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Chronic Diseases in ChildrenRobert C Dumont, MD and Youngran Chung, MD
CEDH International Conference Chicago, 2016
5th International CEDH Conference - June 24-26, 2016
Approaching the Young ChildFirst meeting: sizing up the child
5th International CEDH Conference - June 24-26, 2016
Interactions
The Child is the most important person in the Room
Size up the child and interact with him/her first
Begin forming a sense of his “energy”, constitutional/behavioral style
80-90% important elements of an exam can be from simple
observation.
Recognize their developmental level (and where they are at the
time emotionally) and interact at that level
Remember parents will often tell you only the things they believe are
important you or they believe is related to that particular complaint
To Treat the Child, First Treat the Mother (parents)
5th International CEDH Conference - June 24-26, 2016
Respiratory
Gastrointestinal
Dermatology
Other
Pediatrics
Behavior
5th International CEDH Conference - June 24-26, 2016
Common Pediatric issues
Respiratory
URIs
Otitis media
Allergic Rhinitis
Sinusitis
Bronchitis/pneumonia
Bronchiolitis
Asthma
Gastrointestinal/nutritional
GERD/Upper GI dyspepsia
Recurrent abdominal pain/IBS
Constipation
Diarrhea
Failure to gain weight/feeding problems
Dermatology
Eczema
Acne
Other Rashes
Neurologic/Behavior
• ADHD
• Autism
• Tantrums and ODD
• Insomina/parasomnias
Other
Endocrine
Dysmenorrha
Genitourinary
Urinary tract infections
Enuresis
5th International CEDH Conference - June 24-26, 2016
Clinical Homeopathic Approach
Histopathological or pathophysiological approach
Pathogenetic approach
Approach by the Chronic Reactional Mode (CMR)
Sensitive type (ST) approach
Etiological approach
5th International CEDH Conference - June 24-26, 2016
Stressful event
Strong Moderate Weak
Pathophysiologic reaction/symptoms
Disease is predominant Common disease expression with Individual expression
individual variation of symptoms is predominant
The range of disease and symptom expression
Etiology/Triggering event
Chronic Reactional Mode
(Sensitive Type)
Toxicology (detoxification)
5th International CEDH Conference - June 24-26, 2016
Pathogenic
Approach
Chosen
Medicine(s)
Pharmacology &
Toxicology
Clinical
Indications
(Experience)
“Herrings Cross”
Lesional stage,
tissues, location
Sensation
modalities
concomitant
symptoms
5th International CEDH Conference - June 24-26, 2016
Terrain Medicines:Chronic Reactional Mode
and Sensitive Type
It is more important to know what sort of person has a disease than to know what sort of disease a person has. -Hippocrates
5th International CEDH Conference - June 24-26, 2016
PSORIC
Arsenicum album
Hepar sulphuris
Lachesis
Lycopodium
Nux vomica
Psorinum
Sulphur
Graphites
Kali bichromicum
SYCOTIC
Causticum
Dulcamara
Natrum sulph.
Medorrhinum
Nitricum acidum
Thuja occ.
Rhus tox.
Phytolacca
Hydrastis can.
TUBERCULINIC
Arsenicum iod.
Calcarea phos.
Iodum
Natrum mur.
Phosphorous
Pulsatilla
Sulphur iod.
Tuberculinum
Argentum nit.
Ignatia
Drosera
Chronic reactional Modes Medicines
PSORO-SYCOTIC
Silicea
Calcarea carb.
Sepia
(Graphites)
5th International CEDH Conference - June 24-26, 2016
CRM in Children:
Tuberculinic
Recurrent ENT infections
Especially in thin
children with tendency
to lymph adenopathy
Arsenicum iodatum
Calcarea phosphorica
Iodum
Natrum muriaticum
Phosphorous
Pulsatilla
Sulphur iodatum
Tuberculinum
Argentum nitricum
Ignatia
Drosera
5th International CEDH Conference - June 24-26, 2016
CRM in Children:
Psoric
reactive mode or
reactional pattern
Skin, Mucous
membrane (and serous
membrane)
Inflammatory or
spasmodic (and
metabolic)
Family History
May have begun as
rash/eczema
Arsenicum album
Hepar sulphur
Lachesis
Lycopodium
Nux vomica
Psorinum
Sulphur
Graphites
Kali bichromicum
5th International CEDH Conference - June 24-26, 2016
CRM in Children:
Sycotic
The problem never
stops:
Chronic secretions (of
mucous membranes) -
rhinitis, chronic serous
otitis media…
There may be a
precipitating event
Causticum
Dulcamara
Natrum sulphuricum
Medorrhinum
Nitricum acidum
Thuja occidentalis
Rhus tox.
Phytolacca
Hydrastis canadensis
5th International CEDH Conference - June 24-26, 2016
And not to forget:
The Psoro-Sycotic Medicines
Silicea
Calcarea carb.
Sepia
(Graphites)
5th International CEDH Conference - June 24-26, 2016
A few Sensitive types
Phosphorus – may start out shy but then warms up
quickly
Pulsatilla – shy and often clingy (may see the mottled
legs)
Silicea – shy and lack of confidence
Sulphur- robust
Sulphur iodatum – mild Sulphur often with increased
energy with ENT issues (infections)
Calcarea carbonica – “steady”, may be fearful
Calcarea phosphorica – long and lanky, fatigue
Lycopodium – maybe quiet or open but often
correcting parents, emotionally sensitive – self esteem.
5th International CEDH Conference - June 24-26, 2016
Etiologic Treatment
vaccines
beginning daycare or school
repeated antibiotic treatments
recurrent infections
major and disturbing emotional events (divorce, new
child in family
Grief - Ignatia
Abandonment - Pulsatilla
Jealousy - Lachesis
5th International CEDH Conference - June 24-26, 2016
Gastroesophageal Reflux: A Way of Thinking
The phenomenon of refluxWe all have reflux
The manifestations of refluxHow does reflux present?
The root of reflux?What is causing the reflux
5th International CEDH Conference - June 24-26, 2016
GERD: Presenting Symptoms in Infants
Emesis/Spitting up
Regurgitation
Irritability
Feeding refusal/aversion
FTT/weight loss
Recurrent ear infections
Chronic sinus problems
Respiratory symptoms
Apnea
Reactive airway disease
Pneumonia
Hoarseness
Cough
5th International CEDH Conference - June 24-26, 2016
There May be One or More
Contributing Factors
Constipation (younger child) consider homeopathic treatment
Metabolic problems
Anatomic problems
Dysmotility
Protein intolerance/allergy (all ages)
Dysbiosis
Stress (older child, adolescent) – consider homeopathic treatment
5th International CEDH Conference - June 24-26, 2016
Dysmotility and ppi use are
independent risk factors for
small intestinal bacterial and/or fungal overgrowth
C Jacobs*, E Coss Adame+, A Attaluri*, J
Valestin*, and SSC Rao*,+
*Department of Internal Medicine,
University of Iowa Carver College of
Medicine, Iowa City, IA
+Department of Internal Medicine,
Georgia Regents University, Augusta, GA
Aliment Pharmacol Ther. 2013 June ;
37(11): 1103–1111. doi:10.1111/apt.12304.
5th International CEDH Conference - June 24-26, 2016
Gastroesophageal Reflux
and Dyspepsia
Aethusa cynapium
Sudden, profuse vomiting (projectile vomiting) right
after a meal or later (in clots)
with great efforts during vomiting
May see loose stools watery greenish stools or stools
with mucus
Aethusa plus Calcarea carbonica (agg. From starches
and milk,: atopic dermatitis, seborrheic dermatitis,
diaper rash)
5th International CEDH Conference - June 24-26, 2016
Intolerance to dairy
MAGNESIA CARBONICA Sour smelling baby, with low tone (weak muscles) aggravated by milk, may be cold sensitive.
May have frothy green diarrhea
Terrain: Calcarea carbonica)
Nux vomica
Dyspepsia – may refuse feeding
Irritable, hyperactive and impatient
May be colicky with abdominal distension, +/-vomiting
tendency to constipation
5th International CEDH Conference - June 24-26, 2016
Terrain medicines: Cow’s milk
allergy
Lycopodium
Sulphur
Calcarea carbonica
5th International CEDH Conference - June 24-26, 2016
Gastroesophageal Reflux
and Dyspepsia
Pyrosis
Robinia: Complement medicine, epigastric burning, <
eating esp. fatty foods, night time
Sulphuricum acidum: Tendency to develop oral aphthae) and acidic gastroesophageal reflux
(burning epigastric pain. Sour odor in babies.
Iris versicolor: Burning of entire tract, belching and
burping
5th International CEDH Conference - June 24-26, 2016
Gastroesophageal Reflux
and Belching
Asa foetida
eructation with GERD, esophageal spasms
Antimonium crudum
nausea and vomiting, excessive eating
tendency to overeat, coated tongue, taste-smell of food
eaten
Argentum nitricum
Loud belching, (inflammation, ulceration – pain)
5th International CEDH Conference - June 24-26, 2016
Tourette’s Syndrome and Tic
Disorders
Lycopodium (facial) Often the CRM medicine given weekly
Agaricus muscarinus (all tic disorders and choreiformmovements)
Mygale lasiodora (shoulder, neck)
Magnesia phosphorica (painful facial tics)
Manganum metallicum (throat clearing tic)
Ignacia (tics from emotional issues, hypersensitive, spasmodic)
Staphysagria (tics from held in emotions)
Ambra gresea
5th International CEDH Conference - June 24-26, 2016
“The organs weep the tears the
eyes refuse to shed”Sir William Osler
EK was a 13 year old with significant motor tics
Digging into family dynamics – conflict with mother
Treatment
Lycopodium 30C weekly
Staphysagria 30C 2 x daily and then tapering
Chronic need for Staphysagria while in mother’s house
10 years later – stable lifestyle engaged, steady job, without tics
5th International CEDH Conference - June 24-26, 2016
The Problem Child of Pediatrics:
Diseases of Immune
Dysregulation
5th International CEDH Conference - June 24-26, 2016
Homeopathy and immune
dysregulation
What we know
about Immune
dysregulation
What we know
about
homeopathy and
how it works
Homeopathic
Intervention in
diseases of Immune
Dysregulation
5th International CEDH Conference - June 24-26, 2016
Clinical Homeopathic Approach
Histopathological or pathophysiological approach
Pathogenetic approach
Approach by the Chronic Reactional Mode (CMR)
Sensitive type (ST) approach
Etiological approach
Clearance of substances, drainage, etc
5th International CEDH Conference - June 24-26, 2016
Immune Dysregulation
Environmental Allergy/Sensitivities
Food Sensitivities
Eczema
Asthma
Autoimmune Diseases
Ulcerative colitis
Crohn’s Disease
Autism
PANDAS
Rheumatoid arthritis
Alopecia
5th International CEDH Conference - June 24-26, 2016
From: Bach JF. The effect of
infections on susceptibility to
autoimmune and allergic
diseases. N Engl J Med. Sep
2002;347(12):911–920.
5th International CEDH Conference - June 24-26, 2016
Allergic Diseases
Presentation by
Cezmi A. Akdis
Swiss Institute of
Allergy and Asthma
Research
5th International CEDH Conference - June 24-26, 2016
It is not Nature vs Nurture
Instead: Nature + Nurture
5th International CEDH Conference - June 24-26, 2016
Systems Biology
“Medical practice is three dimensional chess and yet most practitioners are still playing checkers”
5th International CEDH Conference - June 24-26, 2016
Illnesses do not come upon us from out of the
blue. They are developed from small daily sins
against nature. When enough sins have
accumulated, illness will suddenly appear.
Hippocrates (400 B.C.)
Nurture
5th International CEDH Conference - June 24-26, 2016
“When a patient is sick, the doctor should first regulate the patient’s diet and lifestyle”
Sun Si-Miao
5th International CEDH Conference - June 24-26, 2016
Hahnemann on curable
and non curable disease
Those diseases are inappropriately named chronic, which
persons incur who expose themselves continually to
avoidable noxious influences, who are in the habit of
indulging in injurious liquors or aliments, are addicted to
dissipation of many kinds which undermine the health, who undergo prolonged abstinence from things that are
necessary for the support of life, who reside in unhealthy
localities, especially marshy districts, who are housed in
cellars or other confined dwellings, who are deprived of
exercise or of open air, who ruin their health by overexertion of body or mind, who live in a constant state
of worry, etc. These states of ill-health, which persons bring
upon themselves, disappear spontaneously, provided no
chronic miasm lurks in the body, under an improved mode of living, and they cannot be called chronic diseases.
5th International CEDH Conference - June 24-26, 2016
Environmental factorsDiet and lifestyle
Opportunity for new “targets”
5th International CEDH Conference - June 24-26, 2016
Nature + Nurture
Nurture:
Triggers (sycotic induction) - clearance of effects -
vaccines, viral infections, etc
Toxins, heavy metals, pesticides (detox, body of
substances and hepatic/renal clearance
Hygiene theory/Microbiome - parasites, dysbiosis and
regulation of immune system
Food sensitivities, leaky gut, mucosal integrity -
homeopathics?
Generation of an inflammatory state
Residual damage
5th International CEDH Conference - June 24-26, 2016
Functional Medicine
Lifestyle and Diet
Diet
Stress
Genetic predisposition
Sleep
Physical activity
Healthy Non Healthy
Environmental toxins
5th International CEDH Conference - June 24-26, 2016
Non Homeopathic
Interventions
Determine and eliminate “sensitive” foods (often Dairy
and Gluten)
Organic, nutrient rich anti-inflammatory and
microbiome supportive diet
Avoidance of Pollutants and toxicants
Adequate restful Sleep
Adequate Physical activity
Adequate periods of rest and relaxation
Supportive
5th International CEDH Conference - June 24-26, 2016
Toxins, pollutants and Heavy
Metals
“We’ve got 80,000 chemicals approved for use in
commerce, but we know very little about their
immune effects. Our lifestyles are also different than
they were a few decades ago, and we’re eating
more processed food.” Should prevalence rates for
heart disease and cancer continue their decline, Miller
says, autoimmune diseases could become some of
the costliest and most burdensome illnesses in the
United States.
Fred Miller, director, Environmental Autoimmunity Group at the
National Institute of Environmental Health Sciences in: volume 119
| number 6 | June 2011 • Environmental Health Perspectives
Environmental Factors in Autoimmune Disease
Charles W. Schmidt, MS
5th International CEDH Conference - June 24-26, 2016
Autoimmune Disease and
the Environment
Hereditability of the disease accounts for 50–60 % of its
variance, the HLA-DRB1 shared epitope–containing
allele being the strongest genetic risk factor
active and heavy tobacco smoking which is the most
important environmental risk factor for RA with its
attributable risk sustained for up to 20 years after
discontinuation
Sources of air pollution including traffic and probably
solid fuels are associated with Rheumatoid Arthritis
Is air pollution a risk factor for rheumatoid arthritis?
Mickael Essouma and Jean Jacques N. Noubiap. Journal of
Inflammation (2015) 12:48
5th International CEDH Conference - June 24-26, 2016
There is an association between
Autoimmune Disease and
environmental Toxicants
Hemdan NY, Emmrich F, Faber S, Lehmann J, Sack U. Alterations of TH1/TH2 reactivity by heavy metals: possible consequences include induction of autoimmune diseases. Ann N Y Acad Sci. 2007 Aug;1109:129-37.
Mishra KP. Lead exposure and its impact on immune system: a review. Toxicol In Vitro. 2009 Sep;23(6):969-72.
Bahadar H, Abdollahi M, Maqbool F, Baeeri M, Niaz K.Mechanistic overview of immune modulatory effects of environmental toxicants. Inflamm Allergy Drug Targets.2015;13(6):382-6.
Suzuki Y, Inoue T, Ra C. Autoimmunity-inducing metals (Hg, Au and Ag) modulate mast cell signaling, function and survival. Curr Pharm Des. 2011 Nov;17(34):3805-14.
5th International CEDH Conference - June 24-26, 2016
What works in the Biomedical
approach to Autism
74% of parents see behavioral improvement
in their children with chelation of heavy
metals
5th International CEDH Conference - June 24-26, 2016
Homeopathic medicines
used in Autistic Disorder
Treatment of Heavy Metals
Alumina
Cadmium sulphuricum
Mercurius solubilis
Plumbum metalicum
Arsenicum album
Petroleum?
5th International CEDH Conference - June 24-26, 2016
Infectious Triggers
Streptococcus
Epstein Barr virus
5th International CEDH Conference - June 24-26, 2016
Homeopathic medicines
used in Autistic Disorder
“Clearance” effect
Medorrhinum
Thuja
Vaccinotoxinum
Streptococcinum
Morbillinum
5th International CEDH Conference - June 24-26, 2016
Diet and Immune Dysregulation
“When diet is wrong, medicine is of no use; When diet
is correct, medicine is of no need.” – Ayurvedic
Proverb
Hippocrates has been quoted as saying “death sits in
the bowels” and “bad digestion is the root of all evil” (400
B.C.)
5th International CEDH Conference - June 24-26, 2016
Autoimmune Disease and
the Environment
Food Sensitivities
Individuals with autoimmune disease have food
sensitivities - There are many anecdotes of individuals
who show marked improvement or resolution of
symptoms of rheumatoid arthritis in conjunction with
elimination of a particular food. There are also many
individuals with autoimmune disease feel better when
consuming an anti-inflammatory diet, in conjunction
with fish oil supplementation.
5th International CEDH Conference - June 24-26, 2016
Food Sensitivities: Difficult
Eczema Case
17 year old girl with chronic resistant eczema (on body, limbs and face.
No response to conventional medications and no response to experimental medications.
Tried off of dairy, gluten no change
Combination of acupuncture and homeopathy (symptomatic and CRM): 40-50% improvement
Reassessment of treatment protocol (correct)
IgG sensitivity testing: Turkey
Off turkey and completely resolved in 3 weeks
5th International CEDH Conference - June 24-26, 2016
Microbiota
“The microbe is nothing, the soil is everything.”
- Louis Pasteur
« La bactérie n’est rien,
c’est le terrain qui fait tout. »
(Bacteria are nothing,
the terrain is everything)
Claude Bernard 1813 – 1878
“If I could live my life again, I would devote it to proving that germs seek their natural habitat – unhealthy tissue –rather than being the cause of unhealthy tissue.”
Rudolf Virchow (1821–1902)
5th International CEDH Conference - June 24-26, 2016
Histopathologic Approach:
Inflammatory Bowel DiseaseInflammation:
Argentum nitricum
Arsenicum album
Mercurius solubilis
Mercurius corrosivus
Nitricum acidum
5th International CEDH Conference - June 24-26, 2016