the dangerous patient david mays, md, phd [email protected]

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The Dangerous Patient David Mays, MD, PhD [email protected]

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Page 1: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

The Dangerous Patient

David Mays, MD, [email protected]

Page 2: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Predicting Violence

• Risk assessment is a field of inquiry with a growing literature over the last 20 years. Predicting violence in potential offenders has been the “Holy Grail” of forensic psychiatry.

• Unfortunately, mental health professionals are only a little better than chance at predicting who will be dangerous.

Page 3: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Actuarial Data

• .Various actuarial instruments have been developed to try to assess violence risk (VRAG, LSI-R, HCR-20, etc.) Their accuracy is better than chance, but not good enough to be of practical use in a clinical setting.

Page 4: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Data About Dangerousness

• The best data show that patients with the most serious mental illnesses (schizophrenia, major depression, and bipolar disorder) are 2-3x more likely to be assaultive as the general population. (The lifetime prevalence of violence among the mentally ill is 16%, vs. 7% among the general population.)

• People who abuse alcohol and other drugs are 7x more likely to be assaultive.

Page 5: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Rates of Violence (Fazel S, et al. JAMA May 20, 2009)

Series10.0%

5.0%

10.0%

15.0%

20.0%

25.0%

30.0%

Gen popSchizSchiz + AODA

Page 6: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Violent Individuals in the General Population

General Population

ViolentNonviolent

Page 7: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Violent Individuals in the Mentally Ill Population

Mentally Ill

Page 8: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Violent Individuals in the Substance Abuse Population

Substance Abusers

ViolentNonviolent

Page 9: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

10 Static Risk Factors for ViolenceCarlat Psychiatry Report March 2013

• History of violence• Male gender• Late teens, early 20’s• Below average IQ• Low socioeconomic status• Instability in housing or employment• History of property destruction• Substance abuse• Mental illness• Personality disorder (antisocial, borderline)

Page 10: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

10 Dynamic Risk Factors for ViolenceCarlat Psychiatry Report March 2013

• Intoxication• Withdrawal• Psychotic symptoms• Command hallucinations• Persecutory delusions• Paranoia• Physical agitation• Verbal aggression• Access to weapons• Anger (in response to narcissistic injury)

Page 11: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Screening Military Veterans(Am J Psych Jul 2014)

• The following are related to risk for subsequent violence, and are additive, i.e. combinations of factors have more predictive power. Subjects were followed for 1 year:– Financial instability– Combat experience (witnessing serious injury)– Alcohol misuse– History of noncombat violence or arrest for crime– PTSD + past week irritability

Page 12: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

A Risky Profile

• Young adults with severe mental illness, with trauma and violence in the past, substance abuse in the present, and no interest in treatment in the future.

• (In one small study, patient’s own assessment of their risk of becoming violent was a better predictor than two other assessment tools.)

Page 13: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Gun Deaths in the USA

SuicideHomcideMass Killing

18,00012,000

1000

Page 14: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Homicide vs. Suicide

• Homicide rates have decreased by half (9.8 – 4.8/100,000) over the last 20 years. Suicide rates have remained the same – 12/100,000.

• There are 38,000 suicides per year in the US. There are 14,000 homicides.

• 32 college students were murdered at Virginia Tech in 2007. 32 college students died of suicide last week.

• 90% of suicides are mentally ill. <5% of murderers are mentally ill.

Page 15: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Mental Illness + Guns = Suicide

• The strongest link between mental illness and guns is suicide, not homicide.

• Homicide is more an urban phenomenon. Suicide is more of a rural phenomenon.

• “Means restriction” works for suicide prevention. Ironically, the strongest resistance to means restriction (controlling guns) for suicide is among rural populations. And rural states have the highest suicide rates.

Page 16: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Gun Homicide and Mental Illness

• Even if we cured all mental illness overnight, the rate of gun homicide would essentially remain the same.

Page 17: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

What About Mass Shootings?

• Mass shootings involve the killing of multiple people, followed by the pre-planned suicide of the shooter(s). Often the victims are strangers.

• More often than not, psychological autopsies of these killers describe them as having a mental illness.

• 35 states, including Wisconsin, have increased mental health funding in an effort to prevent mass shootings.

Page 18: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

The $30 Million Wisconsin Plan to Reduce Gun Violence

• Crisis Intervention team training• Child psychiatry consultation program• Grants to doctors in under-served areas• Peer-run respite centers• Treatment and diversion• Job placement and support• Mobile Crisis teams• New units at Mendota Mental Health Institute

Page 19: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Can We Identify a Potential Mass Shooter?

• Possibly, in a few cases. But mass murder is a multi-determined event with no simple preventive solution. They are exceptionally hard to anticipate and avert.

Page 20: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Can We Identify a Potential Mass Shooter?

• The most likely profile is of a suicidal person who is angry, paranoid, and delusional, with a history of prior violence and substance abuse. Common themes that arise in these murderers is social persecution, envy, and a desire for retribution and revenge. They often seek a theatrical event, so they may videotape themselves, alert an audience on the internet, etc.

Page 21: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Anti-Stigma Alert:

• In all studies, mental illness is much weaker predictor of violence than:– A history of violence– Substance abuse

Page 22: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Risk Factors for Violence• In the early years, parenting factors are the most

important risk factor. For teenagers, peer relationships are more important. Mental health problems turn out to be rather poor predictors of future violence.

• Conduct Disorder: Conduct disorder first appearing at 6 years old doubles the risk of criminal adult antisocial behavior (71%), compared to those children who first develop conduct disorder at 12 years old.

Page 23: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Risk Factors for Violence• Firearms are the single greatest risk factor. 28% of

families keep guns at home, 39% are unlocked or loaded or both.

• Alcohol - 40% of all 15-24 year old homicide victims are intoxicated.

• Bullying/Standby Behavior - 7-16% of schoolchildren are bullied in any given semester. Bullying is worst in rural schools. Bullies are 6x more likely to have a criminal conviction by 24, as well as AODA problems. Victims experience social and emotional isolation.

Page 24: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Risk Factors for Violence

• Mental illness: up to 60% are diagnosed. Also includes violent preoccupation, chronic humiliation, grandiosity, lack of empathy. ADHD is also linked to adult antisocial personality disorder and substance abuse, although not as strongly as conduct disorder. When combined with conduct disorder, ADHD becomes a more ominous predictor of bad outcome.

• Media: controversial, but especially influential in vulnerable children

• Families who are dismissive and permissive: too much privacy, parents are afraid of the child.

Page 25: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Risk Factors for Violence

• Exposure to abuse: 63% of children exposed to domestic violence don’t do well. Violence is related to emotional development (hypersensitivity to anger, difficulties recognizing emotions or complex social roles, less accurate attention to social cues, less ability to generate competent solutions to interpersonal problems), cognitive problems (lower IQ, poor memory and concentration) and children who end up blaming themselves for the violence.

Page 26: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Risk Factors for Violence

• Peer relationships: One of the most significant risk factors for violence is association with peers whose norms, values and practices are more permissive of criminal behavior. Alternatively, attachment to conventional others, involvement in conventional activities, and belief in the central value system of society hinders juveniles from engaging in delinquent behavior.

Page 27: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Subtypes of CD

• Childhood onset– Presence of 1 criteria before age 10– Typically boys exhibiting high levels of aggression, may also be

diagnosed as ADHD. – Problems tend to persist to adulthood (33% APD)

• Adolescent onset– No criteria met before age 10– Less aggressive, more normal relationships– Most behaviors shown in conjunction with peers (e.g. gang

members)– Less ADHD. Equal gender distribution.– Much better prognosis

Page 28: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Limited Prosocial

• These youth are less likely to show empathy to others in distress, although they are capable of cognitively recognizing distress in others (unlike some autism).

• They are less sensitive to punishment and tend to be thrill-seeking and uninhibited.

• These youth are more likely to show both “instrumental” and “reactive” aggression.

Page 29: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Reactive Aggression

• Reactive aggression is characterized by impulsive defensive responses to perceived provocation. Over-reaction to minor threats is also seen.

• Such children may selectively attend to negative social cues, fail to consider alternative explanations for behavior, fail to consider alternative responses, and fail to consider the consequences.

• Most reactive aggression is associated with anxiety and depression.

Page 30: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Treatment of Reactive Aggression

• These youth generally are poorly socialized and have difficulty with emotional modulation:– Deal with hostile-attributional biases and

hypervigilance to hostility– Promote self-control mechanisms– Work with managing intense anger– Treat depression and anxiety

Page 31: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Instrumental Aggression

• In instrumental, or predatory, aggression, violence is used as a means to an end. These youth often show emotional detachment rather than emotional dysregulation.

• They do not focus on the negative effects of their behavior on others and resistant to punishment.

• Instrumental aggression in pre-adolescence predicts delinquency, violence, disruptive behavior during mid-adolescence, and criminal behavior with psychopathy in adults.

• Instrumental aggression is very difficult to treat.

Page 32: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Violence and Mental Illness

• Very few mentally ill are violent, but studies have demonstrated a small but increased risk of violence for the mentally ill - notably, substance abuse, cluster B personality disorders, psychotic disorders.

• Characteristics that are associated with violence:– Impulse control– Affect regulation– Narcissism– Paranoid personality style

Page 33: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Violence and Mental Illness

• The most seriously violent 5% of psychiatric clients account for half the violence.

• Violent and criminal acts attributable to mental illness account for a very small proportion of overall violence. Gender and age are more powerful predictors. The mentally ill are more likely to be victims than perpetrators - 11x higher than non-mentally ill. Their families are more likely to be the targets than unrelated people in the community.

Page 34: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Schizophrenia – Actuarial Risk Factors

• Past history of violence (forensic release - 50x risk of homicide)

• Substance abuse – Risk of homicide is 10x general population– Male schizophrenic AODA 17x– Female schizophrenic AODA 80x

• Non-adherence with treatment• Comorbid antisocial personality• Homelessness - 40x violent, 60x attempted murder,

25x murder

Page 35: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Schizophrenia – Actuarial Risk Factors

• Paranoid cognitive style• Hostility and irritability• Command hallucinations in some clients• Delusions - persecutory, systematized, focused

on an individual• The first year after diagnosis

Page 36: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Most Recent StudyKeers et al. Am J Psych March 2014

• In a longitudinal prospective study of 967 British prisoners incarcerated for a violent offense, it was found that schizophrenia and delusional disorder were not associated with violence after release, unless the patients were untreated. In the untreated group, it appears that violence was associated with the emergence of persecutory delusions.

Page 37: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Bipolar Disorder

• 25x general population, 49% lifetime prevalence• Impulsivity is prominent, even when clients are

asymptomatic.• Clients are often unpredictable: gregarious one

moment, hostile the next.• The delusional grandiosity that is often seen in mass

murderers implies bipolar mania more than schizophrenia. (Flagrant paranoia may likewise be more the result of a delusional depression than schizophrenia.)

Page 38: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Substance Abuse• 12-16x general population• These disorders have the highest correlates to violence,

more than all other disorders combined• Impulse control and affect regulation are both impaired by

these disorders.• Alcohol is involved in most murders. Drinking more than 5

drinks on any occasion increases the likelihood of violence, either as a perpetrator or victim.

• Alcohol is present in >50% of domestic violence, violent crimes, sexual assault, child abuse and neglect.

Page 39: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Personality Disorders

• Cluster B (borderline, narcissistic, histrionic, antisocial) are the highest risk because of impulsivity and affect dysregulation. Also, narcissistic injury may be an important factor.

• Clients with antisocial personality disorder will use violence to intimidate and control other people.

• About 75% of prison inmates meet the criteria of antisocial personality disorder. Only 33% of these will be psychopaths. They will have the highest number of criminal charges per year, the most violent crime, be responsible for the most violence in the prisons, and be most likely to recidivate.

Page 40: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Boundaries and Personality Disorders• Individuals with personality disorders will try various

ways to manipulate the therapist into giving them what they want. Some therapists may be more susceptible to trying to nurture a client who appears needy, leading to boundary violations.

Page 41: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Treatment

• Results for all forms of treatment for APD are generally dismal. Clients are not usually interested in treatment. Their dishonesty, sensitivity to power issues, and constant manipulating make them poor candidates for therapy.

• There is no evidence for the efficacy of any medications.

• Other treatments such as milieu, empathy, self-esteem training, or anger management, are problematic or have not shown any consistent benefit.

Page 42: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Treatment

• Treatment for borderline personality disorder is structured psychotherapy.

• No treatments have been carefully studied for narcissism or histrionic personality.

Page 43: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Organic Brain Disease

• 70% of brain injury clients have aggression and irritability as symptoms.

• Frontal Lobe Syndrome• Brief, unplanned, unsustained, ineffectual

• These aggressions are triggered by minor episodes, no clear aims or goals, explosive, remorse, long episodes of quiet.

• Epilepsy is rarely a cause of planned aggression.

Page 44: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Dementia

• Dementia invariably involves behavioral disturbances. These may be categorized as non-aggressive verbal (complaining, negativism), non-aggressive non-verbal (pacing, disrobing), aggressive verbal (threats, cursing) or aggressive non-verbal (spitting, kicking, hitting.) The most common disturbances are apathy (36%), depression (32%), and aggression (30%.)

Page 45: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Dementia• The evidence for non-pharmacologic and

pharmacologic interventions is weak. Historically, antipsychotics have been recommended, but side effects limit their long-term use. Evidence is poor for anticonvulsants or antidepressants. Cholinesterase inhibitors produce conflicting results. Various behavior therapies and environmental modifications are promising, but difficult to implement by families or in most care settings

Page 46: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Protecting Yourself

• Be alert at work, as when you are safely driving a car• Get hands on training from an expert. Practice

screaming fire or 911• Anticipate how you will react• Freeze• Flight• Fight• Fright• Faint• Psychytachia, tunnel vision/auditory exclusion

Page 47: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Responding to Verbal Aggression

• Hot Threats• The goal is to talk down the client. Make sure escape route is

available, and client can hear and understand you. Overdose with agreement. Don’t argue. Remember body buffer zones. Divide attention by giving choices. Denial is a serious impediment.

• Cold Threats• If you feel threatened, it’s a threat. Clients can intimidate by

praise or threats. Share your feelings with the team. Meet with the client and tell them how you feel, confront delusions, and go to the police if appropriate. Ignoring threats invites escalation.

Page 48: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Staying Safe

• Violence due to emotional arousal (anger) is the most common kind in mental health settings. It is easy to recognize anger, and verbal threats are red flags to prepare for violence. You must de-escalate the situation or leave.

• When you get up to leave, tell the client what you are doing so it will not be misinterpreted. Don’t block the door.

Page 49: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Our Problematic Reactions

• Denial– Common defense mechanism in response to fear,

even more common in mental health professionals. (We usually turn down our sense of alarm in order to do our jobs.)

• Countertransference– Issues that are not well-integrated and are

aroused by the client’s behavior. The clinician may act provocatively toward the client, over-control, or ignore the client’s threats.

Page 50: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Managing a CrisisMMHI Options Continuum

• Anxiety: client is pacing, ignoring others or giving them inappropriate attention– Staff response:• Open, supportive stance at angle to client (feet apart,

knees slightly bent, open hands at waist length)• Appropriate personal space with escape route (4-6 feet,

more for paranoid, be careful of geriatric client)• Listen and paraphrase empathetically and calmly• Avoid confrontational eye contact• Find out how you can help

Page 51: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Managing a CrisisMMHI Options Continuum

• Defensive Stage: client begins to act irrationally, challenging authority, intimidating, threatening• Staff response (at least two staff is necessary)

• Ready supportive stance (hands open at chest height)• Appropriate distance with escape route (10 feet, 21 feet if client has a

weapon)• Set clear, enforceable limits• Remain professional - don’t get provoked• Make sure there is no audience and allow client to vent• Restate limits when client can listen• Present positive options first• If no movement, or client shows pre-attack behavior, disengage to

develop a plan.

Page 52: The Dangerous Patient David Mays, MD, PhD dvmays@wisc.edu

Managing a CrisisMMHI Options Continuum

• Aggressive Stage: client loses control and becomes violent• Immediate cues to aggression

• Posture• Manner• Appearance• Voice• Verbal abuse or threats• Impaired cognition• Approach/avoidance• “gut” reaction