vesicular eruptions of the oral mucousa · primary herpetic gingivostomatitis • childhood, teens...

35

VESICULAR ERUPTIONS OF THE ORAL MUCOUSA

Upload: others

Post on 03-Jul-2020

4 views

Category:

Documents

0 download

Report

Download

Embed Size (px):

TRANSCRIPT

Page 1: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

VESICULAR ERUPTIONS OF THE

ORAL MUCOUSA

Page 2: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Febrile Associated Vesicles

• Primary Herpetic Gingivostomatitis• Varicella-Zoster• Enterovirus stomatitis• Hand Foot and Mouth Disease• Herpangina

Page 3: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Herpetic Gingivostomatitis

• Childhood, Teens• 99% of population, subclinical• 1% of the population, Primary disease• The “tetralogy” of signs and symptoms

– Fever, lymphadenopathy, gingival lesions, movable mucosa lesions

• Infectious for 5 days, heal 7-8 days• Robust immune response• Establish latency in trigeminal ganglion

– Both primary and subclinical infections

Page 4: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Herpetic Gingivostomatitis

Page 5: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Herpetic Gingivostomatitis

Page 6: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Herpes

Page 7: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Herpetic Gingivostomatitis

Page 8: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Herpes CytologyBallooning Degeneration

Page 9: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Herpes, Viral Antigen

Page 10: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Herpes, Viral DNA

Page 11: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Varicella Zoster• Primary Chicken Pox

– Cutaneous Vesicular Rash– Childhood Immunization

• Recurrent Shingles (Zoster)– Follow entire nerve distribution– Abrupt cessation at midline– May persist for three weeks– Recurrences– Post-herpetic Neuralgia,

Chronic

Page 12: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Varicella (Chichen Pox)

Page 13: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Primary Varicella (Chichen Pox)

Page 14: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Zoster, Ophthalmic Division

Page 15: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Zoster, Maxillary Division

Page 16: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Zoster, Mandibular Division

Page 17: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Enteroviruses• Include ECHO and Coxsackies• No latency• Numbered genotypes and serotypes• Fever, Malaise and Diarrhea• Typing by Stool Culture• Paliative Treatment, 10 day course• Foor oral vesicular syndromes

– Nonspecific enterovirus vesicular stomatitis– Herpangina– Hand Foot and Mouth Disease– Acute Lymphonodular Pharyngitis

Page 18: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

The Enteroviruses

Page 19: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Enterovirus Stomatitis

Page 20: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Hand Foot and Mouth Disease

Page 21: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Hand Foot and Mouth Disease

Page 22: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Herpangina

Page 23: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Herpangina

Page 24: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

NonFebrile Associated Vesicles

• Herpes Labialis• Intraoral Recurrent Herpes• Allergic Stomatitis

Page 25: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Herpes Labialis

Page 26: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Herpes Labialis, Crust

Page 27: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Recurrent Intraoral Herpes

Page 28: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Recurrent Intraoral Herpes

Page 29: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Treatment for HSV and VZV

HSV Active Disease• Infectious for 5 days• Topicals not effective• Systemic effective

only if given first day of infection

VZV Active Disease• Systemic Antivirals

Prophylaxis• Systemic

administration• Rx prior to

precipitating events• Continue 7-10 days

Page 30: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

HSV,VZV Therapy

• Acyclovir• Side groups

– Alter Bioavailability– Alter Half Life

• Topicals• Oral Systemic

Page 31: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Therapy

Page 32: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Therapy

Page 33: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Allergic Vesicular Stomatitis

• Immediate (IgE) hypersensitivity• Immune complex hypersensitivity• Diffuse oral vesiculoulcerative lesions• Afebrile• Painful• Antihistamine/Steroid Responsive

Page 34: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

Allergic Stomatitis (Shell Fish)

Page 35: VESICULAR ERUPTIONS OF THE ORAL MUCOUSA · Primary Herpetic Gingivostomatitis • Childhood, Teens • 99% of population, subclinical • 1% of the population, Primary disease •

DIAGNOSIS BY LOCATION• Primary Herpetic Gingivostomatitis

– Gingival, Movable mucosa• Herpes Labialis

– Clustered lip, ala of the nose• Recurrent Intraoral Herpes

– Clustered palatine, mental, long buccal

• Chichen pox– Diffuse over abdomen, oral

• Shingles– Follow entire nerve (dermatome)

• Hand Foot and Mouth Disease– Movable mucosa, hands, feet

• Herpangina– Soft Palate

Management of Acute (Primary) Herpetic Gingivostomatitis in … · Primary HSV-1 infection usually manifests in the oral cavity so it is important for the dentist to recognize the

Creating a primary ‘Healthy Active Lifestyles’ offer for our inactive student population.

Population receptive field analysis of the primary visual ... · Population receptive field analysis of the primary visual cortex complements ... Aalen Unive rsity of Applied

Primary Health Care PCN - Lakeland Primary Care Network · Primary Care Network (PCN) Information . This section contains information (demographics, First Nations/lnuit population

Population Coverage and Sample Participation Rates · POPULATION COVERAGE AND SAMPLE PARTICIPATION RATES ... when they turn 4 and primary education at age 6, ... POPULATION COVERAGE

Ministry of Health and Population Preventive and Primary Health Care Sector Ministry of Health and Population Preventive and Primary Health Care Sector

Population Health in Primary Care: Cost, Quality, and ...€¦ · 10 / 09.17 The American Journal of Accountable Care® ORIGINAL RESEARCH Population Health in Primary Care: Cost,

Primary Surgery vs Chemoradiotherapy for advanced oropharyngeal cancer: a longitudinal population study

Feline Lymphoplasmacytic Gingivostomatitis: Clinical and

Integrating Behavioral Health into Primary Care – Thought Leaders in Population Health

San Luis Primary Care Area (PCA) 2019 STATISTICAL PROFILE · Primary Care Area #89 San Luis DEMOGRAPHICS POPULATION 46,955 San Luis COUNTY HEALTH PLANNING REGION ARIZONA Population

Primary Hyperparathyroidism in the Geriatric Population

Indigenous Population and Differences in Access to Primary

Population receptive field analysis of the primary visual cortex ... · Population receptive field analysis of the primary visual cortex complements perimetry in patients with homonymous

The Primary Care–Population Medicine Program: A Combined

Investing in Primary Care - Patient Centered Primary Care ... · primary care investment without growing overall health care spending. State leaders are focused on furthering population

Normal narrowing Yf - BMJ · Acuteherpetic gingivostomatitis Primary infection ofthe mucousmembranesofthe mouthis the commonestinfection with herpes simplex in childhood. It usually

Primary Care for Hyndburn’s BME Population

Insert Your Name. Mission: Primary population: Secondary population:

Population need for primary eye care in Rwanda: A national survey · 2019-08-20 · RESEARCH ARTICLE Population need for primary eye care in Rwanda: A national survey Tess Bright1,2*,

(HSV1+2) IgG ab108741 – virus Type 1 and 2 Anti-Herpes ......Primary: Herpetic gingivostomatitis Complications are herpetic keratitis and encephalitis Recurrent form: herpes labialis

Polymicrobial infection of the oral mucosa after ... · acute herpetic gingivostomatitis affects the intrao-ral region when it is primary, whereas secondary infection usually affects

March 4, 2011. HSV GINGIVOSTOMATITIS HSV Gingivostomatitis Most common manifestation of primary HSV infection children – 13-30% Typically HSV-1 Age

BÙI NGUYỄN ĐOAN THƯbenhviennhi.org.vn/upload/files/ACYCLOVIR IN THE... · 2017-11-23 · Primary herpetic gingivostomatitis : commonly seen (85%), typically occurs in children

GINGIVITIS: CATARRHAL, NECROTIZING ULCERATIVE ... › ... › V_Nicolaiciuc_Y4S8L7_8_GINGIVITIS.p… · Chronic periodontitis. Desquamative gingivitis. Spreptococcal gingivostomatitis

Primary Census Abstract for Slum Population

Optimizing Population Health through Risk-Stratification ... Hong Presentation - FINAL.pdfOptimizing Population Health through Risk-Stratification & Team-based Primary Care Clemens

North Coast Primary Health Network General Population

Developing Population Health Clinical Informatics System Requirements to Support Primary Care Delivery and Quality Improvement Developing Population Health

III. CALCULATING POPULATION TO PROVIDER RATIOS Primary Care III-1

Primary Care HPSA Designations - Delaware · Type of HPSA Geographical Area Low Income Population Primary Care HPSA Designations

Advancing Population Health and Primary Care Transformation via

Introduction to pediatric Dentistry - psau.edu.sa...Primary Herpetic Gingivostomatitis is the most frequent acute viral infection on the oral mucosa. Etiology: herpes simplex virus

Population Based Care: The Heart of the Primary Care Behavioral Health Model

Makalah Acute Herpetic Gingivostomatitis dan Perikoronitis