Torq SR (Tolterodine Tartrate Capsules)

Tolterodine Tartrate Capsules

Clearsky Pharmacy

Torq SR (Tolterodine Tartrate Capsules) is used to treat an overactive bladder with symptoms of urinary frequency, urgency, and incontinence. Tolterodine reduces spasms of the bladder muscles.

Torq SR Capsules

Clearsky Pharmacy

Torq SR capsules are manufactured by Dr. Reddy's Laboratories (Website: www.drreddys.com)

Tolterodine Tartrate Capsules Brand Names

Clearsky Pharmacy

Tolterodine Tartrate Capsules are available as Detrol LA, Terol, Terol-LA, Torq SR, Detrusitol, Roliflo OD, Roliten and Urotel-XL.

Active Ingredient

Clearsky Pharmacy

The active ingredient contained in Torq SR capsules is Tolterodine Tartrate.

Chemical Structure

Clearsky Pharmacy

The structure of Tolterodine Tartrate is given below:

Uses of Tolterodine Tartrate Capsules

Clearsky Pharmacy

Torq SR Capsules contain Tolterodine, a muscarinic receptor antagonist and are used for symptomatic treatment of urinary incontinence.

Tolterodine Tartrate Capsules Dosage

Clearsky Pharmacy

The recommended dose of Tolterodine Tartrate Sustained-Release capsules is 4 mg once daily with water and swallowed whole. The dose may be lowered to 2 mg daily based on individual response and tolerability.

The dosage of Torq SR capsules (Tolterodine Tartrate) is given below:

Storage Instructions

Clearsky Pharmacy

Torq SR (Tolterodine Tartrate Capsules) have to be stored at controlled room temperature i.e. from 20C to 25C (68F to 77F) in a cool dry place. Keep this as well as all other medicines away from children and pets.

Warnings

Clearsky Pharmacy

Anaphylaxis and angioedema requiring hospitalization and emergency medical treatment have taken place with the first or subsequent doses of Tolterodine Tartrate sustained-release capsules. Urinary Retention: use caution in patients with clinically significant bladder outflow obstruction because of the risk of urinary retention. Gastrointestinal Disorders: use caution in patients with gastrointestinal obstructive disorders or decreased gastrointestinal motility because of the risk of gastric retention. Controlled Narrow-Angle Glaucoma: use caution in patients being treated for narrow-angle glaucoma.

Warnings

Clearsky Pharmacy

Central Nervous System Effects: Somnolence has been reported with tolterodine tartrate extended-release capsules. Patients must be advised not to drive or operate heavy machinery until they know how Tolterodine Tartrate sustained-release capsules affect them.Myasthenia Gravis: use caution in patients with myasthenia gravis. QT Prolongation: Doctors should consider observations from the thorough QT study in deciding whether to prescribe tolterodine tartrate extended-release capsules to patients with a known history of QT prolongation or to patients who are taking Class IA (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic medications.

Torq SR Capsules

Clearsky Pharmacy

Contraindications

Torq SR capsules are contraindicated in patients with a hypersensitivity to Tolterodine Tartrate or any other component of this medication. They are also contraindicated in patients with urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma. Tolterodine tartrate sustained release capsules are also contraindicated in patients with known hypersensitivity to Fesoterodine Fumarate extended-release tablets which, like Tolterodine Tartrate extended-release capsules, are metabolized to 5-Hydroxymethyl Tolterodine.

Tolterodine Tartrate Side Effects

Clearsky Pharmacy

The common side effects reported by patients receiving Tolterodine Tartrate Sustained-release capsules were dry mouth, headache, constipation, and abdominal pain.

The following side effects were reported post marketing:

General: anaphylaxis and angioedema; Cardiovascular: tachycardia, palpitations, peripheral edema; Gastrointestinal: diarrhea; Central/Peripheral Nervous: confusion, disorientation, memory impairment, hallucinations.

Tolterodine Tartrate Overdose

Clearsky Pharmacy

Overdosage with Tolterodine Tartrate Sustained-Release capsules can potentially result in severe central anticholinergic effects and should be treated accordingly.

Torq SR Capsules Overdose

Clearsky Pharmacy

ECG monitoring is recommended in the event of Torq SR Capsules overdosage. During clinical trials of normal volunteers and patients, QT interval prolongation was observed with Tolterodine immediate-release at doses up to 8 mg (4 mg bid) and higher doses were not evaluated.

Tolterodine Tartrate Capsules During Pregnancy

Clearsky Pharmacy

Torq SR (Tolterodine Tartrate Capsules) has been classified by the US FDA as Pregnancy Category C. During controlled studies in mice, Tolterodine has been shown to be embryolethal and reduce fetal weight, and increase the incidence of fetal abnormalities (cleft palate, digital abnormalities, intra-abdominal hemorrhage, and various skeletal abnormalities, primarily reduced ossification). There are no studies of Tolterodine Capsules in pregnant women. Therefore, Torq SR (Tolterodine Tartrate Capsules) should be used during pregnancy only if the potential benefit for the mother justifies the potential risk to the fetus.

Torq SR Capsules

For more details on Torq SR Capsules click here

Clearsky Pharmacy

Torq SR Capsules (Tolterodine Tartrate Capsules) by Dr. Reddy's Laboratories Limited, India.