medicinal plants and cancer research at st. thomas university
DESCRIPTION
Presented by Dr. Wim Steelant, Dean of the St. Thomas University School of Science, Technology, and Engineering Management. Part of the University Library's celebration of Earth Week 2012.TRANSCRIPT
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St Thomas UniversitySchool of Science, Technology& Engineering Management
Medicinal PlantsAnd
Cancer Research at STU
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Science Building
Carnival Cruise Lines Science & Technology Building
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Medicinal Plants
Why medicinal plants & cancer research ???
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Medicinal Plants
Ligusticum porteri & Anemopsis californica
Laboratory of Biochemical and Biomedical ResearchCreated in 2004, New Mexico, USA
Biomembrane Structure, Interaction and Signal Transduction
New Medicinal Agents against Diseases
- Native American Medicine man- Ketowa Indian (Cherokee Nation)- Folk medicine with local plants
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Importance of Medicinal Plants
• Common names: Loveroot, Porter’s Lovage, Osha,Chuchupate, and Wild Parsley• Location: In the West, Canada to MexicoEspecially the Rocky Mountain region
• Common names: Lizard Tail, Swamp Root, Yerba Mansa
• Common Location: Wet, swampy areas
Medicine man recommended two medicinal plants: Ligusticum porteri (Osha) and Anemopsis californica (Yerba Mansa)
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Willow tree Salicin Acetyl-salicylic acid
“Miracle drug”- pain/fever reducer- blood thinner against strokes- acts against cancer- acts against Alzheimer
Importance of Medicinal Plants
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Importance of Medicinal Plants
Pacific Yew tree Paclitaxel/Taxol
Used in Cancer Chemotherapy- Discovered in 1967, due to a plant screening by the NCI- In 2000, 1.6 billion US$
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Importance of Medicinal Plants
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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Flower
Leaf
Root
Importance of Medicinal Plants
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
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USDA-FS and STU
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012
Ardesia crenata Pyrus calleryana
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Interdisciplinary!
Biological activity testing
AntibacterialAntifungal
Freeze-Dry
Anticancer
Harvest/Voucher specimen
Dried and ground plants
Leafs/roots/flowers
Extraction
Activity
Fractionation
Structure identification
Wim F.A. Steelant, CE, Ph.D., April 12th , 2012