the 120 year diet

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120 Year Diet

Intermittent Fasting Nutrient Dense Vital and essential nutritional

cofactors

120 Year Diet

Dr. Walford 1950’s pioneer Under-nutrition without malnutrition Restrict calories 40% (of 2000 cal)

Today

Our current caloric intake has exploded

2,640 cal /day

Calories To Pounds

Varies 3,500

Basic Of Calorie Restriction

Vitamins Minerals Phytonutrients **Notice I didn’t mention cow

sandwhich

P

Range

40-70% Different methods My prefernces

Beneficial Mechanisms

CV effects Decreases HR, BP, LDL, triglycerides

Insulin Improved sensitivity Normalizes glucose levels

Beneficial Mechanisms

Increased protein synthesis Eliminates abnormal Chaperone molecules▪ Synthesis & maintenance of essential

proteins

Beneficial Mechanisms

Cell death (apoptosis) Modulates this process

Improves DNA repair and maintenance Benefits DNA transcription

Beneficial Mechanisms

Reduces oxidative stress Decreases qualitative & quantitative

levels Free radical = wrecking ball loose in your

body

Beneficial Mechanisms

Reduction in body fat mass Decrease visceral fat mass Increase muscle mass

Beneficial Mechanisms

Boosts hormone secretion Improves age related decline:▪ DHEA▪ Growth hormone

Beneficial Mechanisms

Improved brain function Memory Mood Cognition

Beneficial Mechanisms

Enhanced engagement in activity Growth factor stimulation

BDNF

Beneficial Mechanisms

WEIGHT LOSS

Calorie Restriction Mimetics

Simulate calorie restriction effects Examples:

Metformin Resveratrol Carnosine Avocado ALA Acetyl-L-Carnitine

Longevity

120 year diet What is the threshold ?125 or

beyond Epigenetics Nutrigenomics

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