The Huigens Lab

March 2014

Huigens Lab Discovery Cycle

Discovery

Cycle

Huigens Lab First Publication

Org. Biomol. Chem. 2014, 12, 881-886.

Nicholas Paciaroni

Medicinal Chemistry Graduate Student

B.S. in Chemistry

Clemson University

(joined: 7/2013)

Focus: Synthetic Organic Chemistry

and Microbiology

Aaron Garrison

College of Pharmacy

Graduate School Fellow

Medicinal Chemistry Graduate Student

B.S. in Biochemistry

University of South Florida

(joined: 8/2013)

Focus: Synthetic Organic Chemistry

The Wrecking Crew

Hussain Yousaf

Undergraduate Researcher

Biology Major

(joined: 1/2014)

Focus: Microbiology

Yasmeen Abouelhassan

Medicinal Chemistry Graduate Student

B.S. Pharmacy

Cairo University

(joined: 2/2014)

Focus: Microbiology

Bacterial Biofilms Underway!!

S. aureus

S. epidermidis

A. baumannii

P. aeruginosa P. aeruginosa

A. baumannii

S. epidermidis

S. aureus

potent biofilm inhibitorbiofilm inhibitor

vehicle control

inactive compound

inactive compound

inactive compoundinactive compound

inactive compound

Bacterial biofilms can be stained with a solution of crystal violet

Bacterial Biofilm Inhibition Assay