microscopes write down the stuff in green (minimum)
TRANSCRIPT
Look at your hand…
One square centimeter of skin contains more than 100,000 cells.
No matter how closely you look with your eyes, you won’t be able to see individual skin cells.
How the heck did we figure out they were there?
So who invented this technology? 100a.d. Romans began “blowing glass”
to make shapes.
They made glass by super-heating sand – Sweet Home Alabama story
So who invented this technology? The Romans began experimenting with
this blown glass and discovered that if you looked through curved glass, it made things look bigger.
So who invented this technology? Someone also discovered that you can
focus the rays of the sun with one of these special “glasses” and start a fire. These early lenses were called magnifiers or burning glasses.
A simple microscope like this one has only one lens.
Story of burning glass at mountain man rendezvous
So who invented this technology? The word lens by the way, is derived
from the latin word lentil, as they were named because they resembled the shape of a lentil bean.
So who invented this technology? Around 1250 spectacle makers were
producing lenses to be worn as glasses.
So who invented this technology? The early simple “microscopes” were
really only magnifying glasses and had a magnification power of 6x to 10x. One thing that was very common and interesting to look at was fleas and other tiny insects. These early magnifiers were hence called “flea glasses”.
So who invented this technology? Around 1590, a Dutch spectacle maker
named Hans Janssen put several lenses in a tube, created the first compound microscope, and discovered that he could see VERY tiny things.
Two or more lenses put together make a compound microscope.
So who invented this technology? Galileo, in Italy, heard about Janssen’s
new magnifier and began making refinements to his telescopes with the same ideas.
This “spyglass” was used on ships that visited Italy.
So who invented this technology? About 1660, an Englishman named
Robert Hooke made a compound microscope that had a lamp for lighting specimens. The light was focused onto the specimen and it could be seen in greater detail – not just the outline. He called the little rooms he saw CELLS.
A light microscope uses light to see a specimen
So who invented this technology? In about 1674, a Dutch fabric merchant
named Anthony van Leeuwenhoek began fiddling with ways to see the threads of his fabrics better.
So who invented this technology? He began looking at pond water and
discovered that it was ALIVE! He gave these tiny creatures the nickname “animalcules.” (write next to 1674)
So who invented this technology? Anthony also began finding interesting
stuff everywhere – even in the gunk on his own teeth! He eventually made microscopes that could magnify 266 times. He also was the first to see bacteria. (Not bad for a non-scientist type!) Leeuwenhoek sent
drawings like this to the Royal Society of London
So who invented this technology? In about 1880, a German named Carl
Zeiss began making REALLY good compound light microscopes, and we saw individual cells for the first time. He perfected his lenses by using Math calculations.
So who invented this technology? Even now, most good microscopes are
made in Germany or Japan. The cheap ones that you can buy as part of a science kit have plastic lenses that aren’t that great.
So who invented this technology? In 1933, a German named Ernst Ruska
created the first electron microscope. Transmission Electron Microscopes (TEM) send electrons through very thinly sliced specimens. They can magnify up to 500,000 times.
Organelles inside of a cell.
So who invented this technology? In 1965, Scanning Electron Microscopes
were invented. These send electrons over the surface of a specimen and create images that are almost like 3-D.
So who invented this technology? In 1981, the Scanning Tunneling
Microscope was invented. These measure electrons that leak from the surface of a specimen. These are the type used to “look” inside cells and cell organelles.
Silicon molecule through STM