module 23
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Module 23. Mood Disorders & Schizophrenia. MOOD DISORDERS (CONT’D). Bipolar I disorder Marked by fluctuations between episodes of depression and mania Manic episode goes on for at least a week during which a person is unusually euphoric, cheerful, and high - PowerPoint PPT PresentationTRANSCRIPT
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Module 23
Mood Disorders & Schizophrenia
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MOOD DISORDERS (CONT’D)
• Bipolar I disorder– Marked by fluctuations between episodes of
depression and mania– Manic episode goes on for at least a week during
which a person is unusually euphoric, cheerful, and high
– Also has three of the following symptoms: great self-esteem, little need for sleep, rapid speech and frequently racing thoughts, easily distracted, and in constant pursuit pleasurable activities
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MOOD DISORDERS
– Prolonged, disturbed emotional state that affects almost all of a person’s thoughts, feelings, and behaviors
• Major depression– Major depressive disorder
– Marked by at least two weeks of continually being in a bad mood, having no interest in anything, and getting no pleasure from activities
– Four of the following symptoms: problems eating, sleeping, thinking, concentrating, or making decisions; lacking energy; thinking about suicide; feeling worthless or guilty
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MOOD DISORDERS (CONT’D)
• Dysthymic disorder– Characterized by being chronically but not continually
depressed for a period of two years– Person experiences at least two of the following: poor
appetite, insomnia, fatigue, low self-esteem, poor concentration, feelings of hopelessness
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MOOD DISORDERS (CONT’D)
• Causes of mood disorders– Biological factors underlying depression
• genetic, neurological, chemical, and physiological components that may predispose or put someone at risk for developing a mood disorder
– Psychosocial factors• personality traits, cognitive styles,
social supports, and the ability to deal with stressors interact with predisposing biological factors to put one at risk for developing mood disorders
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MOOD DISORDERS (CONT’D)
• Treatment of mood disorders– Major depression and dysthymic disorder
• antidepressant drugs• increase levels of a specific group of neurotransmitters (monoamines-
serotonin, norepinephrine, and dopamine) involved in the regulation of emotions and moods
• SSRIs– selective serotonin reuptake inhibitors– Prozac, Zoloft
• psychotherapy
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ELECTROCONVULSIVE THERAPY
• Definition and usage– Electroconvulsive therapy, or ECT
• involves placing electrodes on the skull and administering a mild electric current that passes through the brain and causes a seizure
• treatment consists of 10 to 12 sessions about three times per week
• used when antidepressant medication fails to decrease depression
• serious side effect of ECT is memory loss
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ELECTROCONVULSIVE THERAPY (CONT’D)
• Definition and usage– New treatment– Transcranial magnetic
stimulation (TIMS)• noninvasive
technique that activates neurons by sending pulses of magnetic energy into the brain
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PERSONALITY DISORDERS– Inflexible, long-standing traits that significantly impair
functioning or cause great distress in one’s personal and social life
• DSM-IV-TR describes 10 personality disorders– Seven of the most common types
• paranoid personality disorder– pattern of distrust and suspiciousness and perceiving
others as having evil motives
• schizotypical personality disorder– acute discomfort in close relationships, distortions in
thinking, and eccentric behavior
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PERSONALITY DISORDERS (CONT’D)
– Seven common types• histrionic personality disorder
– excessive emotionality and attention seeking
• obsessive-compulsive personality disorder
– intense interest in being orderly, achieving perfection, and having control
• dependent personality disorder– pattern of being submissive and
clingy because of an excessive need to be taken care of
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PERSONALITY DISORDERS (CONT’D)
– Seven common types• borderline personality disorder
– pattern of instability in personal relationships, self-image, and emotions, as well as impulsive behavior
• antisocial personality disorder– refers to a pattern of
disregarding or violating the rights of others without feeling guilt or remorse
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SCHIZOPHRENIA
• Definition and types
– Schizophrenia
• serious mental disorder that lasts for at least six months and includes at least two of the following symptoms: delusions, hallucinations, disorganized speech, disorganized behavior, and decreased emotional expression
• (HIGH LEVELS OF DOPHOMINE))
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SCHIZOPHRENIA (CONT’D)
• Subcategories of schizophrenia
– Paranoid schizophrenia
• characterized by auditory hallucinations or delusions, such as thoughts of being persecuted by others or thoughts of grandeur
– Disorganized schizophrenia
• marked by bizarre ideas, often about one’s body (bones melting), confused speech, childish behavior, great emotional swings, and often extreme neglect of personal appearance and hygiene
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SCHIZOPHRENIA (CONT’D)
• Subcategories of schizophrenia– Catatonic schizophrenia
• characterized by periods of wild excitement or periods of rigid, prolonged immobility
• sometimes the person assumes the same frozen posture for hours on end
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SCHIZOPHRENIA (CONT’D)
• Biological causes– Genetic predisposition
• Genetic markers– identifiable gene(s) or a specific segment of a
chromosome directly linked to some behavioral, physiological, or neurological trait or disease
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SCHIZOPHRENIA (CONT’D)
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SCHIZOPHRENIA (CONT’D)
• Neurological causes– Ventricle size
• 80% of brains of schizophrenics show larger than normal ventricles
– Frontal lobe: prefrontal cortex• less activation of the prefrontal cortex• frontal and temporal lobes are smaller
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SCHIZOPHRENIA (CONT’D)
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SCHIZOPHRENIA (CONT’D)
• Environmental causes– Incidences of stressful events and how individuals
cope– Hostile parents, poor social relations, the death of a
parent or loved one, and career or personal problems can contribute to the development and onset of schizophrenia
– Abstract thinking & planning– Diathesis stress theory
• some people have a genetic predisposition (a diathesis) that interacts with life stressors to result in the onset and development of schizophrenia
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More to follow……
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SCHIZOPHRENIA (CONT’D)
• Treatments– Neuroleptic drugs (also called antipsychotic drugs)
• used to treat serious mental disorders, such as schizophrenia, by changing the levels of neurotransmitters in the brain
– Typical neuroleptics• primarily reduce levels of the neurotransmitter
dopamine– Dopamine theory
• dopamine neurotransmitter system is somehow overactive and gives rise to a wide range of symptoms
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SCHIZOPHRENIA (CONT’D)
• Treatments– Atypical neuroleptics
• clozapine and risperidone lower levels of dopamine and also reduce levels of other neurotransmitters, especially serotonin
• reduce positive symptoms, may improve negative symptoms, and reduce relapse
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SCHIZOPHRENIA (CONT’D)
• Evaluation of neuroleptic drugs– Typical neuroleptics
• phenothiazines• can produce unwanted motor movements
– Tardive dyskinesia• appearance of slow, involuntary, and
uncontrollable rhythmic movements and rapid twitching of the mouth and lips, as well as unusual movements of the limbs
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DISSOCIATIVE DISORDER
• Definition– Characterized by a person having a disruption, split,
or breakdown in his or her normal integrated self, consciousness, memory, or sense of identity
• Dissociative amnesia– Characterized by the inability to recall important
personal information or events and is usually associated with stressful or traumatic events
• Dissociative fugue– Disturbance marked by suddenly and unexpectedly
traveling away from home or place of work and being unable to recall one’s past
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DISSOCIATIVE DISORDER (CONT’D)
• Dissociative identity disorder– Formerly called multiple personality disorder– Presence of two or more distinct identities or
personality states, each with its own pattern of perceiving, thinking about, and relating to the world