syllabus 2 year of the engineering cycle - psl

february2019version 1

ChimieParisTech

SYLLABUS

2ndYEAROFTHEENGINEERINGCYCLE


The first semester of the second year presents the different fields of applications of chemistry:

materials,polymers,biochemistry,energy)

Thesecondsemesteroffersachoiceoffiveoptionsinthesecondsemester:analyticalandbiological

chemistry (in English), processes, materials (in English), molecular chemistry, biotechnologies (in

exchangewithESPCI).Thelessonsbecomemorein-depthineachoption.

Themanagementcoursesfocusonlifeandworkinthecompany.

Studentscarryoutaninnovationprojectinagroupthroughouttheyear.Thisprojectissubmittedby

aclient.Theprojectisdividedintothreephases:inspiration,development,realization.Duringthefirst

semester theywrite specifications and study the state of the art and literature (scientific, patent,

internet).Theydevelopaninnovativeproposalthattheyhavevalidatedbytheirsteeringcommittee.

Duringthesecondsemestertheymakeaprototypeprovingthefeasibilityoftheirproposal.

Studentsdoafive-monthinternshipatthemasterlevel.

Semestre3:

Materialsandprocesses(6ECTS)

• Chemicalreactionengineeringandprocesssafety

• Metallicmaterials

• PracticalworkinMetallurgy

• Experimentaltraininginchemicalengineering

Molecularandbiologicalchemistry(6ECTS)

• Biochemistry

• Polymerchemistry

• PracticalcoursesinPolymerSciences

• PracticalcoursesinBiochemistry

Physicalchemistry(6ECTS)

• ThermostaticsandMolecularModeling

• Analyticalphysico-chemistryforbioanaysisand

environment

• Innovationanddigital(6ECTS)

• Programmingproject

• Digitalengineer

• Groupinnovationprojects

Management:Humanresources(6ECTS)

• HumanResourcesManagement

• English

OptionalCourses

• AthensWeek

• Sport

• Foreignlanguages


Semestre4:

1optiontobechosen 6ECTS 6ECTS

Analyticalandbiological

chemistry

• Modernanalyticalchemistryforbiotechnology

andclinicaldiagnostics

• Chemistryprobesforbioimaging

• Basicconceptsofcellularbiology

• PracticalBiotechnology

• BioinorganicChemistry

• Molecularmodeling

• Organometallicchemistry

• EnergiesConferencesMolecularchemistry

• Heteroelementsandappliedcatalysis

• AsymmetricSynthesisandRetrosynthesis

• Experimentaltraininginmolecularchemistry

Materials

• PhysicsIII:ElectronicPropertiesofSolids

• Surfacepropertiesandenduranceofmaterials

• Inorganicmaterialselaboration

• Practicalworkinmaterialsscience

• Corrosion

• Inorganicchemistry:from

moleculestomaterials

• Modeling

• EnergiesConferences

Processes

• Processsimulation

• Optimizationandprocesscontrol

• Flowchemistry

• Experimentaltrainingforflowchemistry

Biotechnologies OptionoccurringattheESPCIengineeringschool

Management:Humanresources(6ECTS)

• HumanResourcesManagement

• English

Professionalproject(12ECTS)

• Internship2A(5months)

OptionalCourses

• PSLWeek

• Sport

• Foreignlanguages


SEMESTER3

2A

S3MH23ES.GC

ChemicalreactionengineeringandprocesssafetyKeywords:Chemicalreactionengineering,Idealreactors,Riskanalysismethods(HAZOP,

Eventtree,failuretree,Whatif)

Responsible:MichaelTatoulian,C.Guyon,M.Zhang,S.Ognier,F.Rousseau,W.Benaissa(Solvay),MickaelArnold(Sanofi),Vincent

Piepiora(Total–Energo)

[email protected]

ECTS: Course Tutorials Practical

work

Mentoring Evaluationmethod:writtenexam

22.5h 3h h

Courseoutline:

Theconcept"chemicalreactionengineering"representstheapproachrequiredbytheengineertoimplement

thetransformationofselectedreagentsintodesiredproducts.Asaresult,thereactorcombinesthechemist's

reactionmechanisms,whichdefinetheorderof thestepsnecessarytoobtainthedesiredproducts,withthe

transfermechanisms(material,heatandquantityofmovement)inordertoallowthereactionmechanismstobe

establishedwithcontrolledkinetics,preciseselectivityanddefinedreproducibility.Theoptimalimplementation

of chemical transformation requires knowing how to choose the most suitable reactor (batch reactors,

continuous stirred tank reactor, plug flow reactor, continuous, discontinuous operation), and to define the

operatingconditions.Firstwewillpresentthespecificitiesofthedifferentidealreactorsandtheircharacteristic

equationsallowingtoaccesstheperformancesoftheprocess(conversion,selectivity).Thenwewillapproach

situationsclosertorealitybytakingintoaccountthethermicityofthereactionsbycarryingoutheatbalanceson

thesesamereactors.

Finally, studentswill have toanalyse the safetyof chemicalprocessesbyusingdifferentprocess-specific risk

analysismethods(HAZOP,What-if,Faulttrees,eventtrees...).

Thesecourseswillbecomplementedbypresentationsbyindustrialistsillustratingtheissuesofchemicalprocess

developmentinbatchreactors(Sanofi),processinstrumentation(Total)andprocesssafetyandthermalrunaway

issues(Solvay,INERIS).

Learningobjectives:

Attheendofthecourse,studentsmustbeableto:

Beabletounderstandthespecificitiesoflargeindustrialreactors

Beabletowriteamaterialbalanceandaheatbalanceinthecaseofidealreactors

Beabletodimensionareactorandcalculateitsperformance

Beabletoensuretheoperationalsafetyofaprocessbyusingriskanalysismethods

Prerequisites:

generalchemistry-Kinetic

Teachinglanguage:french

Documents,website:handoutshttps://coursenligne.chimie-paristech.fr


2A

S3MH23ES.MM Metallicmaterials

Keywords:Metallurgy,alloys,phasediagrams

Responsible:FrédéricPRIMAProfesseur

[email protected]


work

Mentoring Evaluationmethod:writtenexamination

21h 3h 14h

Courseoutline:

Theobjectiveofthiscourseistoprovidestudentswithafoundationinstructuralmetallurgy.

Itaddressesvariousrelatedaspects:

Microstructuresofmetalalloys:structuralaspects(defects),chemicalaspects(diffusion),thermodynamicaspects

Thestudyofstructure/propertyrelationships(introduction)

Tothesolidificationofalloys(thegenesisofthesemicrostructures)

Phasediagrams(binaryandternary)

Phasetransformations:kinetic,thermodynamicandcrystallographicaspects

Industrialprocessesforthemanufactureofmetallicmaterials(thermomechanicaltreatments)

The course is completed by 2 days of practical work on metallurgy illustrating the relationship between

microstructureandmechanicalproperties(hardeningandtensilestudies)

Learningobjectives:

Attheendofthiscourse,thestudentmastersthedifferentconceptsofmetallurgy.

Heknowshowtomakethelinkbetweenthermodynamicaspectsandmicrostructuresofmetallicmaterials

Itunderstandstherelationshipbetweenthemicroscopicaspectsofamaterialanditsmacroscopicpropertiesin

termsofmechanicalbehaviour.

Hecandevelopasynthesisstrategyinrelationtotheexpectedpropertiesofanalloy.

Prerequisites:

bachelorlevelinthermodynamicsandsolidstatechemistry


Documents,website:


2A

S3MH23FE.GC

Experimentaltraininginchemicalengineering(2ndyear)Keywords:Chemicalengineering,reactors,unitoperations,processes,simulation,Hysys,

Comsol

Responsible:FredericRousseauAssociateProfessor

[email protected]


work

Mentoring Evaluationmethod:writtenreports(worksynthesis

andskillsassessment)

0h 0h 22.5h

Courseoutline:

Theobjectiveof this Teaching is toput intopractice thenotionsof chemical engineering that studentshave

acquiredinthefirstyearandduringthefirstsemesterofthe2A.Students,ingroupsofthree,pilotandstudy

experimentalpilotinstallations(tubularorstirredtankreactors,calorimetertypeDSC).Thisallowsstudentsto

influence the properties and particularities of the main reactors used in chemistry. They also discover the

principleofacquiringkineticmeasurementsofchemicalreactionsusingcalorimetry.Finally,theybuildindustrial

processsimulationsusingASPENHYSYSandCOMSOLsoftwareinsteadystatemode.Inthisway,studentslearn

goodsimulationpractices inchemicalengineeringandacquiretheconceptsofdegreesoffreedom.Theyalso

learntoremaincriticaloftheresultsobtainedbythesetools.

Learningobjectives:

Attheendoftheteaching,thestudentwillbefamiliarwiththespecificitiesandpropertiesofchemicalreactors

usedinresearchandindustry.ItwillbesuitablefortheimplementationofkineticmeasurementsfromaDSCtype

calorimeter.Itwillalsobeable,dependingonthecomplexityoftheproblem,toselectthemostrelevantsoftware

tostudyasinglereactororacompleteprocessinsteadystate.

Thestudentwillmasteraknow-howconsistingintheconstructionandoptimizationofastationarysimulation

includingareactorandvariousoperationsofpressurebuild-up,heating,separation,purification...Hewillbeable

toremaincriticaltowardsthehypothesesformulatedandtheresultsobtainedfromsimulationtools.

Prerequisites:

notionsoftransfersofquantityofmovement,matterandenergy/unitoperations/reactorcalculations


Documents,website:handoutsandpdfdocuments


2A

S3MH23ES.BIO FundamentalsofBiochemistry

Keywords:biochemistry,protein,enzymology,nucleicacid,carbohydrate,lipid

Responsible:OlivierPlouxProfesseur

[email protected]


work

Mentoring Evaluationmethod:Writtenexamof1:30h(no

documents,noelectroniccalculator)

16.5h 6h 0h

Courseoutline:

Thiscoursedescribesthefundamentalmolecularprocessesthattakeplaceinlivingcells.Weshalldescribethe

structure and function of themajor biologicalmacromolecules. The flux of information in the cells and the

evolutionprincipleswillbediscussed.Non-covalentinteractions;Proteins:structureandfunction;Enzymology:

fundamentalenzymepropertiesandapplications;Nucleicacids:structureandfunction;replication;transcription,

translation;Carbohydrates:structure,reactivity,andfunction;Lipidsandbiologicalmembranes.

Learningobjectives:

Afterattendingthiscourse,thestudentshouldknowthemainnon-covalentinteractionsthatareimportantin

lifesciences:electrostatic,VanderWaals,hydrogenbonds,hydrophobicinteractions.

Thestudentshouldbeabletodescribetheprimary,secondary,tertiaryandquaternarystructureofproteinsas

wellasdefiningthenativestructureanditsmainproperties.

ThestudentshouldbeabletodescribeMichaelis-Mentenenzymekinetics,explainhowenzymeworks(catalysis

type,reactionmechanismoftypicalproteases)andtounderstandtheeffectofreversiblecompetitiveinhibitors

onenzymesandofcovalentinhibitors.

Thestudentshouldbeabletodescribethestructureofnucleicacids(DNAandRNA)andthemechanismofthe

flux of information transfer in the cell (replication, transcription, translation), and the synthesis of deoxy-

oligonucleotides,aPCRexperiment,andtheDNAsequencingbytheSangermethod.

Thestudentshouldbeabletodescribethestructureofhexosesandketoses(fromthreecarbonstosixcarbons;

Fischer projection, Haworth representation and chair conformation), to know their reactivity (cyclization,

mutarotation,isomerization)

Thestudentshouldbeabletodescribethestructureofsimplelipidsandoftheirmaincomponents(fattyacids,

triglycerides,phospholipids)andtodescribethestructureofthebilayermembraneandthemainfunctionsofthe

biologicalmembranes.

Prerequisites:

Structural chemistry: atoms, molecules and covalent bonds; bond electronic polarization; mesomery; non-

covalentinteractionincl


Documents,website:pdfdocumentoftheslidepresentation


2A

S3MH23ES.POL PolymerChemistry

Keywords:

Responsible:THOMASChristopheProfesseur

[email protected]


work

Mentoring Evaluationmethod:Basicprinciplesoforganic

chemistry

12h 10.5h 0h

Courseoutline:

Thiscourseintroducesthebasicsofthemajormethodsofpolymersynthesis.Thiscourseprovidesstudentswith

thefundamentaltoolsnecessarytounderstandthestructure/propertyrelationshipsofpolymers.Thiscoursealso

showsstudentshowthecontrolofpolymerizationreactionsbyajudiciouschoiceofinitiatororcatalystsystems

and experimental synthesis conditions can produce perfectly defined macromolecular structures and

architectures.

Learningobjectives:

Attheendofthecourse,thestudentwillbeabletousethemajorconceptsofpolymerchemistryandpropose

methodssuitableforthecharacterizationofpolymersinsolutionandinsolidstateandtocontrolthemforsome

ofthem(DSC,SEC,RMN,MALDI-ToF).

Prerequisites:


Documents,website:


2A

S3MH23FE.POL PraticalCoursesinPolymerSciences

Keywords:polymers,softmatter,radicalpolymerization,ROP,biodegradablepolymers

Responsible:CarineRobertMaîtredeConférences

[email protected]


work

Mentoring Evaluationmethod:Writingreportabouttheresults

oftheproject

0h 0h 22.5h

Courseoutline:

Practicalcoursesinpolymersciences.Oneprojectisstudiedbytwo-personteamforthreedaysfrompurification

ofstartingmaterialstocontroledsynthesisandstudyofphysico-chemicalpropertiesofashapedobject(NMR,

DSC,SEC).

Learningobjectives:

Thestudentwillbeabletocarryoutasynthesisofpolymerizationlinkedtothedesiredpropertiesofthematerial

(thermoplastic,thermoset,elastomer,hydrogel,biodegradablepolymer).

Prerequisites:

PolymerSciencesS3


Documents,website:handoutshttps://coursenligne.chimie-paristech.fr/course/view.php?id=295


2A

S3MH23FE.BIO PracticalcourseinBiochemistry

Keywords:Proteins,DNA,Extraction,analysis

Responsible:CorinneMARIE

[email protected]


work

Mentoring Evaluationmethod:Theratingisbasedonthe

evaluationofareportandtheassessmentofthe

student'sskills

22.5h 0h 0h

Courseoutline:

The modification of living organisms has become a major strategic challenge for the optimisation of many

industrialprocesses.Aspartofthisexperimentaltraining,wewishtointroducedifferenttechniquescommonly

usedtomodifyandanalyzetheDNAorproteinsofacell.Wealsoaimtoillustratetheknowledgecoveredduring

thelecturesofBiochemistry.

Learningobjectives:

Attheendofthetraining,thestudentwillbeabletoextractandanalyzetwomajorgroupsofbiomoleculessuch

asproteinsandDNAwhosestructuresandcharacteristicshavebeencoveredintheBiochemistrycourse.The

studentshouldalsoconductbibliographicresearchtodeterminethelimitsoftheproposedtechniquesand,if

necessary,proposealternativeprotocols,specifyingtheiradvantagesanddisadvantages.

Inadditiontotheacquisitionofnewtechniques,thestudentshouldsummarizetheexperimentalresultsobtained

bydiscussingthemandcomparingthemwithbibliographicdata.

Prerequisites:

Knowledgeof theDNAandproteinsstructuresandmajorcell compartments thatwerepresentedduring the

Biochemistrycourse


Documents,website:handoutsandslidepresentation


2A

S3MH23ES.TMM ThermostaticsandMolecularModeling

Keywords:molecularmodeling

Responsible:CarloAdamoProfesseur

[email protected]


work

Mentoring Evaluationmethod:Writtenexam

10.5h 7.5h 0h

Courseoutline:

Thismoduleaimstotraintheengineeringstudentinthemainmolecularmodellingmethods.

Themainconceptscoveredare:classicalmethods(mechanicalandmoleculardynamics)forthedescriptionof

matter(frommoleculetobiosystems)aswellastheircouplingwithab-initioorsemi-empiricalquantummethods,

thedescriptionofthechemicalenvironmentwithparticularattentiontosolvatingmethods,andtheexploration

ofsurfacesofpotentialenergy.

ThetrainingisbasedonalternatingcourseandTDsessions.DuringtheTDs,usingcalculationsoftware,students

canapplytheillustratedmethodsinclasstopredictthesolvationandreactivityofsimpleorganicsystems.

Learningobjectives:

Thestudentmustbeableto:

-knowthebasicsofmolecularmechanicsandmoleculardynamics

-choosethemostsuitablemethodtomodeltheenvironment(solvent)

-knowhowtodescribechemicalreactivity

Prerequisites:


Documents,website:handouts


2A

S3MH23ES.PCA Analyticalphysico-chemistryforbioanaysisandenvironment

Keywords:sampletreatment,separation,detection,traceorevenultra-traceanalysis

Responsible:VarenneAnneProfesseur

[email protected]


work

Mentoring Evaluationmethod:Multiplechoicequestions,

Writtenreportandoralpresentationoftheproject

24h 0h 0h

Courseoutline:

Theoretical courses cover themost importantmethodologies in all areas requiringmonitoring and analysis,

allowing access toquantitative informationand interaction in solutions. These areessentially separative and

electroanalytical methods, in classical or miniaturized form. The aspects of separation, sample processing,

coupling of separative methods with sensitive and specific detection methods (fluorescence, mass

spectrometry...)arethusaddressed.Inaddition,thetheme"qualitycontrol"ispresented,includingstandards,

traceabilityandlifecycleanalysis.Theengineerisincreasinglybeingaskedtocontrolthepurityandstabilityofa

product by traceable methods (analytical traceability of measurements, validation of a method, sampling,

calibration, statisticalmethods, reporting and archiving, regulation, proficiency testing), with a view to their

accreditation by the standards, which are now at an international level. In the context of sustainable

development,thelifecycleanalysis(orecobalance)ofproductsispresented.

Themodule consistsofprojectwork (6 to7 studentsperproject)with the supportof a theoretical teaching

supportavailableonlineandconferencesgivenbyspecialistsindifferentfields.Theobjectiveofthisprojectisto

find in the scientific literature methods (electrochemical, chromatographic and electrophoresis) to quantify

traces/ultratraces (synthetic impurities,pollutants,biomolecules forpharmaceuticalapplication...) incomplex

matrices,definedbytheproject.Thedifferentmethodsselectedwillbecomparedintermsofprecisionquality,

easeofanalysis,etc.......andachoicewillbemadeonthemostappropriatemethod.

Learningobjectives:

Theobjectiveofthismoduleistoobtainacompleteandcriticaloverviewofthedifferentmethodologiesfortrace

orultra-trace analysis in complexmatrices (biological or environmental). The studentmust find, analyse and

criticizetheexistingbibliographyintheproposedfield,thenusehisknowledgetoselectthemostappropriate

methodorevenbeaforceofproposaltoimagineanewmethodology.Allthestepsofananalyticalmethodare

studied(sampling,processing,separation,detection).

Prerequisites:

Concepts fromthecoursesofsolutionchemistry,separationmethods,electrochemistry,physico-chemistryat

theinterfacesof1A


Documents,website:englisharticles


2A

S3MH23FE.PI Programmingproject

Keywords:project,numerical,C

Responsible:FrédéricLabatMaîtredeConférences

[email protected]


work

Mentoring Evaluationmethod:Writtenreportandoral

presentation.

0h 0h 45h

Courseoutline:

This module aims to train the engineering student to solve a concrete scientific problem requiring the

developmentofacomputerapplication.Byworkinginpairs,italsoaimstolearntoworkinateamandtopresent

itsworkinaclearandconcisemanner,intheformofawrittenreportandanoraldefenseusingaslideshow.

Theproposedprojectsarechoseninvariousfieldssuchaschemistry,physics,biochemistry,computergraphics,

orcryptography.Theyaimtodevelopthefollowingskills:

-analysisofascientificsubjectandchoiceofresolutionmethod

-translationoftheproblemintocomputerlanguage

-programcodingandvalidation

-scientificanalysisoftheresultsobtained

Learningobjectives:


-analyseascientificsubjectandchoosethemethodofresolution

-translateascientificproblemintocomputerlanguage

-codeandvalidateaprogram

-scientificallyanalyzetheresultsobtained

Prerequisites:

Cprogramming:basicsandalgorithms


Documents,website:


2A

S3S4

MH23TC.PIG

MH24TC.PIGGroupinnovationprojectKeywords:

Responsible:PhilippeBarbouxProfesseur

[email protected]


work

Mentoring Evaluationmethod:report50%Oralpresentation

50%

h h h

Courseoutline:

Thepurposeof theseprojects is to learnprojectmanagementand teamwork through thedevelopmentof a

technological innovationproject.Atechnologicalproject isastudyaimedatdevelopingan idea initiatedbya

"customer",whichmustresultfromaninnovationprocessaimedatcreating"anewproduct,anewservice,a

newgood",addingthatanewprocessoranewrecipeclosertochemistrycanbeincluded.

ProjectprogressProjectsaredividedintofivephases

1)Researchoftopicsandorganizationoftheteamandproject

2)Studyofthestateoftheartandanalysisofresources(patents,publications,internet,customervisit,etc.)

3)Elaborationoftheprojectandproposalphasetothesteeringcommittee.Circusdiscussionanddefenceofthe

project.Possibleorderofequipment

4)Technicalimplementation,development

5)Restitution(video10minutesorreportwrites15pagesthenoraldefenseoftheproject.

Learningobjectives:

The objective of learning is to learn to develop interdisciplinary skills in the field of project management

(timetable,programming)andinthescientificandtechnicalfield(analysisofthestateoftheart,bibliography,

initiative,designanddevelopmentofaninnovativeproduct)

Prerequisites:

Teachinglanguage:

Documents,website:


2A

S4MH24TC.MRT

HumanressourcesmanagementandManagementKeywords:management,leadership,HRM,SPRandoccupationalhealth,diversity,labour

law

Responsible:PhilippeVernazobresMaîtredeconférences

[email protected]


work

Mentoring Evaluationmethod:writingaskillsassessment+

MCQ

24h 13h h

Courseoutline:

Thiscoursecoversthemainaspectsofhumanresourcesmanagementandmanagement,usefultoanengineer

forhisintegrationinaprofessionalcontextandtheperformanceofhisduties:

-BeingaManagerandworkingwithHR

-Recruitandberecruited

-Developingtalentsandteams

-Managingcareersandpromotingdiversity

-Motivateandbemotivated

-Developleadershipandinfluence

-Managetime,delegateandmakedecisions

-Beinginvolvedinwell-beingandhealthatwork:preventingpsychosocialrisks(PSR)andpromotingqualityof

lifeatwork(QWL)

-UnderstandingLabourLaw

Inadditiontothecourses,threehalf-dayworkshops- ingroupsof15/20students-areorganisedtoprepare

themtoapproachthelabourmarketandthesearchforinternships:WS1:Skillsassessment-WS2:Jobinterviews

-WS3:AssesmentCenters.

Finally,inordertoknowthemselfbetter,eachstudentisinvitedtotaketheMBTI,aquestionnairedesignedto

understandtheirpsychologicalpreferencesandpreferredwaysofworking,whichiswidelyusedincompanies.

Learningobjectives:

Attheendofthecourse,thestudentwillbeableto:

•Understandthechallengesandpracticesofmanagementandleadership,andimplementtheminthecontext

ofengineeringwork.

•Understand,analyzeandapplyHRprocessesasanengineer,andworkincollaborationwithHRprofessionals.

•UnderstandthechallengesandpracticesofRPSprevention,andimplementthemasanengineer,intheservice

ofhealthandQualityofLifeatWork(QWL).

•Applyforajoboraninternship(interviews,AssesmentCenter...)

•Understandtheoverallframeworkoflabourlaw.

•Analyzeanemploymentcontractandunderstanditslegalconsequences.

•Knowyourselfbetter,self-assessyourself,developyourskills(softskills):becomeawareofyourmanagerial

andleadershipresourcesanddevelopthem,throughtheproposedmechanisms:MBTI,skillsassessment....

Prerequisites:

Attendingandvalidationoftheschool's1styearmanagementcourses.Orequivalentforstudentsenteringthe

2dyearoftheschool.




2A

S3S4

MH23TC.ANG;

MH24TC.ANG;SCIENTIFICANDBUSINESSENGLISHKeywords:English,Scientific,Business,InterculturalSkills

Responsible:DariaMoreauChargéedemissionlanguesetmanagementcommercial

[email protected]


work

Mentoring Evaluationmethod:Validationof5skills(seeCECRL

grid)atleastatB2/C1level

0h 30h 0h

Courseoutline:

EnglishclassesaimtoimproveEnglishskillsandteachlinguisticautonomyinordertopreparestudentstouse

technicalandscientificEnglishinaninternationalandinterculturalprofessionalcontext.

Theclassestakeplaceinlevelgroupsestablishedatthebeginningoftheyearonthebasisofbothaplacement

testandoralevaluations.Forthemostadvancedstudents(bilingualorC2accordingtoCECRL)itispossibleto

replace the classroom courseswith researchwork supervised by a teacher from the Department. Low-level

studentsmayattendone-to-onetutoringsessions.

Theclassroomcoursesarecomplementedbyanadaptedandvaried"e-learning"(theYesmagapplicationwhich

aimstofacilitatereadingtextsintheiroriginalversions;multiplelinguisticactivitiesonMoodle;self-studyinthe

languagelab).

Englishcoursesaretomaster:

-debatesonanysubject(cultural,economic,technical,scientific,etc.),withoutpriortrainingorspecialtraining

inordertobepartofajointoratoryteam,

-discussionsonculturaltopicsspecifictoAnglo-Saxoncountriesaswellasonscientificarticles,

-presentationsofauthenticprojectscarriedoutaspartofcross-curricularcourses,

-thepracticeoforalandwrittencomprehensionskills,

-thesynthesisandcomparisonofauthentictechnicaldocuments,

-analysisofinternshipoffersinEnglish-speakingcountriesandsimulationsofjobinterviews,

-writingcoverletters,

-technicalandscientificvocabulary,

-writingreportsonawiderangeoftopics,

-TOEICpreparationexercises(aTOEICmockexamwilltakeplaceattheendofeachsemester).

Learningobjectives:

The studentwill increase his/her in-depth knowledge of grammar and thematic and scientific vocabulary by

communicatingflawlesslyinbothwrittenandoralbusinessEnglishinamulticulturalcompany/Thestudentwill

be able to quickly access sources of internship or employment opportunities, analyse and synthesize the

employer’sexpectationsandrespondinEnglishtotheofferofinterest/ThestudentwillwriteinEnglishacover

letterand/oravideoCVto the internshipofferofhis/herchoice, taking intoaccount thecultural rulesofan

English-speakingcountry/Thestudentwillbeopentocollaborativework/Thestudentwillhaveastrongculture

ofatleastoneEnglish-speakingcountry/Thestudentwillgivea15-minute-longpresentationwithoutnoteson

his/hertransversalproject(withorwithoutPowerPoint)/Thestudentwillparticipateinadebateonaneveryday

life,technicalorscientificsubject/Thestudentwillanswerfactualquestionsonagivensubject/Thestudentwill

synthesizeascientifictextoranaudio,identifyrelevantinformationandpresentittoanaudience/Thestudent

willunderstandthestructureoftheTOEICtestanddevelophis/herpersonalstrategytomaximizehis/herexam

score.

Prerequisites:B2

Teachinglanguage:English

Documents, website : audio and video documents, factual documents https://coursenligne.chimie-

paristech.fr/course/view.php?id=31


SEMESTER4

2A

S4MH24ES.ENE

EnergiesConferencesKeywords:Energytransition,renewableenergysources,nuclearenergy,hydrogen,

intermittency,electricitygrid

Responsible:GERARDCOTEProfesseur

[email protected]


work

Mentoring Evaluationmethod:Studentattendancemonitoring

andfinalmultiple-choicequestionnaire

15h 0h 0h

Courseoutline:

The ENERGIES course underlines the challenges to overcome tomake acceptable the energy transition and

providesacriticaloverviewofpresentandemergingavailableenergysystems

Learningobjectives:

Attheendofthecourse,thestudentwillhave

-understoodthechallengesoftheenergytransition

-acquiredanoverviewofthestrengthsandweaknessesofpresentandemergingavailableenergysystems

-understoodhowelectricitygridsworkandthedifficultiestointegrateintermittentrenewableenergies

Prerequisites:

Chemistryandphysicslevelbachelor


Documents,website:pdfdocumentshttps://coursenligne.chimie-paristech.fr/enrol/index.php?id=306


ANALYTICALandBIOLOGICALCHEMISTRY-ABCOPTION

2A

S4MH24OP.CBI

BioinorganicChemistryKeywords:MedicinalInorganicChemistry,BioorganometallicChemistry,Bioinorganic

Chemistry,InorganicChemicalBiology.

Responsible:GillesGasser

[email protected]


work

Mentoring Evaluationmethod:WrittenExam.

15h 0h 0h

Courseoutline:

Natureutilizesmetalionsandmetalcomplexestoundertakeseveralcrucialprocesses.Infact,ahumanbeing

requiresabout25elementstohaveahealthylife,halfofthembeingmetals!Thechemicalstudyofmetalsin

biologyisreferredasbioinorganicchemistry.Thisareaofresearchencompassesthestudyofmetallo-enzymes

(i.e.vitaminB12)orbiologicalprocessessuchas respiration. In thiscourse,ageneraloverviewof the roleof

metals in biology will be presented. It is also planned to outline to role that metal complexes can play to

understandbiologicalprocesses.

Learningobjectives:

The course will be divided into twomain sections. In the first section, the role of metal ions in a few key

metalloproteinsandbiologicalprocesseswillbeexplained.Thesecondsectionwill focusontheuseofmetal

complexestodetectspecificorganelles/biomolecules,oradiscussiontounderstand/modifybiologicalprocesses.

Alargeemphasiswillbeplacedonexperiments,whichhavebeencarriedoutinlivingcellsororganisms.

Prerequisites:

Thiscourserequiresbasicknowledgeofinorganicchemistryandbiochemistry.

Teachinglanguage:english

Documents,website:


2A

S4MH24OP.MOM MolecularModeling

Keywords:


[email protected]


work

Mentoring Evaluationmethod:Writtenreport

4.5h 0h 9h

Courseoutline:

This module aims to train the engineering student in quantum and classical modelling of complex systems

(molecules,solids,biomolecules)ofindustrialinterest.Themethodsusedtodescribespectroscopicproperties

(IR,Raman,UV-Vis,NMRandEPR)andchemicalreactivityareparticularlytargeted.

Particularinterestisgiventosimulationmethodscurrentlyusedintheindustrialandapplicationfield,andtheir

use is illustrated by courses and seminars given by two external speakers frompublic or private institutions

presentingtheiractivity,inordertostrengthenthelinkbetweenmodellingandthebusinessworld.

ThetrainingisbasedonalternatingcourseandTPsessions,whichallowstudentstoputintopracticethemethods

describedinclassusingsoftwareofacademicandindustrialinterest.

Learningobjectives:


-choosethemostsuitablemethodaccordingtothepropertiesandsystemtargeted

-interprettheresultsobtainedandtheirlimitations

-interactwithmodellingexperts

Prerequisites:




2A

S4MH24OP.COM OrganometallicChemistry

Keywords:


[email protected]


work

Mentoring Evaluationmethod:Writtenexamination

7.5h 7.5h 0h

Courseoutline:

Thiscoursedescribesthefundamentalreactionsoftransitionmetalcomplexesandsome(industriallyrelevant)

catalyticcycles.Thiscourseprovidesanintroductiontocatalysisasatoolforthedevelopmentofcleanandenergy

efficientsynthesisprocesses.

Learningobjectives:

The first objective of this course is to rationalize the reactivity of catalytically generated molecules and

intermediates.Thesecondobjectiveistodevelopacatalyticcycleinorganometallicchemistryandtodetermine

the appropriate analytical methods for the mechanistic study of a catalytic reaction by transition metal

compounds.

Prerequisites:

Teachinglanguage:

Documents,website:


2A

S4MH24OP.BIA

Modernanalyticalchemistryforbiotechnologyandclinical

diagnosticsKeywords:analyticalsystems,processminiaturization,engineering,innovation

Responsible:Fannyd'OrlyéMaîtredeconférences

[email protected]


work

Mentoring Evaluationmethod:finalwrittenexamwith

documents

10.5h 9h 4.5h

Courseoutline:

The developments and trends in modern analytical chemistry are going toward process simplification,

automationandminiaturizationwhilepreservingtheperformanceandreliabilityofanalyticalresults.Possibilities

anddifficulties inherent inminiaturizationateachstepofanentireanalyticalprocessarequitedifferentand

shouldbeaddressed.Thus,themaingoalofthiscourseistoprovideacomprehensiveoverviewofthecurrent

innovations in the field of analytical systems. The final objective is presented as the development of

micro(nano)sensorsandmicrototalanalysissystems(µTAS)forbiotechnologyandclinicaldiagnosticapplications.

Learningobjectives:

The coursewill focusonnewanalytical andbioanalytical tools allowing thedownsizingof several laboratory

functions (sample introduction, treatment, separation, detection) in order to handle extremely small fluid

volumesbutalsotointegrateaforementionedlabprocessesonaminiaturizeddeviceofafewsquarecentimeters

toachieveautomationandhigh-throughputscreening.Themaintopicsofconcernforthestudentswillbe1)New

functionalized nanomaterials for diagnosis: nano-supports (nanoparticles, nanotubes, monoliths, molecular

imprintedmaterials …), selective agents (antibodies/proteins, aptamers, chelating agents…) and conjugation

procedures; 2)Developments inminiaturized separationmethods (chromatographicor électrokinetic)mainly

based on molecular recognition to purify, concentrate and isolate analytes of interest; 3) Detection in

miniaturizedanalyticalsystems(optical,electrochemical,massspectrometry);4)Analyticalapplicationsongoing

fromstandardbioassaystomicro(nano)sensorsandµTASforbiotechnologyandclinicaldiagnostics.

Prerequisites:

basic notions in thermodynamics of solutions, non-covalent interactions, colloïds, electrochemistry and

separationméthods


Documents,website:handouts,publicationsandquizinenglish(website)


2A

S4MH24OP.CHE Chemistryprobesforbioimaging

Keywords:Bioimaging,chemicalprobes,fonctionalizing

Responsible:BichThuyDoanChercheurCNRS

[email protected]


work


21h 0h 2h

Courseoutline:

Thefieldofmedicalimaginghasbecomearealspecialtyandcutting-edgeresearchisperfectlyadaptedtothe

activitiesofuniversityandindustriallaboratories.Thedevelopmentofthisdisciplineiscloselylinkedtotheactive

developmentofnewprobestotargetorprobepathologicalbiologicaltissuesinordertoestablishaquantitative

diagnosis.Thisdiagnosisisevaluatedinvitro,invivoinpreclinicaltoclinicalstudiesandassociatedwithindustrial

production.

Thefollowingfieldsof imagingwillbecoveredbychemistsorbiophysicists:Ultrasound,MagneticResonance,

NuclearMedicine,Optics,NanoparticleAgents,TheranosticsProbes(imaging+drug).Inaddition,molecularand

physico-chemicalcharacteristicswillberepresented.

Finally,someinvivobiologicalapplicationsforthedetectionofcancer,inflammationandtheimpactoftreatment

willillustratetheinterestinthediagnosisandtherapyoffunctionalizedprobes.

Learningobjectives:

Thestudentisfamiliarwithallcommercialimagingprobesusedinbioimagingaswellastheirinvitroandinvivo

applicationsinthebiomedicalormedicalfield.

Itincludestheiroperatingprinciples,andthebiophysicalorbiochemicalprinciplesoftheiroperation.

In the case of molecular probes, he can propose innovative solutions to develop them and explain how

functionalizedprobescanbedeveloped.

Prerequisites:

atleastbachelordegreeinphysicalchemistryandmolecularchemistry


Documents,website:


2A

S4MH24OP.BIC Basicconceptsofcellularbiology

Keywords:Cellbiology,Microbiology,Toxicology

Responsible:MINIERMichel

[email protected]


work


24h 4h 0h

Courseoutline:

Thiscourseteachesthebasicknowledgeoncellstructure,physiology,microbiology,proteinbiochemistryand

toxicology.

Thestructureandphysiologyoftypicallivingcellswillbepresented,inordertoclarifythesharedfeaturesand

thedifferencesbetweenbacteria,yeasts,microalgae,archaea,vegetalcells,mammalcells.Industrialapplications

arediscussed.

Thelectureswillalsopresentthebasicprinciplesandtheapplicationsofinstrumentalandmolecularmethods

usedfortheanalysisofbiomolecules.

Afocuswillbemadeontoxicology.Thisstartswiththeknowledgeofthebasicbiologicalmechanismsinvolved

whenatoxic(toxin,medicine,etc…)isabsorbedbytheorganism.

Learningobjectives:

Attheendofthisintroductorycourse,thestudentmustknowthebasicsofcellularstructures,physiologyand

microbiology.

Thestudentsunderstandsthephysiologyandtheexchangeofmatterandenergywithinacell.

Heknowsthebiochemicaleffectsofthetoxicologicalpropertiesofproteins.

Heisawareoftheimportanceofbiologyattheinterfaceofthephysicalandchemicalsciencesandunderstands

the challenges and role of life in industrial applications: biotechnologies aimed at producing chemical

components, fuelsandbio-sourcedmaterials, cosmetic industries insearchof"natural, sustainableandsafe"

ingredients, environmental protection through the development of non-toxic and biodegradable substances,

corrosionphenomena.

Prerequisites:

bachelorlevelinchemistry


Documents,website:


2A

S4MH24OP.ABC PracticalBiotechnology(PracticalLab)

Keywords:Practicalwork,biotechnology

Responsible:CorineMARIEMaitredeconférences

[email protected]


work

Mentoring Evaluationmethod:writtenreport

0h 0h 21h

Courseoutline:

Besideslecturesonbiologicalbasicconcepts,somespecificpracticesinmicrobiologyandbioprocessengineering,

andsomeparticularmethodsusedinenzymology,molecularbiologyandhistologyareworthyofbeingdirectly

experimentedbystudents.

-Basicinmicrobialculture:mediumpreparation,sterilization,inoculation

-Kineticstudyofmicrobialcultures:measurementofmicrobialbiomassbydifferenttechniques,determination

ofcarbonsubstrateandprincipalmetabolite(s)concentrationsatdifferentsamplingtimes.

ExampleofalcoholicfermentationandenzymeproductionbyB.circulans.

-Labellingandobservationofpro/eukaryoticcells.

-Bacterialproductionofarecombinantprotein.

-DeterminationofMinimalInhibitoryConcentration(MIC)

-Studyofenzymaticreactions.

-Determinationoftheaerationefficiencyofafermentor.

Learningobjectives:

Regardlessof their futureprofessionalposition, thestudentsmustbeawareof theconstraintsrelatedtothe

manipulation,useandinactivationoflivingcells.

Theymustbeabletotaketheseconstraintsintoaccountwhenmanagingprojectsdealingwithbiologicalissues.

Prerequisites:

bachelorlevelinchemistry


Documents,website:


MATERIALSOPTION

2A

S4MH24OP.PH3 PhysicsIII:ElectronicPropertiesofSolids

Keywords:bandstructure,electricalandopticalproperties,semiconductors,devices

Responsible:LaurentBinetMaîtredeConférences,Chimie-ParisTech

[email protected]


work


18h 4.5h 0h

Courseoutline:

The objective of this course is to describe the electronic structure of solids and the main properties and

applicationsresultingfromthem,withanoverviewofcurrenttechnologicaldevelopments.

Inthefirstpartitintroducesthebasicconceptsontheelectronicbandstructuresofsolidsandshowshowthese

conceptsexplainthemajorfamiliesofproperties,electrical,opticalandchemicalofsolids.

Inthesecondpart,thecoursefocusesonanimportantclassofmaterials,semiconductors,anddescribesindetail

thephenomenathatoccurinap-njunction.Theapplicationsofsuchjunctionsaredescribed,inparticularsolar

cells,light-emittingdiodesandlaserdiodes.

Learningobjectives:

Thestudentmustbeabletodo:

- todefine thecharacteristicsof the twomainmodelsofelectronic structureof solidsand toknow inwhich

contexttoapplythem,

-explainthemainparametersthatgoverntheelectricalandopticalpropertiesofmaterialsandthefactorsthat

haveapositiveornegativeeffectontheseproperties,

-interpretabandstructurediagramofasolidanddeduceitselectricalandopticalbehaviour,

-describeindetailtheelectronicprocessesoccurringinthemainsemiconductordevicesandexplainthefactors

controllingtheirperformance

-toestablishastructure-propertyrelationshipforagivenapplication.

Prerequisites:

Quantumphysics,quantumchemistry,crystallography,electromagnetism,BSclevel


Documents,website:https://coursenligne.chimie-paristech.fr


2A

S2MH24OP.NOR Inorganicchemistry:frommoleculestomaterials

Keywords:


[email protected]


work

Mentoring Evaluationmethod:multiplechoicequestion30mn

9h 9h 0h

Courseoutline:

Theobjectiveofthiscourseistogivetherulesofconstructionofallinorganicandmineralsystemsbutalsoto

show how much this inorganic chemistry is alive and has many applications in current problems (energy,

environment, information storage, nanotechnologies...). An introduction to the industrial mineral chemistry

industrycompletesthecourse(cements,glasses,aquaticchemistry,batteries).Thetheoreticalpartfocuseson

transitionmetalandlanthanidecomplexesanddescribesinparticulartheiropticalandmagneticproperties.

Learningobjectives:

At the end of the course, the student knows the periodic table and the trends of the different elements

(ionization, complexation, orbital levels). He can describe amineral system and choose between two simple

approachestodescribe inorganiccomplexesaccordingtotwoionbindingorcovalentbindingmodels.Hecan

explainthestabilityandreactivityofinorganicmoleculesbasedmainlyontransitionelementsorelementsofthe

p-block.

Prerequisites:

atomistics,chemicalbonds,crystalfieldtheory


Documents,website:handoutshttps://coursenligne.chimie-paristech.fr/enrol/index.php?id=308


2A

S4MH24OP.COR Corrosion(ElectrochemicalStabilityofMaterials)

Keywords:

Responsible:KevinOgleProfesseur

[email protected]


work

Mentoring Evaluationmethod:Exam

15h 0h 0h

Courseoutline:

Optimizing the functional lifetime of amaterial is a fundamental driving force for the development of new

materialsandinfacthasbeenapreoccupationofourcivilizationfromprehistorytothepresentday.Thiscourse

willsurveythemechanismsthatdeterminethestabilityandreactivityofmetallicmaterialsincontactwithdiverse

environments.Wewillevokeanumberofcriticalquestions:Howcanwepredictthelifetimeofmaterialsingiven

applicationsandenvironments?Howcanweapply short term tests topredict the long termbehaviorof the

materials?Howcanweincorporateanticorrosionconceptsdirectlyintothedesignofanewmaterial?

Wewillseekabalancedpresentationbetweenfundamentalphysicalchemistryusefulforsimulationofcorrosion

problemsandthemoreintuitiveapproachoftenusedinindustry.Differentviewpointswillbedevelopedwithan

emphasisontheperspectiveofthedeveloperofnew,innovativematerials.

Theclasswillbeginwithathoroughreviewoftheelectrochemicaltheoryofcorrosion.Wewillthenapplythe

theorytoaninterpretationofcorrosionmechanismsfocusingonthedynamicsofthecorrodingsystem,reviewing

inturndiverseformsofcorrosionfordifferentmaterialsandenvironments.Thiswilltakeusfromthesimplest

caseofuniformcorrosiontocomplexmaterial/environmentalinteractionsleadingtoahighdegreeoflocalized

damage. Special emphasis will be placed on the importance of passive film stability and metallurgical

microstructure.Thesignificanceofcorrosionresistancerelativetootherphysicalpropertiesofthematerialwill

beemphasized.

Complexenvironmentswillalsobeconsideredsuchasoccurduringatmosphericcorrosionwhenmaterialsare

exposed to rapidly changing and/or cyclic environments.Wewill also reviewexamples of how anticorrosion

conceptsmaybe introduced intothedesignofnewmaterialsandassembliesofmaterials includingpassivity,

inhibitors,andgalvanicprotection.As timepermitswewillalsodiscusscoatings includingmetals,oxidesand

polymers and take a look at themechanismsof corrosion at themetal/oxide /polymer interface for painted

materials.

Learningobjectives:

Recognizethevariousformsofaqueouscorrosion.

Identifythecorrosionriskforselectedmaterialsandenvironments.

Understandthefundamentalchemical/electrochemicalmechanismsofcorrosion.

Applytheelectrochemicaltheoryofcorrosionto identifymechanismandpredictmaterial lifetimes inagiven

environment.

Incorporateanticorrosionoroptimizedcorrosionconceptsintothecriteriaofmaterialchoiceanddesign.

Prerequisites:

Electrochemistry,physicalchemistryofsolutions,introductorymetallurgy


Documents,website:


2A

S4MH24OP.MOD Modeling



[email protected]


work


4.5h 0h 9h

Courseoutline:









Learningobjectives:





Prerequisites:




2A

S4MH24OP.MM Surfacepropertiesandenduranceofmaterials

Keywords:surfacecharacterization,nanostructure,reactivity

Responsible:FrédéricWiameMaîtredeConférences

[email protected]


work

Mentoring Evaluationmethod:writtenfinalexam

19.5h 3h 0h

Courseoutline:

Whatisasurface?Whatarethespecificitiesofsurfacescomparedtobulk?Whyandhowtostudythesesurfaces?

Inthiscoursewewilltrytoanswerthesequestions.Theconceptsofsurfaceenergyandstresswillbeintroduced

andtheireffectsonthestructureandpropertiesofthesurfacewillbestudied.Theinitialstagesofreactivitywill

becharacterizedintheframeworkoftheadsorptiontheory.

Thecoursewillbeillustratedbypracticalexamples:growthofanoxideonanalloy,evolutionofametalinterface

in thepresenceof sulfur. Theseexampleswill highlight thedifferent information that canbeobtainedusing

surfacecharacterizationtechniques.Nanostructuredsurfacefabricationmethodswillalsobepresentedandthe

effectsofnanostructuringonsurfacepropertieswillbediscussed.

Afterhavingseentherelationshipmicrostructure-mechanicalpropertiesofmetals,weproposeheretogofurther

bylookingatthemechanismsthatleadtothebreakingofmaterialswhenexposedtomechanicalloadingoraging

inadefinedenvironment.Thiswillallowustoaddresstheissuerelatedtothedurabilityofmetallicmaterialsin

conditionsofuse.

Learningobjectives:

Attheendofthecoursethestudentwillbeable:

- toidentifyandexplainthemaintechnologicalissuesofthestudyofsurfaces,

- to describe the fundamental differences between the properties of a surface and those of the bulk

material,

- todeterminethestructure,characteristicsandbasicpropertiesofasurfaceofgivenorientation,

- todescribethedifferentadsorptionmechanismsandgivetheirmaincharacteristics,

- tojustifytheusefulnessofultra-highvacuumandelectronicspectroscopiesforsurfaceanalysisandto

identifythemostappropriatetechniquestoansweragivenproblem,

- tohighlight,bymeansofexamples,theimportanceofthestructureandthesurfacecompositiononthe

mechanismsandthekineticsofreactivity.

Prerequisites:


Documents,website:documentsinenglish


2A

S4MH24OP.ELA inorganicmaterialselaboration

Keywords:inorganicsynthesis,ceramic,monocristallinesynthesis;thinfilms

Responsible:GiaumeMaitredeConférences

[email protected]


work

Mentoring Evaluationmethod:writtenfinalexam

21h 1.5h 0h

Courseoutline:

Thiscoursepresentsthefundamentalsofmaterialselaboration.

Afirstpartpresentsthebasicsofmonocristallinesynthesis,startingfromreflexionbasedonphasediagrams,

nucleation-growthconceptsandillustrationswithvarioushot-temperaturemonocristallineroutes.Suchroutes

arepredominant in theoptic andphotovoltaic domains.A secondpart dealswith thephysical and chemical

principlesunderlyingthesolid-statedensificationandsinteringofpowderstoobtaintechnicalceramics.Technical

ceramics are awide family of high-valuematerials for structural or functional applications (magnetic, optic,

dielectric…).On the other hand, glass and glass-ceramics arematerials prepared from the liquid state. Their

elaborationisbrieflypresentedattheendofthispart..Thethirdpartconcernsthesynthesisofsmallinorganic

materialsbylowtemperatureroutes.Basicsofaqueousprecipitation,sol-gelcondensation,high-boilingsolvent

synthesisarethoroughlydescribed,followedbythepresentationofdifferentmethodsforachemistconcerning

thespecificelaborationofthinorthickfilms.

Learningobjectives:

Attheendofthiscourse,thestudents:

1) areawareofthevarioussynthesisroutestoelaborateinorganicmaterials;

2) Canevaluatetheprosandconsofaspecificsynthesisroute;

3) canchosethemostadaptedsynthesisroutefortheirstudy;

4) understandthemechanismsinvolvedinthevarioussynthesisroutes;

5) proposeconsistentmodificationofthesynthesis.

Prerequisites:


Documents,website:englishdocuments

https://coursenligne.chimie-paristech.fr/course/index.php?categoryid=11


2A

S4MH24OP.MAT Practicalworkinmaterialsscience

Keywords:materialsscience,preparation,characterization,project

Responsible:PascalLoiseauMaîtredeConférences

[email protected]


work

Mentoring Evaluationmethod:report

0h 0h 30h

Courseoutline:

Thispracticalworkinmaterialssciencehappensinsecondyear.Itisa4daysprojectbasedonatopicalissuethat

thestudentsmustappropriate.Toadressthisissue,thestudentsmusttomobilizemanyskillsdevelopedinfirst

andsecondyearatChimie-ParisTechinordertoproposerelevantexperimentalprotocolsandcharacterization

techniques.

Learningobjectives:

Fromthispracticalwork,thestudentwillbeableto:

-conceiveandprepareamaterialaddressingsomedesiredproperties

-applyrelevantcharacterizationtechniquesforadesignedmaterial

-proposesomeoutlookaimedtooptimizeamaterialonthebasisofstructure-propertiesrelationships

Prerequisites:

preparationofmaterials,characterization,propertiesofmaterials


Documents, website : scientific articles and technical documentation https://coursenligne.chimie-

paristech.fr/course/view.php?id=298


PROCESSOPTION

2A

S4MH24OP.SP Processsimulation

Keywords:processsimulation,economicanalysis,materialbalance,energybalance

Responsible:CédricGuyonMaîtredeconférencesChimieParistech

[email protected]


work

Mentoring Evaluationmethod:30%written,10%TP,60%oral

3h 0h 21h

Courseoutline:

Theobjectiveofthistrainingistosimulatearealindustrialprocessusingcommercialprocesssimulationsoftware

(AspenHysys). Itwill involvechoosingunits (reactions, separation),optimizing theoperatingparametersand

evaluating theunit'sperformance (production, selectivity,efficiency,etc.) according to the specifications set.

Once theseparameters havebeenestablished, studentswill have to evaluate the economicpotential of the

processstudied(AspenIcarusandbibliographicdata).

Learningobjectives:

Studentswhohavecompletedthiscoursewillbeableto:

-Tocarryoutamaterialbalanceonaglobalprocess

-Tosimulateanindustrialprocessonalargecommercialsoftwareinstaticmode(Aspenplus,AspenHysys)in

ordertooptimizetheoperatingparametersoftheprocessaswellaspossible

-To establish an economic balance of the process (energy costs, CO2 emissions, revenues, expenses, salary,

installationcosts,incometaxes...)

Prerequisites:

Processsimulationbaseacquiredduringthe2ndyearpracticalwork


Documents,website:englishpdfhttps://coursenligne.chimie-paristech.fr/course/view.php?id=299


2A

S4MH24OP.COR Corrosion(ElectrochemicalStabilityofMaterials)

Keywords:

Responsible:KevinOgleProfesseur

[email protected]


work

Mentoring Evaluationmethod:Exam

15h 0h 0h

Courseoutline:

Optimizing the functional lifetime of amaterial is a fundamental driving force for the development of new

materialsandinfacthasbeenapreoccupationofourcivilizationfromprehistorytothepresentday.Thiscourse

willsurveythemechanismsthatdeterminethestabilityandreactivityofmetallicmaterialsincontactwithdiverse

environments.Wewillevokeanumberofcriticalquestions:Howcanwepredictthelifetimeofmaterialsingiven

applicationsandenvironments?Howcanweapply short term tests topredict the long termbehaviorof the

materials?Howcanweincorporateanticorrosionconceptsdirectlyintothedesignofanewmaterial?

Wewillseekabalancedpresentationbetweenfundamentalphysicalchemistryusefulforsimulationofcorrosion

problemsandthemoreintuitiveapproachoftenusedinindustry.Differentviewpointswillbedevelopedwithan

emphasisontheperspectiveofthedeveloperofnew,innovativematerials.

Theclasswillbeginwithathoroughreviewoftheelectrochemicaltheoryofcorrosion.Wewillthenapplythe

theorytoaninterpretationofcorrosionmechanismsfocusingonthedynamicsofthecorrodingsystem,reviewing

inturndiverseformsofcorrosionfordifferentmaterialsandenvironments.Thiswilltakeusfromthesimplest

caseofuniformcorrosiontocomplexmaterial/environmentalinteractionsleadingtoahighdegreeoflocalized

damage. Special emphasis will be placed on the importance of passive film stability and metallurgical

microstructure.Thesignificanceofcorrosionresistancerelativetootherphysicalpropertiesofthematerialwill

beemphasized.

Complexenvironmentswillalsobeconsideredsuchasoccurduringatmosphericcorrosionwhenmaterialsare

exposed to rapidly changing and/or cyclic environments.Wewill also reviewexamples of how anticorrosion

conceptsmaybe introduced intothedesignofnewmaterialsandassembliesofmaterials includingpassivity,

inhibitors,andgalvanicprotection.As timepermitswewillalsodiscusscoatings includingmetals,oxidesand

polymers and take a look at themechanismsof corrosion at themetal/oxide /polymer interface for painted

materials.

Learningobjectives:

Recognizethevariousformsofaqueouscorrosion.

Identifythecorrosionriskforselectedmaterialsandenvironments.

Understandthefundamentalchemical/electrochemicalmechanismsofcorrosion.

Applytheelectrochemicaltheoryofcorrosionto identifymechanismandpredictmaterial lifetimes inagiven

environment.

Incorporateanticorrosionoroptimizedcorrosionconceptsintothecriteriaofmaterialchoiceanddesign.

Prerequisites:

Electrochemistry,physicalchemistryofsolutions,introductorymetallurgy


Documents,website:


2A

S4MH24OP.MOD Modeling



[email protected]


work


4.5h 0h 9h

Courseoutline:









Learningobjectives:





Prerequisites:




2A

S2MH24OP.NOR Inorganicchemistry:frommoleculestomaterials

Keywords:


[email protected]


work

Mentoring Evaluationmethod:multiplechoicequestion30mn

9h 9h 0h

Courseoutline:

Theobjectiveofthiscourseistogivetherulesofconstructionofallinorganicandmineralsystemsbutalsoto

show how much this inorganic chemistry is alive and has many applications in current problems (energy,

environment, information storage, nanotechnologies...). An introduction to the industrial mineral chemistry

industrycompletesthecourse(cements,glasses,aquaticchemistry,batteries).Thetheoreticalpartfocuseson

transitionmetalandlanthanidecomplexesanddescribesinparticulartheiropticalandmagneticproperties.

Learningobjectives:

At the end of the course, the student knows the periodic table and the trends of the different elements

(ionization, complexation, orbital levels). He can describe amineral system and choose between two simple

approachestodescribe inorganiccomplexesaccordingtotwoionbindingorcovalentbindingmodels.Hecan

explainthestabilityandreactivityofinorganicmoleculesbasedmainlyontransitionelementsorelementsofthe

p-block.

Prerequisites:

atomistics,chemicalbonds,crystalfieldtheory


Documents,website:handoutshttps://coursenligne.chimie-paristech.fr/enrol/index.php?id=308


2A

S4MH24OP.OCP Optimizationandprocesscontrol

Keywords:designofexperiments,linearregression,regulation,PIDcontroller

Responsible:JeromePULPYTELMaîtredeConférencesSorbonneUniversité

[email protected]


work

Mentoring Evaluationmethod:writtenexam(100%)

6h 18h 0h

Courseoutline:

Thiscourseisdividedintwoparts.Thefirstconcernthedesignofexperiments.Thisstatisticalandmathematical

methodallowstoreducethenumberofexperimentsandtooptimizemultifactorialprocesses.Thestudentswill

practice “classical” design such as full factorial, fractional factorial and central composite design, as well as

statisticstointerprettheresults.

Thesecondpartisdedicatedtothemethodsusedtocontrolprocesses.Regulationisindeedakeyparttoensure

thequalityandsafetyofindustrialprocesses.Openloopandclosedloopfeedbackcontrolwillbediscussed,and

especially thePID (proportional-integral-derivative) controller developed in the1920’s for themanufacturing

industryandwhicharenowadaysuseduniversallyforautomaticcontrol.

PracticalexercisewillbecarriedoutwithMatlabandNemrodw.

Learningobjectives:

Studentswillbeabletodefineanexperimentaldesign, tochoosethebeststrategytooptimizeprocesses, to

calculatelinearregressionmodelandinterprettheresultsusingstatisticaltools.Theywillknowhowtoidentify

aregulationmethod,calculateandsetthecontrollingparameters.Theywillalsoexplainthedifferentmethods

tomeasurethefundamentalsphysicalparametersinachemicalprocess(flow,temperature).

Prerequisites:

none




2A

S4MH24OP.FLC Flowchemistry

Keywords:flowchemistry,processintensification,millireactors

Responsible:StéphanieOgnierMCF

[email protected]


work

Mentoring Evaluationmethod:writtenexamination(70%)and

practicalwork(30%)

15h 3h 3h

Courseoutline:

Process intensificationispartofaneffortto improvetheproductivityandselectivityofchemicalreactions, in

particularthroughtheuseofmicro/micro-structuredreactors,in-situreaction/separationcouplingandtheuse

ofalternativeenergysources(photochemistry,ultrasoundetc...).Theteachingwillincludeafirsttheoreticalpart

whose objective is to show how the intensification of transfers within a chemical reactor influences its

performance.Inthisfirstpart,concreteexampleswillbeanalyzedinclass,intutorialsandpracticalwork.The

secondpartwillbemoredescriptiveandinvolveteachersandresearchersfromdisciplinesotherthanprocess

engineering(materials,molecularchemistry).Theywillsharetheirexperiencesasusersofthenewintensified

technologies.

Learningobjectives:

Theobjectiveofthisteachingunit istotrainstudents inthefieldofprocess intensification.Attheendofthe

training,studentsmustbeableto:

•Understandthecontextofintensification

•Describethefundamentalsofmaterial,heatandmomentumtransfer,especiallyinsmallchannels

•Analyzereferencedindustrialcasesanddevelopmentsinchemicalengineering

•Analyzeacademicexamplesofflowchemistryinthefieldsofmolecularsynthesisandmaterialsynthesis

•Proposerelevantintensificationsolutionsinthecaseofagivenprocess

Prerequisites:

fundamentalsinfluidhydrodynamics,massandheattransfer,reactionengineering


Documents,website:coursetransparencies,statementsoftutorialsandpracticalwork


2A

S4MH24OP.PRO Experimentaltrainingforflowchemistry

Keywords:flowchemistry,micro-reactor,reactionengineering

Responsible:CédricGuyonMaîtredeconférencesChimieParistech

[email protected]


work

Mentoring Evaluationmethod:100%TP

0h 0h 30h

Courseoutline:

ThisexperimentaltrainingisofferedaspartoftheFlowChemistryoptioninChemicalEngineeringfor2ndyear

studentsatschool.Ittakestheformofapracticalworkcourse

The teacher will first introduce the different miniaturized reactors and the control system (flow control,

temperaturecontrol,etc.)forthesereactors.Then,thestudentswillrealizeaflowchemistryset-upwithglass

micro-reactors,foraparallelreactionsystem.Theconceptsof"residencetime","mixingtime"willbepresented

duringthecourse,andtheadvantagesanddrawbacksoftheminiaturizedreactorwillalsobediscussed.

Learningobjectives:

Theobjectiveofthisteachingunitistogivestudentspracticalskillsinflowchemistry.

Attheendofthecourse,studentswillbeableto:

-Carryoutacontinuousflowchemistryset-up

-Characterizethemixing/reactiontimeinaminiaturizedreactor

-Establishthematerial/energybalancesinareactivesystem

-Comparedifferentreactors(miniaturizedreactorandbatchreactor)foraparallelreactionsystem

-Discusstheadvantagesand/ordrawbacksoftheflowchemistrysystemcomparedtoconventionalreactors

-Chooseasuitablereactorforagivenprocess

Prerequisites:

ChemicalEngineering1&2year




MOLECULARCHEMISTRYOPTION

2A

S4MH24OP.HC Heteroelementsandappliedcatalysis

Keywords:catalysis,transitionmetals,couplingreactions,heteroelements

Responsible:PhannarathPhansavath

[email protected]


work

Mentoring Evaluationmethod:Finalwrittenexam(1.5h)

15h 7.5h 0h

Courseoutline:

TheChemistryofheteroelementscourseaimstopresentthedifferentmethodsofpreparationofphosphorus,

sulfur and silicon reagents as well as the main transformations carried out with these compounds, with

applications in total synthesis. The objective of the Applied Catalysis course is to provide the basis for

organometallic chemistry involving transition metals (palladium, rhodium and ruthenium) as a tool for the

developmentofsyntheticprocesses.Couplingreactionsandothermajorapplicationsinhomogeneouscatalysis

arepresentedwithemphasisonreactionmechanisms,butalsoonapplicationsbothattheindustriallevelandin

thesynthesisofnaturalmoleculesormoleculesofbiologicalinterest.

Learningobjectives:

At the end of the course, the student will be able to master the methods used to carry out the main

transformations carried out with phosphorus, sulphur or silicon derivatives, and will be able to explain the

correspondingreactionmechanisms.Hewillbeabletousetheappropriateorganometalliccomplexestocarry

outthemaincouplingreactionsandothermajorreactionsusedinhomogeneouscatalysis.

Prerequisites:

Good knowledge of the basic reactions of organic chemistry and good understanding of classical reaction

mechanisms


Documents,website:


2A

S4MH24OP.CBI

BioinorganicChemistryKeywords:MedicinalInorganicChemistry,BioorganometallicChemistry,Bioinorganic

Chemistry,InorganicChemicalBiology.

Responsible:GillesGasser

[email protected]


work

Mentoring Evaluationmethod:WrittenExam.

15h 0h 0h

Courseoutline:

Natureutilizesmetalionsandmetalcomplexestoundertakeseveralcrucialprocesses.Infact,ahumanbeing

requiresabout25elementstohaveahealthylife,halfofthembeingmetals!Thechemicalstudyofmetalsin

biologyisreferredasbioinorganicchemistry.Thisareaofresearchencompassesthestudyofmetallo-enzymes

(i.e.vitaminB12)orbiologicalprocessessuchas respiration. In thiscourse,ageneraloverviewof the roleof

metals in biology will be presented. It is also planned to outline to role that metal complexes can play to

understandbiologicalprocesses.

Learningobjectives:

The course will be divided into twomain sections. In the first section, the role of metal ions in a few key

metalloproteinsandbiologicalprocesseswillbeexplained.Thesecondsectionwill focusontheuseofmetal

complexestodetectspecificorganelles/biomolecules,oradiscussiontounderstand/modifybiologicalprocesses.

Alargeemphasiswillbeplacedonexperiments,whichhavebeencarriedoutinlivingcellsororganisms.

Prerequisites:

Thiscourserequiresbasicknowledgeofinorganicchemistryandbiochemistry.


Documents,website:


2A

S4MH24OP.MOM MolecularModeling

Keywords:


[email protected]


work


4.5h 0h 9h

Courseoutline:









Learningobjectives:





Prerequisites:




2A

S4MH24OP.COM OrganometallicChemistry

Keywords:


[email protected]


work

Mentoring Evaluationmethod:Writtenexamination

7.5h 7.5h 0h

Courseoutline:

Thiscoursedescribesthefundamentalreactionsoftransitionmetalcomplexesandsome(industriallyrelevant)

catalyticcycles.Thiscourseprovidesanintroductiontocatalysisasatoolforthedevelopmentofcleanandenergy

efficientsynthesisprocesses.

Learningobjectives:

The first objective of this course is to rationalize the reactivity of catalytically generated molecules and

intermediates.Thesecondobjectiveistodevelopacatalyticcycleinorganometallicchemistryandtodetermine

the appropriate analytical methods for the mechanistic study of a catalytic reaction by transition metal

compounds.

Prerequisites:

Teachinglanguage:

Documents,website:


2A

S4MH24OP.SAR AsymmetricSynthesisandRetrosynthesis

Keywords:

Responsible:SylvainDarses

[email protected]


work

Mentoring Evaluationmethod:Writtenexam

15h 7.5h 0h

Courseoutline:

Principles and tools in retrosynthesis and organic synthesis. Generalities, examples of disconnections and

reconnections.Strategies:convergence,selectivities,cascadereactions,syntheticequivalents,polarityinversion.

Activationmethods,protection/deprotectionofthemainfunctionalgroups.Thecontrolofchirality.Resolution

(chemical,enzymatic,chromatographic).Theuseofchirons.Theuseofchiralauxiliaries.Asymmetriccatalysis.

Selectedapplicationsinthepharmaceuticalandagrochemicalindustrywilldocumentthiscourse.

Learningobjectives:

Torecognizetheimportanceofchiralityinorganicsynthesisandforthebioactivityofmolecules.Toanalyzeand

understandtheelementsofstereochemistryofthereactions.Toknowthemainasymmetriccatalyticornon-

catalyticsynthesismethodsusedinthepharmaceuticaloragrochemicalindustry.Torecognizeandanalyzekey

milestonesandimportantmotivesinmulti-stepasymmetricsyntheses.Toplanaviablesyntheticstrategyfora

targetmoleculebyperformingconsistentdisconnections,andproposingadetailedsyntheticapproach.

Prerequisites:

Basicstereochemistry,basesofkineticsandthermodynamics,basicorganicsynthesis,organometallicchemistry.


Documents,website:


2A

S4MH24OP.MOL Experimentaltraininginmolecularchemistry

Keywords:

Responsible:SylvainDarses

[email protected]


work

Mentoring Evaluationmethod:Laboratorywork:theoretical

andpracticalunderstanding,techniques,

productivity,behavioral,writtenreport.

0h 0h 60h

Courseoutline:

Preparationofexperimentaldesign:bibliographicresearch,choiceofmethod,reactionmechanism,assessment,

security elements related to manipulation. Preparation and maintenance of a laboratory notebook. Good

laboratory practices and health and safety rules. Starating and performing the synthesis steps. Isolation and

purifications.Chemical,physicochemicalandstructuralcharacterizations.Writingareport.

Learningobjectives:

Theaimoftheexperimentaltraininginmolecularchemistryistobringthestudent,throughanindividualwork

orinpairs,toanimprovementofhistheoreticalandpracticalknowledgeinmolecularchemistry.Themodulewill

consist of a short-project (a few reaction steps), related to the teaching module for which the student is

responsibleininteractionwithasupervisingteacher.Thestudentwillhavetoprovideareportontheworkdone.

Thisformofeducationaimstogivethestudentacertainformofautonomyandresponsibilityinhisworkinthe

laboratory,aworkcloselyrelatedtothatoftheindustry.

Prerequisites:

Molecularchemistrycourses,priorexperienceinmolecularchemistrylaboratory.


Documents,website:


BIOTECHNOLOGIESOPTION(ESPCI)

OptionoccurringattheESPCIengineeringschool

Presentation:

The3rdyearoftheESPCIBiotechnologycourseoffersafullyinterdisciplinarycourse,combiningbasic

knowledge(finance,microfluidics,statistics,etc.),specificcourses(molecularbiotechnology,synthetic

biologyandsystems),andapanelofoptionsallowinganexhaustiveexplorationofthedifferentinterfaces

withbiology..:Physics(MechanicsofLife,Biophysics,ComplexWaves,MedicalImaging),Physico-

chemistry(ColloidsandBiomolecules),analyticalchemistry(Bioanalytics,complexsamplesand

miniaturization)andchemistry(OrganicChemistryandHeterocyclicChemistry,InorganicChemistry).This

courseprovidestheappropriateluggagetoconsideralltheinterfacesofBiologywithothersciences,

whetherforengineeringorresearch.

Program:

MANDATORYCOURSES:

- English21h

- FundamentalsofFinance14h

- Microfluidics17h

- Statistics10h

- Statisticsandmodelling12h

- Chemometrics12h

- BigData14h

- SyntheticBiologyandSystems36h

- ColloidsandBiomolecules11h

- MolecularBiotechnology17h

- Biophysics14h

- LifeMechanics15h

- Bioanalysis,complexsamplesandminiaturization12h

OPTIONS:

- SoftMatterandDevelopment-Rheology28h

- MeasurementPhysics13h(+18hTP)

- OrganicChemistryandHeterocyclicChemistry24h

- MedicalImaging18h

- ComplexWaves12h

- InorganicChemistry12h


2A

S4MH24ES.SI

Technical2Ainternshipinalaboratoryand/orcompanyKeywords:technicalinternship,experimentation,discoveryoftheprofessional

environment

Responsible:ChristopheThomas,MariaMalheiroProfesseur

[email protected];[email protected]


work

Mentoring Evaluationmethod:report50%Oralpresentation

50%

h h h

Courseoutline:

Forfivemonths,thestudentperformsapracticalinternshipinacompanyorresearchlaboratoryduringwhich

heappliesthetheoretical,scientificandtechnicalknowledgeacquiredduringhisschoolyearsinthedomainof

hisspecialty.Aspartofateam,heorshecarriesoutamissionundertheresponsibilityofasupervisor.

Forengineeringstudentsonly:Atleastoneofthetwosecondorthirdyearinternshipsmustbecompletedina

company.Atleastonelong-terminternationalexperience(atleast5months)isalsorequired,eitherintheform

ofoneofthetwointernships2Aor3Aoramobilityofatleastonesemestertofollowtheoreticalcoursesabroad.

Learningobjectives:

Thestudentmustmasterthemethodsandtoolsadaptedtohismissionbyunderstandingthetheoreticalbases

oftheiroperation.

Itmustdevelopanexperimentalapproachbycollectingdatawithscientificrigour.Hemustbeabletoanalysehis

resultsandsynthesizethem.Hemustlearntoaccountforandexposehisworkthroughawrittenreportandan

oralstatement.

Hemustadapt to the lifeofhiscompanybyunderstanding its strategy.Hemust respect theconstraintsand

requirementsofhiscompanybyintegratingintoateamandadaptingtothehumanrelationsofhisworkplace.

Prerequisites:

scientificandtechnicalknowledgeatmasterlevel

Teachinglanguage:frenchorenglishasapropriate

Documents,website:


ADDITIONALCOURSES

•ATHENSWeek(semester3)

Presentation

ThisweektakesplaceintheEuropeanGrandesEcolesanduniversitieswhichconstitutetheATHENS

network,itallowsyoutochoosecourseswhichyoudonotfollowinyourcourses.Severalofthese

coursesaregivenbyprofessorsfromtheacademicsectorandexpertsfromtheindustrialworld.

Responsible:[email protected]

ECTScredits:2

•PSLWeek(semester4)

Objectives:Acquisitionofskillsandknowledgecomplementarytotheirfieldofspecialization

-mobilityofstudentsbetweenPSLschools

-toencourageinteractionbetweenengineeringstudentsinPSLschools

Program:DuringthePSLweek,studentsfollowoneweekofclassesatChimieParisTechorin

anotherPSLestablishment:ESPCI,laFemisorMinesParistech.Thisweekofcoursesisanopening

weekwhereengineeringstudentscanstudyafieldrelatedtochemistry,infundamentalorapplied

sciences,butalsoinprojectmanagement,suchasDrugsandpathologies,Technologiesand

Innovation,Historyofscience,Designofinnovativeproducts,Thevalueofwater,Processesand

microfluidics...Theform,contentandassessmentofeachweekdependonthecourseweekchosen.

ECTScredits:2

•Additionnalforeignlanguage(s):

FrenchasForeignLanguage

Description:Lecturesfocuson:

1)theabilitytofollowandparticipateinsciencecourses:oralandwrittencomprehension,written

andoralproduction

2)communicationwithFrenchstudentsandsociallifeinFrance,inordertofacilitateintegrationinto

theSchoolandinFrance

Culturalactivities(museumvisits)maybeorganisedtohelpstudentlearningFrench

Objective:TogetatleastB2levelinFrenchorC1

Knowledge:Dependsonthelevel

Skills:Understandingoftheeverydaylanguagethroughfilm,radioortelevisionbroadcasts

Improvementofwritingskillsthroughwritingandrewritingworkshops.

Abilitytolistenandexpressoneselfisencouragedthroughexercisestosummarizeaudio-visual

programmes,anddebates,thepresentationofcultural"PowerPoints"giventostudentsinsmall

groups-2groups(B1andB2)–2hperweekpersemester

Spanish

German

Chinese

Japanese

Russian

Portuguese

Italian

Arabic

Responsible:[email protected]

ECTScredits:1

•SportECTScredits:1