Granulocytic differentiation of HL-60 cells is asso- ciated with increase of poly-N-acetyllactosamine in Asn-linked oligosaccharides attached to human ly- sosomal membrane glycoproteins.
Ni Lee, Wei-Chun Wang, and Minoru Fukuda
The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp- 1 and lamp-2. Local- ization on the peptide backbones.
Suen R. Carlsson and Minoru Fukuda
The species-specific cell-binding site of the aggre- gation factor from the sponge Microciona prolifera is a highly repetitive novel glycan containing glu- curonic acid, fucose, and mannose.
Gradimir N. Misevic and Max M. Burger
Sequence of a cDNA that specifies the uridine di- phosphate N-acetyl-D-glucosamine:dolichol phos- phate iV-acetylglucosamine-l-phosphate transfer- ase from Chinese hamster ovary cells.
Jane R. Scocca and Sharon S. Krag
Identification of the keratan sulfate attachment sites on bovine fibromodulin.
Anna H. K. P&s, Peter J. Neame, Catherine M. Nivens, and Lisa Reiss
Binding characteristics of IgA 16.4.123, a mono- clonal antibody with specificity for the nonreducing terminal epitope of cu-(1+6)-dextrans. Comparisons between IgA hybridoma 16.4.123 and myeloma w3129. -
Eugenia M. Nashed, Guillermo R. Perdomo, Eduardo A. Padlan. Pavol Kov& Tsukasa Matsuda. Elvin A. Kabat. and Coknelis P. J. Gk&demans
CELL BIOLOGY AND METABOLISM
Saccharomyces cerevisiae STEl4 gene is required for COOH-terminal methylation of a-factor mating pheromone.
Rachel Sterne Marr, Lindley C. Blair, and Jeremy Thorner
Transcriptional activation of G.a expression by re- tinoic acid and parathyroid hormone-related pro- tein in F9 teratocarcinoma cells.
Samuel D. H. Chan, Gordon J. Strewler, and Robert A. Nissenson
Sorting of peroxisomal membrane protein PMP47 from Candida boidinii into peroxisomal membranes of Saccharomyces cerevisiae.
Mark T. McCammon, Carl A. Dowds, Kim Orth, Carolyn R. Moomaw, Clive A. Slaughter, and Joel M. Goodman
Insulin regulation of hexose transport in mouse 3T3-Ll cells expressing the human HepG2 glucose transporter.
Scott A. Harrison, Joanne M. Buxton, Brian M. Clancy, and Michael P. Czech
20123
20144
20166
20179
20220
20241
20247
20335
20351
20364
20394
20414
20437
20443
Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90.
Edwin R. Sanchez, Margaret Hirst, Lawrence C. Scher- rer, Hsin-Yi Tang, Michael J. Welsh, Jeffrey M. Harmon, S. Stoney Simons, Jr., Gordon M. Ringold, and William B. Pratt
The OLEI gene of Saccharomyces cerevisiae en- codes the A9 fatty acid desaturase and can be func- tionally replaced by the rat stearoyl-CoA desaturase gene.
Joseph E. Stukey, Virginia M. McDonough, and Charles E. Martin
“Suicide” inactivation of thromboxane AZ synthase. Characteristics of mechanism-based inactivation with isolated enzyme and intact platelets.
David A. Jones and F. A. Fitzpatrick
Impaired secretion and fluid-phase endocytosis in the End4 mutant of Chinese hamster ovary cells.
Ru-Hung Wang, Penelope A. Colbaugh, Chia-Yi Kao, Elizabeth A. Rutledge, and Rockford K. Draper
Activation of membrane guanylate cyclase by an invertebrate peptide hormone.
Michael F. Goy
Molecular basis of interferon-y and lipopolysaccha- ride enhancement of phagocyte respiratory burst capability. Studies on the gene expression of several NADPH oxidase components.
Marco A. Cassatella, Flavia Bazzoni, Rebecca M. Flynn, Stefano Dusi, Giorgio Trinchieri, and Filippo Rossi
Mouse fi thalassemia, a model for the membrane defects of erythrocytes in the human disease.
Philippe Rouyer-Fessard, Karen Leroy- Viard, Chuntal Domenget, Amel Mrad, and Yves Beuzard
A calcium-sensitive fluorescent analog of calmodu- lin based on a novel calmodulin-binding fluoro- phore.
Klaus M. Hahn, Alan S. Waggoner, and D. Lansing Taylor
Receptor-mediated calcium influx in PC12 cells. ATP and bradykinin activate two independent pathways.
Cristina Fasolato, Paola Pizzo, and Tullio Pozzan
The liver glucose-6-phosphatase of intact micro- somes is inhibited and displays sigmoid kinetics in the presence of a-ketoglutarate-magnesium and ox- aloacetate-magnesium chelates.
Gilles Mithieux, Felix V. Vega, and Jean-Paul Riou
Preferential inhibition of the platelet-derived growth factor receptor tyrosine kinase by stauros- porine.
J. Paul Secrist. lnder Sehtal, Garth Powis, and Robert T. Abraham
The primary structure of the rat guanylyl cyclase A/atria1 natriuretic peptide receptor gene.
Masaaki Yamaguchi, Laura Jo Rutledge, and David L. Garbers
Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP).
Jackson B. Gibbs, Mark S. Marshall, Edward M. Scol- nick, Richard A. F. Dixon, and Ursula S. Vogel
Oxygen radicals generated during anoxia followed by reoxygenation reduce the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor- 1 in human endothelial cell culture.
Marie A. Shatos, Jacqueline M. Doherty, David C. Stump, E. Anne Thompson, and DZsirti Collen
l Indicates a Communication
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20449
20463
20506
20517
20533
20616
20627
20678
20713
20234
20271
20302
B Spectrin in human skeletal muscle. Tissue-specific differential processing of 3’ JI spectrin pre-mRNA generates a t!? spectrin isoform with a unique car- boxy1 terminus.
John C. Winkelmann, Fernando F. Costa, Bradley L. Linzie, and Bernard G. Forget
Accumulation of the insoluble PiZ variant of human al-antitrypsin within the hepatic endoplasmic retic- ulum does not elevate the steady-state level of grp78/BiP.
Kathleen S. Graham, Anhquyen Le, and Richard N. Sifers
The growth factor-like effects of tumor necrosis factor-a. Stimulation of glucose transport activity and induction of glucose transuorter and immediate early gene expression in 3T3-Ll preadipocytes.
Peter Cornelius, Melissa Marlowe, M. Douglas Lee, and Phillip H. Pekala
Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation.
Kirk A. Lund, Cheri S. Lazar, William S. Chen, Brenda J. Walsh, John B. Welsh, John J. Herbst, Gordon M. Walton, Michael G. Rosenfeld, Gordon N. Gill, and H. Steuen Wiley
Distinct transforming growth factor-8 (TGF-8) receptor subsets as determinants of cellular respon- siveness to three TGF-13 isoforms.
Sela Cheifetz, Helen Hernandez, Marikki Laiho, Peter ten Dijke, Kenneth K. Iwata, and Joan Massague
Apolipoprotein B messenger RNA editing is devel- opmentally regulated and widely expressed in hu- man tissues.
BaBie Teng, Marion Verp, Julia Salomon, and Nicholas 0. Davidson
Association of cell surface heparan sulfate proteo- glycans of Schwann cells with extracellular matrix proteins.
David J. Carey, Deana M. Crumbling, Richard C. Stahl, and Diane M. Evans
Processing of Pseudomonas exotoxin by a cellular urotease results in the generation of a 37,000-Da toxin fragment that is tcanslocated to the cytosol.
Masato Ogata, Vijay K. Chaudhary, Ira Pastan, and David J. FitzGerald
Isolation and characterization of a novel large pro- tease accumulated in mammalian cells in the Dres- ence of inhibitors. Vol. 264 (1989) 16093-16699.
Akihiko Tsuji and Kotoku Kurachi
ENZYMOLOGY
The effect of phosphate and calcium on force gen- eration in glycerinated rabbit skeletal muscle fi- bers. A steady-state and transient kinetic study.
Neil C. Miliar and Earl Homsher
Stereoselectivity of lipases. I. Hydrolysis of enan- tiomeric glyceride analogues by gastric and pan- creatic lipases, a kinetic study using the monomo- lecular film technique.
Stephane Ransac, Ewa Rogalska, Youssef Gargouri, Annemieke M. T. J. Deveer, Fritz Paltauf. Gerard H. de Haas, and Robert Verger
Stereoselectivity of lipases. II. Stereoselective hy- drolysis of triglycerides by gastric and pancreatic lipases.
Ewa Rogalska, Stephane Ransac, and Robert Verger
Human immunodeficiency virus reverse transcrip- tase. Substrate and inhibitor kinetics with thymi- dine 5’-triphosphate and 3’-azido-3’-deoxythymi- dine 5’-triphosphate.
John E. Reardon and Wayne H. Miller
20384
20409
20496
20692
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20210
20308
20321
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vii
Active-site residues of 2-keto-4-hydroxyglutarate aldolase from Escherichia coli. Bromopyruvate in- activation and labeling of glutamate 45.
Chris J. Vlahos and Eugene E. Dekker
Cleavage specificity of human skin type IV colla- genase (gelatinase). Identification of cleavage sites in tvue I gelatin, with confirmation using synthetic peptides.-
Jo Louise Seltzer, Kathryn T. Akers, Harold Weingarten, Gregory A. Grant, David W. McCourt, and Arthur Z. Eisen
Evidence for a common mechanism of action for antitumor and antibacterial agents that inhibit type II DNA topoisomerases.
Anne C. Huff and Kenneth N. Kreuzer
Arginine 127 stabilizes the transition state in car- boxypeptidase.
Margaret A. Phillips, Robert Fletterick, and William J. Rutter
MEMBRANES AND BIOENERGETICS
Minimum substrate sequence for signal peptidase I of Escherichia coli.
Inderjit K. Dev, Paul H. Ray, and Paul Novak
Tyrosine radicals in Photosystem II and related model compounds. Characterization by isotopic labeling and EPR spectroscopy.
Bridgette A. Barry, Mohamed K. El-Deeb, Peter 0. San- dusky, and Gerald T. Babcock
Import of apocytochrome c into the mitochondrial intermembrane space along a cytochrome c, sorting pathway. -
Rosemary A. Stuart, Donald W. Nicholson, Ulla Wien- hues, and Walter Neupert
Studies on the mechanism of oxidative phosphoryl- ation. ADP promotion of GDP phosphorylation.
Akemi Matsuno-Yagi and Youssef Hatefi
The Gibbs-Donnan near-equilibrium system of heart.
Takashi Masuda, Geoffrey P. Dobson, and Richard L. Veech
Intracellular Na+ kinetically interferes with the ro- tation of the Na+-driven flagellar motors of Vibrio alginolyticus.
Satomi Yoshida, Shigeru Sugiyama, Yoshiaki Hojo, Ha- jime Tokuda, and Yosuo Imae
Molecular cloning of cDNA encoding the C subunit of H+-ATPase from bovine chromaffin granules.
Hannah Nelson, Sreekala Mandiyan, Takato Noumi, Yoshinori Moriyama, May C. Miedel, and Nathan Nelson
Purification and reconstitution of the FIFo-ATP synthase from alkaliphilic Bacillus firmus OF4. Evidence that the enzyme translocates H+ but not Na’.
David B. Hicks and Terry A. Krulwich
A novel adenylylation process in liver plasma mem- brane-bound proteins.
Esteban San Jose, Albert0 Benguria, and Antonio Villalobo
ATPI 0, a yeast nuclear gene required for the assem- bly of the mitochondrial F,-F, complex. Vol. 265 (1990) 9952-9959.
Sharon H. Ackerman and Alexander Tzagoloff
NUCLEIC ACIDS, PROTEIN SYNTHESIS, AND MOLECULAR GENETICS
-20061
-20065
Molecular cloning of the fMet-Leu-Phe receptor from neutrophils.
Kathleen M. Thomas, Hae Yung Pyun, and Javier Navarro
Mapping of a retinoic acid-responsive element in the promoter region of the complement factor H gene.
Pura Muiioz-Canoves, Dennis P. Vik, and Brian F. Tack
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20160
20172
20188
20277
20285
20314
20356
20377
20455
20469
20524
Molecular cloning by hybrid arrest of translation in Xenopue laeuis oocytes. Identification of a cDNA encoding the type I iodothyronine 5’-deiodinase from rat liver.
Donald L. St. Germain, Walburga Dittrich, Christine M. Morganelli, and Vincent Cryns
HIV-1 tat gene induces tumor necrosis factor-6 (lymphotoxin) in a human B-lymphoblastoid cell line.
K. Jagannadha Sastry, Raghava H. R. Reddy, Raj Pan- d&a, Klara Totpal, and Bharat B. Aggarwal
Sequence specificity of mRNA p-adenosine meth- yltransferase.
Tunde Csepany, Alison Lin, Carl J. Baidick, Jr., and Karen Beemon
Increased levels of junB and c-.jun mRNAs in male germ cells following testicular cell dissociation. Maximal stimulation in prepuberal animals.
Acacia A. Alcivar, Laura E. Hake, Matthew P. Hardy, and Norman B. Hecht
Mechanisms of inhibition of herpes simplex virus type 2 growth by 28-mer phosphorothioate oligo- deoxycytidine.
Wen-Yi Gao, Jerzy W. Jaroszewski, Jack S. Cohen, and Yung-Chi Cheng
Protein factors that bind to the murine 2’,5’-oli- goadenylate synthetase ME-12 gene 5’ upstream regulatory region.
Gong Yan and Igor Tamm
Structural and functional analysis of the human thymidylate synthase gene.
Sumiko Kaneda, Josephine Nalbantogly Keiichi Take- ishi, Kimiko Shim& Osamu Gotoh, Takeshi Seno, and Dai Ayusawa
Cellular factors involved in transcription and Tax- mediated trans-activation directed by the TGACGT motifs in human T-cell leukemia virus type I pro- moter.
Yi-Ling Xu, Neeraj Adya, Eric Siores, Qingsheng Gao, and Chou-Zen Giam
Translational regulation by steroids. Identification of a steroid modulatory element in the 5’-untrans- lated region of the my&n basic protein messenger RNA.
Joseph M. Verdi and Anthony T. Campagnoni
Dissociation of the DNA polymerase III holoenzyme f12 subunits is accompanied by conformational change at distal cysteines 333.
Mark A. Griep and Charles S. McHenry
Inactivation of splicing factors in HeLa cells sub- jected to heat shock.
Ram R. Shukla, Zbigniew Dominski, Tadeussz Zwierzyn- ski, and Ryszard Kole
The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localiza- tion, and isolation of cDNA from tracheal and gas- tric tissues.
Norma P. Gerard, Roger L. Eddy, Jr., Thomas B. Shows, and Craig Gerard
Characterization of human S&hydroxysteroid de- hydrogenase/A6-A4-isomerase gene and its expres- sion in mammalian cells.
Yves Lachance, Van Luu-The, Claude Labrie, Jacques Simard, Martine Dumont, Yvan de Launoit, Sylvain Gtirin, Gilles Leblanc, and Fernand Labrie
Minimal sequence and factor requirements for the initiation of transcription from an atypical, TATA- TAA box-containing housekeeping promoter.
Thomas G. Boyer and Lynne E. Maquat
20539
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20563
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20589
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20609
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20646
20686
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Accommodation of protein synthesis to chronic dep- rivation of intracellular sequestered calcium. A pu- tative role for GRP78.
Margaret A. Brostrom, Christina Cade, Christopher R. Prostko, Debra Gmirter- Yellen, and Charles 0. Brostrom
Endothelin induction of inositol phospholipid hy- drolysis, sarcomere assembly, and cardiac gene expresslon in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy.
Huda E. Shubeita, Patrick M. McDonough, Adrienne N. Harris, Kirk U. Knowlton, Christopher C. Glembotski, Joan Heller Brown, and Kenneth R. Chien
Mouse opsin. Gene structure and molecular basis of multiple transcripts.
Munyyad R. Al-Ubaidi, Steven J. Pittler, Mary S. Cham- pagne, John T. Triantafyllos, James F. McGinnis, and Wolfgang Baehr
OXBOX, a positive transcriptional element of the heart-skeletal muscle ADP/ATP translocator gene.
Kang Li, Judy A. Hodge, and Douglas C. Wallace
Neoplastic transformation is associated with coor- dinate induction of nuclear and cytoplasmic oxida- tive phosphorylation genes.
Antonio Torroni, Georges Stepien, Judy A. Hodge, and Douglas C. Wallace
Mechanism of corticotropin and CAMP induction of mitochondrial cytochrome P450 system enzymes in adrenal cortex cells.
Israel Hanukoglu, Ruth Feuchtwanger, and Aaron Hanukoglu
Expression of wild-type and mutated forms of the catalytic (a) subunit of Caenorhabditis elegans cas- ein kinase II in Escherichia coli.
Erding Hu and Charles S. Rubin
Differential recognition of ultraviolet lesions by RecA protein. Possible mechanism for preferential targeting of SOS mutagenesis to (6-4) dipyrimidine sites.
Marcie Rosenberg and Harrison Echols
A new Acanthamoeba myosin heavy chain. Cloning of the gene and immunological identification of the polypeptide.
Jill A. Horowitz and John A. Hammer, III
Several regions of human estrogen receptor are in- volved in the formation of receptor-heat shock pro- tein SO complexes.
BPatrice Chambraud, Meera Berry, Gdrard Redeuilh, Pierre Chambon, and Etienne-Em& Baulieu
Protein-DNA interactions at a dioxin-responsive enhancer. Evidence that the transformed Ah recep- tor is heteromeric.
Cornelis J. Elferink, Thomas A. Gasiewicz, and James P. Whitlock, Jr.
PROTEIN CHEMISTRY AND STRUCTURE
Tyrosine 385 of prostaglandin endoperoxide syn- thase is required for cyclooxygenase catalysis.
Teruhiko Shimokawa, Richard J. Kulmacz, David L. Dewitt, and William L. Smith
Immunochemical analysis of the exposure of high mobility group protein 14 and 17 surfaces in chro- matin.
Michael Bustin, Massimo P. Crippa, and James M. Pash
Isolation of subtilisin pro-sequence mutations that affect formation of active protease by localized ran- dom polymerase chain reaction mutagenesis.
Claude G. Lerner, Tatsuhiko Kobayashi, and Masayori Inouye
a-Dendrotoxin acceptor from bovine brain is a K+ channel protein. Evidence from the N-terminal se- quence of its larger subunit.
Victoria E. S. Scott, David N. Parcej, Jeffrey N. Keen, John B. C. Findlay, and J. Oliuer Dolly
l Indicates a Communication
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20131 Purification and partial amino acid sequence analy- sis of two distinct tumor necrosis factor receptors from HL60 cells.
Hansruedi Loetscher, Ernst J. Schlaeger, Hans- Werner Lahm, Yu-Ching E. Pan, Werner Lesslauer, and Manfred Brockhaus
20156 Further localization of binding sites for thrombin and protein C in human thrombomodulin.
Tatsuya Hayashi, Michitaka Zushi, Shuji Yamamoto, and Koji Suzuki
20202 Channel formation properties of synthetic pardaxin and analogues.
Yechiel Shai, Diana Bach, and Aliza Yanovsky
20228 Amino acid substitutions Pheee - Leu and Ser12’ -+ Pro abolish cortisol and aldosterone synthesis by bovine cytochrome P450, i,+
Porunelloor A. Mathew, J. Ian Mason, John M. Trant, Donita Sanders, and Michael R. Waterman
20252 Biochemical study of a recombinant soluble inter- leukin-2 receptor. Evidence for a homodimeric structure.
Yannick Jacques, Brigitte Le Mauff, Anne Godard, Jeanne Naulet, Michael Concino, Henry Marsh, Stephen Ip, and Jean-Paul Soulillou
20259 Purification and structure of exendin-3, a new pan- creatic secretagogue isolated from Heloderma hor- ridum venom.
John Eng, P. C. Andrews, Wayne A. Kleinman, Latika Singh, and Jean-Pierre Raufman
20293 Structure-function studies of the SERPIN plasmin- ogen activator inhibitor type 1. Analysis of chimeric strained loop mutants.
Daniel A. Lawrence, Leif Strandberg, Johan Ericson, and Tor Ny
20369 Synthetic peptide analogs of DARPP-32 (M, 32,000 dopamine- and CAMP-regulated phosphoprotein), an inhibitor of protein phosphatase- 1. Phosphoryl- ation, dephosphorylation, and inhibitory activity.
Hugh C. Hemmings, Jr., Angus C. Nairn, James I. Elliott, and Paul Greengard
20401
20421
20430
20570
20594
20662
20667
20673
20713
Isolation and primary structure of PARP, a 24.kDa proline- and arginine-rich protein from bovine car- tilage closely related to the NHz-terminal domain in collagen crl (XI).
Peter J. Neame, Carmen N. Young, and James T. Treep
Disruption of active site interactions with pyridoxal W-phosphate and substrates by conservative re- placements in the glycine-rich loop of Escherichia coli D-serine dehydratase.
Michelle Marceau, Sidney D. Lewis, Christopher L. Ko- jiro, Kimberly Mountjoy, and Jules A. Shafer
Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.
Edward Perez-Reyes, Xiangyang Wei, Antonio Castel- lano, and Lutz Birnbaumer
Binding of Na+ ions to the Na,K-ATPase increases the reactivity of an essential residue in the ATP binding domain.
Graham C. R. Ellis-Davies and Jack H. Kaplan
A conformation-denendent enitone of human plate- let glycoprotein II&. - -
William C. Kouns, C. Denise Wall, Melanie M. White, Carol F. Fox, and Ltsa K. Jennings
Isolation of four core histones from human sperm chromatin representing a minor subset of somatic histones.
Joe M. Gatewood, Ga Schmid, and E. Morton %
R. Cook, Rod Balhorn, Carl W. radbury
Zinc-induced secondary structure transitions in hu- man sperm protamines.
Joe M. Gatewood, Gary P. Schroth, Carl W. Schmid, and E. Morton Bradbury
Cellular processing of the interleukin-2 fusion toxin DAB,,,-IL-2 and efficient delivery of diphtheria fragydent A to the cytosol of target cells requires Arg
Diane P. Williams, Zilong Wen, R. Scott Watson, Jessica Boyd, Terry B. Strom, and John R. Murphy
A fraction of CD3e subunits exists as disulfide- linked dimers in both human and murine T lympho- cytes. Vol. 265 (1990) 15850-15853.
Yong-Jiu Jin, Shigeo Koyasu, Phili pe Moingeon, Ruth Steinbrich, George E. Tarr, and Ellis f Remherz