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The Holmes Lab

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Page 1: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

The Holmes Lab

Page 2: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

GUT MICROBIOLOGY

Holmes Lab

INTEGRONS

COPPER MEMBRANE MONOOXYGENASES

• Effect of diet on gut microbes

• Impact on human health

• Why do some people lose weight and others can’t?

Page 3: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

GUT MICROBIOLOGY

Holmes Lab

INTEGRONS

COPPER MEMBRANE MONOOXYGENASES

• Horizontal gene transfer in impacted environments

Page 4: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

GUT MICROBIOLOGY

Holmes Lab

INTEGRONS

COPPER MEMBRANE MONOOXYGENASES

• MO activity, substrate pref.

• Applications (monitoring climate change, bioremediation)

Page 5: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

Dr Eline Klaassens – Post Doc• Likes: Yoga• Dislikes: Traffic

#QIIME #454 sequencing #metagenomics

Team Gut

Chau Le – PhD student • Likes: Brunch• Dislikes: Mondays

#histology (staining, embedding)#microscopy

Page 6: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

Connie Ha – PhD student • Likes: Pigs/Korean food

#mouse poo#DGGE#bioinformatics#pyrosequencing

Feyza Colakoglu – PhD student • Likes: Shopping• Dislikes: Staring at the computer

#DGGE#cell culture#culling mice

Page 7: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

Jayden Huynh – our new Honours student! • Likes: Good Music• Dislikes: Bad Music

#bioinformatics#mice work

Colon

Cecum

Page 8: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

Team integronMia Zeric – PhD student • Likes: Running• Dislikes: Southern hyb

#southern hyb#fosmid libraries#natural transformation

Laura Woolfenden – PhD student • Likes: Chocolate• Dislikes: Politics/absence of chocolate

#PCR of all kinds#fosmid libraries#bacterial cultivation

Page 9: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

Team enviromental CuMMOsElissa Liew – Research Assistant• Likes: Singing• Dislikes: Spiders #gas chromatography#cloning#enrichment/isolation#bioremediation#mycobacteria

Page 10: The Holmes Lab. GUT MICROBIOLOGY Holmes Lab INTEGRONS COPPER MEMBRANE MONOOXYGENASES Effect of diet on gut microbes Impact on human health Why do some

The Holmes lab, wanting obese people and the environment to be healthy...