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SadgamayaVeterinarian’s Annual Convention 2016

The Veterinarian’s Annual Convention “Sadgamaya” will be held at RUBCO Auditorium, Kannur from 31-12-

2016 to 02-01-2017. Veterinarians of Kerala will assemble in unison to commemorate their annual convention. The

convention, among other things gives us an opportunity to meet and socialize, share thoughts and exchange ideas,

discuss problems and evolve solutions so that we may extend our limits both as individual and as professionals. Scientific

sessions focussing on contemporary issues, cultural events and annual general body meetings of Indian Veterinary

Association and Kerala Government Veterinary Officers Association will be conducted during these days. The organizing

committee of Sadgamaya on behalf of the aforementioned organizations earnestly request honour of your presence and

invite you with family to the annual convention.

Dr. M. Kesavan Kutty Dr. V. Prasanth

Chairman Gen. Convener

Dr. V. Chandramohananan Nair Dr. K.R. Arunkumar

President, IVA President, KGVOA

MAJOR EVENTS

Dec 31 Technical Seminar

Executive Committee Meetings

Jan 1 Inaugural Session

Release of Souvenir

KGVOA Award Banquet

Farewell to Retired Veterinarians

Annual General body Meeting – KGVOA

Sightseeing Trip

Cultural Programmes

Jan 2 Annual Generalbody Meeting – IVA

IVA Award Banquet

Release of IVA Diary

Valedictory Function

How to reach RUBCO AUDITORIUM, South Bazar, Kannur.

Just off the NH17, 5 minutes drive from Railway station andwalkable distance from KSRTC Bus stand, Caltex Junction.

For accommodation, contact:Dr. Anilkumar K.P., Mob: 9847082667, Email: vetsconkerala2016@gmail.com.

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DISTRICT NEWSPATHANAMTHITTA

IVA,Kerala Pathanamthitta unit organized a CVE

programme on ABC-AR on 05 th October at the

conference hall of District Veterinary Complex. The

session was presided by Dr. Sisy Philip, President IVA,

Pathanamthitta. Dr. Satheesh, Secretary, KGVOA welcomed

the gathering. Dr. Saiprasad, General Secretary, IVA, Dr. M.

Mathew, President, KGVOA and Dr. Aleyamma Abraham,

District Animal Husbandry Officer offered felicitations.

The technical session was handled by Dr. Kishore Kumar,

Project Co-ordinator, ABCD, Kochi. The systematic

approaches followed in Kochi model was discussed. The

importance of waste management and licensing of pets

along with ABC –AR was pointed out in the discussions.

The session came to an end with vote of thanks by Dr.

Anupama, Treasurer, IVA, Pathanamthitta.

IVA,Kerala Pathanamthitta unit organized a familytour to Hyderabad.

KOTTAYAM

World Rabies day @Kottayam

EDUCATE- VACCINATE- ELIMINATE- This years

slogan for the world rabies day celebrations. IVA Kottayam

unit decided to celebrate the day by spreading this

message to the next generation. A school from every taluk(

five taluks) was selected by the taluk units and district

unit arranged the faculty for a session with the students.

The program turned up to be a eye opener and revealed

the role of vets in stray dog control. We could realize

that no one can discuss the matter effectively other than

a vet. Our focus was to create an awareness on three

points

1. Responsible dog ownership( vaccination, licensing andbirth control of home kept dogs) was discussed

2. Effective waste management

3. Animal birth control in stray dogs

Some very useful tips to avoid dog bites was

discussed and it generated a lot of interest among the

listeners. The response towards the program was beyond

our expectation. Young minds had some brain teasing

questions for our faculty. We could understand that even

the present issue of stray dog menace have not evoked a

urgency for anti rabies vaccination of home kept dogs.

The students are well aware that waste management is

very much important for the control of stray dogs.

Kottayam district unit is very much thankful to our taluk

units and the faculty for making this initiative a success.

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A CVE on “ Role of vets in meat inspection’ was

conducted at vets home Kottayam on 1ST October. Dr.

Binduraj, VS , VD Panachicadu led the CVE. It was a highly

informative session with an energy packed discussion from

the audience. Various doubts regarding the Vetero - Legal

aspects of meat inspections was discussed in detail. Sixty

five members participated in the CVE.

A CVE on “ Standard operating procedures in bovine

infertility” was held on 16Th October at Vets home ,

Kottayam. Dr. Kiren Menon ,MVSc(Vety Gynaecology) led

the informative session. Various aspects and recent trends

in treatment of bovine infertility was dealt. It was a

refresher as well as downpour of new ideas in the subject.

39 members participated in the program

IDUKKI

A send off meeting was organized for the vets who

got transferred from Idukki to other districts on 06th

October 2016 at Hotel Sicilia Auditorium. Dr. Jacob Mathew,

Dr. Shejo Jose, Dr. Anees were the doctors who got

transferred from Idukki last month. The meeting was chaired

by Dr. P. V. Narendran (President, IVA Idukki). Dr. Mariyamma

Thomas (State Committee member, IVA, Kerala) welcomed

the gathering. Felicitations were offered by Dr. Dinesh, Dr.

Sheela Saly, Dr. Lal. G. Mathew, Dr. Justin Jacob Adhikaram

(President, KGVOA Idukki), Dr. Joby K J & Dr. Krishnadas

(Secretary, IVA Idukki). Dr. Geethamma (State Committee

member, KGVOA) presented mementos to Dr. Jacob

Mathew. Dr. Shejo Jose & Dr. Anees could not attend the

function due to unavoidable reasons. Dr. Rajesh P B

(Secretary, KGVOA Idukki) offered vote of thanks after

the reply speech by Dr. Jacob Mathew. A class on Income

tax and TDS E filing was organized on the same day in

association with KGVOA Idukki and was handled by Sri.

Manikantan. P., Regd. Tax Practitioner from Thrissur. Total

23 vets participated in the class and was quite informative.

MALAPPURAM

IVA-KGVOA combined general body meeting for the

month of October was held at Hotel Prasanth Malappuram

on 5th October 2016. The function was started with a silent

prayer and Dr. Preetha Skaria administered veterinarian’s

6Oath. The function was presided by Dr. P. U. Abdul Asees, President IVA,Kerala, Malappuram unit and Dr.P.Karthikeyan,

Secretary IVA Malappuram welcomed the gathering. A class on “Global Veterinary Medical Perspective: Concept of One

health, and Zoonotic pathogen :Public health implications” was presented by Dr. Ramees. T. P Vety Surgeon Niramaruthur

as part of CVE Programme. Dr. Reshmi introduced the faculty and Dr. Suresh. B was the moderator of the session.

District Animal Husbandry Officer Dr.George.P.John presented certificates to ten veterinary surgeons from Malappuram

district who participated in the World rabies day state seminar at COVAS Pookode and. Dr. Regitha Joseph shared the

knowledge gathered from the seminar with the audience. DAHO presented memento to the vets who got transferred

to other district from Malappuram. The programme was felicitated by Dr. Meera Mohandas (DD(AH) Malappuram),Dr.

George. P. John(DAHO Malappuram), Dr. Jancy (CVO Malappuram) Dr.Ajay Kumar(Secretary, KGVOA),and Dr. Jithendra

Kumar. Vote of thanks was delivered by Dr. Rajeesh.

KANNUR

A combined general body of IVA,Kerala and KGVOA Kannur units was convened on 03rd October 2016 at Hotel

Royal Omars to discuss the progress of preparations for the annual convention. The building committee secretary, Dr.

M.P Girish Babu briefed the audience regarding acquisition of a plot for the construction of IVA building at Kannur.

Raising various issues, Dr. K.J Varghese, Vice President (IVA), North Zone; Dr.M. Kesavan Kutty, Chairman, Sadgamaya;

Dr.Beetu Joseph, President, KGVOA, Kannur unit; Dr.T.V Unnikrishnan, DD (AH); Dr.M.P.Sujan and Dr. C.P Dhananjayan

also spoke during the occasion.

A CVE program on ‘Setting up of operation theatre

and anesthesia protocols in small animals’ followed the

general body. The scientific session was handled by Dr. M.K

Narayanan, Assistant Professor, KVASU. The program

focused on layout of operation theatre and the specific

anesthesia requirements for different surgical procedures

in small animals. Other procedures for ABC program was

also dealt with in the session. Several members participated

7actively in the discussion which followed the presentation.

A memento was presented to the speaker by Dr. K.J

Varghese, Vice President (IVA), North Zone. Earlier, the

audiences were welcomed by Dr. Pramod S, Secretary,

Kannur unit. The program was presided by Dr. Prasanth V,

President, Kannur unit. Vote of Thanks was delivered by

Dr. O.M Ajitha, executive member of IVA, Kannur Unit.

Thailand Tour of Kannur Vets:

With an aim to provide chance to members for an

abroad trip, Indian Veterinary Association, Kannur unit has

organized a Thailand trip from 7th October to 13th October.

17 Vets with their family members (total 45) participated.

Reached Bangkok on 8th morning. On the way to Pattaya

from Bangkok, team visited Sri Racha Tiger Zoo and enjoyed

Crocodile show and Tiger show. Visited Noong Nooch

Tropical garden and later enjoyed super Elephant show,

with fascinating demonstrations by a large number of

elephants of different age group. Then visited Underwater

World with a collection of about 4500 different species

of fish and other marine life swimming around a 100 meter

long acrylic tonnel.In the evening really thrilled while

viewing famous Alcazar Show with beautiful cultural items

of Thailand.

On 10th morning started trip to Coral Island inspeed boats. On the way stopped for experiencingParasailing. The sudden flying with parachute above thesea was really an exciting experience. After that, some ofthe members enjoyed underwater ride. Then teammembers enjoyed a refreshing bath in the sea at CoralIsland. In the after noon started journey from Pattaya toBangkok. On the way visited Gems factory to know varioussteps in Gems mining and refining.

On 11th morning started trip to Floating Market.There members enjoyed shopping in a number of boatsfloating in artificially maintained water tunnel. Visited Buddhatemple which houses the world’s largest solid gold Buddha(5.5 tons of gold). In the afternoon members madeshopping from Indra Plaza Mall.

On 12th morning started trip to Marine Park andSafari World. In the Marine Park viewed various thrillingshows of Orangutan, Sealion,Dolphin etc. In the Safari world,team members could see large number of zebras, giraffes,tigers, birds etc free in their habitat.

Returned to Bangkok air port and flight was at9.50pm and arrived Nedumbassery air port on 13th

morning and reached home by around 7am.

Stayed 2 days at Pattaya and 2 days at Bangkok.Food and accommodation were of good standard. The firstforeign trip organized by IVA was really thrilling andinteresting. All the planning and arrangements for this tripwere efficiently oranised by Dr.M.Vinod Kumar

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NSAIDsIN CANINE CANCERCHEMOPREVENTION AND TREATMENT

Dr. Ranjith. D

Assistant Professor, Department of Veterinary Pharmacology and Toxicology,College of Veterinary and Animal Sciences, Pookode, Kerala

or progression of neoplastic cells to malignancy. It can

also be used in some apparently healthy dogs at risk

for cancer to prevent or reduce risk of developing

invasive disease. Currently, the effective

chemopreventive agents are non-steroidal anti-

inflammatory drugs (NSAIDs), peroxisome proliferator-

activated receptor-Ò ligands and dietary compounds.

Among which NSAIDs are widely used for palliating

carcinomas.

NSAIDs for a long time used in the treatment of

inflammatory diseases and were first recognized for

anticancerous activity after comparing incidences that

routinely use these agents. They act by inactivating

Cyclo oxygenase (COX, two isoforms namely COX-1

and COX-2). NSAIDs block both COX enzymes with

greater or lesser specificity, resulting in decreased

synthesis of prostaglandins, which plays a vital role in

inflammation.

During the recent years, numerous studies have

shown that NSAIDs are chemopreventive for

colorectal cancer and also for breast and lung cancer

in humans. Similarly, effects have also seen in dogs

administered with piroxicam for transitional cell

carcinoma. The beneficial effects of NSAIDs have been

established by multitude of population studies and

confirmed by two randomized clinical trials with

prodrug sulindac and celecoxib.

Meloxicam, piroxicam and carprofen are the most

commonly used NSAIDs prescribed in dogs. Meloxicam

has a greater selectivity for COX-2 in healthy dogs

Prevalence of canine cancer has become more

in recent years because of greater attention and

increased life expectancy of the pets. There is a

similarity between the range of occurrence of cancers

in both dog and human patients, despite more and more

intensive therapeutic interventions and fatality rates

remains high in both species. The commonly occurring

cancers in dogs include melanoma, non-Hodgkin

lymphoma, soft tissue sarcoma, osteosarcoma and

prostate, mammary, lung and colorectal carcinomas,

head and neck squamous cell carcinoma and transitional

cell carcinoma of the bladder. Approximately, 1 in 3 dogs

will be diagnosed with cancer during its lifetime and

currently accounts for about half of the deaths of all

dogs older than 10 years. Carcinogenesis and tumor

biological behavior in dogs have more features in

common with humans than with laboratory rodents,

similar tumour genetics, molecular phenotypes,

histological appearances, disease duration and response

to conventional therapies made them an identical

clinical model for knowing pathobiology of cancer.

More advanced cancers are incurable; hence it’s

important to prolong survival by blocking the process

of carcinogenesis through chemoprevention, which is

a feasible alternative in cancer prevention or inhibition

of tumor growth or metastasis. Chemoprevention is

therefore a vital means of encountering this disease,

because domestic pets share our environment for

dwelling. Therefore, study of pro-tumorigenic and anti-

tumorigenic factors in our shared environment will

benefitboth the species. The aim of the cancer

chemotherapy is to prevent, arrest or reverse the

initiation process of carcinogenesis

9whereas piroxicam and carprofen inhibit COX-2activity and induces apoptosis in cell culture. Piroxicamhas offered benefit both in alleviating symptoms due toinflammation as well as causing actual tumour shrinkageand also it resulted in remission of various cases ofinvasive transitional cell carcinoma of the urinarybladder in dogs. Some recently published papers inveterinary literature suggested that by combiningpiroxicam with either mitoxantrone or carboplatinchemotheraphy provides additional benefit byincreasing survival time from 6 month to 12 month.

A recent study (Aug.24, 2015: UNC LinebergerComprehensive Cancer Centre researchers andDenmark researchers) reported continuous use of lowdose of aspirin and non-aspirin NSAIDs associated withdecreased colorectal cancer risk. Colorectal neoplasmsis the third most common non-skin cancer in the worldand have a progression, making cancer an obvious targetfor preventive interventions. But, more research isneeded to determine the optimal dose and duration ofuse for this purpose. Besides, the U.S. PreventiveServices Task Force recommends routine use of aspirinor NSAIDs to prevent colorectal cancer in individualsat average risk for the disease.

According to study findings published in theAnnals of Internal Medicine, 75 to 150 mg of aspirinusage continuously for five years or longer period hada 27% lower risk for colorectal cancer compared tocontrol group. However, more than five yearscontinuous use of non-aspirin NSAIDs (Ibuprofen) wasassociated with a 30-45% reduction in colorectal cancerrisk and also non-aspirin NSAIDs with highest COX-2enzyme selectivity were associated with largest riskreductions.

Experimental studies:

In-vitro studies:

Much of the recent evidences indicates that mostof NSAIDs inhibit cell proliferation in vitro. However,these effects are influenced by factors like micromolardrug concentrations, duration of treatment and timepoint at which anti-proliferative effects are assayed.

In-vivo studies:

APC min mouse is used as a genetic model for in-

vivo studies because it closely mimics human familial

adenomatous polyposis. Much of the available data

suggests administration of NSAIDs in these animals has

been shown to associate with inhibition of either

initiation or progression of polyps and reduction in

tumour load.

NSAIDs and Other Cancers:

Extensive literature reviewed on the relationship

between various NSAIDs and other cancers of skin,

stomach, breast, prostate, pancreas, ovary and urinary

bladder. Some epidemiological studies have found that

aspirin may be useful in populations with a high risk of

developing prostate cancer. Conflicting outcomes also

reported from the use of NSAIDs in breast cancer, there

is still insufficient data on risk benefit profiling for the

use in cancer chemoprevention.With non-colorectal

cancers, the mechanisms by which NSAIDs affect

tumour behaviour are also variable and include

disruptions of signalling pathways and metabolism of

other therapeutic agents.

Conclusions:

1. At a befitting concentration in vitro, most of the

NSAIDs inhibit proliferation in colon cancer cell

lines.

2. Many NSAIDs will prevent tumorigenesis and

slow carcinogen growth in animal models but

limited data relating to its ability to inhibit tumour

proliferation.

3. Studies have also proved that low dose use of

aspirin and non-aspirin NSAIDs related with

decreased colorectal cancer risks.

4. A distinction between acute effects and adaptive

effects that are observed when treatment is given

over weeks and months may be necessary in order

to allow more useful appropriate comparisons

between data sets.

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Animal Lifting Device

Department of Animal Husbandry, Kerala is now equipped with Animal Lifting Device. The

equipment has been designed with the help of Centre for Development of Advanced Computing(C –

DAC), Thiruvananthapuram. The equipment is now available with District Veterinary Centres of

Thiruvananthapuram, Ernakulam, Palakkad, Kannur and Wayanad. The equipment was supplied to Kollam

last year.

The first One Health Day

to be held on 3rd November 2016

Global “One Health Day” is planned

by three international one health groups

on 3rd November 2016. Three leading

international One Health groups, the One

Health Commission, the One Health

Initiative Autonomous pro bono Team, and

the One Health Platform Foundation are

partnering to create a global “One Health

Day”.

Additional information is available online

at www.onehealthday.org

10th Poultry India Exhibition

Poultry India, an international standard

exhibition for the poultry industry is

going to be held in the City

of Hyderabad, India from 23rd to 25th

November 2016. This event is a wide

forum with valuable information about

poultry industry, feed equipments,

technology, breeders, Egg farming,

poultry nutrition, animal health and

international poultry production. It also

offers latest advances in poultry

research, science and technology like

cages and feed milling importance. It

also offers advanced knowledge and

understanding of poultry industry via

scientific forums, trainings and career

opportunities in the Poultry Industry.

For more details -

http://www.poultryindia.co.in/

OBITUARY

Dr.P.Rajagopalan Nair (72)

19643batch, Retd. Scientific

Officer of Hindustan Antibiotics

Limited, Pune passed away on 8th

October 2016. He was cremated

May his soul rest in peace

at Thattayil, Pathanamthitta. He is survived

by his son, a medico at Muttuchira Holy Cross

hospital, Kottayam.