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Molecules of Life

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Page 1: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Molecules of Life

Page 2: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Elements of Life

Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Page 3: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Carbohydrates

Examples Bread, pasta, potatoes, sugar

Uses Energy storage The more complex the carbohydrate chain,

the longer it takes your body to break down -ose word ending Broken down into sugar (glucose)

Page 4: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Monosaccharide – 1 sugar

C6H12O6

Glucose, Fructose, Galactose, Ribose Cells use this to generate ATP

Page 5: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Disaccharide – 2 sugars

C12 H22O11 (C6H12O6 + C6H12O6 - H2O)

Sucrose (Glucose + Fructose) “table sugar”

Maltose (Glucose + Glucose) “malt sugar”

Lactose (Galactose + Glucose) “milk sugar”

Page 6: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Polysaccharide – many sugars

3 or more monosaccharides linked together Starch: energy storage in plants Glycogen: energy storage in animals Cellulose (plant fiber) (very long chain) Chitin (insect/crustacean outer covering)

Page 7: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S
Page 8: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Proteins or Polypeptides

Examples Nuts, meat (muscle), beans

Uses Muscle, hair, nails, skin, enzymes

Made from Amino Acid chains that can be thousands of amino acids long There are only 20 amino acids in nature!

Polypeptide: Many amino acids Tripeptide: Three amino acids Dipeptide: Two amino acids

Page 9: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S
Page 10: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Enzymes

Large, complex proteins –ase word ending (Lactase breaks down lactose) Activity varies with pH Can be denatured by extreme heat (shape is

changed) Can be reused over and over again “Lock & Key”

Active Site: attracts and holds only molecules that have the right shape

Substrate: molecule that is changed by the enzyme – must have the right shape

Page 11: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Enzmyes

Page 12: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Example: Lactose Intolerance

Lactose is a sugar found in most milk products

Lactase is an enzyme that breaks down lactose

People who are missing lactase (can no longer produce it) can’t eat lactose unless they get artificial lactase.

Page 13: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Example: Lactose Intolerance

Page 14: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Energy in Reactions

ENERGY is required for most synthesis reactions creation of a new, complex molecule

ENERGY is released in decomposition reactions Breakdown of complex molecules

Page 15: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Photosynthesis

6 CO2 + 6 H2O + (light E) → C6H12O6 + 6 O2

Stores light E as chemical E in GLUCOSEOccurs in chlorophyll pigment of green plants

Inside chloroplastsSource of E for almost ALL ORGANISMS

Page 16: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Cellular Respiration

Plants AND Animals respirate (breath) Releases stored chemical E from bonds of

glucose (mono-saccharides)

C6H12O6 + O2 → 6CO2 + 6H2O + 38ATP

Page 17: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Nucleic Acids

Building Blocks Your body builds nucleic acids from amino

acids that come from proteins

Uses DNA, RNA

Storage, transmission and expression of genetic information

Page 18: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

DNA/RNA

Outer Structure: Sugar

Ribose (RNA) Deoxyribose (DNA)

Phosphate

Inner Structure: 4 base pairs Nucleotides

DNA Chemical Structure

Page 19: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Fats or Lipids

Examples Butter and oils Steroids and hormones Wax

Uses Long term energy, cushion, insulation, waterproofing Contains more than twice as much energy as an equal

amount of carbohydrate

Page 20: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Structure of Fats

Made from triglycerides 1 glycerol 3 fatty acids

Types of fatty acids change how fats behave Saturated: solid at room temperature Unsaturated: liquid at room temperature

Page 21: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

TriglycerideGlycerol

3 Fatty Acids

Page 22: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Saturated Fats

All single C-C bonds Straight fatty acids can stack and clog

Animal Products: Meats (edge and marbling) Milk (cream and butter) Egg (the YOLK…the rest is protein)

Plant Products: Coconut, Palm and Cocoa “Butter”

Page 23: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Unsaturated Fats

Some double C=C bonds Causes bends: cannot stack, stay more liquid

Plant Products: Seeds and their oils Nuts and their oils

Can be HYDROGENATED Become more saturated/solid Vegetable oil, shortening, margarine

Page 24: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Other examples of fats

Hormones Steroids Cholesterol Plant waxes (think Bee’s wax)

Page 25: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Lipids

Page 26: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

ATP- adenosine triphosphate

Most important energy transfer compound in all organisms Undergoes a “small change” for temporary energy

storage

Cellular respiration releases energy from glucose and stores it in the bond holding the 3rd phosphate group ATP becomes ADP (THIS IS IMPORTANT!) Tri-phosphate becomes a Di-phosphate

Page 27: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

ATP Conversion to ADP

When a cell needs energy, it breaks the 3rd phosphate off ATP.

Adenosine P P P This creates ADP – Adenosine diphosphate ATP ADP + phosphate + energy Cell rebuilds ATP from ADP 38 ATP are obtained from 1 glucose molecule

during cellular respiration

Page 28: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Marathon Mouse

Page 29: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

Review

Page 30: Molecules of Life. Elements of Life Carbon - C Hydrogen - H Oxygen - O Nitrogen - N Phosphorous – P Sulfur - S

To give you a sense of scale…

http://learn.genetics.utah.edu/content/begin/cells/scale/