School of Medicine Shared Resource Facilities

•The School of Medicine provides direct support and oversight to 21 SOM shared resource facilities.

•Their purpose is to provide investigators within the Penn community access to scientific services widely required in the conduct of biomedical research but which are too costly for individual investigators or departments to bear.

•Oversight is provided by the School of Medicine Research Core Facilities Committee, which is led by an Associate Dean for Research Core Facilities.

Contributions of PSOM to Cores

FY07 FY08 FY09 FY10 FY11 FY12

Investments via Core Committee

$250,000 $250,000 $250,000 $250,000 $250,000 $250,000

Other Core Investments $700,000 $300,000 $312,428 $420,585 $420,585 $637,095

PSOM Support for Renovations

$1,493,448

$445,000

PSOM Support for Equipment $328,296 $413,890 $119,702$1,956,87

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Total Expenditures$2,443,44

8$1,323,29

6$562,428

$1,084,475

$790,287$2,843,97

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Reporting Structure

Dean Perelman School of Medicine

Office of Research Program Development

Combined Degree and Physician Scholar ProgramsBiomedical Postdoctoral Programs

Executive Vice Dean and Chief Scientific Officer

Office of Corporate AlliancesGlobal Health Programs

Associate Dean for Research Core FacilitiesMorris J. Birnbaum, M.D., Ph.D.

Biomedical Graduate Studies

Office of Human Research

Office of Masters Programs

Research Planning and Management

Executive Director: Education, Financial Planning and Management.

Associate Dean for Research at the Philadelphia VA Medical Center

Associate Dean for Translational Research

Associate Dean for Research Program Development

Senior Executive Director of Research & Research Training

Assistant Dean for Animal Research

Academic Support Programs

Research Core Facilities Committee

• 15 member committee representing various departments and areas of science

• Meets once a month

• Conducts reviews of core performance

• Evaluates core equipment and financial requests

• Requests an in-depth annual report every March

• Considers potential cores that should be developed

Cores Committee Members

Morrie Birnbaum, IDOMMichael Feldman, Path & Lab MedYale Goldman, PhysiologyMichael Granato, CDBKate Nathanson, MedicineNancy Speck, CDBBob Vonderheide, MedicineJohn Wherry, Microbiology

Admin Support: Dorothy Leung

Perelman School of Medicine CHOP

Tom Curran

Wistar

Bill Wunner

Ex Officios

Kathy Bramwell, FinanceSusan Passante, EVD/CSOBrian Wells, IT & Research Computing

Abramson Cancer Center

Barbara Vance

Reviews and Requests Process

Among the key considerations of the review process:

Determine how valuable the to the community, both now and in the future

Examine how well the Core is providingthe service

Determine whether the Service is affordable to Penn PIs

Consider ways to provide additional support

Biomedical Core Resources

Behavioral Testing UnitCell Center ServicesCell Center StockroomClinical Cell and Vaccine Production

FacilityClinical Research Computing UnitConfocal CoreDNA Sequencing Facility Gene Targeting ServiceElectron Microscopy CoreFlow Cytometry and Cell Sorting

Research LabHuman Immunology CoreInvestigational Drug ServiceMolecular Profiling CoreNext Generation SequencingProteomics and Systems Biology CoreResearch Instrumentation ShopSmall Animal Imaging Facility CoreStem Cell and Xenograft CoreTransgenic and Chimeric Mouse CoreTranslational Core LaboratoryVector Core

Bio-bankingBioinformaticsHigh throughout screening

Current Medical School Cores Cores in Development

New

Under review

www.med.upenn.edu/cores/

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Considerations in using Cores for large projects

• Is there sufficient money budgeted?

•Should there be funds for infrastructure?

•Does the Core have sufficient capacity?

•Can the Core supply necessary supporting material for grant application?

• Is the charge-back scheme compliant?

OMB Circular A-21

OMB Circular A-21