ppt t reg cells
TRANSCRIPT
CD4+CD25+ nTreg cells
Master switch of peripheral tolerance
Reliable biomarkers for CD4+CD25+ regulatory T cells?
CD25
CTLA-4GITR
CD103 Galectin-1
Ly6
OX-40
4-1BB
Unidentified X,Y,Z ??
Neuropilin-1
CD4+CD25+
RegulatoryT cell
Piccirillo et al. Trends in Immunology July 2004
NO marker after T cell activation.
Only in the naïve T cell repertoire.
Need better marker.