Plant Drug Used In The Management of CANCER

Seminar Presented By:Asad Shah

Under the guidence of:

Ms P.P Udapurkar(M.Pharm)

IntroductionPlant drugs

Contents

Cancer, also known as a malignant tumor or malignant neoplasm, is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

A neoplasm or tumor is a group of cells that have undergone unregulated growth, and will often form a mass or lump, but may be distributed diffusely.

Introduction

Possible signs and symptoms include: a new lump, abnormal bleeding, a prolonged cough, unexplained weight loss, and a change in bowel movements among others.

While these symptoms may indicate cancer, they may also occur due to other issues.

When cancer begins, it invariably produces no symptoms. Signs and symptoms only appear as the mass continues to grow or ulcerates. The findings that result depend on the type and location of the cancer.

Sign and Symptoms

Mutation of Cancer

Cancers are caused by a series of mutations. Each mutation alters the behavior of the cell somewhat.

VINCA

WITHANIA SOMNIFERA

PODOPHYLLUM

CASCARA BARK

TURMERIC

GARLIC

Medicinal Plants used in the Treatment of Cancer

Synonyms and Regional name: Vinca roseaSadaphuli, Rattanjot; Hindi-

Sadabahar Biological source: It is dried whole plant of Catharanthus

roseus. Family: Apocynaceae

1.VINCA

1. Indole and indoline alkaloids:Ajmalicine,Lochnerine,Serpentine and2. Tetrahydroalstonine: Dimeric Indole bases of monoterpene type Vinblastin,Vincristin.

CHEMICAL CONSTITUENTS

Synonym; Ashwagandha,Asgandh Biological Source:It is dried root and rhizomes of the plan

Withania somnifera.Family; Solanaceae

2.WITHANIA

Alkaloids Withanolide A , withaferine, Withanone etc

Chemical constituent

Synonyms:Indian Podophyllum, Podophyllum radix.

Biological source: It consists of the dried rhizome and root of

Podophyllum hexandrum Royl. American podophyllum consists of dried rhizomes and roots of P. peltatum.

Family: Berbiridiaceae

3.Podophyllum

It contains Podophyllin resin is known as podophyllotoxin. α and β peltatins are present only in the American podophyllum.

Chemical constituents

Synonyms chittenbark;Persian bark;

Bearbark, Bearwood; Cascara bark; Rhamni purshianae.

Biological Source Cascara sagrada is the dried bark of

Rhamanus purshianaDC., family Rhamnaceae,.

4.Cascara Bark

The cascara sagrada bark is found to contain two major types of anthracene compounds, namely:Normal O-Glycosides and Aloin-like C-Glycosides .

The two C-glycosides are known as barbaloin and deoxybarbaloin.

Chemical constituents

Synonyms : Curcuma; Indian Saffron; Tumeric. Biological Source: Turmeric is obtained from the rhizome of

Curcuma longa Linn. Famiily:Zingiberaceae.

5.Turmeric

it contains volatile oil (5-6%), resin and substantial quantity of zingiberaceous starch grains. The marked and pronounced yellow colour in turmeric is due to the presence of curcuminoids which essentially contains curcumin.

Chemical constituents

Synonyms: Lehsun, Rasun, Belluli, Vallaippundu, Garlic.

Biological source: Lehsun consists of the fresh compound

bulb of Allium sativum Linn. Family:

Liliaceae.

6.Garlic

Essential oil: Alliin, a sulphur containing amino acid. Allicin- allyl sulphide.

Polysulphide responsible for the unpleasant smell of the oil

Amino acid: Leucine, methionine, Vitamins: A, B, C and D Fatty acid, mucilage and albumin. Minerals: Calcium, Iron and Zin

Chemical constituents

Wikipediia Text book of Pharmacognosy by

Gokhle,Kokate and Prohit Practical Pharmacognosy by Khandelwal www.pharmacognosydrugs.com www.yourarticlelibrary.com

Reference

DRUGS IN MARKET

THANK YOU