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KHUPO 13 TH ANNUAL INTERNATIONAL PROTEOMICS CONFERENCE Integrated Proteomics: ProteogenomicsMarch 28 -29, 2013 Cultural Center, Seoul National University, Seoul, Korea THE KOREAN HUMAN PROTEOME ORGANIZATION (KHUPO) 3 rd CIRCULAR, Mar. 19 th , 2013 www.khupo.org/meeting

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Page 1: TH ANNUAL INTERNATIONAL PROTEOMICS CONFERENCEkhupo.org/meeting/data/file/season13/Circular/3rd_Circular_20130319.pdfand participants from the abroad and domestic in the 13th Annual

KHUPO 13T H

ANNUAL INTERNATIONAL

PROTEOMICS CONFERENCE

「Integrated Proteomics: Proteogenomics」

March 28 -29, 2013

Cultural Center, Seoul National University, Seoul, Korea

THE KOREAN HUMAN PROTEOME ORGANIZATION (KHUPO)

3rd CIRCULAR, Mar. 19th, 2013

www.khupo.org/meeting

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2 KHUPO 13th Annual International Proteomics Conference

CONTENTS

Invitation ................................................................................................... 3

General Information ................................................................................. 4

Program ................................................................................................... 6

Plenary Lecturers ................................................................................... 7

Symposia ................................................................................................ 8

Corporate Workshop ............................................................................ 11

Special Workshop ................................................................................ 12

Exhibition .............................................................................................. 13

Sponsors of KHUPO 2013 .................................................................... 14

Conference Venue ................................................................................ 16

Transportation ...................................................................................... 17

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INVITATION

On behalf of the Organizing Committee of the Korean Human Proteome

Organization (KHUPO), I would like to cordially invite all the speakers

and participants from the abroad and domestic in the 13th Annual

International Conference of KHUPO, which will be held on March 28~29,

2013 at the Cultural Center of Seoul National University, Seoul, Korea.

This 13th Annual Meeting of KHUPO focuses on the theme, “Integrated

Proteomics: Proteogenomics” For this meeting, four plenary lectures and

numerous distinguished scientists in the field were invited. I am very

much confident that this meeting will provide an excellent opportunity to

introduce and share the cutting edge results of proteomics research. In

addition it will also help us jump on more steps towards for the

development of proteomics core technologies and collaboration among the

scientists in Korea and rest of the world.

As proteomics is staged at the rapid growth phase with respect to

technology, training and infrastructure in the world, Korean scientists will

continually contribute to explore and elucidate all human proteome

researches. I hope the efforts and activities of KHUPO or proteomics

community will serve as the basis for the functional characterization of all

proteins and their variants relevant to human biology and disease.

Finally, I hope that 13th Annual Conference of KHUPO serves as a major

scientific forum for the high-quality research of proteome scientists,

linking between Korea and the rest of the world.

With best wishes,

Chan-Wha Kim, Ph.D

President, The Korean Human Proteome Organization

Professor, College of Life Sciences and Biotechnology, Korea University

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GENERAL INFORMATION

� Date: March 28 (Thursday) – 29 (Friday), 2013

� Venue: Cultural Center, Seoul National University, Seoul, KOREA

� Theme: “Integrated Proteomics: Proteogenomics”

� Official Language: English

� Organizer: The Korean Human Proteome Organization (KHUPO)

Con

The Korean Human Proteome Organization (KHUPO)

Rm#422, Industry-University Building, Yonsei University

134 Shinchon-dong, Sudeamoon-gu, Seoul, 120-749, Korea

Tel: 82-2-393-8328, Fax: 82-2-393-6589, E-mail: [email protected]

URL: http://www.khupo.org/meeting

Conference Information

Contact Address

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GENERAL INFORMATION

Organizing Committee

President Chan-Wha Kim (Korea University)

Vice President Dae Kyoung Kim (Chung-Ang University)

Bonghee Lee (Gachon University)

Je Kyung Seong (Seoul National University)

Hun Choi (SCINCO Co. Ltd)

Secretary General Je-Yoel Cho (Seoul National University)

Secretary of Academic Affair Youngsoo Kim (Seoul National University)

Cheolju Lee (Korea Institute of Science and Technology)

Sang Won Kang (Ewha Womans University)

Secretary of Financial Affair Byoung Chul Park (Korea Research Institute of Bioscience &

Biotechnology)

Secretary of Editorial Affair Kwang Pyo Kim (Konkuk University)

Secretary of Planning Jin Han (Inje University)

Secretary of Int. Cooperation Jong-Won Yun (Daegu University)

Secretary of Membership Daehee Hwang (Pohang University of Science and Technology)

Secretary of Advertising Kang-Sik Park (Kyung Hee University)

Secretary of Education Hookeun Lee (Gachon University)

Jin Young Kim (Korea Basic Science Institute)

Secretary of Public Relation Jae-Pil Jeon (Korea National Institute of Health)

Eun-young Lim (Agilent Technologies Korea Ltd.)

Chair, Committee for Election Affair Kwon-Soo Ha (Kangwon National University)

Chair, Committee for Fund-Raising Affair Young Mok Park (Korea Basic Science Institute)

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PROGRAM AT A GLANCE

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PLENARY LECTURERS

Plenary Lecture 1

Mar. 28(Thu) 09:00-09:40

Chair: Chan-Wha Kim (Korea University, Korea)

A draft map of the human proteome and integrating multi-Omics datasets for human genome annotation

Akhilesh Pandey (Johns Hopkins University, USA)

Plenary Lecture 2

Mar. 28(Thu) 16:00-16:40

Chair: Hun-Taeg Chung (University of Ulsan, Korea)

Shifting Proteomics from a Hypothesis Generating Workflow to a Hypothesis Testing Workflow

Michael MacCoss (University of Washington, USA)

Plenary Lecture 3

Mar. 29(Fri) 09:00-09:40

Chair: Ho Jeong KWON (Yonsei University, Korea)

New Concepts in Understanding Metastasis: The Amoeboid Tumor Phenotype and its Relationship to Cancer Metabolism

Michael Freeman (Cedars-Sinai Medical Center, USA)

Plenary Lecture 4 Mar. 29(Fri) 16:00-16:40

Chair: Young-Ki Paik (Yonsei University, Korea)

Genome-wide proteomics: The Specification of the Parts Lists of chromosome 17 as part of the chromosome-centric Human Proteome Project (C-HPP)

William Hancock (Northeastern University, USA)

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SYMPOSIA

Symposium 1 Disease Biomarker Mar 28 (Thursday) 09:40-10:50

Chair: Eun Gyeong Yang (Korea Institute of Science and Technology, Korea)

(SY-1-1) 09:40-10:10 A ProteoGenomic Cancer Atlas – A NCI Program

Henry Rodriguez (National Cancer Institute, USA)

(SY-1-2)

10:10-10:30

Proteomics and Metabonomics Researches of Major Depression:

Identification of Potential Biomarkers

Peng Xie (Chongqing Medical University, China)

(SY-1-3) 10:30-10:50

A strategy for SRM-based verification of biomarker candidates discovered

by iTRAQ in cancer tissue samples

Takeshi Tomonaga (National Institute of Biomedical Innovation, Japan)

Symposium 2 Proteogenomics Mar 28 (Thursday) 11:10-12:20

Chair: Kim Hyung-Lae (Ewha Womans University, Korea)

(SY-2-1) 11:10-11:40 Re-annotation of the genome of Thermoanaerobacter tengcongensis by the

in depth proteome analysis

Quanhui Wang (Beijing Institute of Genomics, China)

(SY-2-2) 11:40-12:00 Rapid design of SRM peptide transitions via multiplexed SRM-triggered

MS/MS methods

Eugene C. Yi (Seoul National University, Korea)

(SY-2-3)

12:00-12:20

Developing Proteome-to-Genome Mapping Technologies for Effective

Discovery of Biomolecular Signature

Sang-Won Lee (Korea University, Korea)

Symposium 3 BioChip Mar 28 (Thursday) 14:50-16:00

Chair: Jaebum Choo (Hanyang University, Korea)

(SY-3-1) 14:50-15:15

High-Throughput Analysis of Protein-Protein Interactions Using Droplet-

based Microfluidics

Soo-Ik Chang (Chungbuk National University, Korea)

(SY-3-2) 15:15-15:40 Identification of human-microbe protein interactions using E. coli proteome

microarray

Chien-Sheng Chen (National Central University, Taiwan)

(SY-3-3) 15:40-16:00 A Human Breathing Lung-on-a-Chip for Nanotoxicology and Drug Screening

Applications

Dongeun Huh (Seoul National University, Korea)

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Symposium 4 Antibody Proteomics Mar 28 (Thursday) 17:00-18:10

Chair: Kim Sun Yeou (Gachon University, Korea)

(SY-4-1) 17:00-17:25 Antibody against basigin restores anti-cancer drug sensitivity of breast

cancer

Kristine M. Kim (Kangwon National University, Korea)

(SY-4-2) 17:25-17:50 Antibody-based proteomics for the functional study of the ion channels

Kang–Sik Park (Kyung Hee University, Korea)

(SY-4-3) 17:50-18:10 Quantitative analysis of protein lysine acetylation in gastric cancer using

antibody-based Super SILAC approach

Je-Hyun Baek (Seoul National University, Korea)

[This Session is supported by Converging Research Headquarter for FMI]

Symposium 5 PTM

Mar 29 (Friday) 09:40-10:50

Chair: Seung Il Kim (Korea Basic Science Institute, Korea)

(SY-5-1) 09:40-10:05 Glycoproteomics for cancer biomarker discovery

Jong Shin Yoo (Korea Basic Science Institute, Korea)

(SY-5-2) 10:05-10:30 Mitochondrial deacetylase Sirt3, Carcinogenesis, and Metabolisms

Hyun-Seok Kim (Ewha Womans University, Korea)

(SY-5-3) 10:30-10:50 Glycan-Targeting Serial Affinity Chromatography in Proteomics

Wonryeon Cho (Wonkwang University, Korea)

[This Session is supporte

Symposium 6 Systems Biology Mar 29 (Friday) 11:10-12:20

Chair: Youngsoo Kim (Seoul National University, Korea)

(SY-6-1) 11:10-11:40 Drugs, Bugs and Immunity

Anthony Purcell (Monash University, Australia)

(SY-6-2) 11:40-12:00

Systems biology: Converting 'omics' into 'networks'

Kwang-Hyun Cho (Korea Advanced Institute of Science and Technology

(KAIST), Korea)

(SY-6-3) 12:00-12:20 Study of the Plant Defense and Immunity Signaling using Integrated OMICS

Approach

Yet-Ran Chen (Academia Sinica, Taiwan)

[This Session is supported by Molecular Inflammation Research Center for Aging Intervention]

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Symposium 7 Redoxomics Mar 29 (Friday) 14:50-16:00

Chair: Yun Soo Bae (Ewha Womans University, Korea)

(SY-7-1) 14:50-15:20 Pharmacoproteomics: Absolute quantification of protein interactions for drug

target identification

Tohru Natsume (Advanced Industrial Science & Technology, Japan)

(SY-7-2) 15:20-15:40 ROSics I: Proteomics of Cysteine Modifications in Redox Biology

Kong-Joo Lee (Ewha Womans University, Korea)

(SY-7-3) 15:40-16:00 Application of mass spectrometry in protein tyrosine nitration

Kwang Pyo Kim (Konkuk University, Korea)

[This session is supported by a program of Redoxomic Research of the Ministry of Education, Science and

Technology (MEST)]

Symposium 8 Human Proteome Project Mar 29 (Friday) 17:00-18:10

Chair: Young Mok Park (Korea Basic Science Institute, Korea)

(SY-8-1) 17:00-17:23 Chromosome 11-Centric Human Proteome Analysis of Human Brain

Hippocampus Tissue

Kyung-Hoon Kwon (Korea Basic Science Institute, Korea)

(SY-8-2) 17:23-17:46 Genome-wide mapping and functional characterization of the human

proteome

Hyoung-Joo Lee (Yonsei Proteome Research Center, Korea)

(SY-8-3) 17:46-18:10 Creating Human Brain Proteome Atlas - Hippocampus as the first model

Young Mok Park (Korea Basic Science Institute, Korea)

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CORPORATE WORKSHOP

Workshop 1 Agilent Technologies Korea Ltd.

Mar 28 (Thursday) 12:20-12:50

(CW-1) 12:20-12:50 Facilitating discovery and understanding of key biological pathways using Agilent integrative multi-omics analysis solution.

Jung, Hyun-Jin (Agilent Technologies Korea Ltd.)

Workshop 2 AB SCIEX Korea

Mar 28 (Thursday) 12:50-13:20

(CW-2) 12:50-13:20 MS/MSALL with SWATH™ Acquisition Comprehensive Quantification with Qualitative Confirmation using the TripleTOF™ 5600+ System

Byung-Hee Shin (AB SCIEX Korea)

Tracking viral infection using next generation mass spectrometry

Anthony W Purcell (Monash University, Australia)

Workshop 3 SCINCO Co. Ltd

Mar 29 (Friday) 12:20-12:50

(CW-3) 12:20-12:50 Advances in high resolution accurate/mass measurements in studying the quantification of post translational modifications.

Benjamin C. Orsburn (Thermo Scientific)

※ Lunch Box will be given to all of participants in corporate workshop 1 and 3.

※ Gift will be given to all of participants in corporate workshop 2.

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SPECIAL WORKSHOP

- Joint Workhop with Chungcheong Institute for Regional Program Evaluation (CIRPE) -

Workshop Multiomics approaches for the new drug development

March 28 (Thursday) 13:20-14:20

Chair: Kwang Pyo Kim (Konkuk University, Korea)

(SW-1) 13:20-13:30 Development of Biosimilar Therapeutic Antibodies Young Min Kim (Hanwha Chemical)

(SW-2) 13:30-13:40 GPR43, an Innovative Target for Inflammatory Diseases

Sunhong Kim (Korea Research Institute of Bioscience and Biotechnology)

(SW-3) 13:40-13:50 Clinical Development of Tanibirumab and Its Next Generation Therapeutics

Jin-San Yoo (PharmAbcine Inc.)

(SW-4) 13:50-14:00 LCMS based high throughput screening of natural products without fractionizatoins

Yongsoo Choi (Korea Institute of Science and Technology)

(SW-5) 14:00-14:10 Mechanisms of acquired resistance to targeted cancer therapies

Eugene C. Yi (Seoul National University)

(SW-6) 14:10-14:20 Application of imaging mass spectrometry for drugs and their metabolite

Kwang Pyo Kim (Konkuk University)

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EXHIBITION

1. Exhibition Session Information

Date : March 28 (Thursday) – 29 (Friday), 2013

Exhibition Time : March 28, 10:00-17:00 / March 29, 10:00-17:00

Place : Exhibition Hall (1F), Cultural Center, Seoul National University

2. Booth Map

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SPONSORS OF KHUPO 2013

Diamond Sponsors

Agilent Technologies www.agilent.co.kr

Gold Sponsors

SCINCO CO., LTD. www.scinco.com

Exhibitions

ASTA www.maldiplate.co.kr

AB SCIEX Korea

Bruker Biosciences Korea

www.absciex-korea.com

www.bruker.com

CHAYON Laboratories Inc. www.chayon.co.kr

Dong-il SHIMADZU Corp. www.shimadzu.co.kr

DRP Bio

Interface CO.,Ltd. www.interface.co.kr

KOMABIOTECH

MACROGEN

www.komabiotech.co.kr

www.macrogen.com

Nexbio. Co., Ltd. www.nexbio.co.kr

Seoulin BioScience Co.,Ltd. www.seoulin.co.kr

Taeshinbio Science www.taeshinbio.co.kr

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Sponsors and Advertising

Chungcheong Institute for Regional Program Evaluation

Chungnam Techno Park

Daho Korea

DIATECH Korea

Dong-A Pharm.

Hanil Sci-Med Co, Ltd

KBSI-Convergence Research Center for Mass Spectrometric Diagnosis

KDR

KOOKSOONDANG Brewery

Korea National Institute of Health

Korean BioInformation Center

Peptron, Inc.

Sartorius Korea Biotech Co., Ltd.

Waters Korea Limited

Yonsei Proteome Research Center

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CONFERENCE VENUE

Cultural Center, Seoul National University

Seoul National University Map

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TRANSPORTATION

▶ Way by Airplane (Incheon International Airport)

# 1

Take airport limousine bus No. 6003 to the Seoul University at 6A or 12B Exit (1st Floor) and get off at the

Seoul National University. The bus takes off from the airport every 12~20 minutes or so. Depending on traffic

conditions, the bus ride to the hotel will take 90 minutes.

Incheon International Airport bus/taxi stop map.

- Limousine Bus Cost (Adult) : KRW 9,000

-Bus Stop : Gimpo Int'l Airport - Songjeong Station - Balsan Station - 88 Gymnasium - Hotel Nostalgia - Deungchon Middle School(Hotel GreenWorld) - Gangseo-gu Councill - Daeil High School - Mok-dong Sageori - Mok-dong Station - Galsan Elementary School - Guro Industrial Tool Arcade - Guro Station - Guro-gu Office - Daerim Station - Lotte Dept. Store(Gwanak) - Sillim Station - Bongcheon Station - Seoul Nat'l Univ. Station - Gwanak-gu Office - Seoul Nat'I University

# 2

Take taxi at Incheon International Airport directly to Seoul National University.

Fares : approximately 70,000 won (Standard Taxi)

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▶ Way by Seoul Metro Subway

# Line No.2 (Green Line), Seoul National University Entrance Station (Exit No. 3)

After exiting exit no.3, walk towards the Gwanak-gu Office. There you will find the school shuttle bus and

also a regular bus that comes to SNU. The campus shuttles are free of charge. The operation and interval

of the buses differ during vacation time and semesters, but is usually in the range of every 5 to 20 minutes.

Buses number 5511 and 5513 circulate the campus counter-clockwise, from the main entrance towards

the Administration Building next to Cultural Center.