Top results
untitledubiquitin chains earmark gpcrs for bbsome-mediated removal from cilia swapnil rohidas shinde, andrew r. nager, and maxence v. nachury regulated trafficking of g protein–coupled
the role of gpcrs in neurodegenerative diseases: avenues for therapeutic interventionthe role of gpcrs in neurodegenerative diseases: avenues for therapeutic intervention
opioid receptors belong to the large superfamily of seven transmembrane spanning (7tm) g protein-coupled receptors (gpcrs). as a class, gpcrs are of fundamental physiological…
the origin of gpcrs: identification of mammalian like rhodopsin, adhesion, glutamate and frizzled gpcrs in fungi arunkumar krishnan., markus sällman almén., robert fredriksson,…
jo ur na l o f c el l s ci en ce research article plasma membrane translocation of redd1 governed by gpcrs contributes to mtorc1 activation grégory michel1 hans w d matthes1…
mecanismos de comunicação celular 26/05/2015 hopkins & groom (2002) nature reviews drug discovery 1:727 alvos terapêuticos elementos da comunicação celular ligante…
mechanismen der agonist-selektiven phosphorylierung und dephosphorylierung von somatostatin-rezeptoren dissertation zur erlangung des akademischen grades doctor rerum naturalium…
trends sleep disturbances are associated with increased risk for type 2 diabetes t2d. enhanced sympathetic tone, desyn- chronization of tissue circadian clocks, abnormal…
biomolecules review in silico drug design for purinergic gpcrs: overview on molecular dynamics applied to adenosine and p2y receptors veronica salmaso and kenneth a. jacobson
expression map of 78 brain-expressed mouse orphan gpcrs provides a translational resource for neuropsychiatric researchexpression map of 78 brain-expressed mouse orphan gpcrs
© heptares therapeutics 2018 the heptares name, the logo and star are trade marks of heptares therapeutics ltd heptares therapeutics is a wholly owned subsidiary of sosei…
r e s e a r c h a r t i c l e i m m u n o l o g y coincident signals from gpcrs and receptor tyrosine kinases are uniquely transduced by pi3kb in myeloid cells daniel m houslay1*…
using molecular fields for rational drug design against gpcrs: application to cck2 antagonists george buckleya tim cheeserighta mark mackeya james melvillea sally rosea andy…
eighth annual gpcr-based drug discovery inaugural antibodies against membrane protein targets - part 1 september 24 - 25 2013 inaugural gpcr-targeted therapeutics inaugural…
research open access abstract background: recent successes in the determination of g-protein coupled receptor (gpcr) structures have relied on the ability of receptor variants
1 rational drug design lecture 9 Łukasz berlicki drug molecular targets � g-protein coupled receptors gpcr are one of the main classes of molecular targets 2 drugs �…
volume 5 • issue 4 • 1000192cardiovasc pharm open access issn: 2329-6607 cpo an open access journal open access kim et al cardiovasc pharm open access 2016 5:4 doi: 1041722329-66071000192…
mol #99671 1 ligand residence time at gpcrs – why we should take our time to study it c. hoffmann, m. castro, a. rinken, r. leurs, s.j. hill, h.f. vischer bio-imaging-center/rudolf-virchow-zentrum…
1 thermal unfolding of gpcrs application note nt-pr-008 nanodsf: label-free thermal unfolding assay of g protein- coupled receptors for compound screening and buffer composition…
1 jason kahn: g proteins and gpcrs ii 1 g-proteins and gpcrs ii review of g-protein regulation gpcr dimerization and networking gpcr pharmacology ras proteins:…